Aliases & Classifications for Hand Skill, Relative

MalaCards integrated aliases for Hand Skill, Relative:

Name: Hand Skill, Relative 57 13
Hsr 57

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant vs. multifactorial


HPO:

32
hand skill, relative:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 57 139900
MedGen 42 C0023114
SNOMED-CT via HPO 69 263681008

Summaries for Hand Skill, Relative

MalaCards based summary : Hand Skill, Relative, also known as hsr, is related to neuroblastoma and leukemia, acute myeloid. An important gene associated with Hand Skill, Relative is HSR (Hand Skill, Relative). The drugs Caffeine and Imipramine have been mentioned in the context of this disorder. Affiliated tissues include myeloid, colon and testes.

Description from OMIM: 139900

Related Diseases for Hand Skill, Relative

Diseases related to Hand Skill, Relative via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 neuroblastoma 10.2
2 leukemia, acute myeloid 10.1
3 melanoma 10.1
4 myeloid leukemia 10.1
5 alzheimer disease 9.9
6 breast cancer 9.9
7 retinoblastoma 9.9
8 rheumatoid arthritis 9.9
9 premature centromere division 9.9
10 pancreatic cancer 9.9
11 aging 9.9
12 arthritis 9.9
13 leukemia 9.9

Graphical network of the top 20 diseases related to Hand Skill, Relative:



Diseases related to Hand Skill, Relative

Symptoms & Phenotypes for Hand Skill, Relative

Symptoms via clinical synopsis from OMIM:

57
Misc:
handedness


Clinical features from OMIM:

139900

Drugs & Therapeutics for Hand Skill, Relative

Drugs for Hand Skill, Relative (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 188)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved Phase 4 58-08-2 2519
2
Imipramine Approved Phase 4 50-49-7 3696
3
Dopamine Approved Phase 4,Not Applicable,Early Phase 1 51-61-6, 62-31-7 681
4
Bupropion Approved Phase 4,Early Phase 1 34841-39-9, 34911-55-2 444
5
Citalopram Approved Phase 4,Early Phase 1 59729-33-8 2771
6
Mirtazapine Approved Phase 4 61337-67-5, 85650-52-8 4205
7
Sertraline Approved Phase 4 79617-96-2 68617
8
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
9
Desipramine Approved, Investigational Phase 4 50-47-5 2995
10
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
11
Lithium carbonate Approved Phase 4 554-13-2
12
Maprotiline Approved, Investigational Phase 4 10262-69-8 4011
13
Doxepin Approved, Investigational Phase 4 1668-19-5 667477 667468
14
Pindolol Approved, Investigational Phase 4 13523-86-9 4828
15
Fluvoxamine Approved, Investigational Phase 4 54739-18-3 3404 5324346
16
Protriptyline Approved Phase 4 438-60-8 4976
17
Trimipramine Approved Phase 4 739-71-9 5584 4055
18
Ziprasidone Approved Phase 4 146939-27-7 60854
19
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
20
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
21
Moclobemide Approved, Investigational Phase 4 71320-77-9 4235
22
Amitriptyline Approved Phase 4 50-48-6 2160
23
Phenelzine Approved Phase 4 51-71-8 3675
24
Pramipexole Approved, Investigational Phase 4 104632-26-0 119570 59868
25
Isocarboxazid Approved Phase 4 59-63-2 3759
26
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
27
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
28
Clomipramine Approved, Investigational, Vet_approved Phase 4 303-49-1 2801
29
Clozapine Approved Phase 4 5786-21-0 2818
30
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
31
Nortriptyline Approved Phase 4 72-69-5 4543
32
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
33
Topiramate Approved Phase 4 97240-79-4 5284627
34
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
35
Taurine Approved, Nutraceutical Phase 4 107-35-7 1123
36 Antidepressive Agents Phase 4,Not Applicable,Early Phase 1
37 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
38 Antiparkinson Agents Phase 4,Not Applicable,Early Phase 1
39 Parasympatholytics Phase 4,Early Phase 1
40 Cholinergic Agents Phase 4,Phase 3,Early Phase 1
41 Psychotropic Drugs Phase 4,Not Applicable,Early Phase 1
42 Neurotransmitter Uptake Inhibitors Phase 4,Not Applicable,Early Phase 1
43 Cholinergic Antagonists Phase 4,Not Applicable,Early Phase 1
44 Antidepressive Agents, Tricyclic Phase 4
45 Cytochrome P-450 Enzyme Inhibitors Phase 4,Early Phase 1
46 Antidepressive Agents, Second-Generation Phase 4,Not Applicable,Early Phase 1
47 Muscarinic Antagonists Phase 4,Early Phase 1
48 Dopamine Uptake Inhibitors Phase 4,Early Phase 1
49 Serotonin Uptake Inhibitors Phase 4,Early Phase 1
50 Serotonin Agents Phase 4,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 176)
# Name Status NCT ID Phase Drugs
1 Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students Completed NCT02535143 Phase 4 Taurine
2 Dichotic Listening as a Predictor of Medication Response in Depression Completed NCT00404755 Phase 4 escitalopram;bupropion;imipramine
3 The Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy Not yet recruiting NCT03711097 Phase 4 Vanish XT Dental Varnish
4 Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism Completed NCT00704860 Phase 4
5 Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder Completed NCT01831622 Phase 4 Ritalin;Placebo
6 Treatment of Depression Following Multiple Brain Tests Completed NCT00296777 Phase 4 Escitalopram;Bupropion;Imipramine
7 Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients Unknown status NCT02241213 Phase 3
8 Study of Botulinum Toxin and Recovery of Hand Function After Stroke Completed NCT01422161 Phase 3 Botulinum Toxin commonly known as BOTOX®
9 Effectiveness Study on a Virtual Reality Based Training System for Stroke Patients Completed NCT01774669 Phase 3
10 Stimulation for Perinatal Stroke Optimizing Recovery Trajectories Recruiting NCT03216837 Phase 2, Phase 3
11 Influence of Manual Therapy in Temporomandibular Joint Disorder Unknown status NCT02880774 Phase 1, Phase 2
12 Basic and Balance: Logan Basic Technique on Bilateral Weight Balance Completed NCT00740688 Phase 2
13 A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis Completed NCT03122860 Phase 2 SM04690;placebo
14 Peripheral Modulation of Muscle Stiffness and Spasticity Not yet recruiting NCT03306615 Phase 2 Hyaluronidase;Placebo
15 The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients Terminated NCT03173365 Phase 2 Brimonidine Tartrate
16 Treating Intention In Aphasia: Neuroplastic Substrates Completed NCT00567242 Phase 1, Phase 2
17 Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery Recruiting NCT03106038 Phase 1, Phase 2 Investigational Imaging Agent
18 Occlusal Adjustment as Treatment for Chronic Orofacial Pain Completed NCT00899717 Phase 1, Phase 2
19 A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis Active, not recruiting NCT01954693 Phase 2 Placebo;Everolimus (RAD001)
20 Enhancing Motor Plasticity After Perinatal Stroke Using tDCS Completed NCT02170285 Phase 2
21 Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy Suspended NCT02531880 Phase 1 Mangafodipir
22 Ankle Tracking Training in Stroke Completed NCT01298583 Phase 1
23 Movement Velocity Effect on Cortical Reorganization and Finger Function in Stroke Completed NCT01575366 Phase 1
24 Omega 3 Fatty Acid Trial Completed NCT00586222 Phase 1
25 Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living Completed NCT00878085 Phase 1
26 Neuropsychomotor Functions in Children With Autism Spectrum Disorder Unknown status NCT01987037
27 The Incidence of Perioperative Deep Venous Thromboses of the Lower Extremities Unknown status NCT01300832 Not Applicable
28 Changes in Brain Synchronization During Perceptual and Linguistic Tasks in Schizophrenic Patients Unknown status NCT01550211
29 Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor Unknown status NCT02428972 Not Applicable Propofol;Sevoflurane
30 Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders Unknown status NCT01513629
31 Interest Balance Auto-immune Population in Patients With Focal Epilepsy of Unknown Cause, Not Structural, Not Genetics, Newly Diagnosed Unknown status NCT02885207 Not Applicable
32 Does Vibration Therapy Induce Higher Than Normal Bone Strains and Strain Rates Than Those Experienced During Habitual Daily Activities Unknown status NCT01430858 Not Applicable
33 Graded Motor Imagery for Patients Within a Year After Stroke. Unknown status NCT01993563 Not Applicable
34 Pain Modulation in Rheumatoid Arthritis (RA) - Influence of Adalimumab Unknown status NCT01197144 Not Applicable adalimumab;Placebo
35 Hemiparetic Arm Robotic Mobilization With Non Invasive Electrical Stimulation Unknown status NCT03026712 Not Applicable
36 Survey of Patients With Idiopathic Orbital Inflammation Syndrome Unknown status NCT01443000
37 Causes of Visual Loss in Retinal Disease Unknown status NCT01613963 Immunosuppressive Agents
38 Workers Compensation Board: Rotator Cuff Tear Management Unknown status NCT01498198 Not Applicable
39 Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality Recruiting NCT03567109
40 Chewing Side Preference and Hemispheric Laterality in Healthy Adults Completed NCT03054246 Not Applicable
41 Imaging Laterality in Chronic Stroke Patients Recruiting NCT03584425 Early Phase 1
42 Genetic Component of Handedness Completed NCT00005003
43 Cerebral Microembolism During Hemodialysis Completed NCT02021045
44 Motor Imagery Ability After Stroke Not yet recruiting NCT03661073 Not Applicable
45 Comparative Analysis of Filmed Sequences for the Assessment of Discomfort in Atopic Dermatitis of Infants Under 6 Months of Age Not yet recruiting NCT03684343 Not Applicable
46 Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects Completed NCT02523742 Not Applicable
47 Brain MRI (Magnetic Resonance Imaging) Scans of Patients With Treatment Resistant Depression (TRD) and Healthy Controls Completed NCT01162434
48 Upper-limb Active Function and Botulinum Toxin A Not yet recruiting NCT03783572 Not Applicable
49 Non-genetic Risk Factors of Congenital Cataracts Recruiting NCT03215186
50 Multifocal Contact Lenses vs Bifocal Spectacles for Congenital Cataracts Active, not recruiting NCT03260764 Not Applicable

Search NIH Clinical Center for Hand Skill, Relative

Genetic Tests for Hand Skill, Relative

Anatomical Context for Hand Skill, Relative

MalaCards organs/tissues related to Hand Skill, Relative:

41
Myeloid, Colon, Testes, Lung, Brain, Uterus

Publications for Hand Skill, Relative

Articles related to Hand Skill, Relative:

(show top 50) (show all 116)
# Title Authors Year
1
HSR Begins a New Era. ( 29370590 )
2018
2
The impact of Fruit-Vegetable Diet on High Signal Resolution Pulse Wave (HSR-PW) Parameters. ( 29484356 )
2018
3
The expression of hSR-B1 receptor on platelets of patients with coronary artery disease (CAD). ( 29865042 )
2018
4
Evaluation of Alignment between the Health Claims Nutrient Profiling Scoring Criterion (NPSC) and the Health Star Rating (HSR) Nutrient Profiling Models. ( 30103402 )
2018
5
HSR Commentary: Linking VA and Non-VA Data to Address Important US Veteran Health Services Research Issues. ( 30430570 )
2018
6
Concomitant amplification of the MLL gene on a ring chromosome and a homogeneously staining region (hsr) in acute myeloid leukemia: mechanistic implications. ( 27733077 )
2017
7
Fifty Years of the Journal HSR: Informing Policy and Practice. ( 28543315 )
2017
8
Five Decades of HSR-By Words and Figures. ( 28543317 )
2017
9
Circuity analyses of HSR network and high-speed train paths in China. ( 28945757 )
2017
10
Theoretical insight into the heat shock response (HSR) regulation in Lactobacillus casei and L. rhamnosus. ( 27142777 )
2016
11
Fuzzy MUAP recognition in HSR-EMG detection basing on morphological features. ( 24875462 )
2014
12
c-MYC Amplification in Acute Myelogenous Leukemia Evolving from Double Minutes (dmins) to Homogeneously Staining Region (hsr). ( 26029796 )
2014
13
Imperatives for HSR addressing: Individuals with disabilities--the canaries in health care's coal mine. ( 23254696 )
2013
14
The FENO-HSR study: details of statistical analyses. ( 23734289 )
2013
15
Expansion of corticomedullary junction high-susceptibility region (CMJ-HSR) with aging: a clue in the pathogenesis of Alzheimer's disease? ( 21699603 )
2012
16
HSR editorial: oversimplifying health reform discussions. ( 22568651 )
2012
17
Field studies on the relation between the accumulation of heavy metals and metabolic and HSR in the bearded horse mussel Modiolus barbatus. ( 20937411 )
2011
18
Transcripts from the Drosophila heat-shock gene hsr-omega influence rates of protein synthesis but hardly affect resistance to heat knockdown. ( 21399957 )
2011
19
Differential expression of small heat shock protein genes Hsp23 and Hsp40, and heat shock gene Hsr-omega in fruit flies (Drosophila melanogaster) along a microclimatic gradient. ( 21505045 )
2011
20
Expert Panel recommendations--based on research and deliberations from VA HSR&D project "impact of the DOD paradigm shift on VA amputee prosthetic care". ( 20803398 )
2010
21
Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells. ( 20846458 )
2010
22
Fenoldopam to prevent renal replacement therapy after cardiac surgery. Design of the FENO-HSR study. ( 23440680 )
2010
23
Protein synthesis rates in Drosophila associate with levels of the hsr-omega nuclear transcript. ( 19280368 )
2009
24
Variant hypersensitivity reaction (HSR) presented with persistent dry cough after receiving oxaliplatin in a pancreatic cancer patient. ( 20124609 )
2009
25
Latitudinal and cold-tolerance variation associate with DNA repeat-number variation in the hsr-omega RNA gene of Drosophila melanogaster. ( 18560441 )
2008
26
Concurrent MYC and MLL amplification on dmin and hsr in acute myeloid leukemia. ( 18798113 )
2008
27
Variability of the chromosome 1 HSR of "Asian" type in the wild mouse (Mus musculus). ( 17515039 )
2007
28
Double minutes (dmin) and homogeneously staining regions (hsr) in myeloid disorders: a new case suggesting that dmin form hsr in vivo. ( 18160782 )
2007
29
An exercise in fatuity: research governance and the emasculation of HSR. ( 17018190 )
2006
30
Human sat III and Drosophila hsr omega transcripts: a common paradigm for regulation of nuclear RNA processing in stressed cells. ( 17020918 )
2006
31
When, where and how the bridge breaks: anaphase bridge breakage plays a crucial role in gene amplification and HSR generation. ( 15561104 )
2005
32
From the editors: external peer review at HSR. ( 15333106 )
2004
33
Cryptic ins(2;11) with clonal evolution showing amplification of 11q23-q25 either on hsr(11) or on dmin, in a patient with AML-M2. ( 15483676 )
2004
34
Thermal tolerance trade-offs associated with the right arm of chromosome 3 and marked by the hsr-omega gene in Drosophila melanogaster. ( 12634827 )
2003
35
Protonation equilibrium and lipophilicity of olamufloxacin (HSR-903), a newly synthesized fluoroquinolone antibacterial. ( 12957636 )
2003
36
In vitro and in vivo activity of olamufloxacin (HSR-903) against Legionella spp. ( 14613952 )
2003
37
Hypersensitivity reaction (HSR) to docetaxel after a previous HSR to paclitaxel. ( 12039945 )
2002
38
Induction of multiple double-strand breaks within an hsr by meganucleaseI-SceI expression or fragile site activation leads to formation of double minutes and other chromosomal rearrangements. ( 12400009 )
2002
39
Developmental regulation and complex organization of the promoter of the non-coding hsr(omega) gene of Drosophila melanogaster. ( 11255511 )
2001
40
Sequence and antigenic variability of the Helicobacter mustelae surface ring protein Hsr. ( 11292773 )
2001
41
The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice. ( 11418525 )
2001
42
An hsr on chromosome 7 was shown to be an insertion of four copies of the 11q23 MLL gene region in an HIV-related lymphoma. ( 11566339 )
2001
43
The RS-.HSR Hydrogen Bond: acidities of alpha,omega-dithiols and electron affinities of their monoradicals. ( 11583541 )
2001
44
Unusual chromosome architecture and behaviour at an HSR. ( 10929196 )
2000
45
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice. ( 10940779 )
2000
46
Omega speckles - a novel class of nuclear speckles containing hnRNPs associated with noncoding hsr-omega RNA in Drosophila. ( 10984439 )
2000
47
Effects of an amphoteric antiallergic agent, HSR-609, on antigen-induced late phase nasal eosinophilia in brown Norway rats. ( 11093074 )
2000
48
Carrier-mediated lung distribution of HSR-903, a new quinolone antibacterial agent. ( 10086990 )
1999
49
Effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum. ( 10348779 )
1999
50
Efflux transport of a new quinolone antibacterial agent, HSR-903, across the blood-brain barrier. ( 10381759 )
1999

Variations for Hand Skill, Relative

Expression for Hand Skill, Relative

Search GEO for disease gene expression data for Hand Skill, Relative.

Pathways for Hand Skill, Relative

GO Terms for Hand Skill, Relative

Sources for Hand Skill, Relative

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
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37 KEGG
38 LifeMap
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42 MedGen
44 MeSH
45 MESH via Orphanet
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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