MCID: HMR005
MIFTS: 46

Hemorrhoid

Categories: Cardiovascular diseases, Gastrointestinal diseases, Skin diseases

Aliases & Classifications for Hemorrhoid

MalaCards integrated aliases for Hemorrhoid:

Name: Hemorrhoid 12 74 15 17
Hemorrhoids 42 43 15 71
Hemorrhoidal Disease 12
Rectal Diseases 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9746
ICD9CM 34 455
MeSH 43 D006484
NCIt 49 C26792
SNOMED-CT 67 70153002
UMLS 71 C0019112 C0034882

Summaries for Hemorrhoid

MedlinePlus : 42 Hemorrhoids are swollen, inflamed veins around the anus or lower rectum. They are either inside the anus or under the skin around the anus. They often result from straining to have a bowel movement. Other factors include pregnancy, aging and chronic constipation or diarrhea. Hemorrhoids are very common in both men and women. About half of all people have hemorrhoids by age 50. The most common symptom of hemorrhoids inside the anus is bright red blood covering the stool, on toilet paper or in the toilet bowl. Symptoms usually go away within a few days. If you have rectal bleeding you should see a doctor. You need to make sure bleeding is not from a more serious condition such as colorectal or anal cancer. Treatment may include warm baths and a cream or other medicine. If you have large hemorrhoids, you may need surgery and other treatments. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Hemorrhoid, also known as hemorrhoids, is related to internal hemorrhoid and constipation, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Hemorrhoid is MMP9 (Matrix Metallopeptidase 9). The drugs Aspirin and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include skin, colon and testes.

Disease Ontology : 12 A pelvic varix disease characterized by swollen, inflamed veins around the anus or lower rectum.

Wikipedia : 74 Hemorrhoids, also called piles, are vascular structures in the anal canal. In their normal state, they... more...

Related Diseases for Hemorrhoid

Diseases in the Hemorrhoid family:

Internal Hemorrhoid

Diseases related to Hemorrhoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 387)
# Related Disease Score Top Affiliating Genes
1 internal hemorrhoid 33.1 VAT1 NOS2 MMP9 FLNA ATP4A ATP12A
2 constipation 32.2 NOS2 FLNA ATP4A ATP12A APOLD1
3 malignant anus melanoma 30.8 MLANA APOLD1
4 rectal disease 30.8 KLK3 DCXR CRP CEACAM5 APOLD1 ALB
5 venous insufficiency 30.6 MMP9 F2 CRP
6 thrombophlebitis 30.5 F2 CRP ALB
7 fournier gangrene 30.4 F2 ALB
8 intussusception 30.4 CRP APOLD1 ALB
9 chronic venous insufficiency 30.4 MMP9 F2 CRP
10 proctitis 30.4 KLK3 CRP APOLD1
11 esophageal varix 30.3 F2 ATP4A ATP12A ALB
12 dieulafoy lesion 30.2 ATP4A ATP12A APOLD1
13 anal fistula 30.1 MMP9 MIR6086 MIR3609 MIR1185-1 APOLD1
14 gastroenteritis 30.1 MMP9 CRP ALB
15 anus cancer 30.1 DCXR CEACAM5 APOLD1
16 giardiasis 30.1 ATP4A ATP12A ALB
17 functional diarrhea 30.1 ATP4A ATP12A
18 hernia, hiatus 30.0 CRP ATP4A ATP12A
19 rectum adenocarcinoma 29.8 DCXR CEACAM5 APOLD1
20 compartment syndrome 29.8 F2 CRP ALB
21 vascular disease 29.8 NOS2 MMP9 F2 CRP ALB
22 lactose intolerance 29.7 CRP ATP4A ATP12A ALB
23 heart valve disease 29.7 F2 CRP ALB
24 pulmonary disease, chronic obstructive 29.7 MMP9 CRP ATP12A ALB
25 endocarditis 29.6 F2 CRP ALB
26 exanthem 29.4 F2 CRP ATP4A ATP12A ALB
27 migraine with or without aura 1 29.1 F2 CRP ATP4A ATP12A ALB
28 acute cystitis 29.1 KLK3 F2 CRP ALB
29 intestinal volvulus 28.9 F2 CRP ATP4A ATP12A APOLD1 ALB
30 cholangitis 28.9 F2 CRP CEACAM5 ALB
31 intestinal obstruction 28.3 FLNA CRP CEACAM5 ATP4A ATP12A APOLD1
32 perianal hematoma 12.0
33 varicose veins 11.7
34 anus disease 11.2
35 thrombosis 10.7
36 hepatic flexure cancer 10.5 DCXR APOLD1
37 splenic flexure cancer 10.5 DCXR APOLD1
38 portal hypertension 10.5
39 pelvic organ prolapse 10.5
40 lentigo maligna melanoma 10.5 MMP9 MLANA
41 immuno-osseous dysplasia 10.5 NOS2 ALB
42 pancreatic vasoactive intestinal peptide producing tumor 10.5 ATP4A ATP12A
43 lateral ventricle meningioma 10.5 CRP APOLD1
44 hemangioma of intra-abdominal structure 10.5 ATP4A ATP12A
45 displacement of cardia through esophageal hiatus 10.5 ATP4A ATP12A
46 acquired gastric outlet stenosis 10.5 ATP4A ATP12A
47 angiodysplasia of intestine 10.4 ATP4A ATP12A
48 benzylpenicillin allergy 10.4 ATP4A ATP12A
49 median arcuate ligament syndrome 10.4 ATP4A ATP12A
50 granulomatous gastritis 10.4 ATP4A ATP12A

Graphical network of the top 20 diseases related to Hemorrhoid:



Diseases related to Hemorrhoid

Symptoms & Phenotypes for Hemorrhoid

UMLS symptoms related to Hemorrhoid:


nausea and vomiting, constipation, abdominal pain, diarrhea, icterus, rectal tenesmus, dyspepsia, heartburn, pruritus ani, gastrointestinal gas, rectal pain

Drugs & Therapeutics for Hemorrhoid

Drugs for Hemorrhoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 199)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
3
Prilocaine Approved Phase 4 721-50-6 4906
4
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
5
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
6
Morphine Approved, Investigational Phase 4 57-27-2 5288826
7
Metronidazole Approved Phase 4 443-48-1 4173
8
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
9
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
10
tannic acid Approved Phase 4 1401-55-4
11
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
12
Ethanol Approved Phase 4 64-17-5 702
13
Estazolam Approved, Illicit Phase 4 29975-16-4 3261
14
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
15
Magnesium oxide Approved Phase 4 1309-48-4 14792
16
Ibuprofen Approved Phase 4 15687-27-1 3672
17
Acetaminophen Approved Phase 4 103-90-2 1983
18
Mineral oil Approved, Vet_approved Phase 4 8042-47-5
19
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
20
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
21
Glycerol Approved, Investigational Phase 4 56-81-5 753
22
Rutin Approved, Experimental, Investigational Phase 4 153-18-4 5280805
23
Menthol Approved Phase 4 2216-51-5 16666
24
Borage oil Approved, Investigational Phase 4
25
Lactulose Approved Phase 4 4618-18-2 11333
26
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
27
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
28 Fibrinolytic Agents Phase 4
29 Platelet Aggregation Inhibitors Phase 4
30 Coagulants Phase 4
31 Calcium, Dietary Phase 4
32 Calcium Dobesilate Phase 4
33 abobotulinumtoxinA Phase 4
34 Acetylcholine Release Inhibitors Phase 4
35 Cholinergic Agents Phase 4
36 Botulinum Toxins, Type A Phase 4
37 Botulinum Toxins Phase 4
38 Adjuvants, Anesthesia Phase 4
39 Anti-Inflammatory Agents, Non-Steroidal Phase 4
40 Cyclooxygenase Inhibitors Phase 4
41 Cathartics Phase 4
42 Laxatives Phase 4
43 Anti-Bacterial Agents Phase 4
44 Anti-Infective Agents Phase 4
45 Antiprotozoal Agents Phase 4
46 Antiparasitic Agents Phase 4
47 Anticonvulsants Phase 4
48 Analgesics, Opioid Phase 4
49 Analgesics, Non-Narcotic Phase 4
50 BB 1101 Phase 4

Interventional clinical trials:

(show top 50) (show all 181)
# Name Status NCT ID Phase Drugs
1 Prospective and Randomized Trial Comparing Dopplper-Guided Transanal Hemorrhoid Artery Ligation With Recto-anal Repair (HAL-RAR) Versus Excisional Hemorrhoidectomy for the Treatment of Grade III-IV Hemorrhoids Unknown status NCT02216305 Phase 4
2 Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy: A Randomized Double-blind Controlled Trial Unknown status NCT01099605 Phase 4
3 The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Continuing or Discontinuing on Aspirin: a Multicenter, Double-blind, Placebo-controlled, Randomized Clinical Trial Unknown status NCT01549418 Phase 4 Aspirin (ASA);Placebo
4 Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease a Randomised Triple Blind Controlled Trial Completed NCT02782455 Phase 4 Flavonoids;CDobi
5 A Comparative Clinical Research on Therapeutic Effect and Safety of Compound Carraghenates Cream Versus Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids Completed NCT01881282 Phase 4 Carraghenates Cream;Mayinglong Musk Hemorrhoid Ointment
6 Prospective Randomized Trial on Surgical Treatment of Grade 3 Hemorrhoids: Hemorrhoidectomy Versus Doppler-guided Transanal Haemorrhoidal Dearterialisation and Anopexy Completed NCT01263431 Phase 4
7 Randomized Clinical Trial of Botulinum Toxin Injection for Pain Relief in Patients With Thrombosed External Haemorrhoids Completed NCT00717782 Phase 4
8 The Comparison of the Discharge Conditions and Efficacy of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl in Outpatient Minor Perianal Surgery Completed NCT01880775 Phase 4 Prilocaine;Bupivacaine
9 Symptom Control 1-year After Circular Stapler Anopey or Diathermy Excision for Prolapsed Haemorrhoids: an International Randomsed Trial (the STOPP-trial Completed NCT00841620 Phase 4
10 Effect of Perioperative i.v. Low-dose S(+) Ketamine in Patients Undergoing Hemorrhoidectomy Completed NCT00354029 Phase 4 S (+) Ketamine;Placebo
11 Perianal Nerval Block in Proctological Interventions: a Prospective Randomized Double Blinded Study Completed NCT03405922 Phase 4 Placebo 40 mL Saline 0.9%;40 mL Ropivacain 0.5%
12 Double-blinded Multicenter Randomized Clinical Trial to Evaluate the Efficacy and Safety of CLIFE1 and CLIFE2 Gels in Benign Anorectal Surgery Completed NCT02961855 Phase 4 anesthesics plus antiinflammatory, CLIFE1;local anesthesics, CLIFE2
13 Assessment of the Analgesic Efficacy of Morphine Chloride in Addition to a Low Dose Solution of Spinal Anaesthetic in Hemorrhoidectomy Compared to a Standard Dose of Spinal Local Anaesthetic. Simple Blind, Randomized, With Blinded Evaluation by Third Parties Clinical Trial. Completed NCT02046772 Phase 4 Bupivacaine low dose;Bupivacaine standard dose;Morphine Chloride
14 A Prospective, Multicentre, Double-Blinded Randomised Controlled Trial Comparing Topical Versus Oral Metronidazole in Reducing Post-Operative Pain Following Excisional Haemorrhoidectomy Recruiting NCT03343509 Phase 4 Metronidazole Oral;Metronidazole Ointment;Placebo Oral Tablet;Placebo Ointment
15 The First Affiliated Hospital of Guangzhou University of Chinese Medicine Recruiting NCT03997058 Phase 4 Oral estazolam medication
16 Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery Recruiting NCT03738904 Phase 4
17 Irritation and Anal Bleeding in Patients Affected by Hemorrhoids: Comparative Evaluation of Three Different Treatments. Active, not recruiting NCT03569930 Phase 4 flavonoid-based supplements;Centella Complex
18 Comparison of Rectal Infiltration of Exparel vs. 0.25% Bupivacaine With Epinephrine vs. Placebo for Analgesic Benefit Following Hemorrhoidectomy Terminated NCT02104414 Phase 4 Exparel;Bupivacaine HCl with Epinephrine;Normal Saline
19 An Open, Randomized, Parallel Group, Single Center Study to Investigate the Effect of Lactulose Versus Plantago Ovate on the Quality of Life of Patients With Hard Stools and Hemorrhoids or Anal Fissure Terminated NCT00160290 Phase 4 Lactulose;Plantago ovata
20 Local vs General Anaesthesia in Stapled Hemorrhoidectomy: A Multicentric Controlled Randomized Trial Withdrawn NCT00512044 Phase 4
21 Multi-drug Analgesia Versus Standard Solution for Perianal Block - A Prospective Study to Determine the Efficacy, Cost and Narcotic Consumption in the Post-operative Period Withdrawn NCT03105674 Phase 4 Multi-drug local anesthetics (Combination);Standard local anesthetics (Combination)
22 Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills Unknown status NCT00861562 Phase 3 Imescard water smartweed composed pills;Placebo
23 Phase 3 Clinical Trial - Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed, Adrenalin and Hamamelis Ointment Unknown status NCT00935948 Phase 3 Imescard compound water smartweed ointment;Placebo
24 Prospective Randomized Trial Comparing Transanal Doppler de-Arterialization (THD) Versus Stapler Operation for 3rd Degree Hemorrhoids Unknown status NCT00823784 Phase 3
25 Double Blinded Randomized Clinical Trial of the Efficacy of Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids Unknown status NCT01961739 Phase 2, Phase 3 2% lidocaine;placebo
26 Study Clinical, Multicenter,Phase III,Prospective,Randomized,Comparative Double Blind/Double-dummy to Assess the Efficacy and Tolerability of the Use of Varicell in Reducing the Symptoms Caused by Chronic Venous Insufficiency and Hemorrhoidal Syndrome When Compared With Daflon Unknown status NCT01321619 Phase 3 Daflon;Varicell placebo
27 Randomized Controlled Trials of Diet and Lifestyle Intervention to Promote Chinese Postpartum Women's Health Unknown status NCT01039051 Phase 2, Phase 3
28 Patient Comfort After Stapled Hemorrhoidopexy Long Term Results of a Randomized Controlled Trial Completed NCT01533363 Phase 3
29 Topical Anesthesia Versus Placebo to Decrease Post Procedure Pain in Rubber Band Ligation for the Treatment of Grade I - III Symptomatic Internal Hemorrhoids. A Single Institution, Double Blinded, Placebo Controlled Trial. Completed NCT02130830 Phase 3 Topical 2,5% lidocaine + 2,5% prilocaine gel;Placebo
30 A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Safety and Efficacy of a Single Administration of SKY0402 for Prolonged Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Completed NCT00890721 Phase 3 SKY0402;Placebo
31 A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3 Completed NCT02010099 Phase 2, Phase 3 PP110 Gel;PP110 Medicated wipes;Preparation-H Cream
32 Effectiveness of Metronidazole Versus Homologated Placebo in Pain Control Posthemorrhoidectomy Completed NCT02328144 Phase 3 Metronidazole;Placebo
33 Safety and Short Term Effectiveness of EEA Stapler vs PPH Stapler in the Treatment of III Degree Haemorrhoids. Prospective Randomized Controlled Trial Completed NCT01413867 Phase 3
34 Phase 3, Multicenter, Randomized, Double-Blind, Parallel-group, Active-control Study to Evaluate the Safety and Efficacy of a Single Administration of SKY0402 for Prolonged Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Completed NCT00744848 Phase 3 Bupivacaine HCl;SKY0402
35 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Budesonide Foam (2 mg/25 mL BID for 2 Weeks, Followed by 2 mg/25 mL QD for 4 Weeks) Versus Placebo in Subjects With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis Completed NCT01008423 Phase 3 Budesonide;Placebo
36 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Budesonide Foam (2 mg/25 mL BID for 2 Weeks, Followed by 2 mg/25 mL QD for 4 Weeks) Versus Placebo in Subjects With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis Completed NCT01008410 Phase 3 Budesonide;Placebo
37 Randomized Trial Comparing Drainage Versus no Drainage Following Rectal Excision With Low Anastomosis for Rectal Cancer Completed NCT01269567 Phase 3
38 Aquanet Bowel Cleansing Device Versus Oral Sodium Picosulfate for Pre-endoscopy Bowel Preparation: Propensity Score Analysis for Interventional Effectiveness Evaluation Completed NCT03074448 Phase 3 Sodium Picosulfate
39 Sclerotherapy With Polidocanol Foam In The Management Of First, Second And Third-Grade Hemorrhoidal Disease In Patients With Bleeding Disorders: A Prospective Cohort Study Recruiting NCT04188171 Phase 2, Phase 3
40 A Phase 3 Study of BBI-608 in Combination With 5-Fluorouracil, Leucovorin, Irinotecan (FOLFIRI) in Adult Patients With Previously Treated Metastatic Colorectal Cancer (CRC). Active, not recruiting NCT02753127 Phase 3 Napabucasin;Fluorouracil;Leucovorin;Irinotecan;Bevacizumab
41 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of Intra-Anal Application of Iferanserin (10 mg) as a 0.5% Ointment in Subjects With Symptomatic Internal Hemorrhoids Terminated NCT01355874 Phase 3 Iferanserin;Placebo;Iferanserin + Placebo
42 A Phase 3, Open Label, Multicenter Study to Assess the Safety and Tolerability of Budesonide Foam in Subjects With Active Ulcerative Proctitis or Proctosigmoiditis Terminated NCT01349673 Phase 3 Budesonide Foam
43 Double Blind Randomized Placebo-control Trial of Allium Ampeloprasum Spp.Iranicum Cream Effect for the Management of Hemorrhoids Symptoms Unknown status NCT02301052 Phase 1, Phase 2 Leek topical cream;placebo topical cream;Anti-hemorrhoid topical cream
44 Single Blind, Randomized Controlled, Multicenter Study to Evaluate the Efficacy and Convenience of Electronic Bidet With Very Low Force Flow Fountain System for Pain Control and Wound Healing After Operation for Anal Disease, Compared to Conventional Sitz Bath Unknown status NCT02353156 Phase 2
45 Double-blind, Randomized, Placebo-controlled, Dose Response Study to Evaluate the Safety and Efficacy of Three Doses of Euphorbia Prostrata Dry Extract Tablets in Patients of Hemorrhoids Completed NCT01041911 Phase 2 Euphorbia tablets;Euphorbia tablets;Euphorbia tablets;Placebo tablets
46 A Randomized, Dose-Ranging, Double Blind Study of Lidocaine Hydrochloride and/or Hydrocortisone Acetate (Alone or in Combination) in the 14-Day Twice-Daily Treatment of Grade I or II Hemorrhoids Completed NCT02689856 Phase 2 Hydrocortisone acetate and lidocaine hydrochloride;Placebo control;Hydrocortisone acetate;Lidocaine hydrochloride
47 Feasibility Study of a New Circular Anal Dilator for Transanal Hemorrhoidectomy Completed NCT00693459 Phase 1, Phase 2
48 Protocol for the Study of the Effects of S-MPEC (Iferanserin) in Patients With Hemorrhoids Completed NCT01483833 Phase 2 Iferanserin;Placebo
49 A Randomized, Double-Blind, Vehicle-Controlled, Multicenter Study to Evaluate Safety and Efficacy of Anucort HC TM (Hydrocortisone Acetate) 25mg Rectal Suppositories in the Treatment of Symptomatic Internal Hemorrhoids Completed NCT01913158 Phase 2 Anucort-HC, 25 Mg Rectal Suppository;Placebo suppository
50 A Phase 2 Study of GVAX Colon Vaccine (With Cyclophosphamide) and Pembrolizumab in Patients With Mismatch Repair-Proficient (MMR-p) Advanced Colorectal Cancer Completed NCT02981524 Phase 2 CY;Pembrolizumab

Search NIH Clinical Center for Hemorrhoid

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Benzocaine
BENZOCAINE PWDR
Hydrocortisone
hydrocortisone acetate
HYDROCORTISONE ACETATE PWDR
HYDROCORTISONE ACETONIDE
Hydrocortisone butyrate
hydrocortisone cypionate
hydrocortisone probutate
HYDROCORTISONE PWDR
Hydrocortisone sodium phosphate
Hydrocortisone sodium succinate
hydrocortisone valerate
HYDROCORTISONE,NONSTERILE PWDR
Phenylephrine
Phenylephrine bitartrate
Phenylephrine Hydrochloride
Phenylephrine Tannate
pramoxine
Pramoxine hydrochloride
Psyllium
PSYLLIUM HYDROCOLLOID
Witch Hazel

Cochrane evidence based reviews: hemorrhoids

Genetic Tests for Hemorrhoid

Anatomical Context for Hemorrhoid

MalaCards organs/tissues related to Hemorrhoid:

40
Skin, Colon, Testes, Prostate, Liver, Kidney, Spinal Cord

Publications for Hemorrhoid

Articles related to Hemorrhoid:

(show top 50) (show all 3091)
# Title Authors PMID Year
1
Hemorrhoid Banding: A Cost-Effectiveness Analysis. 61 42
31318773 2019
2
Short Term and Long Term Outcome Following Stapled Haemorrhoidopexy. 42
31599253 2019
3
Acute bilateral drop foot as a complication of prolonged squatting due to haemorrhoid. 42
31625702 2019
4
Bioassay-guided fractionation and identification of wound healing active compound from Pistacia vera L. hull extract. 61
31654800 2020
5
Anal fissure management by the gastroenterologist. 61
31688336 2020
6
Hemorrhoidectomy and Excision of Skin Tags in IBD: Harbinger of Doom or Simply a Disease Running Its Course? 61
31580261 2019
7
Estimating disease burden using Internet data. 61
30488754 2019
8
[HAL-RAR for the treatment of hemorrhoids - a new, non invasive method]. 61
31813242 2019
9
Symptoms of pelvic organ prolapse in women who lift heavy weights for exercise: a cross-sectional survey. 61
31813038 2019
10
Fungating Anal Mass: Extrapulmonary Small Cell Carcinoma Masquerading as a Hemorrhoid. 61
31848872 2019
11
Postoperative discomfort and pain in the management of hemorrhoidal disease: laser hemorrhoidoplasty, a minimal invasive treatment of symptomatic hemorrhoids. 61
31760588 2019
12
Anti-bacterial effects of components from Sanguisorba officinalis L. on Vibrio vulnificus and their soluble epoxide hydrolase inhibitory activity. 61
29790361 2019
13
Triplaris gardneriana seeds extract exhibits in vitro anti-inflammatory properties in human neutrophils after oxidative treatment. 61
31836515 2019
14
Prevalence of and Risk Factors for Diseases in Korean Americans and Native Koreans Undergoing Health Checkup. 61
31639887 2019
15
Symptoms of Discomfort and Problems Associated with Mode of Delivery During the Puerperium: An Observational Study. 61
31752197 2019
16
An unexpected diagnosis of a pigmented mass resembling a thrombosed hemorrhoid: anorectal melanoma. 61
31786326 2019
17
Video anoscopy: results of routine anal examination during colonoscopies. 61
31723578 2019
18
Less is more: creation and validation of a novel, affordable suturing simulator for anorectal surgery. 61
31713097 2019
19
Treatment of hemorrhoids: A survey of surgical practice in Australia and New Zealand. 61
31799299 2019
20
Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids. 61
31337196 2019
21
Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid: An Effective and Less Invasive Strategy for Internal Hemorrhoids. 61
31722520 2019
22
Benign Anal Disease: Implementation of an Educational Program Across Specialties. 61
31252348 2019
23
Excisional Hemorrhoidectomy: Safe in Patients With Crohn's Disease? 61
31633186 2019
24
Diterpenoids with inhibitory activity of nitrite production from Croton floribundus. 61
31639485 2019
25
Complete endoscopic removal of a hemorrhoid medication tube as an anorectal foreign body. 61
31670415 2019
26
Robot-assisted low anterior resection after aluminum potassium sulfate and tannic acid sclerosing therapy for internal hemorrhoids. 61
31664540 2019
27
Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases. 61
30411508 2019
28
Association of Hemorrhoid Vascular Injuries with Cigarette Smoking-An Evaluation with Interesting Prospects. 61
31720374 2019
29
Risk of Anal Cancer Following Benign Anal Disease and Anal Cancer Precursor Lesions: A Danish Nationwide Cohort Study. 61
31597665 2019
30
Dose-volume analysis of predictors for acute anal toxicity after radiotherapy in prostate cancer patients. 61
31601249 2019
31
Awareness of Pregnancy-Associated Health Risks Among Pregnant Women and Male Partners Surveyed in a Prenatal Clinic. 61
31647358 2019
32
Results of purified micronized flavonoid fraction in the treatment of categorized type III chronic pelvic pain syndrome: a randomized controlled trial. 61
31615318 2019
33
Stapled Hemorrhoidectomy Versus Transanal Hemorrhoidal Dearterialization in the Treatment of Hemorrhoids: An Updated Meta-analysis: Erratum. 61
31593051 2019
34
Comparative Study of 0.2% Glyceryl Trinitrate Ointment for Pain Reduction after Hemorrhoidectomy Surgery. 61
31803842 2019
35
Pope Leo XII's death: the twist to a longstanding dispute by novel historical documents and paleopathographic analysis. 61
31593209 2019
36
[Clinical analysis of 36 cases of idiopathic intracranial hypertension complicated with iron deficiency anemia]. 61
31510718 2019
37
Hemorrhoidal disease and chronic venous insufficiency: Concomitance or coincidence; results of the CHORUS study (Chronic venous and HemORrhoidal diseases evalUation and Scientific research). 61
31512275 2019
38
Decreased expression of MUC2 due to a decrease in the expression of lectins and apoptotic defects in colitis patients. 61
31198858 2019
39
Potential for Reducing Time to Referral for Colorectal Cancer Patients in Primary Care. 61
31501203 2019
40
Acute Granulomatous Appendicitis and Lower Gastrointestinal Bleeding as the Presenting Features of Crohn's Disease. 61
31728240 2019
41
Promising activity of Anthemis austriaca Jacq. on the endometriosis rat model and isolation of its active constituents. 61
31516332 2019
42
Perianal Crohn's Disease. 61
31507348 2019
43
Hemorrhoids: A range of treatments. 61
31498764 2019
44
Comparison of the effect of Myrtus communis herbal and anti-hemorrhoid ointments on the hemorrhoid symptoms and quality of life in postpartum women with grade I and II internal hemorrhoid: A triple-blinded randomized controlled clinical trial. 61
31433782 2019
45
Hemorrhoid Energy Therapy for Treatment of Deep Chronic Anal Fissures. 61
31737710 2019
46
Biotechnological production of ruscogenins in plant cell and organ cultures of Ruscus aculeatus. 61
31163340 2019
47
Short-term Outcomes of Transanal Hemorrhoidal Dearterialization With Mucopexy Versus Vessel-Sealing Device Hemorrhoidectomy for Grade III to IV Hemorrhoids: A Prospective Randomized Multicenter Trial. 61
30807456 2019
48
High post-operative pain scores despite multimodal analgesia in ambulatory anorectal surgery: a prospective cohort study. 61
30189793 2019
49
Anti-Inflammatory Effects of Phenolic Compounds Isolated from Quercus Mongolica Fisch. ex Ledeb. on UVB-Irradiated Human Skin Cells. 61
31454971 2019
50
[Effect of electroacupuncture preconditioning combined with induced urination on urinary retention after milligan-morgan hemorrhoidectomy]. 61
31397125 2019

Variations for Hemorrhoid

Expression for Hemorrhoid

Search GEO for disease gene expression data for Hemorrhoid.

Pathways for Hemorrhoid

GO Terms for Hemorrhoid

Cellular components related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 VAT1 MMP9 KLK3 FLNA F2 CRP

Biological processes related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
2 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
3 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Hemorrhoid

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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