MCID: HDN002
MIFTS: 48

Head Injury

Categories: Neuronal diseases

Aliases & Classifications for Head Injury

Summaries for Head Injury

MedlinePlus : 43 Chances are you've bumped your head before. Often, the injury is minor because your skull is hard and it protects your brain. But other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. Head injuries can be open or closed. A closed injury does not break through the skull. With an open, or penetrating, injury, an object pierces the skull and enters the brain. Closed injuries are not always less severe than open injuries. Some common causes of head injuries are falls, motor vehicle accidents, violence, and sports injuries. It is important to know the warning signs of a moderate or severe head injury. Get help immediately if the injured person has A headache that gets worse or does not go away Repeated vomiting or nausea Convulsions or seizures An inability to wake up Dilated (enlarged) pupil in one or both eyes Slurred speech Weakness or numbness in the arms or legs Loss of coordination Increased confusion, restlessness, or agitation Doctors use a neurologic exam and imaging tests to make a diagnosis. Treatment depends on the type of injury and how severe it is. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Head Injury, also known as head injuries, is related to traumatic brain injury and hydrocephalus. An important gene associated with Head Injury is APOE (Apolipoprotein E), and among its related pathways/superpathways are Neuroscience and JAK-STAT signaling pathway (KEGG). The drugs Aspirin and Galantamine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related phenotypes are behavior/neurological and homeostasis/metabolism

NINDS : 54 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Wikipedia : 76 A head injury is any injury that results in trauma to the skull or brain. The terms traumatic brain... more...

Related Diseases for Head Injury

Diseases related to Head Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 259)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.4 APOE ENO2 S100B
2 hydrocephalus 31.6 APOE ENO2 PRL
3 intracranial cysts 31.6 ENO2 S100B
4 brain injury 30.6 APOE ENO2 S100B
5 persistent vegetative state 30.0 APOE ENO2
6 spondylosis 29.6 ENO2 S100B
7 alexia 29.6 APOE LBR
8 stroke, ischemic 29.6 APOE ENO2 THBD
9 arachnoid cysts 11.4
10 seizure disorder 11.3
11 epilepsy 11.2
12 headache 11.2
13 dementia pugilistica 11.2
14 aphasia 11.2
15 hyperacusis 11.2
16 lennox-gastaut syndrome 11.0
17 diabetes insipidus, neurohypophyseal 10.9
18 cerebral palsy 10.9
19 thrombosis 10.3
20 bednar tumor 10.2 ENO2 S100B
21 senile plaque formation 10.2 APOE CHAT
22 epithelioid malignant peripheral nerve sheath tumor 10.2 ENO2 S100B
23 ossifying fibromyxoid tumor 10.2 ENO2 S100B
24 middle cerebral artery infarction 10.2 ENO2 S100B
25 pineocytoma 10.2 ENO2 S100B
26 papillary ependymoma 10.2 ENO2 S100B
27 ependymoma 10.2 ENO2 S100B
28 granular cell tumor 10.2 ENO2 S100B
29 subependymal giant cell astrocytoma 10.2 ENO2 S100B
30 meningeal melanocytoma 10.2 ENO2 S100B
31 cerebral primitive neuroectodermal tumor 10.2 ENO2 S100B
32 olfactory neuroblastoma 10.2 ENO2 S100B
33 malignant teratoma 10.1 BCL2 ENO2
34 acute mountain sickness 10.1 ENO2 S100B
35 bone ewing's sarcoma 10.1 CHAT ENO2
36 extraosseous ewing's sarcoma 10.1 ENO2 S100B
37 optic nerve glioma 10.1 ENO2 S100B
38 hidradenocarcinoma 10.1 BCL2 S100B
39 pilomatrixoma 10.1 ENO2 S100B
40 rete testis adenocarcinoma 10.1 ENO2 THBD
41 ganglioglioma 10.1 ENO2 S100B
42 osteochondroma 10.1 BCL2 S100B
43 rete testis neoplasm 10.1 ENO2 THBD
44 neurilemmoma 10.1 ENO2 S100B
45 congenital disorder of glycosylation, type iic 10.1 APOE THBD
46 carotid stenosis 10.1 APOE S100B
47 clear cell sarcoma 10.1 ENO2 S100B
48 pericardium cancer 10.1 ENO2 THBD
49 secondary progressive multiple sclerosis 10.1 ENO2 S100B
50 pericardial mesothelioma 10.1 ENO2 THBD

Graphical network of the top 20 diseases related to Head Injury:



Diseases related to Head Injury

Symptoms & Phenotypes for Head Injury

MGI Mouse Phenotypes related to Head Injury:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10 APOE BCL2 CHAT ENO2 LBR PRL
2 homeostasis/metabolism MP:0005376 9.97 APOE BCL2 CHAT IL2RA LBR PRL
3 growth/size/body region MP:0005378 9.95 APOE BCL2 CHAT ENO2 IL2RA LBR
4 digestive/alimentary MP:0005381 9.91 APOE BCL2 CHAT IL2RA LBR THBD
5 integument MP:0010771 9.8 APOE BCL2 LBR PRL S100B THBD
6 nervous system MP:0003631 9.8 APOE BCL2 CHAT ENO2 LBR PRL
7 reproductive system MP:0005389 9.63 APOE BCL2 CHAT LBR PRL THBD
8 respiratory system MP:0005388 9.43 APOE CHAT ENO2 IL2RA LBR THBD
9 vision/eye MP:0005391 9.02 APOE BCL2 CHAT IL2RA LBR

Drugs & Therapeutics for Head Injury

Drugs for Head Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 565)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 2,Not Applicable 50-78-2 2244
2
Galantamine Approved Phase 4,Phase 2 357-70-0 9651
3
Zinc Approved, Investigational Phase 4 7440-66-6
4
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 69-65-8 453 6251
5
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
6
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 57-27-2 5288826
7 tannic acid Approved Phase 4,Phase 2,Phase 1,Not Applicable
8
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 2078-54-8 4943
9
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
10
Sufentanil Approved, Investigational Phase 4,Phase 2 56030-54-7 41693
11
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
12
Sevoflurane Approved, Vet_approved Phase 4,Phase 2 28523-86-6 5206
13
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 113775-47-6 68602 5311068
14
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 51-61-6, 62-31-7 681
15
Methylphenidate Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 113-45-1 4158
16
Atracurium Approved, Experimental, Investigational Phase 4,Not Applicable 64228-79-1 47319
17
Cisatracurium Approved Phase 4 96946-41-7
18
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1 1197-18-8 5526
19
Amantadine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 768-94-5 2130
20
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
21
Citalopram Approved Phase 4,Not Applicable 59729-33-8 2771
22
Norepinephrine Approved Phase 4,Phase 2,Not Applicable 51-41-2 439260
23
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-84-3 187
24
Acetaminophen Approved Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
25
Ethanol Approved Phase 4,Phase 3,Phase 2,Not Applicable 64-17-5 702
26
Enoxaparin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 9005-49-6 772
27
Ibuprofen Approved Phase 4,Phase 2,Not Applicable 15687-27-1 3672
28
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
29
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 1177-87-3
30
Thiopental Approved, Vet_approved Phase 4,Phase 3 76-75-5 3000715
31
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
32
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 1 525-66-6 4946
33
Exenatide Approved, Investigational Phase 4,Not Applicable 141758-74-9 15991534
34
Testosterone Approved, Investigational Phase 4,Not Applicable 58-22-0 6013
35
Methyltestosterone Approved Phase 4 58-18-4 6010
36
Testosterone enanthate Approved Phase 4 315-37-7 9416
37
Testosterone undecanoate Approved, Investigational Phase 4 5949-44-0
38
Simvastatin Approved Phase 4 79902-63-9 54454
39
Quinidine Approved, Investigational Phase 4,Phase 2 56-54-2 441074
40
Dextromethorphan Approved Phase 4,Phase 3 125-71-3 5360696 5362449
41
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 2 93-14-1 3516
42
Topiramate Approved Phase 4,Early Phase 1 97240-79-4 5284627
43
Caffeine Approved Phase 4,Not Applicable 58-08-2 2519
44
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 57-41-0 1775
45 Piracetam Approved, Investigational Phase 4,Phase 3,Phase 2 7491-74-9
46
Fosphenytoin Approved, Investigational Phase 4,Phase 3,Not Applicable 93390-81-9 56339
47
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
48
Polyestradiol phosphate Approved Phase 4,Not Applicable 28014-46-2
49
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
50 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Not Applicable 979-32-8

Interventional clinical trials:

(show top 50) (show all 1704)
# Name Status NCT ID Phase Drugs
1 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4 discontinuation of aspirin therapy;continuation of aspirin therapy
2 Oxepa in Multiple Trauma Unknown status NCT01099501 Phase 4
3 Galantamine in the Treatment of Post-Traumatic Headache Unknown status NCT00219869 Phase 4 Galantamine
4 Lactate and Hypoglycemia Unknown status NCT01387477 Phase 4 Lactate;Glucose
5 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
6 NIMIP: Non Invasive Measurement of the Intracranial Pressure Unknown status NCT01685450 Phase 4
7 Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture Unknown status NCT00829725 Phase 4
8 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4 Insulin
9 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4 Midazolam;Placebo
10 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4 Cerebrolysin;0.9% NaCl, saline
11 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4 Ramelteon
12 The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery Unknown status NCT02123355 Phase 4 Induction of anesthesia;Sevoflurane, remifentanil ,vecuronium;Dexmedetomidine;Placebo
13 Methylphenidate for Attention Problems After Pediatric TBI Unknown status NCT01933217 Phase 4 Methylphenidate;Placebo
14 Efficiency of a Small-peptide Enteral Feeding Formula Compared to a Whole-protein Formula Unknown status NCT01833624 Phase 4
15 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
16 A Study on the Safety of Tranexamic Acid for the Chronic Subdural Hematoma Population Unknown status NCT02618382 Phase 4 Tranexamic Acid
17 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4 Amantadine hydrochloride;Placebo capsule
18 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4 Insulin (Actrapid)
19 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4 Diclofenac
20 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
21 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4 citalopram;Placebo
22 Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients Completed NCT03480880 Phase 4
23 Enteral Glutamine in Neurologically-injured Patients Completed NCT00204971 Phase 4
24 Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients Completed NCT00204958 Phase 4 nutritional supplement;glutamine popsicle
25 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4 citalopram (celexa)
26 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4 Rivastigmine
27 NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit Completed NCT01685476 Phase 4
28 Using Propranolol in Traumatic Brain Injury to Reduce Sympathetic Storm Phenomenon Completed NCT03401515 Phase 4 Propranolol Hydrochloride 1 MG/ML
29 Beta Blockade in in Traumatic Brain Injury Completed NCT02957331 Phase 4 Propranolol
30 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
31 Intravenous Exenatide in Patients With Acute Brain Injury Completed NCT02058940 Phase 4 Exenatide
32 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4 Methylphenidate;Placebo
33 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4 Androgel (Testosterone Gel);Androgel Placebo
34 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4 methylphenidate
35 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4 Dipeptiven
36 Simvastatin for mTBI Completed NCT01952288 Phase 4 simvastatin;Placebo Oral Tablet
37 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4 Venlafaxine
38 Myobloc Atrophy Study Completed NCT02052024 Phase 4 Botox;MYOBLOC
39 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4 Intravenous acetaminophen;Placebo for IV acetaminophen
40 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4 Nuedexta (DM 20 mg/Q 10 mg)
41 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4 Topiramate;Placebo
42 Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis Completed NCT03048383 Phase 4 OnabotulinumtoxinA Injectable Product;AbobotulinumtoxinA Injectable Product;Incobotulinumtoxin A Injectable Product
43 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4 Recombinant human growth hormone
44 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
45 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4 Levetiracetam;Phenytoin
46 Study of Ocular Penetration of Topically Administered Fluoroquinolones Completed NCT00924729 Phase 4 Moxifloxacin 0.5% ophthalmic solution;Besifloxacin 0.6% ophthalmic suspension
47 Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity Completed NCT00178646 Phase 4 Botox
48 The Use of Low Molecular Weight Heparin in Traumatic Brain Injury Completed NCT00170378 Phase 4 Enoxaparin
49 Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery Recruiting NCT03564886 Phase 4 Hyperosmolar Saline;Normal saline
50 Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates? Recruiting NCT03054285 Phase 4 Levetiracetam

Search NIH Clinical Center for Head Injury

Genetic Tests for Head Injury

Anatomical Context for Head Injury

MalaCards organs/tissues related to Head Injury:

41
Brain, Testes, Eye, Bone, Liver, Pituitary, Heart

Publications for Head Injury

Articles related to Head Injury:

(show top 50) (show all 2342)
# Title Authors Year
1
Survival analysis-based human head injury risk curves: focus on skull fracture. ( 29409390 )
2018
2
Induced neural stem cell-derived astrocytes modulate complement activation and mediate neuroprotection following closed head injury. ( 29367701 )
2018
3
The Epidemiology of Pediatric Head Injury Treated Outside of Hospital Emergency Departments. ( 29240568 )
2018
4
Bilateral medial rectus palsy due to midbrain infarction following concussion head injury. ( 29283153 )
2018
5
Clinicopathological Characteristics of Traumatic Head Injury in Juvenile, Middle-Aged and Elderly Individuals. ( 29773781 )
2018
6
Italian guidelines on the assessment and management of pediatric head injury in the emergency department. ( 29334996 )
2018
7
Can tackle height influence head injury assessment risk in elite rugby union? ( 29801755 )
2018
8
Does ball carrier technique influence tackler head injury assessment risk in elite rugby union? ( 29969061 )
2018
9
Serum S100B Levels Can Predict Computed Tomography Findings in Paediatric Patients with Mild Head Injury. ( 29850551 )
2018
10
Comments on "Bilateral medial rectus palsy due to midbrain infarction following concussion head injury". ( 29941773 )
2018
11
Pediatric Nonmissile Penetrating Head Injury: Case Series and Literature Review. ( 29155117 )
2018
12
Predictors Associated With Post-Traumatic Hydrocephalus in Patients With Head Injury Undergoing Unilateral Decompressive Craniectomy. ( 29867743 )
2018
13
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. ( 29360998 )
2018
14
A Novel Approach to Assessing Head Injury Severity in Pediatric Patient Falls. ( 29277473 )
2018
15
Multiple Pediatric Head Injury Decision Rules but What Should the Clinician Use? ( 29971851 )
2018
16
Headache following head injury: a population-based longitudinal cohort study (HUNT). ( 29356960 )
2018
17
Cerebral Microcirculation and Histological Mapping After Severe Head Injury: A Contusion and Acceleration Experimental Model. ( 29867710 )
2018
18
Calculated Decisions: PECARN Pediatric Head Injury/Trauma Algorithm ( 29893520 )
2018
19
Pediatric dural venous sinus thrombosis following closed head injury: an easily overlooked diagnosis with devastating consequences. ( 29350373 )
2018
20
Physicians' Risk Tolerance and Head Computed Tomography Use for Pediatric Patients With Minor Head Injury. ( 29847541 )
2018
21
Direct head injury caused by a tear gas cartridge. Questions on safety: A case report from Iraq and review of the literature. ( 29980474 )
2018
22
Does a regular Wessex Head Injury Matrix assessment identify early signs of infections in people with Prolonged Disorders of Consciousness? ( 29894208 )
2018
23
Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury. ( 29238428 )
2018
24
A Pilot Study to Reduce Computed Tomography Utilization for Pediatric Mild Head Injury in the Emergency Department Using a Clinical Decision Support Tool and a Structured Parent Discussion Tool. ( 29768294 )
2018
25
Otopathologic Changes in the Cochlea following Head Injury without Temporal Bone Fracture. ( 29890895 )
2018
26
Incidence, course and risk factors of head injury: a retrospective cohort study. ( 29858414 )
2018
27
Delayed hemiparkinsonism after closed head injury. ( 29364398 )
2018
28
Trial of life: Well infants presenting more than 24 h after head injury with a scalp haematoma: A 10-year review. ( 29748981 )
2018
29
Minocycline plus N-acetylcysteine protect oligodendrocytes when first dosed 12 hours after closed head injury in mice. ( 29885452 )
2018
30
Application of the Canadian Computed Tomography Head Rule to Patients With Minimal Head Injury. ( 29753518 )
2018
31
Nicotine-induced Conditional Place Preference is Affected by Head Injury: Correlation with Dopamine Release in the Nucleus Accumbens Shell. ( 29905798 )
2018
32
Health-related quality of life in prisoners with attention-deficit hyperactivity disorder and head injury. ( 29929487 )
2018
33
Risk of mild head injury in preschool children: relationship to attention deficit hyperactivity disorder symptoms. ( 29696355 )
2018
34
Parent-Reported Mild Head Injury History in Children: Long-Term Effects on Attention-Deficit Hyperactivity Disorder. ( 29511708 )
2018
35
Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture. ( 30274548 )
2018
36
Septic Cavernous Sinus Thrombosis Following a Minor Head Injury: A Rare Cause of Medico-Legal Death. ( 29464700 )
2018
37
Posterior Reversible Encephalopathy Syndrome and Guillain-Barré Syndrome after Head Injury: Case Report. ( 30078819 )
2018
38
Therapeutic effect of a novel fatty acid amide hydrolase inhibitor PF04457845 in the repetitive closed head injury mouse model. ( 30526351 )
2018
39
Assessing photoreceptor structure in patients with traumatic head injury. ( 30539149 )
2018
40
Audit of Paediatric Head Injury in University Hospital Kerry ( 30556676 )
2018
41
Repetitive Mild Closed Head Injury Alters Protein Expression and Dendritic Complexity in a Mouse Model. ( 28701108 )
2018
42
The Effect of Tackler Technique on Head Injury Assessment Risk in Elite Rugby Union. ( 29049096 )
2018
43
Prevalence of Head Injury and Associated Disability in Prison Populations: A Systematic Review. ( 29084104 )
2018
44
Prediction of Poor Prognosis After Severe Head Injury in Children Using Logistic Regression. ( 29095390 )
2018
45
A Time Limit for Initiating Anti-Inflammatory Treatment for Improved Olfactory Function after Head Injury. ( 29117762 )
2018
46
Evaluation of the Roche® Elecsys and the Diasorin® Liaison S100 kits in the management of mild head injury in the emergency room. ( 29122642 )
2018
47
Head injury profoundly affects gut microbiota homeostasis: Results of a pilot study. ( 29129229 )
2018
48
Head injury mechanisms in FIS World Cup alpine and freestyle skiers and snowboarders. ( 29133295 )
2018
49
Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study. ( 29452747 )
2018
50
Is Mechanical Ventilation Mandatory for the Management of Severe Head Injury? Outcome in 53 Medically Managed Severe Head Injury Patients, Without Ventilatory Support: A Prospective Study. ( 29492115 )
2018

Variations for Head Injury

Expression for Head Injury

Search GEO for disease gene expression data for Head Injury.

Pathways for Head Injury

Pathways related to Head Injury according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 APOE ENO2 S100B
2
Show member pathways
11.16 BCL2 IL2RA PRL

GO Terms for Head Injury

Cellular components related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 APOE ENO2 PRL S100B THBD

Biological processes related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.46 BCL2 IL2RA PRL S100B
2 cholesterol biosynthetic process GO:0006695 9.43 APOE LBR
3 negative regulation of endothelial cell proliferation GO:0001937 9.4 APOE PRL
4 T cell homeostasis GO:0043029 9.37 BCL2 IL2RA
5 regulation of neuronal synaptic plasticity GO:0048168 9.32 APOE S100B
6 negative regulation of blood coagulation GO:0030195 9.26 APOE THBD
7 female pregnancy GO:0007565 9.13 BCL2 PRL THBD
8 negative regulation of platelet activation GO:0010544 8.62 APOE THBD

Molecular functions related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tau protein binding GO:0048156 8.62 APOE S100B

Sources for Head Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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