Aliases & Classifications for Head Injury

MalaCards integrated aliases for Head Injury:

Name: Head Injury 53 17
Head Injuries 42

Classifications:



External Ids:

ICD10 32 S09.8 S09.9

Summaries for Head Injury

MedlinePlus : 42 Chances are you've bumped your head before. Often, the injury is minor because your skull is hard and it protects your brain. But other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. Head injuries can be open or closed. A closed injury does not break through the skull. With an open, or penetrating, injury, an object pierces the skull and enters the brain. Closed injuries are not always less severe than open injuries. Some common causes of head injuries are falls, motor vehicle accidents, violence, and sports injuries. It is important to know the warning signs of a moderate or severe head injury. Get help immediately if the injured person has A headache that gets worse or does not go away Repeated vomiting or nausea Convulsions or seizures An inability to wake up Dilated (enlarged) pupil in one or both eyes Slurred speech Weakness or numbness in the arms or legs Loss of coordination Increased confusion, restlessness, or agitation Doctors use a neurologic exam and imaging tests to make a diagnosis. Treatment depends on the type of injury and how severe it is. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Head Injury, also known as head injuries, is related to traumatic brain injury and intracranial cysts. An important gene associated with Head Injury is APOE (Apolipoprotein E), and among its related pathways/superpathways are JAK-STAT signaling pathway and Neuroscience. The drugs Galantamine and Thiopental have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and spinal cord, and related phenotypes are behavior/neurological and homeostasis/metabolism

NINDS : 53 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Wikipedia : 73 A head injury is any injury that results in trauma to the skull or brain. The terms traumatic brain... more...

Related Diseases for Head Injury

Diseases related to Head Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 569)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.3 S100B ENO2 APOE
2 intracranial cysts 31.7 S100B ENO2
3 leukoencephalopathy, hereditary diffuse, with spheroids 31.5 S100B CHAT
4 amnestic disorder 31.4 S100B CHAT APOE
5 persistent vegetative state 31.0 ENO2 APOE
6 brain injury 31.0 S100B ENO2 APOE
7 cerebral palsy 30.7 SOD1 S100B PRL APOE
8 hydrocephalus 30.2 S100B PRL ENO2 APOE
9 spondylosis 29.8 S100B ENO2
10 papilloma of choroid plexus 29.8 S100B ENO2
11 obstructive hydrocephalus 29.8 PRL ENO2
12 supranuclear palsy, progressive, 1 29.7 SOD1 CHAT APOE
13 vascular dementia 29.5 SOD1 CHAT APOE
14 mild cognitive impairment 29.5 SOD1 CHAT APOE
15 paranoid schizophrenia 29.4 S100B PRL
16 disease of mental health 28.1 SOD1 S100B PRL ENO2 CHAT APOE
17 ocular motor apraxia 11.2
18 arachnoid cysts, intracranial 11.1
19 headache 11.1
20 seizure disorder 11.1
21 lennox-gastaut syndrome 11.1
22 aphasia 11.0
23 epilepsy 11.0
24 diabetes insipidus, neurohypophyseal 11.0
25 hyperacusis 10.9
26 intracranial hypertension 10.8
27 brain edema 10.6
28 thrombosis 10.4
29 meningitis 10.4
30 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.4
31 post-traumatic stress disorder 10.4
32 disseminated intravascular coagulation 10.4
33 spinal cord injury 10.4
34 diabetes insipidus 10.4
35 branchiootic syndrome 1 10.4
36 shaken baby syndrome 10.4
37 48,xyyy 10.3
38 dementia pugilistica 10.3
39 whiplash 10.3
40 post-traumatic epilepsy 10.3
41 encephalopathy 10.3
42 kearns-sayre syndrome 10.3
43 cerebral hypoxia 10.3
44 pathologic nystagmus 10.3
45 spasticity 10.3
46 migraine with or without aura 1 10.3
47 yemenite deaf-blind hypopigmentation syndrome 10.3
48 facial paralysis 10.3
49 anisocoria 10.3
50 pulmonary edema 10.3

Graphical network of the top 20 diseases related to Head Injury:



Diseases related to Head Injury

Symptoms & Phenotypes for Head Injury

MGI Mouse Phenotypes related to Head Injury:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.11 APOE BCL2 CHAT ENO2 IL2RA LBR
2 homeostasis/metabolism MP:0005376 9.97 APOE BCL2 CHAT IL2RA LBR PRL
3 endocrine/exocrine gland MP:0005379 9.88 APOE BCL2 IL2RA LBR PRL SOD1
4 digestive/alimentary MP:0005381 9.83 APOE BCL2 CHAT IL2RA LBR
5 integument MP:0010771 9.8 APOE BCL2 LBR PRL S100B SOD1
6 nervous system MP:0003631 9.8 APOE BCL2 CHAT ENO2 LBR PRL
7 reproductive system MP:0005389 9.63 APOE BCL2 CHAT LBR PRL SOD1
8 respiratory system MP:0005388 9.35 APOE CHAT ENO2 IL2RA LBR
9 vision/eye MP:0005391 9.1 APOE BCL2 CHAT IL2RA LBR SOD1

Drugs & Therapeutics for Head Injury

Drugs for Head Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 92)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Galantamine Approved Phase 4 357-70-0 9651
2
Thiopental Approved, Vet_approved Phase 4 76-75-5 3000715
3 Cholinesterase Inhibitors Phase 4
4 Neurotransmitter Agents Phase 4
5 Cholinergic Agents Phase 4
6 Nootropic Agents Phase 4
7 Anesthetics Phase 4
8 Hormones Phase 4
9
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
10
Silicon Approved, Investigational Phase 3 7440-21-3 4082203
11
Nicotinamide Approved, Investigational Phase 3 98-92-0 936
12
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
13
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 3 83-88-5 493570
14
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
15 Analgesics Phase 3
16 Anti-Arrhythmia Agents Phase 3
17 Tocolytic Agents Phase 3
18 Anticonvulsants Phase 3
19 calcium channel blockers Phase 3
20 Calcium, Dietary Phase 3
21 Dextrans Phase 2, Phase 3
22 Plasma Substitutes Phase 2, Phase 3
23 Blood Substitutes Phase 2, Phase 3
24 Antimetabolites Phase 3
25 Hypolipidemic Agents Phase 3
26 Lipid Regulating Agents Phase 3
27 Pharmaceutical Solutions Phase 3
28 Micronutrients Phase 3
29 Vasodilator Agents Phase 3
30 Trace Elements Phase 3
31 Nutrients Phase 3
32 Vitamin B9 Phase 3
33 Folate Phase 3
34 Vitamin B Complex Phase 3
35 Vitamin B3 Phase 3
36 Photosensitizing Agents Phase 3
37 Vitamins Phase 3
38 Vitamin B2 Phase 3
39 Nicotinic Acids Phase 3
40 Dermatologic Agents Phase 3
41
Calcium Nutraceutical Phase 3 7440-70-2 271
42
Morphine Approved, Investigational Phase 1, Phase 2 57-27-2 5288826
43
Mannitol Approved, Investigational Phase 1, Phase 2 69-65-8 453 6251
44
Guaifenesin Approved, Investigational, Vet_approved Phase 2 93-14-1 3516
45
Phenylpropanolamine Approved, Vet_approved, Withdrawn Phase 2 14838-15-4 26934
46 Narcotics Phase 1, Phase 2
47 Analgesics, Opioid Phase 1, Phase 2
48 diuretics Phase 1, Phase 2
49 Neuromuscular Blocking Agents Phase 2
50 Rosuvastatin Calcium Phase 1, Phase 2 147098-20-2

Interventional clinical trials:

(show top 50) (show all 118)
# Name Status NCT ID Phase Drugs
1 Galantamine in the Preventive Treatment of Chronic Post-Traumatic Headache Unknown status NCT00219869 Phase 4 Galantamine
2 Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients Completed NCT03480880 Phase 4
3 Effects of Intrathoracic Pressure Regulation Therapy in Patients With Elevated Intracranial Pressure Due to Brain Injury or Intracranial Pathology Terminated NCT01824589 Phase 4
4 Head Trauma With Traumatic Brain Injury (TBI): A Multicenter, Phase IV Study to Evaluate the Effects of Genotropin in Adult Patients With Growth Hormone Deficiency (GHD) Caused by Trauma and/or Head Injury Terminated NCT00638053 Phase 4
5 High Dose Hyperoncotic Serum Albumin for the Treatment of the Acute Phase of Severe Head Injury Unknown status NCT00152685 Phase 2, Phase 3 human serum albumin
6 School Playground Surfacing - A Randomized Prospective Comparison of Injury Rates on Sand Versus Wood Chip Surfaces Unknown status NCT00213174 Phase 3
7 Evaluation of an Active Strategy to Implement the Canadian CT Head Rule: Phase III Completed NCT00993252 Phase 3
8 Magnesium Sulfate for Neuroprotection After Brain Trauma Completed NCT00004730 Phase 3 magnesium sulfate
9 The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial Completed NCT00878631 Phase 2, Phase 3 hypertonic saline mixed with dextran;Normal Saline
10 The Toronto Prehospital Hypertonic Resuscitation-Head Injury and Multi Organ Dysfunction Trial Completed NCT01642524 Phase 3
11 Multicenter Trial of CPE for Maxillofacial Prosthetics Completed NCT00123097 Phase 3
12 International, Multicenter, Randomized, Single Blind, Placebo-controlled Study of Efficacy and Safety of CITOFLAVIN® in the Acute Period of Head Injury in Adults Active, not recruiting NCT04631484 Phase 3 Cytoflavin ((Inosine + Nicotinamide + Riboflavin + Succinic Acid);Placebo
13 Changes in Morphine Handling and Response in Patients With Brain Trauma Unknown status NCT00196131 Phase 1, Phase 2 morphine
14 Phase 1/2 Multicenter, Randomized, Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury Unknown status NCT00810940 Phase 1, Phase 2 AbelaDrug200;mannitol
15 Hypothermia for Cardiac Arrest in Paediatrics (HypCAP) - Pilot Study Completed NCT00754481 Phase 2
16 Effect of Rosuvastatin on Immunological Markers After Traumatic Brain Injury: Clinical Randomized Double Blind Study Phase 2 Completed NCT00990028 Phase 1, Phase 2 Rosuvastatin;Placebo
17 Phase II Study of Rosuvastatin´s Effect on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Humans With Moderate Head Injury Completed NCT00329758 Phase 2 rosuvastatin;Placebo
18 An Open Label, Proof of Concept Study, to Evaluate the Safety and Biological Effects of Oxycyte™ Perfluorocarbon in Patients With A Severe Head Injury Requiring Intracranial Pressure Monitoring-OX-CL-II-002 Completed NCT00174980 Phase 2 perfluorocarbon emulsion (Oxycyte) infusion
19 Head Injury Treatment With Healthy and Advanced Dietary Supplements (HIT HEADS): A Randomized, Placebo-controlled, Double-blinded, Therapeutic Exploratory Clinical Trial of Branched Chain Amino Acids (BCAA's) in the Treatment of Concussion Recruiting NCT01860404 Phase 2 Branched Chain Amino Acids;Placebo solution
20 The Role of Anxiety Sensitivity in the Maintenance of Chronic Post Concussion Symptoms Terminated NCT00871884 Phase 1, Phase 2
21 Anti-secretory Factor as a Treatment for Adults With Severe Traumatic Head Injury Withdrawn NCT03453749 Phase 2
22 Mobile Phone Text Message Program to Understand Symptoms and Improve Outcomes in Minor Head Injury Patients Completed NCT01668342 Phase 1
23 An Evaluation of Near-Infrared Spectroscopy for Intracranial Hematoma Detection of Head Trauma Patients in the Emergency Department. Unknown status NCT02222597
24 Swallowing Disorders and Consciousness Alteration in Severe Traumatic Brain Injury Patients Unknown status NCT03562104
25 Development of Simulated Hippotherapy System and Investigation of Its Effectiveness in Children With Cerebral Palsy Unknown status NCT03889262
26 Study of Neurobehavioral Outcome in Children or Adolescents With Closed Head Injuries Unknown status NCT00006128
27 Phase I/II Study of Neuroendocrine Dysfunction in Patients With Closed Head Injuries Unknown status NCT00006271
28 Standard Motorcycle Child Safety Helmet Initiative Program for the Safety of Child Pillion Riders in Malaysia Unknown status NCT03619473
29 The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients Unknown status NCT00886054
30 Evaluation of the Serum S100B Protein Assay in the Management of Mild Head Injury Under Anticoagulation Unknown status NCT03345602
31 Computed Tomography Perfusion in Patients With Severe Head Injury Unknown status NCT02756585
32 Development and Validation of a Prognostic Score for Early Death in Head Injury Patients in the Traumatic Brain Injury Intensive Care Unit of Dijon CHU Unknown status NCT02861547
33 Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury Unknown status NCT00006270 cosyntropin;metyrapone
34 Randomized Controlled Trial of Compliant Flooring to Reduce Injuries Due to Falls in Older Adults in a Long-Term Care Facility Unknown status NCT01618786
35 Animated Picture to Improve Provider Adherence to CT Scan for Head Injury Rule Completed NCT01514071
36 The Efficacy of an Aerobic Exercise and Cognitive Training Program on Postconcussive Symptomology Completed NCT03674398
37 Physical Work Capacity After Traumatic Brain Injury Completed NCT00653640
38 Cognitive Behavioral Therapy for Depression After Traumatic Brain Injury Completed NCT00878150
39 Anger Self-Management in Post-Acute Traumatic Brain Injury: Clinical Trial Completed NCT01745146
40 Measuring Vasospasm, Biomarkers, and Neurocognitive Outcomes in Pediatric Traumatic Brain Injury Completed NCT01461902
41 Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions Completed NCT01042899
42 An Online Intervention for Families of Young Children With TBI: I-InTERACT Completed NCT01056146
43 Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Internet-based Interacting Together Everyday, Recovery After Childhood TBI Completed NCT01214694
44 The Effect of Mild Traumatic Brain Injury on Recovery From Injury Completed NCT00295074
45 Improving Mental Health Outcomes of Child Brain Injury Completed NCT00409448
46 A Randomized Controlled Trial Comparing Prescribed Light Exercise to Standard Management for Emergency Department Patients With Acute Mild Traumatic Brain Injury. Completed NCT03084211
47 Effect of Social Marketing on Attitudes Towards Protective Headwear in Older Adults to Reduce Traumatic Brain Injury Completed NCT01582464
48 QuickBrain MRI for Acute Pediatric Head Trauma Completed NCT03291964
49 Non-Missile Penetrating Brain Injuries, Cases Registry in Sohag University Hospital Completed NCT03768778
50 The Impact of Cranioplasty on Local and Global Cerebral Blood Flow as Clinical Outcome Prognostic Factor in Patients Undergoing Decompressive Craniectomy for Severe Head Injury. Completed NCT01113645

Search NIH Clinical Center for Head Injury

Genetic Tests for Head Injury

Anatomical Context for Head Injury

MalaCards organs/tissues related to Head Injury:

40
Brain, Pituitary, Spinal Cord, Eye, Cortex, Temporal Lobe, Heart

Publications for Head Injury

Articles related to Head Injury:

(show top 50) (show all 23007)
# Title Authors PMID Year
1
Contributing Factors Affecting the Severity of Metro Escalator Injuries in the Guangzhou Metro, China. 61 42
33466625 2021
2
Rectal chloral hydrate sedation for computed tomography in young children with head trauma. 42
33655976 2021
3
Functional recovery time after facial fractures: characteristics and associated factors in a sample of patients from southern Brazil. 42
33470368 2021
4
Dog bite Emergency department presentations in Brisbane metro south: Epidemiology and exploratory medical geography for targeted interventions. 61
33364297 2021
5
Cerebral palsy in Canadian Indigenous children. 61
33314061 2021
6
Operative vacuum vaginal delivery: effect of compliance with recommended checklist. 61
31390914 2021
7
The Whole is Greater Than the Sum of its Parts: GCS Versus GCS-Motor for Triage in Geriatric Trauma. 61
33493891 2021
8
Yield of head CT for acute findings in patients presenting to the emergency department. 61
33246274 2021
9
The association between dual-task walking and counting responses and cognitive function and disability after severe head injury: A preliminary study. 61
31989869 2021
10
Different forms of traumatic brain injuries cause different tactile hypersensitivity profiles. 61
33027220 2021
11
The collateral fallout of COVID19 lockdown on patients with head injury from north-west India. 61
33475830 2021
12
Pharmacological blockers of CCR5 and CXCR4 improve recovery after traumatic brain injury. 61
33453212 2021
13
A prospective cross-sectional study examining the documented evaluation of patients at high risk for mild traumatic brain injury. 61
32165070 2021
14
Survival Rates and Biomarkers in a Large Animal Model of Traumatic Brain Injury Combined With Two Different Levels of Blood Loss. 61
32881755 2021
15
Functional recovery after brain injury: Independent predictors of psychosocial outcome one year after TBI. 61
33618172 2021
16
Putting 'CSF-Shift Edema' Hypothesis to Test: Comparing Cisternal and Parenchymal Pressures After Basal Cisternostomy for Head Injury. 61
33412318 2021
17
Association between alcohol intoxication and mortality in severe traumatic brain injury in the emergency department: a retrospective cohort. 61
32941201 2021
18
Radiologic Assessment of Skull Fracture Healing in Young Children. 61
32868623 2021
19
Sport participation and related head injuries following craniosynostosis correction: a survey study. 61
33794495 2021
20
Tau Imaging in Head Injury. 61
33648666 2021
21
Review article: Developing the Australian and New Zealand Guideline for Mild to Moderate Head Injuries in Children: An adoption/adaption approach. 61
33528917 2021
22
Australian and New Zealand Guideline for Mild to Moderate Head Injuries in Children. 61
33528896 2021
23
Conservative treatment and outcome of upper cervical spine fractures in young children: A STROBE-compliant case series. 61
33787631 2021
24
A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial. 61
33678038 2021
25
Vestibular and Ocular/Oculomotor Assessment Strategies and Outcomes Following Sports-Related Concussion: A Scoping Review. 61
33400218 2021
26
Management of anteromedial coronoid fractures according to a protocol focused on instability assessment provides good outcomes with infrequent need for coronoid fixation. 61
32791098 2021
27
An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain. 61
33037509 2021
28
Factors associated with recurrent transient global amnesia: systematic review and pathophysiological insights. 61
33675214 2021
29
Bilateral irreducible asymmetrical fracture-dislocation of the hip: A case report and literature review. 61
33774447 2021
30
The Original Cushing Society: A Historical Review of the Senior Society's First 6 Meetings. 61
33307257 2021
31
Repeat CT after blunt head trauma and Glasgow Coma Scale score 13-15 without neurological deterioration is very low yield for intervention. 61
33755772 2021
32
Interpersonal violence and head injury: The effects on treatment for PTSD. 61
33271049 2021
33
Blunt Traumatic Aortic Injury: 10-Year Single-Center Experience. 61
33761566 2021
34
The Association of Ketamine Induction with Blood Pressure changes in Paramedic Rapid Sequence Intubation of Out-Of-Hospital Traumatic Brain Injury. 61
33759253 2021
35
Ranking and Rating Bicycle Helmet Safety Performance in Oblique Impacts Using Eight Different Brain Injury Models. 61
33475893 2021
36
Poor Parental Supervision Associated With Traumatic Brain Injury and Reactive Aggression in Young Offenders. 61
33782348 2021
37
Proton extrusion during oxidative burst in microglia exacerbates pathological acidosis following traumatic brain injury. 61
33090575 2021
38
Performance on the repeatable battery for the assessment of neuropsychological status in college students with mild traumatic brain injury. 61
31230481 2021
39
An Exploratory Report on Electrographic Changes in the Cerebral Cortex Following Mild Traumatic Brain Injury with Hyperthermia in the Rat. 61
32366168 2021
40
Unique diagnostic signatures of concussion in the saliva of male athletes: the Study of Concussion in Rugby Union through MicroRNAs (SCRUM). 61
33757972 2021
41
Impact of the Lockdown due to COVID-19 Pandemic on the Spectrum and Outcome of Trauma in India. 61
33790506 2021
42
Fiber optic sensor embedded smart helmet for real-time impact sensing and analysis through machine learning. 61
33440230 2021
43
[Fatty Density and Air]. 61
33762448 2021
44
The Role of Obesity in Motor Vehicle Injuries and Fatalities in the Pediatric Population: A Systematic Review. 61
33685267 2021
45
Does health service utilisation mediate the effect of disability on psychological distress: Evidence from a national representative survey in Australia. 61
32878539 2021
46
Prognostic value of CT perfusion and permeability imaging in traumatic brain injury. 61
33009337 2021
47
Nephrectomy is Associated with Increased Mortality after Renal Trauma: An Analysis of the National Trauma Data Bank from 2007-2016. 61
33021435 2021
48
Classification of Comprehensive Neuro-Ophthalmologic Measures of Postacute Concussion. 61
33656530 2021
49
Return to learn: An ethnographic study of adolescent young adults returning to school post-concussion. 61
33351994 2021
50
Utility of non-contrast head computed tomography in poisoned patients. 61
33713541 2021

Variations for Head Injury

Expression for Head Injury

Search GEO for disease gene expression data for Head Injury.

Pathways for Head Injury

GO Terms for Head Injury

Biological processes related to Head Injury according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 thymus development GO:0048538 9.54 SOD1 BCL2
2 negative regulation of endothelial cell proliferation GO:0001937 9.52 PRL APOE
3 ovarian follicle development GO:0001541 9.51 SOD1 BCL2
4 reactive oxygen species metabolic process GO:0072593 9.49 SOD1 BCL2
5 positive regulation of catalytic activity GO:0043085 9.48 SOD1 BCL2
6 regulation of mitochondrial membrane potential GO:0051881 9.46 SOD1 BCL2
7 T cell homeostasis GO:0043029 9.43 IL2RA BCL2
8 negative regulation of neuron apoptotic process GO:0043524 9.43 SOD1 BCL2 APOE
9 cell aging GO:0007569 9.4 SOD1 BCL2
10 regulation of multicellular organism growth GO:0040014 9.37 SOD1 PRL
11 negative regulation of inflammatory response GO:0050728 9.33 SOD1 IL2RA APOE
12 response to reactive oxygen species GO:0000302 9.32 SOD1 APOE
13 response to oxidative stress GO:0006979 9.13 SOD1 BCL2 APOE
14 negative regulation of cholesterol biosynthetic process GO:0045541 8.62 SOD1 APOE

Molecular functions related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tau protein binding GO:0048156 8.96 S100B APOE
2 antioxidant activity GO:0016209 8.62 SOD1 APOE

Sources for Head Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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