MCID: HPT008
MIFTS: 42

Hepatic Tuberculosis

Categories: Endocrine diseases, Gastrointestinal diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Hepatic Tuberculosis

MalaCards integrated aliases for Hepatic Tuberculosis:

Name: Hepatic Tuberculosis 12 15
Tuberculosis, Hepatic 44 73
Tuberculosis of Liver 12
Tuberculosis Hepatic 55

Classifications:



External Ids:

Disease Ontology 12 DOID:407
MeSH 44 D014386
UMLS 73 C0041313

Summaries for Hepatic Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. The infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary : Hepatic Tuberculosis, also known as tuberculosis, hepatic, is related to hepatitis and abdominal tuberculosis, and has symptoms including fever, abdominal pain and weight loss. An important gene associated with Hepatic Tuberculosis is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways are NRF2 pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include liver, testes and colon.

Related Diseases for Hepatic Tuberculosis

Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
# Related Disease Score Top Affiliating Genes
1 hepatitis 29.8 F2 GGT1 GPT
2 abdominal tuberculosis 29.7 ALB F2
3 klatskin's tumor 29.6 ALB SMUG1
4 infantile liver failure syndrome 1 29.5 ALB F2 GPT
5 acute liver failure 29.5 ALB F2 GPT
6 portal hypertension 29.5 ALB F2 GPT
7 hepatitis b 29.4 ALB F2 GGT1 GPT
8 alpha-1-antitrypsin deficiency 29.4 ALB SERPINA1
9 obstructive jaundice 29.0 ALB ALPP F2 GGT1 GPT
10 antipyrine metabolism 10.2 ALB F2
11 non-a-e hepatitis 10.2 ALB F2
12 epstein-barr virus hepatitis 10.2 ALB F2
13 fournier gangrene 10.2 ALB F2
14 primary hepatic neuroendocrine carcinoma 10.2 ALPP GPT
15 splenic disease 10.2 ALB F2
16 esophageal varix 10.2 ALB F2
17 ascending cholangitis 10.2 ALB F2
18 hepatoportal sclerosis 10.2 F2 GPT
19 peritonitis 10.2 ALB F2
20 hypersplenism 10.2 ALB F2
21 alkaline phosphatase, plasma level of, quantitative trait locus 1 10.2 ALPP GGT1
22 hepatitis d 10.2 F2 GPT
23 compartment syndrome 10.2 ALB F2
24 nonalcoholic steatohepatitis 10.2 F2 GPT
25 hepatorenal syndrome 10.1 ALB F2
26 hepatic vascular disease 10.1 ALB F2
27 pulmonary artery disease 10.1 ALB F2
28 dysfibrinogenemia 10.1 ALB F2
29 vein disease 10.1 ALB F2
30 intermittent claudication 10.1 ALB F2
31 typhoid fever 10.1 ALB F2
32 dengue hemorrhagic fever 10.1 ALB F2
33 protein-energy malnutrition 10.1 ALB GPT
34 eccrine adenocarcinoma 10.1 F2 SMUG1
35 extrahepatic cholestasis 10.1 GGT1 GPT
36 homocysteinemia 10.1 ALB F2
37 cyclosporiasis 10.1 GGT1 GGT2
38 gastrointestinal tuberculosis 10.1 ALB SMUG1
39 algoneurodystrophy 10.1 GGT1 GGT2
40 periampullary adenoma 10.1 GGT1 GGT2
41 pancreatic cystadenocarcinoma 10.1 GGT1 GGT2
42 non-secretory myeloma 10.1 ALB SMUG1
43 testis seminoma 10.1 ALPP SMUG1
44 ethmoid sinus cancer 10.1 GGT1 GGT2
45 ethmoid sinus adenocarcinoma 10.1 GGT1 GGT2
46 alcoholic liver cirrhosis 10.1 ALB F2
47 endocardium disease 10.1 F2 SMUG1
48 tuberculous peritonitis 10.1 ALB SMUG1
49 colloid carcinoma of the pancreas 10.1 GGT1 GGT2
50 peliosis hepatis 10.1 F2 SMUG1

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to Hepatic Tuberculosis

Symptoms & Phenotypes for Hepatic Tuberculosis

Symptoms:

12
  • fever
  • abdominal pain
  • weight loss
  • jaundice
  • anorexia

Drugs & Therapeutics for Hepatic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Hepatic Tuberculosis

Cochrane evidence based reviews: tuberculosis, hepatic

Genetic Tests for Hepatic Tuberculosis

Anatomical Context for Hepatic Tuberculosis

MalaCards organs/tissues related to Hepatic Tuberculosis:

41
Liver, Testes, Colon, Lymph Node, Skin, Pancreas, Testis

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatic Tuberculosis:

19
Liver

Publications for Hepatic Tuberculosis

Articles related to Hepatic Tuberculosis:

(show top 50) (show all 95)
# Title Authors Year
1
Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better. ( 29759945 )
2018
2
Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis. ( 29693409 )
2018
3
A case of hepatic tuberculosis: A tuberculoma. ( 29332659 )
2018
4
Localized hepatic tuberculosis presenting as severe hypercalcemia. ( 29579434 )
2018
5
Diagnostic imaging of hepatic tuberculosis: case series. ( 29914604 )
2018
6
Imaging appearances of hepatic tuberculosis: experience with 12 patients. ( 29174175 )
2018
7
Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget. ( 30541722 )
2018
8
Calcified peripancreatic lymph nodes in pancreatic and hepatic tuberculosis mimicking pancreatic malignancy: A case report and review of literature. ( 30200160 )
2018
9
Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults. ( 28148232 )
2017
10
Concurrent Hepatic Tuberculosis and Hepatic Graft-versus-host Disease in an Allogeneic Hematopoietic Stem Cell Transplant Recipient: A Case Report. ( 28774674 )
2017
11
Isolated hepatic tuberculosis in the caudate lobe mimicking intrahepatic carcinoma. ( 28935504 )
2017
12
Isolated hepatic tuberculosis masquerading as hepatic metastasis in a patient with Ewing's sarcoma of fibula. ( 27146750 )
2016
13
Erythema induratum of Bazin and PonAset's arthropathy as epiphenomena of hepatic tuberculosis. ( 26944370 )
2016
14
Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis. ( 26984077 )
2016
15
The "frosted liver" appearance in hepatic tuberculosis: a rare presentation. ( 30460020 )
2016
16
Hepatic tuberculosis: a multimodality imaging review. ( 26499189 )
2015
17
Hepatic Tuberculosis Mimicking Biliary Cystadenoma: A Radiological Dilemma. ( 26504607 )
2015
18
Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases. ( 26236700 )
2015
19
Hepatic tuberculosis mimicking metastasis in a case of carcinoma sigmoid colon. ( 25949064 )
2015
20
Primary/local hepatic tuberculosis without dissemination. ( 25628318 )
2015
21
A rare case of isolated macronodular hepatic tuberculosis (Tuberculous) in an immunocompetent patient. ( 26564302 )
2015
22
A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection. ( 25943103 )
2015
23
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. ( 25123829 )
2014
24
Isolated hepatic tuberculosis: An uncommon presentation of a common culprit. ( 25031646 )
2014
25
Co-existence of hepatocellular carcinoma and hepatic tuberculosis. ( 24476016 )
2014
26
A case of multiple macronodular hepatic tuberculosis difficult to differentiate from hepatocellular carcinoma with intrahepatic metastasis: CT-guided fine needle aspiration biopsy confirmed the diagnosis. ( 25550879 )
2014
27
Multiple hepatic lesions in a case of isolated hepatic tuberculosis simulating metastases on 18F-FDG PET/CT imaging. ( 25088112 )
2014
28
Isolated hepatic tuberculosis: a rare cause of hepatic mass lesions. ( 24918144 )
2014
29
Pulmonary tuberculosis combined with hepatic tuberculosis: a case report and literature review. ( 24865423 )
2014
30
Primary hepatic tuberculosis presenting as acute liver failure. ( 25988063 )
2014
31
Primary hepatic tuberculosis in immunocompetent adults: a UK case series. ( 25988061 )
2014
32
Hepatic Tuberculosis Mimics Metastasis Revealed by 18F-FDG PET/CT. ( 24152632 )
2013
33
Primary isolated hepatic tuberculosis. ( 23673179 )
2013
34
Probable hepatic tuberculosis masquerading as Klatskin tumour in an immunocompetent patient. ( 24343799 )
2013
35
Hepatic tuberculosis: a rare cause of fluorodeoxyglucose hepatic superscan with background suppression on positron emission tomography. ( 24347039 )
2013
36
The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis. ( 23967026 )
2013
37
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of literature. ( 24179582 )
2013
38
Primary hepatic tuberculosis: a rare but fatal clinical entity if undiagnosed. ( 22575985 )
2012
39
Hepatic tuberculosis presenting with extreme hyperferritinemia masquerading as adult-onset Still's disease: a case report. ( 22788693 )
2012
40
Pseudo-tumoral hepatic tuberculosis discovered after surgical resection. ( 24765426 )
2012
41
Hepatic tuberculosis in a patient treated with infliximab. ( 21793022 )
2011
42
Pseudotumoral hepatic tuberculosis with pericardial abscess. ( 21045410 )
2010
43
Corticosteroids in the treatment of hepatic tuberculosis: case report and review of the literature. ( 20092380 )
2010
44
Pseudo-tumoral hepatic tuberculosis: a report of two cases. ( 20306917 )
2010
45
The nodular form of hepatic tuberculosis: contrast-enhanced ultrasonographic findings with pathologic correlation. ( 20498462 )
2010
46
Radiological findings of isolated hepatic tuberculosis in a child with tubulointerstitial nephritis-uveitis syndrome. ( 19137283 )
2009
47
Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host. ( 20140362 )
2009
48
Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic. ( 19795040 )
2009
49
CT appearance of primary localized nodular hepatic tuberculosis in an immunocompetent patient. ( 18541946 )
2008
50
Isolated hepatic tuberculosis presenting as cystic-like and tumour-like mass lesions. ( 21490832 )
2008

Variations for Hepatic Tuberculosis

Expression for Hepatic Tuberculosis

Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for Hepatic Tuberculosis

GO Terms for Hepatic Tuberculosis

Cellular components related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 ALB F2 GGT1 GPT SERPINA1
2 platelet alpha granule lumen GO:0031093 9.26 ALB SERPINA1
3 endoplasmic reticulum lumen GO:0005788 9.13 ALB F2 SERPINA1
4 extracellular exosome GO:0070062 9.1 ALB F2 GGT1 GGT2 GPT SERPINA1

Biological processes related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.61 ALB F2 SERPINA1
2 regulation of inflammatory response GO:0050727 9.54 GGT1 GGT2
3 hemostasis GO:0007599 9.52 F2 SERPINA1
4 cellular amino acid metabolic process GO:0006520 9.51 GGT1 GGT2
5 glutathione metabolic process GO:0006749 9.49 GGT1 GGT2
6 acute-phase response GO:0006953 9.48 F2 SERPINA1
7 response to tumor necrosis factor GO:0034612 9.46 GGT1 GGT2
8 glutamate metabolic process GO:0006536 9.4 GGT1 GGT2
9 zymogen activation GO:0031638 9.37 GGT1 GGT2
10 glutathione catabolic process GO:0006751 9.32 GGT1 GGT2
11 leukotriene D4 biosynthetic process GO:1901750 9.26 GGT1 GGT2
12 cysteine biosynthetic process GO:0019344 9.16 GGT1 GGT2
13 regulation of immune system process GO:0002682 8.96 GGT1 GGT2
14 peptide modification GO:0031179 8.62 GGT1 GGT2

Molecular functions related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 9.16 ALB GPT
2 glutathione hydrolase activity GO:0036374 8.96 GGT1 GGT2
3 peptidyltransferase activity GO:0000048 8.62 GGT1 GGT2

Sources for Hepatic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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