MCID: HRD005
MIFTS: 47

Hard Palate Cancer

Categories: Cancer diseases, Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Hard Palate Cancer

MalaCards integrated aliases for Hard Palate Cancer:

Name: Hard Palate Cancer 12 15
Hard Palate 12 15
Malignant Tumor of the Hard Palate 12
Malignant Neoplasm of Hard Palate 12
Malignant Tumour of Hard Palate 12
Malignant Tumor of Hard Palate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9149
ICD10 33 C05.0
ICD9CM 35 145.2
NCIt 50 C3528
SNOMED-CT 68 93822006
UMLS 73 C0153375

Summaries for Hard Palate Cancer

MalaCards based summary : Hard Palate Cancer, also known as hard palate, is related to cleft palate, isolated and cleft palate with or without ankyloglossia, x-linked. An important gene associated with Hard Palate Cancer is SHOX2 (Short Stature Homeobox 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Differentiation Pathway. Affiliated tissues include tongue, bone and salivary gland, and related phenotypes are craniofacial and digestive/alimentary

Related Diseases for Hard Palate Cancer

Diseases related to Hard Palate Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)
# Related Disease Score Top Affiliating Genes
1 cleft palate, isolated 31.7 MSX1 NANS SHOX2 SMCP TBX22 TMEM54
2 cleft palate with or without ankyloglossia, x-linked 30.9 MSX1 NOTCH1 SMCP TBX22
3 cleft hard palate 12.5
4 necrotizing sialometaplasia 11.3
5 cleft lip/palate 11.1
6 endosteal hyperostosis, autosomal dominant 11.0
7 torus palatinus and torus mandibularis 11.0
8 microtia, hearing impairment, and cleft palate 11.0
9 cleft palate, psychomotor retardation, and distinctive facial features 11.0
10 warty dyskeratoma 11.0
11 cleft lip 10.6
12 squamous cell carcinoma 10.5
13 adenoma 10.4
14 lymphoma 10.4
15 pleomorphic adenoma 10.4
16 sarcoma 10.4
17 melanoma 10.4
18 myoepithelioma 10.3
19 papilloma 10.2
20 leukemia 10.2
21 teratoma 10.2
22 mucoepidermoid carcinoma 10.2
23 down syndrome 10.1
24 leukemia, acute lymphoblastic 10.1
25 b-cell lymphomas 10.1
26 adenoid cystic carcinoma 10.1
27 lymphocytic leukemia 10.1
28 adenocarcinoma 10.1
29 diffuse large b-cell lymphoma 10.1
30 mantle cell lymphoma 10.1
31 epithelial-myoepithelial carcinoma 10.1
32 mucormycosis 10.1
33 psoriasis 10.1
34 polymorphous low-grade adenocarcinoma 10.1
35 frontal sinusitis 10.1 NOTCH1 RHNO1
36 kaposi sarcoma 10.0
37 chondrosarcoma 10.0
38 lymphoma, hodgkin, classic 10.0
39 sarcoma, synovial 10.0
40 langerhans cell histiocytosis 10.0
41 lymphoma, non-hodgkin, familial 10.0
42 severe cutaneous adverse reaction 10.0
43 hemangioma 10.0
44 salivary gland carcinoma 10.0
45 osteomyelitis 10.0
46 melanoacanthoma 10.0
47 entropion 10.0
48 cicatricial entropion 10.0
49 hyperparathyroidism 10.0
50 squamous cell papilloma 10.0

Graphical network of the top 20 diseases related to Hard Palate Cancer:



Diseases related to Hard Palate Cancer

Symptoms & Phenotypes for Hard Palate Cancer

MGI Mouse Phenotypes related to Hard Palate Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.86 BARX1 FGF10 KRT14 KRT4 MSX1 NOTCH1
2 digestive/alimentary MP:0005381 9.76 BARX1 FGF10 KRT14 KRT4 MSX1 NOTCH1
3 integument MP:0010771 9.43 FGF10 KRT14 KRT4 MSX1 NOTCH1 PCCA
4 mortality/aging MP:0010768 9.28 BARX1 FGF10 KRT14 KRT4 MSX1 NOTCH1

Drugs & Therapeutics for Hard Palate Cancer

Search Clinical Trials , NIH Clinical Center for Hard Palate Cancer

Genetic Tests for Hard Palate Cancer

Anatomical Context for Hard Palate Cancer

MalaCards organs/tissues related to Hard Palate Cancer:

41
Tongue, Bone, Salivary Gland, B Cells, Myeloid, Testes, Tonsil

Publications for Hard Palate Cancer

Articles related to Hard Palate Cancer:

(show top 50) (show all 608)
# Title Authors Year
1
Adenoid cystic carcinoma of the hard palate presenting as ipsilateral sixth nerve palsy. ( 30038189 )
2018
2
Maxillary Growth in Cleft Lip and Palate Patients, With and Without Vomerine Flap Closure of the Hard Palate at the Time of Lip Repair: A Retrospective Analysis of Prospectively Collected Nonrandomized Data, With 10-Year Cephalometric Outcomes. ( 29652539 )
2018
3
Influence of timing of delayed hard palate closure on articulation skills in 3-year-old Danish children with unilateral cleft lip and palate. ( 28741729 )
2018
4
Correction: Growth of the hard palate in infants with Down syndrome compared with healthy infants-A retrospective case control study. ( 30192886 )
2018
5
Hard Palate Melanoma: A Population-based Analysis of Epidemiology and Survival Outcomes. ( 30275204 )
2018
6
Mucoepidermoid carcinoma of hard palate. ( 30004063 )
2018
7
Squamous Papilloma on Hard Palate: Case Report and Literature Review. ( 30131649 )
2018
8
Three-dimensional morphological evaluation of the hard palate in Korean adults with mild-to-moderate obstructive sleep apnea. ( 29732299 )
2018
9
Leprosy of the hard palate: A rare case report. ( 29491621 )
2018
10
Giant schwannoma of the hard palate: a literature review and report of an uncommon case. ( 29303762 )
2018
11
Hard palate hyperpigmentation-a rare side effect of antimalarials. ( 28941224 )
2018
12
Placement of an antibiotic oral pack on the hard palate after primary cleft palatoplasty: a randomized controlled trial into the effect on fistula rates. ( 29192349 )
2018
13
Closure of fistula of the hard palate with two layers of mucoperiosteum. ( 29287878 )
2018
14
FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. ( 29342370 )
2018
15
The survival impact of surgical therapy in squamous cell carcinoma of the hard palate. ( 29399797 )
2018
16
Modelling human hard palate shape with Bézier curves. ( 29447175 )
2018
17
Unilateral Hard Palate Necrosis After Ascending Palatine Artery Embolization. ( 29521756 )
2018
18
Upper lip tie wrapping into the hard palate and anterior premaxilla causing alveolar hypoplasia. ( 29609432 )
2018
19
Fascia Lata Free Flap Reconstruction of Limited Hard Palate Defects. ( 29805925 )
2018
20
Morphological study of the hard palate in the Egyptian goats (Capra hircus): A scanning electron microscopic study. ( 29877576 )
2018
21
Analysis of blood supply in the hard palate and maxillary tuberosity-clinical implications for flap design and soft tissue graft harvesting (a human cadaver study). ( 29961140 )
2018
22
A score-based method for quality control of fetal hard palate assessment during routine second-trimester ultrasound examination. ( 29964326 )
2018
23
Hard palate-dermis fat composite graft for reconstruction of contracted anophthalmic socket. ( 30089435 )
2018
24
Neuromastoma of the hard palate mucosa in an Australian green tree frog (Litoria caerulea). ( 30111671 )
2018
25
Impact of Hard Palate Angulation Caused by Septal Deviation on Maxillary Sinus Volume. ( 30197803 )
2018
26
Development of Hard and Soft Palate During the Fetal Period and Hard Palate Asymmetry. ( 30320695 )
2018
27
Correction of lower eyelid retraction with hard palate graft in the anophthalmic socket. ( 30340710 )
2018
28
Do gender and age influence hard palate dimensions? A systematic review. ( 30379195 )
2018
29
Suturing a Vomer Flap to the Hard Palate Through a Hole When the Nasal Lining is Not Available. ( 30480636 )
2018
30
Sex prediction by metric and non-metric analysis of the hard palate and the pyriform aperture. ( 30484270 )
2018
31
Individual 3-dimensional printed mold for treating hard palate carcinoma with brachytherapy: A clinical report. ( 30503148 )
2018
32
Collagen gel droplet-embedded culture drug sensitivity testing in hard palate cancer-predicted antitumor efficacy of cetuximab: A case report. ( 28855997 )
2017
33
Human Papillomavirus Infection-Associated Adenoid Cystic Carcinoma of the Hard Palate. ( 28535581 )
2017
34
Basal Cell Adenoma of Hard Palate Involving Maxillary Alveolus. ( 28969742 )
2017
35
Diffuse large B cell lymphoma of hard palate: a case report with literature review. ( 28976132 )
2017
36
Growth of the hard palate in infants with Down syndrome compared with healthy infants-A retrospective case control study. ( 28796822 )
2017
37
Congenital lipoma of the hard palate: case report. ( 28372880 )
2017
38
Prosthetic Management of Hard Palate Perforation in a Child with Acute Lymphoblastic Leukemia. ( 28900336 )
2017
39
Synovial sarcoma of the hard palate: The third case in the medical literature. ( 28183682 )
2017
40
Sarcomatoid Carcinoma of the Hard Palate: An Unusual Cause of Palatal Ulcer. ( 28405558 )
2017
41
Coexistence of hard palate carcinoma with tuberculosis: A rarity. ( 28508849 )
2017
42
Radial Forearm Osteocutaneous Free Flap for Reconstruction of Hard Palate With Alveolar Defect. ( 28538066 )
2017
43
Unusual neoplasm on the hard palate of a child: a case report. ( 28577557 )
2017
44
Solitary Peripheral Osteoma of the Hard Palate Case report and literature review. ( 28690900 )
2017
45
The 2D axial transverse views of the fetal face: A new technique to visualize the fetal hard palate; methodology description and feasibility. ( 29171042 )
2017
46
Can Early Dissection of Cervical Lymph Nodes Improve Prognosis in Squamous Cell Carcinomas of the Hard Palate. ( 29183025 )
2017
47
Hyperpigmentation of the hard palate mucosa in a patient with chronic myeloid leukaemia taking imatinib. ( 29230387 )
2017
48
Hyperpigmentation of hard palate induced by chloroquine therapy. ( 29410767 )
2017
49
Individual scoring and mapping of hard and soft tissues of the anterior hard palate for orthodontic miniscrew insertion. ( 26446347 )
2017
50
Monocortical versus bicortical hard palate anchorage with the same total available cortical thickness: a finite element study. ( 27157504 )
2017

Variations for Hard Palate Cancer

Expression for Hard Palate Cancer

Search GEO for disease gene expression data for Hard Palate Cancer.

Pathways for Hard Palate Cancer

Pathways related to Hard Palate Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.92 FGF10 MSX1 NOTCH1
2 10.84 FGF10 NOTCH1
3 10.62 FGF10 NOTCH1

GO Terms for Hard Palate Cancer

Biological processes related to Hard Palate Cancer according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.75 MSX1 NOTCH1 SHOX2
2 epithelial to mesenchymal transition GO:0001837 9.57 MSX1 NOTCH1
3 positive regulation of BMP signaling pathway GO:0030513 9.56 MSX1 NOTCH1
4 spleen development GO:0048536 9.55 BARX1 FGF10
5 embryonic forelimb morphogenesis GO:0035115 9.54 MSX1 SHOX2
6 pituitary gland development GO:0021983 9.52 FGF10 MSX1
7 embryonic hindlimb morphogenesis GO:0035116 9.51 MSX1 NOTCH1
8 epidermis development GO:0008544 9.5 FGF10 KRT14 NOTCH1
9 branching morphogenesis of an epithelial tube GO:0048754 9.49 FGF10 NOTCH1
10 hair follicle morphogenesis GO:0031069 9.48 FGF10 NOTCH1
11 tissue regeneration GO:0042246 9.46 FGF10 NOTCH1
12 positive regulation of Ras protein signal transduction GO:0046579 9.43 FGF10 NOTCH1
13 embryonic digestive tract morphogenesis GO:0048557 9.4 FGF10 SHOX2
14 regulation of epithelial cell proliferation GO:0050678 9.37 FGF10 NOTCH1
15 epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 9.26 MSX1 NOTCH1
16 cardiac atrium morphogenesis GO:0003209 9.16 NOTCH1 SHOX2
17 embryonic limb morphogenesis GO:0030326 9.13 MSX1 NOTCH1 SHOX2
18 epithelial cell differentiation GO:0030855 8.92 BARX1 FGF10 KRT14 KRT4

Molecular functions related to Hard Palate Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 8.8 BARX1 MSX1 NOTCH1

Sources for Hard Palate Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....