MCID: HPT008
MIFTS: 37

Hepatic Tuberculosis

Categories: Infectious diseases, Liver diseases

Aliases & Classifications for Hepatic Tuberculosis

MalaCards integrated aliases for Hepatic Tuberculosis:

Name: Hepatic Tuberculosis 12 15
Tuberculosis, Hepatic 44 73
Tuberculosis of Liver 12
Tuberculosis Hepatic 55

Classifications:



External Ids:

Disease Ontology 12 DOID:407
MeSH 44 D014386
SNOMED-CT 68 186273003
UMLS 73 C0041313

Summaries for Hepatic Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. The infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary : Hepatic Tuberculosis, also known as tuberculosis, hepatic, is related to hepatitis and abdominal tuberculosis, and has symptoms including fever, anorexia and weight loss. An important gene associated with Hepatic Tuberculosis is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways are NRF2 pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include liver, liver and lung.

Related Diseases for Hepatic Tuberculosis

Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
# Related Disease Score Top Affiliating Genes
1 hepatitis 30.6 F2 GGT1 GPT
2 abdominal tuberculosis 30.1 ALB F2
3 klatskin's tumor 29.7 ALB SMUG1
4 granulomatous hepatitis 29.5 GGT1 GGT2
5 acute liver failure 29.4 ALB F2 GPT
6 portal hypertension 29.4 ALB F2 GPT
7 alpha-1-antitrypsin deficiency 29.2 ALB SERPINA1
8 obstructive jaundice 27.9 ALB ALPP F2 GGT1 GPT
9 antipyrine metabolism 10.6 ALB F2
10 non-a-e hepatitis 10.6 ALB F2
11 fournier gangrene 10.6 ALB F2
12 primary hepatic neuroendocrine carcinoma 10.6 ALPP GPT
13 splenic disease 10.6 ALB F2
14 esophageal varix 10.5 ALB F2
15 ascending cholangitis 10.5 ALB F2
16 hepatoportal sclerosis 10.5 F2 GPT
17 hypersplenism 10.5 ALB F2
18 compartment syndrome 10.5 ALB F2
19 alkaline phosphatase, plasma level of, quantitative trait locus 1 10.5 ALPP GGT1
20 nonalcoholic steatohepatitis 10.5 F2 GPT
21 hepatitis d 10.5 F2 GPT
22 hepatorenal syndrome 10.5 ALB F2
23 hepatic vascular disease 10.5 ALB F2
24 dysfibrinogenemia 10.5 ALB F2
25 vein disease 10.5 ALB F2
26 intermittent claudication 10.4 ALB F2
27 nutritional deficiency disease 10.4 ALB F2
28 typhoid fever 10.4 ALB F2
29 dengue hemorrhagic fever 10.4 ALB F2
30 homocysteinemia 10.4 ALB F2
31 protein-energy malnutrition 10.4 ALB GPT
32 alcoholic liver cirrhosis 10.3 ALB F2
33 endocarditis 10.3 ALB F2
34 eccrine adenocarcinoma 10.3 F2 SMUG1
35 autoimmune disease of urogenital tract 10.3 ALB GGT2
36 endometrial small cell carcinoma 10.3 F2 SMUG1
37 femoral neuropathy 10.3 F2 SMUG1
38 extrahepatic cholestasis 10.3 GGT1 GPT
39 cyclosporiasis 10.3 GGT1 GGT2
40 testis seminoma 10.3 ALPP SMUG1
41 cholelithiasis 10.3 ALB GPT
42 gastrointestinal tuberculosis 10.3 ALB SMUG1
43 algoneurodystrophy 10.3 GGT1 GGT2
44 pulmonary embolism 10.3 ALB F2
45 periampullary adenoma 10.3 GGT1 GGT2
46 ethmoid sinus cancer 10.3 GGT1 GGT2
47 ethmoid sinus adenocarcinoma 10.3 GGT1 GGT2
48 non-secretory myeloma 10.3 ALB SMUG1
49 peliosis hepatis 10.2 F2 SMUG1
50 endocardium disease 10.2 F2 SMUG1

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to Hepatic Tuberculosis

Symptoms & Phenotypes for Hepatic Tuberculosis

Symptoms:

12
  • fever
  • anorexia
  • weight loss
  • abdominal pain
  • jaundice

Drugs & Therapeutics for Hepatic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Hepatic Tuberculosis

Cochrane evidence based reviews: tuberculosis, hepatic

Genetic Tests for Hepatic Tuberculosis

Anatomical Context for Hepatic Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatic Tuberculosis:

19
Liver

MalaCards organs/tissues related to Hepatic Tuberculosis:

41
Liver, Lung, Colon

Publications for Hepatic Tuberculosis

Articles related to Hepatic Tuberculosis:

(show top 50) (show all 91)
# Title Authors Year
1
Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better. ( 29759945 )
2018
2
Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis. ( 29693409 )
2018
3
A case of hepatic tuberculosis: A tuberculoma. ( 29332659 )
2018
4
Localized hepatic tuberculosis presenting as severe hypercalcemia. ( 29579434 )
2018
5
Diagnostic imaging of hepatic tuberculosis: case series. ( 29914604 )
2018
6
Imaging appearances of hepatic tuberculosis: experience with 12 patients. ( 29174175 )
2018
7
Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults. ( 28148232 )
2017
8
Concurrent Hepatic Tuberculosis and Hepatic Graft-versus-host Disease in an Allogeneic Hematopoietic Stem Cell Transplant Recipient: A Case Report. ( 28774674 )
2017
9
Isolated hepatic tuberculosis in the caudate lobe mimicking intrahepatic carcinoma. ( 28935504 )
2017
10
Isolated hepatic tuberculosis masquerading as hepatic metastasis in a patient with Ewing's sarcoma of fibula. ( 27146750 )
2016
11
Erythema induratum of Bazin and PonAset's arthropathy as epiphenomena of hepatic tuberculosis. ( 26944370 )
2016
12
Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis. ( 26984077 )
2016
13
Hepatic tuberculosis: a multimodality imaging review. ( 26499189 )
2015
14
Hepatic Tuberculosis Mimicking Biliary Cystadenoma: A Radiological Dilemma. ( 26504607 )
2015
15
Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases. ( 26236700 )
2015
16
Hepatic tuberculosis mimicking metastasis in a case of carcinoma sigmoid colon. ( 25949064 )
2015
17
Primary/local hepatic tuberculosis without dissemination. ( 25628318 )
2015
18
A rare case of isolated macronodular hepatic tuberculosis (Tuberculous) in an immunocompetent patient. ( 26564302 )
2015
19
A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection. ( 25943103 )
2015
20
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. ( 25123829 )
2014
21
Isolated hepatic tuberculosis: An uncommon presentation of a common culprit. ( 25031646 )
2014
22
Co-existence of hepatocellular carcinoma and hepatic tuberculosis. ( 24476016 )
2014
23
A case of multiple macronodular hepatic tuberculosis difficult to differentiate from hepatocellular carcinoma with intrahepatic metastasis: CT-guided fine needle aspiration biopsy confirmed the diagnosis. ( 25550879 )
2014
24
Multiple hepatic lesions in a case of isolated hepatic tuberculosis simulating metastases on 18F-FDG PET/CT imaging. ( 25088112 )
2014
25
Isolated hepatic tuberculosis: a rare cause of hepatic mass lesions. ( 24918144 )
2014
26
Pulmonary tuberculosis combined with hepatic tuberculosis: a case report and literature review. ( 24865423 )
2014
27
Primary hepatic tuberculosis presenting as acute liver failure. ( 25988063 )
2014
28
Primary hepatic tuberculosis in immunocompetent adults: a UK case series. ( 25988061 )
2014
29
Hepatic Tuberculosis Mimics Metastasis Revealed by 18F-FDG PET/CT. ( 24152632 )
2013
30
Primary isolated hepatic tuberculosis. ( 23673179 )
2013
31
Probable hepatic tuberculosis masquerading as Klatskin tumour in an immunocompetent patient. ( 24343799 )
2013
32
Hepatic tuberculosis: a rare cause of fluorodeoxyglucose hepatic superscan with background suppression on positron emission tomography. ( 24347039 )
2013
33
The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis. ( 23967026 )
2013
34
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of literature. ( 24179582 )
2013
35
Primary hepatic tuberculosis: a rare but fatal clinical entity if undiagnosed. ( 22575985 )
2012
36
Hepatic tuberculosis presenting with extreme hyperferritinemia masquerading as adult-onset Still's disease: a case report. ( 22788693 )
2012
37
Pseudo-tumoral hepatic tuberculosis discovered after surgical resection. ( 24765426 )
2012
38
Hepatic tuberculosis in a patient treated with infliximab. ( 21793022 )
2011
39
Pseudotumoral hepatic tuberculosis with pericardial abscess. ( 21045410 )
2010
40
Corticosteroids in the treatment of hepatic tuberculosis: case report and review of the literature. ( 20092380 )
2010
41
Pseudo-tumoral hepatic tuberculosis: a report of two cases. ( 20306917 )
2010
42
The nodular form of hepatic tuberculosis: contrast-enhanced ultrasonographic findings with pathologic correlation. ( 20498462 )
2010
43
Radiological findings of isolated hepatic tuberculosis in a child with tubulointerstitial nephritis-uveitis syndrome. ( 19137283 )
2009
44
Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host. ( 20140362 )
2009
45
Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic. ( 19795040 )
2009
46
CT appearance of primary localized nodular hepatic tuberculosis in an immunocompetent patient. ( 18541946 )
2008
47
Isolated hepatic tuberculosis presenting as cystic-like and tumour-like mass lesions. ( 21490832 )
2008
48
Hepatic tuberculosis mimicking Klatskin tumor: a diagnostic dilemma. ( 18723964 )
2008
49
Isolated hepatic tuberculosis. ( 20071827 )
2008
50
Granulomatous hepatitis: tuberculosis or not? ( 18241177 )
2008

Variations for Hepatic Tuberculosis

Expression for Hepatic Tuberculosis

Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for Hepatic Tuberculosis

GO Terms for Hepatic Tuberculosis

Cellular components related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 ALB F2 GGT1 GPT SERPINA1
2 platelet alpha granule lumen GO:0031093 9.26 ALB SERPINA1
3 endoplasmic reticulum lumen GO:0005788 9.13 ALB F2 SERPINA1
4 extracellular exosome GO:0070062 9.1 ALB F2 GGT1 GGT2 GPT SERPINA1

Biological processes related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.43 ALB F2 SERPINA1
2 hemostasis GO:0007599 9.37 F2 SERPINA1
3 acute-phase response GO:0006953 9.32 F2 SERPINA1
4 zymogen activation GO:0031638 9.16 GGT1 GGT2
5 glutathione catabolic process GO:0006751 8.96 GGT1 GGT2
6 leukotriene D4 biosynthetic process GO:1901750 8.62 GGT1 GGT2

Molecular functions related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 8.96 ALB GPT
2 glutathione hydrolase activity GO:0036374 8.62 GGT1 GGT2

Sources for Hepatic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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