NANBH
MCID: HPT001
MIFTS: 63

Hepatitis C (NANBH)

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Infectious diseases, Liver diseases, Rare diseases, Skin diseases

Aliases & Classifications for Hepatitis C

MalaCards integrated aliases for Hepatitis C:

Name: Hepatitis C 12 74 54 42 43 15 37 71
Hepatitis C Infection 12 15
Hepatitis C, Chronic 71
Chronic Hepatitis C 12
Hepatitis Nona Nonb 12
Hepatitis C Chronic 54
Viral Hepatitis C 12
Nanbh 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1883
ICD9CM 34 070.7
MeSH 43 D006526
NCIt 49 C3098
SNOMED-CT 67 50711007
ICD10 32 B19.2 B19.20
UMLS 71 C0019196 C0524910

Summaries for Hepatitis C

MedlinePlus : 42 What is hepatitis C? Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. Inflammation can damage organs. There are different types of hepatitis. One type, hepatitis C, is caused by the hepatitis C virus (HCV). Hepatitis C can range from a mild illness lasting a few weeks to a serious, lifelong illness. Hepatitis C can be acute or chronic: Acute hepatitis C is a short-term infection. The symptoms can last up to 6 months. Sometimes your body is able to fight off the infection and the virus goes away. But for most people, an acute infection leads to chronic infection. Chronic hepatitis C is a long-lasting infection. If it is not treated, it can last for a lifetime and cause serious health problems, including liver damage, cirrhosis (scarring of the liver), liver cancer, and even death. How is hepatitis C spread? Hepatitis C spreads through contact with the blood of someone who has HCV. This contact may be through Sharing drug needles or other drug materials with someone who has HCV. In the United States, this is the most common way that people get hepatitis C. Getting an accidental stick with a needle that was used on someone who has HCV. This can happen in health care settings. Being tattooed or pierced with tools or inks that were not sterilized after being used on someone who has HCV Having contact with the blood or open sores of someone who has HCV Sharing personal care items that may have come in contact with another person's blood, such as razors or toothbrushes Being born to a mother with HCV Having unprotected sex with someone who has HCV Before 1992, hepatitis C was also commonly spread through blood transfusions and organ transplants. Since then, there has been routine testing of the U.S. blood supply for HCV. It is now very rare for someone to get HCV this way. Who is at risk for hepatitis C? You are more likely to get hepatitis C if you Have injected drugs Had a blood transfusion or organ transplant before July 1992 Have hemophilia and received clotting factor before 1987 Have been on kidney dialysis Were born between 1945 and 1965 Have abnormal liver tests or liver disease Have been in contact with blood or infected needles at work Have had tattoos or body piercings Have worked or lived in a prison Were born to a mother with hepatitis C Have HIV/AIDS Have had more than one sex partner in the last 6 months Have had a sexually transmitted disease Are a man who has had sex with men If you are at high risk for hepatitis C, your health care provider will likely recommend that you get tested for it. What are the symptoms of hepatitis C? Most people with hepatitis C have no symptoms. Some people with acute hepatitis C do have symptoms within 1 to 3 months after they are exposed to the virus. These symptoms may include Dark yellow urine Fatigue Fever Gray- or clay-colored stools Joint pain Loss of appetite Nausea and/or vomiting Pain in your abdomen Jaundice (yellowish eyes and skin) If you have chronic hepatitis C, you probably will not have symptoms until it causes complications. This can happen decades after you were infected. For this reason, hepatitis C screening is important, even if you have no symptoms. What other problems can hepatitis C cause? Without treatment, hepatitis C may lead to cirrhosis, liver failure, and liver cancer. Early diagnosis and treatment of hepatitis C can prevent these complications. How is hepatitis C diagnosed? Health care providers diagnose hepatitis C based on your medical history, a physical exam, and blood tests. If you do have hepatitis C, you may need additional tests to check for liver damage. These tests may include other blood tests, an ultrasound of the liver, and a liver biopsy. What are the treatments for hepatitis C? Treatment for hepatitis C is with antiviral medicines. They can cure the disease in most cases. If you have acute hepatitis C, your health care provider may wait to see if your infection becomes chronic before starting treatment. If your hepatitis C causes cirrhosis, you should see a doctor who specializes in liver diseases. Treatments for health problems related to cirrhosis include medicines, surgery, and other medical procedures. If your hepatitis C leads to liver failure or liver cancer, you may need a liver transplant. Can hepatitis C be prevented? There is no vaccine for hepatitis C. But you can help protect yourself from hepatitis C infection by Not sharing drug needles or other drug materials Wearing gloves if you have to touch another person's blood or open sores Making sure your tattoo artist or body piercer uses sterile tools and unopened ink Not sharing personal items such toothbrushes, razors, or nail clippers Using a condom when you have sex NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Hepatitis C, also known as hepatitis c infection, is related to hepatitis c virus and viral hepatitis, and has symptoms including fever, vomiting and fatigue. An important gene associated with Hepatitis C is MIR122 (MicroRNA 122), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Acarbose and Insulin glulisine have been mentioned in the context of this disorder. Affiliated tissues include Blood, liver and testes, and related phenotype is Decreased interferon-beta reporter expression.

Disease Ontology : 12 A viral infectious disease that results in inflammation located in liver, has material basis in Hepatitis C virus, which is transmitted by blood from an infected person enters the body of an uninfected person. The infection has symptom fever, has symptom fatigue, has symptom loss of appetite, has symptom nausea, has symptom vomiting, has symptom abdominal pain, has symptom clay-colored bowel movements, has symptom joint pain, and has symptom jaundice.

Wikipedia : 74 Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the... more...

Related Diseases for Hepatitis C

Diseases in the Hepatitis family:

Hepatitis C Virus Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis B Hepatitis D
Autoimmune Hepatitis Hepatitis E
Autoimmune Hepatitis Type 2 Autoimmune Hepatitis Type 1

Diseases related to Hepatitis C via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1300)
# Related Disease Score Top Affiliating Genes
1 hepatitis c virus 34.4 SCARB1 KRT18 IRF3 IFNG GPT EIF2AK2
2 viral hepatitis 33.0 MX1 MIR122 KRT18 IFNG IFNA2 IFNA1
3 hepatitis 32.6 SCARB1 MAVS KRT18 IRF3 IFNG IFNA2
4 cryoglobulinemia, familial mixed 32.4 IFNA2 IFNA1
5 cryoglobulinemia 32.3 IFNG IFNA2 IFNA1 GPT CXCL10 CD81
6 immune deficiency disease 32.0 IFNG IFNA1 GPT CXCL10 CD81
7 liver cirrhosis 31.9 MIR122 KRT18 IFNA2 IFNA1 HOTAIR GPT
8 hepatitis b 31.9 MX1 IFNG IFNB1 IFNA2 IFNA1 GPT
9 autoimmune hepatitis 31.9 KRT18 IFNA1 GPT
10 hepatitis a 31.8 MAVS IFNG IFNA2 IFNA1 GPT CXCL10
11 hepatitis d 31.7 IFNA2 IFNA1 GPT EIF2AK2
12 thrombocytopenia 31.7 IFNG IFNB1 IFNA2 IFNA1 GPT CXCL10
13 vaccinia 31.5 IRF3 IFNB1 IFNA1 EIF2AK2
14 hypothyroidism 31.5 IFNB1 IFNA2 IFNA1 GPT CXCL10
15 human immunodeficiency virus type 1 31.5 IRF3 IFNG IFNA1 CXCL10
16 hepatitis e 31.4 MIR122 IFNG GPT DDX58
17 stomatitis 31.2 MX1 IFNG IFNA2 IFNA1 EIF2AK2 DDX58
18 west nile virus 31.2 IRF3 IFNA1 DDX58
19 encephalitis 31.0 MX1 IRF3 DDX58 CXCL10
20 herpes simplex 31.0 IRF3 IFNB1 IFNA1 EIF2AK2 DDX58
21 oral erosive lichen 30.9 IFNB1 IFNA1
22 kaposi sarcoma 30.8 IRF3 IFNB1 IFNA2 IFNA1
23 herpes zoster 30.8 IFNG IFNA2 IFNA1
24 tick-borne encephalitis 30.7 IFNB1 GPT DDX58 CXCL10
25 cutaneous lupus erythematosus 30.6 MX1 IFNG IFNA1
26 rubella 30.6 IFNG IFNB1 GPT DDX58
27 systemic lupus erythematosus 30.6 MX1 IRF3 IFNG IFNB1 IFNA1 DDX58
28 measles 30.6 IRF3 IFNG IFNB1 IFNA1 EIF2AK2 DDX58
29 viral infectious disease 30.6 MX1 MIR122 MAVS IRF3 IFNG IFNB1
30 uveitis 30.6 IFNG IFNA2 CXCL10
31 rabies 30.6 MX1 IRF3 IFNA1 DDX58 CXCL10
32 biliary atresia 30.6 MX1 IFNG GPT
33 lymphocytic choriomeningitis 30.5 MAVS IRF3 DDX58
34 cutaneous t cell lymphoma 30.5 IFNG IFNA2 IFNA1 CXCL10
35 severe acute respiratory syndrome 30.5 MX1 IRF3 IFNG IFNB1 IFNA1 GPT
36 demyelinating disease 30.5 IFNG IFNB1 IFNA1 CXCL10
37 venezuelan equine encephalitis 30.4 IFNG IFNB1 IFNA1 CXCL10
38 mouth disease 30.4 MX1 IRF3 IFNG IFNA1 DDX58
39 pyelonephritis 30.4 IFNG GPT CXCL10
40 mycosis fungoides 30.4 IFNG IFNA2 IFNA1 CXCL10
41 trypanosomiasis 30.4 IFNG GPT CXCL10
42 hypereosinophilic syndrome 30.4 IFNG IFNA2 IFNA1
43 discoid lupus erythematosus 30.2 IFNA2 IFNA1
44 newcastle disease 30.2 IRF3 IFNB1 IFNA1 EIF2AK2 DDX58 CXCL10
45 malaria 30.1 SCARB1 IFNG IFNB1 IFNA1 GPT CXCL10
46 avian influenza 30.1 IFNA1 DDX58 CXCL10
47 influenza 30.1 MX1 MAVS IRF3 IFNG IFNB1 IFNA1
48 kidney cancer 30.0 MIR122 IFNG IFNA2 IFNA1 HOTAIR
49 argentine hemorrhagic fever 30.0 IRF3 DDX58
50 mumps 29.8 MX1 IFNG IFNB1 IFNA1 EIF2AK2 CXCL10

Graphical network of the top 20 diseases related to Hepatitis C:



Diseases related to Hepatitis C

Symptoms & Phenotypes for Hepatitis C

Symptoms:

12
  • fever
  • vomiting
  • fatigue
  • abdominal pain
  • jaundice
  • nausea
  • loss of appetite
  • joint pain
  • clay-colored bowel movements

GenomeRNAi Phenotypes related to Hepatitis C according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased interferon-beta reporter expression GR00307-A 8.92 EIF2AK2 GPT IRF3 MAVS

Drugs & Therapeutics for Hepatitis C

Drugs for Hepatitis C (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 603)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
2
Insulin glulisine Approved Phase 4 207748-29-6
3
Insulin glargine Approved Phase 4 160337-95-1
4
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
5
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
6
Losartan Approved Phase 4 114798-26-4 3961
7
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
8
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
9
Polyestradiol phosphate Approved Phase 4 28014-46-2
10
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
11
Abacavir Approved, Investigational Phase 4 136470-78-5 65140 441300
12
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
13
Citalopram Approved Phase 4 59729-33-8 2771
14
Colchicine Approved Phase 4 64-86-8 6167 2833
15
Infliximab Approved Phase 4 170277-31-3
16
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
17
Promethazine Approved, Investigational Phase 4 60-87-7 4927
18
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
19
Didanosine Approved Phase 4 69655-05-6 50599
20
Zidovudine Approved Phase 4 30516-87-1 35370
21
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 7045767
22
Fosamprenavir Approved Phase 4 226700-79-4 131536
23
chloroquine Approved, Investigational, Vet_approved Phase 4 54-05-7 2719
24
Nelfinavir Approved Phase 4 159989-64-7 64143
25
Basiliximab Approved, Investigational Phase 4 152923-56-3, 179045-86-4
26
Baclofen Approved Phase 4 1134-47-0 2284
27
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
28
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
29
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
30 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
31
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
32
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833
33
Insulin aspart Approved Phase 4 116094-23-6 16132418
34
Insulin detemir Approved Phase 4 169148-63-4 5311023
35
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
36
Cobicistat Approved Phase 4 1004316-88-4
37
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
38
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
39
Topiramate Approved Phase 4 97240-79-4 5284627
40
Isoniazid Approved, Investigational Phase 4 54-85-3 3767
41
Rifapentine Approved, Investigational Phase 4 61379-65-5 6323497
42
Azathioprine Approved Phase 4 446-86-6 2265
43
Lenvatinib Approved, Investigational Phase 4 417716-92-8
44
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
45
Methadone Approved Phase 4 76-99-3 4095
46
Methylcobalamin Approved, Investigational Phase 4 13422-55-4
47
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 15589840
48
tannic acid Approved Phase 4 1401-55-4
49
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
50
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189

Interventional clinical trials:

(show top 50) (show all 2620)
# Name Status NCT ID Phase Drugs
1 The Response and Outcomes of Pegylated Interferon Plus Ribavirin Combination Therapy for Chronic Hepatitis C Patients Concomitant With Hepatocellular Carcinoma Unknown status NCT00834860 Phase 4 peginterferon alpha-2a and ribavirin
2 Efficacy and Safety of Daclatasvir Plus Asunaprevir Treatment in Patients With Chronic Hepatitis C : Prospective Cohort Study Unknown status NCT02639585 Phase 4 Daclinza and Sunvepra
3 A Phase 4, Open-Label Study to Investigate the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 and 4 HCV Infection With Autoimmune Disease Unknown status NCT02691728 Phase 4 LDV/SOF FDC
4 A Randomized, Multi-center, Phase IV Open-label Study Evaluating the Antiviral Efficacy of Addition of Vitamin D in Patients With Treatment Naïve Chronic Hepatitis C Receiving Peginterferon Alfa-2a Plus Ribavirin Unknown status NCT01439776 Phase 4
5 Hepatitis C in Renal Transplant Recipients - Safety and Efficacy of a Conversion of Immunosuppression to High-dose Cyclosporine A and Its Impact on Hepatitis C Virus-replication, Parameters of Liver Function and Glucose Tolerance. An Open Label Trial. Unknown status NCT02108301 Phase 4 tacrolimus-cyclosporine A
6 Treatment of Chronic Hepatitis C Patients With Persistently Normal Alanine Aminotransferase Levels With Peginterferon α-2a (40 kDa) Plus Ribavirin Unknown status NCT00575627 Phase 4 Peg-Interferon alpha2a plus Ribavirin
7 An Open-Label Study to Evaluate Long-Term Outcomes With Ombitasvir-Paritaprevir-Ritonavir and Dasabuvir With or Without Ribavirin (RBV) in Fertile Women With Genotype 1 and 4 Chronic Hepatitis C Virus (HCV) Infection Unknown status NCT02950870 Phase 4 Ombitasvir-Paritaprevir-Ritonavir;Dasabuvir;Ribavirin
8 Hepatic Safety of Raltegravir-based and Efavirenz-based Antiretroviral Regimens in Antiretroviral-Naïve HIV-infected Subjects Co-Infected With Hepatitis C Unknown status NCT01147107 Phase 4 Raltegravir;Efavirenz
9 Pilot Treatment as Prevention for HCV Among Persons Who Actively Inject Drugs Unknown status NCT02609893 Phase 4
10 Randomized, Multi-Center, Partially Placebo-Controlled Phase IV-Study to Compare Efficacy and Tolerability of 48-Week Combined Therapy With Peginterferon Alfa-2a, Ribavirin and Amantadine Sulphate Versus Placebo in Untreated Patients With Chronic Hepatitis C Virus-Genotype-1-Infection Unknown status NCT00127777 Phase 4 Amantadine sulphate (in addition to standard treatment)
11 Efficacy and Safety of a Hansenula-derived Pegylated Interferon α2a (Reiferon Retard®) in Treatment of Patients With Chronic Hepatitis C Virus Infection: A National Multi-center Phase IV Open Label Non-Randomized Trial Unknown status NCT01649245 Phase 4 Reiferon retard
12 A Prospective Randomized, Open Labeled, Phase IV, Multicenter Study for Peginterferon Alfa-2a and Weight-based Ribavirin for 16 or 24 Weeks in genotype2 Chronic Hepatitis C Patients Who Achieved Rapid Virologic Response Unknown status NCT01056172 Phase 4 Peginterferon alfa-2a and Ribavirin;Peginterferon alfa-2a and Ribavirin
13 Safety and Effect of Elbasvir/Grazoprevir Combination Therapy in Hemodialysis Patients With Chronic Hepatitis C Unknown status NCT03022006 Phase 4 elbasvir, grazoprevir
14 Open, Multicentre,Randomized Phase IV Trial to Evaluate Efficacy/Safety to Extend Treatment Duration With Peginterferon Alfa-2a+High Dose of Ribavirin Supporting Epo β in Treatment of CHC in HIV-HCV Patients Who Not Clear Virus at Week 4 Unknown status NCT00526448 Phase 4 ribavirin;ribavirin;Peginterferon alfa-2a;epoetin beta
15 Pilot Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection in Liver Transplant Candidates (EZE-2) Unknown status NCT02768545 Phase 4 Ezetimibe
16 Open, Randomized and Multicenter Phase IV Study to Compare the Efficacy and Safety of Two Different Treatments Duration 24 Versus 48 Weeks in Chronic Hepatitis C Genotypes 2 and/or 3 co-Infected HIV-HCV Patients. Unknown status NCT00611819 Phase 4 Peg interferon + Ribavirin;Peg interferon + Ribavirin
17 An Efficacy and Safety Study Comparing Pegylated-Interferon and Ribavirin Plus Metformin to Pegylated-Interferon and Ribavirin in the Treatment of naïve Patients With Genotype 1 Chronic HCV Infection and Insulin Resistance Unknown status NCT00370617 Phase 4 metformin
18 A Single Center, Prospective Phase IV, Open-Label, Randomized Trial Comparing the Efficacy , Tolerability, and Safety of Quadritherapy Regimen (Reiferon Retard® + Ribavirin + Nitazoxanide + Alfacalcidol ( Bon-One ®) ) Versus Triple Therapy Regimen (Reiferon Retard® + Ribavirin + Nitazoxanide) Versus the Standard of Care Regimen(Reiferon Retard® + Ribavirin) in the Treatment of Naïve Chronic Hepatitis- C Among the Egyptian Population. Effectiveness Will be Evaluated Based on Sustained Viral Response (SVR) Unknown status NCT01896609 Phase 4 Bon one in Arm 3;Xerovirinc in Arm 2;Ribavirin in Arm 1
19 A Pilot Study to Treat Patients With Chronic HCV Genotype 1 and ESRD Receiving Hemodialysis and Naïve to Prior HCV Therapy With Peginterferon Alfa-2b, the Maximally Tolerated Ribavirin Dose and Boceprevir Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
20 An Open-label, Multi-center, Randomized Study Comparing the Effects of Oral Hypoglycemic Agents on Viral Kinetics of Chronic Hepatitis C Patients Receiving Pegylated Interferon Alfa 2b Plus Ribavirin Unknown status NCT01025765 Phase 4 Pioglitazone;Acarbose;Metformin
21 Curing HCV in Incarcerated Patients Unknown status NCT03018353 Phase 4 Patients receiving Sof/Vel (Epclusa) and Navigation services
22 Direct Observed Therapy With Ledipasvir/Sofosbuvir in Treatment-naïve Patients With Chronic Genotype 1 HCV (Hepatitis C Virus) Infection Receiving Opiate Substitution Therapy Unknown status NCT02638233 Phase 4 Sofosbuvir 400mg / Ledipasvir 90 mg (FDC)
23 A Monocenter Randomized Double-blind Placebo-controlled Study to Investigate Neuropsychiatric Manifestations of HCV-infection During and After Treatment With Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Unknown status NCT03003338 Phase 4 OBV/PTV/r and DSV;Placebo to match OBV/PTV/r and DSV
24 Personalized Medicine in HCV Infection: Cognitive Impairments and Brain Anomalies in Chronic Hepatitis C Infected Individuals. Characterization and Potential Reversibility With Direct Antiviral Agents. Unknown status NCT02745132 Phase 4
25 Phase IV Study of Effectiveness of Interferon and Ribavirin Treatment in Thalassemia Major Patients With Chronic Viral Hepatitis C Unknown status NCT00887081 Phase 4 PEG-IFN alpha2a or PEG-IFN alpha2b and Ribavirin
26 Toward Elimination of Hepatitis C Virus (HCV): A Pilot Study Combining HCV and Addiction Treatment of Young Suburban Heroin Users (SHU) That Addresses Barriers to Care Unknown status NCT03364725 Phase 4 Glecaprevir-pibrentasvir
27 Development of an Imaging Biomarker for Hepatic Fibrosis Using Gadoxetate Disodium Unknown status NCT01783314 Phase 4
28 An Open Label, Randomized, Parallel Design Estimation Pilot Study to Compare the Effectiveness of 36 vs 48 Wks PegIntron Plus Ribavirin Treatment for HCV Patients Without Rapid Virologic Response(RVR) But With Undetectable HCV RNA at wk 8 Unknown status NCT01683786 Phase 4 Pegintron + Riba
29 Personalized Medicine in HCV Chronic Infection. Endothelial Dysfunction and Subclinical Atheromatosis in Patients With HCV Infection. Characterization and Potential Reversibility With Direct Antiviral Agents. Unknown status NCT02802280 Phase 4
30 Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis B Unknown status NCT00597259 Phase 4 Pegasys plus Entecavir;Entecavir
31 A Pilot Study to Evaluate the Efficacy and Safety of Pegylated Interferon Alfa-2b Plus Ribavirin in the Treatment of Patients With Dual Chronic Hepatitis B and Delta Unknown status NCT00117533 Phase 4 pegylated IFN alfa-2b plus ribavirin
32 Pegasys Plus Entecavir Versus Entecavir Versus Pegasys for Hepatitis B e Antigen-Negative Chronic Hepatitis B Unknown status NCT01925820 Phase 4 Pegasys&Entecavir
33 Grazoprevir/Elbasvir for Treatment of Hepatitis C Virus Genotype 4 Post Kidney Transplant Unknown status NCT03359746 Phase 4 Grazoprevir/Elbasvir
34 A Pilot Study to Assess the Efficacy and Safety of Folic Acid and/or Vitamin B Complex on Hepatitis C Infected Patients Treated With Pegylated Interferon and Ribavirin. Unknown status NCT02150291 Phase 4 Neurobion;placebo
35 The Effects of Preventive Versus on Demand Nutritional Advice and Support on the Nutritional Status of Patients During Antiviral Therapy for Hepatitis C A Randomized, Multi Center Trial Unknown status NCT00841243 Phase 4
36 Efficacy of Pentoxyfylline Addition to a Treatment Scheme Based on Interferon Alpha and Ribavirin on Hepatitis C Virus Coinfected HIV Patients, Considering Interleukin 28B Polymorphism rs12979860 Unknown status NCT02008214 Phase 4 Pentoxifylline;Placebo
37 An Open-label, Randomised Pilot Study Comparing the Efficacy, Safety and Tolerability of Raltegravir With Protease Inhibitor-based Therapy in Treatment-naïve, HIV/Hepatitis C Co-infected Injecting Drug Users Receiving Methadone Unknown status NCT01105611 Phase 4 Raltegravir;Atazanavir/Ritonavir
38 Telaprevir in Patients With Genotype 3 HCV: Pilot Clinical Study to Evaluate Efficacy and Predictability of Therapy in Patients Who Have Failed to Respond to Pegylated Interferon and Ribavirin Unknown status NCT02087111 Phase 4 Telaprevir;40 Kd Pegylated interferon alfa 2a;Ribavirin
39 Insulin Therapy in the Inpatient Management of Cirrhotic Patients With Type 2 Diabetes Unknown status NCT01143948 Phase 4 Glargine & Glulisine;Regular insulin;NPH & regular insulin
40 Effect Of Interferon-Free Direct Acting Antiviral Agents For Treatment Of Hepatitis C Virus Patients On The Normal Kidney Unknown status NCT03296930 Phase 4 Sofosbuvir 400 MG Oral Tablet,;Ombitasvir/paritaprevir/ritonavir
41 The Employing of the Bio-Hep-B PreS1/PreS2/S Hepatitis B Virus (HBV) Vaccine in New Born Babies From HBV Positive Palestinian Mothers Unknown status NCT01133184 Phase 4
42 Safety and Efficacy of Immunosuppression With Basiliximab, Delayed Dose Tacrolimus Plus Enteric Coated Mycophenolic Acid, Versus Standard Dose Tacrolimus, Enteric Coated Mycophenolic Acid Plus Corticosteroids in Patients Undergoing Orthotopic Liver Transplantation (OLT) Unknown status NCT02123108 Phase 4 Basiliximab
43 Non-randomized Prospective Study on the Effect of Antiviral Therapy With Peginterferon Alfa-2a and Ribavirin on Bone Mineral Density and Metabolism in Patients With Chronic Viral Hepatitis C Genotype 1 Completed NCT00948220 Phase 4 peginterferon alfa-2a and ribavirin
44 Pharmacovigilance Study of the Interferon α 2b Produced by Bio-Manguinhos / Fiocruz and Used by Genotype 2/3 Chronic Hepatitis C Patients (Estudo de farmacovigilância da Alfainterferona 2b Humana Recombinante Produzida Por Bio-Manguinhos - Fiocruz, Utilizada em Portadores de Hepatite C crônica genótipos 2 e 3 Atendidos Pelo Programa de Medicamentos de Dispensação em Caráter Excepcional no Estado do Rio de Janeiro) Completed NCT01841775 Phase 4 interferon α 2b + ribavirin
45 Efficacy and Safety of Neutrino Therapy for Chronic HCV Genotype 1b Treatment-experienced Patients Completed NCT02480686 Phase 4 SOF+PEG+RBV
46 Efficacy and Safety Study of Sofosbuvir Containing Regimens in Subjects With Chronic Hepatitis C Virus Genotype 2 Infection Completed NCT02482077 Phase 4 SOF+RBV;SOF+DCV;LDV/SOF
47 Sofosbuvir, Ribavirin, for the Treatment of Chronic Hepatitis C Virus Genotype 1 in HIV-Coinfected Patients Receiving Fixed Dose Co-formulation Emtricitabine/ Tenofovir/Cobicistat/Elvitegravir: A Pilot Study Completed NCT02220868 Phase 4 Sofosbuvir, Ribavirin, and Stribild
48 An International, Multi-Center Study Evaluating the Correlation of IL28B Genotypes With Patient Demographics and Disease Characteristics in Patients With Chronic Hepatitis C Completed NCT01675427 Phase 4
49 The Response and Outcomes of Pegylated Interferon Plus Ribavirin Combination Therapy for Chronic Hepatitis C Patients Concomitant With Malignancy Other Than Hepatocellular Carcinoma Completed NCT00630084 Phase 4 pegylated interferon alpha 2a and plus ribavirin;pegylated interferon alpha 2a and plus ribavirin
50 Effect of Long-Term Administration of Oral Losartan on Hepatic Fibrogenesis and Gene Expression in Chronic Hepatitis C With Significant Liver Fibrosis. Completed NCT00298714 Phase 4 Losartan

Search NIH Clinical Center for Hepatitis C

Inferred drug relations via UMLS 71 / NDF-RT 50 :


boceprevir
daclatasvir
dasabuvir
elbasvir
grazoprevir
Hepatitis C Virus Non-Nucleoside NS5B Palm Polymerase Inhibitor [EPC]
Hepatitis C Virus NS3/4A Protease Inhibitor [EPC]
Hepatitis C Virus NS5A Inhibitor [EPC]
Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor [EPC]
Interferon Alfa-2a
Interferon Alfa-2b
INTERFERON ALFA-3N,HUMAN LEUKOCYTE DERIVED
interferon alfacon-1
Interferon gamma-1b
Interferons
ledipasvir
ombitasvir
paritaprevir
PEGINTERFERON
peginterferon alfa-2a
peginterferon alfa-2b
Recombinant interferon beta-1a
Recombinant interferon beta-1b
Ribavirin
simeprevir
sofosbuvir
telaprevir
velpatasvir

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Hepatitis C cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Hepatitis C:
Autologous hematopoietic stem cells for treatment of end-stage chronic liver disease
Embryonic/Adult Cultured Cells Related to Hepatitis C:
Peripheral blood-derived hematopoietic stem cells PMIDs: 20587151

Cochrane evidence based reviews: hepatitis c

Genetic Tests for Hepatitis C

Anatomical Context for Hepatitis C

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatitis C:

19
Liver

MalaCards organs/tissues related to Hepatitis C:

40
Liver, Testes, Kidney, T Cells, B Cells, Thyroid, Bone
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Hepatitis C:
# Tissue Anatomical CompartmentCell Relevance
1 Blood Hematopoietic Bone Marrow Hematopoietic Stem Cells Potential therapeutic candidate

Publications for Hepatitis C

Articles related to Hepatitis C:

(show top 50) (show all 32842)
# Title Authors PMID Year
1
Hepatitis C. 42 61
31631857 2019
2
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