Aliases & Classifications for Hair Whorl

MalaCards integrated aliases for Hair Whorl:

Name: Hair Whorl 56
Cowlick; Crown 56
Cowlick 56
Crown 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
hair whorl:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 139400
MedGen 41 C1185616
SNOMED-CT via HPO 68 263681008

Summaries for Hair Whorl

MalaCards based summary : Hair Whorl, also known as cowlick; crown, is related to gingival recession and amelogenesis imperfecta. An important gene associated with Hair Whorl is RHD (Rh Blood Group D Antigen). The drugs Salicylic acid and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and heart, and related phenotype is abnormal hair morphology.

Wikipedia : 74 A hair whorl is a patch of hair growing in a circular direction around a visible center point. Hair... more...

More information from OMIM: 139400

Related Diseases for Hair Whorl

Diseases related to Hair Whorl via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 306, show less)
# Related Disease Score Top Affiliating Genes
1 gingival recession 11.6
2 amelogenesis imperfecta 11.6
3 bruxism 11.4
4 incisors, shovel-shaped 11.4
5 pericoronitis 11.4
6 dentinogenesis imperfecta type 2 11.4
7 dentin dysplasia, type i 11.3
8 temple-baraitser syndrome 11.3
9 mental retardation, x-linked, syndromic, nascimento type 11.3
10 cardiac, facial, and digital anomalies with developmental delay 11.3
11 syndromic x-linked intellectual disability nascimento type 11.3
12 dentin dysplasia, type ii 11.2
13 dentinogenesis imperfecta, shields type iii 11.2
14 solitary median maxillary central incisor 11.2
15 alopecia, androgenetic, 1 11.1
16 dentinogenesis imperfecta 1 11.1
17 amelogenesis imperfecta, type iiia 11.1
18 fibromatosis, gingival, 1 11.1
19 incisors, fused mandibular 11.1
20 otodental dysplasia 11.1
21 witkop syndrome 11.1
22 nance-horan syndrome 11.1
23 ectodermal dysplasia-syndactyly syndrome 1 11.1
24 fibromatosis, gingival, 5 11.1
25 androgenic alopecia 11.1
26 coronavirus infection 11.1
27 charlie m syndrome 11.1
28 tooth size 10.6
29 hand skill, relative 10.6
30 periodontitis 10.6
31 bone resorption disease 10.5
32 root resorption 10.5
33 gingivitis 10.5
34 teratoma 10.4
35 dental pulp necrosis 10.4
36 dental caries 10.4
37 down syndrome 10.4
38 47,xyy 10.3
39 chondrocalcinosis 10.3
40 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.3
41 chromosomal triplication 10.3
42 triiodothyronine receptor auxiliary protein 10.3
43 pulpitis 10.3
44 allergic hypersensitivity disease 10.3
45 48,xyyy 10.3
46 schizophrenia 10.3
47 turner syndrome 10.2
48 temporal arteritis 10.2
49 meningitis 10.2
50 polykaryocytosis inducer 10.2
51 gonadal dysgenesis 10.2
52 cleft lip/palate 10.2
53 leukemia, acute lymphoblastic 3 10.1
54 ectodermal dysplasia 10.1
55 ankylosis 10.1
56 rapidly involuting congenital hemangioma 10.1
57 human immunodeficiency virus type 1 10.1
58 alopecia, neurologic defects, and endocrinopathy syndrome 10.1
59 inflammatory spondylopathy 10.1
60 root caries 10.1
61 aggressive periodontitis 10.1
62 gingival overgrowth 10.1
63 thyroid hyalinizing trabecular adenoma 10.1
64 spondylitis 10.1
65 periapical periodontitis 10.1
66 headache 10.1
67 posttransplant acute limbic encephalitis 10.1
68 familial calcium pyrophosphate deposition 10.1
69 schistosoma mansoni infection, susceptibility/ 10.0
70 teeth, supernumerary 10.0
71 periodontitis, chronic 10.0
72 aging 10.0
73 helix syndrome 10.0
74 tooth agenesis 10.0
75 mucositis 10.0
76 non-alcoholic steatohepatitis 10.0
77 patau syndrome 10.0
78 schistosomiasis 10.0
79 alopecia 10.0
80 cleft palate, isolated 10.0
81 neurofibromatosis, type iv, of riccardi 10.0
82 autism 10.0
83 pseudofolliculitis barbae 10.0
84 major affective disorder 8 10.0
85 major affective disorder 9 10.0
86 autism spectrum disorder 10.0
87 stuttering 10.0
88 bipolar disorder 10.0
89 dyslexia 10.0
90 plexiform neurofibroma 10.0
91 cleft lip 10.0
92 neurofibroma 10.0
93 cleft lip with or without cleft palate 10.0
94 orofacial clefting syndrome 10.0
95 dowling-degos disease 1 10.0
96 immune deficiency disease 10.0
97 asplenia, isolated congenital 10.0
98 bulimia nervosa 10.0
99 necrotizing ulcerative gingivitis 10.0
100 placenta disease 10.0
101 appendicitis 10.0
102 stomatitis 10.0
103 dysphagia 10.0
104 overgrowth syndrome 10.0
105 aplasia cutis congenita, nonsyndromic 9.9
106 myositis 9.9
107 scleroderma, familial progressive 9.9
108 teeth present at birth 9.9
109 autoimmune lymphoproliferative syndrome 9.9
110 chudley-mccullough syndrome 9.9
111 anxiety 9.9
112 pulmonary hypertension, primary, 3 9.9
113 dental abscess 9.9
114 non-alcoholic fatty liver disease 9.9
115 osteomyelitis 9.9
116 thalassemia 9.9
117 hydrocephalus 9.9
118 tetanus 9.9
119 heart disease 9.9
120 frozen shoulder 9.9
121 oral candidiasis 9.9
122 rheumatic disease 9.9
123 synovitis 9.9
124 contact dermatitis 9.9
125 bursitis 9.9
126 bone inflammation disease 9.9
127 cellulitis 9.9
128 arthropathy 9.9
129 dentinogenesis imperfecta 9.9
130 infertility 9.9
131 dentin sensitivity 9.9
132 polycythemia 9.9
133 ileus 9.9
134 herpes simplex 9.9
135 eating disorder 9.9
136 keratoconjunctivitis 9.9
137 fatty liver disease 9.9
138 toxoplasmosis 9.9
139 hemophilia 9.9
140 47, xxy 9.9
141 odontoma 9.9
142 triploidy 9.9
143 arterial thoracic outlet syndrome 9.9
144 pik3ca-related overgrowth syndrome 9.9
145 alcohol dependence 9.7
146 alzheimer disease 9.7
147 spondyloarthropathy 1 9.7
148 aortic valve disease 1 9.7
149 breast cancer 9.7
150 cleidocranial dysplasia 9.7
151 creutzfeldt-jakob disease 9.7
152 optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy 9.7
153 dens evaginatus 9.7
154 dens in dente and palatal invaginations 9.7
155 multiple sclerosis 9.7
156 ear malformation 9.7
157 erythroleukemia, familial 9.7
158 lipomatosis, multiple 9.7
159 medulloblastoma 9.7
160 migraine with or without aura 1 9.7
161 otitis media 9.7
162 teratoma, ovarian 9.7
163 rheumatoid arthritis 9.7
164 neural tube defects 9.7
165 strabismus 9.7
166 tracheoesophageal fistula with or without esophageal atresia 9.7
167 tracheopathia osteoplastica 9.7
168 anencephaly 9.7
169 lung cancer 9.7
170 celiac disease 1 9.7
171 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 9.7
172 hemochromatosis, type 1 9.7
173 leprosy 3 9.7
174 familial mediterranean fever 9.7
175 netherton syndrome 9.7
176 osteoid osteoma 9.7
177 pancreatic cancer 9.7
178 phenylketonuria 9.7
179 gitelman syndrome 9.7
180 taurodontism 9.7
181 fragile x syndrome 9.7
182 mend syndrome 9.7
183 arts syndrome 9.7
184 tubulin, beta 9.7
185 fryns microphthalmia syndrome 9.7
186 yemenite deaf-blind hypopigmentation syndrome 9.7
187 tricuspid atresia 9.7
188 late-onset retinal degeneration 9.7
189 cataract 26, multiple types 9.7
190 body mass index quantitative trait locus 1 9.7
191 anorexia nervosa 9.7
192 coronary heart disease 1 9.7
193 preterm premature rupture of the membranes 9.7
194 ectodermal dysplasia-syndactyly syndrome 2 9.7
195 aspergillosis 9.7
196 muscle hypertrophy 9.7
197 hypertelorism, preauricular sinus, punctal pits, and deafness 9.7
198 hydrops, lactic acidosis, and sideroblastic anemia 9.7
199 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.7
200 tendinitis 9.7
201 foodborne botulism 9.7
202 lissencephaly 9.7
203 exanthem 9.7
204 variola major 9.7
205 secondary progressive multiple sclerosis 9.7
206 sleep apnea 9.7
207 fibroma 9.7
208 pain agnosia 9.7
209 metal allergy 9.7
210 keratoconus 9.7
211 osteonecrosis 9.7
212 pleomorphic lipoma 9.7
213 endocarditis 9.7
214 esophageal atresia 9.7
215 meningoencephalitis 9.7
216 pre-eclampsia 9.7
217 interstitial nephritis 9.7
218 hemiplegia 9.7
219 discitis 9.7
220 chronic apical periodontitis 9.7
221 epidural abscess 9.7
222 pulmonary edema 9.7
223 diphtheria 9.7
224 mitral valve insufficiency 9.7
225 polycystic ovary syndrome 9.7
226 cryptococcosis 9.7
227 aseptic meningitis 9.7
228 otosclerosis 9.7
229 olecranon bursitis 9.7
230 hypercementosis 9.7
231 acute cystitis 9.7
232 tooth resorption 9.7
233 eclampsia 9.7
234 anodontia 9.7
235 amenorrhea 9.7
236 calcific tendinitis 9.7
237 hypophosphatasia 9.7
238 glossitis 9.7
239 hypothyroidism 9.7
240 lymphangioma 9.7
241 gingival disease 9.7
242 angioedema 9.7
243 keratosis 9.7
244 duodenal ulcer 9.7
245 ossifying fibroma 9.7
246 hyperuricemia 9.7
247 exostosis 9.7
248 enthesopathy 9.7
249 sensory peripheral neuropathy 9.7
250 tooth erosion 9.7
251 kidney cancer 9.7
252 dermatitis 9.7
253 allergic contact dermatitis 9.7
254 rhabdomyosarcoma 9.7
255 mood disorder 9.7
256 breast disease 9.7
257 plague 9.7
258 choriocarcinoma 9.7
259 skin disease 9.7
260 hermaphroditism 9.7
261 granuloma annulare 9.7
262 syphilis 9.7
263 hyperglycemia 9.7
264 femoral neuropathy 9.7
265 reticulohistiocytic granuloma 9.7
266 holoprosencephaly 9.7
267 pneumonia 9.7
268 ovarian germ cell teratoma 9.7
269 congestive heart failure 9.7
270 conjunctivitis 9.7
271 macular holes 9.7
272 mite infestation 9.7
273 osteoarthritis 9.7
274 herpes zoster 9.7
275 chickenpox 9.7
276 neuropathy 9.7
277 smallpox 9.7
278 rubella 9.7
279 cervix uteri carcinoma in situ 9.7
280 amyloidosis 9.7
281 lichen planus 9.7
282 mechanical strabismus 9.7
283 viral infectious disease 9.7
284 diabetes mellitus 9.7
285 croup 9.7
286 hypoplastic left heart syndrome 9.7
287 cleidocranial dysplasia spectrum disorder 9.7
288 cerulean cataract 9.7
289 cervical intraepithelial neoplasia 9.7
290 colpocephaly 9.7
291 gigantism 9.7
292 hansen's disease 9.7
293 hemicrania continua 9.7
294 oral cancer 9.7
295 splenomegaly 9.7
296 brain injury 9.7
297 neuronal migration disorders 9.7
298 occipital neuralgia 9.7
299 traumatic brain injury 9.7
300 rare lymphatic malformation 9.7
301 lmna-related cardiocutaneous progeria syndrome 9.7
302 argyria 9.7
303 rare surgical neurologic disease 9.7
304 polyploidy 9.7
305 multiple system atrophy, parkinsonian type 9.7
306 hypoplastic amelogenesis imperfecta 9.7

Graphical network of the top 20 diseases related to Hair Whorl:



Diseases related to Hair Whorl

Symptoms & Phenotypes for Hair Whorl

Human phenotypes related to Hair Whorl:

31 (showing 1, show less)
# Description HPO Frequency HPO Source Accession
1 abnormal hair morphology 31 HP:0001595

Symptoms via clinical synopsis from OMIM:

56
Hair:
occipital scalp hair whorl rotation

Clinical features from OMIM:

139400

Drugs & Therapeutics for Hair Whorl

Drugs for Hair Whorl (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 270, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Salicylic acid Approved, Investigational, Vet_approved Phase 4 69-72-7 338
2
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
3
Methamphetamine Approved, Illicit Phase 4 537-46-2 10836
4
Zinc Approved, Investigational Phase 4 7440-66-6 32051
5
Zinc oxide Approved Phase 4 1314-13-2
6
Eugenol Approved Phase 4 97-53-0 3314
7
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
8
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
9
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
10
Morphine Approved, Investigational Phase 4 57-27-2 5288826
11
Codeine Approved, Illicit Phase 4 76-57-3 5284371
12
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
13
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
14
Racepinephrine Approved Phase 4 329-65-7 838
15
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
16
Metronidazole Approved Phase 4 443-48-1 4173
17
Cefixime Approved, Investigational Phase 4 79350-37-1 54362 5362065
18
Simvastatin Approved Phase 4 79902-63-9 54454
19
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
20
Iron Approved, Experimental Phase 4 7439-89-6, 15438-31-0 23925 27284
21
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
22
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
23
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
24
Sodium citrate Approved, Investigational Phase 4 68-04-2
25
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
26
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
27
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
28
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
29
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
30
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
31 Hormones Phase 4
32 Calcium, Dietary Phase 4
33 Carticaine Phase 4
34 Neurotransmitter Agents Phase 4
35 Sympathomimetics Phase 4
36 Dopamine Uptake Inhibitors Phase 4
37 Central Nervous System Stimulants Phase 4
38 Dopamine Agents Phase 4
39 Cyclooxygenase Inhibitors Phase 4
40
protease inhibitors Phase 4
41 HIV Protease Inhibitors Phase 4
42 Polymethyl Methacrylate Phase 4
43 Cholinergic Agents Phase 4
44 Calamus Phase 4
45 Narcotics Phase 4
46 Analgesics, Opioid Phase 4
47 BB 1101 Phase 4
48 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
49 Antitussive Agents Phase 4
50 Antineoplastic Agents, Hormonal Phase 4
51 glucocorticoids Phase 4
52 Antiemetics Phase 4
53 Epinephryl borate Phase 4
54 Antiparasitic Agents Phase 4
55 Antiprotozoal Agents Phase 4
56 Adrenergic Agonists Phase 4
57 Adrenergic beta-Agonists Phase 4
58 Vasoconstrictor Agents Phase 4
59 Mydriatics Phase 4
60
Procyanidin Phase 4 4852-22-6 147299
61 Proanthocyanidin Phase 4
62 Anthocyanidin Phase 4
63 Radiation-Protective Agents Phase 4
64 Sunscreening Agents Phase 4
65 Acetylcholine Release Inhibitors Phase 4
66 Neuromuscular Agents Phase 4
67 Botulinum Toxins Phase 4
68 abobotulinumtoxinA Phase 4
69 rimabotulinumtoxinB Phase 4
70 Botulinum Toxins, Type A Phase 4
71 Iron Supplement Phase 4
72 Anti-Infective Agents Phase 4
73 Nutrients Phase 4
74 Trace Elements Phase 4
75 Micronutrients Phase 4
76 Central Nervous System Depressants Phase 4
77 Anti-Bacterial Agents Phase 4
78 Protective Agents Phase 4
79 Disinfectants Phase 4
80 Vitamins Phase 4
81 Antioxidants Phase 4
82 Antibiotics, Antitubercular Phase 4
83 Antitubercular Agents Phase 4
84 Pharmaceutical Solutions Phase 4
85 Sodium hypochlorite Phase 4
86 Eusol Phase 4
87 Immunologic Factors Phase 4
88 Viscosupplements Phase 4
89 Adjuvants, Immunologic Phase 4
90 Clindamycin phosphate Phase 4
91 Clindamycin palmitate Phase 4
92 Citrate Phase 4
93 Amoxicillin-Potassium Clavulanate Combination Phase 4
94 beta-Lactamase Inhibitors Phase 4
95
Isosorbide Dinitrate Approved, Investigational Phase 3 87-33-2 6883
96
AT-101 Approved, Investigational Phase 3 90141-22-3, 652-67-5 12597
97
Nitric Oxide Approved Phase 3 10102-43-9 145068
98
Cysteine Approved, Nutraceutical Phase 3 52-90-4 5862
99
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
100
Pyridoxine Approved, Investigational, Nutraceutical, Vet_approved Phase 3 65-23-6 1054
101 Calpastatin Phase 3
102 Omega 3 Fatty Acid Phase 3
103 Insulin, Globin Zinc Phase 3
104 insulin Phase 3
105 Autonomic Agents Phase 3
106 Vitamin B Complex Phase 3
107 Vitamin B9 Phase 3
108 Folate Phase 3
109 Vasodilator Agents Phase 3
110 Respiratory System Agents Phase 3
111 Anti-Asthmatic Agents Phase 3
112 Bronchodilator Agents Phase 3
113 isosorbide-5-mononitrate Phase 3
114 Natriuretic Agents Phase 3
115 diuretics Phase 3
116 Nitric Oxide Donors Phase 3
117 Free Radical Scavengers Phase 3
118 Vitamin B 6 Phase 3
119
Pyridoxal Experimental, Nutraceutical Phase 3 66-72-8 1050
120 sodium fluoride Approved Phase 1, Phase 2 7681-49-4
121
Misoprostol Approved Phase 2 59122-46-2 5282381
122
leucovorin Approved Phase 2 58-05-9 6006 143
123
Pemetrexed Approved, Investigational Phase 2 150399-23-8, 137281-23-3 446556 60843
124
Nicotine Approved Phase 1, Phase 2 54-11-5 942 89594
125
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
126
Ketorolac Approved Phase 2 74103-06-3, 66635-83-4 3826
127
Silicon Approved, Investigational Phase 2 7440-21-3 4082203
128
Ethanol Approved Phase 2 64-17-5 702
129
Ergocalciferol Approved, Nutraceutical Phase 2 50-14-6 5280793
130
Vitamin D Approved, Nutraceutical, Vet_approved Phase 2 1406-16-2
131
Vitamin A Approved, Nutraceutical, Vet_approved Phase 2 68-26-8, 11103-57-4, 22737-96-8 445354 9904001
132 Fluorides Phase 1, Phase 2
133 Listerine Phase 1, Phase 2
134 Cariostatic Agents Phase 1, Phase 2
135 Gastrointestinal Agents Phase 2
136 Anti-Ulcer Agents Phase 2
137 Antacids Phase 2
138 Oxytocics Phase 2
139 Dermatologic Agents Phase 2
140 Folic Acid Antagonists Phase 2
141 Chlorhexidine gluconate Phase 2
142 Anti-Infective Agents, Local Phase 2
143 Ergocalciferols Phase 2
144 Vitamin D2 Phase 2
145 Calciferol Phase 2
146 Nicotinic Agonists Phase 1, Phase 2
147 Photosensitizing Agents Phase 2
148 Hormone Antagonists Phase 2
149 Sodium Channel Blockers Phase 2
150 Ketorolac Tromethamine Phase 2
151 Diuretics, Potassium Sparing Phase 2
152 Hypoglycemic Agents Phase 2
153 Incretins Phase 2
154 Dipeptidyl-Peptidase IV Inhibitors Phase 2
155 Sitagliptin Phosphate Phase 2
156 Propolis Phase 2
157 retinol Phase 2
158 Locust bean gum Phase 2
159 Antiviral Agents Phase 2
160 Retinol palmitate Phase 2
161 Bee Products Phase 2
162
Bismuth Phase 2 7440-69-9 16682734 105143
163
Dexmedetomidine Approved, Vet_approved Phase 1 113775-47-6 68602 5311068
164 Adrenergic Agents Phase 1
165 Analgesics, Non-Narcotic Phase 1
166 Analgesics Phase 1
167 Anesthetics Phase 1
168 Hypnotics and Sedatives Phase 1
169 Salicylsalicylic acid Phase 1
170 Salicylates Phase 1
171 Sodium salicylate Phase 1 54-21-7
172 Adrenergic alpha-2 Receptor Agonists Phase 1
173 Antibodies, Monoclonal Phase 1
174 Antineoplastic Agents, Immunological Phase 1
175 Immunoglobulins Phase 1
176 Antibodies Phase 1
177
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757
178
Polyestradiol phosphate Approved 28014-46-2
179
Diclofenac Approved, Vet_approved 15307-86-5 3033
180
Celecoxib Approved, Investigational Early Phase 1 169590-42-5 2662
181
acetic acid Approved 64-19-7 176
182
tannic acid Approved 1401-55-4
183
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
184
Methylene blue Approved, Investigational 61-73-4
185
Minocycline Approved, Investigational Early Phase 1 10118-90-8 5281021
186
Formaldehyde Approved, Vet_approved 50-00-0 712
187
Calcium carbonate Approved, Investigational 471-34-1