MCID: HPT008
MIFTS: 38

Hepatic Tuberculosis

Categories: Endocrine diseases, Gastrointestinal diseases, Infectious diseases, Liver diseases

Aliases & Classifications for Hepatic Tuberculosis

MalaCards integrated aliases for Hepatic Tuberculosis:

Name: Hepatic Tuberculosis 12 15 17
Tuberculosis, Hepatic 45 74
Tuberculosis of Liver 12
Tuberculosis Hepatic 56

Classifications:



External Ids:

Disease Ontology 12 DOID:407
MeSH 45 D014386
UMLS 74 C0041313

Summaries for Hepatic Tuberculosis

Disease Ontology : 12 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. The infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary : Hepatic Tuberculosis, also known as tuberculosis, hepatic, is related to abdominal tuberculosis and hepatitis, and has symptoms including fever, abdominal pain and weight loss. An important gene associated with Hepatic Tuberculosis is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways are NRF2 pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include liver, liver and colon.

Related Diseases for Hepatic Tuberculosis

Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 137)
# Related Disease Score Top Affiliating Genes
1 abdominal tuberculosis 29.9 ALB F2
2 hepatitis 29.8 F2 GGT1 GPT
3 klatskin's tumor 29.7 ALB SMUG1
4 hepatitis b 29.6 ALB F2 GGT1 GPT
5 infantile liver failure syndrome 1 29.6 ALB F2 GPT
6 acute liver failure 29.6 ALB F2 GPT
7 portal hypertension 29.6 ALB F2 GPT
8 alpha-1-antitrypsin deficiency 29.5 ALB SERPINA1
9 obstructive jaundice 28.9 ALB ALPP F2 GGT1 GPT
10 primary hepatic neuroendocrine carcinoma 10.3 ALPP GPT
11 hepatoportal sclerosis 10.3 F2 GPT
12 antipyrine metabolism 10.3 ALB F2
13 non-a-e hepatitis 10.3 ALB F2
14 epstein-barr virus hepatitis 10.3 ALB F2
15 hepatitis d 10.3 F2 GPT
16 nonalcoholic steatohepatitis 10.3 F2 GPT
17 fournier gangrene 10.3 ALB F2
18 alkaline phosphatase, plasma level of, quantitative trait locus 1 10.3 ALPP GGT1
19 splenic disease 10.3 ALB F2
20 esophageal varix 10.3 ALB F2
21 ascending cholangitis 10.3 ALB F2
22 hypersplenism 10.2 ALB F2
23 compartment syndrome 10.2 ALB F2
24 hepatorenal syndrome 10.2 ALB F2
25 hepatic vascular disease 10.2 ALB F2
26 pulmonary artery disease 10.2 ALB F2
27 dysfibrinogenemia 10.2 ALB F2
28 extrahepatic cholestasis 10.2 GGT1 GPT
29 eccrine adenocarcinoma 10.2 F2 SMUG1
30 vein disease 10.2 ALB F2
31 gastrointestinal tuberculosis 10.2 ALB SMUG1
32 protein-energy malnutrition 10.2 ALB GPT
33 testis seminoma 10.2 ALPP SMUG1
34 intermittent claudication 10.2 ALB F2
35 endocardium disease 10.2 F2 SMUG1
36 non-secretory myeloma 10.2 ALB SMUG1
37 cyclosporiasis 10.2 GGT1 GGT2
38 peliosis hepatis 10.2 F2 SMUG1
39 algoneurodystrophy 10.2 GGT1 GGT2
40 periampullary adenoma 10.2 GGT1 GGT2
41 tuberculous peritonitis 10.2 ALB SMUG1
42 pancreatic cystadenocarcinoma 10.2 GGT1 GGT2
43 subendocardial myocardial infarction 10.2 F2 SERPINA1
44 typhoid fever 10.2 ALB F2
45 ethmoid sinus cancer 10.1 GGT1 GGT2
46 ethmoid sinus adenocarcinoma 10.1 GGT1 GGT2
47 pericardium disease 10.1 ALB SMUG1
48 colloid carcinoma of the pancreas 10.1 GGT1 GGT2
49 dengue hemorrhagic fever 10.1 ALB F2
50 gastritis, familial giant hypertrophic 10.1 ALB SERPINA1

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to Hepatic Tuberculosis

Symptoms & Phenotypes for Hepatic Tuberculosis

Symptoms:

12
  • fever
  • abdominal pain
  • weight loss
  • jaundice
  • anorexia

Drugs & Therapeutics for Hepatic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Hepatic Tuberculosis

Cochrane evidence based reviews: tuberculosis, hepatic

Genetic Tests for Hepatic Tuberculosis

Anatomical Context for Hepatic Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatic Tuberculosis:

20
Liver

MalaCards organs/tissues related to Hepatic Tuberculosis:

42
Liver, Colon, Lymph Node

Publications for Hepatic Tuberculosis

Articles related to Hepatic Tuberculosis:

(show top 50) (show all 97)
# Title Authors Year
1
Primary hepatic tuberculosis: A rare occurrence. ( 30863814 )
2019
2
A Clinical Diagnostic Dilemma: a Case Report of Primary Hepatic Tuberculosis. ( 30868844 )
2019
3
Diagnosis of local hepatic tuberculosis through next-generation sequencing: Smarter, faster and better. ( 29759945 )
2018
4
Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis. ( 29693409 )
2018
5
A case of hepatic tuberculosis: A tuberculoma. ( 29332659 )
2018
6
Localized hepatic tuberculosis presenting as severe hypercalcemia. ( 29579434 )
2018
7
Diagnostic imaging of hepatic tuberculosis: case series. ( 29914604 )
2018
8
Imaging appearances of hepatic tuberculosis: experience with 12 patients. ( 29174175 )
2018
9
Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget. ( 30541722 )
2018
10
Calcified peripancreatic lymph nodes in pancreatic and hepatic tuberculosis mimicking pancreatic malignancy: A case report and review of literature. ( 30200160 )
2018
11
Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults. ( 28148232 )
2017
12
Concurrent Hepatic Tuberculosis and Hepatic Graft-versus-host Disease in an Allogeneic Hematopoietic Stem Cell Transplant Recipient: A Case Report. ( 28774674 )
2017
13
Isolated hepatic tuberculosis in the caudate lobe mimicking intrahepatic carcinoma. ( 28935504 )
2017
14
Isolated hepatic tuberculosis masquerading as hepatic metastasis in a patient with Ewing's sarcoma of fibula. ( 27146750 )
2016
15
Erythema induratum of Bazin and PonAset's arthropathy as epiphenomena of hepatic tuberculosis. ( 26944370 )
2016
16
Localized Hepatic Tuberculosis with Imaging Changes Caused by the Progression of Tuberculosis. ( 26984077 )
2016
17
The "frosted liver" appearance in hepatic tuberculosis: a rare presentation. ( 30460020 )
2016
18
Hepatic tuberculosis: a multimodality imaging review. ( 26499189 )
2015
19
Hepatic Tuberculosis Mimicking Biliary Cystadenoma: A Radiological Dilemma. ( 26504607 )
2015
20
Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases. ( 26236700 )
2015
21
Hepatic tuberculosis mimicking metastasis in a case of carcinoma sigmoid colon. ( 25949064 )
2015
22
Primary/local hepatic tuberculosis without dissemination. ( 25628318 )
2015
23
A rare case of isolated macronodular hepatic tuberculosis (Tuberculous) in an immunocompetent patient. ( 26564302 )
2015
24
A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection. ( 25943103 )
2015
25
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. ( 25123829 )
2014
26
Isolated hepatic tuberculosis: An uncommon presentation of a common culprit. ( 25031646 )
2014
27
Co-existence of hepatocellular carcinoma and hepatic tuberculosis. ( 24476016 )
2014
28
A case of multiple macronodular hepatic tuberculosis difficult to differentiate from hepatocellular carcinoma with intrahepatic metastasis: CT-guided fine needle aspiration biopsy confirmed the diagnosis. ( 25550879 )
2014
29
Multiple hepatic lesions in a case of isolated hepatic tuberculosis simulating metastases on 18F-FDG PET/CT imaging. ( 25088112 )
2014
30
Isolated hepatic tuberculosis: a rare cause of hepatic mass lesions. ( 24918144 )
2014
31
Pulmonary tuberculosis combined with hepatic tuberculosis: a case report and literature review. ( 24865423 )
2014
32
Primary hepatic tuberculosis presenting as acute liver failure. ( 25988063 )
2014
33
Primary hepatic tuberculosis in immunocompetent adults: a UK case series. ( 25988061 )
2014
34
Hepatic Tuberculosis Mimics Metastasis Revealed by 18F-FDG PET/CT. ( 24152632 )
2013
35
Primary isolated hepatic tuberculosis. ( 23673179 )
2013
36
Probable hepatic tuberculosis masquerading as Klatskin tumour in an immunocompetent patient. ( 24343799 )
2013
37
Hepatic tuberculosis: a rare cause of fluorodeoxyglucose hepatic superscan with background suppression on positron emission tomography. ( 24347039 )
2013
38
The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis. ( 23967026 )
2013
39
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of literature. ( 24179582 )
2013
40
Primary hepatic tuberculosis: a rare but fatal clinical entity if undiagnosed. ( 22575985 )
2012
41
Hepatic tuberculosis presenting with extreme hyperferritinemia masquerading as adult-onset Still's disease: a case report. ( 22788693 )
2012
42
Pseudo-tumoral hepatic tuberculosis discovered after surgical resection. ( 24765426 )
2012
43
Hepatic tuberculosis in a patient treated with infliximab. ( 21793022 )
2011
44
Pseudotumoral hepatic tuberculosis with pericardial abscess. ( 21045410 )
2010
45
Corticosteroids in the treatment of hepatic tuberculosis: case report and review of the literature. ( 20092380 )
2010
46
Pseudo-tumoral hepatic tuberculosis: a report of two cases. ( 20306917 )
2010
47
The nodular form of hepatic tuberculosis: contrast-enhanced ultrasonographic findings with pathologic correlation. ( 20498462 )
2010
48
Radiological findings of isolated hepatic tuberculosis in a child with tubulointerstitial nephritis-uveitis syndrome. ( 19137283 )
2009
49
Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host. ( 20140362 )
2009
50
Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic. ( 19795040 )
2009

Variations for Hepatic Tuberculosis

Expression for Hepatic Tuberculosis

Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for Hepatic Tuberculosis

GO Terms for Hepatic Tuberculosis

Cellular components related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 ALB F2 GGT1 GPT SERPINA1
2 extracellular exosome GO:0070062 9.17 ALB F2 GGT1 GGT2 GGTLC3 GPT
3 endoplasmic reticulum lumen GO:0005788 9.13 ALB F2 SERPINA1

Biological processes related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.78 F2 GGT1 GGT2 GGTLC3
2 cellular protein metabolic process GO:0044267 9.61 ALB F2 SERPINA1
3 hemostasis GO:0007599 9.54 F2 SERPINA1
4 cellular amino acid metabolic process GO:0006520 9.52 GGT1 GGT2
5 glutathione metabolic process GO:0006749 9.51 GGT1 GGT2
6 acute-phase response GO:0006953 9.49 F2 SERPINA1
7 response to tumor necrosis factor GO:0034612 9.46 GGT1 GGT2
8 glutamate metabolic process GO:0006536 9.4 GGT1 GGT2
9 zymogen activation GO:0031638 9.37 GGT1 GGT2
10 cysteine biosynthetic process GO:0019344 9.32 GGT1 GGT2
11 regulation of immune system process GO:0002682 9.26 GGT1 GGT2
12 peptide modification GO:0031179 9.16 GGT1 GGT2
13 glutathione catabolic process GO:0006751 9.13 GGT1 GGT2 GGTLC3
14 leukotriene D4 biosynthetic process GO:1901750 8.8 GGT1 GGT2 GGTLC3

Molecular functions related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 9.16 ALB GPT
2 peptidyltransferase activity GO:0000048 8.96 GGT1 GGT2
3 glutathione hydrolase activity GO:0036374 8.8 GGT1 GGT2 GGTLC3

Sources for Hepatic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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