Aliases & Classifications for Hand Skill, Relative

MalaCards integrated aliases for Hand Skill, Relative:

Name: Hand Skill, Relative 56 13
Handedness 17
Hsr 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant vs. multifactorial


HPO:

31
hand skill, relative:
Inheritance autosomal dominant inheritance


External Ids:

OMIM 56 139900
MedGen 41 C0023114
SNOMED-CT via HPO 68 263681008

Summaries for Hand Skill, Relative

MalaCards based summary : Hand Skill, Relative, also known as handedness, is related to ocular dominance and helix syndrome. An important gene associated with Hand Skill, Relative is HSR (Hand Skill, Relative). The drugs Caffeine and Pindolol have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and cortex.

More information from OMIM: 139900

Related Diseases for Hand Skill, Relative

Diseases related to Hand Skill, Relative via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 249)
# Related Disease Score Top Affiliating Genes
1 ocular dominance 11.8
2 helix syndrome 10.5
3 dyslexia 10.5
4 schizophrenia 10.5
5 neuroblastoma 10.4
6 autism 10.4
7 stuttering 10.4
8 leukemia, acute myeloid 10.3
9 migraine with or without aura 1 10.3
10 autoimmune disease 10.3
11 hair whorl 10.3
12 schizotypal personality disorder 10.3
13 aphasia 10.3
14 myelodysplastic syndrome 10.3
15 allergic hypersensitivity disease 10.3
16 myeloid leukemia 10.3
17 learning disability 10.2
18 alcohol dependence 10.2
19 anxiety 10.2
20 autism spectrum disorder 10.2
21 chromosomal triplication 10.2
22 ring chromosome 10.2
23 refractory anemia 10.2
24 breast cancer 10.2
25 strabismus 10.2
26 scoliosis 10.2
27 epilepsy 10.2
28 mechanical strabismus 10.2
29 dermatitis 10.1
30 situs inversus 10.1
31 osteoarthritis 10.1
32 cleft lip 10.1
33 tremor 10.1
34 attention deficit-hyperactivity disorder 10.1
35 major affective disorder 8 10.1
36 major affective disorder 9 10.1
37 speech and communication disorders 10.1
38 pedophilia 10.1
39 bipolar disorder 10.1
40 temporal lobe epilepsy 10.1
41 headache 10.1
42 cleft palate, isolated 10.1
43 apraxia 10.1
44 idiopathic scoliosis 10.1
45 personality disorder 10.1
46 cerebral palsy 10.1
47 developmental coordination disorder 10.1
48 developmental dyspraxia 10.1
49 cleft lip with or without cleft palate 10.1
50 colorectal cancer 10.0

Graphical network of the top 20 diseases related to Hand Skill, Relative:



Diseases related to Hand Skill, Relative

Symptoms & Phenotypes for Hand Skill, Relative

Symptoms via clinical synopsis from OMIM:

56
Misc:
handedness

Clinical features from OMIM:

139900

Drugs & Therapeutics for Hand Skill, Relative

Drugs for Hand Skill, Relative (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 157)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved Phase 4 58-08-2 2519
2
Pindolol Approved, Investigational Phase 4 13523-86-9 4828
3
Maprotiline Approved, Investigational Phase 4 10262-69-8 4011
4
Topiramate Approved Phase 4 97240-79-4 5284627
5
Sertraline Approved Phase 4 79617-96-2 68617
6
Isocarboxazid Approved Phase 4 59-63-2 3759
7
Pramipexole Approved, Investigational Phase 4 104632-26-0 59868 119570
8
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
9
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
10
Nortriptyline Approved Phase 4 72-69-5 4543
11
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
12
Lithium carbonate Approved Phase 4 554-13-2
13
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
14
Clomipramine Approved, Investigational, Vet_approved Phase 4 303-49-1 2801
15
Desipramine Approved, Investigational Phase 4 50-47-5 2995
16
Phenelzine Approved Phase 4 51-71-8 3675
17
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
18
Citalopram Approved Phase 4 59729-33-8 2771
19
Moclobemide Approved, Investigational Phase 4 71320-77-9 4235
20
Fluvoxamine Approved, Investigational Phase 4 54739-18-3 3404 5324346
21
Imipramine Approved Phase 4 50-49-7 3696
22
Doxepin Approved, Investigational Phase 4 1668-19-5 667477 667468
23
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
24
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
25
Amitriptyline Approved Phase 4 50-48-6 2160
26
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
27
Protriptyline Approved Phase 4 438-60-8 4976
28
Clozapine Approved Phase 4 5786-21-0 2818
29
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
30
Trimipramine Approved Phase 4 739-71-9 5584 4055
31
Ziprasidone Approved Phase 4 146939-27-7 60854
32
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
33
Budesonide Approved Phase 4 51333-22-3 63006 5281004
34
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
35
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
36
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
37 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
38
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
39
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
40
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
41
Taurine Approved, Nutraceutical Phase 4 107-35-7 1123
42
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
43 Sodium Channel Blockers Phase 4
44 Diuretics, Potassium Sparing Phase 4
45 Atomoxetine Hydrochloride Phase 4
46 Venlafaxine Hydrochloride Phase 4
47 Amitriptyline, perphenazine drug combination Phase 4
48 Quetiapine Fumarate Phase 4 111974-72-2
49 Respiratory System Agents Phase 4
50 Anti-Asthmatic Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 110)
# Name Status NCT ID Phase Drugs
1 Transcranial Direct Current Stimulation (TDCS) as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy - Active and Placebo Controlled Double Blind Study Unknown status NCT01729507 Phase 4
2 The Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students Completed NCT02535143 Phase 4 Taurine
3 A Randomized Clinical Trial of Cutaneous Xylocaine Spray to Reduce Intravenous Cannulation Pain in Adults Completed NCT02562144 Phase 4 Xylocaine spray;Placebo
4 Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism Completed NCT00704860 Phase 4
5 Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses Completed NCT02219438 Phase 4 ropivacaine
6 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device: A Randomized, Single-blind, Parallel Trial Comparing the Lying-Head-Back Versus the Head-Down-to-Floor Positions Completed NCT02079792 Phase 4
7 The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint: A Randomized Control Trial Not yet recruiting NCT04177433 Phase 4 Depo-Medrol Injectable Product;Saline
8 A Randomized, Double-blind Controlled Trial of Bupivacaine Extended-release Liposome Injection for Postsurgical Analgesia in Patients Undergoing Open-reduction Internal Fixation of the Distal Radius Terminated NCT02515851 Phase 4 Exparel;Placebo
9 The Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions During Fixed Appliance Orthodontic Therapy Withdrawn NCT03711097 Phase 4 Vanish XT Dental Varnish
10 A Prospective, Randomized, Open-label, Multicenter Study Evaluating the Effects on Cognitive Functions of Adjuvant Endocrine Therapy in Postmenopausal Women With Breast Cancer. Unknown status NCT00893061 Phase 3 anastrozole;exemestane;letrozole;tamoxifen citrate
11 Metformin in Alzheimer's Dementia Prevention Not yet recruiting NCT04098666 Phase 2, Phase 3 Placebo oral tablet;extended release metformin
12 Basis for an Etiological Diagnosis and Treatment of the Chronic TMD-pain: RCT Study Completed NCT00899717 Phase 1, Phase 2
13 Stroke Inpatient Rehabilitation Reinforcement of Walking Speed Completed NCT00428480 Phase 1
14 N-Acetylcysteine in the Treatment of Deliberate Self-Harm in Adolescents: An Open Label Pilot Study Completed NCT01111734 Phase 1 fMRI
15 OUTCOMES IN CHILDREN WITH DEVELOPMENTAL DELAY AND DEAFNESS: A PROSPECTIVE, RANDOMIZED TRIAL Completed NCT01256229 Phase 1
16 Changes in Brain Synchronization During Perceptual and Linguistic Tasks in Schizophrenic Patients Unknown status NCT01550211
17 Gestural Short Term and Working Memory Task Unknown status NCT02859649
18 Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder: a Follow-up Study Unknown status NCT02233348
19 Does Standardizing Language in Laparoscopic Surgery Improve Efficiency? A Randomized Controlled Trial Unknown status NCT02565875
20 Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders Unknown status NCT01513629
21 Structural and Functional Connectivity in Autism Spectrum Disorders by Using Diffusion Spectrum Imaging and Functional Magnetic Resonance Imaging Studies Unknown status NCT00755430
22 Neuropsychology, Neuroimage and Neurophysiology in Adults With Attention-Deficit Hyperactivity Disorder: An Endophenotype and Follow-up Study Unknown status NCT02642068
23 Examining the Neural Bases of Early Visual and Auditory Processing and Emotion Recognition Deficits in Schizophrenia Using Magnetoencephalography Unknown status NCT02588014
24 Neuropsychopathological Study of Autism: From Clinical, Neurocognitive, to Genetic Studies and Animal Models Unknown status NCT01677663
25 Adult Outcome of Children With Attention-deficit/Hyperactivity Disorder Unknown status NCT01247610
26 A Randomized Study of Non-Operative Management Versus Expedited Surgery Among WCB Patients With Small Rotator Cuff Tears: Affect Upon Time to Claim Closure in 2 Prairie Provinces Unknown status NCT01498198
27 Type II Pediatric Supracondylar Humerus Fracture Management and Outcomes: A Prospective Multi-centre Cohort Study Unknown status NCT02963233
28 The Use of Transcranial Electrical Stimulation for Hallucinations Unknown status NCT02715765
29 Mapping the Genetic Component of Hand-Use Preference Completed NCT00005003
30 Study of the Hemispheric Specialization for Language in Subjects With Neuropsychiatric Disorders Compared to Control Subjects Completed NCT02523742
31 Asymmetry, Auditory Processing and Reading Skills in Phonological Dyslexic Children Compared to Average-reading Children Completed NCT02345876
32 Knowing and Remembering: Cognitive and Neural Influences of Familiarity on Recognition Memory in Early Alzheimer's Disease Completed NCT02492529
33 Validity and Reliability of an Activity Monitor in Persons With a Cerebrovascular Accident Completed NCT00849446
34 Volumetric Brain MRI (Magnetic Resonance Imaging) Comparison of Patients With Treatment Resistant Depression (TRD) Undergoing Deep Brain Stimulation (DBS) With Age, Sex and Education Matched Healthy Controls Completed NCT01162434
35 Neuromodulation With rTMS in Dysphagic Patients With Stroke Completed NCT02893033
36 Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease Completed NCT03580486
37 Validating a New Writer's Cramp Scale Completed NCT01579266
38 Anatomical and Functional MRI Study of Episodic Memory in Epileptic Compared to Normal Children Completed NCT00242905
39 Investigation of the Effects of Independent Transfer Training Completed NCT03160612
40 Measurement of Induced Strains in the Human Tibia During Vibration Therapy and Habitual Activities Completed NCT01430858
41 Motor Memory: Study of the Role of Dopamine in Healthy Subjects and Patients With Parkinson's Disease Using PET and EEG Completed NCT00032812 Raclopride
42 Test-retest Reliability of Measuring the Area and Intensity of Secondary Hyperalgesia Induced by High Frequency Stimulation of Skin Nociceptors Completed NCT03966508
43 FEATHERS 2.0: Functional Engagement in Assistive Therapy Through Exercise Robotics v2.0 Completed NCT03766711
44 The Role of the Prefrontal Cortex in Economic Decision-Making in Reciprocal Trust Games Using Functional Hyperscanning Neuroimaging Completed NCT00083317
45 Comparison of Anti-craving Efficacy of Right and Left Prefrontal High Frequency rTMS in Alcohol Dependence: a Randomized Double-blind Study Completed NCT01093716
46 Functional Connectivity of the Basal Ganglia in Primary Focal Dystonia Completed NCT01761903
47 Deliberate Practice With Validated Metrics Improves Skill Acquisition in Performance of Ultrasound Guided Peripheral Nerve Block in a Simulated Setting Completed NCT03154372
48 MEG Study of Altered Sensory Processing in Tourette Syndrome: An Exploration of Sensory Tics Completed NCT00141869
49 FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression Completed NCT00075296
50 Cross-Modal Plasticity of Verbal Memory in the Blind Completed NCT00059189

Search NIH Clinical Center for Hand Skill, Relative

Genetic Tests for Hand Skill, Relative

Anatomical Context for Hand Skill, Relative

MalaCards organs/tissues related to Hand Skill, Relative:

40
Brain, Testes, Cortex, Eye, Temporal Lobe, Breast, Bone

Publications for Hand Skill, Relative

Articles related to Hand Skill, Relative:

(show top 50) (show all 6870)
# Title Authors PMID Year
1
Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11. 61 56
14583442 2003
2
Human handedness and scalp hair-whorl direction develop from a common genetic mechanism. 61 56
14504234 2003
3
Parametric and non-parametric linkage analysis of several candidate regions for genes for human handedness. 61 56
12357333 2002
4
A genomewide linkage screen for relative hand skill in sibling pairs. 61 56
11774074 2002
5
Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. 61 56
11867730 2002
6
Individual differences in handedness and specific speech and language impairment: evidence against a genetic link. 61 56
11720120 2001
7
A gene-culture model of human handedness. 61 56
7487840 1995
8
Handedness and life span. 61 56
2002827 1991
9
Left handedness is uncommon in breast cancer patients. 61 56
1782085 1991
10
Left-handedness: association with immune disease, migraine, and developmental learning disorder. 61 56
6956919 1982
11
Family handedness in three generations predicted by the right shift theory. 61 56
475335 1979
12
Laterality in twins: the relationship between handedness and hemispheric asymmetry for speech. 61 56
567977 1978
13
Genetic and nongenetic influences on handedness. 61 56
687316 1978
14
Fifty centuries of right-handedness: the historical record. 61 56
335510 1977
15
Concerning the origin of handedness in humans. 61 56
843315 1977
16
A review of evidence for a genetic component in the determination of handedness. 61 56
791243 1976
17
Human handedness: a partial cross-fostering study. 61 56
1273577 1976
18
Preferences for handedness, arm folding, and hand clasping in families. 61 56
4461659 1974
19
Handedness in families. 61 56
4759906 1973
20
A model for the genetics of handedness. 61 56
5073852 1972
21
A MODEL OF THE INHERITANCE OF HANDEDNESS AND CEREBRAL DOMINANCE. 61 56
14240116 1964
22
Handedness, with Special Reference to Twins. 61 56
17246963 1940
23
Confirmatory evidence for linkage of relative hand skill to 2p12-q11. 56
12596796 2003
24
A single locus, RGHT, specifies preference for hand utilization in humans. 56
9246435 1996
25
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. 56
7581446 1995
26
Do right-handers live longer? 56
3367996 1988
27
Cerebral laterality as assessed by hand preference measures and developmental stuttering. 61
31144576 2020
28
Rightward directional bias in art produced by cultures without a written language. 61
31242803 2020
29
Visible-Light-Driven Halogen Bond Donor Based Molecular Switches: From Reversible Unwinding to Handedness Inversion in Self-Organized Soft Helical Superstructures. 61
31802595 2020
30
Correlation of lateral ventricular size and deep gray matter volume in MRI at term equivalent age with neurodevelopmental outcome at a corrected age of 24 months and with handedness in preterm infants. 61
31724086 2020
31
High-energy 2  µm pulsed vortex beam excitation from a Q-switched Tm:LuYAG laser. 61
32004294 2020
32
Effect of Chiral Molecules on the Electron's Spin Wavefunction at Interfaces. 61
32013436 2020
33
Chiral Reaction Field with Thermally Invertible Helical Sense that Controls the Helicities of Conjugated Polymers. 61
32027067 2020
34
Saccade accuracy as an indicator of the competition between functional asymmetries in vision. 61
31932866 2020
35
Alterations in brain white matter microstructural properties in patients with Crohn's disease in remission. 61
32034257 2020
36
Handedness heritability in industrialized and nonindustrialized societies. 61
31602008 2020
37
The effects of handedness on sensorimotor rhythm desynchronization and motor-imagery BCI control. 61
32034277 2020
38
Functional lateralization of arithmetic processing in the intraparietal sulcus is associated with handedness. 61
32020021 2020
39
Handedness of structural units depends on their mutual arrangement in protein structure. 61
30776980 2020
40
Optical field tuning of localized plasmon modes in Ag microcrystals at the nanofemto scale. 61
32035439 2020
41
Assessing various sensorimotor and cognitive functions in people with epilepsy is feasible with robotics. 61
31918991 2020
42
Clinical characteristics of video-EEG patients: Limited utility of prolonging VEEG study duration beyond 5 days for spell classification. 61
31882323 2020
43
The Chiral Looping of the Embryonic Heart Is Formed by the Combination of Three Axial Asymmetries. 61
31952803 2020
44
A comparison study assessing neuropsychological outcome of patients with post-operative pediatric cerebellar mutism syndrome and matched controls after proton radiation therapy. 61
31325031 2020
45
Impaired coherence for semantic but not episodic autobiographical memory in semantic variant primary progressive aphasia. 61
31760339 2020
46
Missing Link between Helical Nano- and Microfilaments in B4 Phase Bent-Core Liquid Crystals, and Deciphering which Chiral Center Controls the Filament Handedness. 61
31885139 2020
47
Parallel Homochiral and Anti-Parallel Heterochiral Hydrogen-Bonding Interfaces in Multi-Helical Abiotic Foldamers. 61
31671236 2020
48
Single-walled carbon nanotube absolute-handedness chirality assignment confirmation using metalized porphyrin's supramolecular structures via STM imaging technique. 61
31909860 2020
49
Right-hemispheric Dominance in Self-body Recognition is Altered in Left-handed Individuals. 61
31809726 2020
50
Preschool language ability is predicted by toddler hand preference trajectories. 61
31999182 2020

Variations for Hand Skill, Relative

Expression for Hand Skill, Relative

Search GEO for disease gene expression data for Hand Skill, Relative.

Pathways for Hand Skill, Relative

GO Terms for Hand Skill, Relative

Sources for Hand Skill, Relative

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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