MCID: HRF001
MIFTS: 24

Hair Follicle Neoplasm

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Hair Follicle Neoplasm

MalaCards integrated aliases for Hair Follicle Neoplasm:

Name: Hair Follicle Neoplasm 12 15 74
Hair Matrix Neoplasm 12
Hair Matrix Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5375
NCIt 51 C7367
SNOMED-CT 69 44155009
UMLS 74 C0859920

Summaries for Hair Follicle Neoplasm

MalaCards based summary : Hair Follicle Neoplasm, also known as hair matrix neoplasm, is related to skin pilomatrix carcinoma and esophageal basaloid squamous cell carcinoma. An important gene associated with Hair Follicle Neoplasm is CTNNB1 (Catenin Beta 1), and among its related pathways/superpathways are Developmental Biology and Keratinization. Affiliated tissues include skin, and related phenotypes are craniofacial and digestive/alimentary

Related Diseases for Hair Follicle Neoplasm

Graphical network of the top 20 diseases related to Hair Follicle Neoplasm:



Diseases related to Hair Follicle Neoplasm

Symptoms & Phenotypes for Hair Follicle Neoplasm

MGI Mouse Phenotypes related to Hair Follicle Neoplasm:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.65 CTNNB1 HOXC13 KRT14 KRT17 OVOL2
2 digestive/alimentary MP:0005381 9.55 CTNNB1 HOXC13 KRT14 KRT17 OVOL2
3 integument MP:0010771 9.35 CASP14 CTNNB1 HOXC13 KRT14 KRT17
4 pigmentation MP:0001186 8.8 CTNNB1 KRT14 KRT17

Drugs & Therapeutics for Hair Follicle Neoplasm

Search Clinical Trials , NIH Clinical Center for Hair Follicle Neoplasm

Genetic Tests for Hair Follicle Neoplasm

Anatomical Context for Hair Follicle Neoplasm

MalaCards organs/tissues related to Hair Follicle Neoplasm:

42
Skin

Publications for Hair Follicle Neoplasm

Variations for Hair Follicle Neoplasm

Expression for Hair Follicle Neoplasm

Search GEO for disease gene expression data for Hair Follicle Neoplasm.

Pathways for Hair Follicle Neoplasm

Pathways related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.57 CASP14 CTNNB1 KRT14 KRT17 TCHH
2
Show member pathways
11.38 CASP14 KRT14 KRT17 TCHH
3 11.23 CTNNB1 KRT14
4 11.07 KRT14 KRT17

GO Terms for Hair Follicle Neoplasm

Cellular components related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.96 CASP14 KRT14
2 cell periphery GO:0071944 8.8 CTNNB1 KRT14 KRT17

Biological processes related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.46 CASP14 KRT14 KRT17 TCHH
2 dorsal/ventral pattern formation GO:0009953 9.37 CTNNB1 OVOL2
3 hair follicle morphogenesis GO:0031069 9.32 CTNNB1 KRT17
4 intermediate filament organization GO:0045109 9.26 KRT17 TCHH
5 cornification GO:0070268 9.26 CASP14 KRT14 KRT17 TCHH
6 epidermis development GO:0008544 8.92 CASP14 KRT14 KRT17 OVOL2

Molecular functions related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 9.16 KRT14 KRT17
2 chromatin binding GO:0003682 9.13 CTNNB1 HOXC13 OVOL2
3 transition metal ion binding GO:0046914 8.62 S100A3 TCHH

Sources for Hair Follicle Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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