HCDD
MCID: HVY003
MIFTS: 18

Heavy Chain Deposition Disease (HCDD)

Categories: Blood diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Heavy Chain Deposition Disease

MalaCards integrated aliases for Heavy Chain Deposition Disease:

Name: Heavy Chain Deposition Disease 58 70
Hcdd 58

Classifications:

Orphanet: 58  
Rare renal diseases
Rare haematological diseases


External Ids:

ICD10 via Orphanet 33 D89.8
Orphanet 58 ORPHA93556
UMLS 70 C1333947

Summaries for Heavy Chain Deposition Disease

MalaCards based summary : Heavy Chain Deposition Disease, also known as hcdd, is related to light and heavy chain deposition disease and gamma heavy chain disease. An important gene associated with Heavy Chain Deposition Disease is IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)). Affiliated tissues include kidney, bone marrow and skeletal muscle.

Related Diseases for Heavy Chain Deposition Disease

Graphical network of the top 20 diseases related to Heavy Chain Deposition Disease:



Diseases related to Heavy Chain Deposition Disease

Symptoms & Phenotypes for Heavy Chain Deposition Disease

Drugs & Therapeutics for Heavy Chain Deposition Disease

Search Clinical Trials , NIH Clinical Center for Heavy Chain Deposition Disease

Genetic Tests for Heavy Chain Deposition Disease

Anatomical Context for Heavy Chain Deposition Disease

MalaCards organs/tissues related to Heavy Chain Deposition Disease:

40
Kidney, Bone Marrow, Skeletal Muscle

Publications for Heavy Chain Deposition Disease

Articles related to Heavy Chain Deposition Disease:

(show top 50) (show all 126)
# Title Authors PMID Year
1
First case report of monoclonal IgG3-heavy-chain glomerulonephritis with microtubular structures. 61
33156494 2021
2
The First Step of Biodegradation of 7-Hydroxycoumarin in Pseudomonas mandelii 7HK4 Depends on an Alcohol Dehydrogenase-Type Enzyme. 61
33557119 2021
3
Heavy Lifting: Nomenclature and Novel Therapy for Gamma Heavy Chain Disease and Other Heavy Chain Disorders. 61
32245744 2020
4
Heavy Chain Deposition Disease: Clinicopathologic Characteristics of a Chinese Case Series. 61
31699519 2020
5
Heavy chain deposition disease presenting with raised anti-GBM antibody levels; a case report. 61
32398029 2020
6
Heavy Chain Fibrillary Glomerulonephritis: A Case Report. 61
30955945 2019
7
Monoclonal gammopathy of renal significance with heavy-chain deposition disease in renal allograft: challenges in the diagnosis and management. 61
31081947 2019
8
Randall-type monoclonal immunoglobulin deposition disease: novel insights from a nationwide cohort study. 61
30578255 2019
9
α1-Heavy Chain Deposition Disease With Negative Immunofluorescence Staining on Renal Biopsy. 61
30596184 2019
10
Comprehensive molecular characterization of a heavy chain deposition disease case. 61
30026336 2018
11
Cutis laxa for diagnosis of γ1-heavy-chain deposition disease: Report of four cases. 61
30035313 2018
12
IgA kappa light and heavy chain deposition disease in multiple myeloma. 61
29808912 2018
13
Acquired Cutis Laxa Associated with Light and Heavy Chain Deposition Disease. 61
29441298 2018
14
Long-term renal survival of γ3-heavy chain deposition disease: a case report. 61
28716013 2017
15
The clinicopathologic characteristics of kidney diseases related to monotypic IgA deposits. 61
28069266 2017
16
Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management. 61
27773425 2017
17
New insights into the pathogenesis and treatment of heavy chain deposition disease. 61
28087006 2017
18
"Diabetic nephropathy" in a non-diabetic patient. 61
27688084 2016
19
Kidney disease in the elderly: biopsy based data from 14 renal centers in Poland. 61
27884116 2016
20
[Randall-type monoclonal immunoglobulin deposition disease: From diagnosis to treatment]. 61
27117766 2016
21
AJKD Atlas of Renal Pathology: Heavy Chain Deposition Disease. 61
26916378 2016
22
AJKD Atlas of Renal Pathology: Light and Heavy Chain Deposition Disease. 61
26802334 2016
23
[A case of light and heavy chain deposition disease]. 61
26819434 2016
24
Combined IgG4κ and IgG1λ deposition in the glomerular and tubular basement membrane accompanied by autoimmune neutropenia (AIN) and immune thrombocytopenia (ITP). 61
28509103 2015
25
Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy. 61
26125609 2015
26
A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy. 61
26113545 2015
27
Light and heavy chain deposition disease associated with CH1 deletion. 61
25815184 2015
28
IgD heavy-chain deposition disease: detection by laser microdissection and mass spectrometry. 61
25194005 2015
29
A Case of IgG2 Heavy Chain Deposition Disease in a Patient with Kappa Positive Plasma Cell Dyscrasia. 61
25849668 2015
30
Clinical significance of dynamic monitoring by transcranial doppler ultrasound and intracranial pressure monitor after surgery of hypertensive intracerebral hemorrhage. 61
26379963 2015
31
Acquired cutis laxa associated with heavy chain deposition disease involving dermal elastic fibers. 61
25133950 2014
32
Probable light- and heavy-chain deposition disease in a patient with nodular diabetic glomerulosclerosis. 61
28509191 2014
33
Use of bortezomib in heavy-chain deposition disease: a report of 3 cases. 61
24613055 2014
34
A case of renal γ2 heavy-chain deposition disease accompanied by rapid progressive renal failure. 61
23963539 2014
35
Gamma 1-heavy chain deposition disease accompanied by IgG kappa in serum, urine, and bone marrow. 61
28509245 2014
36
A unique case of γ-heavy chain deposition disease characterized by concomitant deposition of γ2 and γ4 subclasses. 61
25400185 2014
37
Hypertension, renal failure, and edema in a 38-year-old man: light chain deposition disease; a case report and review of the literature. 61
24772399 2014
38
Heavy chain deposition disease: an overview. 61
23652830 2013
39
Relapsing proliferative glomerulonephritis with monoclonal IgG deposits showing circumferential crescentic glomerulonephritis. 61
26069833 2013
40
An unusual cause of gross hematuria and renal dysfunction in a young male. 61
24049277 2013
41
Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system. 61
22592598 2013
42
Proliferative glomerulonephritis with discrete deposition of monoclonal immunoglobulin γ1 CH 2 heavy chain and κ light chain: a new variant of monoclonal immunoglobulin deposition disease. 61
23356227 2013
43
Craniovertebral junction pathology in high cervical disc disease. 61
22698391 2012
44
Heavy-chain deposition disease: a morphological, immunofluorescence and ultrastructural assessment. 61
26019812 2012
45
Long-term follow-up after autologous stem cell transplantation for light- and heavy-chain deposition disease. 61
22231462 2012
46
High-dose melphalan followed by auto-SCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease. 61
21499318 2012
47
Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institution. 61
22156754 2012
48
Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature. 61
21944962 2011
49
Generalized acquired cutis laxa associated with multiple myeloma with biphenotypic IgG-λ and IgA-κ gammopathy following treatment of a nodal plasmacytoma. 61
21422340 2011
50
Monoclonal immunoglobulin light and heavy chain deposition diseases: molecular models of common renal diseases. 61
21252522 2011

Variations for Heavy Chain Deposition Disease

Expression for Heavy Chain Deposition Disease

Search GEO for disease gene expression data for Heavy Chain Deposition Disease.

Pathways for Heavy Chain Deposition Disease

GO Terms for Heavy Chain Deposition Disease

Sources for Heavy Chain Deposition Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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