MCID: HPT066
MIFTS: 20

Hepatoportal Sclerosis

Categories: Liver diseases, Rare diseases

Aliases & Classifications for Hepatoportal Sclerosis

MalaCards integrated aliases for Hepatoportal Sclerosis:

Name: Hepatoportal Sclerosis 59
Obliterative Portal Venopathy 59

Characteristics:

Orphanet epidemiological data:

59
hepatoportal sclerosis
Age of onset: All ages;

Classifications:

Orphanet: 59  
Rare hepatic diseases


External Ids:

Orphanet 59 ORPHA64743
ICD10 via Orphanet 34 K74.1

Summaries for Hepatoportal Sclerosis

MalaCards based summary : Hepatoportal Sclerosis, also known as obliterative portal venopathy, is related to portal hypertension and hepatitis. An important gene associated with Hepatoportal Sclerosis is ACE (Angiotensin I Converting Enzyme). Affiliated tissues include liver and endothelial.

Related Diseases for Hepatoportal Sclerosis

Diseases related to Hepatoportal Sclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 portal hypertension 30.1 F2 GPT
2 hepatitis 28.8 F2 GPT
3 aortic valve insufficiency 10.1 ACE ELN
4 infantile liver failure syndrome 1 10.1
5 aortic valve disease 1 10.0 ACE ELN
6 nodular regenerative hyperplasia 10.0
7 adams-oliver syndrome 1 10.0
8 oliver syndrome 10.0
9 adams-oliver syndrome 10.0
10 aortic valve disease 2 9.9 ACE ELN
11 kwashiorkor 9.9 F2 GPT
12 hepatic tuberculosis 9.9 F2 GPT
13 hepatic coma 9.9 F2 GPT
14 nonalcoholic steatohepatitis 9.9 F2 GPT
15 hepatitis d 9.9 F2 GPT
16 ischemic heart disease 9.9 ACE F2
17 arteriosclerosis 9.9 ACE ELN
18 adenoma 9.9
19 banti's syndrome 9.9
20 myasthenia gravis congenital 9.9
21 endotheliitis 9.9
22 thrombophilia due to thrombin defect 9.9
23 myasthenia gravis 9.9
24 crohn's disease 9.9
25 thrombosis 9.9
26 hemorrhagic fever 9.9 F2 GPT
27 choledocholithiasis 9.9 F2 GPT
28 hepatorenal syndrome 9.9 ACE F2
29 analbuminemia 9.9 F2 GPT
30 arteritic anterior ischemic optic neuropathy 9.9 ACE F2
31 hepatitis e 9.8 F2 GPT
32 acute liver failure 9.8 F2 GPT
33 ischemic optic neuropathy 9.8 ACE F2
34 bile duct disease 9.8 F2 GPT
35 intermittent claudication 9.8 ACE F2
36 hepatitis a 9.8 F2 GPT
37 nonarteritic anterior ischemic optic neuropathy 9.8 ACE F2
38 heart conduction disease 9.8 ACE F2
39 cholecystitis 9.8 F2 GPT
40 bilirubin metabolic disorder 9.8 F2 GPT
41 obstructive jaundice 9.8 F2 GPT
42 pulmonary edema 9.8 ACE F2
43 connective tissue disease 9.8 ACE ELN
44 hepatic encephalopathy 9.8 F2 GPT
45 alcoholic hepatitis 9.8 F2 GPT
46 migraine with aura 9.8 ACE F2
47 wilson disease 9.7 F2 GPT
48 cholangitis 9.7 F2 GPT
49 autoimmune hepatitis 9.7 F2 GPT
50 peripheral vascular disease 9.7 ACE F2

Graphical network of the top 20 diseases related to Hepatoportal Sclerosis:



Diseases related to Hepatoportal Sclerosis

Symptoms & Phenotypes for Hepatoportal Sclerosis

Drugs & Therapeutics for Hepatoportal Sclerosis

Search Clinical Trials , NIH Clinical Center for Hepatoportal Sclerosis

Genetic Tests for Hepatoportal Sclerosis

Anatomical Context for Hepatoportal Sclerosis

MalaCards organs/tissues related to Hepatoportal Sclerosis:

41
Liver, Endothelial

Publications for Hepatoportal Sclerosis

Articles related to Hepatoportal Sclerosis:

(show all 38)
# Title Authors Year
1
Hepatobiliary and Pancreatic: Obliterative portal venopathy found in Castleman disease variant of POEMS syndrome. ( 29691905 )
2018
2
Mutations in the novel gene FOPV are associated with familial autosomal dominant and non-familial obliterative portal venopathy. ( 28792652 )
2017
3
A Hepatoportal sclerosis related to the use of herbals and nutritional supplements. Causality or coincidence? ( 27740529 )
2016
4
Progression of Hepatic Adenoma to Carcinoma in the Setting of Hepatoportal Sclerosis in HIV Patient: Case Report and Review of the Literature. ( 27812395 )
2016
5
Mercaptopurine-induced hepatoportal sclerosis in a patient with Crohn's disease. ( 22841133 )
2013
6
Hepatoportal sclerosis (obliterative portal venopathy) and nodular regenerative hyperplasia in a patient with myasthenia gravis: A case report and review of the published work. ( 23675894 )
2013
7
Hepatoportal sclerosis in childhood: descriptive analysis of 12 patients. ( 24133357 )
2013
8
Liver failure and the need for transplantation in 6 patients with hepatoportal sclerosis. ( 23769069 )
2013
9
Obliterative portal venopathy: a clinical and histopathological review. ( 23812828 )
2013
10
Oxaliplatin-induced hepatoportal sclerosis, portal hypertension, and variceal bleeding successfully treated with transjugular intrahepatic portosystemic shunt. ( 22537609 )
2012
11
Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: possible link to serum anti-endothelial cell antibodies. ( 22288597 )
2012
12
Hepatoportal sclerosis: CT and MRI appearance with histopathologic correlation. ( 22268180 )
2012
13
Hepatoportal sclerosis clinical different evolutionary stages: presentation of 3 cases and literature review. ( 22372805 )
2012
14
The involvement of nitric oxide in the physiopathology of hepatoportal sclerosis. ( 22820432 )
2012
15
Hepatoportal sclerosis in childhood: some presenting with cholestatic features (a re-evaluation of 12 children). ( 22150463 )
2012
16
Hepatoportal sclerosis and extrahepatic portal venous obstruction associated with anti-phospholipid antibody syndrome in child. ( 20675717 )
2011
17
The development of hepatoportal sclerosis and portal hypertension due to didanosine use in HIV. ( 21057809 )
2011
18
Elevated levels of circulating angiotensin converting enzyme in patients with hepatoportal sclerosis. ( 21290180 )
2011
19
Obliterative portal venopathy: portal hypertension is not always present at diagnosis. ( 21087805 )
2011
20
Variceal bleeding in an adolescent with HIV diagnosed with hepatoportal sclerosis and nodular regenerative hyperplasia. ( 19841596 )
2010
21
Acquired protein S deficiency leads to obliterative portal venopathy and to compensatory nodular regenerative hyperplasia in HIV-infected patients. ( 19512859 )
2009
22
Response to Schiano et al. Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV. ( 18341510 )
2008
23
Hepatoportal sclerosis: a cause of portal hypertension to bear in mind. ( 18279649 )
2008
24
Liver failure and the need for transplantation in three patients with hepatoportal sclerosis. ( 19100429 )
2008
25
Liver failure and need for liver transplantation in patients with advanced hepatoportal sclerosis. ( 17414109 )
2007
26
Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV. ( 17640321 )
2007
27
Clinical features, serum interleukin-6, and interferon-gamma levels of 34 turkish patients with hepatoportal sclerosis. ( 17404864 )
2007
28
Liver transplantation in precirrhotic biliary tract disease: Portal hypertension is frequently associated with nodular regenerative hyperplasia and obliterative portal venopathy. ( 17063088 )
2006
29
Association of Adams-Oliver syndrome and hepatoportal sclerosis: an additional case. ( 16532468 )
2006
30
Adams-Oliver syndrome and hepatoportal sclerosis: occasional association or common mechanism? ( 15832360 )
2005
31
Hepatoportal sclerosis in a child. ( 15316776 )
2004
32
Hepatoportal sclerosis. ( 8578318 )
1995
33
Hepatoportal sclerosis demonstrated by abdominal ultrasonography. ( 1658085 )
1991
34
Hepatoportal sclerosis in childhood. ( 2421592 )
1986
35
Hepatoportal sclerosis in childhood: a mimic of extrahepatic portal vein obstruction. ( 7252729 )
1981
36
Nodular regenerative hyperplasia of the liver in hematologic disorders: a possible response to obliterative portal venopathy. A morphometric study of nine cases with an hypothesis on the pathogenesis. ( 7432153 )
1980
37
Hepatoportal sclerosis--its relationship to intrahepatic portal venous thrombosis. ( 429020 )
1979
38
Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis). ( 5833586 )
1965

Variations for Hepatoportal Sclerosis

Expression for Hepatoportal Sclerosis

Search GEO for disease gene expression data for Hepatoportal Sclerosis.

Pathways for Hepatoportal Sclerosis

GO Terms for Hepatoportal Sclerosis

Sources for Hepatoportal Sclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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