MCID: HRY002
MIFTS: 28

Hairy Tongue

Categories: Oral diseases, Rare diseases, Smell/Taste diseases

Aliases & Classifications for Hairy Tongue

MalaCards integrated aliases for Hairy Tongue:

Name: Hairy Tongue 12 73 20 15 17 70
Black Hairy Tongue 20 70
Overgrowth of Filiform Papillae 12
Lingua Villosa 20
Tongue, Hairy 44

Classifications:



External Ids:

Disease Ontology 12 DOID:13500
MeSH 44 D014064
NCIt 50 C35075
SNOMED-CT 67 81934005
UMLS 70 C0040414 C0235347

Summaries for Hairy Tongue

GARD : 20 Black hairy tongue is a relatively common condition in which the the central top portion of the tongue presents with an abnormal coloring and coating. Although the abnormal coating is typically black in color, brown, yellow, and green discoloration have been described. Individuals with black hairy tongue usually do not have symptoms, although occasionally there may be a burning, gagging, or tickling sensation. Halitosis (bad breath) or abnormal taste may additionally be present. Black hairy tongue can occur at any age, but the incidence increases with age. Black hairy tongue occurs due to a lack of stimulation on the top of the tongue resulting in a buildup of a protein known as keratin. This buildup can become quite long, giving it a hair-like appearance. Though black hairy tongue can present at any point, certain factors increase one's risk, such as poor oral hygiene, use of medications (particularly antibiotics ), tobacco use, therapeutic radiation, and certain illnesses. Treatment varies depending on complexity; however, many cases can easily be resolved with brushing the tongue with a toothbrush or using a tongue scraper.

MalaCards based summary : Hairy Tongue, also known as black hairy tongue, is related to geographic tongue and glossitis, and has symptoms including glossalgia An important gene associated with Hairy Tongue is KRT4 (Keratin 4), and among its related pathways/superpathways are S-1P Stimulated Signaling and Yersinia infection. Affiliated tissues include tongue and skin.

Wikipedia : 73 Black hairy tongue syndrome (BHT) is a condition of the tongue in which the small bumps on the tongue... more...

Related Diseases for Hairy Tongue

Diseases related to Hairy Tongue via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 geographic tongue 10.2
2 glossitis 10.2
3 leukoplakia 10.2
4 dysphagia 10.1
5 trigeminal neuralgia 10.1
6 oral hairy leukoplakia 10.1
7 fissured tongue 10.1
8 median rhomboid glossitis 10.1
9 osteomyelitis 10.0
10 keratosis 10.0
11 acanthosis nigricans 9.9
12 amyotrophic lateral sclerosis 1 9.9
13 major affective disorder 1 9.9
14 ige responsiveness, atopic 9.9
15 temporal arteritis 9.9
16 prostatic hyperplasia, benign 9.9
17 severe cutaneous adverse reaction 9.9
18 major affective disorder 8 9.9
19 major affective disorder 9 9.9
20 graft-versus-host disease 9.9
21 erythema multiforme 9.9
22 exanthem 9.9
23 tongue disease 9.9
24 prostatic hypertrophy 9.9
25 diarrhea 9.9
26 central neurocytoma 9.9
27 oral candidiasis 9.9
28 hepatitis c 9.9
29 pharyngitis 9.9
30 lateral sclerosis 9.9
31 prostatic adenoma 9.9
32 pulmonary tuberculosis 9.9
33 substance abuse 9.9
34 bipolar disorder 9.9
35 burning mouth syndrome 9.9
36 pustulosis of palm and sole 9.9
37 lymphopenia 9.9
38 end stage renal disease 9.9
39 psoriasis 9.9
40 priapism 9.9
41 stomatitis 9.9
42 oral leukoplakia 9.9
43 posttransplant acute limbic encephalitis 9.9
44 erythema multiforme major 9.9
45 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.9
46 overgrowth syndrome 9.9
47 xerophthalmia 9.6 CD4 CA6
48 lacrimal apparatus disease 9.5 CD4 CA6
49 potocki-shaffer syndrome 9.4 CD4 CA6

Graphical network of the top 20 diseases related to Hairy Tongue:



Diseases related to Hairy Tongue

Symptoms & Phenotypes for Hairy Tongue

UMLS symptoms related to Hairy Tongue:


glossalgia

Drugs & Therapeutics for Hairy Tongue

Search Clinical Trials , NIH Clinical Center for Hairy Tongue

Cochrane evidence based reviews: tongue, hairy

Genetic Tests for Hairy Tongue

Anatomical Context for Hairy Tongue

MalaCards organs/tissues related to Hairy Tongue:

40
Tongue, Skin

Publications for Hairy Tongue

Articles related to Hairy Tongue:

(show top 50) (show all 186)
# Title Authors PMID Year
1
How honey bees dip nectar: Dynamic spacing of tongue hairs facilitates to collect nectar of various viscosities. 61
33189760 2021
2
A Case of Lingua Villosa Nigra (Black Hairy Tongue) in a 3-Month-Old Infant. 61
33361746 2020
3
Black hairy tongue in an end-stage renal disease patient. 61
33388236 2020
4
Antibiotic-induced black hairy tongue: two case reports and a review of the literature. 61
33044871 2020
5
Drinking made easier: honey bee tongues dip faster into warmer and/or less viscous artificial nectar. 61
32737214 2020
6
Feeding behavior of honey bees on dry sugar. 61
32446764 2020
7
Tetracycline-induced black hairy tongue. 61
32489761 2020
8
Glycopyrrolate-Induced Black Hairy Tongue. 61
32477994 2020
9
Temporal model of fluid-feeding mechanisms in a long proboscid orchid bee compared to the short proboscid honey bee. 61
31542476 2020
10
Adverse reaction report and retrospective analysis of black hairy tongue caused by linezolid. 61
32944496 2020
11
Oral Manifestations in HIV-TB Co- infected Patients and Their Correlation with CD4 Count in Telangana State, India. 61
32181218 2020
12
Effects of Electronic Cigarettes on Oral Cavity: A Systematic Review. 61
31843181 2019
13
Global Prevalence of Tobacco Use in Adolescents and Its Adverse Oral Health Consequences. 61
32010395 2019
14
Image Gallery: Black hairy tongue in a patient receiving enteral feeding. 61
31297789 2019
15
Prednisolone-Induced Hairy Tongue: A Case Report. 61
31598603 2019
16
A review and guide to drug-associated oral adverse effects-Dental, salivary and neurosensory reactions. Part 1. 61
31192500 2019
17
Black hairy tongue: clinical management. 61
31347813 2019
18
Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management. 61
31090139 2019
19
Non-HPV Papillary Lesions of the Oral Mucosa: Clinical and Histopathologic Features of Reactive and Neoplastic Conditions. 61
30693457 2019
20
Hairy Tongue: Differential Diagnosis by Use of Widefield Optical Fluorescence. 61
30970064 2019
21
Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa. 61
30671761 2019
22
Hairy tongue in a 1-month-old infant. 61
29363492 2019
23
Linezolid-induced black hairy tongue. 61
30333468 2018
24
Oral pigmentation in physiologic conditions, post-inflammatory affections and systemic diseases. 61
28421728 2018
25
Black Hairy Tongue. 61
30184449 2018
26
Oral mucosal lesions in electronic cigarettes consumers versus former smokers. 61
29161938 2018
27
Prevalence and Distribution of Oral Mucosal Lesions by Sex and Age Categories: A Retrospective Study of Patients Attending Lebanese School of Dentistry. 61
29887889 2018
28
The yellow hairy tongue. 61
30637082 2018
29
Black Hairy Tongue. 61
28573500 2017
30
Black hairy tongue. 61
28162220 2017
31
Global health challenges in treating an elderly institutionalised patient: an oral medicine perspective. 61
29103008 2017
32
Black Hairy Tongue: Predisposing Factors, Diagnosis, and Treatment. 61
28247090 2017
33
Black hairy tongue cured concurrently with respiratory infection. 61
28628432 2017
34
Black hairy tongue with olanzapine: A rare case report. 61
28827881 2017
35
Black Hairy Tongue Associated With Lorazepam Treatment of a Male Smoker With Major Depression. 61
28129309 2017
36
Black brown discoloration and hairy tongue - A rare linezolid side effect. 61
28166916 2017
37
Black hairy tongue after chemotherapy for malignant brain tumors. 61
27878617 2017
38
Black hairy tongue (Lingua villosa nigra) in a young male precipitated by Lithium. 61
27931913 2016
39
Linezolide-induced hairy tongue. 61
28031852 2016
40
Prevalence and distribution of oral mucosal non-malignant lesions in the western Sicilian population. 61
27374359 2016
41
Diseases of the tongue. 61
27343960 2016
42
Black hairy tongue with a fixed dose combination of olanzapine and fluoxetine. 61
27298505 2016
43
Prevalence of oro-dental anomalies among schoolchildren in Sana'a city, Yemen. 61
27117648 2016
44
Black hairy tongue in a patient with amyotrophic lateral sclerosis. 61
27011938 2016
45
[An infant with a black hairy tongue]. 61
27229695 2016
46
[The impact of tobacco on oral health - based on literature]. 61
29677424 2016
47
Black hairy tongue during interferon therapy for hepatitis C. 61
25864223 2015
48
Oral mucosal lesions in elderly dental patients in Sana'a, Yemen. 61
25984462 2015
49
High-Dose Loperamide Abuse Inducing Life-Threatening Cardiac Arrhythmias; Topiramate-Induced Diarrhea in a Breastfed Infant; Danazol-Induced Stevens-Johnson Syndrome; Asenapine-Induced Myasthenic Syndrome; Black Hairy Tongue Due to Linezolid; Adalimumab-Induced Priapism. 61
26405319 2015
50
Oral health status among Iranian veterans exposed to sulfur mustard: A case-control study. 61
26155331 2015

Variations for Hairy Tongue

Expression for Hairy Tongue

Search GEO for disease gene expression data for Hairy Tongue.

Pathways for Hairy Tongue

Pathways related to Hairy Tongue according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.94 RAC3 CD4
2 10.76 RAC3 CD4

GO Terms for Hairy Tongue

Biological processes related to Hairy Tongue according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 8.96 MIER1 CD4
2 neuromuscular process controlling balance GO:0050885 8.62 RAC3 GM2A

Sources for Hairy Tongue

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....