Aliases & Classifications for Hair Whorl

MalaCards integrated aliases for Hair Whorl:

Name: Hair Whorl 57
Cowlick; Crown 57
Cowlick 57
Crown 57

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant


HPO:

32
hair whorl:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 57 139400
MedGen 42 C1185616
SNOMED-CT via HPO 69 263681008

Summaries for Hair Whorl

MalaCards based summary : Hair Whorl, also known as cowlick; crown, is related to amelogenesis imperfecta and gingival recession. An important gene associated with Hair Whorl is RHD (Rh Blood Group D Antigen). The drugs Methamphetamine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include kidney and bone, and related phenotype is abnormality of the hair.

Wikipedia : 76 A hair whorl is a patch of hair growing in a circular direction around a visible center point. Hair... more...

Description from OMIM: 139400

Related Diseases for Hair Whorl

Diseases related to Hair Whorl via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 amelogenesis imperfecta 11.4
2 gingival recession 11.4
3 bruxism 11.2
4 mental retardation, x-linked, syndromic, nascimento type 11.2
5 syndromic x-linked intellectual disability nascimento type 11.2
6 dentin dysplasia, type i 11.1
7 temple-baraitser syndrome 11.1
8 dentin dysplasia, type ii 11.1
9 solitary median maxillary central incisor 11.1
10 pericoronitis 11.1
11 alopecia, androgenetic, 1 10.9
12 dentinogenesis imperfecta 1 10.9
13 dentinogenesis imperfecta, shields type iii 10.9
14 amelogenesis imperfecta, type iiia 10.9
15 fibromatosis, gingival, 1 10.9
16 incisors, fused mandibular 10.9
17 incisors, shovel-shaped 10.9
18 otodental dysplasia 10.9
19 witkop syndrome 10.9
20 nance-horan syndrome 10.9
21 ectodermal dysplasia-syndactyly syndrome 1 10.9
22 fibromatosis, gingival, 5 10.9
23 charlie m syndrome 10.9
24 dentinogenesis imperfecta type 2 10.9
25 dentinogenesis imperfecta type 3 10.9
26 ichthyosis prematurity syndrome 10.3
27 tooth size 10.2
28 schizophrenia 10.1
29 down syndrome 10.1
30 dental pulp necrosis 10.1
31 ventricular fibrillation, paroxysmal familial, 1 10.0
32 periodontitis 10.0
33 meningitis 10.0
34 pseudofolliculitis barbae 10.0
35 plexiform neurofibroma 10.0
36 neurofibroma 10.0
37 adamantinoma of long bones 10.0
38 aging 10.0
39 ectodermal dysplasia 10.0
40 periodontal disease 10.0
41 retinoblastoma 9.9
42 teeth present at birth 9.9
43 temporal arteritis 9.9
44 myopathy, myosin storage, autosomal dominant 9.9
45 human immunodeficiency virus type 1 9.9
46 pulpitis 9.9
47 root caries 9.9
48 dental caries 9.9
49 bursitis 9.9
50 gingivitis 9.9

Graphical network of the top 20 diseases related to Hair Whorl:



Diseases related to Hair Whorl

Symptoms & Phenotypes for Hair Whorl

Symptoms via clinical synopsis from OMIM:

57
Hair:
occipital scalp hair whorl rotation


Clinical features from OMIM:

139400

Human phenotypes related to Hair Whorl:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the hair 32 HP:0001595

Drugs & Therapeutics for Hair Whorl

Drugs for Hair Whorl (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 371)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methamphetamine Approved, Illicit Phase 4,Not Applicable 537-46-2 10836
2
Dopamine Approved Phase 4,Phase 3,Not Applicable 51-61-6, 62-31-7 681
3
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55-56-1 2713 9552079
4
Ibuprofen Approved Phase 4,Phase 2,Not Applicable 15687-27-1 3672
5
Amoxicillin Approved, Vet_approved Phase 4,Not Applicable 26787-78-0 33613
6 sodium fluoride Approved Phase 4,Phase 3,Phase 2,Not Applicable 7681-49-4
7
Silicon Approved, Investigational Phase 4,Phase 2,Phase 1 7440-21-3 4082203
8
Alginic acid Approved, Investigational Phase 4,Not Applicable 9005-32-7
9
Misoprostol Approved Phase 4 59122-46-2 5282381
10
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
11
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
12
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
13
Ethanol Approved Phase 4,Phase 2,Not Applicable 64-17-5 702
14
Cetylpyridinium Approved Phase 4,Phase 3,Phase 1,Phase 2 7773-52-6
15
Acetaminophen Approved Phase 4 103-90-2 1983
16
Triclosan Approved, Investigational Phase 4,Phase 3,Phase 2 3380-34-5 5564
17
Levodopa Approved Phase 4 59-92-7 6047
18
Carbidopa Approved Phase 4 28860-95-9 34359 38101
19
Nicotine Approved Phase 4,Phase 1,Phase 2 54-11-5 942 89594
20
Omalizumab Approved, Investigational Phase 4 242138-07-4
21
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
22
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
23
Bismuth Phase 4,Phase 2,Early Phase 1,Not Applicable 7440-69-9 16682734 105143
24 Bone Density Conservation Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
25 Calcium, Dietary Phase 4,Phase 2,Phase 3,Not Applicable
26 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Central Nervous System Depressants Phase 4,Phase 3,Not Applicable
28 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 Anesthetics, Local Phase 4,Not Applicable
30 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
31 Sympathomimetics Phase 4,Not Applicable
32 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Not Applicable
33 Dopamine Uptake Inhibitors Phase 4,Not Applicable
34 Central Nervous System Stimulants Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
35 Dopamine Agents Phase 4,Phase 3,Not Applicable
36 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Adrenergic Agents Phase 4,Phase 2,Not Applicable
38 Autonomic Agents Phase 4,Phase 1,Phase 2,Not Applicable
39 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
40 Chlorhexidine gluconate Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
42 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Not Applicable
43 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
45 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
46 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Anti-Infective Agents, Local Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Disinfectants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 452)
# Name Status NCT ID Phase Drugs
1 Clinical Comparison of RPDs Retained by Conical and Galvanoformed Double Crowns. Unknown status NCT00176215 Phase 4
2 Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT Unknown status NCT02702505 Phase 4
3 Pinhole Surgical Technique With And Without Use Of Buttons For Treatment Of Multiple Gingival Recessions: RCT Unknown status NCT02632968 Phase 4
4 Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair Unknown status NCT00625053 Phase 4
5 Zirconia and Metal-based Single Crown Posterior Restorations. Completed NCT02758457 Phase 4
6 Benefit of the Digital Workflow for Screw-retained Single Implant Restorations Completed NCT03234868 Phase 4
7 Effect of Alveolar Ridge Preservation on Implant Esthetic Outcomes Completed NCT02507661 Phase 4 preservation of alveolar ridge with beta tricalcium phosphate + collagen - 2 months;no-preservation of alveolar ridge - 2 months;preservation of alveolar ridge with beta tricalcium phosphate + collagen - 4 months;no-preservation of alveolar ridge - 4 months;no-preservation of alveolar ridge - 9 months
8 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial Recruiting NCT02639429 Phase 4 Vaginal Misoprostol
9 Early Vascular Healing in Acute Coronary Syndrome Patients With Different Doses of Rosuvastatin Recruiting NCT03007524 Phase 4 High dose Rosuvastatin;Low dose Rosuvastatin
10 Bone Dimensional Changes at Different Implant-to-abutment Connections: a 1-year Clinical and Radiological Study Completed NCT01807416 Phase 4
11 the Effect of Topical Application of Hyaluronic Acid on Immediate Dental Implant Not yet recruiting NCT03691467 Phase 4 Hyaluronic Acid
12 Peri-implant Bone Changes in Post-menopausal Osteoporotic Women Recruiting NCT02884401 Phase 4
13 Customized Titanium Membrane for Growing Jaw Bone Horizontally Withdrawn NCT02227719 Phase 4
14 The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region Not yet recruiting NCT03804177 Phase 4
15 Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation Completed NCT02097017 Phase 4 Lidocaine
16 Prefabricated Endodontic Posts: Glass Fiber Versus Titanium - A Randomized Controlled Pilot- Trial Completed NCT01520766 Phase 4
17 Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy Terminated NCT01030666 Phase 4 Doxycycline;Placebo;0.12% chlorhexidine gluconate solution;Ibuprofen 400 mg (if necessary);1% chlorhexidine gluconate gel (if necessary)
18 Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures Completed NCT01383616 Phase 4
19 Comparison of Two Embryo Transfer Catheters in Patients Undergoing in Vitro Fertilization and Embryo Transfer Recruiting NCT02024880 Phase 4
20 Cost- Effectiveness and Cost-utility of Laparoscopic Versus Open Repair of Ventral Hernia Completed NCT01778387 Phase 4
21 An Efficacy Study of Chlorhexidine Mouthwashes Completed NCT01751178 Phase 4 Chlorhexidine Digluconate Mouthwash with Alcohol;Chlorhexidine Digluconate Mouthwash without Alcohol
22 Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis Active, not recruiting NCT03219840 Phase 4 CPC;Placebo
23 Impact of Soft Tissue Grafts on Tissue Alterations After Immediate Tooth Replacement Completed NCT02922075 Phase 4 Post operative medication
24 Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control Active, not recruiting NCT03099551 Phase 4
25 Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash) Completed NCT02366689 Phase 4 Triclosan/fluoride toothpaste;stannous fluoride toothpaste;fluoride only toothpaste;Cetylpyridinium chloride mouthwash;Fluoride only mouthwash
26 The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US Completed NCT02360995 Phase 4 Triclosan/fluoride toothpaste;stannous fluoride toothpaste;fluoride toothpaste;Fluoride Mouthwash;cetylpyridinium chloride Mouthwash
27 Postoperative Pain in Single-visit and Multiple-visit Retreatment Cases Completed NCT03042377 Phase 4 Multiple-Visit-"Calcium Hydroxide";Multiple-Visit-"Corticosteroid Paste";Multiple-Visit-"Antibiotic Paste"
28 Long-term Study of Duodopa (Levodopa/Carbidopa) in Advanced Parkinson's: Health Outcomes & Net Economic Impact Completed NCT00141518 Phase 4 Levodopa-carbidopa intestinal gel (LCIG)
29 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs Completed NCT02515929 Phase 4
30 Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste Completed NCT02080273 Phase 4 Colgate Cavitity Protection toothpaste;Colgate Total toothpaste;Parodontax toothpaste
31 Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites Recruiting NCT03315910 Phase 4 Nicotine Replacement Therapy (NRT);Nicotine Lozenge
32 A Study in Participants With Asthma Initiating Treatment With Omalizumab (Xolair) Completed NCT01922037 Phase 4 Omalizumab
33 SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma. Completed NCT01475721 Phase 4 ADVAIR 100/50mcg;ADVAIR 250/50mcg;ADVAIR 500/50mcg;FLOVENT 100mcg;FLOVENT 250mcg;FLOVENT 500mcg
34 6-month Safety and Benefit Study of ADVAIR in Children 4-11 Years Old Completed NCT01462344 Phase 4 ADVAIR 100/50mcg;ADVAIR 250/50mcg;FLOVENT 100mcg;FLOVENT 250mcg
35 Treatment of Salivary Gland Hypofunction With Neuro- Electrostimulation Unknown status NCT01174329 Phase 2, Phase 3
36 Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth Unknown status NCT02799927 Phase 2, Phase 3
37 A Clinical Trial of an Acetal Resin Crown for Restoration of Primary Molars Completed NCT01359475 Phase 3
38 Clinical Comparison of Endodontically Treated Teeth Restored With Fiber Posts or Cast Metal Posts Recruiting NCT01461239 Phase 3
39 Controlled Trial of Prenatal Vitamin D3 Supplementation to Prevent Vitamin D Deficiency in Mothers and Their Infants Completed NCT00610688 Phase 3 Prenatal Vitamin;Cholecalciferol (Vitamin D3);Cholecalciferol (Vitamin D3)
40 Comparison of Peri Implant Soft Tissue Esthetics With Immediate Temporization With and Without Subepithelial Connective Tissue Graft Not yet recruiting NCT03770975 Phase 3
41 Evaluate Clinical Research From Commerical Oral Care Products Completed NCT00759187 Phase 3 Fluoride;Triclosan/Fluoride;Chlorhexidine Gluconate
42 Improving Patient-centered Care Using an Inventory Completed NCT01843803 Phase 2, Phase 3
43 Dutasteride Versus Placebo and Finasteride in Men With Androgenetic Alopecia Completed NCT01231607 Phase 3 1mg Finasteride active;0.02mg dutasteride;0.1mg dutasteride;0.5mg dutasteride;Finasteride placebo;Dutasteride placebo
44 Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes Completed NCT00762515 Phase 3 Fluoride;Triclosan;Fluoride
45 Immediate Implant Placement With or Without Connective Tissue Graft Recruiting NCT03594019 Phase 3
46 Compare the Clinical Efficacy of Prototype Toothpastes Completed NCT00926029 Phase 3 Fluoride;Triclosan, fluoride
47 Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis Completed NCT00926328 Phase 3 Triclosan, fluoride;Fluoride
48 Comparison of Peri-implant Tissues Using Socket Shield Technique Versus Xenograft Not yet recruiting NCT03684356 Phase 3
49 Prevention of Adult Caries Study (PACS) Completed NCT00357877 Phase 3 10% w/v chlorhexidine acetate coating FDA IND #45466
50 Growth Hormone in Poor Responders to IVF Trial Terminated NCT01616225 Phase 2, Phase 3 Saizen (Human Growth Hormone);Saizen (Human Growth Hormone);No Saizen Control (Standard IVF Protocol)

Search NIH Clinical Center for Hair Whorl

Genetic Tests for Hair Whorl

Anatomical Context for Hair Whorl

MalaCards organs/tissues related to Hair Whorl:

41
Kidney, Bone

Publications for Hair Whorl

Articles related to Hair Whorl:

(show all 28)
# Title Authors Year
1
Multiple-opposing rotation flaps for the scalp defect including hair whorl. ( 28636154 )
2017
2
Scalp hair-whorl orientation of Japanese individuals is random; hence, the trait's distribution is not genetically determined. ( 19049888 )
2009
3
Hair whorl direction and sexual orientation in human males. ( 19331448 )
2009
4
Human handedness and scalp hair whorl direction: no evidence for a common cause. ( 18853354 )
2009
5
Dermatoglyphic asymmetry and hair whorl patterns in schizophrenic and bipolar patients. ( 17931706 )
2008
6
Medial position and counterclockwise rotation of the parietal scalp hair-whorl as a possible indicator for non-right-handedness. ( 18758663 )
2008
7
Direction of hair whorl and handedness. ( 17558812 )
2007
8
The association between scalp hair-whorl direction, handedness and hemispheric language dominance: is there a common genetic basis of lateralization? ( 17275334 )
2007
9
The genetic basis of hair whorl, handedness, and other phenotypes. ( 16337093 )
2006
10
Heritability of hair whorl position on the forehead in Konik horses. ( 17177695 )
2006
11
Association between scalp hair-whorl direction and hemispheric language dominance. ( 16289721 )
2006
12
Phenotypic relationships between hair whorl characteristics and spermatozoal attributes in Holstein bulls. ( 15556312 )
2005
13
A 1927 study supports a current genetic model for inheritance of human scalp hair-whorl orientation and hand-use preference traits. ( 15944357 )
2005
14
Excess of counterclockwise scalp hair-whorl rotation in homosexual men. ( 15689627 )
2004
15
Hair whorl patterns on the bovine forehead may be related to breeding soundness measures. ( 15226001 )
2004
16
Human handedness and scalp hair-whorl direction develop from a common genetic mechanism. ( 14504234 )
2003
17
A note on hair whorl position and cattle temperament in the auction ring. ( 11358607 )
2001
18
Hair whorl as an indicator of a mediastinal plexiform neurofibroma. ( 9192411 )
1997
19
Parietal scalp hair whorl patterns in schizophrenia. ( 7711167 )
1995
20
Pseudofolliculitis barbae associated with an unusual hair whorl. ( 8453890 )
1993
21
Counter clockwise scalp hair whorl in schizophrenia. ( 1450299 )
1992
22
Hair whorl and handedness. ( 1930977 )
1991
23
Role of red light in hair-whorl formation induced by blue light in Acetabularia mediterranea. ( 24196687 )
1990
24
Transient reduction of responsiveness of blue-light-mediated hair-whorl morphogenesis inAcetabularia mediterranea induced by blue light. ( 24221519 )
1988
25
Hair crown patterns of human newborns. Studies on parietal hair whorl locations and their directions. ( 1183129 )
1975
26
Occipital hair whorl as a racial criterion: a critical assessment. ( 5686940 )
1968
27
The hair whorl sign for handedness. ( 14936861 )
1952
28
The mid-dorsal hair whorl in an Australian of European ancestry. ( 17104904 )
1942

Variations for Hair Whorl

Expression for Hair Whorl

Search GEO for disease gene expression data for Hair Whorl.

Pathways for Hair Whorl

GO Terms for Hair Whorl

Sources for Hair Whorl

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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