MCID: HPT081
MIFTS: 32

Hepatic Infarction

Categories: Cardiovascular diseases, Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Hepatic Infarction

MalaCards integrated aliases for Hepatic Infarction:

Name: Hepatic Infarction 12 56 15 74
Infarct of Liver 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13738
ICD9CM 36 573.4
SNOMED-CT 69 17890003
ICD10 34 K76.3
UMLS 74 C0151731

Summaries for Hepatic Infarction

MalaCards based summary : Hepatic Infarction, also known as infarct of liver, is related to infantile liver failure syndrome 1 and catastrophic antiphospholipid syndrome. An important gene associated with Hepatic Infarction is APOH (Apolipoprotein H), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. Affiliated tissues include liver, kidney and heart, and related phenotype is homeostasis/metabolism.

Related Diseases for Hepatic Infarction

Diseases related to Hepatic Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 152)
# Related Disease Score Top Affiliating Genes
1 infantile liver failure syndrome 1 30.1 F2 GPT
2 catastrophic antiphospholipid syndrome 29.4 APOH F3 MTHFR
3 portal vein thrombosis 29.3 APOH F2 MTHFR SERPINC1
4 thrombophlebitis 29.0 APOH F2 MTHFR SERPINC1
5 antiphospholipid syndrome 28.9 APOH F2 F3 MTHFR SERPINC1
6 thrombosis 28.8 APOH F2 F3 MTHFR SERPINC1
7 eclampsia 28.7 F2 MTHFR OXT SERPINC1
8 hellp syndrome 28.6 APOH F2 F3 GPT MTHFR SERPINC1
9 liver sarcoma 10.3 ADAM17 CA4
10 papilledema 10.3 APOH F2
11 hypochondriasis 10.3 F2 PHEX
12 carotid artery occlusion 10.3 APOH CA4
13 orchitis 10.3 EDA GJB6
14 hepatoportal sclerosis 10.2 F2 GPT
15 hepatic tuberculosis 10.2 F2 GPT
16 kwashiorkor 10.2 F2 GPT
17 multiple personality disorder 10.2 CA4 OXT
18 hepatic coma 10.2 F2 GPT
19 parametritis 10.2 F2 OXT
20 mesenteric vascular occlusion 10.2 F2 MTHFR
21 ischemic neuropathy 10.2 F2 MTHFR
22 hepatitis d 10.1 F2 GPT
23 cryptogenic cirrhosis 10.1 F2 MTHFR
24 nonalcoholic steatohepatitis 10.1 F2 GPT
25 porencephaly 10.1 F2 MTHFR
26 alpha-2-plasmin inhibitor deficiency 10.1 F2 SERPINC1
27 intracranial embolism 10.1 F2 SERPINC1
28 sudden sensorineural hearing loss 10.1 APOH F2 MTHFR
29 subendocardial myocardial infarction 10.1 F2 SERPINC1
30 buerger disease 10.1 APOH F2 MTHFR
31 legg-calve-perthes disease 10.1 APOH SERPINC1
32 esophageal varix 10.0 F2 SERPINC1
33 choledocholithiasis 10.0 F2 GPT
34 anterior spinal artery syndrome 10.0 F2 SERPINC1
35 prothrombin deficiency 10.0 F2 F3
36 endocarditis 10.0 APOH F2 SERPINC1
37 vitamin b12 deficiency 10.0 ADAM17 GPT MTHFR
38 post-thrombotic syndrome 10.0 F2 SERPINC1
39 hemophilia 10.0 F2 F3
40 acute laryngitis 10.0 EDA F3
41 hypersplenism 10.0 F2 SERPINC1
42 prothrombin deficiency, congenital 10.0 APOH F2 SERPINC1
43 ischemic colitis 10.0 APOH F2 SERPINC1
44 sneddon syndrome 10.0 APOH F2 SERPINC1
45 cerebral falx meningioma 10.0 F2 F3
46 intermittent claudication 10.0 APOH F2 SERPINC1
47 qualitative platelet defect 10.0 F2 F3
48 femoral neuropathy 10.0 F2 F3
49 alcohol-related birth defect 10.0 F2 F3
50 hantavirus pulmonary syndrome 10.0 F2 F3

Comorbidity relations with Hepatic Infarction via Phenotypic Disease Network (PDN):


Heart Disease

Graphical network of the top 20 diseases related to Hepatic Infarction:



Diseases related to Hepatic Infarction

Symptoms & Phenotypes for Hepatic Infarction

MGI Mouse Phenotypes related to Hepatic Infarction:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.32 ADAM17 APOH CA4 F2 F3 GJB6

Drugs & Therapeutics for Hepatic Infarction

Search Clinical Trials , NIH Clinical Center for Hepatic Infarction

Genetic Tests for Hepatic Infarction

Anatomical Context for Hepatic Infarction

MalaCards organs/tissues related to Hepatic Infarction:

42
Liver, Kidney, Heart, Pancreatic Islet

Publications for Hepatic Infarction

Articles related to Hepatic Infarction:

(show top 50) (show all 94)
# Title Authors Year
1
"Bright Band Sign" A Grayscale Ultrasound Finding in Hepatic Infarction. ( 30666665 )
2019
2
Hepatic infarction induced by HELLP syndrome: a case report and review of the literature. ( 29848304 )
2018
3
Hepatic infarction and acute pancreatitis: a case report and review of the literature. ( 29594198 )
2018
4
Overdose of Tacrolimus as the Trigger Causing Progression of Posterior Reversible Encephalopathy Syndrome and Subsequent Hepatic Infarction After Liver Transplant: A Case Report. ( 30602365 )
2018
5
Acute mesenteric ischemia and hepatic infarction after treatment of ectopic Cushing's syndrome. ( 28480039 )
2017
6
Massive Hepatic Infarction Caused by HELLP Syndrome. ( 28670595 )
2017
7
Hepatic infarction from portal vein thrombosis: A fatal consequence of acute pancreatitis. ( 28421699 )
2017
8
Hepatic Infarction following splenectomy. ( 28109532 )
2017
9
Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome. ( 27668204 )
2016
10
Spontaneous Hepatic Infarction in a Patient with Gallbladder Cancer. ( 27462232 )
2016
11
Fulminant liver failure resulting from massive hepatic infarction associated with hemolysis, elevated liver enzymes, and low platelets syndrome. ( 27353746 )
2016
12
Hepatic Infarction Caused by Portal Vein Thrombophlebitis Misdiagnosed as Infiltrative Hepatic Malignancy with Neoplastic Thrombus. ( 27646586 )
2016
13
Recurrent gastrointestinal bleeding and hepatic infarction after liver biopsy. ( 24587666 )
2014
14
Hepatic infarction complicated with acute pancreatitis precisely diagnosed with gadoxetate disodium-enhanced magnetic resonance imaging. ( 25274233 )
2014
15
Microcirculation Approach in HELLP Syndrome Complicated by Posterior Reversible Encephalopathy Syndrome and Massive Hepatic Infarction. ( 25485160 )
2014
16
Hepatic infarction caused by vascular migration of fiducial marker previously placed under endosonographic guidance to assist radiotherapy. ( 25502251 )
2014
17
HELLP syndrome with postpartum hepatic infarction and subcapsular bleeding. ( 22515349 )
2012
18
Extensive hepatic infarction in severe preeclampsia as part of the HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): evolution of CT findings and successful treatment with plasma exchange therapy. ( 23040928 )
2012
19
MRI diagnosis and follow-up of hepatic infarction in a patient with antiphospholipid syndrome in early pregnancy. ( 20411270 )
2011
20
Failure to thrive: an unexpected finding after Whipple's resection. Image 1: Extensive hepatic infarction: an extremely rare complication of Whipple's resection. ( 21524654 )
2011
21
Lethal hepatic infarction following plasma exchange in living donor liver transplant patients. ( 21382102 )
2011
22
Liver failure after an uncovered TIPS procedure associated with hepatic infarction. ( 21160990 )
2010
23
Eleven cases of postoperative hepatic infarction following pancreato-biliary surgery. ( 19937194 )
2010
24
Acute aortic dissection causing gastroduodenal and hepatic infarction. ( 19370528 )
2009
25
Massive hepatic infarction after pure ethanol injection and radiofrequency ablation therapy for hepatocellular carcinoma: a case report. ( 19419922 )
2009
26
Late acute celiac and hepatic artery thrombosis with portal vein thrombosis resulting in hepatic infarction 12 years post orthotopic liver transplantation. ( 20009144 )
2009
27
Hepatic infarction after radiofrequency ablation of hepatocellular carcinoma with an internally cooled electrode. ( 17804775 )
2007
28
Hepatic infarction during pregnancy in catastrophic antiphospholipid syndrome. ( 17845701 )
2007
29
Veterinary diagnostic imaging. Lobar hepatic infarction with hemorrhage, secondary to a condition of chronic lymphocytic portal hepatitis with dissecting fibrosis and abundant copper accumulation. ( 17334039 )
2007
30
Retrospective study of 23 cases of hepatic infarction: CT findings and pathological correlations. ( 16623301 )
2006
31
Diabetes mellitus with hepatic infarction: a case report with literature review. ( 16937516 )
2006
32
Hepatic infarction and hepatic artery pseudoaneurysm with peritoneal bleeding after radiofrequency ablation for hepatoma. ( 16271331 )
2005
33
Multifactorial aetiology of hepatic infarction: a case report with literature review. ( 15028975 )
2004
34
Hepatic infarction following abdominal interventional procedures. ( 15255511 )
2004
35
Hepatic infarction following selective hepatic artery embolization with microcoils for iatrogenic biliary hemorrhage. ( 15341773 )
2004
36
Massive hepatic infarction in preeclampsia: successful treatment with continuous hemodiafiltration and corticosteroid therapy. ( 15493725 )
2004
37
Massive hepatic infarction complicating ultrasound-guided percutaneous radiofrequency thermal ablation. ( 15566525 )
2004
38
Prevention of hepatic infarction as acute-phase complication of TIPS by temporary balloon occlusion in a patient with primary myelofibrosis. ( 15648462 )
2004
39
Perinatal hepatic infarction in twin-twin transfusion. ( 12001202 )
2002
40
Multiple hepatic infarction after transcatheter arterial infusion with SMANCS. ( 11428589 )
2001
41
Hepatic infarction due to thrombotic angiitis; MR appearance. ( 11052886 )
2000
42
CT and MRI findings of congestive hepatic infarction caused by tumor thrombus of HCC in the hepatic vein: histopathological correlations. ( 10510907 )
1999
43
Hepatic infarction in preeclampsia as part of the HELLP syndrome: CT appearance. ( 10525815 )
1999
44
Extensive hepatic infarction caused by thrombosis of right portal vein branches and arterial vasospasm in HELLP syndrome associated with homozygous factor V Leiden. ( 9517665 )
1998
45
Hepatic infarction caused by an embolus from an atherosclerotic lesion--a case report. ( 9482518 )
1998
46
Hepatic infarction as a complication of gastric cancer surgery: report of four cases. ( 9607908 )
1998
47
Hepatic infarction secondary to arterial insufficiency in native livers: CT findings in 10 patients. ( 9646817 )
1998
48
Percutaneous hepatic infarction therapy for hepatocellular carcinoma. ( 9762991 )
1998
49
Hepatic infarction following percutaneous ethanol injection therapy for hepatocellular carcinoma. ( 9872612 )
1998
50
Hepatic infarction: unusual complication of a transjugular intrahepatic portosystemic shunt. ( 9025052 )
1997

Variations for Hepatic Infarction

Expression for Hepatic Infarction

Search GEO for disease gene expression data for Hepatic Infarction.

Pathways for Hepatic Infarction

GO Terms for Hepatic Infarction

Biological processes related to Hepatic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.58 F2 F3 SERPINC1
2 response to electrical stimulus GO:0051602 9.37 GJB6 OXT
3 blood coagulation, intrinsic pathway GO:0007597 9.32 APOH F2
4 positive regulation of blood coagulation GO:0030194 9.26 APOH F2
5 negative regulation of fibrinolysis GO:0051918 9.16 APOH F2
6 hemostasis GO:0007599 9.13 F2 F3 SERPINC1
7 regulation of blood coagulation GO:0030193 8.8 APOH F2 SERPINC1

Molecular functions related to Hepatic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.8 APOH F2 SERPINC1

Sources for Hepatic Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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