HFRS
MCID: HMR004
MIFTS: 57

Hemorrhagic Fever with Renal Syndrome (HFRS)

Categories: Infectious diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Hemorrhagic Fever with Renal Syndrome

MalaCards integrated aliases for Hemorrhagic Fever with Renal Syndrome:

Name: Hemorrhagic Fever with Renal Syndrome 12 77 45 15 17 74
Hantavirosis 60 74
Hemorrhagic Fever-Renal Syndrome 60
Hemorrhagic Nephrosonephritis 12
Hemorrhagic Fever, Russian 12
Puumala Virus Nephropathy 12
Hantavirus Fever 60
Hfrs 12

Characteristics:

Orphanet epidemiological data:

60
hemorrhagic fever-renal syndrome
Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 60  
Rare infectious diseases


Summaries for Hemorrhagic Fever with Renal Syndrome

Disease Ontology : 12 A viral infectious disease that is a hemorrhagic fever, located in kidney, has material basis in Hantaan virus, has material basis in Dobrava-Belgrade virus, has material basis in Seoul virus, or has material basis in Puumala virus, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom hemorrhagic features, has symptom proteinuria, and has symptom renal failure.

MalaCards based summary : Hemorrhagic Fever with Renal Syndrome, also known as hantavirosis, is related to hemorrhagic fever and scrub typhus. An important gene associated with Hemorrhagic Fever with Renal Syndrome is TNF (Tumor Necrosis Factor), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Antibodies, Blocking and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include kidney, t cells and testes, and related phenotypes are fever and fatigue

Wikipedia : 77 Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a group of clinically similar illnesses... more...

Related Diseases for Hemorrhagic Fever with Renal Syndrome

Diseases related to Hemorrhagic Fever with Renal Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 296)
# Related Disease Score Top Affiliating Genes
1 hemorrhagic fever 31.1 ALB B2M GPT HLA-DRB1 IL6 ITGB3
2 scrub typhus 30.4 CRP GPT TNF
3 acute pancreatitis 30.2 CRP CXCL8 IL6
4 leptospirosis 29.9 CRP CXCL8 IL6 TNF
5 hemophagocytic lymphohistiocytosis 29.9 B2M CXCL8 TNF
6 acute respiratory distress syndrome 29.7 CXCL8 IL6 TNF
7 myocardial infarction 29.6 ALB CRP IL6 ITGB3 TNF
8 chlamydia 29.5 CRP CXCL8 IL6 TNF
9 myeloma, multiple 29.1 ALB B2M CRP CXCL8 IL6 TNF
10 korean hemorrhagic fever 12.1
11 danubian endemic familial nephropathy 11.5
12 hantavirus pulmonary syndrome 11.5
13 pancreatitis, hereditary 11.2
14 balkan hemorrhagic fever 11.2
15 adult dermatomyositis 10.5 GPT TNF
16 aids dementia complex 10.5 B2M TNF
17 extramedullary plasmacytoma 10.5 B2M IL6
18 retinitis pigmentosa 55 10.5 IL6 TNF
19 angioimmunoblastic lymphadenopathy with dysproteinemia 10.5 IL6 TNF
20 critical limb ischemia 10.5 IL6 TNF
21 juvenile ankylosing spondylitis 10.5 IL6 TNF
22 glossitis 10.5 IL6 TNF
23 laryngitis 10.5 IL6 TNF
24 null-cell leukemia 10.5 IL6 TNF
25 autoimmune myocarditis 10.5 IL6 TNF
26 leukomalacia 10.5 IL6 TNF
27 cardiogenic shock 10.5 IL6 TNF
28 pyomyositis 10.5 CRP GPT
29 salpingitis 10.5 CRP TNF
30 neutrophilia, hereditary 10.4 CRP IL6
31 sudden sensorineural hearing loss 10.4 IL6 ITGB3
32 acute cholangitis 10.4 CRP IL6
33 cold agglutinin disease 10.4 CRP IL6
34 cryopyrin-associated periodic syndrome 10.4 CRP IL6
35 uremic pruritus 10.4 CRP IL6
36 beryllium disease 10.4 HLA-DRB1 TNF
37 microscopic polyangiitis 10.4 HLA-DRB1 TNF
38 chronic beryllium disease 10.4 HLA-DRB1 TNF
39 anca-associated vasculitis 10.4 HLA-DRB1 IL6
40 hepatic coma 10.4 ALB GPT
41 kwashiorkor 10.4 ALB GPT
42 hepatic tuberculosis 10.4 ALB GPT
43 macrophage activation syndrome 10.4 CD163 TNF
44 immunodeficiency 43 10.4 ALB B2M
45 diffuse glomerulonephritis 10.4 ALB B2M
46 burns 10.4 ALB TNF
47 orthostatic proteinuria 10.4 ALB B2M
48 chronic graft versus host disease 10.4 ALB TNF
49 abdominal tuberculosis 10.4 ALB CRP
50 gastrointestinal tuberculosis 10.4 ALB CRP

Graphical network of the top 20 diseases related to Hemorrhagic Fever with Renal Syndrome:



Diseases related to Hemorrhagic Fever with Renal Syndrome

Symptoms & Phenotypes for Hemorrhagic Fever with Renal Syndrome

Human phenotypes related to Hemorrhagic Fever with Renal Syndrome:

60 33 (show all 33)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 60 33 hallmark (90%) Very frequent (99-80%) HP:0001945
2 fatigue 60 33 hallmark (90%) Very frequent (99-80%) HP:0012378
3 respiratory insufficiency 60 33 frequent (33%) Frequent (79-30%) HP:0002093
4 renal insufficiency 60 33 frequent (33%) Frequent (79-30%) HP:0000083
5 proteinuria 60 33 frequent (33%) Frequent (79-30%) HP:0000093
6 photophobia 60 33 frequent (33%) Frequent (79-30%) HP:0000613
7 arthralgia 60 33 frequent (33%) Frequent (79-30%) HP:0002829
8 abdominal pain 60 33 frequent (33%) Frequent (79-30%) HP:0002027
9 thrombocytopenia 60 33 frequent (33%) Frequent (79-30%) HP:0001873
10 tubulointerstitial abnormality 60 33 frequent (33%) Frequent (79-30%) HP:0001969
11 migraine 60 33 frequent (33%) Frequent (79-30%) HP:0002076
12 myalgia 60 33 frequent (33%) Frequent (79-30%) HP:0003326
13 atelectasis 60 33 frequent (33%) Frequent (79-30%) HP:0100750
14 leukocytosis 60 33 frequent (33%) Frequent (79-30%) HP:0001974
15 conjunctivitis 60 33 frequent (33%) Frequent (79-30%) HP:0000509
16 pleural effusion 60 33 frequent (33%) Frequent (79-30%) HP:0002202
17 pulmonary infiltrates 60 33 frequent (33%) Frequent (79-30%) HP:0002113
18 oliguria 60 33 frequent (33%) Frequent (79-30%) HP:0100520
19 hypoproteinemia 60 33 frequent (33%) Frequent (79-30%) HP:0003075
20 subconjunctival hemorrhage 60 33 frequent (33%) Frequent (79-30%) HP:0011896
21 elevated hepatic transaminase 33 frequent (33%) HP:0002910
22 hypertension 60 33 occasional (7.5%) Occasional (29-5%) HP:0000822
23 hypotension 60 33 occasional (7.5%) Occasional (29-5%) HP:0002615
24 arrhythmia 60 33 occasional (7.5%) Occasional (29-5%) HP:0011675
25 myopia 60 33 occasional (7.5%) Occasional (29-5%) HP:0000545
26 amaurosis fugax 60 33 occasional (7.5%) Occasional (29-5%) HP:0100576
27 abnormal myocardium morphology 60 33 occasional (7.5%) Occasional (29-5%) HP:0001637
28 hemoptysis 60 33 occasional (7.5%) Occasional (29-5%) HP:0002105
29 gastrointestinal hemorrhage 60 33 occasional (7.5%) Occasional (29-5%) HP:0002239
30 intracranial hemorrhage 60 33 occasional (7.5%) Occasional (29-5%) HP:0002170
31 abnormal pericardium morphology 60 33 occasional (7.5%) Occasional (29-5%) HP:0001697
32 elevated hepatic transaminases 60 Frequent (79-30%)
33 abnormality of the renal tubule 60 Frequent (79-30%)

Drugs & Therapeutics for Hemorrhagic Fever with Renal Syndrome

Drugs for Hemorrhagic Fever with Renal Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies, Blocking Phase 3
2 Immunoglobulins Phase 3
3 Vaccines Phase 3,Phase 2,Phase 1
4 Antibodies Phase 3
5
Epinephrine Approved, Vet_approved Phase 2,Phase 1 51-43-4 5816
6
Racepinephrine Approved Phase 2,Phase 1 329-65-7 838
7
Ribavirin Approved Phase 2 36791-04-5 37542
8 Epinephryl borate Phase 2,Phase 1
9 Immunologic Factors Phase 2,Phase 1
10 Antiviral Agents Phase 2
11 Anti-Infective Agents Phase 2
12 Antimetabolites Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study to Evalutate Long-term Immunity of Hantavax in High Risk Population of HFRS Completed NCT02360514 Phase 3 Hantavax injection
2 Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic Fever Active, not recruiting NCT02116205 Phase 2
3 Ribavirin for Hemorrhagic Fever With Renal Syndrome Enrolling by invitation NCT00623168 Phase 2 Ribavirin
4 Ribavirin for Hemorrhagic Fever With Renal Syndrome in Germany Withdrawn NCT00868946 Phase 2 Virazole (Ribavirin)
5 Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA Vaccines Completed NCT01502345 Phase 1
6 Diagnostic of Puumala Virus Infection in France Recruiting NCT02455375

Search NIH Clinical Center for Hemorrhagic Fever with Renal Syndrome

Cochrane evidence based reviews: hemorrhagic fever with renal syndrome

Genetic Tests for Hemorrhagic Fever with Renal Syndrome

Anatomical Context for Hemorrhagic Fever with Renal Syndrome

MalaCards organs/tissues related to Hemorrhagic Fever with Renal Syndrome:

42
Kidney, T Cells, Testes, Endothelial, Neutrophil, B Cells, Heart

Publications for Hemorrhagic Fever with Renal Syndrome

Articles related to Hemorrhagic Fever with Renal Syndrome:

(show top 50) (show all 426)
# Title Authors Year
1
Hemorrhagic Fever with Renal Syndrome as a Cause of Acute Diarrhea. ( 30915955 )
2019
2
Dentin matrix protein 1 correlates with the severity of hemorrhagic fever with renal syndrome and promotes hyper-permeability of endothelial cells infected by Hantaan virus. ( 30735719 )
2019
3
Epidemiologic study on changes in occurrence of hemorrhagic fever with renal syndrome in Republic of Korea for 17 years according to age group: 2001-2017. ( 30760218 )
2019
4
Effects of climate factors on hemorrhagic fever with renal syndrome in Changchun, 2013 to 2017. ( 30817583 )
2019
5
Recent Increase of Human Granulocytic Anaplasmosis and Co-Infection with Scrub Typhus or Korean Hemorrhagic Fever with Renal Syndrome in Korea. ( 30914905 )
2019
6
Hemorrhagic fever with renal syndrome accompanied by panhypopituitarism and central diabetes insipidus: a case report. ( 29508304 )
2018
7
Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome. ( 29450213 )
2018
8
Impact of meteorological factors on hemorrhagic fever with renal syndrome in 19 cities in China, 2005-2014. ( 29913587 )
2018
9
Meteorological factors and risk of hemorrhagic fever with renal syndrome in Guangzhou, southern China, 2006-2015. ( 29949572 )
2018
10
Delayed Interferon Type 1-Induced Antiviral State Is a Potential Factor for Hemorrhagic Fever With Renal Syndrome Severity. ( 29281106 )
2018
11
Mapping the epidemic changes and risks of hemorrhagic fever with renal syndrome in Shaanxi Province, China, 2005-2016. ( 29335595 )
2018
12
Absence of a Seasonal Variation of Hemorrhagic Fever with Renal Syndrome in Yeoncheon Compared to Nationwide Korea. ( 29968979 )
2018
13
Protective effectiveness of inactivated hantavirus vaccine against hemorrhagic fever with renal syndrome. ( 29373686 )
2018
14
Author Correction: Mapping the epidemic changes and risks of hemorrhagic fever with renal syndrome in Shaanxi Province, China, 2005-2016. ( 29651028 )
2018
15
Guillain-Barre syndrome associated with hemorrhagic fever with renal syndrome in China: a case report. ( 29587642 )
2018
16
Landscape and rodent community composition are associated with risk of hemorrhagic fever with renal syndrome in two cities in China, 2006-2013. ( 29329512 )
2018
17
Study on expression of plasma sCD138 in patients with hemorrhagic fever with renal syndrome. ( 29490629 )
2018
18
A Nonfatal Case of Dobrava Hantavirus Hemorrhagic Fever with Renal Syndrome Combined with Hantavirus Cardiopulmonary Syndrome. ( 29563720 )
2018
19
High Serum Procalcitonin Concentrations in Patients With Hemorrhagic Fever With Renal Syndrome Caused by Hantaan Virus. ( 29868489 )
2018
20
Sequential assessment of clinical and laboratory parameters in patients with hemorrhagic fever with renal syndrome. ( 29791494 )
2018
21
Involvement of CD8<sup>+</sup> T cells in the development of renal hemorrhage in a mouse model of hemorrhagic fever with renal syndrome. ( 29488118 )
2018
22
Relationship between circulating vascular endothelial growth factor and its soluble receptor in patients with hemorrhagic fever with renal syndrome. ( 29765019 )
2018
23
Expression of CD206 and CD163 on intermediate CD14<sup>++</sup>CD16<sup>+</sup> monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity. ( 29857122 )
2018
24
Risk of Venous Thromboembolism Following Hemorrhagic Fever With Renal Syndrome: A Self-controlled Case Series Study. ( 29020303 )
2018
25
Platelet Distribution Width at First Day of Hospital Admission in Patients with Hemorrhagic Fever with Renal Syndrome Caused by Hantaan Virus May Predict Disease Severity and Critical Patients' Survival. ( 30018676 )
2018
26
Spatiotemporal analysis and forecasting model of hemorrhagic fever with renal syndrome in mainland China. ( 30078384 )
2018
27
Two cases of imported hemorrhagic fever with renal syndrome and systematic review of literature. ( 30114480 )
2018
28
Spatiotemporal patterns of hemorrhagic fever with renal syndrome in Hebei Province, China, 2001-2016. ( 30133872 )
2018
29
Environmental Determinants of Hemorrhagic Fever with Renal Syndrome in High-Risk Counties in China: A Time Series Analysis (2002-2012). ( 30226151 )
2018
30
There is Still Seasonal Variation of Hemorrhagic Fever with Renal Syndrome in Gyeonggi Province. ( 30270589 )
2018
31
Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells. ( 30283445 )
2018
32
Spatial heterogeneity of hemorrhagic fever with renal syndrome is driven by environmental factors and rodent community composition. ( 30356291 )
2018
33
A new Seasonal Difference Space-Time Autoregressive Integrated Moving Average (SD-STARIMA) model and spatiotemporal trend prediction analysis for Hemorrhagic Fever with Renal Syndrome (HFRS). ( 30475830 )
2018
34
Effectiveness of inactivated hantavirus vaccine on the disease severity of hemorrhagic fever with renal syndrome. ( 30619692 )
2018
35
Hemorrhagic fever with renal syndrome (HFRS) in Poland ( 30810003 )
2018
36
Meteorological factors affect the epidemiology of hemorrhagic fever with renal syndrome via altering the breeding and hantavirus-carrying states of rodents and mites: a 9 years' longitudinal study. ( 29184158 )
2017
37
Performance assessment of the SAPS II and SOFA scoring systems in Hanta virus Hemorrhagic Fever with Renal Syndrome. ( 28804005 )
2017
38
Analysis of hemorrhagic fever with renal syndrome and its pathogenic gene sequence based on geographic information system. ( 28685549 )
2017
39
Hantavirus retinitis and concurrent hemorrhagic fever with renal syndrome. ( 28237172 )
2017
40
Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/K<sup>b</sup>Transgenic Mice May Associate with the Severity of Hemorrhagic Fever with Renal Syndrome. ( 29312318 )
2017
41
Serum Cytokine Profiles Differentiating Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome. ( 28572804 )
2017
42
Hemorrhagic fever with renal syndrome in Albania. Focus on predictors of acute kidney injury in HFRS. ( 28411480 )
2017
43
Lack of association between integrin I+vI^3 gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China. ( 28190175 )
2017
44
Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome. ( 28141833 )
2017
45
Hemorrhagic fever with renal syndrome caused by Hantaan virus infection in four pregnant Chinese women. ( 28504470 )
2017
46
The influence of climatic factors on the development of hemorrhagic fever with renal syndrome and leptospirosis during the peak season in Korea: an ecologic study. ( 28592316 )
2017
47
[REVIEW OF EPIDEMIOLOGIC SITUATION ON HEMORRHAGIC FEVER WITH RENAL SYNDROME (HERS) IN RUSSIAN FEDERATION IN 1990 - 2015]. ( 30695531 )
2017
48
Prevalence of hemorrhagic fever with renal syndrome in Yiyuan County, China, 2005-2014. ( 26852019 )
2016
49
Cytokine response to Hantaan virus infection in patients with hemorrhagic fever with renal syndrome. ( 27943332 )
2016
50
Clinical characterization of two severe cases of hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses Puumala and Dobrava-Belgrade genotype Sochi. ( 27842513 )
2016

Variations for Hemorrhagic Fever with Renal Syndrome

Expression for Hemorrhagic Fever with Renal Syndrome

Search GEO for disease gene expression data for Hemorrhagic Fever with Renal Syndrome.

Pathways for Hemorrhagic Fever with Renal Syndrome

Pathways related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.83 B2M CD55 CRP CXCL8 HLA-B HLA-DRB1
2
Show member pathways
13.11 B2M CXCL8 HLA-B HLA-DRB1 IL6 ITGB3
3
Show member pathways
12.85 HLA-B IL6 ITGB3 TNF VTN
4
Show member pathways
12.7 B2M CXCL8 HLA-B IL6 ITGB3 TNF
5
Show member pathways
12.44 B2M CD55 CXCL8 HLA-B HLA-DRB1 IL6
6
Show member pathways
12.43 CXCL8 HLA-B HLA-DRB1 IL6 TNF
7 12.23 HLA-B HLA-DRB1 IL6 TNF
8
Show member pathways
12.19 ALB CRP IL6 TNF
9
Show member pathways
12.14 CXCL8 HLA-B IL6 TNF
10
Show member pathways
11.98 CD55 CRP VTN
11
Show member pathways
11.95 CD55 CRP VTN
12 11.89 CXCL8 IL6 TNF
13 11.87 CXCL8 IL6 TNF
14 11.82 CXCL8 IL6 VTN
15 11.79 CXCL8 IL6 TNF
16 11.76 CXCL8 IL6 TNF
17 11.73 CD163 IL6 ITGB3 TNF
18 11.66 CXCL8 IL6 TNF
19 11.63 CD163 IL6 TNF
20 11.58 CXCL8 HLA-DRB1 IL6 TNF
21 11.55 CXCL8 IL6 TNF
22
Show member pathways
11.54 CXCL8 IL6 TNF
23 11.44 CXCL8 IL6 TNF
24 11.41 CD163 IL6 ITGB3 TNF
25 11.38 CXCL8 IL6 TNF
26 11.36 CXCL8 IL6 TNF
27 11.34 CD55 HLA-DRB1 IL6 ITGB3 TNF
28 11.33 IL6 TNF VTN
29 11.04 HLA-DRB1 IL6 TNF
30 10.2 CRP CXCL8 IL6 TNF

GO Terms for Hemorrhagic Fever with Renal Syndrome

Cellular components related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.92 ALB B2M CD55 GPT HLA-B HLA-DRB1
2 extracellular region GO:0005576 9.81 ALB B2M CD163 CD55 CRP CXCL8
3 external side of plasma membrane GO:0009897 9.73 B2M CD163 HLA-DRB1 TNF
4 ER to Golgi transport vesicle membrane GO:0012507 9.54 B2M HLA-B HLA-DRB1
5 cell surface GO:0009986 9.43 B2M CD55 HLA-B HLA-DRB1 ITGB3 TNF
6 MHC class I protein complex GO:0042612 9.4 B2M HLA-B
7 extracellular space GO:0005615 9.28 ALB B2M CRP CXCL8 GPT IL6
8 alphav-beta3 integrin-vitronectin complex GO:0071062 9.26 ITGB3 VTN

Biological processes related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.77 CD163 CRP CXCL8 IL6 TNF
2 defense response to Gram-positive bacterium GO:0050830 9.67 CRP IL6 TNF
3 viral entry into host cell GO:0046718 9.65 CD55 HLA-DRB1 ITGB3
4 interferon-gamma-mediated signaling pathway GO:0060333 9.61 B2M HLA-B HLA-DRB1
5 positive regulation of chemokine production GO:0032722 9.57 IL6 TNF
6 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.56 ITGB3 VTN
7 immune response GO:0006955 9.56 B2M CXCL8 HLA-B HLA-DRB1 IL6 SEMA4D
8 embryonic digestive tract development GO:0048566 9.55 CXCL8 TNF
9 positive regulation of glial cell proliferation GO:0060252 9.54 IL6 TNF
10 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.52 CRP ITGB3
11 response to molecule of bacterial origin GO:0002237 9.51 B2M CXCL8
12 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.46 B2M HLA-B
13 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.46 IL6 ITGB3 SEMA4D VTN
14 acute-phase response GO:0006953 9.43 CD163 CRP IL6
15 positive regulation of neuroinflammatory response GO:0150078 9.4 IL6 TNF
16 negative regulation of alkaline phosphatase activity GO:0010693 9.32 SEMA4D TNF
17 negative regulation of lipid storage GO:0010888 8.92 CRP IL6 ITGB3 TNF

Molecular functions related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.43 ALB B2M CRP ITGB3 TNF VTN
2 virus receptor activity GO:0001618 8.8 CD55 HLA-DRB1 ITGB3

Sources for Hemorrhagic Fever with Renal Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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