Aliases & Classifications for Hand Skill, Relative

MalaCards integrated aliases for Hand Skill, Relative:

Name: Hand Skill, Relative 56 13
Handedness 17
Hsr 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant vs. multifactorial


HPO:

31
hand skill, relative:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 139900
MedGen 41 C0023114
SNOMED-CT via HPO 68 263681008

Summaries for Hand Skill, Relative

MalaCards based summary : Hand Skill, Relative, also known as handedness, is related to ocular dominance and helix syndrome. An important gene associated with Hand Skill, Relative is HSR (Hand Skill, Relative). The drugs Caffeine and Sertraline have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and cortex.

More information from OMIM: 139900

Related Diseases for Hand Skill, Relative

Diseases related to Hand Skill, Relative via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 ocular dominance 11.8
2 helix syndrome 10.5
3 dyslexia 10.5
4 schizophrenia 10.5
5 neuroblastoma 10.4
6 autism 10.4
7 stuttering 10.4
8 leukemia, acute myeloid 10.3
9 migraine with or without aura 1 10.3
10 autoimmune disease 10.3
11 hair whorl 10.3
12 schizotypal personality disorder 10.3
13 aphasia 10.3
14 myelodysplastic syndrome 10.3
15 allergic hypersensitivity disease 10.3
16 myeloid leukemia 10.3
17 learning disability 10.2
18 alcohol dependence 10.2
19 anxiety 10.2
20 autism spectrum disorder 10.2
21 chromosomal triplication 10.2
22 ring chromosome 10.2
23 refractory anemia 10.2
24 breast cancer 10.2
25 strabismus 10.2
26 scoliosis 10.2
27 epilepsy 10.2
28 mechanical strabismus 10.2
29 dermatitis 10.1
30 situs inversus 10.1
31 osteoarthritis 10.1
32 cleft lip 10.1
33 tremor 10.1
34 attention deficit-hyperactivity disorder 10.1
35 major affective disorder 8 10.1
36 major affective disorder 9 10.1
37 speech and communication disorders 10.1
38 pedophilia 10.1
39 bipolar disorder 10.1
40 temporal lobe epilepsy 10.1
41 headache 10.1
42 cleft palate, isolated 10.1
43 apraxia 10.1
44 idiopathic scoliosis 10.1
45 personality disorder 10.1
46 cerebral palsy 10.1
47 developmental coordination disorder 10.1
48 developmental dyspraxia 10.1
49 cleft lip with or without cleft palate 10.1
50 colorectal cancer 10.0

Graphical network of the top 20 diseases related to Hand Skill, Relative:



Diseases related to Hand Skill, Relative

Symptoms & Phenotypes for Hand Skill, Relative

Symptoms via clinical synopsis from OMIM:

56
Misc:
handedness

Clinical features from OMIM:

139900

Drugs & Therapeutics for Hand Skill, Relative

Drugs for Hand Skill, Relative (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 157)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved Phase 4 58-08-2 2519
2
Sertraline Approved Phase 4 79617-96-2 68617
3
Topiramate Approved Phase 4 97240-79-4 5284627
4
Citalopram Approved Phase 4 59729-33-8 2771
5
Pramipexole Approved, Investigational Phase 4 104632-26-0 59868 119570
6
Ziprasidone Approved Phase 4 146939-27-7 60854
7
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
8
Maprotiline Approved, Investigational Phase 4 10262-69-8 4011
9
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
10
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
11
Imipramine Approved Phase 4 50-49-7 3696
12
Moclobemide Approved, Investigational Phase 4 71320-77-9 4235
13
Clozapine Approved Phase 4 5786-21-0 2818
14
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
15
Nortriptyline Approved Phase 4 72-69-5 4543
16
Phenelzine Approved Phase 4 51-71-8 3675
17
Fluvoxamine Approved, Investigational Phase 4 54739-18-3 3404 5324346
18
Desipramine Approved, Investigational Phase 4 50-47-5 2995
19
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
20
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
21
Pindolol Approved, Investigational Phase 4 13523-86-9 4828
22
Amitriptyline Approved Phase 4 50-48-6 2160
23
Doxepin Approved, Investigational Phase 4 1668-19-5 667477 667468
24
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
25
Protriptyline Approved Phase 4 438-60-8 4976
26
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
27
Isocarboxazid Approved Phase 4 59-63-2 3759
28
Clomipramine Approved, Investigational, Vet_approved Phase 4 303-49-1 2801
29
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
30
Lithium carbonate Approved Phase 4 554-13-2
31
Trimipramine Approved Phase 4 739-71-9 5584 4055
32
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
33
Budesonide Approved Phase 4 51333-22-3 63006 5281004
34
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
35
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
36
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
37
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
38 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
39
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
40
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
41
Taurine Approved, Nutraceutical Phase 4 107-35-7 1123
42
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
43 Sodium Channel Blockers Phase 4
44 Diuretics, Potassium Sparing Phase 4
45 Amitriptyline, perphenazine drug combination Phase 4
46 Atomoxetine Hydrochloride Phase 4
47 Venlafaxine Hydrochloride Phase 4
48 Quetiapine Fumarate Phase 4 111974-72-2
49 Respiratory System Agents Phase 4
50 Anti-Asthmatic Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 110)
# Name Status NCT ID Phase Drugs
1 Transcranial Direct Current Stimulation (TDCS) as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy - Active and Placebo Controlled Double Blind Study Unknown status NCT01729507 Phase 4
2 The Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students Completed NCT02535143 Phase 4 Taurine
3 A Randomized Clinical Trial of Cutaneous Xylocaine Spray to Reduce Intravenous Cannulation Pain in Adults Completed NCT02562144 Phase 4 Xylocaine spray;Placebo
4 Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism Completed NCT00704860 Phase 4
5 Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses Completed NCT02219438 Phase 4 ropivacaine
6 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device: A Randomized, Single-blind, Parallel Trial Comparing the Lying-Head-Back Versus the Head-Down-to-Floor Positions Completed NCT02079792 Phase 4
7 The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint: A Randomized Control Trial Not yet recruiting NCT04177433 Phase 4 Depo-Medrol Injectable Product;Saline
8 A Randomized, Double-blind Controlled Trial of Bupivacaine Extended-release Liposome Injection for Postsurgical Analgesia in Patients Undergoing Open-reduction Internal Fixation of the Distal Radius Terminated NCT02515851 Phase 4 Exparel;Placebo
9 The Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy Withdrawn NCT03711097 Phase 4 Vanish XT Dental Varnish
10 A Prospective, Randomized, Open-label, Multicenter Study Evaluating the Effects on Cognitive Functions of Adjuvant Endocrine Therapy in Postmenopausal Women With Breast Cancer. Unknown status NCT00893061 Phase 3 anastrozole;exemestane;letrozole;tamoxifen citrate
11 Metformin in Alzheimer's Dementia Prevention Not yet recruiting NCT04098666 Phase 2, Phase 3 Placebo oral tablet;extended release metformin
12 Basis for an Etiological Diagnosis and Treatment of the Chronic TMD-pain: RCT Study Completed NCT00899717 Phase 1, Phase 2
13 Stroke Inpatient Rehabilitation Reinforcement of Walking Speed Completed NCT00428480 Phase 1
14 N-Acetylcysteine in the Treatment of Deliberate Self-Harm in Adolescents: An Open Label Pilot Study Completed NCT01111734 Phase 1 fMRI
15 OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DELAY AND DEAFNESS: A PROSPECTIVE, RANDOMIZED TRIAL Completed NCT01256229 Phase 1
16 Changes in Brain Synchronization During Perceptual and Linguistic Tasks in Schizophrenic Patients Unknown status NCT01550211
17 Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder: a Follow-up Study Unknown status NCT02233348
18 Gestural Short Term and Working Memory Task Unknown status NCT02859649
19 Does Standardizing Language in Laparoscopic Surgery Improve Efficiency? A Randomized Controlled Trial Unknown status NCT02565875
20 Structural and Functional Connectivity in Autism Spectrum Disorders by Using Diffusion Spectrum Imaging and Functional Magnetic Resonance Imaging Studies Unknown status NCT00755430
21 Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders Unknown status NCT01513629
22 Neuropsychology, Neuroimage and Neurophysiology in Adults With Attention-Deficit Hyperactivity Disorder: An Endophenotype and Follow-up Study Unknown status NCT02642068
23 Neuropsychopathological Study of Autism: From Clinical, Neurocognitive, to Genetic Studies and Animal Models Unknown status NCT01677663
24 Examining the Neural Bases of Early Visual and Auditory Processing and Emotion Recognition Deficits in Schizophrenia Using Magnetoencephalography Unknown status NCT02588014
25 Adult Outcome of Children With Attention-deficit/Hyperactivity Disorder Unknown status NCT01247610
26 A Randomized Study of Non-Operative Management Versus Expedited Surgery Among WCB Patients With Small Rotator Cuff Tears: Affect Upon Time to Claim Closure in 2 Prairie Provinces Unknown status NCT01498198
27 Type II Pediatric Supracondylar Humerus Fracture Management and Outcomes: A Prospective Multi-centre Cohort Study Unknown status NCT02963233
28 The Use of Transcranial Electrical Stimulation for Hallucinations Unknown status NCT02715765
29 Mapping the Genetic Component of Hand-Use Preference Completed NCT00005003
30 Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects Completed NCT02523742
31 Asymmetry, Auditory Processing and Reading Skills in Phonological Dyslexic Children Compared to Average-reading Children Completed NCT02345876
32 Validity and Reliability of an Activity Monitor in Persons With a Cerebrovascular Accident Completed NCT00849446
33 Knowing and Remembering: Cognitive and Neural Influences of Familiarity on Recognition Memory in Early Alzheimer's Disease Completed NCT02492529
34 Volumetric Brain MRI (Magnetic Resonance Imaging) Comparison of Patients With Treatment Resistant Depression (TRD) Undergoing Deep Brain Stimulation (DBS) With Age, Sex and Education Matched Healthy Controls Completed NCT01162434
35 Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease Completed NCT03580486
36 Neuromodulation With rTMS in Dysphagic Patients With Stroke Completed NCT02893033
37 Validating a New Writer's Cramp Scale Completed NCT01579266
38 Anatomical and Functional MRI Study of Episodic Memory in Epileptic Compared to Normal Children Completed NCT00242905
39 Measurement of Induced Strains in the Human Tibia During Vibration Therapy and Habitual Activities Completed NCT01430858
40 Investigation of the Effects of Independent Transfer Training Completed NCT03160612
41 Motor Memory: Study of the Role of Dopamine in Healthy Subjects and Patients With Parkinson's Disease Using PET and EEG Completed NCT00032812 Raclopride
42 Test-retest Reliability of Measuring the Area and Intensity of Secondary Hyperalgesia Induced by High Frequency Stimulation of Skin Nociceptors Completed NCT03966508
43 The Role of the Prefrontal Cortex in Economic Decision-Making in Reciprocal Trust Games Using Functional Hyperscanning Neuroimaging Completed NCT00083317
44 Comparison of Anti-craving Efficacy of Right and Left Prefrontal High Frequency rTMS in Alcohol Dependence: a Randomized Double-blind Study Completed NCT01093716
45 Functional Connectivity of the Basal Ganglia in Primary Focal Dystonia Completed NCT01761903
46 FEATHERS 2.0: Functional Engagement in Assistive Therapy Through Exercise Robotics v2.0 Completed NCT03766711
47 MEG Study of Altered Sensory Processing in Tourette Syndrome: An Exploration of Sensory Tics Completed NCT00141869
48 Improvement of Motor Performance in Chronic Stroke Patients by Combined Transcranial DC Stimulation and Somatosensory Stimulation Completed NCT00110175
49 Modulation of the Visual Information Processing in the Human Parieto-Frontal Network as Studied by a Frequency Tagging Technique During Visuomotor Tracking Completed NCT00077038
50 Role of the Right Brain in Recovery of Language Function in Chronic Stroke Completed NCT00076479

Search NIH Clinical Center for Hand Skill, Relative

Genetic Tests for Hand Skill, Relative

Anatomical Context for Hand Skill, Relative

MalaCards organs/tissues related to Hand Skill, Relative:

40
Brain, Testes, Cortex, Eye, Temporal Lobe, Breast, Bone

Publications for Hand Skill, Relative

Articles related to Hand Skill, Relative:

(show top 50) (show all 6824)
# Title Authors PMID Year
1
Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11. 61 56
14583442 2003
2
Human handedness and scalp hair-whorl direction develop from a common genetic mechanism. 61 56
14504234 2003
3
Parametric and non-parametric linkage analysis of several candidate regions for genes for human handedness. 56 61
12357333 2002
4
Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. 61 56
11867730 2002
5
A genomewide linkage screen for relative hand skill in sibling pairs. 61 56
11774074 2002
6
Individual differences in handedness and specific speech and language impairment: evidence against a genetic link. 61 56
11720120 2001
7
A gene-culture model of human handedness. 56 61
7487840 1995
8
Handedness and life span. 56 61
2002827 1991
9
Left handedness is uncommon in breast cancer patients. 56 61
1782085 1991
10
Handedness in systemic lupus erythematosus. 61 56
3964317 1986
11
Left-handedness: association with immune disease, migraine, and developmental learning disorder. 61 56
6956919 1982
12
Family handedness in three generations predicted by the right shift theory. 56 61
475335 1979
13
Laterality in twins: the relationship between handedness and hemispheric asymmetry for speech. 61 56
567977 1978
14
Genetic and nongenetic influences on handedness. 61 56
687316 1978
15
Fifty centuries of right-handedness: the historical record. 56 61
335510 1977
16
Concerning the origin of handedness in humans. 56 61
843315 1977
17
A review of evidence for a genetic component in the determination of handedness. 61 56
791243 1976
18
Human handedness: a partial cross-fostering study. 56 61
1273577 1976
19
Preferences for handedness, arm folding, and hand clasping in families. 61 56
4461659 1974
20
Handedness in families. 61 56
4759906 1973
21
A model for the genetics of handedness. 61 56
5073852 1972
22
A MODEL OF THE INHERITANCE OF HANDEDNESS AND CEREBRAL DOMINANCE. 56 61
14240116 1964
23
Handedness, with Special Reference to Twins. 61 56
17246963 1940
24
Confirmatory evidence for linkage of relative hand skill to 2p12-q11. 56
12596796 2003
25
A single locus, RGHT, specifies preference for hand utilization in humans. 56
9246435 1996
26
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. 56
7581446 1995
27
Do right-handers live longer? 56
3367996 1988
28
A longitudinal birth cohort study of early life conditions, psychosocial factors, and emerging adolescent sexual orientation. 61
31378935 2020
29
Common and distinct neural activities in frontoparietal network in first-episode bipolar disorder and major depressive disorder: Preliminary findings from a follow-up resting state fMRI study. 61
31542559 2020
30
Laterality and risk factors for ulnar neuropathy at the elbow. 61
31599458 2020
31
Handedness in plant cell expansion: a mutant perspective on helical growth. 61
31254400 2020
32
Effects of Fencing Training on Motor Performance and Asymmetry Vary With Handedness. 61
30849297 2020
33
Right-hemispheric Dominance in Self-body Recognition is Altered in Left-handed Individuals. 61
31809726 2019
34
Local Optical Chirality Induced by Near-Field Mode Interference in Achiral Plasmonic Metamolecules. 61
31816242 2019
35
Activity in the prefrontal cortex during motor imagery of precision gait: an fNIRS study. 61
31834451 2019
36
Chiral fermion reversal in chiral crystals. 61
31796737 2019
37
Room-Temperature Active Modulation of Valley Dynamics in a Monolayer Semiconductor through Chiral Purcell Effects. 61
31621963 2019
38
Controlling the spin-selective absorption with two-dimensional chiral plasmonic gratings. 61
31774800 2019
39
Spin-dependent charge transport through 2D chiral hybrid lead-iodide perovskites. 61
31840072 2019
40
Interhemispheric Activation and Memory Function: Considerations and Recommendations in the Context of Cardiovascular Exercise Research. 61
30060715 2019
41
Schizotypy and altered hemispheric asymmetries: The role of cilia genes. 61
31683112 2019
42
Hyper-Rayleigh Scattering as a New Chiroptical Method: Uncovering the Nonlinear Optical Activity of Aromatic Oligoamide Foldamers. 61
31825211 2019
43
Abnormal Frequency Mismatch Negativity in Early Psychosis Outpatient Subjects. 61
31826666 2019
44
Hemispheric lateralization does not affect the cognitive and mechanical cost of a sequential motor task. 61
31559448 2019
45
Valley controlled Andreev reflection and valley-switch effect in graphene-based superconducting hybrid structures. 61
31342937 2019
46
Psychometric properties of the Spanish version of the Edinburgh Handedness Inventory in a sample of Chilean undergraduates. 61
31629000 2019
47
Visible Light-Driven Halogen Bond Donor Based Molecular Switches: From Reversible Unwinding to Handedness Inversion in Self-Organized Soft Helical Superstructures. 61
31802595 2019
48
Reversible chirality inversion of circularly polarized luminescence in a photo-invertible helical cholesteric superstructure. 61
31742268 2019
49
Frustration and Emotional Regulation in Nonsyndromic Craniosynostosis: A Functional Magnetic Resonance Imaging Study. 61
31764655 2019
50
Arthroscopic debridement for osteoarthritis of the elbow: Results and analysis of predictive factors. 61
31540887 2019

Variations for Hand Skill, Relative

Expression for Hand Skill, Relative

Search GEO for disease gene expression data for Hand Skill, Relative.

Pathways for Hand Skill, Relative

GO Terms for Hand Skill, Relative

Sources for Hand Skill, Relative

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....