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MCID: HMR005
MIFTS: 54

Hemorrhoid

Categories: Cardiovascular diseases, Gastrointestinal diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Hemorrhoid

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MalaCards integrated aliases for Hemorrhoid:

Name: Hemorrhoid 12 76 15
Hemorrhoids 43 44 73
Hemorrhoidal Disease 12
Rectal Diseases 73

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Gastrointestinal diseases Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:9746
ICD9CM 35 455
MeSH 44 D006484
NCIt 50 C26792
SNOMED-CT 68 70153002
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Summaries for Hemorrhoid

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MedlinePlus : 43 Hemorrhoids are swollen, inflamed veins around the anus or lower rectum. They are either inside the anus or under the skin around the anus. They often result from straining to have a bowel movement. Other factors include pregnancy, aging and chronic constipation or diarrhea. Hemorrhoids are very common in both men and women. About half of all people have hemorrhoids by age 50. The most common symptom of hemorrhoids inside the anus is bright red blood covering the stool, on toilet paper or in the toilet bowl. Symptoms usually go away within a few days. If you have rectal bleeding you should see a doctor. You need to make sure bleeding is not from a more serious condition such as colorectal or anal cancer. Treatment may include warm baths and a cream or other medicine. If you have large hemorrhoids, you may need surgery and other treatments. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Hemorrhoid, also known as hemorrhoids, is related to internal hemorrhoid and spinal cord injury, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Hemorrhoid is MMP9 (Matrix Metallopeptidase 9), and among its related pathways/superpathways are Endocytic Trafficking of EGFR and Microglia Activation During Neuroinflammation: Microglia Polarization. The drugs Bupivacaine and Nitrendipine have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and liver, and related phenotypes are neoplasm and reproductive system

Disease Ontology : 12 A pelvic varix disease characterized by swollen, inflamed veins around the anus or lower rectum.

Wikipedia : 76 Hemorrhoids, also called piles, are vascular structures in the anal canal. In their normal state, they... more...

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Related Diseases for Hemorrhoid

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Diseases in the Hemorrhoid family:

Internal Hemorrhoid

Diseases related to Hemorrhoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 internal hemorrhoid 33.6 MMP9 NOS2
2 spinal cord injury 29.7 MMP9 NOS2
3 perianal hematoma 11.7
4 constipation 11.4
5 anus disease 11.4
6 varicose veins 11.4
7 rectal disease 11.4
8 fecal incontinence 11.0
9 pelvic organ prolapse 10.2
10 melanoma 10.2
11 thrombosis 10.1
12 portal hypertension 10.1
13 skin tag 10.1
14 collagenous colitis 10.1 MMP9 NOS2
15 diverticulitis 10.0 DCXR MMP9
16 mycetoma 10.0 MMP9 NOS2
17 coronary heart disease 1 10.0
18 venous insufficiency 10.0
19 heart disease 10.0
20 malignant anus melanoma 10.0
21 colorectal cancer 9.9
22 cervical cancer 9.9
23 lymphoma 9.9
24 sarcoma 9.9
25 anogenital venereal wart 9.9
26 parametritis 9.9
27 dyspepsia 9.9
28 proctitis 9.9
29 cellulitis 9.9
30 acquired immunodeficiency syndrome 9.9
31 intestinal obstruction 9.9
32 radiation proctitis 9.9
33 proteasome-associated autoinflammatory syndrome 1 9.9 MMP9 NOS2
34 coffin-lowry syndrome 9.8 RPS6KA1 RPS6KA3
35 ehlers-danlos syndrome, hypermobility type 9.8
36 hernia, hiatus 9.8
37 renal cell carcinoma, nonpapillary 9.8
38 anus, imperforate 9.8
39 late-onset retinal degeneration 9.8
40 pulmonary disease, chronic obstructive 9.8
41 myelodysplastic syndrome 9.8
42 anal fistula 9.8
43 b-cell lymphomas 9.8
44 crohn's disease 9.8
45 diffuse large b-cell lymphoma 9.8
46 hemangioma 9.8
47 liver cirrhosis 9.8
48 liver disease 9.8
49 mantle cell lymphoma 9.8
50 inflammatory bowel disease 9.8

Graphical network of the top 20 diseases related to Hemorrhoid:



Diseases related to Hemorrhoid
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Symptoms & Phenotypes for Hemorrhoid

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UMLS symptoms related to Hemorrhoid:


nausea and vomiting, constipation, abdominal pain, diarrhea, icterus, rectal tenesmus, dyspepsia, heartburn, pruritus ani, gastrointestinal gas, rectal pain

MGI Mouse Phenotypes related to Hemorrhoid:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.46 MMP9 NOS2 RPS6KA3 SMAD9
2 reproductive system MP:0005389 9.35 KIAA1217 MMP9 NOS2 RPS6KA3 SMAD9
3 skeleton MP:0005390 9.02 KIAA1217 MMP9 NOS2 RPS6KA3 SMAD9
Sources

Drugs & Therapeutics for Hemorrhoid

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Drugs for Hemorrhoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 162)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
2
Nitrendipine Approved, Investigational Phase 4 39562-70-4 4507
3
Captopril Approved Phase 4 62571-86-2 44093
4
Hydrochlorothiazide Approved, Vet_approved Phase 4 58-93-5 3639
5
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 137-58-6 3676
6
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 51-43-4 5816
7
Racepinephrine Approved Phase 4,Phase 3,Not Applicable 329-65-7 838
8
Acetylcholine Approved Phase 4 51-84-3 187
9
Morphine Approved, Investigational Phase 4 57-27-2 5288826
10
Ketamine Approved, Vet_approved Phase 4,Not Applicable,Early Phase 1 6740-88-1 3821
11
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Not Applicable 437-38-7 3345
12
Prilocaine Approved Phase 4,Phase 3 721-50-6 4906
13
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
14
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 175805 71273
15
Glycerol Approved, Investigational Phase 4,Phase 2,Phase 3 56-81-5 753
16
Metronidazole Approved Phase 4,Phase 3 443-48-1 4173
17
Rutin Approved, Experimental, Investigational Phase 4 153-18-4 5280805
18
Menthol Approved Phase 4 2216-51-5 16666
19
Borage oil Approved, Investigational Phase 4
20
Lactulose Approved Phase 4 4618-18-2 11333
21
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
22 Anesthetics, Local Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
23 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
24 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
25 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
26 Vasodilator Agents Phase 4
27
protease inhibitors Phase 4,Not Applicable
28 diuretics Phase 4
29 calcium channel blockers Phase 4,Not Applicable
30 HIV Protease Inhibitors Phase 4,Not Applicable
31 Sodium Chloride Symporter Inhibitors Phase 4
32 Antihypertensive Agents Phase 4
33 Calcium, Dietary Phase 4,Not Applicable
34 Natriuretic Agents Phase 4
35 Angiotensin-Converting Enzyme Inhibitors Phase 4
36 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
37 Cholinergic Agents Phase 4,Not Applicable
38 Pharmaceutical Solutions Phase 4,Not Applicable
39 Analgesics Phase 4,Phase 2,Not Applicable,Early Phase 1
40 Adjuvants, Anesthesia Phase 4,Not Applicable
41 Sodium Channel Blockers Phase 4,Phase 2,Phase 3
42 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Not Applicable
43 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 3
44 Anti-Asthmatic Agents Phase 4,Phase 3,Not Applicable
45 Mydriatics Phase 4,Phase 2,Phase 3,Not Applicable
46 Autonomic Agents Phase 4,Phase 2,Phase 3,Not Applicable
47 Epinephryl borate Phase 4,Phase 3,Not Applicable
48 Respiratory System Agents Phase 4,Phase 2,Phase 3,Not Applicable
49 Bronchodilator Agents Phase 4,Phase 3,Not Applicable
50 Acetylcholine Release Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 131)
# Name Status NCT ID Phase Drugs
1 HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial Unknown status NCT02216305 Phase 4
2 Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy Unknown status NCT01099605 Phase 4
3 Treatment of Hypertension in Tibetan Adult Population Unknown status NCT02217852 Phase 4 Nitrendipine;Hydrochlorothiazide;Captopril,Hydrochlorothiazide;Beijing hypotensive No.0
4 A Comparative Efficacy and Safety Study of Compound Carraghenates Cream With Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids Completed NCT01881282 Phase 4 Carraghenates Cream;Mayinglong Musk Hemorrhoid Ointment
5 Pain Relief for Thrombosed External Haemorrhoids Completed NCT00717782 Phase 4
6 Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids Completed NCT00841620 Phase 4
7 Comparison Between Excisional Hemorrhoidectomy and Haemorrhoidal Dearterialisation With Anopexy Completed NCT01263431 Phase 4
8 Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease Completed NCT02782455 Phase 4 Flavonoids;CDobi
9 Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the Hemorrhoids Completed NCT02046772 Phase 4 Bupivacaine low dose;Bupivacaine standard dose;Morphine Chloride
10 Effect of Perioperative i.v. Low-dose S(+) Ketamine Completed NCT00354029 Phase 4 S (+) Ketamine;Placebo
11 Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl Completed NCT01880775 Phase 4 Prilocaine;Bupivacaine
12 Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery Completed NCT02961855 Phase 4 anesthesics plus antiinflammatory, CLIFE1;local anesthesics, CLIFE2
13 Perianal Nerval Block in Proctological Interventions Recruiting NCT03405922 Phase 4 Placebo 40 mL Saline 0.9%;40 mL Ropivacain 0.5%
14 Irritation and Anal Bleeding in Patients Affected by Hemorrhoids. Active, not recruiting NCT03569930 Phase 4 flavonoid-based supplements;Centella Complex
15 Topical Versus Oral Metronidazole Following Excisional Haemorrhoidectomy Not yet recruiting NCT03343509 Phase 4 Metronidazole Oral;Metronidazole Ointment;Placebo Oral Tablet;Placebo Ointment
16 Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures Terminated NCT00160290 Phase 4 Lactulose;Plantago ovata
17 Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy Terminated NCT02104414 Phase 4 Exparel;Bupivacaine HCl with Epinephrine;Normal Saline
18 Local Versus General Anaesthesia in Stapled Hemorrhoidectomy Withdrawn NCT00512044 Phase 4
19 Multi-Drug Analgesia vs. Standard Solution for Anal Surgery Withdrawn NCT03105674 Phase 4 Multi-drug local anesthetics (Combination);Standard local anesthetics (Combination)
20 Hepatitis C Virus Post-Exposure Prophylaxis for Health Care Workers Withdrawn NCT01766115 Phase 4 Telaprevir
21 Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids Unknown status NCT01961739 Phase 2, Phase 3 2% lidocaine;placebo
22 Prospective Randomized Trial Comparing THD Versus Stapler Operation for 3rd Degree Hemorrhoids Unknown status NCT00823784 Phase 3
23 Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills Unknown status NCT00861562 Phase 3 Imescard water smartweed composed pills;Placebo
24 Efficacy and Tolerability of the Use of Varicell Compared With Daflon Unknown status NCT01321619 Phase 3 Daflon;Varicell placebo
25 Efficacy and Safety Evaluation of the Imescard Compound Water Smartweed Ointment Unknown status NCT00935948 Phase 3 Imescard compound water smartweed ointment;Placebo
26 Diet and Lifestyle Intervention Study in Postpartum Women in China Unknown status NCT01039051 Phase 2, Phase 3
27 Safety and Short Term Effectiveness of EEA Versus PPH Stapler for III Degree Hemorrhoids Completed NCT01413867 Phase 3
28 Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids Completed NCT02130830 Phase 3 Topical 2,5% lidocaine + 2,5% prilocaine gel;Placebo
29 A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3 Completed NCT02010099 Phase 2, Phase 3 PP110 Gel;PP110 Medicated wipes;Preparation-H Cream
30 Study About Patient Comfort and Long-term Outcome After Stapled Hemorrhoidopexy Completed NCT01533363 Phase 3
31 Study of Pain Control in Hemorrhoidectomy Completed NCT00890721 Phase 3 SKY0402;Placebo
32 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Completed NCT00744848 Phase 3 Bupivacaine HCl;SKY0402
33 Effectiveness of Metronidazole in Pain Control Posthemorrhoidectomy Completed NCT02328144 Phase 3 Metronidazole;Placebo
34 Randomized Controlled Trial Comparing Transanal Doppler-guided Arterial Ligation With Mucopexy and Stapled Haemorrhoidopexy Completed NCT01240772 Phase 3
35 Efficacy and Safety Study to Treat Subjects With Symptomatic Internal Hemorrhoids Terminated NCT01355874 Phase 3 Iferanserin;Placebo;Iferanserin + Placebo
36 Evaluation of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms Unknown status NCT02301052 Phase 1, Phase 2 Leek topical cream;placebo topical cream;Anti-hemorrhoid topical cream
37 Posthemorrhoidectomy Pain Management With Electronic Bidet or Sitz Bath Unknown status NCT02353156 Phase 2
38 Efficacy Study of Iferanserin to Treat Hemorrhoids Completed NCT01483833 Phase 2 Iferanserin;Placebo
39 To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids Completed NCT01041911 Phase 2 Euphorbia tablets;Euphorbia tablets;Euphorbia tablets;Placebo tablets
40 Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids Completed NCT02689856 Phase 2 Hydrocortisone acetate and lidocaine hydrochloride;Placebo control;Hydrocortisone acetate;Lidocaine hydrochloride
41 Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids Completed NCT01913158 Phase 2 Anucort-HC, 25 Mg Rectal Suppository;Placebo suppository
42 Study of a New Circular Anal Dilator Completed NCT00693459 Phase 1, Phase 2
43 Ticagrelor and Eptifibatide Bolus-Only Versus Ticagrelor and Eptifibatide Bolus Plus Abbreviated Infusion Completed NCT01919723 Phase 2 Ticagrelor;Eptifibatide
44 Occupational Therapy Modulates the Pain in Cancer Patient Under Palliative Care Completed NCT02102178 Phase 2
45 Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits Completed NCT00487942 Phase 2 armodafinil;armodafinil;armodafinil;placebo
46 Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease Recruiting NCT03791775 Phase 2 Polidocanol foam (Atossisclerol® 3%)
47 Study of the Safety and Efficacy of Hydrocortisone Acetate Suppositories, 25 mg in the Treatment of Symptomatic Internal Hemorrhoids Not yet recruiting NCT03335774 Phase 2 Hydrocortisone Acetate Suppository, 25 mg;Placebo (Vehicle) Suppository
48 Consolidation Therapy With Hu3S193 for Women With Ovarian, Primary Peritoneal or Fallopian Tube Cancer Terminated NCT01137071 Phase 2
49 Prevention and/or Reduction of Hemorrhoids and/or Thrombosed External Hemorrhoids Using the HEM-AVERT Perianal Stabilizer Instrument Completed NCT00487045 Phase 1
50 Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain Recruiting NCT03797703 Phase 1 Lidocaine Hydrochloride 2% gel enema

Search NIH Clinical Center for Hemorrhoid

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: hemorrhoids

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Genetic Tests for Hemorrhoid

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Anatomical Context for Hemorrhoid

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MalaCards organs/tissues related to Hemorrhoid:

41
Skin, Kidney, Liver, Bone, Heart, Colon, Spinal Cord
Sources

Publications for Hemorrhoid

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Articles related to Hemorrhoid:

(show top 50) (show all 864)
# Title Authors Year
1
Traditional and modern aspects of hemorrhoid treatment in Iran: a review. ( 29526242 )
2018
2
Hemorrhoid, External ( 29763185 )
2018
3
The Clinical Efficacy of Infrared Photocoagulation Versus Closed Hemorrhoidectomy in Treatment of Hemorrhoid. ( 29399307 )
2018
4
Novel Nonsurgical Treatment of Intractable Bleeding in Hemorrhoid Patients on Anticoagulants. ( 29774789 )
2018
5
The Effect of Nonoperative Management of Chronic Anal Fissure and Hemorrhoid Disease on Bowel Function Patient-Reported Outcomes. ( 30192331 )
2018
6
An interesting case of anal melanoma caused liver metastases due to misdiagnosed as hemorrhoids. ( 30260788 )
2018
7
Management of retrorectal hematoma after stapled transanal rectal resection for prolapsed hemorrhoids associated with occult rectal prolapse and obstructed defecation syndrome. ( 30523515 )
2018
8
Hemorrhoids during pregnancy: Sitz bath vs. ano-rectal cream: A comparative prospective study of two conservative treatment protocols. ( 29055673 )
2018
9
Hemorrhoids: what are the options in 2018? ( 29076869 )
2018
10
Oxidized cellulose as hemostatic agent to prevent bleeding after high-risk endoscopic resection of rectal laterally spreading tumor overlying hemorrhoids. ( 29396970 )
2018
11
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Hemorrhoids. ( 29420423 )
2018
12
Hemorrhoids: Diagnosis and Treatment Options. ( 29431977 )
2018
13
Office management of hemorrhoids. ( 29487411 )
2018
14
Anorectal Complaints: Hemorrhoids, Fissures, Abscesses, Fistulae. ( 29487494 )
2018
15
Rethinking What We Know About Hemorrhoids. ( 29601902 )
2018
16
Mucopexy-recto anal lifting: a standardized minimally invasive method of managing symptomatic hemorrhoids, with an innovative suturing technique and the HemorPex System®. ( 29652112 )
2018
17
Procedure for Prolapse and Hemorrhoids Complication Solutions: Repair of a Completely Closed Off Rectum. ( 29722732 )
2018
18
Conservative Treatment of Hemorrhoids Deserves More Attention in Guidelines and Clinical Practice. ( 29771798 )
2018
19
Long-term follow-up of Starionâ„¢ versus Harmonic Scalpelâ„¢ hemorrhoidectomy for grade III and IV hemorrhoids. ( 29804709 )
2018
20
Clopidogrel bisulfate (Plavix) does not increase bleeding complications in patients undergoing rubber band ligation for symptomatic hemorrhoids. ( 29936995 )
2018
21
Correction to: Distal Doppler-guided transanal hemorrhoidal dearterialization with mucopexy versus conventional hemorrhoidectomy for grade III and IV hemorrhoids: postoperative morbidity and long-term outcomes. ( 29948521 )
2018
22
Transanal hemorrhoidal dearterialization versus stapled hemorrhoidectomy in the treatment of hemorrhoids: A PRISMA-compliant updated meta-analysis of randomized control trials. ( 30024532 )
2018
23
Modified Doppler-guided laser procedure for the treatment of second- and third-degree hemorrhoids. ( 30087534 )
2018
24
Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study. ( 30276625 )
2018
25
Correction to: Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study. ( 30387021 )
2018
26
Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases. ( 30411508 )
2018
27
Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials. ( 30421308 )
2018
28
Partial Stapled Hemorrhoidopexy Versus Circumferential Stapled Hemorrhoidopexy for Grade III to IV Prolapsing Hemorrhoids: A Randomized, Noninferiority Trial. ( 30489326 )
2018
29
Stapled Hemorrhoidectomy Versus Transanal Hemorrhoidal Dearterialization in the Treatment of Hemorrhoids: An Updated Meta-Analysis. ( 30540639 )
2018
30
Hemorrhoid is associated with increased risk of peripheral artery occlusive disease: A nationwide cohort study. ( 28268046 )
2017
31
Association between hemorrhoid and risk of coronary heart disease: A nationwide population-based cohort study. ( 28767586 )
2017
32
Anal Melanoma in an Elderly Woman Masquerading as Hemorrhoid. ( 29387509 )
2017
33
Twenty Years of a Veterans' Spinal Cord Injury Colorectal Clinic: Flexible Sigmoidoscopy and Multiple Hemorrhoid Ligation. ( 28267007 )
2017
34
Selective embolization of the superior rectal artery: An alternative to hemorrhoid surgery? ( 29042023 )
2017
35
The Use of Fluorescence Angiography for Confirmation of Hemorrhoid Dearterialization. ( 28822382 )
2017
36
Hemorrhoid Treatment Needs a Relook: More Room for Conservative Management Even in Advanced Grades of Hemorrhoids. ( 29217916 )
2017
37
The Use of Fluorescence Angiography for Confirmation of Hemorrhoid Dearterialization. ( 30454267 )
2017
38
Linking Brain Arteriovenous Malformations With Anorectal Hemorrhoids: A Clinical and Anatomical Review. ( 28696502 )
2017
39
May radiofrequency be the best choice for III-IV degree hemorrhoids? ( 27845508 )
2017
40
Are Hemorrhoids Associated with False-Positive Fecal Immunochemical Test Results? ( 27873508 )
2017
41
Hemorrhoids and the recurrent attempts to destroy them. ( 27999954 )
2017
42
LBet 88: a new device for outpatient treatment of selected grade III hemorrhoids. ( 28025708 )
2017
43
Adequate dietary fiber supplement and TONE can help avoid surgery in most patients with advanced hemorrhoids. ( 28150480 )
2017
44
Association of chronic obstructive pulmonary disease and hemorrhoids: A nationwide cohort study. ( 28272246 )
2017
45
Early Experience With a Partial Stapled Hemorrhoidopexy for Treating Patients With Grades III-IV Prolapsing Hemorrhoids. ( 28289661 )
2017
46
Bidet toilet use and incidence of hemorrhoids or urogenital infections: A one-year follow-up web survey. ( 28316906 )
2017
47
Treatment of Prolapsing Hemorrhoids in HIV-Infected Patients with Tissue-Selecting Technique. ( 28356909 )
2017
48
Distal Doppler-guided transanal hemorrhoidal dearterialization with mucopexy versus conventional hemorrhoidectomy for grade III and IV hemorrhoids: postoperative morbidity and long-term outcomes. ( 28451767 )
2017
49
The Evaluation and Office Management of Hemorrhoids for the Gastroenterologist. ( 28567655 )
2017
50
Sonographic appearance of anal cushions of hemorrhoids. ( 28611519 )
2017
Sources

Variations for Hemorrhoid

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Expression for Hemorrhoid

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Search GEO for disease gene expression data for Hemorrhoid.
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Pathways for Hemorrhoid

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Pathways related to Hemorrhoid according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Endocytic Trafficking of EGFR 64
Show member pathways
 11.26 RPS6KA1 RPS6KA3
2
Microglia Activation During Neuroinflammation: Microglia Polarization 65
11.17 MMP9 NOS2
3
AGE/RAGE pathway 1
11.08 MMP9 NOS2
4
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 10.96 MMP9 NOS2
5
FGF signaling pathway 1
10.63 MMP9 RPS6KA1
6
Melanocyte Development and Pigmentation 64
10.24 RPS6KA1 RPS6KA3
Sources

GO Terms for Hemorrhoid

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Biological processes related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell growth GO:0030307 9.32 RPS6KA1 RPS6KA3
2 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 9.26 RPS6KA1 RPS6KA3
3 positive regulation of cell differentiation GO:0045597 9.16 RPS6KA1 RPS6KA3
4 regulation of DNA-templated transcription in response to stress GO:0043620 8.96 RPS6KA1 RPS6KA3
5 regulation of translation in response to stress GO:0043555 8.62 RPS6KA1 RPS6KA3

Molecular functions related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 8.96 RPS6KA1 RPS6KA3
2 ribosomal protein S6 kinase activity GO:0004711 8.62 RPS6KA1 RPS6KA3
Sources

Sources for Hemorrhoid

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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