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MCID: HMP003
MIFTS: 33

Hemopneumothorax

Categories: Blood diseases, Respiratory diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Hemopneumothorax

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MalaCards integrated aliases for Hemopneumothorax:

Name: Hemopneumothorax 12 43 15 17 71
Haemopneumothorax 12

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases Blood diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2718
MeSH 43 D006468
SNOMED-CT 67 16632002
ICD10 32 J94.2
UMLS 71 C0019077
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Summaries for Hemopneumothorax

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Disease Ontology : 12 A pneumothorax that is characterized by having air in the chest cavity and blood in the chest cavity.

MalaCards based summary : Hemopneumothorax, also known as haemopneumothorax, is related to spontaneous tension pneumothorax and cardiac tamponade. An important gene associated with Hemopneumothorax is NR0B2 (Nuclear Receptor Subfamily 0 Group B Member 2). The drugs Minocycline and Cefazolin have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and breast, and related phenotype is homeostasis/metabolism.

Wikipedia : 74 Hemopneumothorax, or haemopneumothorax is the condition of having air in the chest cavity (pneumothorax)... more...

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Related Diseases for Hemopneumothorax

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Diseases related to Hemopneumothorax via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 spontaneous tension pneumothorax 30.5 NR0B2 HCCS
2 cardiac tamponade 30.2 F3 F2
3 respiratory failure 28.9 SFTPD F3 F2
4 pneumothorax 10.9
5 pneumothorax, primary spontaneous 10.7
6 virus-associated trichodysplasia spinulosa 10.6
7 pleural empyema 10.4
8 pulmonary edema 10.4
9 endometriosis 10.3
10 angiosarcoma 10.2
11 paralytic ileus 10.2 F2 ERVMER34-1
12 common bile duct disease 10.2 F2 ERVMER34-1
13 choledocholithiasis 10.2 F2 ERVMER34-1
14 pleural disease 10.1
15 hemangioma 10.1
16 lung disease 10.1
17 angiosarcoma of the scalp 10.1
18 catamenial pneumothorax 10.1
19 cryptorchidism, unilateral or bilateral 10.1
20 esophageal atresia 10.1
21 hereditary hemorrhagic telangiectasia 10.1
22 telangiectasis 10.1
23 exostosis 10.1
24 achenbach syndrome 10.1 F3 F2
25 fournier gangrene 10.1 F3 F2
26 synovial angioma 10.1 F3 F2
27 renal pelvis squamous cell carcinoma 10.1 F3 F2
28 papillary adenofibroma 10.0 F3 F2
29 blue toe syndrome 10.0 F3 F2
30 emphysematous cholecystitis 10.0 F3 F2
31 femoral neuropathy 10.0 F3 F2
32 lateral sinus thrombosis 10.0 F3 F2
33 giant hemangioma 10.0 F3 F2
34 dic in newborn 10.0 F3 F2
35 waterhouse-friderichsen syndrome 10.0 F3 F2
36 cavernous sinus thrombosis 10.0 F3 F2
37 lemierre's syndrome 10.0 F3 F2
38 gastric hemangioma 10.0 F3 F2
39 hepatic infarction 10.0 F3 F2
40 qualitative platelet defect 10.0 F3 F2
41 ankylosing spondylitis 1 10.0 F3 F2
42 marantic endocarditis 10.0 F3 F2
43 intracranial sinus thrombosis 10.0 F3 F2
44 cerebral sinovenous thrombosis 10.0 F3 F2
45 prothrombin deficiency 10.0 F3 F2
46 sagittal sinus thrombosis 10.0 F3 F2
47 mediastinitis 10.0 F3 F2
48 cerebral falx meningioma 10.0 F3 F2
49 intracranial hypotension 10.0 F3 F2
50 intracranial embolism 10.0 F3 F2

Graphical network of the top 20 diseases related to Hemopneumothorax:



Diseases related to Hemopneumothorax
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Symptoms & Phenotypes for Hemopneumothorax

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MGI Mouse Phenotypes related to Hemopneumothorax:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 DPF2 F2 F3 FAN1 HCCS LARP6
Sources

Drugs & Therapeutics for Hemopneumothorax

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Drugs for Hemopneumothorax (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
2
Cefazolin Approved Phase 2, Phase 3 25953-19-9 656510 33255
3
Clindamycin Approved, Vet_approved Phase 2, Phase 3 18323-44-9 29029
4 Clindamycin phosphate Phase 2, Phase 3
5 Anti-Bacterial Agents Phase 2, Phase 3
6 penicillins Phase 2, Phase 3
7 Clindamycin palmitate Phase 2, Phase 3
8 Lactams Phase 2, Phase 3
9 Anti-Infective Agents Phase 2, Phase 3
10 Antibiotics, Antitubercular Phase 2, Phase 3
11
Sufentanil Approved, Investigational 56030-54-7 41693
12
Ropivacaine Approved 84057-95-4 71273 175805
13
Tropisetron Approved, Investigational 89565-68-4, 105826-92-4 5595
14 Pharmaceutical Solutions

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective and Randomized Study Comparing 14 F Pigtail Catheter to Traditional 32-36F Chest Tube in the Management of Traumatic Hemothorax and Hemopneumothorax Unknown status NCT02553434 Phase 3
2 Phase III Study of Additional Minocycline Pleurodesis After Video-Assisted Thoracoscopic Surgery for Primary Spontaneous Pneumothorax Unknown status NCT00154895 Phase 3 intrapleural minocycline instillation
3 The Role of Antibiotics in the Reduction of Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax: A Prospective, Double-Blinded Study Completed NCT01127880 Phase 2, Phase 3 Ancef or Clindamycin;Placebo
4 Efficacy of Negative Pleural Suction in Tube Thoracostomy for Patients With Penetrating and/or Blunt Chest Trauma: a Randomized Clinical Trial Completed NCT01864577
5 The Small (14F) Percutaneous Catheter vs. Large (28-40F) Open Chest Tube for Traumatic Hemothorax (P-CAT): A Multi-center Randomized Clinical Trial Recruiting NCT03546764
6 A Randomized Controlled Trial Comparing Quadratus Lumborum Block and Paravertebral Block for Postoperative Analgesia in Laparoscopic Hepatectomy and Open Hepatectomy Recruiting NCT03540537
7 Prospective Evaluation of 14F Thal Tube vs 28 French Chest Tube for Hemothorax and Use of Maximum Barrier Precautions Enrolling by invitation NCT03167723
8 Application Study of 12G Pigtail Catheter Used for Post-operative Drainage After Thoracoscopic Surgery for Mediastinal Nodes Not yet recruiting NCT03743389

Search NIH Clinical Center for Hemopneumothorax

Cochrane evidence based reviews: hemopneumothorax

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Genetic Tests for Hemopneumothorax

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Anatomical Context for Hemopneumothorax

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MalaCards organs/tissues related to Hemopneumothorax:

40
Lung, Liver, Breast, Spinal Cord, Heart, Bone Marrow, Bone
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Publications for Hemopneumothorax

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Articles related to Hemopneumothorax:

(show top 50) (show all 688)
# Title Authors PMID Year
1
A rare cause of recurrent hemopneumothorax. 61
30722765 2020
2
Predictors of blunt abdominal aortic injury in trauma patients and mortality analysis. 61
31699513 2020
3
Performance of pre-hospital evaluations in ruling out invasive chest stab wounds. 61
32370808 2020
4
Re: Haemopneumothorax subsequent to acupuncture: a rural centre experience. 61
32339422 2020
5
Response to Re: Haemopneumothorax subsequent to acupuncture: a rural centre experience. 61
32339436 2020
6
New perspectives for a huge traumatic pneumatocele treatment in a young adult. 61
32089840 2020
7
Tension Hemopneumothorax in the Setting of Mechanical CPR during Prehospital Cardiac Arrest. 61
32208039 2020
8
Hemopneumothorax After Trigger Point Injection for Fibromyalgia. 61
31221937 2020
9
Post-traumatic left anterior descending artery dissection. 61
32139211 2020
10
How emergency physicians choose chest tube size for traumatic pneumothorax or hemothorax: a comparison between 28Fr and smaller tube. 61
32273633 2020
11
Catamenial pneumothorax recurrence due to endometriosis. 61
32190546 2020
12
Spontaneous Hemopneumothorax: A Rare Cause of Unexplained Hemodynamic Instability in a Young Patient. 61
32047694 2020
13
Hemothorax resulting from an initially masked aortic perforation caused by penetration of the sharp edge of a fractured rib: A case report. 61
32109767 2020
14
[Early Sternum Fixation with a Locking Plate for Traumatic Sternal Fracture]. 61
31879383 2019
15
Determining the clinical significance of the Chest Wall Injury Society taxonomy for multiple rib fractures. 61
31688826 2019
16
Image-guided interstitial high-dose-rate brachytherapy for dose escalation in the radiotherapy treatment of locally advanced lung cancer: A single-institute experience. 61
31500935 2019
17
Displaced Medial-End Clavicle Fractures Treated with Locking Plate Osteosynthesis. 61
31596837 2019
18
Pneumocephalus and pneumorachis after blunt chest trauma without spinal fractures: a case report. 61
31651338 2019
19
Factors affecting mortality in traumatic diaphragm ruptures. 61
31701506 2019
20
Haemopneumothorax subsequent to acupuncture: a rural centre experience. 61
31625261 2019
21
Traumatic aorto-pulmonary artery fistula: a case report. 61
31660493 2019
22
Minimally invasive surgical management of penetrating chest injury from kinetic impact bean bag projectile. 61
31338405 2019
23
Needlescopic Video-Assisted Thoracic Bilateral T4 Sympathicotomy for the Treatment of Primary Palmar Hyperhidrosis: An Analysis of 200 Cases. 61
29715706 2019
24
Accidental neck and chest penetration by a metal sliver derived from an axe for wood chopping: a case report. 61
31420009 2019
25
Anesthetic management of tracheal laceration from traumatic dislocation of the first rib: a case report and literature of the review. 61
31399024 2019
26
[Spontaneous haemopneumothorax: A case report]. 61
30573228 2019
27
Assessment of related surgical complications of minimally invasive retropleural approach to the thoraco-lumbar spine. 61
30606644 2019
28
A case report: Veno-venous extracorporeal membrane oxygenation for severe blunt thoracic trauma. 61
31060587 2019
29
Treatment of open chest rib fractures with the matrix rib internal fixation system: A case report. 61
31096506 2019
30
National risk factors for blunt cardiac injury: Hemopneumothorax is the strongest predictor. 61
30060913 2019
31
Acute severe asthma complicated with tension pneumothorax and hemopneumothorax. 61
31334052 2019
32
Five years of prolonged field care: prehospital challenges during recent French military operations. 61
30980759 2019
33
A paediatric case of severe tracheobronchial injury successfully treated surgically after early CT diagnosis and ECMO safely performed in the hybrid emergency room. 61
31014372 2019
34
[Birt-Hogg-Dubé Syndrome Incidentally Found at Surgery for Idiopathic Hemopneumothorax;Report of a Case]. 61
30923304 2019
35
Chest drain and thoracotomy for chest trauma. 61
30906584 2019
36
Bilateral catamenial hemopneumothorax: Diagnostic & management challenges. 61
31398668 2019
37
Video-tube thoracostomy in trauma resuscitation: A pilot study. 61
30143233 2019
38
Presumptive antibiotics in tube thoracostomy for traumatic hemopneumothorax: a prospective, Multicenter American Association for the Surgery of Trauma Study. 61
31799417 2019
39
Efficacy of uniportal video assisted thoracoscopic surgery in management of primary spontaneous hemopneumothorax. 61
30685628 2019
40
Usefulness of Cibenzoline Stress Echocardiography to Determine Severity of Aortic Stenosis in a Patient with Combined Left Ventricular Outflow Tract Obstruction and Aortic Stenosis. 61
31548489 2019
41
Current strategy for hollow viscus injury with active bleeding: A case report. 61
30728979 2019
42
[The features and treatment of Xixia "May 17th" explosion accident]. 61
30592957 2018
43
[Clinical Assessment of Spontaneous Hemopneumothorax]. 61
30449865 2018
44
Severe haemophilia A in a neonate presenting as haemopneumothorax after tracheo-oesophageal fistula-oesophageal atresia repair. 61
30413439 2018
45
Surgical versus conservative therapy for multiple rib fractures: a retrospective analysis. 61
30596069 2018
46
Gunshot Injury of Head and Neck Region with an Atypical Bullet Trajectory: The Importance of Whole Body Computed Tomography Scan. 61
30173703 2018
47
Heparin-free veno-venous ECMO applied to a patient with severe lung contusion and hypovolemic shock due to trauma. 61
30394486 2018
48
Spinal Gunshot Wounds: Pattern and Associated Lesions in Civilians. 61
30060372 2018
49
14-French Pigtail Catheters for Traumatic Hemothorax/Hemopneumothorax: Size Does Not Matter: Reply. 61
29423739 2018
50
14-French Pigtail Catheters for Traumatic Hemothorax/Hemopneumothorax: Size Does Not Matter. 61
29282512 2018
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Variations for Hemopneumothorax

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Expression for Hemopneumothorax

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Search GEO for disease gene expression data for Hemopneumothorax.
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Pathways for Hemopneumothorax

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GO Terms for Hemopneumothorax

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Biological processes related to Hemopneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemostasis GO:0007599 8.96 F3 F2
2 positive regulation of collagen biosynthetic process GO:0032967 8.62 LARP6 F2

Molecular functions related to Hemopneumothorax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 8.62 SFTPD F2
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Sources for Hemopneumothorax

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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