MCID: HRN019
MIFTS: 16

Hair-an Syndrome

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Hair-an Syndrome

MalaCards integrated aliases for Hair-an Syndrome:

Name: Hair-an Syndrome 53 73
Hyperandrogenism , Insulin Resistance , and Acanthosis Nigricans 53
Hyperandrogenic, Insulin-Resistant Acanthosis Nigricans Syndrome 53

Classifications:



External Ids:

UMLS 73 C1963745

Summaries for Hair-an Syndrome

NIH Rare Diseases : 53 HAIR-AN syndrome is a condition that affects women. It is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. Insulin resistance is a condition in which the body produces insulin but does not use it properly. This causes the pancreas to produce more insulin. High levels of insulin stimulate the ovaries to make too much androgen, leading too excessive  hair growth, acne, and irregular periods. Insulin resistance can also lead to diabetes, high blood pressure, heart disease, and excessive growth and darkening of the skin (aconthosis nigricans). Women with HAIR-AN may be born with insulin resistance or acquire it over time.

MalaCards based summary : Hair-an Syndrome, also known as hyperandrogenism , insulin resistance , and acanthosis nigricans, is related to acanthosis nigricans and diabetes mellitus, noninsulin-dependent. Affiliated tissues include ovary, skin and pancreas.

Wikipedia : 76 HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans... more...

Related Diseases for Hair-an Syndrome

Diseases in the Hair Disease family:

Hair-an Syndrome

Diseases related to Hair-an Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 acanthosis nigricans 9.8
2 diabetes mellitus, noninsulin-dependent 9.8
3 hyperandrogenism 9.8
4 diabetes mellitus 9.6
5 disease of mental health 9.6
6 mood disorder 9.6

Graphical network of the top 20 diseases related to Hair-an Syndrome:



Diseases related to Hair-an Syndrome

Symptoms & Phenotypes for Hair-an Syndrome

Drugs & Therapeutics for Hair-an Syndrome

Search Clinical Trials , NIH Clinical Center for Hair-an Syndrome

Genetic Tests for Hair-an Syndrome

Anatomical Context for Hair-an Syndrome

MalaCards organs/tissues related to Hair-an Syndrome:

41
Ovary, Skin, Pancreas, Heart

Publications for Hair-an Syndrome

Articles related to Hair-an Syndrome:

(show all 13)
# Title Authors Year
1
HAIR-AN syndrome in a male adolescent with concomitant vitiligo. ( 19380681 )
2009
2
Navigating adolescence with a chronic health condition: a perspective on the psychological effects of HAIR-AN syndrome on adolescent girls. ( 17072487 )
2006
3
Biliopancreatic diversion as a novel approach to the HAIR-AN syndrome. ( 15802076 )
2005
4
Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome. ( 15258677 )
2004
5
HAIR-AN syndrome: a multisystem challenge. ( 11430453 )
2001
6
Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: an 11-year follow-up. ( 10474728 )
1999
7
Development of diabetes mellitus and hypertension due to aggravation of insulin resistance after estrogen--progestogen in HAIR-AN syndrome. ( 11229194 )
1997
8
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy. ( 9126004 )
1997
9
Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl. ( 8621823 )
1996
10
HAIR-AN syndrome and mental disorders. ( 8555759 )
1995
11
[HAIR-AN syndrome]. ( 7983793 )
1994
12
Organic mood disorder associated with the HAIR-AN syndrome. ( 1627962 )
1992
13
Effect of ketoconazole in the hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome. ( 1430411 )
1992

Variations for Hair-an Syndrome

Expression for Hair-an Syndrome

Search GEO for disease gene expression data for Hair-an Syndrome.

Pathways for Hair-an Syndrome

GO Terms for Hair-an Syndrome

Sources for Hair-an Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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