MCID: HMP006
MIFTS: 45

Hemiplegic Migraine

Categories: Eye diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Hemiplegic Migraine

MalaCards integrated aliases for Hemiplegic Migraine:

Name: Hemiplegic Migraine 53 37 72
Migraine Hemiplegic 55

Classifications:



External Ids:

KEGG 37 H00775
UMLS 72 C0270862

Summaries for Hemiplegic Migraine

NIH Rare Diseases : 53 Hemiplegic migraine (HM) is a rare type of migraine with aura that occurs with motor weakness during the aura. There are two types of HM which are distinguished based on the family history: familial hemiplegic migraine (FHM, in which at least one other family member has the condition) and sporadic hemiplegic migraine (SHM, in which there is no family history). Signs and symptoms vary but may include visual disturbances, sensory loss, difficulty with speech, weakness on one side of the body, confusion, and impaired consciousness. Severe attacks may occur in both types with prolonged hemiplegia, coma, fever and/or seizures. FHM may be caused by a mutation in any of several genes and is inherited in an autosomal dominant manner.

MalaCards based summary : Hemiplegic Migraine, also known as migraine hemiplegic, is related to sporadic hemiplegic migraine and familial or sporadic hemiplegic migraine. An important gene associated with Hemiplegic Migraine is ATP1A2 (ATPase Na+/K+ Transporting Subunit Alpha 2), and among its related pathways/superpathways are MAPK signaling pathway and Calcium signaling pathway. The drugs Topiramate and Hypoglycemic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and testes, and related phenotypes are Increased viability with SS1P at EC90 and behavior/neurological

KEGG : 37
Sporadic and familial hemiplegic migraines (SHM and FHM) are rare paroxysmal disorders characterized by motor aura and headache. The distinction is based on whether at least one first or second degree relative is also affected, otherwise the diagnostic criteria are similar. The majority of FHM families have a mutation in one of the ion channels CACNA1A, ATP1A2 and SCN1A. SHM is sometimes caused by a de novo mutation in one of the genes. However, at least a quarter of the large families affected and most sporadic cases do not have a mutation in the three genes known to be implicated in this disorder, suggesting that other genes are still to be identified.

Related Diseases for Hemiplegic Migraine

Diseases in the Hemiplegic Migraine family:

Migraine, Familial Hemiplegic, 1 Migraine, Familial Hemiplegic, 2
Migraine, Familial Hemiplegic, 3 Familial Hemiplegic Migraine
Sporadic Hemiplegic Migraine Familial or Sporadic Hemiplegic Migraine

Diseases related to Hemiplegic Migraine via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 165, show less)
# Related Disease Score Top Affiliating Genes
1 sporadic hemiplegic migraine 35.2 SCN1A CACNA1A ATP1A2
2 familial or sporadic hemiplegic migraine 34.3 SCN1A PRRT2 CACNA1A ATP1A2
3 migraine with or without aura 1 32.7 SCN1A PRRT2 NOTCH3 CALCA CACNA1A ATP1A2
4 familial hemiplegic migraine 32.5 SCN5A SCN1A PRKCSH OPRM1 NOTCH3 CALCA
5 headache 31.8 SCN1A CACNA1A ATP1A2
6 migraine without aura 31.6 SCN1A CACNA1A ATP1A2
7 migraine with aura 31.5 SCN1A PRRT2 NOTCH3 CACNA1A ATP1A2
8 episodic ataxia 31.5 PRRT2 CACNA1A ATP1A2
9 aceruloplasminemia 31.0 SLC2A1 CACNA1A ATP1A3
10 hemiplegia 30.7 SLC2A1 SCN1A CALCA CACNA1A ATP1A3 ATP1A2
11 torticollis 30.3 PRRT2 CACNA1A
12 paroxysmal choreoathetosis 30.2 SLC2A1 PRRT2
13 visual epilepsy 30.2 SLC2A1 SCN1A PRRT2 GNB1 ATP1A3
14 alternating hemiplegia of childhood 30.2 SLC2A1 CALCA CACNA1A ATP1A3 ATP1A2
15 dystonia 30.1 SLC2A1 PRRT2 GNB1 ATP1A3
16 epilepsy 30.0 SLC2A1 SCN1A PRRT2 CACNA1A ATP1A3 ATP1A2
17 focal epilepsy 29.9 SLC2A1 SCN1A LOC102724058
18 migraine, familial hemiplegic, 1 12.6
19 migraine, familial hemiplegic, 2 12.6
20 migraine, familial hemiplegic, 3 12.6
21 alternating hemiplegia of childhood 1 11.9
22 convulsions, familial infantile, with paroxysmal choreoathetosis 11.7
23 idiopathic hemiconvulsion-hemiplegia syndrome 11.5
24 alternating hemiplegia of childhood 2 11.4
25 phosphoglycerate kinase deficiency 11.4
26 ataxia and polyneuropathy, adult-onset 10.9
27 ocular motor apraxia 10.7
28 aphasia 10.6
29 episodic ataxia, type 2 10.6
30 pathologic nystagmus 10.6
31 spinocerebellar ataxia 6 10.5
32 seizure disorder 10.5
33 generalized epilepsy with febrile seizures plus, type 2 10.5 SCN1A LOC102724058
34 generalized epilepsy with febrile seizures plus, type 1 10.5 SCN1A LOC102724058
35 encephalopathy 10.5
36 autosomal dominant cerebellar ataxia 10.5
37 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 10.4
38 hydrops, lactic acidosis, and sideroblastic anemia 10.4
39 atp1a3-related neurologic disorders 10.4
40 febrile seizures 10.4
41 yemenite deaf-blind hypopigmentation syndrome 10.3
42 benign familial infantile epilepsy 10.3
43 brain edema 10.3
44 specific language disorder 10.3
45 episodic kinesigenic dyskinesia 1 10.3
46 patent foramen ovale 10.3
47 sturge-weber syndrome 10.2
48 moyamoya disease 1 10.2
49 stroke, ischemic 10.2
50 seizures, benign familial infantile, 2 10.2
51 status epilepticus 10.2
52 cerebrovascular disease 10.2
53 retinal degeneration 10.2
54 weber syndrome 10.2
55 depression 10.2
56 paroxysmal dyskinesia 10.2
57 glut1 deficiency syndrome 2 10.2 SLC2A1 PRRT2
58 cluster headache 10.2 CALCA CACNA1A
59 cystic fibrosis 10.1
60 branchiootic syndrome 1 10.1
61 migraine with or without aura 6 10.1
62 generalized epilepsy with febrile seizures plus 10.1
63 allergic hypersensitivity disease 10.1
64 pseudobulbar palsy 10.1
65 calcinosis 10.1
66 childhood absence epilepsy 10.1
67 transient cerebral ischemia 10.1
68 speech disorder 10.1
69 47,xyy 10.1
70 48,xyyy 10.1
71 cerebellar degeneration 10.1
72 migraine with brainstem aura 10.1
73 genetic epilepsy with febrile seizures plus 10.1
74 head injury 10.1
75 myoclonus 10.1
76 tremor 10.1
77 infantile epilepsy syndrome 10.1
78 dystonia, dopa-responsive 10.1 SLC2A1 PRRT2 ATP1A3
79 early onset absence epilepsy 10.0 SLC2A1 PRRT2
80 neurofibromatosis, type ii 10.0
81 epilepsy, benign occipital 10.0
82 fibrosis of extraocular muscles, congenital, 1 10.0
83 systemic lupus erythematosus 10.0
84 episodic ataxia, type 1 10.0
85 obsessive-compulsive disorder 10.0
86 pulmonary hypertension, primary, 1 10.0
87 strabismus 10.0
88 3-methylglutaconic aciduria, type iii 10.0
89 pulmonary arteriovenous fistulas 10.0
90 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 10.0
91 cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss 10.0
92 orthostatic intolerance 10.0
93 langerhans cell histiocytosis 10.0
94 migraine with or without aura 5 10.0
95 myocardial infarction 10.0
96 chorea, childhood-onset, with psychomotor retardation 10.0
97 angina pectoris 10.0
98 exanthem 10.0
99 focal dystonia 10.0
100 focal hand dystonia 10.0
101 crest syndrome 10.0
102 sensorineural hearing loss 10.0
103 monocular esotropia 10.0
104 viral meningitis 10.0
105 amnestic disorder 10.0
106 pertussis 10.0
107 disseminated intravascular coagulation 10.0
108 arteriovenous malformation 10.0
109 coronary artery vasospasm 10.0
110 dyscalculia 10.0
111 locked-in syndrome 10.0
112 telangiectasis 10.0
113 quadriplegia 10.0
114 choreatic disease 10.0
115 facial paralysis 10.0
116 conversion disorder 10.0
117 vascular disease 10.0
118 mood disorder 10.0
119 histiocytosis 10.0
120 lactic acidosis 10.0
121 hair disease 10.0
122 myopathy 10.0
123 erdheim-chester disease 10.0
124 non-langerhans-cell histiocytosis 10.0
125 intracranial embolism 10.0
126 movement disease 10.0
127 essential tremor 10.0
128 mitochondrial myopathy 10.0
129 lupus erythematosus 10.0
130 mechanical strabismus 10.0
131 scotoma 10.0
132 intracranial hypertension 10.0
133 encephalitis 10.0
134 esotropia 10.0
135 mitochondrial disorders 10.0
136 prrt2-associated paroxysmal movement disorders 10.0
137 scn1a seizure disorders 10.0
138 athetosis 10.0
139 cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorinural hearing loss 10.0
140 hemicrania continua 10.0
141 mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes 10.0
142 pulmonary arteriovenous malformation 10.0
143 short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms 10.0
144 spastic paraparesis 10.0
145 raynaud phenomenon 10.0
146 anoxia 10.0
147 brain injury 10.0
148 cerebral atrophy 10.0
149 cerebral hypoxia 10.0
150 chronic pain 10.0
151 dementia - subcortical 10.0
152 paresthesia 10.0
153 persistent vegetative state 10.0
154 spasticity 10.0
155 spinal cord infarction 10.0
156 spinocerebellar atrophy 10.0
157 syncope 10.0
158 traumatic brain injury 10.0
159 whiplash 10.0
160 benign paroxysmal torticollis of infancy 10.0
161 atrial septal aneurysm 10.0
162 rare movement disorder 10.0
163 thyrotoxic periodic paralysis 10.0 ATP1B2 ATP1B1 ATP1A2
164 alacrima, achalasia, and mental retardation syndrome 9.8 SLC2A1 SCN1A GNB1 CACNA1A
165 epilepsy, idiopathic generalized 9.8 SLC2A1 SCN1A OPRM1 CACNA1A

Graphical network of the top 20 diseases related to Hemiplegic Migraine:



Diseases related to Hemiplegic Migraine

Symptoms & Phenotypes for Hemiplegic Migraine

GenomeRNAi Phenotypes related to Hemiplegic Migraine according to GeneCards Suite gene sharing:

26 (showing 1, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability with SS1P at EC90 GR00376-A-1 8.8 ATP1A3 GNAI2 GNB1

MGI Mouse Phenotypes related to Hemiplegic Migraine:

46 (showing 5, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.1 ATP1A2 ATP1A3 ATP1B2 CACNA1A GNAI2 GNB1
2 mortality/aging MP:0010768 10.07 ATP1A2 ATP1A3 ATP1B1 ATP1B2 CACNA1A GNAI2
3 nervous system MP:0003631 9.93 ATP1A2 ATP1A3 ATP1B2 CACNA1A GNAI2 GNB1
4 normal MP:0002873 9.56 ATP1A2 ATP1B1 CACNA1A GNAI2 NOTCH3 OPRM1
5 respiratory system MP:0005388 9.23 ATP1A2 ATP1A3 ATP1B1 CACNA1A GNAI2 GNB1

Drugs & Therapeutics for Hemiplegic Migraine

Drugs for Hemiplegic Migraine (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 16, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 2, Phase 3 97240-79-4 5284627
2 Hypoglycemic Agents Phase 2, Phase 3
3
Ethosuximide Approved Phase 1, Phase 2 77-67-8 3291
4 Anticonvulsants Phase 1, Phase 2
5
Nitroglycerin Approved, Investigational 55-63-0 4510
6
Salmon Calcitonin Approved, Investigational 47931-85-1 16129616
7
Pancrelipase Approved, Investigational 53608-75-6
8
Calcium Approved, Nutraceutical 7440-70-2 271
9
Calcitonin gene-related peptide Investigational 83652-28-2
10 Vasodilator Agents
11 Hormones
12 Katacalcin
13 Calcium, Dietary
14 calcitonin
15 Bone Density Conservation Agents
16 pancreatin

Interventional clinical trials:

(showing 10, show less)
# Name Status NCT ID Phase Drugs
1 A Double-Blind Dose Comparison Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine Completed NCT00131443 Phase 2, Phase 3 Topiramate
2 Pharmacologic and Genetic Evaluation of a C. Elegans Model for Migraine Terminated NCT01122381 Phase 1, Phase 2 ethosuximide
3 Identification of Inflammatory Markers in Migraine Patients Unknown status NCT00969995
4 Inflammatory Markers Identification in Migraine Patients Unknown status NCT01618201
5 Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2 Completed NCT00257985 GTN
6 Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2. Completed NCT00358839 CGRP
7 Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Completed NCT00541736 Nitroglycerine
8 CGRP-induced Headache in Patients With Familial Hemiplegic Migraine, Migraine With Aura and Healthy Controls Completed NCT00687947 CGRP
9 CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load Completed NCT01924052 CGRP
10 Genetic Analysis of Children With Cyclic Vomiting Syndrome and Migraines Recruiting NCT00727974

Search NIH Clinical Center for Hemiplegic Migraine

Genetic Tests for Hemiplegic Migraine

Anatomical Context for Hemiplegic Migraine

MalaCards organs/tissues related to Hemiplegic Migraine:

41
Brain, Bone, Testes, Trigeminal Ganglion, Spinal Cord, Cortex, Cerebellum

Publications for Hemiplegic Migraine

Articles related to Hemiplegic Migraine:

(showing 982, show less)
# Title Authors PMID Year
1
Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation. 9 38
20071244 2010
2
Sporadic hemiplegic migraine and delayed cerebral oedema after minor head trauma: a novel de novo CACNA1A gene mutation. 9 38
19811514 2010
3
Large scale calcium channel gene rearrangements in episodic ataxia and hemiplegic migraine: implications for diagnostic testing. 9 38
19586927 2009
4
The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition. 9 38
19189122 2009
5
The interplay of two single nucleotide polymorphisms in the CACNA1A gene may contribute to migraine susceptibility. 9 38
19429006 2009
6
Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations. 9 38
19332696 2009
7
A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures. 9 38
18644608 2008
8
Screen for CACNA1A and ATP1A2 mutations in sporadic hemiplegic migraine patients. 9 38
18513263 2008
9
CACNA1A mutation linking hemiplegic migraine and alternating hemiplegia of childhood. 9 38
18498393 2008
10
Genetics of migraine: an update with special attention to genetic comorbidity. 9 38
18451712 2008
11
ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses. 9 38
18483709 2008
12
A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred. 9 38
18184292 2008
13
Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes. 9 38
18028456 2008
14
Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine. 9 38
18056581 2007
15
Amino acid changes in the amino terminus of the Na,K-adenosine triphosphatase alpha-2 subunit associated to familial and sporadic hemiplegic migraine. 9 38
17877748 2007
16
First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine. 9 38
17473835 2007
17
Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures. 9 38
16116111 2005
18
No mutations in CACNA1A and ATP1A2 in probands with common types of migraine. 9 38
15210532 2004
19
Update on the genetics of migraine. 9 38
14624354 2004
20
Wide clinical variability in a family with a CACNA1A T666m mutation: hemiplegic migraine, coma, and progressive ataxia. 9 38
11814735 2002
21
The clinical spectrum of familial hemiplegic migraine associated with mutations in a neuronal calcium channel. 9 38
11439943 2001
22
Familial dyskinesia and facial myokymia (FDFM): a novel movement disorder. 9 38
11310626 2001
23
CACNA1A gene de novo mutation causing hemiplegic migraine, coma, and cerebellar atrophy. 9 38
11061267 2000
24
[Genetics of migraine]. 9 38
11072644 2000
25
Hemiplegic migraine induced by exertion. 9 38
10987906 2000
26
Decreased hemispheric water mobility in hemiplegic migraine related to mutation of CACNA1A gene. 9 38
10668728 2000
27
CACNA1A mutations: hemiplegic migraine, episodic ataxia type 2, and the others. 9 38
10408526 1999
28
Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions. 38
30922082 2019
29
Smooth muscle Ca2+ sensitization causes hypercontractility of middle cerebral arteries in mice bearing the familial hemiplegic migraine type 2 associated mutation. 38
29513112 2019
30
Phase Contrast MRI Suggests an Internal Carotid Vascular Tone Alteration in Migraines. 38
31170735 2019
31
To tPA or Not to tPA: Two Medical-Legal Misadventures of Diagnosing a Cerebrovascular Accident as a Stroke Mimic. 38
31404351 2019
32
Teaching NeuroImages: Neuroimaging in hemiplegic migraine. 38
31383811 2019
33
Genetic mouse models of migraine. 38
31299902 2019
34
Prolonged Postictal Coma in Hemiplegic Migraine: A Case Report. 38
31339554 2019
35
White Matter Hyperintensities in Patients with Sporadic Hemiplegic Migraine. 38
31304994 2019
36
Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans. 38
31364988 2019
37
Relief Following Chronic Stress Augments Spreading Depolarization Susceptibility in Familial Hemiplegic Migraine Mice. 38
31299346 2019
38
Basal astrocyte and microglia activation in the central nervous system of Familial Hemiplegic Migraine Type I mice. 38
31260335 2019
39
Involvement of the Na+ ,K+ -ATPase isoforms in control of cerebral perfusion. 38
30768809 2019
40
Getting to the Heart of the Matter: Migraine, Triptans, DHE, Ditans, CGRP Antibodies, First/Second-Generation Gepants, and Cardiovascular Risk. 38
31318457 2019
41
Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine. 38
31331109 2019
42
Major intra-familial phenotypic heterogeneity and incomplete penetrance due to a CACNA1A pathogenic variant. 38
30142438 2019
43
Advances in genetics of migraine. 38
31226929 2019
44
Advance in genetics of migraine. 38
30883436 2019
45
Mouse Models of Familial Hemiplegic Migraine for Studying Migraine Pathophysiology. 38
31092180 2019
46
Aura and Stroke: relationship and what we have learnt from preclinical models. 38
31142262 2019
47
A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2. 38
31053037 2019
48
Cognitive impairment in children with CACNA1A mutations. 38
31115040 2019
49
Caffeine does not affect susceptibility to cortical spreading depolarization in mice. 38
29651899 2019
50
Gain of function of sporadic/familial hemiplegic migraine-causing SCN1A mutations: Use of an optimized cDNA. 38
29986598 2019
51
Trigeminovascular calcitonin gene-related peptide function in Cacna1a R192Q-mutated knock-in mice. 38
28792272 2019
52
Clinical neurophysiology of migraine with aura. 38
31035929 2019
53
Familial hemiplegic migraine in a child with seizure disorder: clinical history is the key to diagnosis. 38
30914414 2019
54
Sporadic Hemiplegic Migraine with Psychotic Episode and MRI Abnormalities - Therapeutic Dilemma: a Case Report. 38
30948700 2019
55
A Retrospective, Epidemiological Review of Hemiplegic Migraines in a Military Population. 38
30877794 2019
56
Postoperative hemiparesis following tonsillectomy. 38
30788090 2019
57
Migrainous Infarction in a Patient With Sporadic Hemiplegic Migraine and Cystic Fibrosis: A 99mTc-HMPAO Brain SPECT Study. 38
30620050 2019
58
Neuronal injuries evidenced by transient cortical magnetic resonance enhancement in hemiplegic migraine: A case report. 38
30092648 2019
59
Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes. 38
30819023 2019
60
Acute-Onset Ataxia and Transient Cerebellar Diffusion Restriction Associated with a PRRT2 Mutation. 38
30501978 2019
61
The neuropsychiatric phenotype in CACNA1A mutations: a retrospective single center study and review of the literature. 38
30063100 2019
62
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations. 38
30690204 2019
63
The Effect of Onabotulinum Toxin on Aura Frequency and Severity in Patients With Hemiplegic Migraine - A Comment. 38
30575970 2019
64
Benign paroxysmal torticollis of infancy does not lead to neurological sequelae. 38
29956301 2018
65
A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms. 38
30423015 2018
66
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2. 38
30446731 2018
67
Ultrastructural changes in microvessels in familial hemiplegic migraine with CACNA1A mutation. 38
30148448 2018
68
What Are We Missing in the Diagnostic Criteria for Migraine? 38
30291572 2018
69
Episodic Migraine With and Without Aura: Key Differences and Implications for Pathophysiology, Management, and Assessing Risks. 38
30291554 2018
70
The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families. 38
29486580 2018
71
Acute Hemiplegia in Children: A Prospective Study of Etiology, Clinical Presentation, and Outcome from Western India. 38
30271041 2018
72
Time Course of Cerebral Perfusion Changes in Children with Migraine with Aura Mimicking Stroke. 38
29903927 2018
73
Multimodal imaging findings during severe attacks of familial hemiplegic migraine type 2. 38
30097147 2018
74
Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway. 38
30080864 2018
75
New CACNA1A deletions are associated to migraine phenotypes. 38
30167989 2018
76
Enhanced susceptibility to cortical spreading depression in two types of Na+,K+-ATPase α2 subunit-deficient mice as a model of familial hemiplegic migraine 2. 38
29041816 2018
77
Transcriptomic profiling of trigeminal nucleus caudalis and spinal cord dorsal horn. 38
29723522 2018
78
The Effect of OnabotulinumtoxinA on Aura Frequency and Severity in Patients With Hemiplegic Migraine: Case Series of 11 Patients. 38
29762872 2018
79
Two novel families with hemiplegic migraine caused by recurrent SCN1A mutation p.F1499L. 38
29145747 2018
80
Pediatric sporadic hemiplegic migraine (ATP1A2 gene): a case report and brief literature review. 38
29904856 2018
81
Flunarizine in migraine-related headache prevention: results from 200 patients treated in the UK. 38
29512871 2018
82
Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families. 38
29731251 2018
83
Ten years of follow-up in a large family with familial hemiplegic migraine type 1: Clinical course and implications for treatment. 38
28856914 2018
84
Whole-exome sequencing for variant discovery in blepharospasm. 38
29770609 2018
85
Transient regional cerebral hypoperfusion during a paroxysmal hemiplegic event in GLUT1 deficiency syndrome. 38
29500071 2018
86
Hemiplegic Migraine as the Initial Presentation of Biopsy Positive Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy. 38
30027023 2018
87
Brain atrophy following hemiplegic migraine attacks. 38
28750589 2018
88
Hemiplegic migraine and stroke in Mary Shelley. 38
29553379 2018
89
Clinical Benefit of NMDA Receptor Antagonists in a Patient With ATP1A2 Gene Mutation. 38
29610157 2018
90
Glutamate and Its Receptors as Therapeutic Targets for Migraine. 38
29508147 2018
91
Mild Traumatic Brain Injury in a High School Football Player With Familial Hemiplegic Migraine: A Case Report. 38
28918117 2018
92
An Atypical Rett Syndrome Phenotype Due to a Novel Missense Mutation in CACNA1A. 38
29366381 2018
93
Reversible cortical thickening in hemiplegic migraine. 38
28120619 2018
94
Somatic sprouts of the Purkinje cells in a patient with multiple system atrophy. 38
29575082 2018
95
Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications. 38
28058944 2018
96
Pathophysiological mechanisms of migraine and epilepsy: Similarities and differences. 38
29129678 2018
97
Stroke-Like Episodes and Cerebellar Syndrome in Phosphomannomutase Deficiency (PMM2-CDG): Evidence for Hypoglycosylation-Driven Channelopathy. 38
29470411 2018
98
Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation. 38
29343472 2018
99
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series. 38
28445178 2018
100
Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine. 38
30038559 2018
101
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report. 38
29867740 2018
102
Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report. 38
30498473 2018
103
Ocular Dipping in a Patient With Hemiplegic Migraine. 38
29384561 2018
104
PRRT2-Associated Paroxysmal Movement Disorders 38
29334453 2018
105
Erratum to: De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. 38
28702766 2017
106
De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report. 38
28593511 2017
107
Sulcal hyperintensity mimicking subarachnoid hemorrhage in the context of hemiplegic migraine. 38
29236896 2017
108
In situ imaging reveals properties of purinergic signalling in trigeminal sensory ganglia in vitro. 38
28822016 2017
109
Disruption of Ankyrin B and Caveolin-1 Interaction Sites Alters Na+,K+-ATPase Membrane Diffusion. 38
28988699 2017
110
A novel SCN1A mutation identified in a Chinese family with familial hemiplegic migraine: A case report. 38
27919014 2017
111
The α2β2 isoform combination dominates the astrocytic Na+ /K+ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation. 38
28787093 2017
112
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. 38
28811059 2017
113
[PRRT2 mutation and infantile convulsions]. 38
28870817 2017
114
Combined early treatment in hemiplegic attacks related to CACNA1A encephalopathy with brain oedema: Blocking the cascade? 38
27651281 2017
115
[Childhood sporadic type of hemiplegic migraine with arteria cerebri media hypoperfusion]. 38
29870626 2017
116
First Episode of Hemiplegic Migraine. 38
28601240 2017
117
Possible Involvement of the CACNA1E Gene in Migraine: A Search for Single Nucleotide Polymorphism in Different Clinical Phenotypes. 38
28573794 2017
118
Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation. 38
27226003 2017
119
Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy. 38
28566180 2017
120
Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation. 38
28430869 2017
121
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. 38
28637637 2017
122
EEG findings during "paroxysmal hemiplegia" in a patient with GLUT1-deficiency. 38
28129950 2017
123
Missense mutations of CACNA1A are a frequent cause of autosomal dominant nonprogressive congenital ataxia. 38
28007337 2017
124
Hyperpolarization-activated current Ih in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1. 38
28363781 2017
125
Reconsideration of the diagnosis and treatment of childhood migraine: A practical review of clinical experiences. 38
27993427 2017
126
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine. 38
27032388 2017
127
Shared mechanisms of epilepsy, migraine and affective disorders. 38
28527083 2017
128
Stroke-like attack: first episode of sporadic hemiplegic migraine. 38
28527090 2017
129
Postoperative Hemiplegic Migraine After a Laparoscopic Cholecystectomy: A Case Report. 38
28045726 2017
130
[Hemiplegic migraine and arterial spin labelling sequence]. 38
27234821 2017
131
Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders. 38
28271496 2017
132
Transcriptomic Changes in Rat Cortex and Brainstem After Cortical Spreading Depression With or Without Pretreatment With Migraine Prophylactic Drugs. 38
27919769 2017
133
Identification of the first in Poland CACNA1A gene mutation in familial hemiplegic migraine. Case report. 38
28169007 2017
134
Cerebellar function and ischemic brain lesions in migraine patients from the general population. 38
27059879 2017
135
In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures. 38
28223480 2017
136
Transient Ischemic Attack and Ischemic Stroke in Danon Disease with Formation of Left Ventricular Apical Thrombus despite Normal Systolic Function. 38
29085695 2017
137
Acute Intravenous Calcium Antagonist for Suspected Hemiplegic Migraine - A Case Story. 38
28559833 2017
138
Cerebellar Atrophy and Changes in Cytokines Associated with the CACNA1A R583Q Mutation in a Russian Familial Hemiplegic Migraine Type 1 Family. 38
28900389 2017
139
Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. 38
28123025 2017
140
The genetic relationship between epilepsy and hemiplegic migraine. 38
28479855 2017
141
Hemiplegic migraine and late-onset photosensitive epileptic seizures. 38
27406575 2016
142
Episodic ataxia and SCA6 within the same family due to the D302N CACNA1A gene mutation. 38
27871455 2016
143
Sporadic hemiplegic migraine and giant tumefactive perivascular space: Is there an association? 38
26696413 2016
144
Characterising the premonitory stage of migraine in children: a clinic-based study of 100 patients in a specialist headache service. 38
27770403 2016
145
Intermittent Theta Slowings in Contralateral Side of Weakness after Sleep Deprivation on Spot EEG in Sporadic Hemiplegic Migraine. 38
28101483 2016
146
Early-onset familial hemiplegic migraine due to a novel SCN1A mutation. 38
26763045 2016
147
Metabolomic changes in CSF of migraine patients measured with 1H-NMR spectroscopy. 38
27734045 2016
148
Clinical and electroencephalographic abnormalities during the full duration of a sporadic hemiplegic migraine attack. 38
27155821 2016
149
Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management. 38
28185542 2016
150
Targeted next generation sequencing identifies novel NOTCH3 gene mutations in CADASIL diagnostics patients. 38
27881154 2016
151
Prevalence of lifetime depression in a large hemiplegic migraine cohort. 38
27807184 2016
152
Acetazolamide in vestibular migraine prophylaxis: a retrospective study. 38
26728486 2016
153
Hemiplegic Migraine Presenting with Prolonged Somnolence: A Case Report. 38
27790126 2016
154
Time course of downbeat positioning nystagmus in familial hemiplegic migraine type 1 treated with acetazolamide. 38
27538634 2016
155
Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1. 38
27346147 2016
156
Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2. 38
27354390 2016
157
Molecular factors in migraine. 38
27191890 2016
158
Activity-dependent calcium, oxygen, and vascular responses in a mouse model of familial hemiplegic migraine type 1. 38
27314908 2016
159
Biallelic CACNA1A mutations cause early onset epileptic encephalopathy with progressive cerebral, cerebellar, and optic nerve atrophy. 38
27250579 2016
160
The Genetics of Benign Paroxysmal Torticollis of Infancy: Is There an Association With Mutations in the CACNA1A Gene? 38
26961263 2016
161
Periodic Lateralized Epileptiform Discharges (PLEDs) in Patients With Neurosyphilis and HIV Infection. 38
25326288 2016
162
Stunned myocardium after an anesthetic procedure in a pediatric patient - case report. 38
27179636 2016
163
Hemiparesis after general anesthesia in a patient with migraine with unilateral motor symptoms. 38
27185697 2016
164
[Missense mutation R1345Q in CACNA1A gene causes a new type of ataxia with episodic tremor: clinical features, genetic analysis and treatment in a familial case]. 38
27435762 2016
165
Eye movement disorders are an early manifestation of CACNA1A mutations in children. 38
26814174 2016
166
Animal models of monogenic migraine. 38
27154999 2016
167
The migraine-stroke connection: A genetic perspective. 38
26660850 2016
168
Involvement of astrocyte and oligodendrocyte gene sets in migraine. 38
26646788 2016
169
A retrospective analysis of triptan and dhe use for basilar and hemiplegic migraine. 38
27062528 2016
170
Expression and function of calcitonin gene-related peptide (CGRP) receptors in trigeminal ganglia of R192Q Cacna1a knock-in mice. 38
27021026 2016
171
Alcohol-induced headaches: Evidence for a central mechanism? 38
27114660 2016
172
Perfusion and pH MRI in familial hemiplegic migraine with prolonged aura. 38
25948653 2016
173
P2C-Type ATPases and Their Regulation. 38
25631710 2016
174
Migraine in the era of precision medicine. 38
27127758 2016
175
Large-Scale Functional RNAi Screen in C. elegans Identifies TGF-β and Notch Signaling Pathways as Modifiers of CACNA1A. 38
27005779 2016
176
Next-generation sequencing identifies novel CACNA1A gene mutations in episodic ataxia type 2. 38
27066515 2016
177
A case report of sporadic hemiplegic migraine associated cerebral hypoperfusion: comparison of arterial spin labeling and dynamic susceptibility contrast perfusion MR imaging. 38
26250760 2016
178
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. 38
26911348 2016
179
ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease. 38
27445835 2016
180
Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine. 38
27175010 2016
181
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation. 38
27818813 2016
182
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. 38
27313535 2016
183
Insights into the Pathology of the α2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models. 38
27199775 2016
184
Managing Brain Extracellular K(+) during Neuronal Activity: The Physiological Role of the Na(+)/K(+)-ATPase Subunit Isoforms. 38
27148079 2016
185
Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes. 38
26747084 2016
186
P068. A suggestive case of hemiplegic migraine: a diagnostic challenge. 38
28132306 2015
187
Cortical spreading depression and familial hemiplegic migraine 2015. 38
28132368 2015
188
The evolving spectrum of PRRT2-associated paroxysmal diseases. 38
26598493 2015
189
The clinical and genetic heterogeneity of paroxysmal dyskinesias. 38
26598494 2015
190
Case Study: Somatic Sprouts and Halo-Like Amorphous Materials of the Purkinje Cells in Huntington's Disease. 38
25962893 2015
191
Near infrared spectroscopy--investigations in neurovascular diseases. 38
26621402 2015
192
P016. Congenital ataxia, hemiplegic migraine due to a novel mutation of CACNA1A: a case report. 38
28132242 2015
193
CAPOS syndrome and hemiplegic migraine in a novel pedigree with the specific ATP1A3 mutation. 38
26453127 2015
194
MRPL44 mutations cause a slowly progressive multisystem disease with childhood-onset hypertrophic cardiomyopathy. 38
25797485 2015
195
Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels. 38
26208839 2015
196
Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice. 38
26032020 2015
197
Unique Migraine Subtypes, Rare Headache Disorders, and Other Disturbances. 38
26252589 2015
198
Field-testing of the ICHD-3 beta/proposed ICD-11 diagnostic criteria for migraine with aura. 38
25424707 2015
199
Familial Hemiplegic Migraine and Recurrent Episodes of Psychosis: A Case Report. 38
26087244 2015
200
Greater Occipital Nerve Blockade: A Safe and Effective Option for the Acute Treatment of Hemiplegic Aura. 38
26140423 2015
201
Concordant occipital and supraorbital neurostimulation therapy for hemiplegic migraine; initial experience; a case series. 38
25688595 2015
202
Large-scale mass spectrometry imaging investigation of consequences of cortical spreading depression in a transgenic mouse model of migraine. 38
25877011 2015
203
Malan syndrome: Sotos-like overgrowth with de novo NFIX sequence variants and deletions in six new patients and a review of the literature. 38
25118028 2015
204
Plasma metabolic profiling after cortical spreading depression in a transgenic mouse model of hemiplegic migraine by capillary electrophoresis--mass spectrometry. 38
25856790 2015
205
Paroxysmal tonic upward gaze as a presentation of de-novo mutations in CACNA1A. 38
25596066 2015
206
From migraine genes to mechanisms. 38
25789438 2015
207
Migraine and epilepsy: review of the literature. 38
25754865 2015
208
Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2. 38
25411546 2015
209
Rescuable folding defective NaV1.1 (SCN1A) mutants in epilepsy: properties, occurrence, and novel rescuing strategy with peptides targeted to the endoplasmic reticulum. 38
25576396 2015
210
Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. 38
25716839 2015
211
Stress hormone corticosterone enhances susceptibility to cortical spreading depression in familial hemiplegic migraine type 1 mutant mice. 38
25447936 2015
212
[Genetic aspects of migraine]. 38
26356526 2015
213
Familial hemiplegic migraine type 1 associated with parkinsonism: a case report. 38
25969684 2015
214
Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects of a single mutation. 38
25762895 2015
215
Novel frameshift mutation in the CACNA1A gene causing a mixed phenotype of episodic ataxia and familiar hemiplegic migraine. 38
25468264 2015
216
Abnormal cortical synaptic transmission in CaV2.1 knockin mice with the S218L missense mutation which causes a severe familial hemiplegic migraine syndrome in humans. 38
25741235 2015
217
Migraine pathophysiology: lessons from mouse models and human genetics. 38
25496898 2015
218
Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice. 38
25424478 2015
219
[Sporadic hemiplegic migraine]. 38
25944138 2015
220
Hemiplegia and headache: a review of hemiplegia in headache disorders. 38
25501955 2015
221
A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx. 38
26716990 2015
222
Familial hemiplegic migraine type-1 mutated cav2.1 calcium channels alter inhibitory and excitatory synaptic transmission in the lateral superior olive of mice. 38
25481823 2015
223
[Phenotypic variability in a family with genetically verified familial hemiplegic migraine type 2]. 38
25612963 2015
224
A novel SLC2A1 mutation linking hemiplegic migraine with alternating hemiplegia of childhood. 38
24824604 2015
225
Genome-wide screen for modifiers of Na (+) /K (+) ATPase alleles identifies critical genetic loci. 38
25476251 2014
226
An altered GABA-A receptor function in spinocerebellar ataxia type 6 and familial hemiplegic migraine type 1 associated with the CACNA1A gene mutation. 38
26675662 2014
227
Two novel SCN1A mutations identified in families with familial hemiplegic migraine. 38
24707016 2014
228
Hemiplegic migraine: An atypical presentation of Moyamoya disease. 38
25538508 2014
229
Familial hemiplegic migraine: a model for the genetic studies of migraine. 38
24707017 2014
230
Biochemical changes in the brain of hemiplegic migraine patients measured with 7 tesla 1H-MRS. 38
24651393 2014
231
Phenotypic variability in a four generation family with a p.Thr666Met CACNA1A gene mutation. 38
25266619 2014
232
Familial hemiplegic migraine due to L263V SCN1A mutation: discordance for epilepsy between two kindreds from Douro Valley. 38
24646837 2014
233
Benefit of carbamazepine in a patient with hemiplegic migraine associated with PRRT2 mutation. 38
24506539 2014
234
Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in CaV2.1 knockin migraine mice. 38
24907493 2014
235
Reversible hemiparesis in a patient with migraine. 38
25166776 2014
236
Familial hemiplegic migraine treated by sodium valproate and lamotrigine. 38
24443394 2014
237
[Genetics of primary headache syndromes]. 38
25012921 2014
238
Calcitonin gene-related peptide and migraine with aura: A systematic review. 38
24452423 2014
239
Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A. 38
24836863 2014
240
Genetic forms of epilepsies and other paroxysmal disorders. 38
25192505 2014
241
PRRT2 and hemiplegic migraine: a complex association. 38
24928127 2014
242
Biochemical characterization of sporadic/familial hemiplegic migraine mutations. 38
24704353 2014
243
Magnetic resonance angiography evidence of vasospasm in children with suspected acute hemiplegic migraine. 38
23594822 2014
244
The prevalence of familial hemiplegic migraine with cerebellar ataxia and spinocerebellar ataxia type 6 in Portugal. 38
24898624 2014
245
Changes in (99m)Tc-ECD SPECT and magnetic resonance angiography with sporadic hemiplegic migraine in a child. 38
24662647 2014
246
Functional analysis of human Na(+)/K(+)-ATPase familial or sporadic hemiplegic migraine mutations expressed in Xenopus oocytes. 38
24921013 2014
247
Benign nocturnal alternating hemiplegia of childhood: a new case with unusual findings. 38
23820111 2014
248
A loss-of-function CACNA1A mutation causing benign paroxysmal torticollis of infancy. 38
24445160 2014
249
Arterial surgery for sporadic hemiplegic migraine: preliminary results. 38
24703384 2014
250
Synaptic gain-of-function effects of mutant Cav2.1 channels in a mouse model of familial hemiplegic migraine are due to increased basal [Ca2+]i. 38
24849341 2014
251
A novel missense mutation in CACNA1A evaluated by in silico protein modeling is associated with non-episodic spinocerebellar ataxia with slow progression. 38
24486772 2014
252
A hyperexcitability phenotype in mouse trigeminal sensory neurons expressing the R192Q Cacna1a missense mutation of familial hemiplegic migraine type-1. 38
24583041 2014
253
Hemiplegic migraine: neuroimaging findings during a hemiplegic migraine attack. 38
24512003 2014
254
Rare clinical findings in a patient with sporadic hemiplegic migraine: FDG-PET provides diminished brain metabolism at 10-year follow-up. 38
24270521 2014
255
Differential trigeminovascular nociceptive responses in the thalamus in the familial hemiplegic migraine 1 knock-in mouse: a Fos protein study. 38
24355314 2014
256
Pediatric hemiplegic migraine: role of multiple MRI techniques in evaluation of reversible hypoperfusion. 38
24142848 2014
257
Delayed recovery post anesthesia: an atypical presentation of familial hemiplegic migraine. 38
24347352 2014
258
Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene. 38
24096472 2014
259
Normoammonemic encephalopathy: solely valproate induced or multiple mechanisms? 38
24614773 2014
260
RNA expression profiling in brains of familial hemiplegic migraine type 1 knock-in mice. 38
23985897 2014
261
Calcium channels and synaptic transmission in familial hemiplegic migraine type 1 animal models. 38
28509957 2014
262
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy. 38
24136331 2014
263
A wide clinical phenotype spectrum in patients with ATP1A2 mutations. 38
24097848 2014
264
Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. 38
24356962 2014
265
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders. 38
24904274 2014
266
Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders. 38
24594579 2014
267
PRRT2: a major cause of infantile epilepsy and other paroxysmal disorders of childhood. 38
25194488 2014
268
Pharmacological correction of gating defects in the voltage-gated Ca(v)2.1 Ca²⁺ channel due to a familial hemiplegic migraine mutation. 38
24411734 2014
269
A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy. 38
23918834 2014
270
Linking a genetic defect in migraine to spreading depression in a computational model. 38
24860703 2014
271
Sturge-Weber syndrome with late onset hemiplegic migraine-like attacks and progressive unilateral cerebral atrophy. 38
24045571 2014
272
Repeated encephalopathy and hemicerebral atrophy in a patient with familial hemiplegic migraine type 1. 38
25274239 2014
273
[Migraine and epilepsy]. 38
25672693 2014
274
Sporadic hemiplegic migraine with permanent neurological deficits. 38
24117121 2014
275
Familial hemiplegic migraine and spreading depression. 38
25143767 2014
276
Channelopathies. 38
24578711 2014
277
GABAA Receptor Expression in the Forebrain of Ataxic Rolling Nagoya Mice. 38
25309056 2014
278
Phenotypes and PRRT2 mutations in Chinese families with benign familial infantile epilepsy and infantile convulsions with paroxysmal choreoathetosis. 38
24370076 2013
279
Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions. 38
23954377 2013
280
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study. 38
23459313 2013
281
Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy. 38
23838748 2013
282
Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice. 38
24294842 2013
283
Zebrafish as a novel model to assess Na+/K(+)-ATPase-related neurological disorders. 38
24091024 2013
284
The E1015K variant in the synprint region of the CaV2.1 channel alters channel function and is associated with different migraine phenotypes. 38
24108129 2013
285
Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies. 38
24498617 2013
286
The diagnostic role for susceptibility-weighted MRI during sporadic hemiplegic migraine. 38
23766355 2013
287
Possible effect of corticoids on hemiplegic attacks in severe hemiplegic migraine. 38
23831250 2013
288
Transient unilateral spatial neglect during aura in a woman with sporadic hemiplegic migraine. 38
23674829 2013
289
May a suspicious psychiatric disorder hide sporadic hemiplegic migraine? Genetic test as prompting factor for diagnosis. 38
23397224 2013
290
Nonfunctional NaV1.1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects. 38
24101488 2013
291
The molecular pathogenesis of migraine: new developments and opportunities. 38
23922230 2013
292
Monozygotic twin sisters discordant for familial hemiplegic migraine. 38
24041236 2013
293
Migraine variants--occurrence in pediatric neurology practice. 38
23688445 2013
294
Migraine genetics: Part II. 38
23919895 2013
295
Hemiplegic migraine with reversible cerebral vasoconstriction caused by ATP1A2 mutations. 38
23821026 2013
296
Behavioral evidence for photophobia and stress-related ipsilateral head pain in transgenic Cacna1a mutant mice. 38
23673147 2013
297
Sporadic hemiplegic migraine in a Nigerian woman. 38
24005593 2013
298
Lymphocyte subsets in pediatric migraine. 38
23070628 2013
299
Calcium channels and migraine. 38
23165010 2013
300
PRRT2 mutations and paroxysmal disorders. 38
23398397 2013
301
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation. 38
23761507 2013
302
Pearls and pitfalls in genetic studies of migraine. 38
23671257 2013
303
An adolescent with pseudomigraine, transient headache, neurological deficits, and lymphocytic pleocytosis (HaNDL Syndrome): case report and review of the literature. 38
23559488 2013
304
The typical duration of migraine aura: a systematic review. 38
23475294 2013
305
PRRT2 mutation causes paroxysmal kinesigenic dyskinesia and hemiplegic migraine in monozygotic twins. 38
23182655 2013
306
Divergent effects of the T1174S SCN1A mutation associated with seizures and hemiplegic migraine. 38
23398611 2013
307
[Genetics of migraine]. 38
23618705 2013
308
Clinical features of childhood-onset paroxysmal kinesigenic dyskinesia with PRRT2 gene mutations. 38
23363396 2013
309
The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels. 38
23430985 2013
310
A pediatric sporadic hemiplegic migraine case with perfusion abnormality in perfusion MRI and Diamox 99mTc-HMPAO SPECT. 38
22547402 2013
311
Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models. 38
23561701 2013
312
Effects of LPS on P2X3 receptors of trigeminal sensory neurons and macrophages from mice expressing the R192Q Cacna1a gene mutation of familial hemiplegic migraine-1. 38
22836594 2013
313
Mutation analysis of CACNA1A gene in Iranian migrainous and review literatures. 38
23961289 2013
314
SCN1A mutation associated with intractable myoclonic epilepsy and migraine headache. 38
22550089 2013
315
Familial and sporadic hemiplegic migraine: diagnosis and treatment. 38
23203776 2013
316
Cerebellar ataxia, hemiplegic migraine, and related phenotypes due to a CACNA1A missense mutation: 12-year follow-up of a large Portuguese family. 38
23407676 2013
317
Impact of 99mTc-HMPAO brain perfusion scan in the diagnosis of hemiplegic migraine. 38
23334140 2013
318
Strokes: mimics and chameleons. 38
23315456 2013
319
The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1). 38
23577145 2013
320
Recurrent transient hemiparesis in a patient with a giant persisting Eustachian valve and patent foramen ovale: atypical hemiplegic migraine or paradoxical cerebral embolism? 38
23812203 2013
321
TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine. 38
23326332 2013
322
Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations. 38
24396618 2013
323
[Migraine with prolonged atypical aura: report of two cases]. 38
23588869 2013
324
Spreading depression and the clinical correlates of migraine. 38
23907418 2013
325
Presynaptic CaV2.1 calcium channels carrying familial hemiplegic migraine mutation R192Q allow faster recovery from synaptic depression in mouse calyx of Held. 38
22956801 2012
326
Channeling headache: novel findings in the study of Ca(2+)-channels and FHM-1. 38
22991044 2012
327
Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine. 38
23171280 2012
328
PRRT2 mutations in familial infantile seizures, paroxysmal dyskinesia, and hemiplegic migraine. 38
23077026 2012
329
PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. 38
23077024 2012
330
PRRT2 mutations cause hemiplegic migraine. 38
23077016 2012
331
PRRT2 links infantile convulsions and paroxysmal dyskinesia with migraine. 38
23077017 2012
332
Familial PRRT2 mutation with heterogeneous paroxysmal disorders including paroxysmal torticollis and hemiplegic migraine. 38
22845787 2012
333
Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2). 38
22661290 2012
334
Identification of novel genes involved in migraine. 38
23030542 2012
335
Migraine headache: a review of the molecular genetics of a common disorder. 38
22940869 2012
336
Familial hemiplegic migraine with prolonged global aura: follow-up findings of subtraction ictal SPECT co-registered to MRI (SISCOM). 38
22933508 2012
337
CoEnzyme Q10 and riboflavin: the mitochondrial connection. 38
23030537 2012
338
Cerebellar ataxia by enhanced Ca(V)2.1 currents is alleviated by Ca2+-dependent K+-channel activators in Cacna1a(S218L) mutant mice. 38
23115190 2012
339
Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children. 38
22883286 2012
340
Familial hemiplegic migraine with prolonged coma and cerebellar atrophy: CACNA1A T666M mutation in a Korean family. 38
22969264 2012
341
Migraine with aura in patients over 50 years of age: the Marseille’s registry. 38
22302276 2012
342
Prolonged symptoms in sporadic hemiplegic migraine: aura or migrainous infarction? 38
23196733 2012
343
Sporadic hemiplegic migraine presenting as acute encephalopathy. 38
22136990 2012
344
Migraine: a disorder of brain excitatory-inhibitory balance? 38
22633369 2012
345
A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation. 38
22759692 2012
346
Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels. 38
22549042 2012
347
A young man presenting with acute encephalopathy, hemiparesis, and headache. 38
19782500 2012
348
Nitric oxide modulation of low-frequency oscillations in cortical vessels in FHM--a NIRS study. 38
22352839 2012
349
R583Q CACNA1A variant in SHM1 and ataxia: case report and literature update. 38
22527033 2012
350
Stroke and familial hemiplegic migraine. 38
22608661 2012
351
Long-term outcome of cognitive functions, emotional behavior, and quality of life in a family with familial hemiplegic migraine. 38
22596110 2012
352
Alcohol as a dietary trigger of primary headaches: what triggering site could be compatible? 38
22644204 2012
353
[Migraine: from genetics to environment]. 38
22891490 2012
354
Migraine-induced epistaxis and sporadic hemiplegic migraine: unusual features in the same patient. 38
22807908 2012
355
Lombardia GENS: a collaborative registry for monogenic diseases associated with stroke. 38
23158583 2012
356
A genotype-phenotype analysis of the 8q22.1 variant in migraine with aura. 38
22103325 2012
357
Late cytotoxic edema in 2 children with hemiplegia: hemiplegic migraine or stroke? 38
22404149 2012
358
Safety and efficacy of flunarizine in childhood migraine: 11 years' experience, with emphasis on its effect in hemiplegic migraine. 38
22268377 2012
359
A single-fibre electromyography study of neuromuscular transmission in patients with cluster headache. 38
22581595 2012
360
Effects of familial hemiplegic migraine type 1 mutation T666M on voltage-gated calcium channel activities in trigeminal ganglion neurons. 38
22190617 2012
361
Perfusion-weighted MR imaging in persistent hemiplegic migraine. 38
21833737 2012
362
[Familial hemiplegic migraine type 2: two paediatric case reports]. 38
22314763 2012
363
Sporadic hemiplegic migraine. 38
22410518 2012
364
Detection of a novel mutation in the CACNA1A gene. 38
22784462 2012
365
Sporadic hemiplegic migraine with normal imaging as the initial manifestation of CADASIL. 38
22250206 2012
366
Migraine- and dystonia-related disease-mutations of Na+/K+-ATPases: relevance of behavioral studies in mice to disease symptoms and neurological manifestations in humans. 38
22067897 2012
367
Neurovascular changes in prolonged migraine aura in FHM with a novel ATP1A2 gene mutation. 38
22013243 2012
368
Coexistence of hemiplegic migraine with SUNCT or SUNA: a case series. 38
22238357 2012
369
Alternating hemiplegia of childhood: metabolic studies in the largest European series of patients. 38
21945173 2012
370
Neuronal P/Q-type calcium channel dysfunction in inherited disorders of the CNS. 38
22249839 2012
371
[Cortical spreading depression and molecular genetics in migraine]. 38
23196498 2012
372
CaV2.1 voltage activated calcium channels and synaptic transmission in familial hemiplegic migraine pathogenesis. 38
22074995 2012
373
Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations. 38
22144569 2012
374
Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine. 38
22117059 2012
375
Migraine with aura in the locker room: three case reports. 38
21830148 2012
376
Posttraumatic dystonia and hemiplegic migraine: different expressions of neuronal hyperexcitability? 38
22217613 2012
377
Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine. 38
22005682 2011
378
Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate. 38
22030984 2011
379
Acute striatal necrosis in hemiplegic migraine with de novo CACNA1A mutation. 38
22082423 2011
380
Hemiplegic migraine, seizures, progressive spastic paraparesis, mood disorder, and coma in siblings with low systemic serotonin. 38
22013141 2011
381
Primary leptomeningeal melanocytosis in a 10-year-old girl: a challenging diagnosis with a poor prognosis. 38
21670389 2011
382
Early-onset cerebellar atrophy associated with mutation in the CACNA1A gene. 38
22000314 2011
383
Migraine: Role of the TRESK two-pore potassium channel. 38
21855646 2011
384
Transient nonverbal learning disorder in a child suffering from Familial Hemiplegic Migraine. 38
21908445 2011
385
Immunohistochemical characterization of calcitonin gene-related peptide in the trigeminal system of the familial hemiplegic migraine 1 knock-in mouse. 38
21893556 2011
386
Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model. 38
21958474 2011
387
Hemiplegic migraine aura begins with cerebral hypoperfusion: imaging in the acute phase. 38
21797860 2011
388
Hemiconvulsion-hemiplegia-epilepsy syndrome associated with CACNA1A S218L mutation. 38
21824570 2011
389
Trigger factors for familial hemiplegic migraine. 38
21784774 2011
390
Head tremor related to CACNA1A mutations. 38
21768184 2011
391
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2. 38
21731499 2011
392
Migraine genes and the relation to gender. 38
21631474 2011
393
Identification of molecular genetic factors that influence migraine. 38
21519858 2011
394
One case of sporadic hemiplegic migraine with multiple pulmonary arteriovenous malformation. 38
21246241 2011
395
One hundred years of migraine research: major clinical and scientific observations from 1910 to 2010. 38
21521208 2011
396
Sporadic and familial hemiplegic migraine: pathophysiological mechanisms, clinical characteristics, diagnosis, and management. 38
21458376 2011
397
The genetic features of 24 patients affected by familial and sporadic hemiplegic migraine. 38
21533730 2011
398
Genetic diagnosis and acetazolamide treatment of familial hemiplegic migraine. 38
20542393 2011
399
Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine. 38
21457239 2011
400
Multimodal neuroimaging in a child with sporadic hemiplegic migraine: a contribution to understanding pathogenesis. 38
21172953 2011
401
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. 38
21490217 2011
402
Prolonged sporadic hemiplegic migraine associated with a novel de novo missense ATP1A2 gene mutation. 38
21352219 2011
403
Habituation of evoked responses is greater in patients with familial hemiplegic migraine than in controls: a contrast with the common forms of migraine. 38
20727009 2011
404
Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from wild-type and R192Q Cav2.1 Knock-in mice: implications for basic mechanisms of migraine pain. 38
21389219 2011
405
Neurological complications without eclampsia during pregnancy in Turkey. 38
21159040 2011
406
Role of different voltage-gated Ca2+ channels in cortical spreading depression: specific requirement of P/Q-type Ca2+ channels. 38
21150292 2011
407
[Migraine: advances in the pathophysiology and treatment]. 38
21404609 2011
408
Treatment of acute migraine headache. 38
21302868 2011
409
Recurrent stroke due to a novel voltage sensor mutation in Cav2.1 responds to verapamil. 38
21183743 2011
410
Feasibility of combined epicranial temporal and occipital neurostimulation: treatment of a challenging case of headache. 38
21267040 2011
411
Familial hemicrania continua. 38
20956404 2011
412
A novel mutation in CACNA1A associated with hemiplegic migraine, cerebellar dysfunction and late-onset cognitive decline. 38
21035146 2011
413
A long-term follow-up study of 18 patients with sporadic hemiplegic migraine. 38
20974584 2011
414
The digiti quinti sign in hemiplegic migraine. 38
20974599 2011
415
Sporadic hemiplegic migraine with seizures and transient MRI abnormalities. 38
22937333 2011
416
Pediatric hemiplegic migraine: susceptibility weighted and MR perfusion imaging abnormality. 38
20821201 2010
417
The dynamic regulation of cortical excitability is altered in episodic ataxia type 2. 38
21126994 2010
418
Moyamoya disease presented as a case of hemiplegic migraine. 38
22798438 2010
419
Ranolazine selectively blocks persistent current evoked by epilepsy-associated Naν1.1 mutations. 38
20735403 2010
420
Contribution of calcium-dependent facilitation to synaptic plasticity revealed by migraine mutations in the P/Q-type calcium channel. 38
20937883 2010
421
Dihydroergotamine and its use in migraine with posterior fossa symptoms. 38
20533960 2010
422
Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. 38
20855363 2010
423
Familial hemiplegic migraine. 38
20816023 2010
424
De novo mutations in ATP1A2 and CACNA1A are frequent in early-onset sporadic hemiplegic migraine. 38
20837964 2010
425
Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice. 38
20631222 2010
426
Differential regulation of Purkinje cell dendritic spines in rolling mouse Nagoya (tg/tg), P/Q type calcium channel (α1(A)/Ca(v)2.1) mutant. 38
21212861 2010
427
Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine. 38
20798035 2010
428
Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase. 38
20720542 2010
429
Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain. 38
20735819 2010
430
A wide spectrum of clinical, neurophysiological and neuroradiological abnormalities in a family with a novel CACNA1A mutation. 38
20682717 2010
431
Child neurology: Migraine with aura in children. 38
20679627 2010
432
Sporadic hemiplegic migraine in children. 38
20739784 2010
433
Calcium channelopathies in inherited neurological disorders: relevance to drug screening for acquired channel disorders. 38
20582871 2010
434
Quantitative cortical synapse proteomics of a transgenic migraine mouse model with mutated Ca(V)2.1 calcium channels. 38
20391530 2010
435
CaV2.1 channelopathies. 38
20204399 2010
436
Sporadic hemiplegic migraine in children: a report of two new cases. 38
20739815 2010
437
History of migraine with aura and cortical spreading depression from 1941 and onwards. 38
19740119 2010
438
Gain of function in FHM-1 Cav2.1 knock-in mice is related to the shape of the action potential. 38
20484531 2010
439
Cognitive functions, emotional behavior, and quality of life in familial hemiplegic migraine. 38
20535059 2010
440
Cerebral perfusion changes in hemiplegic migraine: illustrated by Tc-99m ECD brain perfusion scan. 38
20479602 2010
441
Insights into migraine mechanisms and CaV2.1 calcium channel function from mouse models of familial hemiplegic migraine. 38
20194127 2010
442
Link between confusional migraine, hemiplegic migraine and episodic ataxia type 2: hypothesis, family genealogy, gene typing and classification. 38
19624685 2010
443
What have we learnt from triggering migraine? 38
20173638 2010
444
[Sporadic hemiplegic migraine-like headache in a patient with systemic lupus erythematosus]. 38
20535984 2010
445
Partially reversible cortical metabolic dysfunction in familial hemiplegic migraine with prolonged aura. 38
20236346 2010
446
Abnormal MRI in a patient with 'headache with neurological deficits and CSF lymphocytosis (HaNDL)'. 38
19614699 2010
447
Clinical and neuroimaging evidence of interictal cerebellar dysfunction in FHM2. 38
19673908 2010
448
A homolog of FHM2 is involved in modulation of excitatory neurotransmission by serotonin in C. elegans. 38
20442779 2010
449
[Off-label use of acetazolamide in a patient with familial hemiplegic migraine and concomitant psychotic episodes]. 38
20148382 2010
450
A genome-wide linkage study of bipolar disorder and co-morbid migraine: replication of migraine linkage on chromosome 4q24, and suggestion of an overlapping susceptibility region for both disorders on chromosome 20p11. 38
19819557 2010
451
Migraine variants and beyond. 38
21049701 2010
452
Sporadic hemiplegic migraine and CREST syndrome. 38
20130953 2010
453
Management of sporadic and familial hemiplegic migraine. 38
20187861 2010
454
Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities. 38
20100831 2010
455
Headache associated with moyamoya disease: a case story and literature review. 38
20012551 2010
456
Coexisting typical migraine in familial hemiplegic migraine. 38
20157162 2010
457
Genetics of headaches. 38
20816412 2010
458
Biological science of headache channels. 38
20816411 2010
459
Phenotypic variability of episodic ataxia type 2 mutations: a family study. 38
20639635 2010
460
A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis. 38
20080591 2010
461
Neurological picture. Cortical oedema: a link between delusional misidentification syndromes and hemiplegic migraine. 38
20019221 2010
462
High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. 38
20186955 2010
463
A case of Sturge-Weber syndrome with symptomatic hemiplegic migraine: clinical and multimodality imaging data during a prolonged attack. 38
19733861 2009
464
Clinical description of hemodialysis headache in end-stage renal disease patients. 38
20069204 2009
465
The FHM1 mutation S218L: a severe clinical phenotype? A case report and review of the literature. 38
19438926 2009
466
Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice. 38
19854154 2009
467
Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation. 38
19874388 2009
468
Central sensory-motor deficit after uneventful single-dose spinal morphine administration in a patient with preexisting migraine headaches. 38
19843810 2009
469
[Sporadic hemiplegic migraine in a 14-year-old boy--a case report]. 38
20054761 2009
470
Cessation of sporadic hemiplegic migraine attacks after patent foramen ovale closure. 38
19758362 2009
471
Early seizures and cerebral oedema after trivial head trauma associated with the CACNA1A S218L mutation. 38
19520699 2009
472
Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice. 38
19847904 2009
473
Parental SCN1A mutation mosaicism in familial Dravet syndrome. 38
19673951 2009
474
Novel mutations affecting the Na, K ATPase alpha model complex neurological diseases and implicate the sodium pump in increased longevity. 38
19455355 2009
475
Migrainous infarction as a complication of sporadic hemiplegic migraine in childhood. 38
19838529 2009
476
A case of atypical sporadic hemiplegic migraine associated with PFO and hypoplasia of vertebro-basilar system. 38
19421707 2009
477
GLUT1 gene mutations cause sporadic paroxysmal exercise-induced dyskinesias. 38
19630075 2009
478
CACNA1A nonsense mutation is associated with basilar-type migraine and episodic ataxia type 2. 38
19486177 2009
479
Familial hemiplegic migraine: linkage to chromosome 14q32 in a Spanish kindred. 38
19153782 2009
480
Molecular genetics of migraine. 38
19455354 2009
481
Basilar-type migraine. 38
19457282 2009
482
Pediatric migraine. 38
19289227 2009
483
Transient neurologic dysfunction in migraine. 38
19289220 2009
484
A note on the digiti quinti sign in hemiplegic migraine. 38
19025551 2009
485
[Case of sporadic hemiplegic migraine with cerebellar ataxia]. 38
19594104 2009
486
Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population. 38
19368856 2009
487
Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine. 38
19372756 2009
488
Cerebral oedema in episodic ataxia. 38
19402571 2009
489
The headache of a hyperactive calcium channel. 38
19285460 2009
490
Ca(V)2.1 P/Q-type calcium channel alternative splicing affects the functional impact of familial hemiplegic migraine mutations: implications for calcium channelopathies. 38
19242091 2009
491
Profound encephalopathy with complete recovery in three children with familial hemiplegic migraine. 38
19317760 2009
492
First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy. 38
19220312 2009
493
Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice. 38
19285472 2009
494
FHM3 in familial hemiplegic migraine is more resistant to mutation than FHM1 and FHM2. 38
19007941 2009
495
Genetic calcium signaling abnormalities in the central nervous system: seizures, migraine, and autism. 38
19154521 2009
496
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1. 38
19104150 2009
497
Deciphering migraine. 38
19104145 2009
498
Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report. 38
18624711 2009
499
Newly characterised 5' and 3' regions of CACNA1A gene harbour mutations associated with Familial Hemiplegic Migraine and Episodic Ataxia. 38
18976783 2009
500
Translational research in epilepsy genetics: sodium channels in man to interneuronopathy in mouse. 38
19139296 2009
501
The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. 38
18957371 2009
502
Sporadic hemiplegic migraine: report of a case with clinical and radiological features. 38
18810316 2008
503
Intravenous nimodipine worsening prolonged attack of familial hemiplegic migraine. 38
18846413 2008
504
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2. 38
18728015 2008
505
CACNA1A R1347Q: a frequent recurrent mutation in hemiplegic migraine. 38
18400034 2008
506
Stepwise developmental regression associated with novel CACNA1A mutation. 38
18940563 2008
507
A high-density association screen of 155 ion transport genes for involvement with common migraine. 38
18676988 2008
508
The S218L familial hemiplegic migraine mutation promotes deinhibition of Ca(v)2.1 calcium channels during direct G-protein regulation. 38
18581134 2008
509
Inherited neuronal ion channelopathies: new windows on complex neurological diseases. 38
19005038 2008
510
A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine. 38
18361423 2008
511
Genetic analysis of 27 Spanish patients with hemiplegic migraine, basilar-type migraine and childhood periodic syndromes. 38
18644040 2008
512
Downbeat positioning nystagmus is a common clinical feature despite variable phenotypes in an FHM1 family. 38
18670797 2008
513
The neurogenic basis of migraine. 38
19006559 2008
514
Migraine and epilepsy: genetically linked? 38
18759542 2008
515
Migraine genetics. 38
18759544 2008
516
Calcitonin gene-related peptide does not cause the familial hemiplegic migraine phenotype. 38
18779512 2008
517
Topiramate-associated worsening symptoms in a patient with familial hemiplegic migraine. 38
18603263 2008
518
Electroencephalographic changes and seizures in familial hemiplegic migraine patients with the CACNA1A gene S218L mutation. 38
18313928 2008
519
Divergent sodium channel defects in familial hemiplegic migraine. 38
18621678 2008
520
Prolonged hemiplegic migraine. 38
21063345 2008
521
Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation. 38
18498390 2008
522
Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel. 38
18632931 2008
523
Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies. 38
18597946 2008
524
Animal models of migraine headache and aura. 38
18451713 2008
525
Hemiplegic migraine associated with interscalene block and general anaesthesia. 38
18477293 2008
526
Is migraine a genetic illness? The various forms of migraine share a common genetic cause. 38
18545897 2008
527
Migraine: a genetic disease? 38
18545896 2008
528
[The Na+,K+ pump continues to cause surprise]. 38
18492448 2008
529
Familial hemiplegic migraine type 1 shows no hypersensitivity to nitric oxide. 38
18384418 2008
530
Migraine as a sex-conditioned inherited disorder: evidences from China and the world. 38
18369391 2008
531
Familial hemiplegic migraine type 2 does not share hypersensitivity to nitric oxide with common types of migraine. 38
18294248 2008
532
Expansion of the phenotypic spectrum of the CACNA1A T666M mutation: a family with familial hemiplegic migraine type 1, cerebellar atrophy and mental retardation. 38
18279427 2008
533
The primary headaches: genetics, epigenetics and a behavioural genetic model. 38
18345478 2008
534
Release of glutamate and CGRP from trigeminal ganglion neurons: Role of calcium channels and 5-HT1 receptor signaling. 38
18416824 2008
535
Epilepsy as part of the phenotype associated with ATP1A2 mutations. 38
18028407 2008
536
Cessation of hemiplegic migraine auras with greater occipital nerve blockade: a comment. 38
18205798 2008
537
[Familial and sporadic hemiplegic migraine]. 38
18405771 2008
538
[Familial hemiplegic migraine resulting in recurrent coma]. 38
18380388 2008
539
A review of the genetic relation between migraine and epilepsy. 38
18197881 2008
540
[Epilepsy in Israel--2008]. 38
18357670 2008
541
Progressive cerebellar ataxia with variable episodic symptoms--phenotypic diversity of R1668W CACNA1A mutation. 38
18437043 2008
542
Hypothesis on neurophysiopathological mechanisms linking epilepsy and headache. 38
18191908 2008
543
Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamil. 38
17614229 2008
544
Migraine: sex-influenced trait model? 38
18289799 2008
545
Familial hemiplegic migraine. 38
19185185 2008
546
Analysis of calcium ion homeostasis and mitochondrial function in cerebellar granule cells of adult CaV 2.1 calcium ion channel mutant mice. 38
18367436 2008
547
Investigation of the NOTCH3 and TNFSF7 genes on C19p13 as candidates for migraine. 38
19018300 2008
548
Novel mutation confirms seizure locus SCN1A is also familial hemiplegic migraine locus FHM3. 38
18021921 2007
549
Molecular mechanisms of migraine? 38
17987250 2007
550
Association between cortical metabolite levels and clinical manifestations of migrainous aura: an MR-spectroscopy study. 38
17956910 2007
551
Na,K-ATPase and the role of alpha isoforms in behavior. 38
18044013 2007
552
PLEDs: clinical correlates. 38
18062453 2007
553
Case 125: hemiplegic migraine. 38
17940312 2007
554
Investigation of neuromuscular transmission in some rare types of migraine. 38
17919307 2007
555
Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A. 38
17376154 2007
556
[P/Q-type voltage-dependent calcium channels in neurological disease]. 38
17573560 2007
557
Adult-onset hemiplegic migraine with cortical enhancement and oedema. 38
17645764 2007
558
Unusual headache syndromes in children. 38
17894929 2007
559
Transient exacerbation of hemiplegia following minor head trauma in Sturge-Weber syndrome. 38
17718827 2007
560
Apnoeic spells following general anaesthesia in a patient with familial hemiplegic migraine. 38
17697227 2007
561
Migraine in Thai children: prevalence in junior high school students. 38
17890411 2007
562
Familial hemiplegic migraine: permanent attack-related neurologic deficits. 38
17883529 2007
563
Treatment of hemiplegic migraine with triptans. 38
17718700 2007
564
Association analysis of chromosome 1 migraine candidate genes. 38
17727731 2007
565
Cessation of hemiplegic migraine auras with greater occipital nerve blockade. 38
17578545 2007
566
The cerebellum and migraine. 38
17578530 2007
567
Migraine: gene mutations and functional consequences. 38
17495624 2007
568
Presentation of hemiplegic migraine--hemiplegia and hemi-sensory loss following general anaesthesia. 38
17591140 2007
569
Genetics in primary headaches. 38
17563838 2007
570
Recent advances in the pharmacogenomics of pain and headache. 38
17508172 2007
571
Genetic models of migraine. 38
17502463 2007
572
The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online. 38
17397047 2007
573
Prolonged hemiplegic episodes in children due to mutations in ATP1A2. 38
17435187 2007
574
Familial hemiplegic migraine. 38
17395138 2007
575
Challenges in the design and conduct of therapeutic trials in channel disorders. 38
17395129 2007
576
Early-onset progressive ataxia associated with the first CACNA1A mutation identified within the I-II loop. 38
17292920 2007
577
The genetic spectrum of a population-based sample of familial hemiplegic migraine. 38
17142831 2007
578
The search for migraine genes: an overview of current knowledge. 38
17187176 2007
579
Establishing the genetic heterogeneity of familial hemiplegic migraine. 38
17235123 2007
580
[Role of P/Q calcium channel in familial hemiplegic migraine]. 38
17212932 2007
581
Recent advances in understanding migraine mechanisms, molecules and therapeutics. 38
17141570 2007
582
Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine. 38
17952365 2007
583
Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice. 38
17234593 2007
584
Heredity, genes, and headache. 38
17048152 2006
585
Interactions between migraine and stroke. 38
17032572 2006
586
[Genetics of migraine]. 38
16915377 2006
587
Alternating hemiplegia of childhood: no mutations in the glutamate transporter EAAT1. 38
17236110 2006
588
Diagnostic challenge--is this really a stroke? 38
17019457 2006
589
Mutation analysis of CACNA1A and ATP1A2 genes in Brazilian FHM families. 38
17119788 2006
590
Unilateral spatial neglect in a child with hemiplegic migraine. 38
16919072 2006
591
The spectrum of benign infantile seizures. 38
16837167 2006
592
Imaging abnormalities in sporadic hemiplegic migraine on conventional MRI, diffusion and perfusion MRI and MRS. 38
16886937 2006
593
Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4. 38
16866717 2006
594
Cerebrospinal fluid sodium increases in migraine. 38
16866716 2006
595
Genetic biomarkers for migraine. 38
16866710 2006
596
New insights into migraine pathophysiology. 38
16702838 2006
597
Genetics of migraine: an update. 38
16927960 2006
598
Migraine with aura: new understanding from clinical epidemiologic studies. 38
16702837 2006
599
Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families. 38
16822249 2006
600
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine. 38
16538223 2006
601
[Changes of electroencephalographic findings in a case of migraine with various neurological symptoms]. 38
16715937 2006
602
The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. 38
16508934 2006
603
Haplotype-based systematic association studies of ATP1A2 in migraine with aura. 38
16508935 2006
604
Minor head trauma-induced sporadic hemiplegic migraine coma. 38
16638514 2006
605
[ATP1A2: a key player in familial hemiplegic migraine]. 38
16597394 2006
606
Sporadic and familial hemiplegic migraine: diagnosis and treatment. 38
16628531 2006
607
Basilar-type migraine: clinical, epidemiologic, and genetic features. 38
16567706 2006
608
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. 38
16472342 2006
609
A novel ATP1A2 mutation in a family with FHM type II. 38
16472340 2006
610
Implications of clinical subtypes of migraine with aura. 38
16492238 2006
611
Cough-induced hemiplegic migraine with impaired consciousness in cystic fibrosis. 38
16372353 2006
612
Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation. 38
16437583 2006
613
Early onset, non fluctuating spinocerebellar ataxia and a novel missense mutation in CACNA1A gene. 38
16325861 2006
614
[Mechanisms and genetics of migraine]. 38
16841522 2006
615
Familial basilar migraine associated with a new mutation in the ATP1A2 gene. 38
16344534 2005
616
Pain research update from a genetic point of view. 38
17177767 2005
617
No evidence of ATP1A2 involvement in 12 multiplex Italian families with benign familial infantile seizures. 38
16026932 2005
618
Noradrenergic blockade prevents attacks in a model of episodic dysfunction caused by a channelopathy. 38
16242631 2005
619
Symptomatic sporadic hemiplegic migraine. 38
16232163 2005
620
[Migraine update]. 38
16218383 2005
621
[Genetic analysis of migraine headache: a review]. 38
16218382 2005
622
Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family. 38
16178956 2005
623
Rare missense variants in ATP1A2 in families with clustering of common forms of migraine. 38
16110494 2005
624
A single-fibre EMG study of neuromuscular transmission in migraine patients. 38
16162259 2005
625
Autopsy case of acute encephalopathy linked to familial hemiplegic migraine with cerebellar atrophy and mental retardation. 38
16193840 2005
626
[Single photon emission computed tomography findings in a case of alternating hemiplegia of childhood in relation to migraine]. 38
16164248 2005
627
Genomewide significant linkage to migrainous headache on chromosome 5q21. 38
16080125 2005
628
ATP1A2 mutations in 11 families with familial hemiplegic migraine. 38
16088919 2005
629
Migraine: new treatment options from molecular biology. 38
16162089 2005
630
Migraine: new molecular mechanisms. 38
16061523 2005
631
Alterations in the alpha2 isoform of Na,K-ATPase associated with familial hemiplegic migraine type 2. 38
16037212 2005
632
[Episodic ataxias]. 38
16100538 2005
633
Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. 38
16054936 2005
634
[Molecular genetics of migraine]. 38
16141949 2005
635
Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II. 38
15985592 2005
636
Gating deficiency in a familial hemiplegic migraine type 1 mutant P/Q-type calcium channel. 38
15795222 2005
637
Familial Paroxysmal Kinesigenic Dyskinesia 38
20301633 2005
638
Migraine genetics: an update. 38
15907261 2005
639
Peripheral genotype-phenotype correlations in Asian Indians with type 2 diabetes mellitus. 38
16121806 2005
640
Single-fiber EMG in familial hemiplegic migraine. 38
15883351 2005
641
Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma. 38
15743764 2005
642
Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation. 38
15843000 2005
643
Diffusion- and perfusion-weighted MR imaging in persistent migrainous visual disturbances. 38
15839846 2005
644
Current issues in migraine genetics. 38
20396468 2005
645
Migraine pathophysiology. 38
15833086 2005
646
Familial hemiplegic migraine: more than just a headache. 38
15728276 2005
647
Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca2+ channel activity and inhibitory synaptic transmission. 38
15699344 2005
648
1H-MRS alterations in the cerebellum of patients with familial hemiplegic migraine type 1. 38
15728280 2005
649
A highly polymorphic poly-glutamine stretch in the potassium channel KCNN3 in migraine. 38
15705118 2005
650
Advances in the understanding of headache. 38
16207800 2005
651
Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness. 38
16111830 2005
652
Chromosome 19p13 loci in Finnish migraine with aura families. 38
15449251 2005
653
[Basilar-type migraine: pathophysiology, symptoms and signs, and treatment]. 38
16419573 2005
654
Preventive treatment of migraine. 38
16622394 2005
655
[Is migraine a neuronal channelopothy?]. 38
16419572 2005
656
Sporadic hemiplegic migraine. 38
15566415 2004
657
Severe hemiplegic migraine attack precipitated by fentanyl sedation for esophagogastroscopy. 38
15623730 2004
658
Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects. 38
15448138 2004
659
Preventing disturbing migraine aura with lamotrigine: an open study. 38
15546267 2004
660
Single-fiber EMG in familial hemiplegic migraine. 38
15557518 2004
661
[Recurrent hemispheric symptoms without proof of ischemia]. 38
15536580 2004
662
[An update on the familial headache syndromes]. 38
15651339 2004
663
Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2. 38
15534763 2004
664
Familial hemiplegic migraine, neuropsychiatric symptoms, and Erdheim-Chester disease. 38
15447701 2004
665
The physiopathology of migraine: the contribution of genetics. 38
15549578 2004
666
Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2. 38
15308625 2004
667
Childhood epilepsy, familial hemiplegic migraine, cerebellar ataxia, and a new CACNA1A mutation. 38
15452324 2004
668
A G301R Na+/K+ -ATPase mutation causes familial hemiplegic migraine type 2 with cerebellar signs. 38
15459825 2004
669
[From gene to disease; familial hemiplegic migraine as a result of mutations in a sodium-potassium pump gene]. 38
15495990 2004
670
Presynaptic Ca2+ channels compete for channel type-preferring slots in altered neurotransmission arising from Ca2+ channelopathy. 38
15294146 2004
671
Elicited repetitive daily blindness: a new familial disorder related to migraine and epilepsy. 38
15277634 2004
672
Clinical characteristics of 362 patients with familial migraine with aura. 38
15196299 2004
673
Genes and migraine. 38
15510232 2004
674
Familial hemiplegic migraine: follow-up findings of diffusion-weighted magnetic resonance imaging (MRI), perfusion-MRI and [99mTc] HMPAO-SPECT in a patient with prolonged hemiplegic aura. 38
15196295 2004
675
Challenging or difficult headache patients. 38
15172517 2004
676
Recent findings in headache genetics. 38
15167062 2004
677
Sporadic hemiplegic migraine. 38
15115642 2004
678
Toward a molecular genetic classification of familial hemiplegic migraine. 38
15115644 2004
679
Migraine aura: new information on underlying mechanisms. 38
15167063 2004
680
A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2. 38
15133718 2004
681
Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation. 38
15174025 2004
682
[Genetics of migraines: from ionic channels to single nucleotide polymorphisms?]. 38
15346975 2004
683
Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants. 38
15159495 2004
684
[Familial hemiplegic migraine]. 38
15174668 2004
685
Genetics of the epilepsies. 38
15021241 2004
686
EEG in hemiplegic migraine. 38
15069274 2004
687
Migraine aura: a knockin mouse with a knockout message. 38
15003166 2004
688
A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. 38
15003170 2004
689
Vertigo and dizziness related to migraine: a diagnostic challenge. 38
14728703 2004
690
Familial hemiplegic migraine. 38
14748777 2004
691
Deciphering migraine mechanisms: clues from familial hemiplegic migraine genotypes. 38
14755732 2004
692
Efficacy and tolerability of sumatriptan tablets in a fast-disintegrating, rapid-release formulation for the acute treatment of migraine: results of a multicenter, randomized, placebo-controlled study. 38
15038944 2004
693
A novel R1347Q mutation in the predicted voltage sensor segment of the P/Q-type calcium-channel alpha-subunit in a family with progressive cerebellar ataxia and hemiplegic migraine. 38
15032980 2004
694
New CACNA1A gene mutation in a case of familial hemiplegic migraine with status epilepticus. 38
15240985 2004
695
Functional effects of Na+,K+-ATPase gene mutations linked to familial hemiplegic migraine. 38
15970628 2004
696
The molecular genetics of migraine. 38
15513297 2004
697
Ca2+ channels as targets of neurological disease: Lambert-Eaton Syndrome and other Ca2+ channelopathies. 38
15000529 2003
698
New discoveries about the second gene for familial hemiplegic migraine, ATP1A2. 38
14636773 2003
699
Headache and facial pain in children and adolescents. 38
15025014 2003
700
Sporadic hemiplegic migraine is an aetiologically heterogeneous disorder. 38
14616935 2003
701
[Genetic aspects of migraine]. 38
14600747 2003
702
Significant linkage to migraine with aura on chromosome 11q24. 38
12915447 2003
703
Voltage-dependent calcium channels are involved in neurogenic dural vasodilatation via a presynaptic transmitter release mechanism. 38
12970082 2003
704
Pseudomigraine with lymphocytic pleocytosis: a calcium channelopathy? Clinical description of 10 cases and genetic analysis of the familial hemiplegic migraine gene CACNA1A. 38
12940811 2003
705
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. 38
12953268 2003
706
Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil. 38
12963781 2003
707
Increased risk of migraine with typical aura in probands with familial hemiplegic migraine and their relatives. 38
12823495 2003
708
Migraine genetics. 38
12720601 2003
709
Familial hemiplegic migraine. 38
12756128 2003
710
Serial MRI in a case of familial hemiplegic migraine. 38
12669159 2003
711
Expanding the phenotypic spectrum of the CACNA1A gene T666M mutation: a description of 5 families with familial hemiplegic migraine. 38
12756131 2003
712
Phenotypes of spinocerebellar ataxia type 6 and familial hemiplegic migraine caused by a unique CACNA1A missense mutation in patients from a large family. 38
12707077 2003
713
Familial hemiplegic migraine type 2 is linked to 0.9Mb region on chromosome 1q23. 38
12601705 2003
714
Absence of known familial hemiplegic migraine (FHM) mutations in the CACNA1A gene in patients with common migraine: implications for genetic testing. 38
12705332 2003
715
Acetazolamide acts on neuromuscular transmission abnormalities found in some migraineurs. 38
12603362 2003
716
Second gene identified for familial hemiplegic migraine. 38
12849225 2003
717
Evidence for a separate type of migraine with aura: sporadic hemiplegic migraine. 38
12601098 2003
718
Sporadic hemiplegic migraine: stamp collecting or food for thought? 38
12601089 2003
719
Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. 38
12539047 2003
720
A locus for migraine without aura maps on chromosome 14q21.2-q22.3. 38
12474141 2003
721
Spinocerebellar ataxia type 6 and episodic ataxia type 2: differences and similarities between two allelic disorders. 38
14526175 2003
722
Treatment of sporadic hemiplegic migraine with calcium-channel blocker verapamil. 38
12525732 2003
723
The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. 38
12527722 2003
724
Prolonged cortical electrical depression and diffuse vasospasm without ischemia in a case of severe hemiplegic migraine during pregnancy. 38
12864763 2003
725
A case of hemeplegic migraine with leptomeningeal angiomatosis. 38
12577115 2002
726
Familial hemiplegic migraine mutations increase Ca(2+) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons. 38
12235360 2002
727
Migraine with aura is not linked to the FHM gene CACNA1A or the chromosomal region, 19p13. 38
12370474 2002
728
Multimodal functional imaging of prolonged neurological deficits in a patient suffering from familial hemiplegic migraine. 38
12384224 2002
729
Migraine: preventive treatment. 38
12230591 2002
730
The genetics of migraine. 38
12849426 2002
731
Prolonged hemiplegic migraine associated with unilateral hyperperfusion on perfusion weighted magnetic resonance imaging. 38
12122185 2002
732
Benign paroxysmal torticollis of infancy: four new cases and linkage to CACNA1A mutation. 38
12162387 2002
733
Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4. 38
12119109 2002
734
The neuronal channelopathies. 38
12023309 2002
735
Calcium channel mutations and migraine. 38
12045730 2002
736
Magnetic resonance angiogram evidence of vasospasm in familial hemiplegic migraine. 38
12174974 2002
737
An epidemiological survey of hemiplegic migraine. 38
12110112 2002
738
A population-based study of familial hemiplegic migraine suggests revised diagnostic criteria. 38
12023326 2002
739
Mutation analysis of the CACNA1A calcium channel subunit gene in 27 patients with sporadic hemiplegic migraine. 38
12056940 2002
740
Japanese cases of familial hemiplegic migraine with cerebellar ataxia carrying a T666M mutation in the CACNA1A gene. 38
11971066 2002
741
Familial hemiplegic migraine: clinical features and probable linkage to chromosome 1 in an Italian family. 38
12111614 2002
742
Contrasts in cortical magnesium, phospholipid and energy metabolism between migraine syndromes. 38
11971091 2002
743
Is the CACNA1A gene involved in familial migraine with aura? 38
12111613 2002
744
A typical migraine susceptibility region localizes to chromosome 1q31. 38
12030327 2002
745
P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? 38
11880534 2002
746
[Ion channel abnormalities ("channelopathies") in neurologic diseases]. 38
11883365 2002
747
Hemiplegic cluster. 38
12005289 2002
748
Calcium channels and channelopathies of the central nervous system. 38
11890456 2002
749
Efficacy and tolerability of acetazolamide in migraine prophylaxis: a randomised placebo-controlled trial. 38
11985388 2002
750
Idiopathic intracranial hypertension presenting as hemiplegic migraine. 38
12222727 2002
751
Hemiplegic migraine with prolonged symptoms: case report. 38
11913583 2002
752
[Migraine(basilar migraine, hemiplegic migraine, CADSIL)]. 38
12483910 2002
753
Spinocerebellar ataxia type 6 and episodic ataxia type 2 in a Korean family. 38
11748369 2001
754
Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. 38
11735221 2001
755
[Channelopathy]. 38
12235844 2001
756
[Clinical progress in headache]. 38
12235833 2001
757
CACNA1A gene polymorphisms in cluster headache. 38
11843866 2001
758
Investigation of the CACNA1A gene as a candidate for typical migraine susceptibility. 38
11803518 2001
759
[Familial hemiplegic migraine]. 38
15775664 2001
760
Clinical and molecular correlations in spinocerebellar ataxia type 6: a study of 24 Dutch families. 38
11708993 2001
761
[Molecular genetic findings in migraine]. 38
11723684 2001
762
Triptans in the treatment of basilar migraine and migraine with prolonged aura. 38
11903526 2001
763
Familial hemiplegic migraine and its abortive therapy with intravenous verapamil. 38
11706128 2001
764
Familial hemiplegic migraine: a ion channel disorder. 38
11719257 2001
765
[Channelopathies in neurology]. 38
11784953 2001
766
Spinocerebellar ataxia type 6: channelopathy or glutamine repeat disorder? 38
11719255 2001
767
A case of hemiplegic migraine in childhood: transient unilateral hyperperfusion revealed by perfusion MR imaging and MR angiography. 38
11673182 2001
768
Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain. 38
11568319 2001
769
The pathophysiology of migraine. 38
12803669 2001
770
Mutant P/Q-type calcium channel electrophysiology and migraine. 38
11717812 2001
771
Neuromuscular transmission in migraine patients with prolonged aura. 38
11817265 2001
772
Ictal hemiparesis: differentiation from stroke. 38
11837478 2001
773
Hemiplegic migraine--downstream of a single-base change. 38
11439951 2001
774
Familial Hemiplegic Migraine 38
20301562 2001
775
Delayed cerebral edema and fatal coma after minor head trauma: role of the CACNA1A calcium channel subunit gene and relationship with familial hemiplegic migraine. 38
11409427 2001
776
Subclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements. 38
11357959 2001
777
Neuromuscular transmission in migraine: a single-fiber EMG study in clinical subgroups. 38
11320175 2001
778
Involvement of the CACNA1A gene containing region on 19p13 in migraine with and without aura. 38
11320173 2001
779
Neurology in ancient faces. 38
11254781 2001
780
Migraine variants. 38
11252150 2001
781
The impact of molecular biology on clinical neurology. 38
11406675 2001
782
Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2. 38
11179022 2001
783
Hemiplegic migraine during pregnancy: unusual magnetic resonance appearance with SPECT scan correlation. 38
11264693 2001
784
Relationship between migraine and cardiac and pulmonary right-to-left shunts. 38
11171291 2001
785
Missense CACNA1A mutation causing episodic ataxia type 2. 38
11176968 2001
786
[From gene to disease; from CACNA1A to migraine]. 38
11236374 2001
787
Sporadic hemiplegic migraine and Sturge-Weber syndrome. 38
11251712 2001
788
Disorders of membrane channels or channelopathies. 38
11137655 2001
789
Inherited ion channel disorders. 38
11216900 2000
790
Alternating hemiplegia of childhood: no mutations in the familial hemiplegic migraine CACNA1A gene. 38
11167897 2000
791
Molecular determinants of inactivation in voltage-gated Ca2+ channels. 38
11034614 2000
792
Evidence for allelic association of the dopamine beta-hydroxylase gene (DBH) with susceptibility to typical migraine. 38
11085595 2000
793
Familial Episodic Ataxias and Related Ion Channel Disorders. 38
11096768 2000
794
[The physiopathology of migraine]. 38
11072639 2000
795
[Calcium channels and migraine]. 38
11072642 2000
796
[Rare and atypical forms of migraine]. 38
11072645 2000
797
The scientific basis of migraine. 38
19667524 2000
798
Abnormal intracellular ca(2+)homeostasis and disease. 38
10942700 2000
799
Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine. 38
10891926 2000
800
Multimedia education in headache: the European Neurological Network. 38
10886323 2000
801
A new family with paroxysmal exercise induced dystonia and migraine: a clinical and genetic study. 38
10766892 2000
802
[Hemiplegic migraine. A series of 5 patients]. 38
10879007 2000
803
Abnormal transmitter release at neuromuscular junctions of mice carrying the tottering alpha(1A) Ca(2+) channel mutation. 38
10686170 2000
804
Three new familial hemiplegic migraine mutants affect P/Q-type Ca(2+) channel kinetics. 38
10734061 2000
805
Motor cortex excitability in patients with migraine with aura and hemiplegic migraine. 38
10817446 2000
806
Molecular genetics of migraine headaches: a review. 38
10817441 2000
807
A fine physical map of the CACNA1A gene region on 19p13.1-p13.2 chromosome. 38
10607897 2000
808
[Intracellular calcium: physiology and physiopathology]. 38
11196578 2000
809
[Family form of hemiplegic migraine]. 38
11195547 2000
810
[Rare and atypical forms of migraine]. 38
11139747 2000
811
Ion channels-related diseases. 38
11310970 2000
812
Impairment of neuromuscular transmission in a subgroup of migraine patients. 38
10612640 1999
813
[Coma associated with migraine]. 38
10637870 1999
814
The genetic basis of migraine: how much do we know? 38
10563232 1999
815
Voltage-gated ion channels and hereditary disease. 38
10508236 1999
816
Detection of a novel missense mutation and second recurrent mutation in the CACNA1A gene in individuals with EA-2 and FHM. 38
10987655 1999
817
Recurrent episodes of coma: an unusual phenotype of familial hemiplegic migraine with linkage to chromosome 1. 38
10569214 1999
818
[Familial hemiplegic migraine of childhood]. 38
10959293 1999
819
Genetic heterogeneity in Italian families with familial hemiplegic migraine. 38
10408532 1999
820
A new CACNA1A gene mutation in acetazolamide-responsive familial hemiplegic migraine and ataxia. 38
10408534 1999
821
High prevalence of CACNA1A truncations and broader clinical spectrum in episodic ataxia type 2. 38
10371528 1999
822
Calcium channelopathies in the central nervous system. 38
10395579 1999
823
Epilepsy and paroxysmal movement disorders in families: evidence for shared mechanisms. 38
10937138 1999
824
Association study of the CACN1A4 (SCA6) triplet repeat and schizophrenia. 38
10412193 1999
825
Genetic linkage analysis. 38
10369304 1999
826
Coincidence of familial hemiplegic migraine and hemicrania continua? A case report. 38
10403071 1999
827
Genetics of primary headaches. 38
10499169 1999
828
Mapping of hKCa3 to chromosome 1q21 and investigation of linkage of CAG repeat polymorphism to schizophrenia. 38
10395216 1999
829
[Current viewpoints on etiology and physiopathology of migraine]. 38
10354752 1999
830
The inheritance of migraine with aura estimated by means of structural equation modelling. 38
10204850 1999
831
Functional consequences of mutations in the human alpha1A calcium channel subunit linked to familial hemiplegic migraine. 38
10024348 1999
832
[Migraine with aphasia. Report of a family]. 38
10347736 1999
833
Familial hemiplegic migraine with cerebellar ataxia and paroxysmal psychosis. 38
10202246 1999
834
Recurrence of the T666M calcium channel CACNA1A gene mutation in familial hemiplegic migraine with progressive cerebellar ataxia. 38
9915947 1999
835
Search for mitochondrial DNA mutations in migraine subgroups. 38
10099855 1999
836
[Physiopathology of migraine]. 38
10029893 1998
837
Downbeat nystagmus in two siblings with spinocerebellar ataxia type 6 (SCA 6). 38
9849799 1998
838
Spinocerebellar ataxia type 6 with positional vertigo and acetazolamide responsive episodic ataxia. 38
9771787 1998
839
[Familial hemiplegic migraine]. 38
9748855 1998
840
Hemiplegia following general anaesthesia: an unusual presentation of migraine. 38
9785080 1998
841
Genetics and pathology of voltage-gated Ca2+ channels. 38
9690139 1998
842
Migraine, ataxia and epilepsy: a challenging spectrum of genetically determined calcium channelopathies. Dutch Migraine Genetics Research Group. 38
9781035 1998
843
Progressive facial hemiatrophy: abnormality of intracranial vasculature. 38
9633763 1998
844
Current status of genetic discoveries in migraine: familial hemiplegic migraine and beyond. 38
9642538 1998
845
Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner. 38
9614225 1998
846
[A sporadic case of episodic ataxia with nystagmus (EA-2)]. 38
9805992 1998
847
Familial typical migraine: linkage to chromosome 19p13 and evidence for genetic heterogeneity. 38
9596000 1998
848
Variable clinical expression of mutations in the P/Q-type calcium channel gene in familial hemiplegic migraine. Dutch Migraine Genetics Research Group. 38
9566402 1998
849
Familial hemiplegic migraine mutations change alpha1A Ca2+ channel kinetics. 38
9488686 1998
850
Familial hemiplegic migraine. 38
9550587 1998
851
Familial hemiplegic migraine with irreversible brain damage. 38
9550598 1998
852
Episodic ataxia and channelopathies. 38
9533553 1998
853
Familial hemiplegic migraine: involvement of a calcium neuronal channel. 38
9436352 1997
854
Mapping of a second locus for familial hemiplegic migraine to 1q21-q23 and evidence of further heterogeneity. 38
9403481 1997
855
A new locus for hemiplegic migraine maps to chromosome 1q31. 38
9371899 1997
856
Neurotology of migraine. 38
9439080 1997
857
[Ion channel diseases in neurology]. 38
9480290 1997
858
Familial hemiplegic migraine with crossed cerebellar diaschisis and unilateral meningeal enhancement. 38
9385760 1997
859
Episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6) due to CAG repeat expansion in the CACNA1A gene on chromosome 19p. 38
9302278 1997
860
Calcium channels in neurological disease. 38
9307247 1997
861
Phenotypic variability of CADASIL and novel morphologic findings. 38
9292694 1997
862
Wolff Award 1997. Involvement of a Ca2+ channel gene in familial hemiplegic migraine and migraine with and without aura. Dutch Migraine Genetics Research Group. 38
9329229 1997
863
Partial cosegregation of familial hemiplegic migraine and a benign familial infantile epileptic syndrome. 38
9579893 1997
864
The quest for migraine genes. 38
9229129 1997
865
Interictal cortical excitability to magnetic stimulation in familial hemiplegic migraine. 38
9153495 1997
866
Genetics of migraine. 38
9058396 1997
867
Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice. 38
9060410 1997
868
A family with hemiplegic migraine and focal seizures. 38
10728190 1997
869
The genetics of migraine. 38
24283816 1997
870
Familial hemiplegic migraine in the west of Scotland: a clinical and genetic study of seven families. 38
8971111 1996
871
Reversible cerebellar perfusion in familial hemiplegic migraine. 38
8918294 1996
872
Acetazolamide responsiveness in familial hemiplegic migraine. 38
8957029 1996
873
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. 38
8898206 1996
874
[Genetics of migraine]. 38
9036357 1996
875
Familial hemiplegic migraine in developmental age: report of two cases. 38
9177612 1996
876
Genetics of migraine and other headache. 38
8839611 1996
877
Familial hemiplegic migraine: a clinical comparison of families linked and unlinked to chromosome 19.DMG RG. 38
8734765 1996
878
Families linked and unlinked to chromosome 19 with familial hemiplegic migraine. 38
8734764 1996
879
Cerebral angiography complications link cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy to familial hemiplegic migraine. 38
8618700 1996
880
Identification of a key recombinant narrows the CADASIL gene region to 8 cM and argues against allelism of CADASIL and familial hemiplegic migraine. 38
8786108 1996
881
Familial migraine with vertigo and essential tremor. 38
8614512 1996
882
Familial hemiplegic migraine, nystagmus, and cerebellar atrophy. 38
8572654 1996
883
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, genetic homogeneity, and mapping of the locus within a 2-cM interval. 38
8554054 1996
884
A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene. Dutch Migraine Genetic Research Group. 38
9043864 1996
885
[CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)]. 38
9026542 1996
886
Case report: transient unilateral cerebral oedema in hemiplegic migraine: MR imaging and angiography. 38
8549055 1996
887
Common heredity of familial hemiplegic migraine and basilar artery migraine? 38
8706104 1995
888
Is familial hemiplegic migraine a hereditary form of basilar migraine? 38
8706110 1995
889
Familial hemiplegic migraine and autosomal dominant arteriopathy with leukoencephalopathy (CADASIL). 38
7486874 1995
890
Familial hemiplegic migraine locus on 19p13 is involved in the common forms of migraine with and without aura. 38
8530012 1995
891
Adult onset familial hemiplegic migraine. 38
7672961 1995
892
Hemiplegic migraine with CSF abnormalities. 38
7635725 1995
893
Monozygotic twins discordant for familial hemiplegic migraine. 38
7783896 1995
894
Abnormal brain and muscle energy metabolism shown by 31P-MRS in familial hemiplegic migraine. 38
7608738 1995
895
A gene for hereditary paroxysmal cerebellar ataxia maps to chromosome 19p. 38
7695228 1995
896
[Hemiplegic migraine]. 38
7899422 1995
897
Familial hemiplegic migraine versus migraine with prolonged aura: an uncertain diagnosis in a family report. 38
7824130 1995
898
Genetic heterogeneity of familial hemiplegic migraine. 38
7977376 1994
899
Familial migraine: exclusion of the susceptibility gene from the reported locus of familial hemiplegic migraine on 19p. 38
7851903 1994
900
[Biological modifications of CSF in hemiplegic migraine]. 38
7842135 1994
901
Familial hemiplegic migraine in The Netherlands. Dutch Migraine Genetics Research Group. 38
7988094 1994
902
Genetic heterogeneity of familial hemiplegic migraine. 38
7959770 1994
903
A prospective study of juvenile migraine with aura. 38
8026945 1994
904
Intracellular and plasma magnesium in familial hemiplegic migraine and migraine with and without aura. 38
8200020 1994
905
[Familial hemiplegic migraine. Localization of a responsible gene on chromosome 19]. 38
7878319 1994
906
Genetic approaches to common diseases. 38
7764464 1993
907
A gene for familial hemiplegic migraine maps to chromosome 19. 38
8220421 1993
908
The genetics of migraine without aura and migraine with aura. 38
8374938 1993
909
Hemiplegic migraine and moyamoya disease. 38
8322737 1993
910
[Sumatriptan (Imigran) to patients with hemiplegic migraine?]. 38
1329297 1992
911
Migraine and heredity. 38
1495812 1992
912
[Hemiplegic migraine complicated with coronary vasospasm]. 38
1628439 1992
913
Alternating hemiplegic migraine in childhood. 38
1839547 1991
914
Avascular necrosis associated with anticardiolipin antibodies. 38
1757948 1991
915
[Trauma-triggered migraine attacks. Review of the literature.]. 38
18415197 1991
916
Transcranial Doppler sonography in familial hemiplegic migraine. 38
2036667 1991
917
EEG in migraine: a review of the literature. 38
2055554 1991
918
[Nimodipine for the treatment of hemiplegic migraine. Description of a clinical case]. 38
2290534 1990
919
99mTc HM-PAO SPECT in pediatric migraine. 38
2272814 1990
920
Progressive hemifacial atrophy--a report of 2 cases. 38
2259953 1990
921
Hemiplegic migraine. 38
2391303 1990
922
Headaches in hospitalized cocaine users. 38
2714972 1989
923
Hemiplegic migraine following third molar extractions under intravenous sedation: report of a case. 38
2913255 1989
924
Juvenile alternating hemiplegic migraine. 38