MCID: HMR005
MIFTS: 46

Hemorrhoid

Categories: Cardiovascular diseases, Gastrointestinal diseases, Skin diseases

Aliases & Classifications for Hemorrhoid

MalaCards integrated aliases for Hemorrhoid:

Name: Hemorrhoid 12 74 15 17
Hemorrhoids 42 43 15 71
Hemorrhoidal Disease 12
Rectal Diseases 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9746
ICD9CM 34 455
MeSH 43 D006484
NCIt 49 C26792
SNOMED-CT 67 70153002
UMLS 71 C0019112 C0034882

Summaries for Hemorrhoid

MedlinePlus : 42 What are hemorrhoids? Hemorrhoids are swollen, inflamed veins around your anus or the lower part of your rectum. There are two types: External hemorrhoids, which form under the skin around your anus Internal hemorrhoids, which form in the lining of your anus and lower rectum What causes hemorrhoids? Hemorrhoids happen when there is too much pressure on the veins around the anus. This can be caused by Straining during bowel movements Sitting on the toilet for long periods of time Chronic constipation or diarrhea A low-fiber diet Weakening of the supporting tissues in your anus and rectum. This can happen with aging and pregnancy. Frequently lifting heavy objects What are the symptoms of hemorrhoids? The symptoms of hemorrhoids depend on which type you have: With external hemorrhoids, you may have Anal itching One or more hard, tender lumps near your anus Anal pain, especially when sitting Too much straining, rubbing, or cleaning around your anus may make your symptoms worse. For many people, the symptoms of external hemorrhoids go away within a few days. With internal hemorrhoids, you may have Bleeding from your rectum - you would see bright red blood in your stool, on toilet paper, or in the toilet bowl after a bowel movement Prolapse, which is a hemorrhoid that has fallen through your anal opening Internal hemorrhoids are usually not painful unless they are prolapsed. Prolapsed internal hemorrhoids may cause pain and discomfort. How can I treat hemorrhoids at home? You can most often treat your hemorrhoids at home by Eating foods that are high in fiber Taking a stool softener or a fiber supplement Drinking enough fluids every day Not straining during bowel movements Not sitting on the toilet for long periods of time Taking over-the-counter pain relievers Taking warm baths several times a day to help relieve pain. This could be a regular bath or a sitz bath. With a sitz bath, you use a special plastic tub that allows you to sit in a few inches of warm water. Using over-the-counter hemorrhoid creams, ointments, or suppositories to relieve mild pain, swelling, and itching of external hemorrhoids When do I need to see a health care provider for hemorrhoids? You should see your health care provider if you Still have symptoms after 1 week of at-home treatment Have bleeding from your rectum. Hemorrhoids are a common cause of bleeding, but other conditions can also cause bleeding. They include Crohn's disease, ulcerative colitis, colorectal cancer, and anal cancer. So it's important to see your provider to find the cause of the bleeding. How are hemorrhoids diagnosed? To make a diagnosis, your health care provider Will ask about your medical history Will do a physical exam. Often providers can diagnose external hemorrhoids by looking at the area around your anus. Will do a digital rectal exam to check for internal hemorrhoids. For this, the provider will insert a lubricated, gloved finger into the rectum to feel for anything that is abnormal. May do procedures such as an anoscopy to check for internal hemorrhoids What are the treatments for hemorrhoids? If at-home treatments for hemorrhoids don't help you, you may need a medical procedure. There are several different procedures that your provider can do in the office. These procedures use different techniques to cause scar tissue to form in the hemorrhoids. This cuts off the blood supply, which usually shrinks the hemorrhoids. In severe cases, you may need surgery. Can hemorrhoids be prevented? You can help prevent hemorrhoids by Eating foods that are high in fiber Taking a stool softener or a fiber supplement Drinking enough fluids every day Not straining during bowel movements Not sitting on the toilet for long periods of time NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Hemorrhoid, also known as hemorrhoids, is related to internal hemorrhoid and rectal disease, and has symptoms including nausea and vomiting, abdominal pain and constipation. An important gene associated with Hemorrhoid is MMP9 (Matrix Metallopeptidase 9). The drugs Rutin and Glycerol have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and colon.

Disease Ontology : 12 A pelvic varices that is characterized by swollen, inflamed veins around the anus or lower rectum.

Wikipedia : 74 Hemorrhoids, also spelled haemorrhoids, are vascular structures in the anal canal. In their normal... more...

Related Diseases for Hemorrhoid

Diseases in the Hemorrhoid family:

Internal Hemorrhoid

Diseases related to Hemorrhoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 410)
# Related Disease Score Top Affiliating Genes
1 internal hemorrhoid 33.1 VAT1 NOS2 MMP9 FLNA ATP4A ATP12A
2 rectal disease 31.6 KLK3 DCXR CRP CEACAM5 APOLD1 ALB
3 constipation 31.1 NOS2 FLNA CRP ATP4A ATP12A APOLD1
4 malignant anus melanoma 30.9 MLANA APOLD1
5 portal hypertension 30.8 NOS2 F2 ALB
6 anal fistula 30.7 MMP9 MIR6086 MIR1185-1 APOLD1
7 proctitis 30.7 KLK3 CRP APOLD1
8 venous insufficiency 30.6 MMP9 F2 CRP
9 intussusception 30.5 CRP APOLD1 ALB
10 thrombophlebitis 30.5 F2 CRP ALB
11 rectum adenocarcinoma 30.4 DCXR CEACAM5 APOLD1
12 chronic venous insufficiency 30.4 MMP9 F2 CRP
13 esophageal varix 30.4 F2 ATP4A ATP12A ALB
14 fournier gangrene 30.3 F2 ALB
15 dieulafoy lesion 30.3 ATP4A ATP12A APOLD1
16 hernia, hiatus 30.2 CRP ATP4A ATP12A
17 impotence 30.1 NOS2 KLK3 ALB
18 deficiency anemia 30.1 CRP ATP4A ATP12A ALB
19 giardiasis 30.1 ATP4A ATP12A ALB
20 gastroenteritis 30.1 MMP9 CRP ALB
21 functional diarrhea 29.9 ATP4A ATP12A
22 endocarditis 29.8 F2 CRP ALB
23 pleural empyema 29.8 F2 CRP ALB
24 compartment syndrome 29.8 F2 CRP ALB
25 lactose intolerance 29.8 CRP ATP4A ATP12A ALB
26 vascular disease 29.8 NOS2 MMP9 F2 CRP ALB
27 heart valve disease 29.5 F2 CRP ALB
28 volvulus of midgut 29.5 CRP ATP4A ATP12A APOLD1 ALB
29 pulmonary disease, chronic obstructive 29.5 MMP9 CRP ATP4A ATP12A ALB
30 exanthem 29.5 F2 CRP ATP4A ATP12A ALB
31 cholangitis 29.4 F2 CRP CEACAM5 ALB
32 acute cystitis 29.3 KLK3 F2 CRP ALB
33 migraine with or without aura 1 29.0 MMP9 F2 CRP ATP4A ATP12A ALB
34 intestinal obstruction 28.5 FLNA CRP CEACAM5 ATP4A ATP12A APOLD1
35 perianal hematoma 12.0
36 varicose veins 11.7
37 anus disease 11.2
38 thrombosis 10.7
39 hepatic flexure cancer 10.5 DCXR APOLD1
40 pelvic organ prolapse 10.5
41 lentigo maligna melanoma 10.5 MMP9 MLANA
42 vagus nerve disease 10.5 ATP4A ATP12A
43 hemangioma of intra-abdominal structure 10.5 ATP4A ATP12A
44 acquired gastric outlet stenosis 10.5 ATP4A ATP12A
45 displacement of cardia through esophageal hiatus 10.5 ATP4A ATP12A
46 angiodysplasia of intestine 10.5 ATP4A ATP12A
47 benzylpenicillin allergy 10.5 ATP4A ATP12A
48 granulomatous gastritis 10.5 ATP4A ATP12A
49 bacterial esophagitis 10.5 ATP4A ATP12A
50 lingual goiter 10.5 ATP4A ATP12A

Graphical network of the top 20 diseases related to Hemorrhoid:



Diseases related to Hemorrhoid

Symptoms & Phenotypes for Hemorrhoid

UMLS symptoms related to Hemorrhoid:


nausea and vomiting, abdominal pain, constipation, diarrhea, icterus, rectal tenesmus, dyspepsia, heartburn, pruritus ani, gastrointestinal gas, rectal pain

Drugs & Therapeutics for Hemorrhoid

Drugs for Hemorrhoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 198)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rutin Approved, Experimental, Investigational Phase 4 153-18-4 5280805
2
Glycerol Approved, Investigational Phase 4 56-81-5 753
3
Menthol Approved Phase 4 2216-51-5 16666
4
Borage oil Approved, Investigational Phase 4
5
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
7
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
8
Prilocaine Approved Phase 4 721-50-6 4906
9
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
10
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
11
Morphine Approved, Investigational Phase 4 57-27-2 5288826
12
Polidocanol Approved Phase 4 9002-92-0
13
Metronidazole Approved Phase 4 443-48-1 4173
14
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
15
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
16
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
17
tannic acid Approved Phase 4 1401-55-4
18
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
19
Estazolam Approved, Illicit Phase 4 29975-16-4 3261
20
Ethanol Approved Phase 4 64-17-5 702
21
Mineral oil Approved, Vet_approved Phase 4 8042-47-5
22
Acetaminophen Approved Phase 4 103-90-2 1983
23
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
24
Ibuprofen Approved Phase 4 15687-27-1 3672
25
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
26
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
27
Magnesium oxide Approved Phase 4 1309-48-4 14792
28
Lactulose Approved Phase 4 4618-18-2 11333
29
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
30 Lecithin Phase 4
31 Aloe Phase 4
32 Soy Bean Phase 4
33 Devil's Claw Phase 4
34 Arnica Phase 4
35 Gotu Kola Phase 4
36 Borage Phase 4
37 Fibrinolytic Agents Phase 4
38 Platelet Aggregation Inhibitors Phase 4
39 Calcium Dobesilate Phase 4
40 Sodium Channel Blockers Phase 4
41 Anti-Arrhythmia Agents Phase 4
42 Diuretics, Potassium Sparing Phase 4
43 abobotulinumtoxinA Phase 4
44 Cholinergic Agents Phase 4
45 Botulinum Toxins, Type A Phase 4
46 Botulinum Toxins Phase 4
47 Analgesics, Non-Narcotic Phase 4
48 Cyclooxygenase Inhibitors Phase 4
49 Anti-Inflammatory Agents, Non-Steroidal Phase 4
50 Sclerosing Solutions Phase 4

Interventional clinical trials:

(show top 50) (show all 196)
# Name Status NCT ID Phase Drugs
1 Prospective and Randomized Trial Comparing Dopplper-Guided Transanal Hemorrhoid Artery Ligation With Recto-anal Repair (HAL-RAR) Versus Excisional Hemorrhoidectomy for the Treatment of Grade III-IV Hemorrhoids Unknown status NCT02216305 Phase 4
2 Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy: A Randomized Double-blind Controlled Trial Unknown status NCT01099605 Phase 4
3 Irritation and Anal Bleeding in Patients Affected by Hemorrhoids: Comparative Evaluation of Three Different Treatments. Unknown status NCT03569930 Phase 4 flavonoid-based supplements;Centella Complex
4 The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Continuing or Discontinuing on Aspirin: a Multicenter, Double-blind, Placebo-controlled, Randomized Clinical Trial Unknown status NCT01549418 Phase 4 Aspirin (ASA);Placebo
5 Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease a Randomised Triple Blind Controlled Trial Completed NCT02782455 Phase 4 Flavonoids;CDobi
6 A Comparative Clinical Research on Therapeutic Effect and Safety of Compound Carraghenates Cream Versus Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids Completed NCT01881282 Phase 4 Carraghenates Cream;Mayinglong Musk Hemorrhoid Ointment
7 Prospective Randomized Trial on Surgical Treatment of Grade 3 Hemorrhoids: Hemorrhoidectomy Versus Doppler-guided Transanal Haemorrhoidal Dearterialisation and Anopexy Completed NCT01263431 Phase 4
8 Randomized Clinical Trial of Botulinum Toxin Injection for Pain Relief in Patients With Thrombosed External Haemorrhoids Completed NCT00717782 Phase 4
9 The Comparison of the Discharge Conditions and Efficacy of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl in Outpatient Minor Perianal Surgery Completed NCT01880775 Phase 4 Prilocaine;Bupivacaine
10 Symptom Control 1-year After Circular Stapler Anopey or Diathermy Excision for Prolapsed Haemorrhoids: an International Randomsed Trial (the STOPP-trial Completed NCT00841620 Phase 4
11 Effect of Perioperative i.v. Low-dose S(+) Ketamine in Patients Undergoing Hemorrhoidectomy Completed NCT00354029 Phase 4 S (+) Ketamine;Placebo
12 Perianal Nerval Block in Proctological Interventions: a Prospective Randomized Double Blinded Study Completed NCT03405922 Phase 4 Placebo 40 mL Saline 0.9%;40 mL Ropivacain 0.5%
13 Double-blinded Multicenter Randomized Clinical Trial to Evaluate the Efficacy and Safety of CLIFE1 and CLIFE2 Gels in Benign Anorectal Surgery Completed NCT02961855 Phase 4 anesthesics plus antiinflammatory, CLIFE1;local anesthesics, CLIFE2
14 Assessment of the Analgesic Efficacy of Morphine Chloride in Addition to a Low Dose Solution of Spinal Anaesthetic in Hemorrhoidectomy Compared to a Standard Dose of Spinal Local Anaesthetic. Simple Blind, Randomized, With Blinded Evaluation by Third Parties Clinical Trial. Completed NCT02046772 Phase 4 Bupivacaine low dose;Bupivacaine standard dose;Morphine Chloride
15 Comparing the Effects of Levobupivacaine and Bupivacaine in Anorectal Surgery Under Saddle Spinal Anesthesia Completed NCT04245774 Phase 4 Levobupivacaine (as Levobupivacaine Hydrochloride) 75 Mg/10 mL Solution for Injection Ampoule;Bupivacaine/Dextrose
16 A Multicenter Prospective Clinical Study of Endoscopic Foam Sclerotherapy for Internal Hemorrhoids Recruiting NCT04398823 Phase 4 Sclerosing foam of Lauromacrogol;Sclersing liqiud of Lauromacrogol
17 Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial. Recruiting NCT04248205 Phase 4 Ketamine
18 A Prospective, Multicentre, Double-Blinded Randomised Controlled Trial Comparing Topical Versus Oral Metronidazole in Reducing Post-Operative Pain Following Excisional Haemorrhoidectomy Recruiting NCT03343509 Phase 4 Metronidazole Oral;Metronidazole Ointment;Placebo Oral Tablet;Placebo Ointment
19 The First Affiliated Hospital of Guangzhou University of Chinese Medicine Recruiting NCT03997058 Phase 4 Oral estazolam medication
20 Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery Recruiting NCT03738904 Phase 4
21 Comparison of Rectal Infiltration of Exparel vs. 0.25% Bupivacaine With Epinephrine vs. Placebo for Analgesic Benefit Following Hemorrhoidectomy Terminated NCT02104414 Phase 4 Exparel;Bupivacaine HCl with Epinephrine;Normal Saline
22 An Open, Randomized, Parallel Group, Single Center Study to Investigate the Effect of Lactulose Versus Plantago Ovate on the Quality of Life of Patients With Hard Stools and Hemorrhoids or Anal Fissure Terminated NCT00160290 Phase 4 Lactulose;Plantago ovata
23 Local vs General Anaesthesia in Stapled Hemorrhoidectomy: A Multicentric Controlled Randomized Trial Withdrawn NCT00512044 Phase 4
24 Multi-drug Analgesia Versus Standard Solution for Perianal Block - A Prospective Study to Determine the Efficacy, Cost and Narcotic Consumption in the Post-operative Period Withdrawn NCT03105674 Phase 4 Multi-drug local anesthetics (Combination);Standard local anesthetics (Combination)
25 Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills Unknown status NCT00861562 Phase 3 Imescard water smartweed composed pills;Placebo
26 Phase 3 Clinical Trial - Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed, Adrenalin and Hamamelis Ointment Unknown status NCT00935948 Phase 3 Imescard compound water smartweed ointment;Placebo
27 Prospective Randomized Trial Comparing Transanal Doppler de-Arterialization (THD) Versus Stapler Operation for 3rd Degree Hemorrhoids Unknown status NCT00823784 Phase 3
28 Double Blinded Randomized Clinical Trial of the Efficacy of Topical 2% Lidocaine for the Treatment of Symptomatic Hemorrhoids Unknown status NCT01961739 Phase 2, Phase 3 2% lidocaine;placebo
29 Study Clinical, Multicenter,Phase III,Prospective,Randomized,Comparative Double Blind/Double-dummy to Assess the Efficacy and Tolerability of the Use of Varicell in Reducing the Symptoms Caused by Chronic Venous Insufficiency and Hemorrhoidal Syndrome When Compared With Daflon Unknown status NCT01321619 Phase 3 Daflon;Varicell placebo
30 Randomized Controlled Trials of Diet and Lifestyle Intervention to Promote Chinese Postpartum Women's Health Unknown status NCT01039051 Phase 2, Phase 3
31 Patient Comfort After Stapled Hemorrhoidopexy Long Term Results of a Randomized Controlled Trial Completed NCT01533363 Phase 3
32 A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Safety and Efficacy of a Single Administration of SKY0402 for Prolonged Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Completed NCT00890721 Phase 3 SKY0402;Placebo
33 Topical Anesthesia Versus Placebo to Decrease Post Procedure Pain in Rubber Band Ligation for the Treatment of Grade I - III Symptomatic Internal Hemorrhoids. A Single Institution, Double Blinded, Placebo Controlled Trial. Completed NCT02130830 Phase 3 Topical 2,5% lidocaine + 2,5% prilocaine gel;Placebo
34 A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3 Completed NCT02010099 Phase 2, Phase 3 PP110 Gel;PP110 Medicated wipes;Preparation-H Cream
35 Effectiveness of Metronidazole Versus Homologated Placebo in Pain Control Posthemorrhoidectomy Completed NCT02328144 Phase 3 Metronidazole;Placebo
36 Safety and Short Term Effectiveness of EEA Stapler vs PPH Stapler in the Treatment of III Degree Haemorrhoids. Prospective Randomized Controlled Trial Completed NCT01413867 Phase 3
37 Phase 3, Multicenter, Randomized, Double-Blind, Parallel-group, Active-control Study to Evaluate the Safety and Efficacy of a Single Administration of SKY0402 for Prolonged Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Completed NCT00744848 Phase 3 Bupivacaine HCl;SKY0402
38 Pudendal Nerve Block in Patient Treated for Hemorrhoidectomy Under Spinal Anaesthesia: Prospective Randomized Double-blind Controlled Trial Completed NCT04251884 Phase 3
39 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Budesonide Foam (2 mg/25 mL BID for 2 Weeks, Followed by 2 mg/25 mL QD for 4 Weeks) Versus Placebo in Subjects With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis Completed NCT01008423 Phase 3 Budesonide;Placebo
40 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Budesonide Foam (2 mg/25 mL BID for 2 Weeks, Followed by 2 mg/25 mL QD for 4 Weeks) Versus Placebo in Subjects With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis Completed NCT01008410 Phase 3 Budesonide;Placebo
41 Randomized Trial Comparing Drainage Versus no Drainage Following Rectal Excision With Low Anastomosis for Rectal Cancer Completed NCT01269567 Phase 3
42 Aquanet Bowel Cleansing Device Versus Oral Sodium Picosulfate for Pre-endoscopy Bowel Preparation: Propensity Score Analysis for Interventional Effectiveness Evaluation Completed NCT03074448 Phase 3 Sodium Picosulfate
43 Sclerotherapy With Polidocanol Foam In The Management Of First, Second And Third-Grade Hemorrhoidal Disease In Patients With Bleeding Disorders: A Prospective Cohort Study Recruiting NCT04188171 Phase 2, Phase 3
44 A Randomised Controlled Trial Comparing Conventional Open Haemorrhoidectomy and Laser Haemorrhoidoplasty in the Treatment of Symptomatic Haemorrhoids: COHLAH Trial Recruiting NCT04329364 Phase 2, Phase 3
45 Impact of Topical Antiadhesion Therapy on Wound Healing and Postoperative Pain After Anal Surgery: A Randomized Double-blinded Controlled Study Recruiting NCT04275596 Phase 3 2QR complex;Placebo
46 A Phase 3 Study of BBI-608 in Combination With 5-Fluorouracil, Leucovorin, Irinotecan (FOLFIRI) in Adult Patients With Previously Treated Metastatic Colorectal Cancer (CRC). Active, not recruiting NCT02753127 Phase 3 Napabucasin;Fluorouracil;Leucovorin;Irinotecan;Bevacizumab
47 A Multi-arm Randomized Clinical Trial on Combination Topical Analgesia Post-haemorrhoidectomy: a Study on Metronidazole, Diltiazem and Lignocaine. Not yet recruiting NCT04276298 Phase 2, Phase 3 Metronidazole cream;Combination Metronidazole, Diltiazem and Lignocaine
48 Topical Endorectal Vietamin E Ovules for the Treatment of Grade 2 and 3 Hemorrhoids Not yet recruiting NCT04362384 Phase 3 Vitamin E ovules;Prednisolone ointment
49 A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of Intra-Anal Application of Iferanserin (10 mg) as a 0.5% Ointment in Subjects With Symptomatic Internal Hemorrhoids Terminated NCT01355874 Phase 3 Iferanserin;Placebo;Iferanserin + Placebo
50 A Phase 3, Open Label, Multicenter Study to Assess the Safety and Tolerability of Budesonide Foam in Subjects With Active Ulcerative Proctitis or Proctosigmoiditis Terminated NCT01349673 Phase 3 Budesonide Foam

Search NIH Clinical Center for Hemorrhoid

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Benzocaine
BENZOCAINE PWDR
Hydrocortisone
hydrocortisone acetate
HYDROCORTISONE ACETATE PWDR
HYDROCORTISONE ACETONIDE
Hydrocortisone butyrate
hydrocortisone cypionate
hydrocortisone probutate
HYDROCORTISONE PWDR
Hydrocortisone sodium phosphate
Hydrocortisone sodium succinate
hydrocortisone valerate
HYDROCORTISONE,NONSTERILE PWDR
Phenylephrine
Phenylephrine bitartrate
Phenylephrine Hydrochloride
Phenylephrine Tannate
pramoxine
Pramoxine hydrochloride
Psyllium
PSYLLIUM HYDROCOLLOID
Witch Hazel

Cochrane evidence based reviews: hemorrhoids

Genetic Tests for Hemorrhoid

Anatomical Context for Hemorrhoid

MalaCards organs/tissues related to Hemorrhoid:

40
Skin, Testes, Colon, Prostate, Liver, Kidney, Spinal Cord

Publications for Hemorrhoid

Articles related to Hemorrhoid:

(show top 50) (show all 3175)
# Title Authors PMID Year
1
Traditional Chinese medicine (Liang-Xue-Di-Huang Decoction) for hemorrhoid hemorrhage: Study Protocol Clinical Trial (SPIRIT Compliant). 61 42
32311960 2020
2
Hemorrhoidal artery ligation with Doppler guidance vs digital guidance for grade II-III hemorrhoidal disease treatment: Study protocol clinical trial (SPIRIT Compliant). 42
32282696 2020
3
Comparative study of endoscopic band ligation versus injection sclerotherapy with 50% dextrose in water, in symptomatic internal haemorrhoids. 42
32003357 2020
4
Preoperative bleeding requiring transfusion: An under-reported indication for hemorrhoidectomy. 61
31932077 2020
5
Hemorrhoidectomy for elderly patients aged 75 years or more, before and after studies. 61
32477502 2020
6
Transanal hemorrhoidal dearterialization: Lessons learned from a personal series of 200 consecutive cases and a proposal for a tailor-made procedure. 61
32518642 2020
7
A Primary Large Anorectal Melanoma That Causes Intermittent Rectal Bleeding and Appears as a Hemorrhoid. 61
30710702 2020
8
Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer. 61
32166451 2020
9
Thunderbeat-Assisted Hemorrhoidectomy in Symptomatic Prolapsing Hemorrhoids: A Pilot Trial. 61
32146865 2020
10
The Italian paradox of flavonoid use for hemorrhoids. 61
32303928 2020
11
Predictive factors of rectal hemorrhage in patients with localized prostate cancer who underwent low-dose-rate brachytherapy. 61
32500469 2020
12
Endoscopic Findings in Patients Under the Age of 40 Years with Hematochezia in Singapore. 61
32549525 2020
13
Contributions of Avicenna to surgery and anesthesiology. 61
32013741 2020
14
Rubber Band Ligation of Hemorrhoids is often a Necessary Complement in the Management of Hemorrhagic Radiation Proctitis. 61
30632450 2020
15
Croton urucurana Baillon stem bark ointment accelerates the closure of cutaneous wounds in knockout IL-10 mice. 61
32531412 2020
16
Micronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis. 61
32399811 2020
17
Fungating Anal Mass: Extrapulmonary Small Cell Carcinoma Masquerading as a Hemorrhoid. 61
31848872 2020
18
Implementation of General Surgery Care into a Student-Run Free Clinic. 61
32543381 2020
19
Polidocanol versus phenol in oil injection sclerotherapy in treatment of internal hemorrhoids: A randomized controlled trial. 61
32519957 2020
20
Comparison of Centella with Flavonoids for Treatment of Symptoms in Hemorrhoidal Disease and After Surgical Intervention: A Randomized Clinical Trial. 61
32409760 2020
21
The management of Hemorrhoidal Disease by Dearterialization and Mucopexy. 61
32370723 2020
22
Minimal Open Hemorrhoidectomy Versus Transanal Hemorrhoidal Dearterialization: The Effect on Symptoms: An Open-Label Randomized Controlled Trial. 61
31996581 2020
23
A Rare Clinical Presentation of Metastatic Crohn's Disease. 61
32467818 2020
24
Mucopexy-Recto Anal Lifting (MuRAL) in managing obstructed defecation syndrome associated with prolapsed hemorrhoids and rectocele: preliminary results. 61
32411633 2020
25
YouTube as a source of patients and specialists' information on hemorrhoids and hemorrhoid surgery. 61
32448106 2020
26
Assessment of pediatric Crohn's disease activity: validation of the magnetic resonance enterography global score (MEGS) against endoscopic activity score (SES-CD). 61
32458027 2020
27
Chronic Constipation in the Community: A National Survey of Australian Adults. 61
32332586 2020
28
Physiological 18F-FDG uptake in the normal adult anal canal: evaluation by PET/CT. 61
32430619 2020
29
A rare case of musk anti-hemorrhoids ointment-induced symmetrical drug-related intertriginous and flexural exanthema. 61
32333604 2020
30
Recovery from hemorrhoids and anal fissure without surgery. 61
32412899 2020
31
Expert Commentary on the Evaluation and Management of Hemorrhoids. 61
32132464 2020
32
Early and late effects of the sequential transfixed stich technique for the treatment of the symptomatic rectocele without rectal mucosa prolapse. 61
32009331 2020
33
Short-Term Results of Sclerotherapy with 3% Polidocanol Foam for Symptomatic Second- and Third-Degree Hemorrhoidal Disease. 61
32290709 2020
34
Off-label prescribing during pregnancy in France: the NéHaVi cohort
. 61
31933473 2020
35
Post Hemorrhoidectomy Pain Management: The Latest News. 61
32250232 2020
36
Hemorrhoidal Laser procedure (HeLP) and Hemorrrrhoidal Laser procedure + mucopexy (HeLPexx) and other Emerging Technologies. 61
32250230 2020
37
Evaluation and Management of Hemorrhoids. 61
32132463 2020
38
Phytochemical Diversity and Pharmacological Properties of Rhus coriaria. 61
32141706 2020
39
Rectal bleeding caused by iatrogenic ulceration after hemorrhoid ligation. 61
32107683 2020
40
[Differential diagnosis of hemorrhoidal disease]. 61
32077979 2020
41
Fundamentals of Anorectal Technical Skills: A Concise Surgical Skills Course. 61
32313930 2020
42
Lower Gastrointestinal Bleeding in Patients With Cirrhosis-Etiology and Outcomes. 61
32087941 2020
43
POSTOPERATIVE COMPLICATIONS IN HEMORRHOIDAL DISEASE AND SPECIAL CONDITIONS. 61
32250228 2020
44
Management of Hemorrhoidal Disease in Special Conditions: A Word of Caution. 61
32250231 2020
45
Hemorrhoidal disease and chronic venous insufficiency: Concomitance or coincidence; results of the CHORUS study (Chronic venous and HemORrhoidal diseases evalUation and Scientific research). 61
31512275 2020
46
Post hemorrhoidectomy complications: CT imaging findings. 61
31927497 2020
47
External hemorrhoidal thrombosis in the elderly patients: conservative and surgical management. 61
30600960 2020
48
Results of the double-blind randomized controlled trial comparing laser hemorrhoidoplasty with sutured mucopexy and excisional hemorrhoidectomy. 61
31912268 2020
49
Anorectal Functional Outcomes Following Doppler-Guided Transanal Hemorrhoidal Dearterialization: Evidence from Vietnam. 61
31997241 2020
50
Scoring System for Haemorrhoidal Disease. 61
32189598 2020

Variations for Hemorrhoid

Expression for Hemorrhoid

Search GEO for disease gene expression data for Hemorrhoid.

Pathways for Hemorrhoid

GO Terms for Hemorrhoid

Cellular components related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 VAT1 MMP9 KLK3 FLNA F2 CRP

Biological processes related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
2 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Hemorrhoid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Hemorrhoid

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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