MCID: HPT008
MIFTS: 36

Hepatic Tuberculosis

Categories: Gastrointestinal diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Hepatic Tuberculosis

MalaCards integrated aliases for Hepatic Tuberculosis:

Name: Hepatic Tuberculosis 12 15 17
Tuberculosis, Hepatic 44 70
Tuberculosis of Liver 12
Tuberculosis Hepatic 54

Classifications:



External Ids:

Disease Ontology 12 DOID:407
MeSH 44 D014386
SNOMED-CT 67 186273003
UMLS 70 C0041313

Summaries for Hepatic Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. The infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary : Hepatic Tuberculosis, also known as tuberculosis, hepatic, is related to miliary tuberculosis and cholecystitis, and has symptoms including fever, jaundice and abdominal pain. An important gene associated with Hepatic Tuberculosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Folate Metabolism. Affiliated tissues include liver, spleen and colon, and related phenotypes are homeostasis/metabolism and liver/biliary system

Related Diseases for Hepatic Tuberculosis

Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 493)
# Related Disease Score Top Affiliating Genes
1 miliary tuberculosis 30.5 IFNG CRP CD4 ALB
2 cholecystitis 30.4 GPT F2 ALB
3 budd-chiari syndrome 30.3 F2 ALB AFP
4 obstructive jaundice 30.1 GPT GGT1 F2 CRP ALPP ALB
5 portal vein thrombosis 30.1 F2 CRP AFP
6 hepatorenal syndrome 30.1 GPT F2 ALB ACE
7 portal hypertension 30.0 GPT F2 CD4 ALB ACE
8 intestinal obstruction 29.9 GPT CRP CEACAM5 ALB
9 cholangitis 29.9 GPT GGT1 F2 CRP CEACAM5 ALPP
10 acquired immunodeficiency syndrome 29.9 IFNG CRP CD4 ALB
11 klatskin's tumor 29.8 GPT F2 CEACAM5 ALB AFP
12 cholestasis 29.8 SERPINA1 GPT GGT1 F2 ALPP ALB
13 lymph node tuberculosis 29.8 IFNG CRP CD4
14 alpha-1-antitrypsin deficiency 29.8 SERPINA1 GPT F2 ALB AFP
15 sickle cell anemia 29.8 GPT F2 CRP ALB ACE
16 liver disease 29.6 SERPINA1 GPT GGT1 F2 ALPP ALB
17 non-alcoholic fatty liver disease 29.6 SERPINA1 GPT GGT1 CRP ALB
18 abdominal tuberculosis 29.6 IFNG GPT F2 CRP CEACAM5 CD4
19 disease by infectious agent 29.5 SERPINA1 IFNG GPT CRP CD4 ALB
20 connective tissue disease 29.3 IFNG CRP CD4 ALB ACE
21 granulomatous hepatitis 29.3 GPT CRP CD4 ALB ACTA1 ACE
22 lung disease 29.3 SERPINA1 IFNG CRP CEACAM5 ALB ACE
23 exanthem 29.1 IFNG GPT F2 CRP CD4 ALB
24 deficiency anemia 29.1 GPT F2 CRP CHIT1 CD4 ALB
25 liver cirrhosis 29.0 SERPINA1 IFNG GPT GGT1 F2 CRP
26 sarcoidosis 1 29.0 IFNG CRP CHIT1 CD4 CCL18 ACE
27 hepatocellular carcinoma 28.5 SLC2A1 SERPINA1 HNF1A GPT GLUL GGT1
28 mycobacterium tuberculosis 1 10.5
29 non-a-e hepatitis 10.5 F2 ALB
30 antipyrine metabolism 10.5 F2 ALB
31 dipetalonemiasis 10.5 GPT ALB
32 heterophyiasis 10.4 GPT ALB
33 afferent loop syndrome 10.4 GPT ALB
34 primary hepatic neuroendocrine carcinoma 10.4 GPT ALPP
35 mediastinum seminoma 10.4 ALPP AFP
36 orbital osteomyelitis 10.4 F2 CRP
37 alkaline phosphatase, plasma level of, quantitative trait locus 1 10.4 GGT1 ALPP
38 achenbach syndrome 10.4 F2 CRP
39 papillary adenofibroma 10.4 F2 AFP
40 small intestine diverticulitis 10.4 F2 CRP
41 thymus sarcomatoid carcinoma 10.4 ALB AFP
42 giant hemangioma 10.4 F2 AFP
43 chronic duodenal ileus 10.4 CRP ALB
44 liver lipoma 10.4 CEACAM5 AFP
45 pancreas lymphoma 10.4 GPT ACE
46 renal pelvis squamous cell carcinoma 10.4 F2 CRP
47 pneumoconiosis due to talc 10.4 F2 ACE
48 synovial angioma 10.4 F2 CRP
49 gestational ovarian choriocarcinoma 10.4 CEACAM5 AFP
50 immature teratoma of ovary 10.4 CEACAM5 AFP

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to Hepatic Tuberculosis

Symptoms & Phenotypes for Hepatic Tuberculosis

Symptoms:

12
  • fever
  • jaundice
  • abdominal pain
  • anorexia
  • weight loss

MGI Mouse Phenotypes related to Hepatic Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.8 ACE ACTA1 AFP ALB CD4 CRP
2 liver/biliary system MP:0005370 9.23 ACE ACTA1 AFP ALB FABP1 GLUL

Drugs & Therapeutics for Hepatic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Hepatic Tuberculosis

Cochrane evidence based reviews: tuberculosis, hepatic

Genetic Tests for Hepatic Tuberculosis

Anatomical Context for Hepatic Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatic Tuberculosis:

19
Liver

MalaCards organs/tissues related to Hepatic Tuberculosis:

40
Liver, Spleen, Colon

Publications for Hepatic Tuberculosis

Articles related to Hepatic Tuberculosis:

(show top 50) (show all 268)
# Title Authors PMID Year
1
Clinical spectrum of hepatic tuberculosis: comparison between immunocompetent and immunocompromised hosts. 61 54
12930021 2003
2
Hepatic tuberculosis: comparison of miliary and local form. 54 61
7744492 1995
3
'Frosted liver' appearance in serohepatic variant of hepatic tuberculosis. 61
33727304 2021
4
Concomitant hepatic tuberculosis and hepatocellular carcinoma: a case report and review of the literature. 61
33388034 2021
5
Primary isolated hepatic tuberculosis mimicking small hepatocellular carcinoma: A case report. 61
33031307 2020
6
Hepatic tuberculosis masquerading as cholangiocarcinoma: an unusual differential for a liver mass. 61
32874539 2020
7
Incidental hepatic tuberculosis during planned resection of locally advanced ampullary carcinoma: a case report. 61
32605613 2020
8
Isolated hepatic tuberculosis presenting as hydatid cyst. 61
31758483 2020
9
Looking beyond appearances: when liver biopsy is the key for hepatic tuberculosis diagnosis. 61
32376662 2020
10
Hepatic tuberculosis mimicking metastatic colorectal cancer. 61
31732226 2020
11
The Unexpected Diagnosis of Hepatic Tuberculosis in an Immunocompetent Patient. 61
33083083 2020
12
Tubercular granuloma mimicking pyogenic liver abscess. 61
32110630 2020
13
Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget. 61
30541722 2019
14
Diagnosis and treatment of congenital tuberculosis: a systematic review of 92 cases. 61
31182120 2019
15
Primary hepatic tuberculosis masquerading as intrahepatic cholangiocarcinoma. 61
31151502 2019
16
A Clinical Diagnostic Dilemma: a Case Report of Primary Hepatic Tuberculosis. 61
30868844 2019
17
Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis. 61
30832669 2019
18
Primary hepatic tuberculosis: A rare occurrence. 61
30863814 2019
19
Primary hepaticobiliary tuberculosis mimicking gall bladder carcinoma with liver invasion: a case report. 61
31223360 2019
20
Calcified peripancreatic lymph nodes in pancreatic and hepatic tuberculosis mimicking pancreatic malignancy: A case report and review of literature. 61
30200160 2018
21
Diagnostic imaging of hepatic tuberculosis: case series. 61
29914604 2018
22
Tubercular biliary hilar stricture: A rare case report. 61
29933873 2018
23
Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better. 61
29759945 2018
24
Isolated hepatobiliary tuberculosis: a diagnostic challenge. 61
29880621 2018
25
Localized hepatic tuberculosis presenting as severe hypercalcemia. 61
29579434 2018
26
Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis. 61
29693409 2018
27
Imaging appearances of hepatic tuberculosis: experience with 12 patients. 61
29174175 2018
28
A case of hepatic tuberculosis: A tuberculoma. 61
29332659 2018
29
Isolated hepatic tuberculosis in the caudate lobe mimicking intrahepatic carcinoma. 61
28935504 2017
30
Concurrent Hepatic Tuberculosis and Hepatic Graft-versus-host Disease in an Allogeneic Hematopoietic Stem Cell Transplant Recipient: A Case Report. 61
28774674 2017
31
Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults. 61
28148232 2017
32
Primary Liver Abscess with Anterior Abdominal Wall Extension Caused by Mycobacteriumtuberculosis Complex. 61
28050433 2016
33
Primary Tubercular Liver Abscess Complicated by Tubercular Meningitis in Portal Cavernoma Cholangiopathy. 61
28119947 2016
34
Erythema induratum of Bazin and Ponçet's arthropathy as epiphenomena of hepatic tuberculosis. 61
26944370 2016
35
An Interesting Case of Non-Resolving Hepatogastric Fistula - An Unseen Cause. 61
27042532 2016
36
Isolated Hepatic Tuberculoma - A Case Report. 61
28974959 2016
37
Isolated hepatic tuberculosis masquerading as hepatic metastasis in a patient with Ewing's sarcoma of fibula. 61
27146750 2016
38
[Hepatic tuberculosis with the development of fibrosis and concomitant steatohepatitis]. 61
30289653 2016
39
Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis. 61
26984077 2016
40
The "frosted liver" appearance in hepatic tuberculosis: a rare presentation. 61
30460020 2016
41
Hepatic tuberculosis: a multimodality imaging review. 61
26499189 2015
42
A rare case of isolated macronodular hepatic tuberculosis (Tuberculous) in an immunocompetent patient. 61
26564302 2015
43
Pulmonary tuberculosis combined with hepatic tuberculosis: a case report and literature review. 61
24865423 2015
44
Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases. 61
26236700 2015
45
A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection. 61
25943103 2015
46
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. 61
25123829 2015
47
Renal transplantation in a patient with chronic granulomatous disease: case report. 61
25480525 2015
48
Primary/local hepatic tuberculosis without dissemination. 61
25628318 2015
49
Hepatic Tuberculosis Mimicking Biliary Cystadenoma: A Radiological Dilemma. 61
26504607 2015
50
Hepatic tuberculosis mimicking metastasis in a case of carcinoma sigmoid colon. 61
25949064 2015

Variations for Hepatic Tuberculosis

Expression for Hepatic Tuberculosis

Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for Hepatic Tuberculosis

Pathways related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.58 SERPINA1 ALPP ALB AFP
2
Show member pathways
11.43 SAA1 IFNG GGT1 F2 CRP ALB
3 10.9 HNF1A F2 ALB AFP

GO Terms for Hepatic Tuberculosis

Cellular components related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.9 SERPINA1 SAA1 IFNG F2 CRP CHIT1
2 extracellular exosome GO:0070062 9.73 SLC2A1 SERPINA1 SAA1 GPT GLUL GGT1
3 endoplasmic reticulum lumen GO:0005788 9.65 SERPINA1 F2 CD4 ALB AFP
4 blood microparticle GO:0072562 9.62 SLC2A1 F2 ALB ACTA1
5 extracellular space GO:0005615 9.4 SERPINA1 IFNG GPT GGT1 F2 CRP

Biological processes related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.35 SERPINA1 SAA1 F2 ALB AFP
2 acute-phase response GO:0006953 8.92 SERPINA1 SAA1 F2 CRP

Molecular functions related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.56 SLC2A1 SERPINA1 HNF1A GLUL CRP CEACAM5
2 fatty acid binding GO:0005504 8.8 FABP1 ALB AFP

Sources for Hepatic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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