MCID: HRT003
MIFTS: 25

Heart Lymphoma

Categories: Blood diseases, Cancer diseases, Cardiovascular diseases, Immune diseases

Aliases & Classifications for Heart Lymphoma

MalaCards integrated aliases for Heart Lymphoma:

Name: Heart Lymphoma 12 15
Lymphoma of Heart 12
Cardiac Lymphoma 70

Classifications:



External Ids:

Disease Ontology 12 DOID:6547
NCIt 50 C5368
UMLS 70 C1332850

Summaries for Heart Lymphoma

MalaCards based summary : Heart Lymphoma, also known as lymphoma of heart, is related to b-cell lymphoma and bladder lymphoma. An important gene associated with Heart Lymphoma is BCL6 (BCL6 Transcription Repressor), and among its related pathways/superpathways are T cell receptor signaling pathway and Primary Focal Segmental Glomerulosclerosis FSGS. Affiliated tissues include heart, breast and lung, and related phenotypes are integument and normal

Related Diseases for Heart Lymphoma

Diseases related to Heart Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 163)
# Related Disease Score Top Affiliating Genes
1 b-cell lymphoma 28.9 PTPRC MME BCL6 ALK
2 bladder lymphoma 10.2 MME BCL6
3 ureteral lymphoma 10.2 MME BCL6
4 chest wall lymphoma 10.2 MME BCL6
5 paranasal sinus lymphoma 10.2 MME BCL6
6 prostate lymphoma 10.2 MME BCL6
7 ovarian lymphoma 10.2 MME BCL6
8 lung lymphoma 10.2 MME BCL6
9 colon lymphoma 10.2 MME BCL6
10 appendix lymphoma 10.2 MME BCL6
11 intravascular large b-cell lymphoma 10.2 MME BCL6
12 gray zone lymphoma 10.2 MME BCL6
13 nasal cavity lymphoma 10.2 MME BCL6
14 gastrointestinal lymphoma 10.2 MME BCL6
15 tracheal lymphoma 10.2 MME BCL6
16 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.2 PTPRC BCL6
17 composite lymphoma 10.2 MME BCL6
18 testicular lymphoma 10.2 MME BCL6
19 plasmablastic lymphoma 10.2 PTPRC BCL6
20 lymphosarcoma 10.2 PTPRC BCL6
21 spleen cancer 10.2 MME BCL6
22 nodal marginal zone lymphoma 10.2 MME BCL6
23 cll/sll 10.2 MME BCL6
24 central nervous system hematologic cancer 10.2 MME BCL6
25 lymphoplasmacytic lymphoma 10.2 MME BCL6
26 epididymis adenocarcinoma 10.2 PTPRC MME
27 lung combined type small cell carcinoma 10.2 MYOG MME
28 epididymis cancer 10.2 PTPRC MME
29 epididymal neoplasm 10.1 MME CD68
30 cervical polyp 10.1 MYOG MME
31 sarcomatoid squamous cell skin carcinoma 10.1 MME CD68
32 balloon cell malignant melanoma 10.1 MME CD68
33 pulmonary artery leiomyosarcoma 10.1 MME CD68
34 breast sarcoma 10.1 MYOG MME
35 cobblestone retinal degeneration 10.1 PTPRC CD68
36 cervical adenosarcoma 10.1 MYOG MME
37 small intestinal sarcoma 10.1 PTPRC CD68
38 fallopian tube endometrioid adenocarcinoma 10.1 MYOG MME
39 kidney cortex disease 10.1 MYOG MME
40 villonodular synovitis 10.1 PTPRC CD68
41 glomeruloid hemangioma 10.1 PTPRC CD68
42 histiocytic and dendritic cell cancer 10.1 PTPRC CD68
43 malignant giant cell tumor of soft parts 10.1 PTPRC CD68
44 angioimmunoblastic t-cell lymphoma 10.1 MME BCL6
45 olfactory nerve neoplasm 10.1 PTPRC MYOG
46 conventional fibrosarcoma 10.1 PTPRC CD68
47 cranial nerve malignant neoplasm 10.1 PTPRC MYOG
48 marginal zone b-cell lymphoma 10.1 MME BCL6
49 pleomorphic rhabdomyosarcoma 10.1 MYOG MME
50 vaginal endometrial stromal sarcoma 10.1 VIM MME

Graphical network of the top 20 diseases related to Heart Lymphoma:



Diseases related to Heart Lymphoma

Symptoms & Phenotypes for Heart Lymphoma

MGI Mouse Phenotypes related to Heart Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.55 ALK BCL6 MME MYOG PTPRC
2 normal MP:0002873 9.35 ALK BCL6 MYOG PTPRC VIM
3 respiratory system MP:0005388 9.02 ALK BCL6 MYOG PTPRC VIM

Drugs & Therapeutics for Heart Lymphoma

Search Clinical Trials , NIH Clinical Center for Heart Lymphoma

Genetic Tests for Heart Lymphoma

Anatomical Context for Heart Lymphoma

MalaCards organs/tissues related to Heart Lymphoma:

40
Heart, Breast, Lung, Skin, Myeloid, Bone, Spleen

Publications for Heart Lymphoma

Articles related to Heart Lymphoma:

# Title Authors PMID Year
1
A presentation, treatment, and survival analysis of primary cardiac lymphoma cases reported from 2009 to 2019. 61
32285360 2020
2
Cardiac pacing for complete atrioventricular block complicating heart lymphoma: A challenging issue. 61
29933920 2018
3
[Diagnosis and results of treatment of heart myxoma]. 61
22165750 2011
4
Diffuse large B-cell lymphoma of non-germinal center B-cell type of the heart in an immunocompetent woman: an autopsy case. 61
20066521 2011
5
Heart lymphoma 6 years after a prosthetic ascending aorta replacement: related or unrelated? 61
17287694 2007
6
[Heart rupture at the right atrial level as the first manifestation of malignant lymphoma]. 61
8697472 1996
7
Primary non-hodgkins lymphoma of heart in AIDS. 61
18750230 1987

Variations for Heart Lymphoma

Expression for Heart Lymphoma

Search GEO for disease gene expression data for Heart Lymphoma.

Pathways for Heart Lymphoma

GO Terms for Heart Lymphoma

Cellular components related to Heart Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 focal adhesion GO:0005925 8.8 VIM PTPRC MME

Biological processes related to Heart Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of B cell proliferation GO:0030890 8.62 PTPRC BCL6

Molecular functions related to Heart Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin DNA binding GO:0031490 8.62 MYOG BCL6

Sources for Heart Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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