MCID: HRT017
MIFTS: 20

Heart Tumor

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Heart Tumor

MalaCards integrated aliases for Heart Tumor:

Name: Heart Tumor 53 55
Primary Cardiac Tumors, Childhood 53
Intracavitary Tumors of the Heart 73
Neoplasm of Myocardium 73
Intracavitary Tumors 53
Myocardial Tumors 53
Heart Neoplasm 73

Classifications:



External Ids:

Summaries for Heart Tumor

MalaCards based summary : Heart Tumor, also known as primary cardiac tumors, childhood, is related to primary pediatric heart tumor and primary adult heart tumor. An important gene associated with Heart Tumor is CCL26 (C-C Motif Chemokine Ligand 26). The drugs Trioxsalen and Dermatologic Agents have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Heart Tumor

Diseases in the Heart Tumor family:

Primary Adult Heart Tumor

Diseases related to Heart Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 primary pediatric heart tumor 12.0
2 primary adult heart tumor 12.0
3 myocardium cancer 11.1
4 seminoma 9.8
5 testicular seminoma 9.8
6 dilated cardiomyopathy 9.8
7 cardiac arrhythmia 9.5
8 pierre robin syndrome 9.5
9 cardiac arrest 9.5
10 fibrosarcoma 9.5
11 syncope 9.5

Graphical network of the top 20 diseases related to Heart Tumor:



Diseases related to Heart Tumor

Symptoms & Phenotypes for Heart Tumor

GenomeRNAi Phenotypes related to Heart Tumor according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.8 PTCH1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.8 CCL26
3 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.8 CCL26
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.8 CCL26
5 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.8 CCL26
6 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.8 CCL26
7 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.8 CCL26
8 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.8 PTCH1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.8 PTCH1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.8 CCL26 PTCH1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.8 CCL26
12 Increased shRNA abundance (Z-score > 2) GR00366-A-79 9.8 CCL26 PTCH1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.8 CCL26

Drugs & Therapeutics for Heart Tumor

Drugs for Heart Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trioxsalen Approved Phase 3 3902-71-4 5585
2 Dermatologic Agents Phase 3
3 Photosensitizing Agents Phase 3
4 Hematoporphyrin Derivative Phase 3
5 Ether Phase 3
6 Dihematoporphyrin Ether Phase 3
7 Hematoporphyrins Phase 3
8
Racepinephrine Approved 329-65-7 838
9
Epinephrine Approved, Vet_approved 51-43-4 5816
10
N,N-dimethylarginine Experimental Not Applicable 30315-93-6 123831
11 Natriuretic Peptide, Brain Not Applicable
12 Natriuretic Agents Not Applicable
13 Epinephryl borate

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer Recruiting NCT02628665 Phase 3 photosensitizer(photofrin)
2 Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors Completed NCT01560260 Phase 2 Linsitinib
3 Transplantation of Human Embryonic Stem Cell-derived Progenitors in Severe Heart Failure Completed NCT02057900 Phase 1
4 Japanese OMI Treatment With Kit-positive Cells for Enhanced Regeneration Recruiting NCT03351400 Phase 1
5 Cardiac Tumors Interventional (Radio Frequency/Laser Ablation)Therapy Unknown status NCT02815553 Not Applicable
6 Multidetector Raw CT as a Single Tool in the Setting of Ischemic Stroke Completed NCT00708188 Not Applicable
7 Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis Completed NCT03377465 Not Applicable
8 Medical Record Study on Adverse Events Requiring a Higher Level of Care in Flemish Hospitals Completed NCT02044718
9 Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the CARNEY Complex (CNC) Completed NCT00668291
10 Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients Recruiting NCT03444259
11 Familial Investigations of Childhood Cancer Predisposition Recruiting NCT03050268
12 Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex Recruiting NCT00001452
13 Cancer Development In Organ Transplant Recipients Active, not recruiting NCT02333279
14 Cardiac Tumors in Children Terminated NCT00215085

Search NIH Clinical Center for Heart Tumor

Genetic Tests for Heart Tumor

Anatomical Context for Heart Tumor

MalaCards organs/tissues related to Heart Tumor:

41
Heart

Publications for Heart Tumor

Articles related to Heart Tumor:

# Title Authors Year
1
A Giant Heart Tumor in Neonate with Clinical Signs of Pierre - Robin Syndrome. ( 28790548 )
2017
2
Heart palpitations as anA early presentation of aA heart tumor. ( 28009999 )
2016
3
ECG of the Month. Cardiac arrhythmia associated with atrial fibrosis and a heart tumor. ( 23902440 )
2013
4
Case report of death from falling: Did heart tumor cause syncope? ( 22081041 )
2012
5
Implantable cardioverter defibrillator in a 4-month-old infant with cardiac arrest associated with a vascular heart tumor. ( 11816644 )
2001
6
An uncommon heart tumor: the fibrosarcoma. ( 9251742 )
1997
7
Prenatal diagnosis of a heart tumor. ( 3400578 )
1988
8
Resection of a heart tumor using autotransplantation. ( 3287682 )
1988
9
Electrocardiographic diagnosis of a metastatic heart tumor. ( 1277832 )
1976
10
Primary malignant heart tumor diagnosed in vivo with the aid of artificial pneumopericardium. ( 18107158 )
1949

Variations for Heart Tumor

Expression for Heart Tumor

Search GEO for disease gene expression data for Heart Tumor.

Pathways for Heart Tumor

GO Terms for Heart Tumor

Sources for Heart Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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