Aliases & Classifications for Hand Skill, Relative

MalaCards integrated aliases for Hand Skill, Relative:

Name: Hand Skill, Relative 56 13
Handedness 17
Hsr 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant vs. multifactorial


HPO:

31
hand skill, relative:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 139900
MedGen 41 C0023114
SNOMED-CT via HPO 68 263681008

Summaries for Hand Skill, Relative

MalaCards based summary : Hand Skill, Relative, also known as handedness, is related to ocular dominance and helix syndrome. An important gene associated with Hand Skill, Relative is HSR (Hand Skill, Relative). The drugs Caffeine and Phenelzine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and cortex.

More information from OMIM: 139900

Related Diseases for Hand Skill, Relative

Diseases related to Hand Skill, Relative via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 ocular dominance 11.8
2 helix syndrome 10.5
3 dyslexia 10.5
4 schizophrenia 10.5
5 neuroblastoma 10.4
6 autism 10.4
7 stuttering 10.4
8 leukemia, acute myeloid 10.3
9 migraine with or without aura 1 10.3
10 autoimmune disease 10.3
11 hair whorl 10.3
12 schizotypal personality disorder 10.3
13 aphasia 10.3
14 myelodysplastic syndrome 10.3
15 allergic hypersensitivity disease 10.3
16 myeloid leukemia 10.3
17 learning disability 10.2
18 alcohol dependence 10.2
19 anxiety 10.2
20 autism spectrum disorder 10.2
21 chromosomal triplication 10.2
22 ring chromosome 10.2
23 refractory anemia 10.2
24 breast cancer 10.2
25 strabismus 10.2
26 scoliosis 10.2
27 epilepsy 10.2
28 mechanical strabismus 10.2
29 dermatitis 10.2
30 situs inversus 10.2
31 osteoarthritis 10.2
32 cleft lip 10.2
33 tremor 10.2
34 attention deficit-hyperactivity disorder 10.1
35 major affective disorder 8 10.1
36 major affective disorder 9 10.1
37 speech and communication disorders 10.1
38 pedophilia 10.1
39 cerebral palsy 10.1
40 bipolar disorder 10.1
41 temporal lobe epilepsy 10.1
42 headache 10.1
43 cleft palate, isolated 10.1
44 apraxia 10.1
45 idiopathic scoliosis 10.1
46 personality disorder 10.1
47 developmental coordination disorder 10.1
48 developmental dyspraxia 10.1
49 cleft lip with or without cleft palate 10.1
50 colorectal cancer 10.0

Graphical network of the top 20 diseases related to Hand Skill, Relative:



Diseases related to Hand Skill, Relative

Symptoms & Phenotypes for Hand Skill, Relative

Symptoms via clinical synopsis from OMIM:

56
Misc:
handedness

Clinical features from OMIM:

139900

Drugs & Therapeutics for Hand Skill, Relative

Drugs for Hand Skill, Relative (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 142)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved Phase 4 58-08-2 2519
2
Phenelzine Approved Phase 4 51-71-8 3675
3
Citalopram Approved Phase 4 59729-33-8 2771
4
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
5
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
6
Fluvoxamine Approved, Investigational Phase 4 54739-18-3 3404 5324346
7
Doxepin Approved, Investigational Phase 4 1668-19-5 667477 667468
8
Amitriptyline Approved Phase 4 50-48-6 2160
9
Protriptyline Approved Phase 4 438-60-8 4976
10
Clomipramine Approved, Investigational, Vet_approved Phase 4 303-49-1 2801
11
Nortriptyline Approved Phase 4 72-69-5 4543
12
Pindolol Approved, Investigational Phase 4 13523-86-9 4828
13
Clozapine Approved Phase 4 5786-21-0 2818
14
Imipramine Approved Phase 4 50-49-7 3696
15
Desipramine Approved, Investigational Phase 4 50-47-5 2995
16
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
17
Moclobemide Approved, Investigational Phase 4 71320-77-9 4235
18
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
19
Trimipramine Approved Phase 4 739-71-9 5584 4055
20
Sertraline Approved Phase 4 79617-96-2 68617
21
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
22
Topiramate Approved Phase 4 97240-79-4 5284627
23
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
24
Pramipexole Approved, Investigational Phase 4 104632-26-0 119570 59868
25
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
26
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
27
Isocarboxazid Approved Phase 4 59-63-2 3759
28
Lithium carbonate Approved Phase 4 554-13-2
29
Maprotiline Approved, Investigational Phase 4 10262-69-8 4011
30
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
31
Ziprasidone Approved Phase 4 146939-27-7 60854
32
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
33
Budesonide Approved Phase 4 51333-22-3 63006 5281004
34
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
35
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
36
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
37
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
38
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
39 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
40
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
41
Taurine Approved, Nutraceutical Phase 4 107-35-7 1123
42
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
43 Sodium Channel Blockers Phase 4
44 Diuretics, Potassium Sparing Phase 4
45 Venlafaxine Hydrochloride Phase 4
46 Amitriptyline, perphenazine drug combination Phase 4
47 Atomoxetine Hydrochloride Phase 4
48 Hormone Antagonists Phase 4
49 Hormones Phase 4
50 Antineoplastic Agents, Hormonal Phase 4

Interventional clinical trials:

(show top 50) (show all 114)
# Name Status NCT ID Phase Drugs
1 Transcranial Direct Current Stimulation (TDCS) as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy - Active and Placebo Controlled Double Blind Study Unknown status NCT01729507 Phase 4
2 The Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students Completed NCT02535143 Phase 4 Taurine
3 A Randomized Clinical Trial of Cutaneous Xylocaine Spray to Reduce Intravenous Cannulation Pain in Adults Completed NCT02562144 Phase 4 Xylocaine spray;Placebo
4 Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism Completed NCT00704860 Phase 4
5 Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses Completed NCT02219438 Phase 4 ropivacaine
6 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device: A Randomized, Single-blind, Parallel Trial Comparing the Lying-Head-Back Versus the Head-Down-to-Floor Positions Completed NCT02079792 Phase 4
7 The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint: A Randomized Control Trial Not yet recruiting NCT04177433 Phase 4 Depo-Medrol Injectable Product;Saline
8 A Randomized, Double-blind Controlled Trial of Bupivacaine Extended-release Liposome Injection for Postsurgical Analgesia in Patients Undergoing Open-reduction Internal Fixation of the Distal Radius Terminated NCT02515851 Phase 4 Exparel;Placebo
9 The Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy Withdrawn NCT03711097 Phase 4 Vanish XT Dental Varnish
10 A Prospective, Randomized, Open-label, Multicenter Study Evaluating the Effects on Cognitive Functions of Adjuvant Endocrine Therapy in Postmenopausal Women With Breast Cancer. Unknown status NCT00893061 Phase 3 anastrozole;exemestane;letrozole;tamoxifen citrate
11 Metformin in Alzheimer's Dementia Prevention Not yet recruiting NCT04098666 Phase 2, Phase 3 Placebo oral tablet;extended release metformin
12 Basis for an Etiological Diagnosis and Treatment of the Chronic TMD-pain: RCT Study Completed NCT00899717 Phase 1, Phase 2
13 Stroke Inpatient Rehabilitation Reinforcement of Walking Speed Completed NCT00428480 Phase 1
14 N-Acetylcysteine in the Treatment of Deliberate Self-Harm in Adolescents: An Open Label Pilot Study Completed NCT01111734 Phase 1 fMRI
15 OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DELAY AND DEAFNESS: A PROSPECTIVE, RANDOMIZED TRIAL Completed NCT01256229 Phase 1
16 Changes in Brain Synchronization During Perceptual and Linguistic Tasks in Schizophrenic Patients Unknown status NCT01550211
17 Comparison of Two Radial Artery Segments Related to "Old-Fashioned" Radial and New Snuff Box Vessel Approach. Ultrasound Study of Both Arms Unknown status NCT03486470
18 Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder: a Follow-up Study Unknown status NCT02233348
19 Gestural Short Term and Working Memory Task Unknown status NCT02859649
20 Does Standardizing Language in Laparoscopic Surgery Improve Efficiency? A Randomized Controlled Trial Unknown status NCT02565875
21 Structural and Functional Connectivity in Autism Spectrum Disorders by Using Diffusion Spectrum Imaging and Functional Magnetic Resonance Imaging Studies Unknown status NCT00755430
22 Neuropsychology, Neuroimage and Neurophysiology in Adults With Attention-Deficit Hyperactivity Disorder: An Endophenotype and Follow-up Study Unknown status NCT02642068
23 Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders Unknown status NCT01513629
24 Examining the Neural Bases of Early Visual and Auditory Processing and Emotion Recognition Deficits in Schizophrenia Using Magnetoencephalography Unknown status NCT02588014
25 Adult Outcome of Children With Attention-deficit/Hyperactivity Disorder Unknown status NCT01247610
26 Neuropsychopathological Study of Autism: From Clinical, Neurocognitive, to Genetic Studies and Animal Models Unknown status NCT01677663
27 A Randomized Study of Non-Operative Management Versus Expedited Surgery Among WCB Patients With Small Rotator Cuff Tears: Affect Upon Time to Claim Closure in 2 Prairie Provinces Unknown status NCT01498198
28 Type II Pediatric Supracondylar Humerus Fracture Management and Outcomes: A Prospective Multi-centre Cohort Study Unknown status NCT02963233
29 Freehand Ultrasound to Evaluate Scapular Kinematics in People With Paraplegia Unknown status NCT02357914
30 The Use of Transcranial Electrical Stimulation for Hallucinations Unknown status NCT02715765
31 Mapping the Genetic Component of Hand-Use Preference Completed NCT00005003
32 Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects Completed NCT02523742
33 Knowing and Remembering: Cognitive and Neural Influences of Familiarity on Recognition Memory in Early Alzheimer's Disease Completed NCT02492529
34 Validity and Reliability of an Activity Monitor in Persons With a Cerebrovascular Accident Completed NCT00849446
35 Volumetric Brain MRI (Magnetic Resonance Imaging) Comparison of Patients With Treatment Resistant Depression (TRD) Undergoing Deep Brain Stimulation (DBS) With Age, Sex and Education Matched Healthy Controls Completed NCT01162434
36 Asymmetry, Auditory Processing and Reading Skills in Phonological Dyslexic Children Compared to Average-reading Children Completed NCT02345876
37 Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease Completed NCT03580486
38 Neuromodulation With rTMS in Dysphagic Patients With Stroke Completed NCT02893033
39 Validating a New Writer's Cramp Scale Completed NCT01579266
40 Anatomical and Functional MRI Study of Episodic Memory in Epileptic Compared to Normal Children Completed NCT00242905
41 Investigation of the Effects of Independent Transfer Training Completed NCT03160612
42 Measurement of Induced Strains in the Human Tibia During Vibration Therapy and Habitual Activities Completed NCT01430858
43 Test-retest Reliability of Measuring the Area and Intensity of Secondary Hyperalgesia Induced by High Frequency Stimulation of Skin Nociceptors Completed NCT03966508
44 Motor Memory: Study of the Role of Dopamine in Healthy Subjects and Patients With Parkinson's Disease Using PET and EEG Completed NCT00032812 Raclopride
45 Anthropogenetic Variability in the Group of Individuals With Febrile Seizures - Population Genetic Study Completed NCT03481764
46 Comparison of Anti-craving Efficacy of Right and Left Prefrontal High Frequency rTMS in Alcohol Dependence: a Randomized Double-blind Study Completed NCT01093716
47 Functional Connectivity of the Basal Ganglia in Primary Focal Dystonia Completed NCT01761903
48 The Role of the Prefrontal Cortex in Economic Decision-Making in Reciprocal Trust Games Using Functional Hyperscanning Neuroimaging Completed NCT00083317
49 FEATHERS 2.0: Functional Engagement in Assistive Therapy Through Exercise Robotics v2.0 Completed NCT03766711
50 Deliberate Practice With Validated Metrics Improves Skill Acquisition in Performance of Ultrasound Guided Peripheral Nerve Block in a Simulated Setting Completed NCT03154372

Search NIH Clinical Center for Hand Skill, Relative

Genetic Tests for Hand Skill, Relative

Anatomical Context for Hand Skill, Relative

MalaCards organs/tissues related to Hand Skill, Relative:

40
Brain, Testes, Cortex, Eye, Temporal Lobe, Breast, Bone

Publications for Hand Skill, Relative

Articles related to Hand Skill, Relative:

(show top 50) (show all 6978)
# Title Authors PMID Year
1
Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11. 61 56
14583442 2003
2
Human handedness and scalp hair-whorl direction develop from a common genetic mechanism. 56 61
14504234 2003
3
Parametric and non-parametric linkage analysis of several candidate regions for genes for human handedness. 56 61
12357333 2002
4
Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. 61 56
11867730 2002
5
A genomewide linkage screen for relative hand skill in sibling pairs. 61 56
11774074 2002
6
Individual differences in handedness and specific speech and language impairment: evidence against a genetic link. 56 61
11720120 2001
7
A gene-culture model of human handedness. 61 56
7487840 1995
8
Handedness and life span. 56 61
2002827 1991
9
Left handedness is uncommon in breast cancer patients. 56 61
1782085 1991
10
Handedness in systemic lupus erythematosus. 61 56
3964317 1986
11
Left-handedness: association with immune disease, migraine, and developmental learning disorder. 56 61
6956919 1982
12
Family handedness in three generations predicted by the right shift theory. 61 56
475335 1979
13
Laterality in twins: the relationship between handedness and hemispheric asymmetry for speech. 61 56
567977 1978
14
Genetic and nongenetic influences on handedness. 61 56
687316 1978
15
Fifty centuries of right-handedness: the historical record. 61 56
335510 1977
16
Concerning the origin of handedness in humans. 56 61
843315 1977
17
A review of evidence for a genetic component in the determination of handedness. 56 61
791243 1976
18
Human handedness: a partial cross-fostering study. 56 61
1273577 1976
19
Preferences for handedness, arm folding, and hand clasping in families. 56 61
4461659 1974
20
Handedness in families. 61 56
4759906 1973
21
A model for the genetics of handedness. 56 61
5073852 1972
22
A MODEL OF THE INHERITANCE OF HANDEDNESS AND CEREBRAL DOMINANCE. 61 56
14240116 1964
23
Handedness, with Special Reference to Twins. 61 56
17246963 1940
24
Confirmatory evidence for linkage of relative hand skill to 2p12-q11. 56
12596796 2003
25
A single locus, RGHT, specifies preference for hand utilization in humans. 56
9246435 1996
26
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. 56
7581446 1995
27
Do right-handers live longer? 56
3367996 1988
28
Identification and sorting of particle chirality using liquid crystallinity. 61
32298977 2020
29
Dynamic tractography: Integrating cortico-cortical evoked potentials and diffusion imaging. 61
32294537 2020
30
A strong correlation between consensus sequences and unique super secondary structures in leucine rich repeats. 61
31998983 2020
31
Measuring infant handedness reliably from reaching: A systematic review. 61
32063179 2020
32
Right-handed one day, right-handed the next day? 61
32066321 2020
33
Why are consistently-handed individuals more authoritarian? The role of need for cognitive closure. 61
32498598 2020
34
Genetic localization of the SPC gene controlling pod coiling direction in Medicago truncatula. 61
32449065 2020
35
The effects of hemispheric dominance, literacy acquisition, and handedness on the development of visuospatial attention: A study in preschoolers and second graders. 61
32203730 2020
36
Enantioselective photoinduced cyclodimerization of a prochiral anthracene derivative adsorbed on helical metal nanostructures. 61
32313237 2020
37
Chiral Assemblies of Laser-Printed Micropillars Directed by Asymmetrical Capillary Force. 61
32567083 2020
38
Crystallization-Driven Asymmetric Helical Assembly of Conjugated Block Copolymer and the Aggregation Induced White-light Emission and Circularly Polarized Luminescence. 61
32543000 2020
39
Modular Molecular Self-Assembly for Diversified Chiroptical Systems. 61
32578382 2020
40
Plasmonic Manipulation-Controlled Chiral Crystallization of Sodium Chlorate. 61
32401515 2020
41
Chiral Surface Lattice Resonances. 61
32319171 2020
42
Silicon microprotrusions with tailored chirality enabled by direct femtosecond laser ablation. 61
32479456 2020
43
Carrying human infants - An evolutionary heritage. 61
32569907 2020
44
Helical Magnetic Field-Induced Real-Time Plasmonic Chirality Modulation. 61
32298072 2020
45
Chirality from Cryo-Electron Tomograms of Nanocrystals Obtained by Lateral Disassembly and Surface Etching of Never-Dried Chitin. 61
32426968 2020
46
Long-term Pingju Opera Training Induces Plasticity Changes in Cerebral Blood Flow: An Arterial Spin Labelling MRI Study. 61
32283180 2020
47
Photoprogrammable Mesogenic Soft Helical Architectures: A Promising Avenue toward Future Chiro-Optics. 61
32483915 2020
48
The dominant limb preferentially stabilizes posture in a bimanual task with physical coupling. 61
32348682 2020
49
A pilot study evaluating the effects of concussion on the ability to form cognitive maps for spatial orientation in adolescent hockey players. 61
32506963 2020
50
White-matter integrity and hearing acuity decline in healthy subjects: Magnetic resonance tractography. 61
32216576 2020

Variations for Hand Skill, Relative

Expression for Hand Skill, Relative

Search GEO for disease gene expression data for Hand Skill, Relative.

Pathways for Hand Skill, Relative

GO Terms for Hand Skill, Relative

Sources for Hand Skill, Relative

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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