MCID: HNC001
MIFTS: 62

Henoch-Schoenlein Purpura

Categories: Blood diseases, Bone diseases, Cardiovascular diseases, Immune diseases, Nephrological diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Henoch-Schoenlein Purpura

MalaCards integrated aliases for Henoch-Schoenlein Purpura:

Name: Henoch-Schoenlein Purpura 12 15 17 74
Henoch-Schonlein Purpura 12 54 56
Immunoglobulin a Vasculitis 54 60
Henoch-Schönlein Purpura 77 60
Anaphylactoid Purpura 54 60
Iga Vasculitis 60 38
Immunoglobulin-a Vasculitis 54
Purpura, Schoenlein-Henoch 45
Purpura, Schönlein-Henoch 77
Purpura, Schonlein-Henoch 54
Henoch-Sch@nlein Purpura 12
Henoch Schonlein Purpura 54
Henoch-Schnlein Purpura 12
Henoch-Scholein Purpura 12
Purpura, Autoimmune 12
Autoimmune Purpura 12
Purpura Rheumatica 60
Rheumatoid Purpura 60
Allergic Purpura 12
Vascular Purpura 54

Characteristics:

Orphanet epidemiological data:

60
immunoglobulin a vasculitis
Inheritance: Not applicable; Age of onset: Childhood; Age of death: any age;

Classifications:



Summaries for Henoch-Schoenlein Purpura

NIH Rare Diseases : 54 Henoch-Schonlein purpura (HSP), also called immunoglobulin A vasculitis (IgAV), is a vascular disease that primarily affects small blood vessels. The disease is characterized by abnormal deposits of immunoglobulin A (an antibody) in the blood vessels, leading to their inflammation (vasculitis). The small vessels of the skin, joints, kidneys, and digestive organs are particularly involved. Signs and symptoms usually begin suddenly (and progress over days) and may include purple-colored spots on the skin (purpura); joint pain; and gastrointestinal problems such as abdominal pain, nausea, bloody stools, and rarely, severe complications requiring surgery. People with HSP may also develop glomerulonephritis (injury to the kidneys caused by inflammation) and poor kidney function, which may result in swelling of parts of the body or face (edema), and blood and protein in the urine (hematuria and proteinuria). Most cases of HSP occur in children and go away without causing serious or long-term health problems. Less commonly, the disease affects adults and may be more severe, leading to chronic kidney disease and kidney failure. The cause of HSP is not completely understood, but research indicates that genes (especially those involved in regulating the immune system) may play a key role in predisposing a person to HSP, as well as its severity. However, while genes may increase the risk of developing the disease (and in some cases more than one family member has HSP), the disease itself is not inherited. Environmental �??triggers�?� such as foods, infections, or medications may also play a role in the onset of the disease. The diagnosis of HSP may be made based on symptoms, blood and urine tests, imaging studies, and/or a biopsy of the skin or kidney. Most cases go away within several weeks without treatment. When needed, treatment aims to relieve symptoms and may include medications for pain and inflammation. People with chronic kidney involvement or advanced kidney disease may require immunosuppressive medications, hemodialysis, or kidney transplantation. The long-term outlook depends on the extent of kidney involvement. Rarely, HSP is fatal due to kidney complications. In some cases, the disease recurs, sometimes more than once.

MalaCards based summary : Henoch-Schoenlein Purpura, also known as henoch-schonlein purpura, is related to arteries, anomalies of and mononeuritis multiplex. An important gene associated with Henoch-Schoenlein Purpura is VCAM1 (Vascular Cell Adhesion Molecule 1), and among its related pathways/superpathways are Innate Immune System and Selenium Micronutrient Network. The drugs Prednisone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and testes, and related phenotypes are nausea and vomiting and arthralgia

Disease Ontology : 12 A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection.

Wikipedia : 77 Henoch–Schönlein purpura (HSP) is a disease of the skin, mucous membranes, and sometimes other organs... more...

Related Diseases for Henoch-Schoenlein Purpura

Diseases related to Henoch-Schoenlein Purpura via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 300)
# Related Disease Score Top Affiliating Genes
1 arteries, anomalies of 30.7 CRP ICAM1 VCAM1
2 mononeuritis multiplex 30.6 CRP MPO
3 polyarteritis nodosa 30.6 CRP MEFV MPO
4 crescentic glomerulonephritis 30.6 ICAM1 MPO VCAM1
5 rapidly progressive glomerulonephritis 30.5 CRP ICAM1 MPO
6 glomerulonephritis 30.4 C3 CD79A ICAM1 MPO VCAM1
7 vasculitis 30.3 CRP ICAM1 MEFV MPO VCAM1
8 peritonitis 30.3 CRP ICAM1 MEFV MPO
9 myeloma, multiple 30.1 CD79A CRP HSP90AA1
10 membranoproliferative glomerulonephritis 30.0 C3 CD79A ICAM1
11 malaria 29.7 CRP HSP90AA1 ICAM1 VCAM1
12 systemic lupus erythematosus 29.7 C3 CD79A CRP ICAM1 MPO VCAM1
13 hypersensitivity vasculitis 28.4 C1GALT1 C3 CD79A CRP HSP90AA1 MEFV
14 thrombocytopenic purpura, autoimmune 12.6
15 thrombotic thrombocytopenic purpura, acquired 11.6
16 immunodeficiency, common variable, 8, with autoimmunity 11.3
17 thrombocytopenia due to platelet alloimmunization 11.2
18 purpura 11.1
19 intussusception 10.6
20 iga glomerulonephritis 10.5
21 arthritis 10.5
22 testicular torsion 10.5
23 ulcerative colitis 10.5
24 lymphoma 10.4
25 brucellosis 10.4
26 nephrotic syndrome 10.4
27 pancreatitis 10.4
28 lymphocytic vasculitis 10.4 ICAM1 VCAM1
29 microvascular complications of diabetes 3 10.4
30 microvascular complications of diabetes 4 10.4
31 microvascular complications of diabetes 6 10.4
32 microvascular complications of diabetes 7 10.4
33 hemorrhage, intracerebral 10.4
34 cortical thymoma 10.4 ICAM1 VCAM1
35 mooren's ulcer 10.4 ICAM1 VCAM1
36 coronary artery anomaly 10.4
37 lupus erythematosus 10.4
38 sinusitis 10.3 LTC4S RNASE3
39 shwartzman phenomenon 10.3 ICAM1 VCAM1
40 subendocardial myocardial infarction 10.3 ICAM1 VCAM1
41 actinic prurigo 10.3 ICAM1 VCAM1
42 brachydactyly, type e2 10.3 ICAM1 VCAM1
43 maxillary sinusitis 10.3 MPO RNASE3
44 monoclonal paraproteinemia 10.3 HSP90AA1 MPO
45 rheumatoid vasculitis 10.3 ICAM1 VCAM1
46 acute proliferative glomerulonephritis 10.3 ICAM1 MPO
47 limbal stem cell deficiency 10.3 ICAM1 VCAM1
48 helicobacter pylori infection 10.3
49 polyarteritis nodosa, childhood-onset 10.3
50 pulmonary tuberculosis 10.3

Graphical network of the top 20 diseases related to Henoch-Schoenlein Purpura:



Diseases related to Henoch-Schoenlein Purpura

Symptoms & Phenotypes for Henoch-Schoenlein Purpura

Human phenotypes related to Henoch-Schoenlein Purpura:

60 33 (show all 34)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 nausea and vomiting 60 33 hallmark (90%) Very frequent (99-80%) HP:0002017
2 arthralgia 60 33 hallmark (90%) Very frequent (99-80%) HP:0002829
3 abdominal pain 60 33 hallmark (90%) Very frequent (99-80%) HP:0002027
4 hematuria 60 33 hallmark (90%) Very frequent (99-80%) HP:0000790
5 purpura 60 33 hallmark (90%) Very frequent (99-80%) HP:0000979
6 skin rash 60 33 hallmark (90%) Very frequent (99-80%) HP:0000988
7 bruising susceptibility 60 33 hallmark (90%) Very frequent (99-80%) HP:0000978
8 vasculitis 60 33 hallmark (90%) Very frequent (99-80%) HP:0002633
9 gastrointestinal infarctions 60 33 hallmark (90%) Very frequent (99-80%) HP:0005244
10 pustule 60 33 hallmark (90%) Very frequent (99-80%) HP:0200039
11 encephalitis 60 33 frequent (33%) Frequent (79-30%) HP:0002383
12 arthritis 60 33 frequent (33%) Frequent (79-30%) HP:0001369
13 fever 60 33 frequent (33%) Frequent (79-30%) HP:0001945
14 skin ulcer 60 33 frequent (33%) Frequent (79-30%) HP:0200042
15 anorexia 60 33 frequent (33%) Frequent (79-30%) HP:0002039
16 migraine 60 33 frequent (33%) Frequent (79-30%) HP:0002076
17 myalgia 60 33 frequent (33%) Frequent (79-30%) HP:0003326
18 erythema 60 33 frequent (33%) Frequent (79-30%) HP:0010783
19 orchitis 60 33 frequent (33%) Frequent (79-30%) HP:0100796
20 seizures 60 33 occasional (7.5%) Occasional (29-5%) HP:0001250
21 muscle weakness 60 33 occasional (7.5%) Occasional (29-5%) HP:0001324
22 optic atrophy 60 33 occasional (7.5%) Occasional (29-5%) HP:0000648
23 renal insufficiency 60 33 occasional (7.5%) Occasional (29-5%) HP:0000083
24 proteinuria 60 33 occasional (7.5%) Occasional (29-5%) HP:0000093
25 hemiplegia/hemiparesis 60 33 occasional (7.5%) Occasional (29-5%) HP:0004374
26 glomerulopathy 60 33 occasional (7.5%) Occasional (29-5%) HP:0100820
27 gastrointestinal hemorrhage 60 33 occasional (7.5%) Occasional (29-5%) HP:0002239
28 macule 60 33 occasional (7.5%) Occasional (29-5%) HP:0012733
29 urticaria 60 33 occasional (7.5%) Occasional (29-5%) HP:0001025
30 restrictive deficit on pulmonary function testing 60 33 occasional (7.5%) Occasional (29-5%) HP:0002111
31 episcleritis 60 33 occasional (7.5%) Occasional (29-5%) HP:0100534
32 angioedema 60 33 occasional (7.5%) Occasional (29-5%) HP:0100665
33 vascular skin abnormality 60 Frequent (79-30%)
34 edema 60 Occasional (29-5%)

MGI Mouse Phenotypes related to Henoch-Schoenlein Purpura:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.5 C1GALT1 C3 CRP ICAM1 LTC4S MPO
2 immune system MP:0005387 9.32 C1GALT1 C3 CD79A CRP HSP90AA1 ICAM1

Drugs & Therapeutics for Henoch-Schoenlein Purpura

Drugs for Henoch-Schoenlein Purpura (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 109)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 53-03-2 5865
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 83-43-2 6741
3
Methylprednisolone hemisuccinate Approved Phase 4,Phase 2,Not Applicable 2921-57-5
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Not Applicable 22916-47-8 4189
5
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 2,Not Applicable 302-25-0
6
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 50-24-8 5755
7
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
8
Prednisolone hemisuccinate Experimental Phase 4,Phase 2,Not Applicable 2920-86-7
9 Anti-Inflammatory Agents Phase 4,Phase 1,Phase 2,Not Applicable
10 Hormones Phase 4,Phase 1,Phase 2,Not Applicable
11 Immunosuppressive Agents Phase 4,Phase 2,Not Applicable
12 Antineoplastic Agents, Hormonal Phase 4,Phase 1,Phase 2,Not Applicable
13 Hormone Antagonists Phase 4,Phase 1,Phase 2,Not Applicable
14 Immunologic Factors Phase 4,Phase 2,Not Applicable
15 Calcineurin Inhibitors Phase 4,Not Applicable
16 glucocorticoids Phase 4,Phase 1,Phase 2,Not Applicable
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 1,Phase 2,Not Applicable
18 Protective Agents Phase 4,Phase 1,Phase 2,Not Applicable
19 Antirheumatic Agents Phase 4,Phase 2,Not Applicable
20 Gastrointestinal Agents Phase 4,Phase 2,Not Applicable
21 Cyclosporins Phase 4,Not Applicable
22 Neuroprotective Agents Phase 4,Phase 2,Not Applicable
23 Antifungal Agents Phase 4,Not Applicable
24 Dermatologic Agents Phase 4,Not Applicable
25 Antiemetics Phase 4,Phase 2,Not Applicable
26 Methylprednisolone Acetate Phase 4,Phase 2,Not Applicable
27 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
28 Autonomic Agents Phase 4,Phase 2,Not Applicable
29 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
30 Prednisolone acetate Phase 4,Phase 2,Not Applicable
31 Omega 3 Fatty Acid Phase 4
32
Cyclophosphamide Approved, Investigational Phase 2,Not Applicable 6055-19-2, 50-18-0 2907
33
Mycophenolic acid Approved Phase 2,Not Applicable 24280-93-1 446541
34
Dalteparin Approved Phase 1, Phase 2 9005-49-6
35
Heparin Approved, Investigational Phase 1, Phase 2 9005-49-6 772 46507594
36
Dipyridamole Approved Phase 1, Phase 2 58-32-2 3108
37
Benazepril Approved, Investigational Phase 1, Phase 2,Phase 2 86541-75-5 5362124
38
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
39
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
40
Leflunomide Approved, Investigational Phase 2 75706-12-6 3899
41
leucovorin Approved Phase 2 58-05-9 6006 143
42
Dapsone Approved, Investigational Phase 2 80-08-0 2955
43
Azathioprine Approved Phase 2 446-86-6 2265
44
Colchicine Approved Phase 2 64-86-8 6167 2833
45
Calcium Approved, Nutraceutical Phase 1, Phase 2 7440-70-2 271
46
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
47 Immunoglobulins Phase 2,Not Applicable
48 Antibodies Phase 2,Not Applicable
49 Alkylating Agents Phase 2,Not Applicable
50 Antineoplastic Agents, Alkylating Phase 2,Not Applicable

Interventional clinical trials:

(show all 28)
# Name Status NCT ID Phase Drugs
1 Tacrolimus in Children With Henoch-Schönlein Purpura Nephritis Completed NCT03222687 Phase 4 tacrolimus;prednisone
2 HSP-glomerulonephritis Trial: MP vs CyA Completed NCT00425724 Phase 4 Methylprednisolone pulses plus prednisone versus Cyclosporine A
3 Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels Terminated NCT00578578 Phase 4
4 Research on the Blood- Cooling - Toxin - Removing - Stasis - Dispersing Protocol Evaluation of Hench-schonlein Purpura Unknown status NCT01104428 Phase 2 Placebo;"ziying" granules
5 Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment Recruiting NCT03591471 Phase 1, Phase 2 Glycosides Of Tripterygium Wilfordii Hook(GTW);Sulfotanshinone Sodium Injection;Chinese herbs based on syndrome differentiation;Prednisone Acetate Tablets;Benazepril Hydrochloride Tablets;Low Molecular Weight Heparin Calcium Injection;Dipyridamole Tab 25 MG;Chinese medicine placebo
6 The Research of Standard Diagnosis and Treatment for Severe HSP in Children Recruiting NCT02540720 Phase 2 Dexamethasone;Gamma globulin
7 The Research of Standard Diagnosis and Treatment for HSPN in Children Recruiting NCT02532777 Phase 2 Prednisone;Cyclophosphamide(CTX);Mycophenolate mofetil(MMF);Leflunomide(LEF);Angiotensin-converting enzyme inhibitor(ACEI);Methylprednisolone
8 The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in Children Recruiting NCT02532790 Phase 2 Prednisone;ACEI
9 A Randomized Multicenter Study for Isolated Skin Vasculitis Recruiting NCT02939573 Phase 2 Colchicine;Dapsone;Azathioprine
10 Identification of Biomarkers Predictive of Worse Prognosis in Henoch Schonlein Purpura Unknown status NCT01610830
11 Interest to Perform a Renal Biopsy Early in the Course of the Henoch-Schoenlein Nephritis Unknown status NCT02811770
12 IgA-positive Versus IgA-negative Immune Complex Vasculitis Unknown status NCT01815190
13 Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Unknown status NCT00006055 Not Applicable anti-thymocyte globulin;cyclophosphamide;cyclosporine;filgrastim;methylprednisolone;prednisone
14 Study of the Role of Regulator T Cells in the Pathophysiology of Childhood Henoch Schönlein Purpura Completed NCT02317133
15 Efficacy of Steroid Versus Steroid Plus Cyclophosphamide for Severe Henoch-Schoenlein Purpura Completed NCT00190229 Not Applicable Cyclophosphamide
16 Mycophenolate Mofetil (MMF) Versus Intravenous CTX Pulses in the Treatment of Adult Severe HSPN Completed NCT00301613 Not Applicable Mycophenolate mofetil
17 Polymorphism of the IgH Locus Regulatory Region as a Prognostic Factor During Immune Pathologies. Completed NCT01715623
18 Educational Needs of Patients With Systemic Vasculitis Completed NCT02190929
19 Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence Study Completed NCT01663129
20 Journey of Patients With Vasculitis From First Symptom to Diagnosis Completed NCT03410290
21 Impact of Vasculitis on Employment and Income Completed NCT02476292
22 Vasculitis Illness Perception (VIP) Study Completed NCT02190916
23 Reproductive Health in Men and Women With Vasculitis Completed NCT02176070
24 VCRC Tissue Repository Recruiting NCT02967068
25 Vasculitis Pregnancy Registry Recruiting NCT02593565
26 A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Recruiting NCT02374450 Not Applicable
27 Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis Active, not recruiting NCT02878018 Qi-Ji Shen-Kang formula; Zhu-Bai formula; Yu-Shen formula;angiotensin-converting enzyme (ACE) inhibitor; adrenergic receptor binder (ARB); adrenal cortical hormone; Tripterygium wilfordii polyglycosidium; immunosuppressant
28 Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura Not yet recruiting NCT03647852 Not Applicable Methylprednisolone;IVIG

Search NIH Clinical Center for Henoch-Schoenlein Purpura

Cochrane evidence based reviews: purpura, schoenlein-henoch

Genetic Tests for Henoch-Schoenlein Purpura

Anatomical Context for Henoch-Schoenlein Purpura

MalaCards organs/tissues related to Henoch-Schoenlein Purpura:

42
Skin, Kidney, Testes, Neutrophil, T Cells, Endothelial, Colon

Publications for Henoch-Schoenlein Purpura

Articles related to Henoch-Schoenlein Purpura:

(show top 50) (show all 1302)
# Title Authors Year
1
MEFV gene variants in children with Henoch-Schönlein purpura and association with clinical manifestations: a single-center Mediterranean experience. ( 30513227 )
2019
2
Successful treatment of hemorrhagic bullous Henoch-Schonlein purpura with intravenous immunoglobulins. ( 30561101 )
2019
3
Direct Immunofluorescence Results of the Skin Biopsy and Frequency of Systemic Involvement in Children with Henoch-Schonlein Purpura. ( 30600750 )
2019
4
Acute abdominal pain: Henoch-Schönlein purpura case in a young adult, a rare but important diagnosis. ( 30651252 )
2019
5
Differential expression of long non-coding RNA and mRNA in children with Henoch-Schönlein purpura nephritis. ( 30651843 )
2019
6
The change of Th17/Treg cells and IL-10/IL-17 in Chinese children with Henoch-Schonlein purpura: A PRISMA-compliant meta-analysis. ( 30653104 )
2019
7
The clinical spectrum of Henoch-Schönlein purpura in children: a single-center study. ( 30734116 )
2019
8
Tubulointerstitial Infiltration of M2 Macrophages in Henoch-Schönlein Purpura Nephritis Indicates the Presence of Glomerular Crescents and Bad Clinical Parameters. ( 30800680 )
2019
9
Different histological classifications for Henoch-Schönlein purpura nephritis: which one should be used? ( 30819179 )
2019
10
MEFV gene mutations in children with Henoch-Schönlein purpura and their correlations-do mutations matter? ( 30826945 )
2019
11
Angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to Henoch-Schönlein purpura: a meta-analysis. ( 30854921 )
2019
12
A retrospective analysis of children with Henoch-Schonlein purpura and re-evaluation of renal pathologies using Oxford classification. ( 30895528 )
2019
13
Urinalysis monitoring in children with Henoch-Schönlein purpura: Is it time to revise? ( 30896086 )
2019
14
Henoch-Schönlein purpura with acute pancreatitis: analysis of 13 cases. ( 29751784 )
2018
15
A child with arthritis, skin rash, abdominal pain and nephritis: searching beyond Henoch-Schönlein purpura-Questions. ( 30054736 )
2018
16
A child with arthritis, skin rash, abdominal pain and nephritis: searching beyond Henoch-Schönlein purpura-Answers. ( 30054737 )
2018
17
Ulcerative colitis in an adult patient mimicking Henoch-Schönlein purpura: A case report. ( 30170414 )
2018
18
Late Relapse of Henoch-Schönlein Purpura in an Adolescent Presenting as Severe Gastroduodenitis. ( 30525016 )
2018
19
Oral management of children with Henoch-Schönlein Purpura and associated Glomerulonephritis: a scoping review. ( 29790777 )
2018
20
Henoch-Schonlein purpura, post-streptococcal glomerulonephritis and acute rheumatic carditis after Group A β-haemolytic streptococcal infection. ( 28162051 )
2018
21
Colonoscopic diagnosis and reduction of recurrent intussusception owing to Henoch-Schönlein purpura without purpura. ( 29621936 )
2018
22
Risk factors for renal involvement and severe kidney disease in 2731 Chinese children with Henoch-Schönlein purpura: A retrospective study. ( 30235770 )
2018
23
Cord-derived mesenchymal stem cells therapy for liver cirrhosis in children with refractory Henoch-Schonlein purpura: A case report. ( 30461638 )
2018
24
Acute renal insufficiency and pancreatitis in a child with atypical Henoch-Schönlein purpura: efficacy of a single dose of cyclophosphamide. ( 30392430 )
2018
25
Cardiovascular, thromboembolic and renal outcomes in IgA vasculitis (Henoch-Schönlein purpura): a retrospective cohort study using routinely collected primary care data. ( 30487151 )
2018
26
Atypical purpura location in a pediatric patient with Henoch-Schönlein purpura: A case report. ( 30508916 )
2018
27
Henoch-schonlein Purpura Nephritis with Renal Interstitial Lesions. ( 30519637 )
2018
28
Henoch-Schönlein Purpura After Living Donor Liver Transplantation: Report of the First Case. ( 30522857 )
2018
29
Predisposing factors of childhood Henoch-Schönlein purpura in Anhui province, China. ( 30530785 )
2018
30
Henoch-Schonlein purpura in pregnancy: A case report. ( 30574183 )
2018
31
Leukocytoclastic vasculitis with late-onset Henoch-Schönlein purpura after trifluridine/tipiracil treatment. ( 30677817 )
2018
32
Hemorrhagic Bullous Henoch-Schönlein Purpura: Case Report and Review of the Literature. ( 30723709 )
2018
33
Food-induced IgA Vasculitis (Henoch-Schönlein Purpura). ( 30756008 )
2018
34
Renal Prognosis and Related Risk Factors for Henoch-Schönlein Purpura Nephritis: A Chinese Adult Patient Cohort. ( 29615640 )
2018
35
Henoch Schönlein Purpura Nephritis Developing in a Child with Known IgA Nephropathy. ( 29623535 )
2018
36
Incidence and risk factors for recurrent Henoch-Schönlein purpura in children from a 16-year nationwide database. ( 29661187 )
2018
37
Bullous Henoch-Schönlein purpura. Case report. ( 29664511 )
2018
38
Distinct characteristics and outcomes in elderly-onset IgA vasculitis (Henoch-Schönlein purpura) with nephritis: Nationwide cohort study of data from the Japan Renal Biopsy Registry (J-RBR). ( 29738576 )
2018
39
Hemorrhagic bullous lesions in Henoch-Schönlein purpura: a case report and review of the literature. ( 29747613 )
2018
40
Down-Regulation of miR-218-5p Promotes Apoptosis of Human Umbilical Vein Endothelial Cells Through Regulating High-Mobility Group Box-1 in Henoch-Schonlein Purpura. ( 29751935 )
2018
41
MEFV gene mutations and clinical course in pediatric patients with Henoch-Schönlein purpura. ( 29756710 )
2018
42
Can such an animal model truly represent Henoch-Schönlein purpura? ( 29761213 )
2018
43
Unusual presentation of Henöch-Schonlein purpura. ( 29848517 )
2018
44
Correlation between Traditional Chinese Medicine Symptom Patterns and the Renal Function, Immunologic Function Index, and Blood Coagulation Index in Patients with Henoch-Schönlein Purpura Nephritis. ( 29849695 )
2018
45
Reply to the letter: "Can such an animal model truly represent Henoch-Schönlein purpura?" ( 29858696 )
2018
46
Rabies post-exposure prophylaxis for a male with severe Henoch Schönlein purpura following rabies vaccination. ( 29883249 )
2018
47
Chinese herbal medicine for the treatment of Henoch-Schönlein purpura nephritis in children: A prospective cohort study protocol. ( 29901610 )
2018
48
Resolution of sinus bradycardia, high-grade heart block, and left ventricular systolic dysfunction with rituximab therapy in Henoch-Schonlein purpura. ( 29984516 )
2018
49
Severe hyperhomocysteinemia manifesting as moyamoya vasculopathy and Henoch-Schonlein purpura. ( 30021915 )
2018
50
Is Henoch-Schönlein purpura a susceptibility factor for functional gastrointestinal disorders in children? ( 30101368 )
2018

Variations for Henoch-Schoenlein Purpura

Copy number variations for Henoch-Schoenlein Purpura from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 210503 6 30400000 36600000 Copy number C4B Henoch-schoenlein purpura

Expression for Henoch-Schoenlein Purpura

Search GEO for disease gene expression data for Henoch-Schoenlein Purpura.

Pathways for Henoch-Schoenlein Purpura

GO Terms for Henoch-Schoenlein Purpura

Cellular components related to Henoch-Schoenlein Purpura according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 C3 CRP ICAM1 MPO RNASE3 VCAM1
2 azurophil granule lumen GO:0035578 8.8 C3 MPO RNASE3

Biological processes related to Henoch-Schoenlein Purpura according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.62 C3 CRP MEFV RNASE3
2 neutrophil degranulation GO:0043312 9.46 C3 HSP90AA1 MPO RNASE3
3 leukocyte cell-cell adhesion GO:0007159 9.26 ICAM1 VCAM1
4 response to lipopolysaccharide GO:0032496 9.13 ICAM1 MPO VCAM1
5 membrane to membrane docking GO:0022614 8.62 ICAM1 VCAM1

Sources for Henoch-Schoenlein Purpura

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....