MCID: HMP006
MIFTS: 49

Hemiplegic Migraine

Categories: Eye diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Hemiplegic Migraine

MalaCards integrated aliases for Hemiplegic Migraine:

Name: Hemiplegic Migraine 54 38 74
Migraine Hemiplegic 56

Classifications:



External Ids:

KEGG 38 H00775
UMLS 74 C0270862

Summaries for Hemiplegic Migraine

NIH Rare Diseases : 54 Hemiplegic migraine (HM) is a rare type of migraine with aura that occurs with motor weakness during the aura. There are two types of HM which are distinguished based on the family history: familial hemiplegic migraine (FHM, in which at least one other family member has the condition) and sporadic hemiplegic migraine (SHM, in which there is no family history). Signs and symptoms vary but may include visual disturbances, sensory loss, difficulty with speech, weakness on one side of the body, confusion, and impaired consciousness. Severe attacks may occur in both types with prolonged hemiplegia, coma, fever and/or seizures. FHM may be caused by a mutation in any of several genes and is inherited in an autosomal dominant manner.

MalaCards based summary : Hemiplegic Migraine, also known as migraine hemiplegic, is related to sporadic hemiplegic migraine and familial or sporadic hemiplegic migraine. An important gene associated with Hemiplegic Migraine is ATP1A2 (ATPase Na+/K+ Transporting Subunit Alpha 2), and among its related pathways/superpathways are MAPK signaling pathway and Calcium signaling pathway. The drugs Topiramate and Hypoglycemic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and testes, and related phenotypes are Increased viability with SS1P at EC90 and behavior/neurological

Wikipedia : 77 Hemiplegic migraine or Hemiplegic migraine headache is a rare and serious subtype of classical migraine... more...

Related Diseases for Hemiplegic Migraine

Diseases in the Hemiplegic Migraine family:

Migraine, Familial Hemiplegic, 1 Migraine, Familial Hemiplegic, 2
Migraine, Familial Hemiplegic, 3 Familial Hemiplegic Migraine
Sporadic Hemiplegic Migraine Familial or Sporadic Hemiplegic Migraine

Diseases related to Hemiplegic Migraine via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 74, show less)
# Related Disease Score Top Affiliating Genes
1 sporadic hemiplegic migraine 34.6 ATP1A2 CACNA1A SCN1A
2 familial or sporadic hemiplegic migraine 33.9 ATP1A2 CACNA1A PRRT2 SCN1A
3 familial hemiplegic migraine 33.2 ATP1A2 ATP1A3 CACNA1A CALCA NOTCH3 OPRM1
4 migraine with or without aura 1 32.2 ATP1A2 CACNA1A CALCA NOTCH3 PRRT2 SCN1A
5 episodic ataxia 31.0 ATP1A2 CACNA1A PRRT2
6 aceruloplasminemia 30.6 ATP1A3 CACNA1A SLC2A1
7 epilepsy 30.4 ATP1A2 ATP1A3 CACNA1A PRRT2 SCN1A SLC2A1
8 migraine without aura 30.4 ATP1A2 CACNA1A SCN1A
9 headache 30.3 ATP1A2 CACNA1A SCN1A
10 migraine with aura 30.3 ATP1A2 CACNA1A NOTCH3 PRRT2 SCN1A
11 alternating hemiplegia of childhood 30.3 ATP1A2 ATP1A3 CACNA1A CALCA SLC2A1
12 hemiplegia 30.3 ATP1A2 ATP1A3 CACNA1A CALCA SCN1A SLC2A1
13 torticollis 30.2 CACNA1A PRRT2
14 dystonia 30.0 ATP1A3 GNB1 PRRT2 SLC2A1
15 migraine, familial hemiplegic, 1 12.5
16 migraine, familial hemiplegic, 2 12.5
17 migraine, familial hemiplegic, 3 12.5
18 alternating hemiplegia of childhood 1 11.7
19 convulsions, familial infantile, with paroxysmal choreoathetosis 11.3
20 alternating hemiplegia of childhood 2 11.3
21 phosphoglycerate kinase deficiency 11.3
22 depression 10.5
23 ocular motor apraxia 10.5
24 ataxia and polyneuropathy, adult-onset 10.4
25 encephalopathy 10.4
26 spinocerebellar ataxia 6 10.4
27 episodic ataxia, type 2 10.3
28 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 10.3
29 generalized epilepsy with febrile seizures plus, type 2 10.3 LOC102724058 SCN1A
30 generalized epilepsy with febrile seizures plus, type 1 10.3 LOC102724058 SCN1A
31 sturge-weber syndrome 10.2
32 moyamoya disease 1 10.2
33 seizures, benign familial infantile, 2 10.2
34 patent foramen ovale 10.2
35 autosomal dominant cerebellar ataxia 10.2
36 pathologic nystagmus 10.2
37 weber syndrome 10.2
38 glut1 deficiency syndrome 2 10.2 PRRT2 SLC2A1
39 paroxysmal choreoathetosis 10.1 PRRT2 SLC2A1
40 cystic fibrosis 10.1
41 retinal degeneration 10.1
42 seizure disorder 10.1
43 dystonia, dopa-responsive 10.1 ATP1A3 PRRT2 SLC2A1
44 early onset absence epilepsy 10.0 PRRT2 SLC2A1
45 cluster headache 10.0 CACNA1A CALCA
46 focal epilepsy 10.0 LOC102724058 SCN1A SLC2A1
47 pulmonary hypertension, primary, 1 10.0
48 pulmonary arteriovenous fistulas 10.0
49 cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss 10.0
50 yemenite deaf-blind hypopigmentation syndrome 10.0
51 orthostatic intolerance 10.0
52 brain injury 10.0
53 traumatic brain injury 10.0
54 crest syndrome 10.0
55 arteriovenous malformation 10.0
56 status epilepticus 10.0
57 ischemia 10.0
58 mood disorder 10.0
59 erdheim-chester disease 10.0
60 intracranial embolism 10.0
61 intracranial hypertension 10.0
62 cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorinural hearing loss 10.0
63 hemicrania continua 10.0
64 lipogranulomatosis 10.0
65 migraine with brainstem aura 10.0
66 pulmonary arteriovenous malformation 10.0
67 spastic paraparesis 10.0
68 tremor 10.0
69 cerebral atrophy 10.0
70 febrile seizures 10.0
71 thyrotoxic periodic paralysis 10.0 ATP1A2 ATP1B1 ATP1B2
72 epilepsy, idiopathic generalized 10.0 CACNA1A OPRM1 SCN1A SLC2A1
73 alacrima, achalasia, and mental retardation syndrome 9.9 CACNA1A GNB1 SCN1A SLC2A1
74 visual epilepsy 9.8 ATP1A3 GNB1 PRRT2 SCN1A SLC2A1

Graphical network of the top 20 diseases related to Hemiplegic Migraine:



Diseases related to Hemiplegic Migraine

Symptoms & Phenotypes for Hemiplegic Migraine

GenomeRNAi Phenotypes related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

27 (showing 1, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability with SS1P at EC90 GR00376-A-1 8.8 ATP1A3 GNAI2 GNB1

MGI Mouse Phenotypes related to Hemiplegic Migraine:

47 (showing 5, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.1 ATP1A2 ATP1A3 ATP1B2 CACNA1A GNAI2 GNB1
2 mortality/aging MP:0010768 10.07 ATP1A2 ATP1A3 ATP1B1 ATP1B2 CACNA1A GNAI2
3 nervous system MP:0003631 9.93 ATP1A2 ATP1A3 ATP1B2 CACNA1A GNAI2 GNB1
4 normal MP:0002873 9.56 ATP1A2 ATP1B1 CACNA1A GNAI2 NOTCH3 OPRM1
5 respiratory system MP:0005388 9.23 ATP1A2 ATP1A3 ATP1B1 CACNA1A GNAI2 GNB1

Drugs & Therapeutics for Hemiplegic Migraine

Drugs for Hemiplegic Migraine (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 15, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 2, Phase 3 97240-79-4 5284627
2 Hypoglycemic Agents Phase 2, Phase 3
3 Anticonvulsants Phase 2, Phase 3
4
Nitroglycerin Approved, Investigational Not Applicable 55-63-0 4510
5
Salmon Calcitonin Approved, Investigational Not Applicable 47931-85-1 16129616
6
Pancrelipase Approved, Investigational 53608-75-6
7
Calcium Approved, Nutraceutical Not Applicable 7440-70-2 271
8
Calcitonin gene-related peptide Investigational Not Applicable 83652-28-2
9 Vasodilator Agents Not Applicable
10 Hormones Not Applicable
11 Bone Density Conservation Agents Not Applicable
12 Calcium, Dietary Not Applicable
13 Katacalcin Not Applicable
14 calcitonin Not Applicable
15 pancreatin

Interventional clinical trials:

(showing 9, show less)
# Name Status NCT ID Phase Drugs
1 Dose Comparison Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine Completed NCT00131443 Phase 2, Phase 3 Topiramate
2 A Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine Completed NCT00158002 Phase 2 Topiramate
3 Continuous Treatment Study of Topiramate in Migraine Participants Completed NCT01799590 Phase 2 Topiramate
4 Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Completed NCT00541736 Not Applicable Nitroglycerine
5 Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2. Completed NCT00358839 Not Applicable CGRP
6 Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2 Completed NCT00257985 Not Applicable GTN
7 Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA) Completed NCT00687947 Not Applicable CGRP
8 Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines Recruiting NCT00727974
9 Pilot Study of Acute Stroke Using the Brainpulse™ Recruiting NCT03235271

Search NIH Clinical Center for Hemiplegic Migraine

Genetic Tests for Hemiplegic Migraine

Anatomical Context for Hemiplegic Migraine

MalaCards organs/tissues related to Hemiplegic Migraine:

42
Brain, Bone, Testes, Trigeminal Ganglion, Smooth Muscle, Cerebellum, Cortex

Publications for Hemiplegic Migraine

Articles related to Hemiplegic Migraine:

(showing 443, show less)
# Title Authors Year
1
Migrainous Infarction in a Patient With Sporadic Hemiplegic Migraine and Cystic Fibrosis: A 99mTc-HMPAO Brain SPECT Study. ( 30620050 )
2019
2
Familial hemiplegic migraine in a child with seizure disorder: clinical history is the key to diagnosis. ( 30914414 )
2019
3
A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. ( 31053037 )
2019
4
Mouse Models of Familial Hemiplegic Migraine for Studying Migraine Pathophysiology. ( 31092180 )
2019
5
Neuronal injuries evidenced by transient cortical magnetic resonance enhancement in hemiplegic migraine: A case report. ( 30092648 )
2019
6
The Effect of Onabotulinum Toxin on Aura Frequency and Severity in Patients With Hemiplegic Migraine - A Comment. ( 30575970 )
2019
7
Sporadic Hemiplegic Migraine with Psychotic Episode and MRI Abnormalities - Therapeutic Dilemma: a Case Report. ( 30948700 )
2019
8
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. ( 28445178 )
2018
9
Ten years of follow-up in a large family with familial hemiplegic migraine type 1: Clinical course and implications for treatment. ( 28856914 )
2018
10
Mild Traumatic Brain Injury in a High School Football Player With Familial Hemiplegic Migraine: A Case Report. ( 28918117 )
2018
11
Enhanced susceptibility to cortical spreading depression in two types of Na+,K+-ATPase α2 subunit-deficient mice as a model of familial hemiplegic migraine 2. ( 29041816 )
2018
12
Smooth muscle Ca2+ sensitization causes hypercontractility of middle cerebral arteries in mice bearing the familial hemiplegic migraine type 2 associated mutation. ( 29513112 )
2018
13
Gain of function of sporadic/familial hemiplegic migraine-causing SCN1A mutations: Use of an optimized cDNA. ( 29986598 )
2018
14
Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine. ( 30038559 )
2018
15
Multimodal imaging findings during severe attacks of familial hemiplegic migraine type 2. ( 30097147 )
2018
16
Ultrastructural changes in microvessels in familial hemiplegic migraine with CACNA1A mutation. ( 30148448 )
2018
17
Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report. ( 30498473 )
2018
18
Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications. ( 28058944 )
2018
19
Reversible cortical thickening in hemiplegic migraine. ( 28120619 )
2018
20
Brain atrophy following hemiplegic migraine attacks. ( 28750589 )
2018
21
Two novel families with hemiplegic migraine caused by recurrent SCN1A mutation p.F1499L. ( 29145747 )
2018
22
Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation. ( 29343472 )
2018
23
Ocular Dipping in a Patient With Hemiplegic Migraine. ( 29384561 )
2018
24
The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families. ( 29486580 )
2018
25
Hemiplegic migraine and stroke in Mary Shelley. ( 29553379 )
2018
26
The Effect of OnabotulinumtoxinA on Aura Frequency and Severity in Patients With Hemiplegic Migraine: Case Series of 11 Patients. ( 29762872 )
2018
27
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. ( 29867740 )
2018
28
Pediatric sporadic hemiplegic migraine (ATP1A2 gene): a case report and brief literature review. ( 29904856 )
2018
29
Hemiplegic Migraine as the Initial Presentation of Biopsy Positive Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy. ( 30027023 )
2018
30
Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation. ( 27226003 )
2017
31
A novel SCN1A mutation identified in a Chinese family with familial hemiplegic migraine: A case report. ( 27919014 )
2017
32
Identification of the first in Poland CACNA1A gene mutation in familial hemiplegic migraine. Case report. ( 28169007 )
2017
33
Hyperpolarization-activated current Ih in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1. ( 28363781 )
2017
34
The α2β2 isoform combination dominates the astrocytic Na+ /K+ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation. ( 28787093 )
2017
35
Cerebellar Atrophy and Changes in Cytokines Associated with the CACNA1A R583Q Mutation in a Russian Familial Hemiplegic Migraine Type 1 Family. ( 28900389 )
2017
36
Postoperative Hemiplegic Migraine After a Laparoscopic Cholecystectomy: A Case Report. ( 28045726 )
2017
37
The genetic relationship between epilepsy and hemiplegic migraine. ( 28479855 )
2017
38
Stroke-like attack: first episode of sporadic hemiplegic migraine. ( 28527090 )
2017
39
Acute Intravenous Calcium Antagonist for Suspected Hemiplegic Migraine - A Case Story. ( 28559833 )
2017
40
De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. ( 28593511 )
2017
41
First Episode of Hemiplegic Migraine. ( 28601240 )
2017
42
Erratum to: De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. ( 28702766 )
2017
43
Sulcal hyperintensity mimicking subarachnoid hemorrhage in the context of hemiplegic migraine. ( 29236896 )
2017
44
Perfusion and pH MRI in familial hemiplegic migraine with prolonged aura. ( 25948653 )
2016
45
Early-onset familial hemiplegic migraine due to a novel SCN1A mutation. ( 26763045 )
2016
46
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. ( 26911348 )
2016
47
Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine. ( 27175010 )
2016
48
Activity-dependent calcium, oxygen, and vascular responses in a mouse model of familial hemiplegic migraine type 1. ( 27314908 )
2016
49
Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1. ( 27346147 )
2016
50
Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2. ( 27354390 )
2016
51
Time course of downbeat positioning nystagmus in familial hemiplegic migraine type 1 treated with acetazolamide. ( 27538634 )
2016
52
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation. ( 27818813 )
2016
53
A case report of sporadic hemiplegic migraine associated cerebral hypoperfusion: comparison of arterial spin labeling and dynamic susceptibility contrast perfusion MR imaging. ( 26250760 )
2016
54
Sporadic hemiplegic migraine and giant tumefactive perivascular space: Is there an association? ( 26696413 )
2016
55
A retrospective analysis of triptan and dhe use for basilar and hemiplegic migraine. ( 27062528 )
2016
56
Clinical and electroencephalographic abnormalities during the full duration of a sporadic hemiplegic migraine attack. ( 27155821 )
2016
57
Hemiplegic migraine and late-onset photosensitive epileptic seizures. ( 27406575 )
2016
58
Hemiplegic Migraine Presenting with Prolonged Somnolence: A Case Report. ( 27790126 )
2016
59
Prevalence of lifetime depression in a large hemiplegic migraine cohort. ( 27807184 )
2016
60
Intermittent Theta Slowings in Contralateral Side of Weakness after Sleep Deprivation on Spot EEG in Sporadic Hemiplegic Migraine. ( 28101483 )
2016
61
A novel SLC2A1 mutation linking hemiplegic migraine with alternating hemiplegia of childhood. ( 24824604 )
2015
62
Novel frameshift mutation in the CACNA1A gene causing a mixed phenotype of episodic ataxia and familiar hemiplegic migraine. ( 25468264 )
2015
63
Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2. ( 25411546 )
2015
64
Stress hormone corticosterone enhances susceptibility to cortical spreading depression in familial hemiplegic migraine type 1 mutant mice. ( 25447936 )
2015
65
Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice. ( 25481823 )
2015
66
Abnormal cortical synaptic transmission in CaV2.1 knockin mice with the S218L missense mutation which causes a severe familial hemiplegic migraine syndrome in humans. ( 25741235 )
2015
67
Familial hemiplegic migraine type 1 associated with parkinsonism: a case report. ( 25969684 )
2015
68
Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice. ( 26032020 )
2015
69
Familial Hemiplegic Migraine and Recurrent Episodes of Psychosis: A Case Report. ( 26087244 )
2015
70
Cortical spreading depression and familial hemiplegic migraine 2015. ( 28132368 )
2015
71
Concordant occipital and supraorbital neurostimulation therapy for hemiplegic migraine; initial experience; a case series. ( 25688595 )
2015
72
Plasma metabolic profiling after cortical spreading depression in a transgenic mouse model of hemiplegic migraine by capillary electrophoresis--mass spectrometry. ( 25856790 )
2015
73
CAPOS syndrome and hemiplegic migraine in a novel pedigree with the specific ATP1A3 mutation. ( 26453127 )
2015
74
P016. Congenital ataxia, hemiplegic migraine due to a novel mutation of CACNA1A: a case report. ( 28132242 )
2015
75
P068. A suggestive case of hemiplegic migraine: a diagnostic challenge. ( 28132306 )
2015
76
Sturge-Weber syndrome with late onset hemiplegic migraine-like attacks and progressive unilateral cerebral atrophy. ( 24045571 )
2014
77
A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy. ( 23918834 )
2014
78
RNA expression profiling in brains of familial hemiplegic migraine type 1 knock-in mice. ( 23985897 )
2014
79
Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene. ( 24096472 )
2014
80
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. ( 24136331 )
2014
81
Delayed recovery post anesthesia: an atypical presentation of familial hemiplegic migraine. ( 24347352 )
2014
82
Differential trigeminovascular nociceptive responses in the thalamus in the familial hemiplegic migraine 1 knock-in mouse: a Fos protein study. ( 24355314 )
2014
83
Pharmacological correction of gating defects in the voltage-gated Ca(v)2.1 Ca²⁺ channel due to a familial hemiplegic migraine mutation. ( 24411734 )
2014
84
Familial hemiplegic migraine treated by sodium valproate and lamotrigine. ( 24443394 )
2014
85
A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1. ( 24583041 )
2014
86
Familial hemiplegic migraine due to L263V SCN1A mutation: discordance for epilepsy between two kindreds from Douro Valley. ( 24646837 )
2014
87
Biochemical characterization of sporadic/familial hemiplegic migraine mutations. ( 24704353 )
2014
88
Two novel SCN1A mutations identified in families with familial hemiplegic migraine. ( 24707016 )
2014
89
Familial hemiplegic migraine: a model for the genetic studies of migraine. ( 24707017 )
2014
90
Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i. ( 24849341 )
2014
91
The prevalence of familial hemiplegic migraine with cerebellar ataxia and spinocerebellar ataxia type 6 in Portugal. ( 24898624 )
2014
92
Familial hemiplegic migraine and spreading depression. ( 25143767 )
2014
93
Repeated encephalopathy and hemicerebral atrophy in a patient with familial hemiplegic migraine type 1. ( 25274239 )
2014
94
An altered GABA-A receptor function in spinocerebellar ataxia type 6 and familial hemiplegic migraine type 1 associated with the CACNA1A gene mutation. ( 26675662 )
2014
95
Calcium channels and synaptic transmission in familial hemiplegic migraine type 1 animal models. ( 28509957 )
2014
96
Sporadic hemiplegic migraine with permanent neurological deficits. ( 24117121 )
2014
97
Pediatric hemiplegic migraine: role of multiple MRI techniques in evaluation of reversible hypoperfusion. ( 24142848 )
2014
98
Rare clinical findings in a patient with sporadic hemiplegic migraine: FDG-PET provides diminished brain metabolism at 10-year follow-up. ( 24270521 )
2014
99
Benefit of carbamazepine in a patient with hemiplegic migraine associated with PRRT2 mutation. ( 24506539 )
2014
100
Hemiplegic migraine: neuroimaging findings during a hemiplegic migraine attack. ( 24512003 )
2014
101
Biochemical changes in the brain of hemiplegic migraine patients measured with 7 tesla 1H-MRS. ( 24651393 )
2014
102
Changes in (99m)Tc-ECD SPECT and magnetic resonance angiography with sporadic hemiplegic migraine in a child. ( 24662647 )
2014
103
Arterial surgery for sporadic hemiplegic migraine: preliminary results. ( 24703384 )
2014
104
Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A. ( 24836863 )
2014
105
Functional analysis of human Na(+)/K(+)-ATPase familial or sporadic hemiplegic migraine mutations expressed in Xenopus oocytes. ( 24921013 )
2014
106
PRRT2 and hemiplegic migraine: a complex association. ( 24928127 )
2014
107
Hemiplegic migraine: An atypical presentation of Moyamoya disease. ( 25538508 )
2014
108
Magnetic resonance angiography evidence of vasospasm in children with suspected acute hemiplegic migraine. ( 23594822 )
2014
109
Effects of LPS on P2X3 receptors of trigeminal sensory neurons and macrophages from mice expressing the R192Q Cacna1a gene mutation of familial hemiplegic migraine-1. ( 22836594 )
2013
110
TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine. ( 23326332 )
2013
111
The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels. ( 23430985 )
2013
112
Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models. ( 23561701 )
2013
113
The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1). ( 23577145 )
2013
114
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. ( 23761507 )
2013
115
Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions. ( 23954377 )
2013
116
Monozygotic twin sisters discordant for familial hemiplegic migraine. ( 24041236 )
2013
117
Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects. ( 24101488 )
2013
118
Hemiplegic migraine with reversible cerebral vasoconstriction caused by ATP1A2 mutations. ( 23821026 )
2013
119
Possible effect of corticoids on hemiplegic attacks in severe hemiplegic migraine. ( 23831250 )
2013
120
Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy. ( 23838748 )
2013
121
Sporadic hemiplegic migraine in a Nigerian woman. ( 24005593 )
2013
122
Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations. ( 24396618 )
2013
123
Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies. ( 24498617 )
2013
124
A pediatric sporadic hemiplegic migraine case with perfusion abnormality in perfusion MRI and Diamox 99mTc-HMPAO SPECT. ( 22547402 )
2013
125
PRRT2 mutation causes paroxysmal kinesigenic dyskinesia and hemiplegic migraine in monozygotic twins. ( 23182655 )
2013
126
Familial and sporadic hemiplegic migraine: diagnosis and treatment. ( 23203776 )
2013
127
Impact of 99mTc-HMPAO brain perfusion scan in the diagnosis of hemiplegic migraine. ( 23334140 )
2013
128
May a suspicious psychiatric disorder hide sporadic hemiplegic migraine? Genetic test as prompting factor for diagnosis. ( 23397224 )
2013
129
Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine. ( 23398611 )
2013
130
Cerebellar ataxia, hemiplegic migraine, and related phenotypes due to a CACNA1A missense mutation: 12-year follow-up of a large Portuguese family. ( 23407676 )
2013
131
Transient unilateral spatial neglect during aura in a woman with sporadic hemiplegic migraine. ( 23674829 )
2013
132
The diagnostic role for susceptibility-weighted MRI during sporadic hemiplegic migraine. ( 23766355 )
2013
133
Recurrent transient hemiparesis in a patient with a giant persisting Eustachian valve and patent foramen ovale: atypical hemiplegic migraine or paradoxical cerebral embolism? ( 23812203 )
2013
134
Posttraumatic dystonia and hemiplegic migraine: different expressions of neuronal hyperexcitability? ( 22217613 )
2012
135
PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. ( 23077024 )
2012
136
Long-term outcome of cognitive functions, emotional behavior, and quality of life in a family with familial hemiplegic migraine. ( 22596110 )
2012
137
Stroke and familial hemiplegic migraine. ( 22608661 )
2012
138
Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2). ( 22661290 )
2012
139
A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation. ( 22759692 )
2012
140
Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children. ( 22883286 )
2012
141
Familial hemiplegic migraine with prolonged global aura: follow-up findings of subtraction ictal SPECT co-registered to MRI (SISCOM). ( 22933508 )
2012
142
Presynaptic CaV2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held. ( 22956801 )
2012
143
Familial hemiplegic migraine with prolonged coma and cerebellar atrophy: CACNA1A T666M mutation in a Korean family. ( 22969264 )
2012
144
CaV2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis. ( 22074995 )
2012
145
Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine. ( 22117059 )
2012
146
Effects of familial hemiplegic migraine type 1 mutation T666M on voltage-gated calcium channel activities in trigeminal ganglion neurons. ( 22190617 )
2012
147
Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels. ( 22549042 )
2012
148
Late cytotoxic edema in 2 children with hemiplegia: hemiplegic migraine or stroke? ( 22404149 )
2012
149
Perfusion-weighted MR imaging in persistent hemiplegic migraine. ( 21833737 )
2012
150
Sporadic hemiplegic migraine presenting as acute encephalopathy. ( 22136990 )
2012
151
Coexistence of hemiplegic migraine with SUNCT or SUNA: a case series. ( 22238357 )
2012
152
Sporadic hemiplegic migraine with normal imaging as the initial manifestation of CADASIL. ( 22250206 )
2012
153
Safety and efficacy of flunarizine in childhood migraine: 11 years' experience, with emphasis on its effect in hemiplegic migraine. ( 22268377 )
2012
154
Sporadic hemiplegic migraine. ( 22410518 )
2012
155
Migraine-induced epistaxis and sporadic hemiplegic migraine: unusual features in the same patient. ( 22807908 )
2012
156
Familial PRRT2 mutation with heterogeneous paroxysmal disorders including paroxysmal torticollis and hemiplegic migraine. ( 22845787 )
2012
157
PRRT2 mutations cause hemiplegic migraine. ( 23077016 )
2012
158
PRRT2 mutations in familial infantile seizures, paroxysmal dyskinesia, and hemiplegic migraine. ( 23077026 )
2012
159
Prolonged symptoms in sporadic hemiplegic migraine: aura or migrainous infarction? ( 23196733 )
2012
160
One case of sporadic hemiplegic migraine with multiple pulmonary arteriovenous malformation. ( 21246241 )
2011
161
Genetic diagnosis and acetazolamide treatment of familial hemiplegic migraine. ( 20542393 )
2011
162
Habituation of evoked responses is greater in patients with familial hemiplegic migraine than in controls: a contrast with the common forms of migraine. ( 20727009 )
2011
163
Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine. ( 21457239 )
2011
164
Sporadic and familial hemiplegic migraine: pathophysiological mechanisms, clinical characteristics, diagnosis, and management. ( 21458376 )
2011
165
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. ( 21490217 )
2011
166
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2. ( 21731499 )
2011
167
Trigger factors for familial hemiplegic migraine. ( 21784774 )
2011
168
Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse. ( 21893556 )
2011
169
Transient nonverbal learning disorder in a child suffering from Familial Hemiplegic Migraine. ( 21908445 )
2011
170
A long-term follow-up study of 18 patients with sporadic hemiplegic migraine. ( 20974584 )
2011
171
The digiti quinti sign in hemiplegic migraine. ( 20974599 )
2011
172
A novel mutation in CACNA1A associated with hemiplegic migraine, cerebellar dysfunction and late-onset cognitive decline. ( 21035146 )
2011
173
Multimodal neuroimaging in a child with sporadic hemiplegic migraine: a contribution to understanding pathogenesis. ( 21172953 )
2011
174
Prolonged sporadic hemiplegic migraine associated with a novel de novo missense ATP1A2 gene mutation. ( 21352219 )
2011
175
The genetic features of 24 patients affected by familial and sporadic hemiplegic migraine. ( 21533730 )
2011
176
Hemiplegic migraine aura begins with cerebral hypoperfusion: imaging in the acute phase. ( 21797860 )
2011
177
Hemiplegic migraine, seizures, progressive spastic paraparesis, mood disorder, and coma in siblings with low systemic serotonin. ( 22013141 )
2011
178
Acute striatal necrosis in hemiplegic migraine with de novo CACNA1A mutation. ( 22082423 )
2011
179
Sporadic hemiplegic migraine with seizures and transient MRI abnormalities. ( 22937333 )
2011
180
Sporadic hemiplegic migraine and CREST syndrome. ( 20130953 )
2010
181
Link between confusional migraine, hemiplegic migraine and episodic ataxia type 2: hypothesis, family genealogy, gene typing and classification. ( 19624685 )
2010
182
Coexisting typical migraine in familial hemiplegic migraine. ( 20157162 )
2010
183
Management of sporadic and familial hemiplegic migraine. ( 20187861 )
2010
184
Insights into migraine mechanisms and CaV2.1 calcium channel function from mouse models of familial hemiplegic migraine. ( 20194127 )
2010
185
Partially reversible cortical metabolic dysfunction in familial hemiplegic migraine with prolonged aura. ( 20236346 )
2010
186
Cognitive functions, emotional behavior, and quality of life in familial hemiplegic migraine. ( 20535059 )
2010
187
Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice. ( 20631222 )
2010
188
Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain. ( 20735819 )
2010
189
Familial hemiplegic migraine. ( 20816023 )
2010
190
Sporadic hemiplegic migraine and delayed cerebral oedema after minor head trauma: a novel de novo CACNA1A gene mutation. ( 19811514 )
2010
191
Neurological picture. Cortical oedema: a link between delusional misidentification syndromes and hemiplegic migraine. ( 20019221 )
2010
192
Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation. ( 20071244 )
2010
193
Cerebral perfusion changes in hemiplegic migraine: illustrated by Tc-99m ECD brain perfusion scan. ( 20479602 )
2010
194
Sporadic hemiplegic migraine in children. ( 20739784 )
2010
195
Sporadic hemiplegic migraine in children: a report of two new cases. ( 20739815 )
2010
196
Pediatric hemiplegic migraine: susceptibility weighted and MR perfusion imaging abnormality. ( 20821201 )
2010
197
De novo mutations in ATP1A2 and CACNA1A are frequent in early-onset sporadic hemiplegic migraine. ( 20837964 )
2010
198
Moyamoya disease presented as a case of hemiplegic migraine. ( 22798438 )
2010
199
[Off-label use of acetazolamide in a patient with familial hemiplegic migraine and concomitant psychotic episodes]. ( 20148382 )
2010
200
Newly characterised 5' and 3' regions of CACNA1A gene harbour mutations associated with Familial Hemiplegic Migraine and Episodic Ataxia. ( 18976783 )
2009
201
Large scale calcium channel gene rearrangements in episodic ataxia and hemiplegic migraine: implications for diagnostic testing. ( 19586927 )
2009
202
Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report. ( 18624711 )
2009
203
FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2. ( 19007941 )
2009
204
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. ( 19104150 )
2009
205
Familial hemiplegic migraine: linkage to chromosome 14q32 in a Spanish kindred. ( 19153782 )
2009
206
First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy. ( 19220312 )
2009
207
Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies. ( 19242091 )
2009
208
Profound encephalopathy with complete recovery in three children with familial hemiplegic migraine. ( 19317760 )
2009
209
Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine. ( 19372756 )
2009
210
Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice. ( 19847904 )
2009
211
Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. ( 19874388 )
2009
212
A note on the digiti quinti sign in hemiplegic migraine. ( 19025551 )
2009
213
The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition. ( 19189122 )
2009
214
Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations. ( 19332696 )
2009
215
A case of atypical sporadic hemiplegic migraine associated with PFO and hypoplasia of vertebro-basilar system. ( 19421707 )
2009
216
A case of Sturge-Weber syndrome with symptomatic hemiplegic migraine: clinical and multimodality imaging data during a prolonged attack. ( 19733861 )
2009
217
Cessation of sporadic hemiplegic migraine attacks after patent foramen ovale closure. ( 19758362 )
2009
218
Migrainous infarction as a complication of sporadic hemiplegic migraine in childhood. ( 19838529 )
2009
219
CACNA1A mutation linking hemiplegic migraine and alternating hemiplegia of childhood. ( 18498393 )
2008
220
Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes. ( 18028456 )
2008
221
A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred. ( 18184292 )
2008
222
Expansion of the phenotypic spectrum of the CACNA1A T666M mutation: a family with familial hemiplegic migraine type 1, cerebellar atrophy and mental retardation. ( 18279427 )
2008
223
Familial hemiplegic migraine type 2 does not share hypersensitivity to nitric oxide with common types of migraine. ( 18294248 )
2008
224
Electroencephalographic changes and seizures in familial hemiplegic migraine patients with the CACNA1A gene S218L mutation. ( 18313928 )
2008
225
Familial hemiplegic migraine type 1 shows no hypersensitivity to nitric oxide. ( 18384418 )
2008
226
Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. ( 18498390 )
2008
227
The S218L familial hemiplegic migraine mutation promotes deinhibition of Ca(v)2.1 calcium channels during direct G-protein regulation. ( 18581134 )
2008
228
Topiramate-associated worsening symptoms in a patient with familial hemiplegic migraine. ( 18603263 )
2008
229
Divergent sodium channel defects in familial hemiplegic migraine. ( 18621678 )
2008
230
Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel. ( 18632931 )
2008
231
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2. ( 18728015 )
2008
232
Calcitonin gene-related peptide does not cause the familial hemiplegic migraine phenotype. ( 18779512 )
2008
233
Intravenous nimodipine worsening prolonged attack of familial hemiplegic migraine. ( 18846413 )
2008
234
Familial hemiplegic migraine. ( 19185185 )
2008
235
Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil. ( 17614229 )
2008
236
Cessation of hemiplegic migraine auras with greater occipital nerve blockade: a comment. ( 18205798 )
2008
237
CACNA1A R1347Q: a frequent recurrent mutation in hemiplegic migraine. ( 18400034 )
2008
238
Hemiplegic migraine associated with interscalene block and general anaesthesia. ( 18477293 )
2008
239
Screen for CACNA1A and ATP1A2 mutations in sporadic hemiplegic migraine patients. ( 18513263 )
2008
240
Genetic analysis of 27 Spanish patients with hemiplegic migraine, basilar-type migraine and childhood periodic syndromes. ( 18644040 )
2008
241
A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures. ( 18644608 )
2008
242
Sporadic hemiplegic migraine: report of a case with clinical and radiological features. ( 18810316 )
2008
243
Prolonged hemiplegic migraine. ( 21063345 )
2008
244
[Familial hemiplegic migraine resulting in recurrent coma]. ( 18380388 )
2008
245
[Familial and sporadic hemiplegic migraine]. ( 18405771 )
2008
246
The genetic spectrum of a population-based sample of familial hemiplegic migraine. ( 17142831 )
2007
247
Establishing the genetic heterogeneity of familial hemiplegic migraine. ( 17235123 )
2007
248
Familial hemiplegic migraine. ( 17395138 )
2007
249
The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online. ( 17397047 )
2007
250
First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine. ( 17473835 )
2007
251
Apnoeic spells following general anaesthesia in a patient with familial hemiplegic migraine. ( 17697227 )
2007
252
Familial hemiplegic migraine: permanent attack-related neurologic deficits. ( 17883529 )
2007
253
Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine. ( 17952365 )
2007
254
Novel mutation confirms seizure locus SCN1A is also familial hemiplegic migraine locus FHM3. ( 18021921 )
2007
255
Presentation of hemiplegic migraine--hemiplegia and hemi-sensory loss following general anaesthesia. ( 17591140 )
2007
256
Cessation of hemiplegic migraine auras with greater occipital nerve blockade. ( 17578545 )
2007
257
Adult-onset hemiplegic migraine with cortical enhancement and oedema. ( 17645764 )
2007
258
Treatment of hemiplegic migraine with triptans. ( 17718700 )
2007
259
Amino acid changes in the amino terminus of the Na,K-adenosine triphosphatase alpha-2 subunit associated to familial and sporadic hemiplegic migraine. ( 17877748 )
2007
260
Case 125: hemiplegic migraine. ( 17940312 )
2007
261
Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine. ( 18056581 )
2007
262
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine. ( 16538223 )
2006
263
Sporadic and familial hemiplegic migraine: diagnosis and treatment. ( 16628531 )
2006
264
Cough-induced hemiplegic migraine with impaired consciousness in cystic fibrosis. ( 16372353 )
2006
265
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. ( 16472342 )
2006
266
Minor head trauma-induced sporadic hemiplegic migraine coma. ( 16638514 )
2006
267
Imaging abnormalities in sporadic hemiplegic migraine on conventional MRI, diffusion and perfusion MRI and MRS. ( 16886937 )
2006
268
Unilateral spatial neglect in a child with hemiplegic migraine. ( 16919072 )
2006
269
Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca2+ channel activity and inhibitory synaptic transmission. ( 15699344 )
2005
270
Familial hemiplegic migraine: more than just a headache. ( 15728276 )
2005
271
1H-MRS alterations in the cerebellum of patients with familial hemiplegic migraine type 1. ( 15728280 )
2005
272
Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma. ( 15743764 )
2005
273
Gating deficiency in a familial hemiplegic migraine type 1 mutant P/Q-type calcium channel. ( 15795222 )
2005
274
Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation. ( 15843000 )
2005
275
Single-fiber EMG in familial hemiplegic migraine. ( 15883351 )
2005
276
Alterations in the alpha2 isoform of Na,K-ATPase associated with familial hemiplegic migraine type 2. ( 16037212 )
2005
277
Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. ( 16054936 )
2005
278
ATP1A2 mutations in 11 families with familial hemiplegic migraine. ( 16088919 )
2005
279
Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family. ( 16178956 )
2005
280
Autopsy case of acute encephalopathy linked to familial hemiplegic migraine with cerebellar atrophy and mental retardation. ( 16193840 )
2005
281
Symptomatic sporadic hemiplegic migraine. ( 16232163 )
2005
282
Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation. ( 15174025 )
2004
283
Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2. ( 15534763 )
2004
284
Familial hemiplegic migraine, neuropsychiatric symptoms, and Erdheim-Chester disease. ( 15447701 )
2004
285
Familial hemiplegic migraine. ( 14748777 )
2004
286
Deciphering migraine mechanisms: clues from familial hemiplegic migraine genotypes. ( 14755732 )
2004
287
Toward a molecular genetic classification of familial hemiplegic migraine. ( 15115644 )
2004
288
A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2. ( 15133718 )
2004
289
Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants. ( 15159495 )
2004
290
Familial hemiplegic migraine: follow-up findings of diffusion-weighted magnetic resonance imaging (MRI), perfusion-MRI and [99mTc] HMPAO-SPECT in a patient with prolonged hemiplegic aura. ( 15196295 )
2004
291
New CACNA1A gene mutation in a case of familial hemiplegic migraine with status epilepticus. ( 15240985 )
2004
292
Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2. ( 15308625 )
2004
293
Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects. ( 15448138 )
2004
294
Childhood epilepsy, familial hemiplegic migraine, cerebellar ataxia, and a new CACNA1A mutation. ( 15452324 )
2004
295
A G301R Na+/K+ -ATPase mutation causes familial hemiplegic migraine type 2 with cerebellar signs. ( 15459825 )
2004
296
Single-fiber EMG in familial hemiplegic migraine. ( 15557518 )
2004
297
Functional effects of Na+,K+-ATPase gene mutations linked to familial hemiplegic migraine. ( 15970628 )
2004
298
A novel R1347Q mutation in the predicted voltage sensor segment of the P/Q-type calcium-channel alpha-subunit in a family with progressive cerebellar ataxia and hemiplegic migraine. ( 15032980 )
2004
299
EEG in hemiplegic migraine. ( 15069274 )
2004
300
Sporadic hemiplegic migraine. ( 15115642 )
2004
301
Sporadic hemiplegic migraine. ( 15566415 )
2004
302
Severe hemiplegic migraine attack precipitated by fentanyl sedation for esophagogastroscopy. ( 15623730 )
2004
303
[From gene to disease; familial hemiplegic migraine as a result of mutations in a sodium-potassium pump gene]. ( 15495990 )
2004
304
The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. ( 12527722 )
2003
305
Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. ( 12539047 )
2003
306
Familial hemiplegic migraine type 2 is linked to 0.9Mb region on chromosome 1q23. ( 12601705 )
2003
307
Serial MRI in a case of familial hemiplegic migraine. ( 12669159 )
2003
308
Absence of known familial hemiplegic migraine (FHM) mutations in the CACNA1A gene in patients with common migraine: implications for genetic testing. ( 12705332 )
2003
309
Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family. ( 12707077 )
2003
310
Familial hemiplegic migraine. ( 12756128 )
2003
311
Expanding the phenotypic spectrum of the CACNA1A gene T666M mutation: a description of 5 families with familial hemiplegic migraine. ( 12756131 )
2003
312
Increased risk of migraine with typical aura in probands with familial hemiplegic migraine and their relatives. ( 12823495 )
2003
313
Second gene identified for familial hemiplegic migraine. ( 12849225 )
2003
314
Pseudomigraine with lymphocytic pleocytosis: a calcium channelopathy? Clinical description of 10 cases and genetic analysis of the familial hemiplegic migraine gene CACNA1A. ( 12940811 )
2003
315
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. ( 12953268 )
2003
316
New discoveries about the second gene for familial hemiplegic migraine, ATP1A2. ( 14636773 )
2003
317
Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil. ( 12525732 )
2003
318
Sporadic hemiplegic migraine: stamp collecting or food for thought? ( 12601089 )
2003
319
Evidence for a separate type of migraine with aura: sporadic hemiplegic migraine. ( 12601098 )
2003
320
Prolonged cortical electrical depression and diffuse vasospasm without ischemia in a case of severe hemiplegic migraine during pregnancy. ( 12864763 )
2003
321
Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil. ( 12963781 )
2003
322
Sporadic hemiplegic migraine is an aetiologically heterogeneous disorder. ( 14616935 )
2003
323
A population-based study of familial hemiplegic migraine suggests revised diagnostic criteria. ( 12023326 )
2002
324
Familial hemiplegic migraine: clinical features and probable linkage to chromosome 1 in an Italian family. ( 12111614 )
2002
325
Magnetic resonance angiogram evidence of vasospasm in familial hemiplegic migraine. ( 12174974 )
2002
326
Familial hemiplegic migraine mutations increase Ca(2+) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons. ( 12235360 )
2002
327
Multimodal functional imaging of prolonged neurological deficits in a patient suffering from familial hemiplegic migraine. ( 12384224 )
2002
328
Japanese cases of familial hemiplegic migraine with cerebellar ataxia carrying a T666M mutation in the CACNA1A gene. ( 11971066 )
2002
329
Wide clinical variability in a family with a CACNA1A T666m mutation: hemiplegic migraine, coma, and progressive ataxia. ( 11814735 )
2002
330
Hemiplegic migraine with prolonged symptoms: case report. ( 11913583 )
2002
331
Mutation analysis of the CACNA1A calcium channel subunit gene in 27 patients with sporadic hemiplegic migraine. ( 12056940 )
2002
332
An epidemiological survey of hemiplegic migraine. ( 12110112 )
2002
333
Prolonged hemiplegic migraine associated with unilateral hyperperfusion on perfusion weighted magnetic resonance imaging. ( 12122185 )
2002
334
Idiopathic intracranial hypertension presenting as hemiplegic migraine. ( 12222727 )
2002
335
Delayed cerebral edema and fatal coma after minor head trauma: role of the CACNA1A calcium channel subunit gene and relationship with familial hemiplegic migraine. ( 11409427 )
2001
336
The clinical spectrum of familial hemiplegic migraine associated with mutations in a neuronal calcium channel. ( 11439943 )
2001
337
Familial hemiplegic migraine and its abortive therapy with intravenous verapamil. ( 11706128 )
2001
338
Familial hemiplegic migraine: a ion channel disorder. ( 11719257 )
2001
339
Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. ( 11735221 )
2001
340
Sporadic hemiplegic migraine and Sturge-Weber syndrome. ( 11251712 )
2001
341
Hemiplegic migraine during pregnancy: unusual magnetic resonance appearance with SPECT scan correlation. ( 11264693 )
2001
342
Hemiplegic migraine--downstream of a single-base change. ( 11439951 )
2001
343
A case of hemiplegic migraine in childhood: transient unilateral hyperperfusion revealed by perfusion MR imaging and MR angiography. ( 11673182 )
2001
344
[Familial hemiplegic migraine]. ( 15775664 )
2001
345
Alternating hemiplegia of childhood: no mutations in the familial hemiplegic migraine CACNA1A gene. ( 11167897 )
2000
346
Three new familial hemiplegic migraine mutants affect P/Q-type Ca(2+) channel kinetics. ( 10734061 )
2000
347
Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine. ( 10891926 )
2000
348
Decreased hemispheric water mobility in hemiplegic migraine related to mutation of CACNA1A gene. ( 10668728 )
2000
349
Motor cortex excitability in patients with migraine with aura and hemiplegic migraine. ( 10817446 )
2000
350
Hemiplegic migraine induced by exertion. ( 10987906 )
2000
351
CACNA1A gene de novo mutation causing hemiplegic migraine, coma, and cerebellar atrophy. ( 11061267 )
2000
352
CACNA1A mutations: hemiplegic migraine, episodic ataxia type 2, and the others. ( 10408526 )
1999
353
Recurrence of the T666M calcium channel CACNA1A gene mutation in familial hemiplegic migraine with progressive cerebellar ataxia. ( 9915947 )
1999
354
Functional consequences of mutations in the human alpha1A calcium channel subunit linked to familial hemiplegic migraine. ( 10024348 )
1999
355
Familial hemiplegic migraine with cerebellar ataxia and paroxysmal psychosis. ( 10202246 )
1999
356
Coincidence of familial hemiplegic migraine and hemicrania continua? A case report. ( 10403071 )
1999
357
Genetic heterogeneity in Italian families with familial hemiplegic migraine. ( 10408532 )
1999
358
A new CACNA1A gene mutation in acetazolamide-responsive familial hemiplegic migraine and ataxia. ( 10408534 )
1999
359
Recurrent episodes of coma: an unusual phenotype of familial hemiplegic migraine with linkage to chromosome 1. ( 10569214 )
1999
360
Familial hemiplegic migraine mutations change alpha1A Ca2+ channel kinetics. ( 9488686 )
1998
361
Familial hemiplegic migraine. ( 9550587 )
1998
362
Familial hemiplegic migraine with irreversible brain damage. ( 9550598 )
1998
363
Variable clinical expression of mutations in the P/Q-type calcium channel gene in familial hemiplegic migraine. Dutch Migraine Genetics Research Group. ( 9566402 )
1998
364
Current status of genetic discoveries in migraine: familial hemiplegic migraine and beyond. ( 9642538 )
1998
365
Interictal cortical excitability to magnetic stimulation in familial hemiplegic migraine. ( 9153495 )
1997
366
Wolff Award 1997. Involvement of a Ca2+ channel gene in familial hemiplegic migraine and migraine with and without aura. Dutch Migraine Genetics Research Group. ( 9329229 )
1997
367
Familial hemiplegic migraine with crossed cerebellar diaschisis and unilateral meningeal enhancement. ( 9385760 )
1997
368
Mapping of a second locus for familial hemiplegic migraine to 1q21-q23 and evidence of further heterogeneity. ( 9403481 )
1997
369
Familial hemiplegic migraine: involvement of a calcium neuronal channel. ( 9436352 )
1997
370
Partial cosegregation of familial hemiplegic migraine and a benign familial infantile epileptic syndrome. ( 9579893 )
1997
371
A new locus for hemiplegic migraine maps to chromosome 1q31. ( 9371899 )
1997
372
A family with hemiplegic migraine and focal seizures. ( 10728190 )
1997
373
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. ( 8898206 )
1996
374
Familial hemiplegic migraine, nystagmus, and cerebellar atrophy. ( 8572654 )
1996
375
Cerebral angiography complications link cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy to familial hemiplegic migraine. ( 8618700 )
1996
376
Families linked and unlinked to chromosome 19 with familial hemiplegic migraine. ( 8734764 )
1996
377
Familial hemiplegic migraine: a clinical comparison of families linked and unlinked to chromosome 19.DMG RG. ( 8734765 )
1996
378
Identification of a key recombinant narrows the CADASIL gene region to 8 cM and argues against allelism of CADASIL and familial hemiplegic migraine. ( 8786108 )
1996
379
Reversible cerebellar perfusion in familial hemiplegic migraine. ( 8918294 )
1996
380
Acetazolamide responsiveness in familial hemiplegic migraine. ( 8957029 )
1996
381
Familial hemiplegic migraine in the west of Scotland: a clinical and genetic study of seven families. ( 8971111 )
1996
382
A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene. Dutch Migraine Genetic Research Group. ( 9043864 )
1996
383
Familial hemiplegic migraine in developmental age: report of two cases. ( 9177612 )
1996
384
Case report: transient unilateral cerebral oedema in hemiplegic migraine: MR imaging and angiography. ( 8549055 )
1996
385
Familial hemiplegic migraine and autosomal dominant arteriopathy with leukoencephalopathy (CADASIL). ( 7486874 )
1995
386
Abnormal brain and muscle energy metabolism shown by 31P-MRS in familial hemiplegic migraine. ( 7608738 )
1995
387
Adult onset familial hemiplegic migraine. ( 7672961 )
1995
388
Monozygotic twins discordant for familial hemiplegic migraine. ( 7783896 )
1995
389
Familial hemiplegic migraine versus migraine with prolonged aura: an uncertain diagnosis in a family report. ( 7824130 )
1995
390
Familial hemiplegic migraine locus on 19p13 is involved in the common forms of migraine with and without aura. ( 8530012 )
1995
391
Common heredity of familial hemiplegic migraine and basilar artery migraine? ( 8706104 )
1995
392
Is familial hemiplegic migraine a hereditary form of basilar migraine? ( 8706110 )
1995
393
Hemiplegic migraine with CSF abnormalities. ( 7635725 )
1995
394
Familial migraine: exclusion of the susceptibility gene from the reported locus of familial hemiplegic migraine on 19p. ( 7851903 )
1994
395
Genetic heterogeneity of familial hemiplegic migraine. ( 7959770 )
1994
396
Genetic heterogeneity of familial hemiplegic migraine. ( 7977376 )
1994
397
Familial hemiplegic migraine in The Netherlands. Dutch Migraine Genetics Research Group. ( 7988094 )
1994
398
Intracellular and plasma magnesium in familial hemiplegic migraine and migraine with and without aura. ( 8200020 )
1994
399
A gene for familial hemiplegic migraine maps to chromosome 19. ( 8220421 )
1993
400
Hemiplegic migraine and moyamoya disease. ( 8322737 )
1993
401
Transcranial Doppler sonography in familial hemiplegic migraine. ( 2036667 )
1991
402
Alternating hemiplegic migraine in childhood. ( 1839547 )
1991
403
Hemiplegic migraine. ( 2391303 )
1990
404
Hemiplegic migraine following third molar extractions under intravenous sedation: report of a case. ( 2913255 )
1989
405
Hemiplegic migraine in pregnancy. ( 3049450 )
1988
406
Hemiplegic migraine in childhood. ( 3186607 )
1988
407
Juvenile alternating hemiplegic migraine. ( 3205381 )
1988
408
Mitral valve prolapse and platelet aggregation in patients with hemiplegic and non-hemiplegic migraine. ( 3591274 )
1987
409
Focal ischaemia caused by instability of cerebrovascular tone during attacks of hemiplegic migraine. A regional cerebral blood flow study. ( 3651801 )
1987
410
A case of hemiplegic migraine treated with flunarizine. ( 3692829 )
1987
411
Familial hemiplegic migraine: a new case. ( 3818262 )
1986
412
Unusual angiographic appearance during attack of hemiplegic migraine. ( 3721866 )
1986
413
Unusual angiographic appearance during an attack of hemiplegic migraine. ( 3781837 )
1986
414
Hemiplegic migraine and progressive hemifacial atrophy. ( 4026238 )
1985
415
Drugs for alternating hemiplegic migraine. ( 6149366 )
1984
416
Delayed onset dystonia following hemiplegic migraine. ( 6490363 )
1984
417
Some clinical aspects of a hemiplegic migraine patient. ( 6545191 )
1984
418
Non-familial hemiplegic migraine responsive to naloxone. ( 6871987 )
1983
419
Episodes of acute confusion or psychosis in familial hemiplegic migraine. ( 7102264 )
1982
420
Hemiplegic migraine in childhood: diagnostic and therapeutic aspects. ( 7131142 )
1982
421
Clinical aspects of familial hemiplegic migraine in two families. ( 7309446 )
1981
422
Familial hemiplegic migraine: EEG and CT scan study of two cases. ( 7316492 )
1981
423
Cerebral hemodynamics in familial hemiplegic migraine. ( 7346179 )
1981
424
Familial hemiplegic migraine--a reappraisal and a long-term follow-up study. ( 15645832 )
1981
425
Hemiplegic migraine. ( 7288457 )
1981
426
Hemiplegic migraine associated with an aseptic meningeal reaction. ( 7387469 )
1980
427
An autosomal dominant syndrome of hemiplegic migraine, nystagmus, and tremor. ( 7436378 )
1980
428
Aphemia with hemiplegic migraine. ( 573416 )
1979
429
Hemiatrophy of the tongue: a rare complication of the hemiplegic migraine. ( 580267 )
1978
430
Respiratory arrest in familial hemiplegic migraine: a clinical and neuropathological study. ( 912273 )
1977
431
Familial hemiplegic migraine. ( 1127995 )
1975
432
Letter: Hemiplegic migraine: cerebrospinal fluid abnormalities. ( 4852803 )
1974
433
Retinal degeneration in hemiplegic migraine. ( 4854144 )
1974
434
Varieties of hemiplegic migraine. ( 4682551 )
1973
435
Hemiplegic migraine associated with menstruation. ( 5564434 )
1971
436
Familial hemiplegic migraine, retinal degeneration, deafness, and nystagmus. ( 5311627 )
1970
437
HEMIPLEGIC MIGRAINE, A CLINICAL STUDY. ( 14252427 )
1965
438
HEMIPLEGIC MIGRAINE. ( 14272688 )
1965
439
Hemiplegic migraine: a case with paroxysmal shoulder-hand syndrome. ( 14475538 )
1962
440
Familial hemiplegic migraine. ( 13854572 )
1960
441
Hemiplegic migraine. ( 13489617 )
1958
442
Familial hemiplegic migraine. ( 13272341 )
1955
443
Familial hemiplegic migraine. ( 13085199 )
1953

Variations for Hemiplegic Migraine

Expression for Hemiplegic Migraine

Search GEO for disease gene expression data for Hemiplegic Migraine.

Pathways for Hemiplegic Migraine

Pathways related to Hemiplegic Migraine according to KEGG:

38 (showing 9, show less)
# Name Kegg Source Accession
1 MAPK signaling pathway hsa04010
2 Calcium signaling pathway hsa04020
3 Cardiac muscle contraction hsa04260
4 Synaptic vesicle cycle hsa04721
5 Glutamatergic synapse hsa04724
6 Cholinergic synapse hsa04725
7 GABAergic synapse hsa04727
8 Dopaminergic synapse hsa04728
9 Long-term depression hsa04730

Pathways related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

(showing 39, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.33 ATP1A2 ATP1A3 ATP1B1 ATP1B2 GNB1 GNG2
2
Show member pathways
12.98 CACNA1A GNAI2 GNB1 GNG2 OPRM1 SCN1A
3
Show member pathways
12.97 CACNA1A GNAI2 GNB1 GNG2 SCN1A SCN5A
4 12.78 GNAI2 GNB1 GNG2 NOTCH3 SLC2A1
5
Show member pathways
12.78 ATP1A2 ATP1A3 ATP1B1 ATP1B2 GNAI2 SCN5A
6
Show member pathways
12.77 ATP1A2 ATP1A3 ATP1B1 ATP1B2 SCN1A SCN5A
7
Show member pathways
12.69 ATP1A2 ATP1A3 ATP1B1 ATP1B2 GNAI2
8
Show member pathways
12.56 ATP1A2 ATP1A3 ATP1B1 ATP1B2 SCN1A SCN5A
9 12.54 CALCA NOTCH3 OPRM1 SCN1A SCN5A
10
Show member pathways
12.51 CACNA1A GNAI2 GNB1 GNG2 OPRM1
11
Show member pathways
12.47 GNAI2 GNB1 GNG2 OPRM1
12
Show member pathways
12.47 ATP1A2 ATP1A3 ATP1B1 ATP1B2
13 12.31 CACNA1A GNAI2 GNB1 GNG2
14
Show member pathways
12.3 CACNA1A GNAI2 GNB1 GNG2 SLC2A1
15 12.23 ATP1A2 ATP1A3 ATP1B1 ATP1B2 GNAI2
16
Show member pathways
12.16 GNAI2 GNB1 GNG2 SLC2A1
17
Show member pathways
12.09 ATP1A2 ATP1A3 ATP1B1 ATP1B2 GNAI2
18 12.07 CALCA GNAI2 GNB1 GNG2
19 12.03 GNAI2 GNB1 GNG2 NOTCH3
20
Show member pathways
11.99 GNAI2 GNB1 GNG2
21
Show member pathways
11.99 ATP1B1 ATP1B2 CACNA1A CALCA GNAI2 GNB1
22
Show member pathways
11.97 ATP1A2 ATP1A3 ATP1B1 ATP1B2
23 11.92 CACNA1A GNAI2 GNB1 GNG2
24 11.84 ATP1A2 ATP1A3 ATP1B1 ATP1B2
25 11.72 ATP1A2 ATP1A3 ATP1B1 ATP1B2
26 11.66 GNAI2 GNB1 GNG2
27 11.64 GNAI2 GNB1 GNG2
28 11.47 ATP1A2 ATP1A3 ATP1B1 ATP1B2
29 11.45 GNAI2 GNB1 GNG2
30 11.42 ATP1A2 ATP1A3 ATP1B1 ATP1B2
31 11.41 ATP1A2 ATP1A3 ATP1B1 ATP1B2 SLC2A1
32 11.35 CACNA1A GNAI2 GNB1 GNG2
33 11.35 ATP1A2 ATP1A3 ATP1B1 ATP1B2
34 11.29 GNAI2 GNB1 GNG2
35 11.19 ATP1A2 ATP1A3 ATP1B1 ATP1B2
36 11.16 ATP1A2 ATP1A3 ATP1B1 ATP1B2 NOTCH3 SLC2A1
37 10.93 GNB1 GNG2
38 10.92 ATP1A2 ATP1A3 ATP1B1 ATP1B2
39 10.48 GNB1 GNG2

GO Terms for Hemiplegic Migraine

Cellular components related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

(showing 11, show less)
# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.77 ATP1A3 OPRM1 PRRT2 SCN1A SCN5A
2 Z disc GO:0030018 9.67 SCN1A SCN5A SLC2A1
3 sarcolemma GO:0042383 9.65 ATP1A2 ATP1B1 OPRM1 SCN5A SLC2A1
4 T-tubule GO:0030315 9.63 ATP1A2 SCN1A SCN5A
5 caveola GO:0005901 9.62 ATP1A2 ATP1B1 SCN5A SLC2A1
6 heterotrimeric G-protein complex GO:0005834 9.61 GNAI2 GNB1 GNG2
7 extracellular vesicle GO:1903561 9.55 ATP1A2 ATP1A3 ATP1B1 GNAI2 GNB1
8 voltage-gated sodium channel complex GO:0001518 9.48 SCN1A SCN5A
9 intercalated disc GO:0014704 9.35 ATP1A2 ATP1B1 SCN1A SCN5A SLC2A1
10 sodium:potassium-exchanging ATPase complex GO:0005890 8.92 ATP1A2 ATP1A3 ATP1B1 ATP1B2
11 plasma membrane GO:0005886 10.25 ATP1A2 ATP1A3 ATP1B1 ATP1B2 CACNA1A GNAI2

Biological processes related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

(showing 29, show less)
# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.8 ATP1A2 ATP1A3 ATP1B1 ATP1B2
2 sodium ion transport GO:0006814 9.8 ATP1A2 ATP1A3 ATP1B1 ATP1B2 SCN1A SCN5A
3 cardiac muscle contraction GO:0060048 9.71 ATP1A2 ATP1B1 SCN5A
4 potassium ion import across plasma membrane GO:1990573 9.71 ATP1A2 ATP1A3 ATP1B1 ATP1B2
5 cellular sodium ion homeostasis GO:0006883 9.67 ATP1A2 ATP1A3 ATP1B1 ATP1B2
6 membrane depolarization GO:0051899 9.64 CACNA1A SCN5A
7 cellular response to prostaglandin E stimulus GO:0071380 9.63 GNB1 GNG2
8 membrane repolarization GO:0086009 9.63 ATP1A2 ATP1B1 ATP1B2
9 cardiac muscle cell action potential involved in contraction GO:0086002 9.62 SCN1A SCN5A
10 membrane depolarization during action potential GO:0086010 9.62 SCN1A SCN5A
11 G protein-coupled acetylcholine receptor signaling pathway GO:0007213 9.61 GNAI2 GNB1
12 cellular response to steroid hormone stimulus GO:0071383 9.61 ATP1A2 ATP1A3
13 adenylate cyclase-activating dopamine receptor signaling pathway GO:0007191 9.61 GNB1 GNG2 OPRM1
14 neuromuscular process controlling posture GO:0050884 9.6 PRRT2 SCN1A
15 regulation of cardiac muscle cell contraction GO:0086004 9.59 ATP1A2 SCN5A
16 membrane depolarization during cardiac muscle cell action potential GO:0086012 9.58 ATP1A2 SCN5A
17 relaxation of cardiac muscle GO:0055119 9.58 ATP1A2 ATP1B1
18 cellular response to catecholamine stimulus GO:0071870 9.57 GNB1 GNG2
19 positive regulation of potassium ion import GO:1903288 9.56 ATP1B1 ATP1B2
20 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.56 ATP1A2 ATP1A3 ATP1B1 ATP1B2
21 positive regulation of potassium ion transmembrane transporter activity GO:1901018 9.55 ATP1B1 ATP1B2
22 positive regulation of sodium ion export across plasma membrane GO:1903278 9.52 ATP1B1 ATP1B2
23 response to glycoside GO:1903416 9.51 ATP1A2 ATP1A3
24 cell communication by electrical coupling involved in cardiac conduction GO:0086064 9.46 ATP1A2 ATP1A3 ATP1B1 ATP1B2
25 response to pain GO:0048265 9.34 CACNA1A
26 negative regulation of adenylate cyclase activity GO:0007194 9.33 GNAI2
27 cellular potassium ion homeostasis GO:0030007 9.26 ATP1A2 ATP1A3 ATP1B1 ATP1B2
28 sodium ion export across plasma membrane GO:0036376 8.92 ATP1A2 ATP1A3 ATP1B1 ATP1B2
29 ion transport GO:0006811 10.02 ATP1A2 ATP1A3 ATP1B1 ATP1B2 CACNA1A SCN1A

Molecular functions related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

(showing 7, show less)
# Name GO ID Score Top Affiliating Genes
1 voltage-gated ion channel activity GO:0005244 9.58 CACNA1A SCN1A SCN5A
2 voltage-gated sodium channel activity GO:0005248 9.37 SCN1A SCN5A
3 G-protein beta-subunit binding GO:0031681 9.32 GNG2 OPRM1
4 potassium ion binding GO:0030955 9.26 ATP1A2 ATP1B1
5 sodium ion binding GO:0031402 9.16 ATP1A2 ATP1B1
6 steroid hormone binding GO:1990239 8.96 ATP1A2 ATP1A3
7 sodium:potassium-exchanging ATPase activity GO:0005391 8.92 ATP1A2 ATP1A3 ATP1B1 ATP1B2

Sources for Hemiplegic Migraine

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....