MCID: HPT007
MIFTS: 53

Hepatitis E

Categories: Rare diseases, Infectious diseases, Genetic diseases, Gastrointestinal diseases, Liver diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Hepatitis E

MalaCards integrated aliases for Hepatitis E:

Name: Hepatitis E 12 76 53 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4411
MeSH 44 D016751
SNOMED-CT 68 7111000119109
UMLS 73 C0085293

Summaries for Hepatitis E

Disease Ontology : 12 A viral infectious disease that results in inflammation located in liver, has material basis in Hepatitis E virus, which is transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom fatigue, has symptom loss of appetite, has symptom nausea, has symptom vomiting, has symptom abdominal pain, has symptom clay-colored bowel movements, has symptom dark urine, has symptom joint pain, and has symptom jaundice.

MalaCards based summary : Hepatitis E is related to hepatitis and acute liver failure, and has symptoms including fever, fatigue and loss of appetite. An important gene associated with Hepatitis E is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Influenza A and RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways. The drugs Ribavirin and Aluminum hydroxide have been mentioned in the context of this disorder. Affiliated tissues include liver, liver and kidney, and related phenotype is digestive/alimentary.

Wikipedia : 76 Hepatitis E is a viral hepatitis (liver inflammation) caused by infection with a virus called hepatitis... more...

Related Diseases for Hepatitis E

Diseases in the Hepatitis family:

Hepatitis C Virus Autoimmune Hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Hepatitis E via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 216)
# Related Disease Score Top Affiliating Genes
1 hepatitis 31.4 DDX58 F2 GPT TNF
2 acute liver failure 30.8 ALB F2 GPT
3 autoimmune hepatitis 30.0 CD40LG F2 GPT
4 guillain-barre syndrome 30.0 ALB CD40LG TNF
5 cholecystitis 29.9 ALB F2 GPT
6 hepatitis d 29.8 CD40LG F2 GPT
7 liver disease 29.7 ALB F2 GPT TNF
8 alcoholic hepatitis 29.6 ALB F2 GPT TNF
9 leptospirosis 29.6 CD40LG F2 TNF
10 viral hepatitis 29.5 ALB CD40LG F2 GPT TNF
11 hepatitis b 29.5 ALB F2 GPT IFNG TNF
12 hepatitis a 29.4 ALB CD40LG F2 GPT TNF
13 chikungunya 29.4 CD40LG DDX58 TNF
14 hepatitis c 28.9 DDX58 GPT IFNG TLR3 TNF
15 schistosomiasis 28.5 ALB CD40LG F2 IFNG TNF
16 hepatoportal sclerosis 10.8 F2 GPT
17 antipyrine metabolism 10.8 ALB F2
18 non-a-e hepatitis 10.8 ALB F2
19 variola major 10.7 IFNG TLR3
20 abdominal tuberculosis 10.7 ALB F2
21 gastrointestinal tuberculosis 10.7 ALB IFNG
22 marburg hemorrhagic fever 10.7 F2 TNF
23 staphylococcal toxic shock syndrome 10.7 IFNG TNF
24 autoimmune myocarditis 10.7 IFNG TNF
25 adult dermatomyositis 10.6 GPT TNF
26 trichosporonosis 10.6 IFNG TNF
27 chronic beryllium disease 10.6 IFNG TNF
28 chronic graft versus host disease 10.6 ALB IFNG
29 livedoid vasculopathy 10.6 CD40LG F2
30 colorado tick fever 10.6 ALB CD40LG
31 cork-handlers' disease 10.6 ALB CD40LG
32 mucocutaneous leishmaniasis 10.6 TLR3 TNF
33 clonorchiasis 10.6 IFNG TNF
34 african tick-bite fever 10.5 CD40LG IFNG
35 burns 10.5 ALB TNF
36 cat-scratch disease 10.5 CD40LG IFNG
37 plasmodium malariae malaria 10.5 ALB CD40LG
38 crohn's colitis 10.5 IFNG TNF
39 kwashiorkor 10.5 ALB F2 GPT
40 hepatic tuberculosis 10.5 ALB F2 GPT
41 hepatic coma 10.5 ALB F2 GPT
42 sporotrichosis 10.5 CD40LG IFNG
43 choledocholithiasis 10.5 ALB F2 GPT
44 microscopic colitis 10.5 IFNG TNF
45 analbuminemia 10.5 ALB F2 GPT
46 fascioliasis 10.5 ALB GPT IFNG
47 meconium aspiration syndrome 10.5 IFNG TNF
48 bile duct disease 10.5 ALB F2 GPT
49 hantavirus pulmonary syndrome 10.5 CD40LG F2
50 nonalcoholic steatohepatitis 10.5 F2 GPT TNF

Graphical network of the top 20 diseases related to Hepatitis E:



Diseases related to Hepatitis E

Symptoms & Phenotypes for Hepatitis E

Symptoms:

12
  • fever
  • fatigue
  • loss of appetite
  • nausea
  • vomiting
  • abdominal pain
  • clay-colored bowel movements
  • dark urine
  • joint pain
  • jaundice

MGI Mouse Phenotypes related to Hepatitis E:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.1 ALB DDX58 F2 IFNG TNF VPS4A

Drugs & Therapeutics for Hepatitis E

Drugs for Hepatitis E (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ribavirin Approved Phase 4,Phase 2 36791-04-5 37542
2
Aluminum hydroxide Approved, Investigational Phase 4,Phase 3 21645-51-2
3
Aluminum sulfate Approved Phase 4,Phase 3 10043-01-3
4 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
5 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
6 Antimetabolites Phase 4,Phase 2
7 Antiviral Agents Phase 4,Phase 2,Not Applicable
8
Nicotinamide Approved, Investigational, Nutraceutical Phase 2, Phase 3,Phase 3 98-92-0 936
9
Niacin Approved, Investigational, Nutraceutical Phase 2, Phase 3,Phase 3 59-67-6 938
10
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3 83-88-5 493570
11
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3,Phase 3 59-43-8, 70-16-6 1130
12
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
13 Micronutrients Phase 2, Phase 3
14 Nicotinic Acids Phase 2, Phase 3
15 Trace Elements Phase 2, Phase 3
16 Vitamin B Complex Phase 2, Phase 3
17 Vitamins Phase 2, Phase 3
18 Antioxidants Phase 2, Phase 3
19 Protective Agents Phase 2, Phase 3
20 silymarin Nutraceutical Phase 2, Phase 3
21 Folate Nutraceutical Phase 2, Phase 3
22 Vitamin B3 Nutraceutical Phase 2, Phase 3
23 Milk Thistle Nutraceutical Phase 2, Phase 3
24 Thiamin Nutraceutical Phase 2, Phase 3
25 Vitamin B2 Nutraceutical Phase 2, Phase 3
26 Vitamin B9 Nutraceutical Phase 2, Phase 3
27
Entecavir Approved, Investigational Phase 2,Not Applicable 142217-69-4 153941
28
Peginterferon alfa-2a Approved, Investigational Phase 2 198153-51-4 5360545
29
Sofosbuvir Approved Phase 2 1190307-88-0 45375808
30 Liver Extracts Phase 2,Phase 1
31 interferons Phase 2
32
Basiliximab Approved, Investigational Phase 1 152923-56-3, 179045-86-4
33
Tacrolimus Approved, Investigational Phase 1 104987-11-3 445643 439492
34 Immunosuppressive Agents Phase 1
35
Permethrin Approved, Investigational Not Applicable 52645-53-1 40326
36 Antibodies
37 Immunoglobulins

Interventional clinical trials:

(show all 31)
# Name Status NCT ID Phase Drugs
1 Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®) Unknown status NCT02189603 Phase 4
2 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients ) Completed NCT02964910 Phase 4
3 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli) Completed NCT02417597 Phase 4
4 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine) Completed NCT02584543 Phase 4
5 Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh. Recruiting NCT02759991 Phase 4 Hecolin;Hepa-B
6 A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule) Active, not recruiting NCT03168412 Phase 4
7 Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection. Active, not recruiting NCT02558114 Phase 4 Ribavirin
8 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Withdrawn NCT03365921 Phase 4
9 Clinical Trial of Recombinant Hepatitis E Vaccine Unknown status NCT01014845 Phase 3
10 Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )Vaccine Active, not recruiting NCT01735006 Phase 3
11 Field Trial of Maternal Influenza Immunization in Asia Active, not recruiting NCT01034254 Phase 3
12 Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis Terminated NCT00755950 Phase 2, Phase 3
13 A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus Unknown status NCT01698723 Phase 2 Ribavirin;Placebo
14 Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine Unknown status NCT02710851 Phase 2
15 Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen Completed NCT01204762 Phase 2 pegIFN;pegIFNα-2a;PegIFN lambda;Entecavir
16 HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE) Recruiting NCT03282474 Phase 2 Sofosbuvir
17 A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal. Withdrawn NCT00287469 Phase 2
18 A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy Adults Completed NCT02603055 Phase 1
19 Safety and Tolerance of Immunomodulating Therapy With Donor-specific MSC in Pediatric Living-Donor Liver Transplantation Recruiting NCT02957552 Phase 1
20 Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb) Unknown status NCT02847507
21 The Epidemiology of Hepatitis E Virus Infection in Israel and Potential Risk Factors Unknown status NCT02419625 Not Applicable
22 Epidemiological Study of Hepatitis E Virus in Maintenance Hemodialysis Patients Unknown status NCT02645955
23 Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille. Unknown status NCT02819128 Not Applicable
24 Role of Cytokines in Hepatitis E Virus Infection During Pregnancy Completed NCT01062321
25 Host Responses in Kidney-transplant Recipients With Chronic Hepatitis E Virus Infection Completed NCT01090232 Not Applicable
26 Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy Completed NCT01858519
27 Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110E Completed NCT01813487 Not Applicable HBsAg vaccine with Entecavir
28 Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study Recruiting NCT02809885 Not Applicable
29 Seroprevalence of Hepatitis E in People With an Organ Transplant Recruiting NCT02190253
30 HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for Liver Not yet recruiting NCT03488589
31 Hepatitis E Infection : Emergence Mechanisms in North-Eastern France of Polymorphic Clinical Forms. Not yet recruiting NCT03524014

Search NIH Clinical Center for Hepatitis E

Cochrane evidence based reviews: hepatitis e

Genetic Tests for Hepatitis E

Anatomical Context for Hepatitis E

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatitis E:

19
Liver

MalaCards organs/tissues related to Hepatitis E:

41
Liver, Kidney, Testes, T Cells, B Cells, Thyroid, Lung

Publications for Hepatitis E

Articles related to Hepatitis E:

(show top 50) (show all 806)
# Title Authors Year
1
Treating chronic hepatitis E: when is enough enough? ( 29391359 )
2018
2
Ribavirin in Acute Hepatitis E Infection in Patients with Gynecological Cancer: A Case Series. ( 29951369 )
2018
3
Proposal for a new subtype of the zoonotic genotype 3 Hepatitis E virus: HEV-3l. ( 29452164 )
2018
4
Origin and dispersal of Hepatitis E virus. ( 29410449 )
2018
5
Detection of Astrovirus, Rotavirus C, and Hepatitis E Viral RNA in Adult and Juvenile Farmed Mink (<i>Neovison vison</i>). ( 29974054 )
2018
6
First detection and molecular characterization of hepatitis E virus in water from wastewater treatment plants in Portugal. ( 29936796 )
2018
7
Hepatitis E virus in neurological disorders: a case of Parsonage-Turner syndrome. ( 29685043 )
2018
8
Adult-Onset Still Disease and Macrophage Activation Syndrome Following Chikungunya and Hepatitis E Coinfection. ( 29485548 )
2018
9
The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia. ( 29404765 )
2018
10
Comparison of hepatitis E virus seroprevalence between HBsAg-positive population and healthy controls in Shandong province, China. ( 29433428 )
2018
11
Hepatitis E virus seroprevalence in Polish soldiers serving in harsh environmental conditions. ( 29939391 )
2018
12
Transfusion-Transmitted Hepatitis E: NAT Screening of Blood Donations and Infectious Dose. ( 29450199 )
2018
13
Toward Systematic Screening for Persistent Hepatitis E Virus Infections in Transplant Patients. ( 29953421 )
2018
14
Hepatitis E - A new era in understanding. ( 29936817 )
2018
15
Detection and quantification of hepatitis E virus in the absence of IgG and IgM anti-HEV in HIV positive patients. ( 29920871 )
2018
16
Prevalence of hepatitis E virus RNA and antibodies in a cohort of kidney transplant recipients in Central Brazil. ( 29408465 )
2018
17
Substitution of amino acid residue V1213 in the helicase domain of the genotype 3 hepatitis E virus reduces virus replication. ( 29422085 )
2018
18
Prevalence of hepatitis E in liver transplant recipients in Greece. ( 29974836 )
2018
19
Diversity of hepatitis E virus genotype 3. ( 29939461 )
2018
20
Acute hepatitis E in India appears to be caused exclusively by genotype 1 hepatitis E virus. ( 29399748 )
2018
21
Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4. ( 29435117 )
2018
22
Autochthonous acute hepatitis E mimicking CMV infection. ( 29903610 )
2018
23
Seroprevalence and risk factors of recent infection with hepatitis E virus during an acute outbreak in an urban setting in Chad, 2017. ( 29940939 )
2018
24
Detection and genomic characterization of new avian-like hepatitis E virus in a sparrow in the United States. ( 29971485 )
2018
25
Activities of Thrombin and Factor Xa Are Essential for Replication of Hepatitis E Virus and Are Possibly Implicated in ORF1 Polyprotein Processing. ( 29321328 )
2018
26
Autochthonous acute hepatitis E: treatment with sofosbuvir and ribavirin. ( 29946850 )
2018
27
Host-Virus Protein Interaction Network Reveals the Involvement of Multiple Host Processes in the Life Cycle of Hepatitis E Virus. ( 29404423 )
2018
28
Interferona89I>4 gene polymorphisms, circulating interferon I>3, and clinical variables in hemodialysis patients exposed to hepatitis E virus. ( 29968695 )
2018
29
Aujeszky's Disease and Hepatitis E Viruses Transmission between Domestic Pigs and Wild Boars in Corsica: Evaluating the Importance of Wild/Domestic Interactions and the Efficacy of Management Measures. ( 29417054 )
2018
30
Elucidating the differences in pathogenicity between hepatitis E virus genotypes: The quest continues. ( 29404519 )
2018
31
A fully automated system using transcription-mediated amplification for the molecular diagnosis of hepatitis E virus in human blood and faeces. ( 29957544 )
2018
32
Benign recurrent intrahepatic cholestasis (BRIC)-like episode associated with ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection. ( 29191380 )
2018
33
Hepatitis E outbreak at a nursing home for aged people in Hokkaido, Japan, between February and March 2016. ( 29414183 )
2018
34
Chronic Hepatitis E in a Renal Transplant Recipient: The First Report of Genotype 4 Hepatitis E Virus Caused Chronic InfectionA in Organ Recipient. ( 29432746 )
2018
35
Acute Motor Axonal Neuropathy in Association with Hepatitis E. ( 29479336 )
2018
36
Cholemic Nephrosis from Acute Hepatitis E Virus Infection: A Forgotten Entity? ( 29962682 )
2018
37
Acute hepatitis E in French patients and neurological manifestations. ( 29966614 )
2018
38
Hepatitis E virus infection of slaughtered healthy pigs in Brazil. ( 29441690 )
2018
39
Hepatitis E virus replication and interferon responses in human placental cells. ( 29404525 )
2018
40
Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review. ( 29357816 )
2018
41
First Report of the Presence of Hepatitis E Virus in Scottish-Harvested Shellfish Purchased at Retail Level. ( 29442296 )
2018
42
Hepatitis E virus-associated cryoglobulinemia in solid-organ-transplant recipients. ( 29845733 )
2018
43
Evaluation of antiviral efficacy of Chinese traditional medicine Babao Dan in rabbits infected with hepatitis E virus. ( 29923821 )
2018
44
Phylogenetic analysis of Hepatitis E virus strains isolated from slaughter-age pigs in Colombia. ( 28063923 )
2017
45
Hepatitis E virus detected from Chinese laboratory ferrets and farmed mink. ( 28941157 )
2017
46
Hepatitis E virus infection as a promoting factor for hepatocellular carcinoma in Cameroon: Preliminary Observations. ( 28847760 )
2017
47
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population. ( 28606414 )
2017
48
Hepatitis E. ( 28910479 )
2017
49
High frequency of hepatitis E virus infection in swine from South Brazil and close similarity to human HEV isolates. ( 28089613 )
2017
50
Parsonage-Turner syndrome due to autochthonous acute genotype 3f hepatitis E virus infection in a nonimmunocompromised 55-year-old patient. ( 28439773 )
2017

Variations for Hepatitis E

Expression for Hepatitis E

Search GEO for disease gene expression data for Hepatitis E.

Pathways for Hepatitis E

Pathways related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.53 DDX58 IFNG TLR3 TNF
2
Show member pathways
12.42 DDX58 IFNG TLR3 TNF
3
Show member pathways
12.23 CD40LG TLR3 TNF
4
Show member pathways
11.98 IFNG TLR3 TNF
5 11.89 IFNG TLR3 TNF
6
Show member pathways
11.89 ALB F2 IFNG TNF
7 11.73 DDX58 TLR3 TNF
8 11.56 CD40LG DDX58 TNF
9 11.54 CD40LG DDX58 IFNG TLR3 TNF
10
Show member pathways
11.49 IFNG TLR3 TNF VPS4A
11
Show member pathways
11.43 CD40LG IFNG TNF
12
Show member pathways
11.3 CD40LG IFNG TNF
13 11.02 CD40LG IFNG TNF
14 10.88 F2 IFNG

GO Terms for Hepatitis E

Cellular components related to Hepatitis E according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ALB CD40LG F2 FGB GPT IFNG
2 external side of plasma membrane GO:0009897 8.92 CD40LG F2 FGB TNF

Biological processes related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.91 CD40LG F2 IFNG TNF
2 positive regulation of gene expression GO:0010628 9.87 DDX58 IFNG TLR3 TNF
3 positive regulation of protein phosphorylation GO:0001934 9.79 F2 IFNG TNF
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.76 CD40LG TLR3 TNF
5 platelet activation GO:0030168 9.71 CD40LG F2 FGB
6 positive regulation of interferon-beta production GO:0032728 9.62 DDX58 TLR3
7 positive regulation of protein complex assembly GO:0031334 9.61 IFNG TNF
8 positive regulation of osteoclast differentiation GO:0045672 9.6 IFNG TNF
9 fibrinolysis GO:0042730 9.59 F2 FGB
10 positive regulation of chemokine production GO:0032722 9.58 TLR3 TNF
11 positive regulation of interleukin-6 production GO:0032755 9.58 DDX58 TLR3 TNF
12 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.56 IFNG TNF
13 cellular response to exogenous dsRNA GO:0071360 9.55 DDX58 TLR3
14 extrinsic apoptotic signaling pathway GO:0097191 9.54 IFNG TLR3 TNF
15 positive regulation of exosomal secretion GO:1903543 9.52 IFNG VPS4A
16 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.51 FGB TNF
17 positive regulation of chemokine biosynthetic process GO:0045080 9.49 TLR3 TNF
18 necroptotic signaling pathway GO:0097527 9.48 TLR3 TNF
19 detection of virus GO:0009597 9.46 DDX58 TLR3
20 regulation of immunoglobulin secretion GO:0051023 9.43 CD40LG TNF
21 positive regulation of interleukin-8 production GO:0032757 9.33 DDX58 TLR3 TNF
22 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IFNG TNF
23 positive regulation of vitamin D biosynthetic process GO:0060557 9.26 IFNG TNF
24 positive regulation of interleukin-12 production GO:0032735 9.13 CD40LG IFNG TLR3
25 response to virus GO:0009615 8.92 DDX58 IFNG TLR3 TNF

Sources for Hepatitis E

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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