MCID: HDN002
MIFTS: 45

Head Injury

Categories: Neuronal diseases

Aliases & Classifications for Head Injury

Summaries for Head Injury

MedlinePlus : 42 Chances are you've bumped your head before. Often, the injury is minor because your skull is hard and it protects your brain. But other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. Head injuries can be open or closed. A closed injury does not break through the skull. With an open, or penetrating, injury, an object pierces the skull and enters the brain. Closed injuries are not always less severe than open injuries. Some common causes of head injuries are falls, motor vehicle accidents, violence, and sports injuries. It is important to know the warning signs of a moderate or severe head injury. Get help immediately if the injured person has A headache that gets worse or does not go away Repeated vomiting or nausea Convulsions or seizures An inability to wake up Dilated (enlarged) pupil in one or both eyes Slurred speech Weakness or numbness in the arms or legs Loss of coordination Increased confusion, restlessness, or agitation Doctors use a neurologic exam and imaging tests to make a diagnosis. Treatment depends on the type of injury and how severe it is. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Head Injury, also known as head injuries, is related to traumatic brain injury and intracranial cysts. An important gene associated with Head Injury is APOE (Apolipoprotein E), and among its related pathways/superpathways are JAK-STAT signaling pathway (KEGG) and Neuroscience. The drugs Galantamine and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and bone, and related phenotypes are behavior/neurological and homeostasis/metabolism

NINDS : 53 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Wikipedia : 74 A head injury is any injury that results in trauma to the skull or brain. The terms traumatic brain... more...

Related Diseases for Head Injury

Diseases related to Head Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 572)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.8 S100B ENO2 APOE
2 intracranial cysts 32.0 S100B ENO2
3 hydrocephalus 31.3 S100B PRL ENO2 APOE
4 amnestic disorder 31.2 S100B CHAT APOE
5 persistent vegetative state 31.0 ENO2 APOE
6 brain injury 30.8 S100B ENO2 APOE
7 cardiac arrest 30.2 S100B ENO2 APOE
8 papilloma of choroid plexus 29.7 S100B ENO2
9 spondylosis 29.7 S100B ENO2
10 obstructive hydrocephalus 29.5 PRL ENO2
11 supranuclear palsy, progressive, 1 29.4 SOD1 CHAT APOE
12 tetanus 29.3 SOD1 LBR IL2RA
13 vascular dementia 29.2 SOD1 CHAT APOE
14 paranoid schizophrenia 29.1 S100B PRL
15 schizophrenia 28.1 SOD1 S100B PRL CHAT APOE
16 end stage renal failure 27.8 SOD1 PRL LBR IL2RA
17 seizure disorder 11.5
18 arachnoid cysts, intracranial 11.5
19 headache 11.4
20 aphasia 11.4
21 epilepsy 11.4
22 dementia pugilistica 11.4
23 cerebral palsy 11.3
24 hyperacusis 11.3
25 leukoencephalopathy, hereditary diffuse, with spheroids 11.3
26 lennox-gastaut syndrome 11.2
27 ocular motor apraxia 11.1
28 diabetes insipidus, neurohypophyseal 11.0
29 intracranial hypertension 10.8
30 rare surgical neurologic disease 10.7
31 brain edema 10.6
32 visual epilepsy 10.5
33 hydrops, lactic acidosis, and sideroblastic anemia 10.5
34 thrombosis 10.4
35 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.4
36 meningitis 10.3
37 spinal cord injury 10.3
38 disseminated intravascular coagulation 10.3
39 bednar tumor 10.3 S100B ENO2
40 diabetes insipidus 10.3
41 encephalopathy 10.3
42 meningeal melanocytoma 10.3 S100B ENO2
43 papillary ependymoma 10.3 S100B ENO2
44 pineocytoma 10.3 S100B ENO2
45 post-cardiac arrest syndrome 10.3 S100B ENO2
46 akinetic mutism 10.3 S100B ENO2
47 ossifying fibromyxoid tumor 10.3 S100B ENO2
48 extraosseous ewing sarcoma 10.3 S100B ENO2
49 senile plaque formation 10.3 CHAT APOE
50 alzheimer disease 10.3

Graphical network of the top 20 diseases related to Head Injury:



Diseases related to Head Injury

Symptoms & Phenotypes for Head Injury

MGI Mouse Phenotypes related to Head Injury:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.11 APOE BCL2 CHAT ENO2 IL2RA LBR
2 homeostasis/metabolism MP:0005376 9.97 APOE BCL2 CHAT IL2RA LBR PRL
3 endocrine/exocrine gland MP:0005379 9.88 APOE BCL2 IL2RA LBR PRL SOD1
4 digestive/alimentary MP:0005381 9.83 APOE BCL2 CHAT IL2RA LBR
5 integument MP:0010771 9.8 APOE BCL2 LBR PRL S100B SOD1
6 nervous system MP:0003631 9.8 APOE BCL2 CHAT ENO2 LBR PRL
7 reproductive system MP:0005389 9.63 APOE BCL2 CHAT LBR PRL SOD1
8 respiratory system MP:0005388 9.35 APOE CHAT ENO2 IL2RA LBR
9 vision/eye MP:0005391 9.1 APOE BCL2 CHAT IL2RA LBR SOD1

Drugs & Therapeutics for Head Injury

Drugs for Head Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 219)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Galantamine Approved Phase 4 357-70-0 9651
2
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
4
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
5 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
6
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
7
Thiopental Approved, Vet_approved Phase 4 76-75-5 3000715
8
Levetiracetam Approved Phase 4 102767-28-2 441341
9
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
11
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
12
Acetaminophen Approved Phase 4 103-90-2 1983
13
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
14
Naratriptan Approved, Investigational Phase 4 143388-64-1, 121679-13-8 4440
15
Perphenazine Approved Phase 4 58-39-9 4748
16
Topiramate Approved Phase 4 97240-79-4 5284627
17
Propranolol Approved, Investigational Phase 4 525-66-6 4946
18
Amitriptyline Approved Phase 4 50-48-6 2160
19
Ibuprofen Approved Phase 4 15687-27-1 3672
20
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
21
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
22
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
23
Ornithine Approved, Nutraceutical Phase 4 70-26-8, 3184-13-2 6262
24
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
25
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
26
Coumarin Experimental Phase 4 91-64-5 323
27 Autonomic Agents Phase 4
28 Protective Agents Phase 4
29 Antiemetics Phase 4
30 Gastrointestinal Agents Phase 4
31 Neuroprotective Agents Phase 4
32 Methylprednisolone Acetate Phase 4
33 Antineoplastic Agents, Hormonal Phase 4
34 glutamine Phase 4
35 Pharmaceutical Solutions Phase 4
36 Liver Extracts Phase 4
37 N-Methylaspartate Phase 4
38 Excitatory Amino Acid Agonists Phase 4
39 Excitatory Amino Acid Antagonists Phase 4
40 Excitatory Amino Acids Phase 4
41 Anesthetics, Dissociative Phase 4
42 Narcotics Phase 4
43 Analgesics, Opioid Phase 4
44 Iron-Dextran Complex Phase 4
45 Vasoconstrictor Agents Phase 4
46 Neurotransmitter Agents Phase 4
47 Tranquilizing Agents Phase 4
48 GABA Agents Phase 4
49 Psychotropic Drugs Phase 4
50 Anticonvulsants Phase 4

Interventional clinical trials:

(show top 50) (show all 367)
# Name Status NCT ID Phase Drugs
1 Galantamine in the Preventive Treatment of Chronic Post-Traumatic Headache Unknown status NCT00219869 Phase 4 Galantamine
2 Comparison of Two Strategies of Hypoglycemia Correction in ICU Unknown status NCT01387477 Phase 4 Lactate;Glucose
3 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4 discontinuation of aspirin therapy;continuation of aspirin therapy
4 Evaluation of High-dose Corticosteroids on Microcirculation Alterations in Cardiac Surgery, by FMD (Flow Mediated vasoDilation), Near Infrared Spectrophotometry (NIRS) and Biological Analysis (Syndecan-1) Unknown status NCT02798068 Phase 4 Solu-medrol or placebo administration
5 Randomized, Placebo-controlled Clinical Trial of Enteral Glutamine Supplementation in Neurologically-injured Patients Completed NCT00204971 Phase 4
6 Evaluation of Glutamine Popsicles in Adult/Pediatric Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients Completed NCT00204958 Phase 4 nutritional supplement;glutamine popsicle
7 Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients Completed NCT03480880 Phase 4
8 a Randomized Clinical Trial Using Oral Anti Coagulant in the Management of Unexplained Oligohydramnios Completed NCT01569035 Phase 4 warfarin
9 Efficacy of Intravenous 'L-ornithine L-aspartate' in Reversal of Overt Acute Hepatic Encephalopathy in Patients With Liver Cirrhosis: a Prospective, Randomized, Double-blind, Placebo Controlled Trial Completed NCT01722578 Phase 4 L-ornithine L-aspartate;Placebo
10 Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates? Recruiting NCT03054285 Phase 4 Levetiracetam
11 Comparison of Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED: A Prospective, Randomized Double-Blind Trial Recruiting NCT03950817 Phase 4 Nebulized Sub-dissociative Dose Ketamine at either 0.75 mg/kg;Nebulized Sub-dissociative Dose Ketamine at 1 mg/kg;Nebulized Sub-dissociative Dose Ketamine at 1.5 mg/kg.
12 A Randomized Controlled Trial of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture at Triage (CAST Trial) Not yet recruiting NCT02985177 Phase 4 Fentanyl intranasal + Oral Hydromorphone;Fentanyl intranasal + Oral ibuprofen
13 Head Trauma With Traumatic Brain Injury (TBI): A Multicenter, Phase IV Study to Evaluate the Effects of Genotropin in Adult Patients With Growth Hormone Deficiency (GHD) Caused by Trauma and/or Head Injury Terminated NCT00638053 Phase 4
14 Effects of Intrathoracic Pressure Regulation Therapy in Patients With Elevated Intracranial Pressure Due to Brain Injury or Intracranial Pathology Terminated NCT01824589 Phase 4
15 Evaluation of the Efficacy of Naratriptan for the Treatment and Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction Terminated NCT00487578 Phase 4 naratriptan HCl
16 A Randomized Controlled Trial of Medical Therapies for Chronic Post-Traumatic Headaches Terminated NCT00862095 Phase 4 Placebo;Propranolol;Amitriptyline;Topiramate
17 Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage Terminated NCT01530880 Phase 4 Intravenous Ibuprofen;Acetaminophen (Standard of Care)
18 Exploring the Use of Transdermal Methylphenidate to Reduce Fall Risk in Patients With Dementia. Terminated NCT01825577 Phase 4 Transdermal Methylphenidate
19 Propofol Versus Midazolam for Sedation in Mechanically Ventilated Critically Ill Patients Who Presented With Traumatic Brain Injury: Cytokine Response and Neuropsychological Assessment (IRRC#1201M) Terminated NCT01712477 Phase 4 Intravenous sedation using propofol;Intravenous sedation with midazolam
20 School Playground Surfacing - A Randomized Prospective Comparison of Injury Rates on Sand Versus Wood Chip Surfaces Unknown status NCT00213174 Phase 3
21 High Dose Hyperoncotic Serum Albumin for the Treatment of the Acute Phase of Severe Head Injury Unknown status NCT00152685 Phase 2, Phase 3 human serum albumin
22 Traumatic Brain Injury in Latin America: Lifespan Analysis Unknown status NCT01068522 Phase 3
23 A Prospective Multicenter Double Blind Randomized Controlled Trial to Explore the Tolerability, Safety and Efficacy of the H1-Coil Deep Transcranial Magnetic Stimulation (TMS) in Subjects With Schizophrenia Experiencing Auditory Hallucinations Unknown status NCT00564096 Phase 2, Phase 3
24 The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial Completed NCT00878631 Phase 2, Phase 3 hypertonic saline mixed with dextran;Normal Saline
25 Multicenter Trial of CPE for Maxillofacial Prosthetics Completed NCT00123097 Phase 3
26 Evaluation of an Active Strategy to Implement the Canadian CT Head Rule: Phase III Completed NCT00993252 Phase 3
27 Magnesium Sulfate for Neuroprotection After Brain Trauma Completed NCT00004730 Phase 3 magnesium sulfate
28 Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures Completed NCT00004817 Phase 3 phenytoin;valproate sodium
29 The Toronto Prehospital Hypertonic Resuscitation-Head Injury and Multi Organ Dysfunction Trial Completed NCT01642524 Phase 3
30 Efficacy and Safety Evaluation of a Single Intravenous Dose of Dexanabinol in Patients Suffering From Severe Traumatic Brain Injury Completed NCT00129857 Phase 3 Dexanabinol
31 Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression & Other Neuropsychiatric Symptoms After Traumatic Brain Injury (TBI) Completed NCT02367521 Phase 2, Phase 3
32 Effect of Preventive Sodium Lactate Infusion on Intracranial Hypertension in Severe Trauma Tic Brain Injury Completed NCT00995683 Phase 2, Phase 3 half molar sodium lactate;isotonic sodium chloride
33 CRISTAL: Colloids Compared to Crystalloids in Fluid Resuscitation of Critically Ill Patients: A Multinational Randomised Controlled Trial Completed NCT00318942 Phase 3 Crystalloids;Colloids;Crystalloids;Colloids
34 Efficacy of Albumin Administration for Volume Replacement in Patients With Severe Sepsis or Septic Shock - the ALBumin Italian Outcome Sepsis (ALBIOS) Study Completed NCT00707122 Phase 3
35 Early N-Acetyl Cysteine Treatment for Head Trauma-induced Anosmia Recruiting NCT03680911 Phase 3 N Acetyl Cysteine;Placebo oral capsule
36 PROTEST Trial - PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury, a Double-blind Randomized Controlled Trial Recruiting NCT03559114 Phase 3 Dalteparin;Saline
37 Respiratory Mechanics Following Brain Injury: The Role of Inhaled Nitric Oxide Recruiting NCT03260569 Phase 3 Inhaled Nitric Oxide;Placebo
38 Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients With Traumatic Brain Injury Recruiting NCT02504866 Phase 3
39 Salovum (Antisecretory Factor) in Patients With Severe Traumatic Brain Injury Recruiting NCT03339505 Phase 3
40 Randomized Trial of a Multifactorial Fall Injury Prevention Strategy Active, not recruiting NCT02475850 Phase 3
41 Interest of Oral Corticosteroids in the Treatment of Chronic Subdural Hematomas. Prospective Randomized Multicenter Trial Active, not recruiting NCT01380028 Phase 3 oral corticosteroids;placebo
42 A Randomised, Double-blind, Placebo-controlled Trial on the Efficacy of Atorvastatin in Chronic Subdural Haematoma (The REACH Study) Not yet recruiting NCT03956368 Phase 3 Atorvastatin 20mg;Placebos
43 Pilot Optimizing Transfusion Thresholds in Critically-ill Children With Anaemia (P-OpTTICCA): a Pilot Trial for a Large Pragmatic International Parallel Open-label Non-inferiority Randomised Controlled Trial. Not yet recruiting NCT03871244 Phase 3
44 Metformin in Alzheimer's Dementia Prevention Not yet recruiting NCT04098666 Phase 2, Phase 3 Placebo oral tablet;extended release metformin
45 Dantrolene as a Treatment for Hyperthermia in Patients After Subarachnoidal Hemorrhage Terminated NCT00796900 Phase 2, Phase 3 Dantrolene;Placebo
46 Intérêt d'Utiliser Des solutés de Remplissage équilibrés à la Phase précoce d'un Traumatisme crânien Grave Pour Limiter l'Acidose hyperchlorémique Terminated NCT00847977 Phase 3 use of a non balced fluid and of a macromolecular fluid;use of balanced crystalloids fluid and macromolecular fluid
47 The Use of Non Invasive Brain Stimulation in the Treatment of the Sequelae of Closed Brain Injury Unknown status NCT00531258 Phase 2
48 Phase 1/2 Multicenter, Randomized, Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury Unknown status NCT00810940 Phase 1, Phase 2 AbelaDrug200;mannitol
49 Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study Unknown status NCT02232347 Phase 2 Ketamine;Sufentanil
50 Changes in Morphine Handling and Response in Patients With Brain Trauma Unknown status NCT00196131 Phase 1, Phase 2 morphine

Search NIH Clinical Center for Head Injury

Genetic Tests for Head Injury

Anatomical Context for Head Injury

MalaCards organs/tissues related to Head Injury:

40
Brain, Testes, Bone, Eye, Pituitary, Spinal Cord, Heart

Publications for Head Injury

Articles related to Head Injury:

(show top 50) (show all 22214)
# Title Authors PMID Year
1
Surfing-related head injuries presenting to United States emergency departments. 61
32025130 2020
2
N-butyl cyanoacrylate embolization of a traumatic pseudoaneurysm and arteriovenous fistula of the middle meningeal artery. 61
31993092 2020
3
A novel mouse model for the study of endogenous neural stem and progenitor cells after traumatic brain injury. 61
31751572 2020
4
Unplanned Complex Suicide by Self-Stabbing and Rail Suicide: A Case Report and Review of Literature. 61
32022760 2020
5
Juvenile mild traumatic brain injury elicits distinct spatiotemporal astrocyte responses. 61
31670865 2020
6
Sustained neuronal and microglial alterations are associated with diverse neurobehavioral dysfunction long after experimental brain injury. 61
31843705 2020
7
Acute Sports-Related Head Injuries. 61
32014133 2020
8
Current status of infarction in the basal ganglia-internal capsule due to mild head injury in children using PRISMA guidelines. 61
32010282 2020
9
Sports-related concussion (SRC) in road cycling: the RoadsIde heaD Injury assEssment (RIDE) for elite road cycling. 61
31653774 2020
10
Comparison between postmortem computed tomography and autopsy in the detection of traumatic head injuries. 61
30954548 2020
11
Interferon-β plays a detrimental role in experimental traumatic brain injury by enhancing neuroinflammation that drives chronic neurodegeneration. 61
32029532 2020
12
Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injury. 61
31730763 2020
13
Examining the "reading the mind in the eyes test" as an assessment of subtle differences in affective theory of mind after concussion. 61
31107147 2020
14
Association Between Neurological Disorders and Death by Suicide in Denmark. 61
32016308 2020
15
Exploring naturally occurring clinical subgroups of post-traumatic headache. 61
32033526 2020
16
Reverse shock index multiplied by Glasgow Coma Scale (rSIG) predicts mortality in severe trauma patients with head injury. 61
32034233 2020
17
Inflicted versus unintentional injury: towards improved detection and surveillance of supervisory neglect. 61
31784100 2020
18
Incidence and outcome of traumatic brain injury in paediatric population of Bosnia and Herzegovina: a single centre experience. 61
31845565 2020
19
Degree of hyperglycemia independently associates with hospital mortality and length of stay in critically ill, nondiabetic patients: Results from the ANZICS CORE binational registry. 61
31731174 2020
20
Epidemiology of paediatric injuries in Rwanda using a prospective trauma registry. 61
32011812 2020
21
Incidence of intracranial bleeding in seniors presenting to the emergency department after a fall: A systematic review. 61
31901331 2020
22
A profile of traumatic injury in the prehospital setting in India: A prospective observational study across seven states. 61
31761424 2020
23
Baseline Performance of Real-World Clinical Practice Within a Statewide Emergency Medicine Quality Network: The Michigan Emergency Department Improvement Collaborative (MEDIC). 61
31256906 2020
24
Combat exposure, posttraumatic stress disorder, and head injuries differentially relate to alterations in cortical thickness in military Veterans. 61
31600766 2020
25
Checklist for Head Injury Management Evaluation Study (CHIMES): a quality improvement initiative to reduce imaging utilisation for head injuries in the emergency department. 61
32019751 2020
26
Intent of health care providers to adopt a clinical decision support tool in the management of minor pediatric head injuries. 61
30951010 2020
27
Neuropsychological functioning in ageing retired NFL players: a critical review. 61
31592681 2020
28
Age differences in outcome after mild traumatic brain injury: results from the HeadSMART study. 61
31549522 2020
29
Age, symptoms, and functional outcome after mild traumatic brain injury. 61
31693184 2020
30
Psychosocial health of patients receiving orthopaedic treatment in northern Tanzania: A cross-sectional study. 61
32021686 2020
31
Integrating program-tailored universal trauma screening into HIV care: an evidence-based participatory approach. 61
31357876 2020
32
Effects of Exergaming on Balance of Healthy Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. 61
31800322 2020
33
Falls from height due to accident and suicide attempt in Greece. A comparison of the injury patterns. 61
31902573 2020
34
The effect of age of first exposure to competitive fighting on cognitive and other neuropsychiatric symptoms and brain volume. 61
31587599 2020
35
Outcomes following resuscitative thoracotomy for abdominal exsanguination, a systematic review. 61
32028977 2020
36
EXTRA-PERITONEAL PACKING IN UNSTABLE BLUNT PELVIC TRAUMA: A SINGLE-CENTER STUDY. 61
32032281 2020
37
MRI Is Better Than CT Scan for Detection of Structural Pathologies After Traumatic Posterior Hip Dislocations in Children and Adolescents. 61
31923168 2020
38
Photobiomodulation therapy for repeated closed head injury in rats. 61
31657525 2020
39
Predicting orbital fractures in head injury: a preliminary study of clinical findings. 61
31471701 2020
40
Sensitivity analysis of muscle properties and impact parameters on head injury risk in American football. 61
31982110 2020
41
Pediatric minor head injury imaging practices: results from an ESPR survey. 61
31828360 2020
42
Does the CATCH clinical decision rule adequately determine which children with minor head injury require computed tomography (CT) imaging? 61
31769375 2020
43
Head injury metric response in finite element ATDs and a human body model in multidirectional loading regimes. 61
31951749 2020
44
[Symptomatic hyponatremia in a 43-year-old woman after a skiing accident with head injuries]. 61
31673730 2020
45
Effect of motorcycle helmet types on head injuries: evidence from eight level-I trauma centres in Taiwan. 61
31952485 2020
46
What types of injuries did seriously injured pedestrians and cyclists receive in a Swedish urban region in the time period 2003-2017 when Vision Zero was implemented? 61
31954870 2020
47
Equivalent inpatient mortality among direct-acting oral anticoagulant and warfarin users presenting with major hemorrhage. 61
31794885 2020
48
Validation of the scandinavian guidelines for initial management of minor and moderate head trauma in children. 61
31907552 2020
49
Long-term cognitive impairment following single mild traumatic brain injury with loss of consciousness: Findings from the Canadian Longitudinal Study on Aging. 61
31984839 2020
50
Effects of Vasopressors on Cerebral Circulation and Oxygenation: A Narrative Review of Pharmacodynamics in Health and Traumatic Brain Injury. 61
30950915 2020

Variations for Head Injury

Expression for Head Injury

Search GEO for disease gene expression data for Head Injury.

Pathways for Head Injury

Pathways related to Head Injury according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.5 PRL IL2RA BCL2
2 11.46 SOD1 S100B ENO2 APOE

GO Terms for Head Injury

Cellular components related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 8.92 SOD1 S100B ENO2 APOE

Biological processes related to Head Injury according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 thymus development GO:0048538 9.55 SOD1 BCL2
2 negative regulation of endothelial cell proliferation GO:0001937 9.54 PRL APOE
3 negative regulation of neuron apoptotic process GO:0043524 9.54 SOD1 BCL2 APOE
4 ovarian follicle development GO:0001541 9.52 SOD1 BCL2
5 reactive oxygen species metabolic process GO:0072593 9.51 SOD1 BCL2
6 T cell homeostasis GO:0043029 9.49 IL2RA BCL2
7 regulation of mitochondrial membrane potential GO:0051881 9.48 SOD1 BCL2
8 cell aging GO:0007569 9.46 SOD1 BCL2
9 regulation of multicellular organism growth GO:0040014 9.43 SOD1 PRL
10 negative regulation of inflammatory response GO:0050728 9.43 SOD1 IL2RA APOE
11 regulation of neuronal synaptic plasticity GO:0048168 9.4 S100B APOE
12 response to oxidative stress GO:0006979 9.33 SOD1 BCL2 APOE
13 response to reactive oxygen species GO:0000302 9.32 SOD1 APOE
14 negative regulation of cholesterol biosynthetic process GO:0045541 8.96 SOD1 APOE
15 positive regulation of catalytic activity GO:0043085 8.8 SOD1 BCL2 APOE

Molecular functions related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.46 SOD1 S100B BCL2 APOE
2 tau protein binding GO:0048156 8.96 S100B APOE
3 antioxidant activity GO:0016209 8.62 SOD1 APOE

Sources for Head Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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