MCID: HPT081
MIFTS: 33

Hepatic Infarction

Categories: Cardiovascular diseases, Endocrine diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Hepatic Infarction

MalaCards integrated aliases for Hepatic Infarction:

Name: Hepatic Infarction 12 54 15 71
Infarct of Liver 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13738
ICD9CM 34 573.4
SNOMED-CT 67 17890003
ICD10 32 K76.3
UMLS 71 C0151731

Summaries for Hepatic Infarction

MalaCards based summary : Hepatic Infarction, also known as infarct of liver, is related to catastrophic antiphospholipid syndrome and diabetes mellitus, ketosis-prone. An important gene associated with Hepatic Infarction is APOH (Apolipoprotein H), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include liver, kidney and pancreatic islet.

Related Diseases for Hepatic Infarction

Diseases related to Hepatic Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 303)
# Related Disease Score Top Affiliating Genes
1 catastrophic antiphospholipid syndrome 30.1 F3 APOH
2 diabetes mellitus, ketosis-prone 30.0 GPT ALB
3 eclampsia 29.7 SERPINC1 F2 ALB
4 polyarteritis nodosa 29.6 GPT APOH
5 cholecystitis 29.6 GPT F2 ALB
6 cholangitis 29.6 GPT F2 ALB
7 acute liver failure 29.6 GPT F2 ALB
8 acute kidney failure 29.5 GPT F2 ALB
9 biliary atresia 29.5 GPT F2 ALB
10 hepatic encephalopathy 29.5 GPT F2 ALB
11 portal hypertension 29.5 GPT F3 F2 ALB
12 protein c deficiency 29.4 SERPINC1 F2 APOH
13 portal vein thrombosis 29.3 SERPINC1 F2 APOH AFP
14 antiphospholipid syndrome 29.3 SERPINC1 F3 F2 APOH
15 thrombosis 29.1 SERPINC1 F3 F2 APOH
16 thrombophilia due to thrombin defect 29.0 SERPINC1 F3 F2 APOH
17 hellp syndrome 29.0 SERPINC1 GPT F3 F2 APOH
18 budd-chiari syndrome 28.9 SERPINC1 F3 F2 APOH
19 mitral valve stenosis 28.9 SERPINC1 F3 F2
20 severe pre-eclampsia 28.9 SERPINC1 GPT APOH ALB
21 disseminated intravascular coagulation 28.7 SERPINC1 GPT F3 F2
22 arteriosclerosis 28.7 SERPINC1 GPT F3
23 endocarditis 28.7 SERPINC1 F2 APOH ALB
24 thrombophilia 28.6 SERPINC1 F3 F2 APOH
25 thrombocytosis 28.5 SERPINC1 F3 F2 ALB
26 liver disease 28.5 GPT F3 F2 ALB AFP
27 splenic infarction 28.4 SERPINC1 GPT F3 F2 APOH
28 pre-eclampsia 28.4 SERPINC1 F3 F2 APOH ALB AFP
29 thrombocytopenia 28.3 SERPINC1 GPT F3 F2 APOH ALB
30 hepatic coma 28.2 SERPINC1 GPT F2 ALB AFP
31 vascular disease 28.1 SERPINC1 F3 F2 APOH ALB
32 thrombophlebitis 28.1 SERPINC1 F3 F2 APOH ALB
33 liver cirrhosis 28.0 SERPINC1 GPT F3 F2 ALB AFP
34 esophageal varix 27.6 SERPINC1 GPT F3 F2 ALB AFP
35 hepatoportal sclerosis 10.4 GPT F2
36 non-a-e hepatitis 10.3 F2 ALB
37 antipyrine metabolism 10.3 F2 ALB
38 pyridoxine deficiency anemia 10.3 GPT F2
39 dipetalonemiasis 10.3 GPT ALB
40 necrotizing gastritis 10.3 F2 ALB
41 heterophyiasis 10.3 GPT ALB
42 dicrocoeliasis 10.3 GPT ALB
43 hypertensive encephalopathy 10.3 F2 ALB
44 mediastinitis 10.3 F2 ALB
45 abdominal tuberculosis 10.3 F2 ALB
46 buerger disease 10.3 F2 APOH
47 granulomatous hepatitis 10.3 GPT ALB
48 gastrointestinal tuberculosis 10.3 GPT ALB
49 heart aneurysm 10.3 GPT ALB
50 hydrops of gallbladder 10.3 GPT ALB

Comorbidity relations with Hepatic Infarction via Phenotypic Disease Network (PDN):


Heart Disease

Graphical network of the top 20 diseases related to Hepatic Infarction:



Diseases related to Hepatic Infarction

Symptoms & Phenotypes for Hepatic Infarction

Drugs & Therapeutics for Hepatic Infarction

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Bariatric Embolization Trial for the Obese Nonsurgical Not yet recruiting NCT03601273 Phase 1

Search NIH Clinical Center for Hepatic Infarction

Genetic Tests for Hepatic Infarction

Anatomical Context for Hepatic Infarction

MalaCards organs/tissues related to Hepatic Infarction:

40
Liver, Kidney, Pancreatic Islet, Heart, Colon, Myeloid

Publications for Hepatic Infarction

Articles related to Hepatic Infarction:

(show top 50) (show all 227)
# Title Authors PMID Year
1
Hepatic infarction and nodular regenerative hyperplasia of the liver with associated anticardiolipin antibodies in a young woman. 61 54
8071516 1994
2
RF Ablation Versus Cryoablation for Small Perivascular Hepatocellular Carcinoma: Propensity Score Analyses of Mid-Term Outcomes. 61
31844951 2019
3
"Bright Band Sign" A Grayscale Ultrasound Finding in Hepatic Infarction. 61
30666665 2019
4
Hepatic vasculitis mimicking multiple liver abscesses in Cogan's Syndrome. 61
31308353 2019
5
Hepatic Infarction Caused by Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus. 61
31262753 2019
6
Acute liver failure and infarction complicating TIPS placement. 61
31193126 2019
7
Placement of a Viabahn stent-graft for hepatic artery pseudoaneurysm complicated by arterial dissection caused by a guiding sheath. 61
30988861 2019
8
Percutaneous cryoablation for perivascular hepatocellular carcinoma: Therapeutic efficacy and vascular complications. 61
30043160 2019
9
A Case of Massive Hepatic Infarction in a Patient with HELLP Syndrome. 61
31041116 2019
10
Successful treatment of decompression sickness complicated with acute hepatic infarction and acute kidney injury: a case report. 61
31154689 2019
11
Overdose of Tacrolimus as the Trigger Causing Progression of Posterior Reversible Encephalopathy Syndrome and Subsequent Hepatic Infarction After Liver Transplant: A Case Report. 61
30602365 2018
12
Combined transarterial chemoembolization of the right inferior phrenic artery and radiofrequency ablation for small hepatocellular carcinoma near the diaphragm: its efficacy and safety. 61
29492603 2018
13
Minimal Risk of Biliary Tract Complications, Including Hepatic Abscess, After Transarterial Embolization for Hepatocellular Carcinoma Using Concentrated Antibiotics Mixed with Particles. 61
29797068 2018
14
Hepatic infarction induced by HELLP syndrome: a case report and review of the literature. 61
29848304 2018
15
Major pancreatic resections: normal postoperative findings and complications. 61
29450852 2018
16
Hepatic infarction and acute pancreatitis: a case report and review of the literature. 61
29594198 2018
17
Severe Postpartum Hemorrhage Complicated with Liver Infarction Resulting in Hepatic Failure Necessitating Liver Transplantation. 61
29992067 2018
18
Surgical treatment of a huge hepatic artery aneurysm without revascularization-Case Report. 61
30145501 2018
19
Hepatic Infarction following splenectomy. 61
28109532 2017
20
Rare anatomic variation of the right hepatic artery and accessory right hepatic artery supplying hepatocellular carcinoma: A case report and literature review. 61
28953651 2017
21
Hepatic infarction from portal vein thrombosis: A fatal consequence of acute pancreatitis. 61
28421699 2017
22
Impact of Radiofrequency Ablation-Induced Glisson's Capsule-Associated Complications in Patients with Hepatocellular Carcinoma. 61
28099460 2017
23
Massive Hepatic Infarction Caused by HELLP Syndrome. 61
28670595 2017
24
Acute mesenteric ischemia and hepatic infarction after treatment of ectopic Cushing's syndrome. 61
28480039 2017
25
Fulminant liver failure resulting from massive hepatic infarction associated with hemolysis, elevated liver enzymes, and low platelets syndrome. 61
27353746 2016
26
Hepatic Infarction Caused by Portal Vein Thrombophlebitis Misdiagnosed as Infiltrative Hepatic Malignancy with Neoplastic Thrombus. 61
27646586 2016
27
Hepatic infarction in a pregnant woman with antiphospholipid syndrome and triple antibody positivity: A case report focusing on catastrophic antiphospholipid syndrome. 61
27668204 2016
28
Spontaneous Hepatic Infarction in a Patient with Gallbladder Cancer. 61
27462232 2016
29
Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones. 61
26586010 2016
30
Distal pancreatectomy with celiac axis resection for pancreatic body and tail cancer invading celiac axis. 61
26446424 2015
31
Pediatric multifocal liver lesions evaluated by MRI. 61
26288526 2015
32
Radiopharmaceutical evaluation of (131)I-protohypericin as a necrosis avid compound. 61
25655506 2015
33
Flow-preserved coil embolization using a side-holed indwelling catheter for common hepatic artery pseudoaneurysm: report of three cases. 61
25015311 2015
34
Ischemic liver lesions mimicking neoplasm in a patient with severe chronic mesenteric ischemia. 61
31724564 2015
35
Evaluation of hypericin: effect of aggregation on targeting biodistribution. 61
25395358 2015
36
Pancreaticoduodenetomy combined with hepatic artery resection following preoperative hepatic arterial embolization. 61
25410529 2014
37
Transcatheter arterial embolization with N-butyl cyanoacrylate for nonvariceal upper gastrointestinal bleeding in hemodynamically unstable patients: results and predictors of clinical outcomes. 61
25282677 2014
38
Pathological findings of liver allografts evaluated at autopsy. 61
24635808 2014
39
Biodistribution and radiation dosimetry of radioiodinated hypericin as a cancer therapeutic. 61
24366374 2014
40
Recurrent gastrointestinal bleeding and hepatic infarction after liver biopsy. 61
24587666 2014
41
Hepatic infarction complicated with acute pancreatitis precisely diagnosed with gadoxetate disodium-enhanced magnetic resonance imaging. 61
25274233 2014
42
Microcirculation Approach in HELLP Syndrome Complicated by Posterior Reversible Encephalopathy Syndrome and Massive Hepatic Infarction. 61
25485160 2014
43
Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations. 61
24102315 2014
44
Hepatic infarction caused by vascular migration of fiducial marker previously placed under endosonographic guidance to assist radiotherapy. 61
25502251 2014
45
A case of diaphragmatic hernia induced by radiofrequency ablation for hepatocellular carcinoma. 61
24077629 2013
46
CT after pancreaticoduodenectomy: spectrum of normal findings and complications. 61
23789653 2013
47
[A massive hepatic infarction after radiofrequency ablation]. 61
22541446 2013
48
Radiofrequency ablation for hepatic malignancies: is needle tract cauterization necessary for preventing iatrogenic bleeding? 61
24281024 2013
49
Short-term effectiveness of radiochemoembolization for selected hepatic metastases with a combination protocol. 61
23066320 2012
50
Preoperative embolization of replaced right hepatic artery prior to pancreaticoduodenectomy. 61
22374866 2012

Variations for Hepatic Infarction

Expression for Hepatic Infarction

Search GEO for disease gene expression data for Hepatic Infarction.

Pathways for Hepatic Infarction

GO Terms for Hepatic Infarction

Cellular components related to Hepatic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.85 SERPINC1 F3 F2 APOH ALB AFP
2 extracellular exosome GO:0070062 9.8 SERPINC1 KRT3 GPT F2 APOH ALB
3 collagen-containing extracellular matrix GO:0062023 9.46 SERPINC1 F3 F2 APOH
4 blood microparticle GO:0072562 9.43 SERPINC1 F2 ALB
5 endoplasmic reticulum lumen GO:0005788 9.26 SERPINC1 F2 ALB AFP
6 extracellular space GO:0005615 9.17 SERPINC1 GPT F3 F2 APOH ALB

Biological processes related to Hepatic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.61 SERPINC1 F3 F2
2 blood coagulation, intrinsic pathway GO:0007597 9.4 F2 APOH
3 positive regulation of blood coagulation GO:0030194 9.37 F2 APOH
4 hemostasis GO:0007599 9.33 SERPINC1 F3 F2
5 negative regulation of fibrinolysis GO:0051918 9.32 F2 APOH
6 transport GO:0006810 9.26 ALB AFP
7 cellular protein metabolic process GO:0044267 9.26 SERPINC1 F2 ALB AFP
8 regulation of blood coagulation GO:0030193 8.8 SERPINC1 F2 APOH

Molecular functions related to Hepatic Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fatty acid binding GO:0005504 8.96 ALB AFP
2 heparin binding GO:0008201 8.8 SERPINC1 F2 APOH

Sources for Hepatic Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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