MCID: HPT007
MIFTS: 55

Hepatitis E

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Infectious diseases, Liver diseases, Rare diseases, Skin diseases

Aliases & Classifications for Hepatitis E

MalaCards integrated aliases for Hepatitis E:

Name: Hepatitis E 12 77 54 56 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4411
MeSH 45 D016751
UMLS 74 C0085293

Summaries for Hepatitis E

Disease Ontology : 12 A viral infectious disease that results in inflammation located in liver, has material basis in Hepatitis E virus, which is transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom fatigue, has symptom loss of appetite, has symptom nausea, has symptom vomiting, has symptom abdominal pain, has symptom clay-colored bowel movements, has symptom dark urine, has symptom joint pain, and has symptom jaundice.

MalaCards based summary : Hepatitis E is related to infantile liver failure syndrome 1 and acute liver failure, and has symptoms including fever, vomiting and fatigue. An important gene associated with Hepatitis E is GPT (Glutamic--Pyruvic Transaminase), and among its related pathways/superpathways are NF-kappaB Signaling and Colorectal Cancer Metastasis. The drugs Aluminum sulfate and Aluminum hydroxide have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and testes, and related phenotypes are endocrine/exocrine gland and reproductive system

Wikipedia : 77 Hepatitis E is inflammation of the liver caused by infection with the hepatitis E virus. It is one of... more...

Related Diseases for Hepatitis E

Diseases in the Hepatitis family:

Hepatitis C Virus Autoimmune Hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Hepatitis E via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 215)
# Related Disease Score Top Affiliating Genes
1 infantile liver failure syndrome 1 30.9 ALB F2 GPT
2 acute liver failure 30.8 ALB F2 GPT
3 viral hepatitis 30.5 ALB F2 GPT TNF
4 hepatitis a 30.3 ALB F2 GPT IFNG TNF
5 liver disease 30.2 ALB F2 GPT TNF
6 hepatitis c 30.1 GPT IFNG TLR3 TNF
7 hepatitis b 30.0 ALB F2 GPT IFNG TNF
8 hepatitis d 29.7 F2 GPT
9 hepatic coma 29.6 ALB F2 GPT
10 cholecystitis 29.6 ALB F2 GPT
11 bilirubin metabolic disorder 29.6 ALB F2 GPT
12 typhoid fever 29.6 ALB F2 IFNG TNF
13 leptospirosis 29.5 F2 IFNG TNF
14 alcoholic hepatitis 29.5 ALB F2 GPT TNF
15 cholangitis 29.5 ALB F2 GPT TNF
16 meningitis 29.4 ALB IFNG TNF
17 hepatic encephalopathy 29.2 ALB F2 GPT TNF
18 human immunodeficiency virus type 1 29.2 IFNG TLR3 TNF TSG101
19 schistosomiasis 29.0 ALB CD40LG F2 IFNG TNF
20 hepatitis 11.3
21 hepatoportal sclerosis 10.3 F2 GPT
22 antipyrine metabolism 10.3 ALB F2
23 non-a-e hepatitis 10.3 ALB F2
24 epstein-barr virus hepatitis 10.3 ALB F2
25 variola major 10.3 IFNG TLR3
26 guillain-barre syndrome 10.3
27 abdominal tuberculosis 10.2 ALB F2
28 staphylococcal toxic shock syndrome 10.2 IFNG TNF
29 marburg hemorrhagic fever 10.2 F2 TNF
30 autoimmune myocarditis 10.2 IFNG TNF
31 adult dermatomyositis 10.2 GPT TNF
32 trichosporonosis 10.2 IFNG TNF
33 chronic beryllium disease 10.2 IFNG TNF
34 opisthorchiasis 10.2 GPT TNF
35 scleritis 10.2 IFNG TNF
36 african tick-bite fever 10.2 CD40LG IFNG
37 amyotrophic neuralgia 10.2
38 miliary tuberculosis 10.2 IFNG TNF
39 sporotrichosis 10.2 CD40LG IFNG
40 hepatic tuberculosis 10.1 ALB F2 GPT
41 mucocutaneous leishmaniasis 10.1 TLR3 TNF
42 kwashiorkor 10.1 ALB F2 GPT
43 acute pancreatitis 10.1
44 pancreatitis 10.1
45 burns 10.1 ALB TNF
46 choledocholithiasis 10.1 ALB F2 GPT
47 analbuminemia 10.1 ALB F2 GPT
48 bile duct disease 10.1 ALB F2 GPT
49 clonorchiasis 10.1 IFNG TNF
50 fascioliasis 10.1 ALB GPT IFNG

Graphical network of the top 20 diseases related to Hepatitis E:



Diseases related to Hepatitis E

Symptoms & Phenotypes for Hepatitis E

Symptoms:

12
  • fever
  • vomiting
  • fatigue
  • abdominal pain
  • jaundice
  • nausea
  • joint pain
  • loss of appetite
  • clay-colored bowel movements
  • dark urine

MGI Mouse Phenotypes related to Hepatitis E:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.56 ALB AMBP CD40LG FGB IFNG TLR3
2 reproductive system MP:0005389 9.17 AMBP CD40LG F2 FGB IFNG TLR3

Drugs & Therapeutics for Hepatitis E

Drugs for Hepatitis E (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aluminum sulfate Approved Phase 4,Phase 3 10043-01-3
2
Aluminum hydroxide Approved, Investigational Phase 4,Phase 3,Phase 1 21645-51-2
3
Ribavirin Approved Phase 4,Phase 2 36791-04-5 37542
4 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
5 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
6 Antiviral Agents Phase 4,Phase 2,Not Applicable
7 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
8 Antimetabolites Phase 4,Phase 2
9
Nicotinamide Approved, Investigational Phase 2, Phase 3,Phase 3 98-92-0 936
10
Milk thistle Approved, Experimental, Investigational Phase 2, Phase 3 65666-07-1
11
Niacin Approved, Investigational, Nutraceutical Phase 2, Phase 3,Phase 3 59-67-6 938
12
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3,Phase 3 70-16-6, 59-43-8 1130
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
14
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3 83-88-5 493570
15 Nicotinic Acids Phase 2, Phase 3
16 Antioxidants Phase 2, Phase 3
17 Trace Elements Phase 2, Phase 3
18 Vitamins Phase 2, Phase 3
19 Vitamin B Complex Phase 2, Phase 3
20 Vitamin B9 Phase 2, Phase 3
21 Vitamin B2 Phase 2, Phase 3
22 Protective Agents Phase 2, Phase 3
23 silymarin Phase 2, Phase 3
24 Vitamin B3 Phase 2, Phase 3
25 Nutrients Phase 2, Phase 3
26 Folate Phase 2, Phase 3
27 Thiamin Phase 2, Phase 3
28 Micronutrients Phase 2, Phase 3
29
Sofosbuvir Approved Phase 2 1190307-88-0 45375808
30
Peginterferon alfa-2a Approved, Investigational Phase 2 198153-51-4 5360545
31
Entecavir Approved, Investigational Phase 2,Not Applicable 142217-69-4 153941
32 Liver Extracts Phase 2,Phase 1
33 interferons Phase 2
34
Tacrolimus Approved, Investigational Phase 1 104987-11-3 6473866 445643 439492
35
Basiliximab Approved, Investigational Phase 1 179045-86-4, 152923-56-3
36 Pharmaceutical Solutions Phase 1
37 Immunosuppressive Agents Phase 1
38
Permethrin Approved, Investigational Not Applicable 52645-53-1 40326
39 Antibodies
40 Immunoglobulins

Interventional clinical trials:

(show all 34)
# Name Status NCT ID Phase Drugs
1 A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule) Completed NCT03168412 Phase 4
2 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients ) Completed NCT02964910 Phase 4
3 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli) Completed NCT02417597 Phase 4
4 Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®) Completed NCT02189603 Phase 4
5 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine) Completed NCT02584543 Phase 4
6 Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh. Active, not recruiting NCT02759991 Phase 4 Hecolin;Hepa-B
7 Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection. Terminated NCT02558114 Phase 4 Ribavirin
8 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Withdrawn NCT03365921 Phase 4
9 Clinical Trial of Recombinant Hepatitis E Vaccine Unknown status NCT01014845 Phase 3
10 Field Trial of Maternal Influenza Immunization in Asia Unknown status NCT01034254 Phase 3
11 Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )Vaccine Active, not recruiting NCT01735006 Phase 3
12 Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis Terminated NCT00755950 Phase 2, Phase 3
13 A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus Unknown status NCT01698723 Phase 2 Ribavirin;Placebo
14 HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE) Completed NCT03282474 Phase 2 Sofosbuvir
15 Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen Completed NCT01204762 Phase 2 pegIFN;pegIFNα-2a;PegIFN lambda;Entecavir
16 Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine Active, not recruiting NCT02710851 Phase 2
17 Study of rADAMTS-13 (SHP655) in the Treatment of Participants With Acquired Thrombotic Thrombocytopenic Purpura (aTTP) Not yet recruiting NCT03922308 Phase 2 SHP655
18 A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal. Withdrawn NCT00287469 Phase 2
19 A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy Adults Completed NCT02603055 Phase 1
20 Safety Study of Hepatitis E Vaccine (HEV239) in Healthy US Adult Population Recruiting NCT03827395 Phase 1
21 Safety and Tolerance of Immunomodulating Therapy With Donor-specific MSC in Pediatric Living-Donor Liver Transplantation Recruiting NCT02957552 Phase 1
22 The Epidemiology of Hepatitis E Virus Infection in Israel and Potential Risk Factors Unknown status NCT02419625 Not Applicable
23 Epidemiological Study of Hepatitis E Virus in Maintenance Hemodialysis Patients Unknown status NCT02645955
24 Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille. Unknown status NCT02819128 Not Applicable
25 Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb) Completed NCT02847507
26 Seroprevalence of Hepatitis E in People With an Organ Transplant Completed NCT02190253
27 Role of Cytokines in Hepatitis E Virus Infection During Pregnancy Completed NCT01062321
28 Host Responses in Kidney-transplant Recipients With Chronic Hepatitis E Virus Infection Completed NCT01090232 Not Applicable
29 Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy Completed NCT01858519
30 Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110E Completed NCT01813487 Not Applicable HBsAg vaccine with Entecavir
31 Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study Recruiting NCT02809885 Not Applicable
32 Hepatitis E Infection : Emergence Mechanisms in North-Eastern France of Polymorphic Clinical Forms. Recruiting NCT03524014
33 Seroprevalence Hepatitis E Infection in Healthy Blood Donors Recruiting NCT03601221
34 HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for Liver Not yet recruiting NCT03488589

Search NIH Clinical Center for Hepatitis E

Cochrane evidence based reviews: hepatitis e

Genetic Tests for Hepatitis E

Anatomical Context for Hepatitis E

MalaCards organs/tissues related to Hepatitis E:

42
Liver, Kidney, Testes, T Cells, Thyroid, B Cells, Heart

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatitis E:

20
Liver

Publications for Hepatitis E

Articles related to Hepatitis E:

(show top 50) (show all 3073)
# Title Authors Year
1
Acute liver failure and misdiagnosis: Do not forget viral hepatitis E. ( 30017940 )
2019
2
Case Report: Acute Hepatitis E in a Pediatric Traveler Presenting with Features of Autoimmune Hepatitis: A Diagnostic and Therapeutic Challenge. ( 30350777 )
2019
3
Chronic Hepatitis E is associated with Cholangitis. ( 31102493 )
2019
4
Guillain-Barré syndrome in a patient of acute Hepatitis E virus infection associated with genotype 1: Case report and literature review. ( 30881857 )
2019
5
Hepatitis E during pregnancy: maternal and fetal case-fatality rates and adverse outcomes - a systematic review. ( 31095813 )
2019
6
Viral load and clinical manifestations of hepatitis E virus genotype 3 infections. ( 31099059 )
2019
7
Hepatitis E Virus Infections Among HIV-Positive Individuals During an Outbreak of Acute Hepatitis A in Taiwan. ( 31100186 )
2019
8
Hepatitis E Virus Infection in European Brown Hares, Germany, 2007-2014. ( 31107217 )
2019
9
Epidemiology of Hepatitis E in England and Wales: A 10-Year Retrospective Surveillance Study, 2008-2017. ( 31107958 )
2019
10
The Burden of Hepatitis E among Patients with Hematological Malignancies: a Retrospective European Cohort Study. ( 31108159 )
2019
11
Successful Establishment of Hepatitis E Virus Infection in Pregnant BALB/c Mice. ( 31108901 )
2019
12
The Current Host Range of Hepatitis E Viruses. ( 31108942 )
2019
13
Genetic Variability and Evolution of Hepatitis E Virus. ( 31109076 )
2019
14
Epidemiology of hepatitis E virus infection in animals in Africa: a systematic review and meta-analysis protocol. ( 31109366 )
2019
15
New pieces in the transmission cycle of the hepatitis E virus in South America: first viral detection in wild boars from Argentina. ( 31111932 )
2019
16
Hepatic immune response against Hepatitis E virus genotype 1 infection among animal models. ( 31063539 )
2019
17
Prevalence of anti-Hepatitis E virus immunoglobulin G in HIV-infected individuals over three decades. ( 31063824 )
2019
18
PREVALENCE OF HEPATITIS E VIRUS INFECTION IN MULTIPLE TRANSFUSED BRAZILIAN PATIENTS WITH THALASSEMIA AND SICKLE CELL DISEASE. ( 31066064 )
2019
19
Natural viral co-infections in pig herds affect hepatitis E virus (HEV) infection dynamics and increase the risk of contaminated livers at slaughter. ( 31067014 )
2019
20
Convalescent Plasma Therapy for Persistent Hepatitis E Virus Infection. ( 31075322 )
2019
21
Efficacy and safety of ribavirin therapy for chronic hepatitis E after kidney transplantation: A report of two cases. ( 31077507 )
2019
22
First detection of hepatitis E virus genotype 3 as a common infectious agent in patients with chronic liver damage in Mexico. ( 31080055 )
2019
23
Screening, diagnosis and risks associated with Hepatitis E virus infection. ( 31082277 )
2019
24
Combination therapy of sofosbuvir and ribavirin fails to clear chronic hepatitis E infection in a multivisceral transplanted patient. ( 31027993 )
2019
25
First detection of Hepatitis E virus (Orthohepevirus C) in wild brown rats (Rattus norvegicus) from Great Britain. ( 31033238 )
2019
26
Seroprevalence and risk factors of hepatitis E among women of childbearing age in the Xieng Khouang province (Lao People's Democratic Republic), a cross-sectional survey. ( 31034060 )
2019
27
Serological and molecular retrospective analysis of hepatitis E suspected cases from the Eastern Brazilian Amazon 1993-2014. ( 31038622 )
2019
28
Meta-transcriptomic analysis reveals a new subtype of genotype 3 avian hepatitis E virus in chicken flocks with high mortality in Guangdong, China. ( 31060564 )
2019
29
New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle. ( 31000788 )
2019
30
Study of hepatitis E virus ORF2 antigen kinetics in human-liver chimeric mice and its impact on HEV diagnosis. ( 31001628 )
2019
31
Screening of novel drugs for inhibiting hepatitis E virus replication. ( 31004661 )
2019
32
Seroprevalence of Hepatitis E Virus Infection in Pigs from Southern Bulgaria. ( 31017536 )
2019
33
First Crystal Structure of a Non-Structural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein. ( 31019049 )
2019
34
Long-term Antibody Persistence After Hepatitis E Virus Infection and Vaccination in Dongtai, China. ( 31024978 )
2019
35
Changing clinical and molecular characteristics of hepatitis E virus infection in Mie Prefecture, Japan: disappearance of indigenous subtype 3e strains. ( 31026368 )
2019
36
Quantification and genetic diversity of Hepatitis E virus in wild boar (Sus scrofa) hunted for domestic consumption in Central Italy. ( 31027773 )
2019
37
Hepatitis E: an underestimated emerging threat. ( 30984394 )
2019
38
Brain Infection by Hepatitis E Virus Probably via Damage of the Blood-Brain Barrier Due to Alterations of Tight Junction Proteins. ( 30949453 )
2019
39
Survey for Hepatitis E virus infection in non-human primates in zoos in Spain. ( 30959551 )
2019
40
Computational identification of Hepatitis-E virus encoded microRNAs and their targets in human. ( 30919453 )
2019
41
Prevalence of Active Hepatitis E Virus Infection and Efficacy of Ribavirin Treatment in Renal Allograft Recipients. ( 30929308 )
2019
42
Prevalence of hepatitis E virus infection among people and swine in mainland China: A systematic review and meta-analysis. ( 30884147 )
2019
43
Antiviral candidates for treating hepatitis E virus infection. ( 30885901 )
2019
44
Genetic diversity of hepatitis E virus (HEV) strains derived from humans, swine and wild boars in Croatia from 2010 to 2017. ( 30890143 )
2019
45
Chicken organic anion transporting polypeptide 1A2, a novel avian hepatitis E virus (HEV) ORF2-interacting protein, is involved in avian HEV infection. ( 30894478 )
2019
46
Acute Hepatitis E is an Underreported Cause of Severe Acute Liver Injury. ( 30902228 )
2019
47
Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study. ( 30903372 )
2019
48
HEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and epidemiological investigations. ( 30862334 )
2019
49
Epidemiology and genotype 3 subtype dynamics of hepatitis E virus in Belgium, 2010 to 2017. ( 30862337 )
2019
50
Hepatitis E virus in blood donors in England, 2016 to 2017: from selective to universal screening. ( 30862338 )
2019

Variations for Hepatitis E

Expression for Hepatitis E

Search GEO for disease gene expression data for Hepatitis E.

Pathways for Hepatitis E

Pathways related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1 12.22 CD40LG IFNG TLR3 TNF
2 11.89 IFNG TLR3 TNF
3
Show member pathways
11.79 ALB F2 IFNG TNF
4
Show member pathways
11.75 IFNG TLR3 TNF
5
Show member pathways
11.71 F2 IFNG TNF
6
Show member pathways
11.56 ALB AMBP HPX
7
Show member pathways
11.38 CD40LG IFNG TNF
8
Show member pathways
11.23 CD40LG IFNG TNF
9
Show member pathways
11.16 IFNG TLR3 TNF VPS4A
10 10.88 F2 IFNG
11 10.82 CD40LG IFNG TNF

GO Terms for Hepatitis E

Cellular components related to Hepatitis E according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 ALB AMBP CD40LG F2 FGB HPX
2 extracellular exosome GO:0070062 9.76 ALB AMBP F2 FGB GPT HPX
3 cell surface GO:0009986 9.72 AMBP CD40LG FGB TLR3 TNF
4 external side of plasma membrane GO:0009897 9.67 CD40LG F2 FGB TNF
5 blood microparticle GO:0072562 9.35 ALB AMBP F2 FGB HPX
6 extracellular space GO:0005615 9.32 ALB AMBP CD40LG F2 FGB GPT

Biological processes related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.91 CD40LG F2 IFNG TNF
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.77 CD40LG TLR3 TNF
3 response to virus GO:0009615 9.7 IFNG TLR3 TNF
4 platelet activation GO:0030168 9.69 CD40LG F2 FGB
5 positive regulation of protein complex assembly GO:0031334 9.62 IFNG TNF
6 fibrinolysis GO:0042730 9.61 F2 FGB
7 positive regulation of osteoclast differentiation GO:0045672 9.59 IFNG TNF
8 viral budding via host ESCRT complex GO:0039702 9.58 TSG101 VPS4A
9 positive regulation of chemokine production GO:0032722 9.58 TLR3 TNF
10 microglial cell activation GO:0001774 9.57 TLR3 TNF
11 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.56 IFNG TNF
12 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 9.55 TSG101 VPS4A
13 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.54 FGB TNF
14 extrinsic apoptotic signaling pathway GO:0097191 9.54 IFNG TLR3 TNF
15 positive regulation of viral release from host cell GO:1902188 9.49 TSG101 VPS4A
16 positive regulation of chemokine biosynthetic process GO:0045080 9.48 TLR3 TNF
17 necroptotic signaling pathway GO:0097527 9.46 TLR3 TNF
18 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.43 HPX TNF
19 regulation of immunoglobulin secretion GO:0051023 9.4 CD40LG TNF
20 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IFNG TNF
21 positive regulation of viral budding via host ESCRT complex GO:1903774 9.26 TSG101 VPS4A
22 positive regulation of vitamin D biosynthetic process GO:0060557 9.16 IFNG TNF
23 positive regulation of interleukin-12 production GO:0032735 9.13 CD40LG IFNG TLR3
24 positive regulation of exosomal secretion GO:1903543 8.8 IFNG TSG101 VPS4A

Sources for Hepatitis E

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....