MCID: HRF001
MIFTS: 21

Hair Follicle Neoplasm

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Hair Follicle Neoplasm

MalaCards integrated aliases for Hair Follicle Neoplasm:

Name: Hair Follicle Neoplasm 12 15 73
Hair Matrix Neoplasm 12
Hair Matrix Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5375
NCIt 50 C7367
SNOMED-CT 68 44155009
UMLS 73 C0859920

Summaries for Hair Follicle Neoplasm

MalaCards based summary : Hair Follicle Neoplasm, also known as hair matrix neoplasm, is related to skin pilomatrix carcinoma and esophageal basaloid squamous cell carcinoma. An important gene associated with Hair Follicle Neoplasm is CTNNB1 (Catenin Beta 1), and among its related pathways/superpathways are Keratinization and Corticotropin-releasing hormone signaling pathway. Affiliated tissues include skin, and related phenotypes are craniofacial and digestive/alimentary

Related Diseases for Hair Follicle Neoplasm

Diseases related to Hair Follicle Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 skin pilomatrix carcinoma 10.1 CTNNB1 HOXC13
2 esophageal basaloid squamous cell carcinoma 10.0 CTNNB1 KRT14
3 epidermoid cysts 9.9 S100A3 TCHH
4 craniopharyngioma 9.9 CTNNB1 KRT14
5 pilomatrixoma 9.8 CTNNB1 S100A3 TCHH
6 basal cell carcinoma 9.8 CTNNB1 KRT14 TCHH

Graphical network of the top 20 diseases related to Hair Follicle Neoplasm:



Diseases related to Hair Follicle Neoplasm

Symptoms & Phenotypes for Hair Follicle Neoplasm

MGI Mouse Phenotypes related to Hair Follicle Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 CTNNB1 HOXC13 KRT14 OVOL2
2 digestive/alimentary MP:0005381 8.92 CTNNB1 HOXC13 KRT14 OVOL2

Drugs & Therapeutics for Hair Follicle Neoplasm

Search Clinical Trials , NIH Clinical Center for Hair Follicle Neoplasm

Genetic Tests for Hair Follicle Neoplasm

Anatomical Context for Hair Follicle Neoplasm

MalaCards organs/tissues related to Hair Follicle Neoplasm:

41
Skin

Publications for Hair Follicle Neoplasm

Variations for Hair Follicle Neoplasm

Expression for Hair Follicle Neoplasm

Search GEO for disease gene expression data for Hair Follicle Neoplasm.

Pathways for Hair Follicle Neoplasm

Pathways related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.25 CASP14 KRT14 TCHH
2 10.92 CTNNB1 KRT14

GO Terms for Hair Follicle Neoplasm

Cellular components related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.96 CASP14 KRT14
2 cell periphery GO:0071944 8.62 CTNNB1 KRT14

Biological processes related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.33 CASP14 KRT14 TCHH
2 dorsal/ventral pattern formation GO:0009953 9.26 CTNNB1 OVOL2
3 cornification GO:0070268 9.13 CASP14 KRT14 TCHH
4 epidermis development GO:0008544 8.8 CASP14 KRT14 OVOL2

Molecular functions related to Hair Follicle Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.13 CTNNB1 HOXC13 OVOL2
2 transition metal ion binding GO:0046914 8.62 S100A3 TCHH

Sources for Hair Follicle Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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