MCID: HPT006
MIFTS: 29

Hepatic Angiomyolipoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Hepatic Angiomyolipoma

MalaCards integrated aliases for Hepatic Angiomyolipoma:

Name: Hepatic Angiomyolipoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:3317
NCIt 50 C27485
UMLS 71 C1333962

Summaries for Hepatic Angiomyolipoma

MalaCards based summary : Hepatic Angiomyolipoma is related to angiomyolipoma and tuberous sclerosis 1. An important gene associated with Hepatic Angiomyolipoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Human cytomegalovirus infection. Affiliated tissues include colon, and related phenotypes are integument and neoplasm

Related Diseases for Hepatic Angiomyolipoma

Diseases related to Hepatic Angiomyolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 angiomyolipoma 30.7 TSC2 TFE3 MTOR MLANA
2 tuberous sclerosis 1 30.4 TSC2 MYC MTOR
3 tuberous sclerosis 30.4 TSC2 MYC MTOR MLANA
4 liver inflammatory pseudotumor 30.1 CD34 AFP
5 hemangioma 30.0 TSC2 MYC MTOR CD34
6 hepatoblastoma 29.8 MYC MTOR AFP
7 kidney angiomyolipoma 29.6 TSC2 TFE3 MTOR MLANA
8 mesenchymal cell neoplasm 29.3 TFE3 MLANA CD34
9 hepatocellular carcinoma 10.4
10 ovarian mixed germ cell neoplasm 10.3 MTOR AFP
11 hepatoid adenocarcinoma 10.2 CEACAM3 AFP
12 rare tumor 10.2
13 adult type testicular granulosa cell tumor 10.2 MLANA AFP
14 mature teratoma of the ovary 10.2 MLANA AFP
15 ovarian cystic teratoma 10.2 MLANA AFP
16 plasmablastic lymphoma 10.2 MYC MTOR
17 ovarian solid teratoma 10.2 CD34 AFP
18 papillary adenofibroma 10.2 CD34 AFP
19 gallbladder leiomyosarcoma 10.2 CD34 AFP
20 suppressor of tumorigenicity 3 10.2 RB1 MYC
21 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.2
22 cavernous hemangioma 10.2
23 rare soft tissue tumor 10.2
24 colonic lymphangioma 10.2 CD34 AFP
25 liver leiomyoma 10.2 CD34 AFP
26 testicular fibroma 10.2 CD34 AFP
27 hemimegalencephaly 10.2 MYC MTOR
28 sclerosing hepatic carcinoma 10.2 CD34 AFP
29 peliosis hepatis 10.2 CD34 AFP
30 sarcomatous intrahepatic cholangiocarcinoma 10.2 CD34 AFP
31 kaposiform hemangioendothelioma 10.2 MTOR CD34
32 liver leiomyosarcoma 10.1 CD34 AFP
33 mediastinal cancer 10.1 CD34 AFP
34 breast angiosarcoma 10.1 MYC CD34
35 paget disease, extramammary 10.1 MLANA CEACAM3
36 cystic lymphangioma 10.1 CD34 AFP
37 hepatocellular adenoma 10.1
38 penis sarcoma 10.1 MLANA CD34
39 obstructive hydrocephalus 10.1 TSC2 AFP
40 glomangiosarcoma 10.1 MLANA CD34
41 benign perivascular tumor 10.1 MLANA CD34
42 small intestine leiomyoma 10.1 MLANA CD34
43 spindle cell lipoma 10.1 RB1 CD34
44 sarcomatoid squamous cell skin carcinoma 10.1 MLANA CD34
45 subependymal glioma 10.1 TSC2 MTOR
46 skin sarcoma 10.1 MLANA CD34
47 infiltrating angiolipoma 10.1 MLANA CD34
48 intravascular fasciitis 10.1 MLANA CD34
49 cholangiocarcinoma 10.1 MTOR CEACAM3 AFP
50 retroperitoneal sarcoma 10.1 MLANA CD34

Graphical network of the top 20 diseases related to Hepatic Angiomyolipoma:



Diseases related to Hepatic Angiomyolipoma

Symptoms & Phenotypes for Hepatic Angiomyolipoma

MGI Mouse Phenotypes related to Hepatic Angiomyolipoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.63 CD34 MLANA MYC RB1 TFE3 TSC2
2 neoplasm MP:0002006 9.35 AFP CD34 MYC RB1 TSC2
3 pigmentation MP:0001186 8.92 MLANA MYC RB1 TFE3

Drugs & Therapeutics for Hepatic Angiomyolipoma

Search Clinical Trials , NIH Clinical Center for Hepatic Angiomyolipoma

Genetic Tests for Hepatic Angiomyolipoma

Anatomical Context for Hepatic Angiomyolipoma

MalaCards organs/tissues related to Hepatic Angiomyolipoma:

40
Colon

Publications for Hepatic Angiomyolipoma

Articles related to Hepatic Angiomyolipoma:

(show top 50) (show all 236)
# Title Authors PMID Year
1
Clinical and Contrast-enhanced Ultrasound Characteristics of Epithelioid and Classic Hepatic Angiomyolipoma: Comparison With Alpha-fetoprotein-negative Hepatocellular Carcinoma. 61
33353786 2021
2
Laparoscopic hepatectomy for hepatic angiomyolipoma with preoperative diagnosis of other malignancy: a report of 2 cases. 61
33555457 2021
3
Beware the "other AML": hepatic angiomyolipoma with extensive extramedullary hematopoiesis. 61
33570613 2021
4
Hepatic angiomyolipoma with predominant epithelioid component: Diagnostic clues on aspiration and core needle biopsies. 61
33373500 2020
5
Hepatic Angiomyolipoma: Clinical Features and Imaging Findings of Quantitative Contrast-Enhanced Ultrasound Perfusion Analysis and Magnetic Resonance Imaging. 61
32383807 2020
6
[Angiomyolipoma of the liver-a case report and review of the literature]. 61
32955648 2020
7
A huge hepatic angiomyolipoma with growth during 5 years of follow-up. 61
33005323 2020
8
Contrast-enhanced sonographic appearances of two primary hepatic epithelioid angiomyolipomas. 61
32012287 2020
9
Hepatic angiomyolipoma: an international multicenter analysis on diagnosis, management and outcome. 61
31619346 2020
10
Identification of a specific ultrasonographic finding for differentiating hepatic angiomyolipoma from hepatocellular carcinoma. 61
31812881 2020
11
Benign liver angiomyolipoma: a case study. 61
32349491 2020
12
Hepatic angiomyolipoma resected by eft hepatectomy: Case report. 61
32963382 2020
13
Hepatic angiomyolipoma: A case report and literature review. 61
33212308 2020
14
Pedunculated hepatic angiomyolipoma: A rare entity. 61
31653540 2019
15
Uncommon imaging evolutions of focal liver lesions in cirrhosis. 61
31222462 2019
16
Hepatic angiomyolipoma with early drainage veins into the hepatic and portal vein. 61
30762212 2019
17
Hepatic angiomyolipoma presenting as an arterially enhancing liver lesion. 61
29392818 2019
18
Hepatic Angiomyolipoma Having FDG Uptake at the Similar Level of the Normal Liver Parenchyma. 61
31135516 2019
19
Hepatic angiomyolipoma detected using computed tomography. 61
29392859 2019
20
Giant hepatic angiomyolipoma: a case report. 61
31131134 2019
21
The differential enhancement pattern of contrast enhanced ultrasound and magnetic resonance imaging characteristics in hepatic angiomyolipoma: 7 case reports. 61
30010112 2019
22
Hepatic Epithelioid Angiomyolipoma Treated with Laparoscopic Resection: Case Report and Review of the Literature. 61
31355023 2019
23
Retinal astrocytic hamartoma in tuberous sclerosis complex in an elderly person: a case report. 61
30541513 2018
24
Selecting a suitable surgical treatment for hepatic angiomyolipoma: a retrospective analysis of 92 cases. 61
29241297 2018
25
Hepatic angiomyolipoma: mutation analysis and immunohistochemical pitfalls in diagnosis. 61
29512829 2018
26
Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages. 61
29279500 2018
27
Clinico-pathological correlation of hepatic angiomyolipoma: a series of 23 resection cases. 61
28122404 2018
28
Hepatic myomatous angiomyolipoma diagnosedpreoperatively from specific imaging features: A case report. 61
30273908 2018
29
Comparison of MRI Features of Epithelioid Hepatic Angiomyolipoma and Hepatocellular Carcinoma: Imaging Data From Two Centers. 61
30619742 2018
30
Pulmonary Lymphangiomyomatosis Associated with Renal and Hepatic Angiomyolipoma Mass in a Patient with Tuberous Sclerosis Complex. 61
29237943 2017
31
Angiomyolipoma of the Liver: A Rare Benign Tumor Treated with a Laparoscopic Approach for the First Time. 61
29102941 2017
32
Management of hepatic angiomyolipoma: A systematic review. 61
28177188 2017
33
The Histopathological Features and CT/MRI Imaging Performances in Hepatic Angiomyolipoma Patients. 61
28809731 2017
34
A case of ruptured hepatic angiomyolipoma in a young male. 61
28449573 2017
35
Primary hepatic angiomyolipoma: immunohistochemistry and electron microscopic observations: a case report. 61
28327196 2017
36
CD68-Positive Cells in Hepatic Angiomyolipoma. 61
28030864 2017
37
Hepatic Angiomyolipoma Versus Hepatocellular Carcinoma in the Noncirrhotic Liver on Gadoxetic Acid-Enhanced MRI: A Diagnostic Challenge. 61
27248975 2016
38
[Hepatic angiomyolipoma: a clinicopathologic features and prognosis analysis of 182 cases]. 61
26956960 2016
39
Comparison of CT and contrast-enhanced ultrasound findings in hepatic angiomyolipoma with pathological correlations. 61
26867906 2016
40
An Unusual Variant of Hepatic Inflammatory Angiomyolipoma: Report of a Rare Entity. 61
26927347 2016
41
Angiomyolipoma in a Patient with Situs Inversus Totalis: Managing Two Rare Diseases. 61
27525134 2016
42
Epithelioid angiomyolipoma of the liver: Clinicopathological correlation in a series of 4 cases. 61
26765232 2016
43
Hepatic angiomyolipoma: differential diagnosis from other liver tumors in a special reference to vascular imaging - importance of early drainage vein. 61
26943379 2015
44
A Case of Exophytic Angiomyolipoma of the Liver. 61
26730108 2015
45
The "peripheral washout sign" in focal hepatic lesions: not always an MRI sign of malignancy. 61
25951769 2015
46
Alterations of the mTOR pathway in hepatic angiomyolipoma with emphasis on the epithelioid variant and loss of heterogeneity of TSC1/TSC2. 61
25234729 2015
47
Computed tomographic features of lymphangioleiomyomatosis: evaluation in 138 patients. 61
25544557 2015
48
Hepatocellular carcinoma with concomitant hepatic angiomyolipoma and cavernous hemangioma in one patient. 61
25805953 2015
49
Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma: a case report. 61
25834347 2015
50
Hepatic angiomyolipoma mimicking hepatocellular carcinoma: magnetic resonance imaging and clinical pathological characteristics in 9 cases. 61
25803731 2015

Variations for Hepatic Angiomyolipoma

Expression for Hepatic Angiomyolipoma

Search GEO for disease gene expression data for Hepatic Angiomyolipoma.

Pathways for Hepatic Angiomyolipoma

Pathways related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.71 TSC2 RB1 MYC MTOR
2
Show member pathways
12.65 TSC2 RB1 MYC MTOR
3
Show member pathways
12.56 TSC2 RB1 MYC MTOR
4
Show member pathways
12.14 TSC2 MYC MTOR
5
Show member pathways
12.11 TSC2 RB1 MYC
6
Show member pathways
11.92 TSC2 RB1 MYC MTOR
7 11.77 TSC2 RB1 AFP
8 11.72 TSC2 MYC MTOR
9 11.65 TSC2 RB1 MYC MTOR
10 11.44 TFE3 RB1 MYC
11 11.44 TSC2 RB1 MYC MTOR
12 11.38 RB1 MYC MTOR
13 11.22 TSC2 MYC MTOR
14 11.16 RB1 MYC
15 11.08 TSC2 MTOR
16 11.06 TSC2 MYC MTOR
17 11.01 TSC2 MTOR
18 10.97 TSC2 RB1 MYC MTOR
19 10.96 TSC2 MTOR
20 10.84 RB1 MYC

GO Terms for Hepatic Angiomyolipoma

Biological processes related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle arrest GO:0007050 9.43 RB1 MYC MTOR
2 tissue homeostasis GO:0001894 9.32 RB1 CD34
3 regulation of osteoclast differentiation GO:0045670 9.16 TFE3 MTOR
4 energy reserve metabolic process GO:0006112 8.96 MYC MTOR
5 anoikis GO:0043276 8.62 TSC2 MTOR

Molecular functions related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphoprotein binding GO:0051219 8.62 RB1 MTOR

Sources for Hepatic Angiomyolipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....