MCID: HVY003
MIFTS: 19

Heavy Chain Deposition Disease

Categories: Blood diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Heavy Chain Deposition Disease

Summaries for Heavy Chain Deposition Disease

MalaCards based summary : Heavy Chain Deposition Disease, also known as hcdd, is related to light and heavy chain deposition disease and gamma heavy chain disease. An important gene associated with Heavy Chain Deposition Disease is IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)). Affiliated tissues include lung, bone and skin.

Related Diseases for Heavy Chain Deposition Disease

Graphical network of the top 20 diseases related to Heavy Chain Deposition Disease:



Diseases related to Heavy Chain Deposition Disease

Symptoms & Phenotypes for Heavy Chain Deposition Disease

Drugs & Therapeutics for Heavy Chain Deposition Disease

Search Clinical Trials , NIH Clinical Center for Heavy Chain Deposition Disease

Genetic Tests for Heavy Chain Deposition Disease

Anatomical Context for Heavy Chain Deposition Disease

MalaCards organs/tissues related to Heavy Chain Deposition Disease:

42
Lung, Bone, Skin, Kidney, Skeletal Muscle, Bone Marrow, B Cells

Publications for Heavy Chain Deposition Disease

Articles related to Heavy Chain Deposition Disease:

(show top 50) (show all 57)
# Title Authors Year
1
α1-Heavy Chain Deposition Disease With Negative Immunofluorescence Staining on Renal Biopsy. ( 30596184 )
2019
2
Monoclonal Gammopathy of Renal Significance with Heavy Chain Deposition Disease in Renal allograft: Challenges in the diagnosis and management. ( 31081947 )
2019
3
Acquired Cutis Laxa Associated with Light and Heavy Chain Deposition Disease. ( 29441298 )
2018
4
Cutis laxa for diagnosis of γ1-heavy-chain deposition disease: Report of four cases. ( 30035313 )
2018
5
IgA kappa light and heavy chain deposition disease in multiple myeloma. ( 29808912 )
2018
6
Comprehensive molecular characterization of a heavy chain deposition disease case. ( 30026336 )
2018
7
Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management. ( 27773425 )
2017
8
New insights into the pathogenesis and treatment of heavy chain deposition disease. ( 28087006 )
2017
9
Long-term renal survival of γ3-heavy chain deposition disease: a case report. ( 28716013 )
2017
10
AJKD Atlas of Renal Pathology: Light and Heavy Chain Deposition Disease. ( 26802334 )
2016
11
AJKD Atlas of Renal Pathology: Heavy Chain Deposition Disease. ( 26916378 )
2016
12
IgD heavy-chain deposition disease: detection by laser microdissection and mass spectrometry. ( 25194005 )
2015
13
Light and heavy chain deposition disease associated with CH1 deletion. ( 25815184 )
2015
14
A Case of IgG2 Heavy Chain Deposition Disease in a Patient with Kappa Positive Plasma Cell Dyscrasia. ( 25849668 )
2015
15
A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy. ( 26113545 )
2015
16
Acquired cutis laxa associated with heavy chain deposition disease involving dermal elastic fibers. ( 25133950 )
2014
17
A case of renal γ2 heavy-chain deposition disease accompanied by rapid progressive renal failure. ( 23963539 )
2014
18
Use of bortezomib in heavy-chain deposition disease: a report of 3 cases. ( 24613055 )
2014
19
A unique case of γ-heavy chain deposition disease characterized by concomitant deposition of γ2 and γ4 subclasses. ( 25400185 )
2014
20
Probable light- and heavy-chain deposition disease in a patient with nodular diabetic glomerulosclerosis. ( 28509191 )
2014
21
Gamma 1-heavy chain deposition disease accompanied by IgG kappa in serum, urine, and bone marrow. ( 28509245 )
2014
22
Heavy chain deposition disease: an overview. ( 23652830 )
2013
23
High-dose melphalan followed by auto-SCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease. ( 21499318 )
2012
24
Long-term follow-up after autologous stem cell transplantation for light- and heavy-chain deposition disease. ( 22231462 )
2012
25
Heavy-chain deposition disease: a morphological, immunofluorescence and ultrastructural assessment. ( 26019812 )
2012
26
Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature. ( 21944962 )
2011
27
Intracellular extraocular muscle light- and heavy-chain deposition disease contributing to compressive optic neuropathy in a patient with preexisting Graves' orbitopathy. ( 19707026 )
2010
28
Pulmonary light and heavy chain deposition disease: a pitfall for lung cancer evaluation with F-18 FDG PET/CT. ( 20631525 )
2010
29
A case of γ1-heavy chain deposition disease successfully treated with melphalan and prednisolone therapy. ( 20647658 )
2010
30
Clinicopathological features and prognosis in immunoglobulin light and heavy chain deposition disease. ( 19203545 )
2009
31
Acquired cutis laxa associated with heavy chain deposition disease. ( 19119136 )
2008
32
Clinical remission and histopathological resolution of nodular lesions in a patient with gamma3 heavy-chain deposition disease. ( 18538103 )
2008
33
A concurrence of light and heavy chain deposition disease and diabetic nephropathy. ( 18041443 )
2007
34
Immunoglobulin light (heavy)-chain deposition disease: from molecular medicine to pathophysiology-driven therapy. ( 17699367 )
2006
35
Development of systemic lambda-light chain amyloidosis in a patient with gamma-heavy chain deposition disease during long-term follow-up. ( 15673693 )
2005
36
Recurrent light and heavy chain deposition disease after renal transplantation. ( 15840680 )
2005
37
A case of monoclonal immunoglobulin light- and heavy-chain deposition disease exhibiting atypical deposition with fibrillary structures, successfully treated with chemotherapy. ( 16175947 )
2005
38
Light- and heavy-chain deposition disease (LHCDD): difficulty in diagnosis and treatment. ( 16258202 )
2005
39
High dose chemotherapy and stem cell support in a patient of light- and heavy-chain deposition disease with abnormal marrow cell surface antigens and no monoclonal protein. ( 16258214 )
2005
40
Immunoglobulin gamma3-heavy-chain deposition disease: report of a case and relationship with hypocomplementemia. ( 14712467 )
2004
41
High dose chemotherapy in light chain or light and heavy chain deposition disease. ( 14717936 )
2004
42
Intracapillary proliferative glomerulonephritis due to heavy chain deposition disease. ( 15102968 )
2004
43
Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease. ( 15172359 )
2004
44
Generalized cutis laxa associated with heavy chain deposition disease. ( 14973644 )
2003
45
Articular, monoclonal gamma3 heavy-chain deposition disease: characterization of a partially deleted heavy-chain gene and its protein product synthesized in vivo and in vitro. ( 14613292 )
2003
46
Abnormal immunoglobulin synthesis in monoclonal immunoglobulin light chain and light and heavy chain deposition disease. ( 11409038 )
2001
47
Heavy chain deposition disease: recurrence in a renal transplant and report of IgG(2) subtype. ( 10793054 )
2000
48
The amino acid sequence of a monoclonal gamma 3-heavy chain from a patient with articular gamma-heavy chain deposition disease. ( 10849371 )
2000
49
Heavy chain deposition disease: the disease spectrum. ( 10213655 )
1999
50
Non-amyloid fibrils in heavy chain deposition disease. ( 10504516 )
1999

Variations for Heavy Chain Deposition Disease

Expression for Heavy Chain Deposition Disease

Search GEO for disease gene expression data for Heavy Chain Deposition Disease.

Pathways for Heavy Chain Deposition Disease

GO Terms for Heavy Chain Deposition Disease

Sources for Heavy Chain Deposition Disease

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75 UMLS via Orphanet
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