MCID: HMN036
MIFTS: 53

Hemangiopericytoma, Malignant

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Hemangiopericytoma, Malignant

MalaCards integrated aliases for Hemangiopericytoma, Malignant:

Name: Hemangiopericytoma, Malignant 57 12 73
Hemangiopericytoma 12 76 53 55 44 15 73
Solitary Fibrous Tumor 59 73
Haemangiopericytic Meningioma 12
Malignant Hemangiopericytoma 12

Characteristics:

Orphanet epidemiological data:

59
solitary fibrous tumor
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

OMIM:

57
Inheritance:
autosomal recessive


HPO:

32
hemangiopericytoma, malignant:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 57 234820
Disease Ontology 12 DOID:264
MeSH 44 D006393
NCIt 50 C3087
SNOMED-CT 68 134335004 36060005
Orphanet 59 ORPHA2126
UMLS via Orphanet 74 C1266119 C0018922
MESH via Orphanet 45 D006393
ICD10 via Orphanet 34 D21.9
MedGen 42 C0334542
SNOMED-CT via HPO 69 258211005 49601007

Summaries for Hemangiopericytoma, Malignant

NIH Rare Diseases : 53 Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules. These types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body.

MalaCards based summary : Hemangiopericytoma, Malignant, also known as hemangiopericytoma, is related to meninges hemangiopericytoma and hypoglycemic coma. An important gene associated with Hemangiopericytoma, Malignant is STAT6 (Signal Transducer And Activator Of Transcription 6), and among its related pathways/superpathways are ERK Signaling and Cytoskeletal Signaling. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and thyroid, and related phenotypes are abnormality of the cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.

Wikipedia : 76 A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the... more...

Description from OMIM: 234820

Related Diseases for Hemangiopericytoma, Malignant

Diseases in the Hemangiopericytoma, Malignant family:

Adult Malignant Hemangiopericytoma

Diseases related to Hemangiopericytoma, Malignant via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 221)
# Related Disease Score Top Affiliating Genes
1 meninges hemangiopericytoma 31.0 IGF2 STAT6 VIM
2 hypoglycemic coma 30.8 HBA1 IGF2
3 liposarcoma 30.5 DES MDM2 VIM
4 pseudosarcomatous fibromatosis 30.3 ACTC1 DES VIM
5 desmoplastic small round cell tumor 30.3 DES MUC1 VIM
6 neurofibroma 30.0 F13A1 MUC1 S100B
7 spindle cell lipoma 30.0 ACTC1 DES MDM2 VIM
8 myoepithelioma 30.0 ACTC1 S100B VIM
9 dedifferentiated liposarcoma 29.9 ACTC1 DES MDM2 MUC1
10 leiomyoma 29.9 ACTC1 DES IGF2 VIM
11 sarcoma, synovial 29.8 DES MDM2 MUC1 VIM
12 fibrous meningioma 29.8 F13A1 MUC1 S100B VIM
13 fasciitis 29.8 ACTC1 DES MUC1 VIM
14 chordoma 29.5 DES MUC1 S100B VIM
15 gastrointestinal stromal tumor 29.3 ACTC1 DES IGF2 S100B VIM
16 rhabdomyosarcoma 29.2 ACTC1 DES IGF2 MDM2 VIM
17 pleomorphic adenoma 29.0 ACTC1 MDM2 MUC1 S100B VIM
18 fibrous histiocytoma 28.9 ACTC1 DES F13A1 S100B VIM
19 dermatofibrosarcoma protuberans 28.9 ACTC1 DES F13A1 S100B VIM
20 malignant peripheral nerve sheath tumor 28.8 ACTC1 MDM2 MUC1 S100B VIM
21 malignant pleural solitary fibrous tumor 12.3
22 malignant peritoneal solitary fibrous tumor 12.2
23 desmoid tumor 11.4
24 benign fibrous mesothelioma 11.4
25 liver fibroma 11.2
26 heart malignant hemangiopericytoma 11.0
27 malignant mediastinum hemangiopericytoma 11.0
28 adult intracranial malignant hemangiopericytoma 11.0
29 childhood malignant hemangiopericytoma 11.0
30 infantile digital fibromatosis 10.8 DES VIM
31 lymphangiomatosis 10.8 DES VIM
32 lymphangiectasis 10.8 ACTC1 VIM
33 primitive neuroectodermal tumor of the cervix uteri 10.8 DES VIM
34 glomangiomyoma 10.8 ACTC1 VIM
35 intravascular papillary endothelial hyperplasia 10.8 ACTC1 VIM
36 ovarian fibrothecoma 10.8 ACTC1 DES
37 botryoid rhabdomyosarcoma 10.7 ACTC1 DES
38 malignant peritoneal mesothelioma 10.7 MUC1 VIM
39 papillary tumor of the pineal region 10.7 MUC1 VIM
40 spindle cell thymoma 10.7 DES MUC1
41 progressive nodular histiocytosis 10.7 ACTC1 F13A1
42 multicentric reticulohistiocytosis 10.7 F13A1 VIM
43 malignant mixed mullerian tumor 10.7 MUC1 VIM
44 scleromyxedema 10.7 ACTC1 F13A1
45 nodular hidradenoma 10.7 MUC1 VIM
46 endometrial mucinous adenocarcinoma 10.7 MUC1 VIM
47 granuloma annulare 10.7 F13A1 VIM
48 sclerosing liposarcoma 10.6 MDM2 STAT6
49 pulmonary vein stenosis 10.6 ACTC1 DES
50 retroperitoneal fibrosis 10.6 MDM2 VIM

Graphical network of the top 20 diseases related to Hemangiopericytoma, Malignant:



Diseases related to Hemangiopericytoma, Malignant

Symptoms & Phenotypes for Hemangiopericytoma, Malignant

Symptoms via clinical synopsis from OMIM:

57
Vascular:
malignant hemangiopericytoma


Clinical features from OMIM:

234820

Human phenotypes related to Hemangiopericytoma, Malignant:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the cardiovascular system 32 HP:0001626

MGI Mouse Phenotypes related to Hemangiopericytoma, Malignant:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.11 ACTC1 DES F13A1 FGF23 IGF2 MDM2
2 cardiovascular system MP:0005385 10.06 ACTC1 DES F13A1 FGF23 HACL1 IGF2
3 mortality/aging MP:0010768 9.96 ACTC1 DES F13A1 FGF23 IGF2 MDM2
4 integument MP:0010771 9.87 FGF23 IGF2 MDM2 NAB2 NGFR S100B
5 muscle MP:0005369 9.63 NGFR ACTC1 DES IGF2 MDM2 VIM
6 reproductive system MP:0005389 9.5 F13A1 FGF23 IGF2 MDM2 NAB2 STAT6
7 respiratory system MP:0005388 9.17 F13A1 FGF23 IGF2 NAB2 NGFR STAT6

Drugs & Therapeutics for Hemangiopericytoma, Malignant

Drugs for Hemangiopericytoma, Malignant (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
2
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
3
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
4
Lenograstim Approved, Investigational Phase 3,Phase 2 135968-09-1
5
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 498142 38904
6
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 50-18-0, 6055-19-2 2907
7
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 2019 457193
8
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
9
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
10
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
11
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
12
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
13 Alkylating Agents Phase 3,Phase 2,Phase 1
14 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
15 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
16 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
17
Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
18 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
19 Anti-Infective Agents Phase 3,Phase 2
20 Antimitotic Agents Phase 3,Phase 2
21 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
22 Antirheumatic Agents Phase 3,Phase 2,Phase 1
23 Etoposide phosphate Phase 3,Phase 2
24 Immunosuppressive Agents Phase 3,Phase 2
25 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
26
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
27
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
28
Bevacizumab Approved, Investigational Phase 2 216974-75-3
29
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
30
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
31
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
32
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
33
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
34
Nicotinamide Approved, Investigational, Nutraceutical Phase 2 98-92-0 936
35
Vatalanib Investigational Phase 2 212141-54-3 151194
36 Soblidotin Investigational Phase 2 149606-27-9
37
Camptothecin Experimental Phase 2 7689-03-4
38 Exatecan Investigational Phase 2 171335-80-1
39 Angiogenesis Inhibitors Phase 2
40 Angiogenesis Modulating Agents Phase 2
41 Antibodies Phase 2
42 Antibodies, Monoclonal Phase 2
43 Immunoglobulins Phase 2
44 Protein Kinase Inhibitors Phase 2,Phase 1
45 Micronutrients Phase 2
46 Nicotinic Acids Phase 2
47 Trace Elements Phase 2
48 Vitamin B Complex Phase 2
49 Vitamins Phase 2
50 Imatinib Mesylate Phase 1, Phase 2 220127-57-1 123596

Interventional clinical trials:

(show all 26)
# Name Status NCT ID Phase Drugs
1 Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma Unknown status NCT00334854 Phase 3 doxorubicin hydrochloride;ifosfamide
2 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
3 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
4 Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00003212 Phase 3 doxorubicin hydrochloride;ifosfamide
5 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
6 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
7 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
8 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3 doxorubicin hydrochloride;trabectedin
9 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2 temozolomide
10 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
11 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2 romidepsin
12 Vatalanib in Treating Patients With Recurrent or Progressive Meningioma Completed NCT00348790 Phase 2 vatalanib
13 S0505 Sorafenib in Treating Patients With Advanced Soft Tissue Sarcomas Completed NCT00217620 Phase 2 sorafenib
14 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
15 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2 trabectedin
16 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2 imatinib mesylate
17 Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00064220 Phase 2 soblidotin
18 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2 perifosine
19 Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00041249 Phase 2 brostallicin
20 Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00041236 Phase 2 exatecan mesylate
21 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
22 S9624 Ifosfamide in Treating Patients With Meningeal Tumors Terminated NCT00003292 Phase 2 ifosfamide
23 Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma Terminated NCT00740597 Phase 2
24 Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery Completed NCT00450736 Phase 1 celecoxib
25 Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00030784 Phase 1 ifosfamide;pegylated liposomal doxorubicin hydrochloride
26 Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX Unknown status NCT00900211

Search NIH Clinical Center for Hemangiopericytoma, Malignant

Cochrane evidence based reviews: hemangiopericytoma

Genetic Tests for Hemangiopericytoma, Malignant

Anatomical Context for Hemangiopericytoma, Malignant

MalaCards organs/tissues related to Hemangiopericytoma, Malignant:

41
Kidney, Liver, Thyroid, Lung, Spinal Cord, Brain, Prostate

Publications for Hemangiopericytoma, Malignant

Articles related to Hemangiopericytoma, Malignant:

(show top 50) (show all 737)
# Title Authors Year
1
Late Onset of Non-islet Cell Tumor Hypoglycemia Managed via Multidisciplinary Treatment in a Patient with a Solitary Fibrous Tumor. ( 29526941 )
2018
2
Mediastinal Solitary Fibrous Tumor Diagnosed by Endobronchial Ultrasound-Directed Biopsy. ( 28515414 )
2017
3
Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor. ( 27696380 )
2017
4
Scrotum solitary fibrous tumor: A case report and review of literature. ( 29310366 )
2017
5
Low tissue levels of miR-125b predict malignancy in solitary fibrous tumors of the pleura. ( 28253927 )
2017
6
Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report. ( 29201988 )
2017
7
Synchronous pancreatic and pulmonary metastases from solitary fibrous tumor of the pleura: report of a case. ( 28009423 )
2017
8
Solitary Fibrous Tumor of Central Nervous System: Clinical and Prognostic Study of 24 Cases. ( 28017751 )
2017
9
Solitary fibrous tumor of the lacrimal gland mimicking pleomorphic adenoma. ( 28832740 )
2017
10
Solitary fibrous tumor of the pleura with associated Doege-Potter syndrome. ( 27376978 )
2016
11
[Hypoglycemia in a solitary fibrous tumor of the liver]. ( 27108555 )
2016
12
Malignant giant solitary fibrous tumor of the pleura metastatic to the thyroid gland. ( 27133228 )
2016
13
Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor. ( 27134683 )
2016
14
Different clinical and radiological features of solitary fibrous tumor of the pleura: Report of two cases. ( 26933312 )
2016
15
Non-islet cell tumor hypoglycemia caused by intrathoracic solitary fibrous tumor: a case report. ( 27061182 )
2016
16
Integrally calcified solitary fibrous tumor in the retroperitoneum: a case report and review of the literature. ( 26943690 )
2016
17
Bone Scintigraphy in a Patient With Giant Malignant Solitary Fibrous Tumor of the Pleura. ( 26914570 )
2016
18
Diagnostic Utility of STAT6 Immunohistochemistry in the Diagnosis of Fat-forming Solitary Fibrous Tumors. ( 25517867 )
2016
19
Myoepithelioma-like Tumor of the Vulvar Region Presenting as a Nonmyxoid Spindle-Cell Neoplasm: A Potential Histologic Mimicker of Solitary Fibrous Tumor. ( 26959696 )
2016
20
Analysis of NAB2-STAT6 Gene Fusion in 17 Cases of Meningeal Solitary Fibrous Tumor/Hemangiopericytoma: Review of the Literature. ( 26927892 )
2016
21
Solitary Fibrous Tumor of the Kidney: A Case Report and Literature Review. ( 27014524 )
2016
22
Hemangiopericytoma/solitary fibrous tumor of the greater omentum: A case report and review of the literature. ( 27138450 )
2016
23
The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors. ( 26686340 )
2016
24
Giant Solitary Fibrous Tumor of the Buttock. ( 26958572 )
2016
25
TERT promoter mutations and prognosis in solitary fibrous tumor. ( 27562490 )
2016
26
Clinical analysis of 47 cases of solitary fibrous tumor. ( 27698815 )
2016
27
Variable Solitary Fibrous Tumor Locations: CT and MR Imaging Features. ( 27043668 )
2016
28
Intracranial solitary fibrous tumor/ hemangiopericytoma with osteoclast-like multinucleated giant cells: comparison with giant cell-rich solitary fibrous tumor. ( 27049065 )
2016
29
A recurrent solitary fibrous tumor of the thigh with malignant transformation: A case report. ( 26967903 )
2016
30
The Utility of STAT6 and ALDH1 Expression in the Differential Diagnosis of Solitary Fibrous Tumor vs Prostate Specific Stromal Neoplasms. ( 27068523 )
2016
31
Clinicopathological differences between variants of the NAB2-STAT6 fusion gene in solitary fibrous tumors of the meninges and extra-central nervous system. ( 27271270 )
2016
32
Clinicopathologic and immunohistochemical features of five new cases of solitary fibrous tumor of the oral cavity. ( 26852825 )
2016
33
'Papillary' solitary fibrous tumor/hemangiopericytoma with nuclear STAT6 expression and NAB2-STAT6 fusion. ( 26746203 )
2016
34
Temporal Malignant Solitary Fibrous Tumor. ( 26927758 )
2016
35
A case of extrapleural solitary fibrous tumor of the thigh with eight years follow-up. ( 27151726 )
2016
36
Solitary Fibrous Tumor/Hemangiopericytoma Dichotomy Revisited: A Restless Family of Neoplasms in the CNS. ( 26849816 )
2016
37
NAB2-STAT6 Gene Fusion in Meningeal Hemangiopericytoma and Solitary Fibrous Tumor. ( 26883114 )
2016
38
Histopathologically malignant solitary fibrous tumor of the skin: a report of an unusual case. ( 27062638 )
2016
39
STAT6 Loss in Dedifferentiated Solitary Fibrous Tumor. ( 27189111 )
2016
40
Extensive bone remodeling from a solitary fibrous tumor of the cervical spine. ( 26997109 )
2016
41
A subset of solitary fibrous tumors express nuclear PAX8 and PAX2: a potential diagnostic pitfall. ( 26404914 )
2016
42
NAB2-STAT6 fusion gene analysis in two cases of meningeal solitary fibrous tumor/hemangiopericytoma with late distant metastases. ( 25893823 )
2015
43
A solitary fibrous tumor of the upper limb. ( 25719592 )
2015
44
Solitary fibrous tumor of the pleura: Can computed tomography features help predict malignancy? A series of 56 patients with histopathological correlates. ( 26542536 )
2015
45
[Two Cases of Primary Intracranial Solitary Fibrous Tumor:Genetic Examination of <i>NAB2-STAT6</i> Fusion and Its Association with Hemangiopericytoma]. ( 26136329 )
2015
46
A Pleural Solitary Fibrous Tumor, Multiple Gastrointestinal Stromal Tumors, Moyamoya Disease, and Hyperparathyroidism in a Patient Associated with NF1. ( 26442164 )
2015
47
Solitary Fibrous Tumor of the Stomach Treated with Laparoscopic and Endoscopic Cooperative Surgery. ( 26369266 )
2015
48
Intradural solitary fibrous tumor of the lumbar spine: a distinctive case report. ( 25648160 )
2015
49
A case of solitary fibrous tumor arising from the palatine tonsil. ( 25738718 )
2015
50
A GRIA2 and PAX8-positive renal solitary fibrous tumor with NAB2-STAT6 gene fusion. ( 26337721 )
2015

Variations for Hemangiopericytoma, Malignant

Cosmic variations for Hemangiopericytoma, Malignant:

9
(show all 15)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM584 NRAS soft tissue,blood vessel,haemangioma,capillary c.182A>G p.Q61R 1:114713908-114713908 6
2 COSM580 NRAS soft tissue,blood vessel,haemangioma,capillary c.181C>A p.Q61K 1:114713909-114713909 6
3 COSM529 KRAS soft tissue,blood vessel,haemangioma,capillary c.37G>C p.G13R 12:25245348-25245348 6
4 COSM521 KRAS soft tissue,blood vessel,haemangioma,capillary c.35G>A p.G12D 12:25245350-25245350 6
5 COSM516 KRAS soft tissue,blood vessel,haemangioma,capillary c.34G>T p.G12C 12:25245351-25245351 6
6 COSM487 HRAS soft tissue,blood vessel,haemangioma,capillary c.37G>A p.G13S 11:534286-534286 6
7 COSM6503574 HRAS soft tissue,blood vessel,haemangioma,capillary c.145G>A p.E49K 11:533911-533911 6
8 COSM486 HRAS soft tissue,blood vessel,haemangioma,capillary c.37G>C p.G13R 11:534286-534286 6
9 COSM6503575 HRAS soft tissue,blood vessel,haemangioma,capillary c.44G>A p.G15D 11:534279-534279 6
10 COSM499 HRAS soft tissue,blood vessel,haemangioma,capillary c.182A>G p.Q61R 11:533874-533874 6
11 COSM6503576 HRAS soft tissue,blood vessel,haemangioma,capillary c.100C>T p.P34S 11:534223-534223 6
12 COSM52975 GNAQ soft tissue,blood vessel,haemangioma,capillary c.548G>A p.R183Q 9:77797577-77797577 6
13 COSM21651 GNA11 soft tissue,blood vessel,haemangioma,capillary c.547C>T p.R183C 19:3115014-3115014 6
14 COSM476 BRAF soft tissue,blood vessel,haemangioma,capillary c.1799T>A p.V600E 7:140753336-140753336 6
15 COSM449 BRAF soft tissue,blood vessel,haemangioma,capillary c.1391G>A p.G464E 7:140781617-140781617 6

Expression for Hemangiopericytoma, Malignant

Search GEO for disease gene expression data for Hemangiopericytoma, Malignant.

Pathways for Hemangiopericytoma, Malignant

Pathways related to Hemangiopericytoma, Malignant according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.33 DES FGF23 IGF2 MDM2 MUC1 NGFR
2 11.95 ACTC1 DES MUC1 VIM
3 10.99 ACTC1 DES VIM
4 10.98 F13A1 MUC1 STAT6 VIM

GO Terms for Hemangiopericytoma, Malignant

Biological processes related to Hemangiopericytoma, Malignant according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.46 F13A1 MUC1 STAT6 VIM
2 intermediate filament organization GO:0045109 9.32 DES VIM
3 response to magnesium ion GO:0032026 9.26 FGF23 MDM2
4 negative regulation of neuron projection development GO:0010977 9.13 MDM2 NGFR VIM
5 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Molecular functions related to Hemangiopericytoma, Malignant according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.17 DES HACL1 MDM2 NAB2 S100B STAT6

Sources for Hemangiopericytoma, Malignant

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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