MCID: HRP006
MIFTS: 65

Herpes Simplex

Categories: Fetal diseases, Infectious diseases, Oral diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Herpes Simplex

MalaCards integrated aliases for Herpes Simplex:

Name: Herpes Simplex 12 54 42 43 15
Herpesvirus Hominis Disease 12
Herpes Simplex Infections 71
Herpes Simplex Disease 74

Classifications:



External Ids:

Disease Ontology 12 DOID:8566
ICD9CM 34 054
MeSH 43 D006561
SNOMED-CT 67 88594005
ICD10 32 B00 B00.9
UMLS 71 C0019348

Summaries for Herpes Simplex

MedlinePlus : 42 Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted disease (STD). It affects the genitals, buttocks or anal area. Other herpes infections can affect the eyes, skin, or other parts of the body. The virus can be dangerous in newborn babies or in people with weak immune systems. There are two types of HSV: HSV type 1 most commonly causes cold sores. It can also cause genital herpes. HSV type 2 is the usual cause of genital herpes, but it also can infect the mouth. HSV spreads through direct contact. Some people have no symptoms. Others get sores near the area where the virus has entered the body. They turn into blisters, become itchy and painful, and then heal. Most people have outbreaks several times a year. Over time, you get them less often. Medicines to help your body fight the virus can help lessen symptoms and decrease outbreaks.

MalaCards based summary : Herpes Simplex, also known as herpesvirus hominis disease, is related to herpes simplex encephalitis and genital herpes, and has symptoms including fever, pruritus and halitosis. An important gene associated with Herpes Simplex is NECTIN1 (Nectin Cell Adhesion Molecule 1), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include mouth, face and genitalia, and related phenotypes are Decreased viability and Decreased viability

Disease Ontology : 12 A viral infectious disease that results in formation of lesions, located in mouth, located in face, located in genitalia, or located in hands, has material basis in Human herpesvirus 1 or has material basis in Human herpesvirus 2, which are transmitted by direct contact with an active lesion or body fluid of an infected person.

Wikipedia : 74 Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names Human... more...

Related Diseases for Herpes Simplex

Diseases in the Herpes Simplex family:

Congenital Herpes Simplex

Diseases related to Herpes Simplex via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1198, show less)
# Related Disease Score Top Affiliating Genes
1 herpes simplex encephalitis 35.1 UNC93B1 TRAF3 TLR3 TICAM1 TBK1 IRF3
2 genital herpes 34.4 TNFRSF14 NECTIN1 IFI16
3 herpetic whitlow 33.5 TNFRSF14 NECTIN1
4 acute retinal necrosis syndrome 33.2 TNFRSF14 NECTIN1
5 encephalitis 32.7 UNC93B1 TRAF3 TLR3 TICAM1 IRF3 DDX58
6 measles 31.6 TLR3 IRF3 EIF2AK2 DDX58
7 viral infectious disease 31.4 TLR3 TBK1 IRF3 EIF2AK2 DDX58
8 hepatitis 31.2 TICAM1 TBK1 IRF3 EIF2AK2 DDX58
9 kaposi sarcoma 31.2 TLR3 TBK1 IRF3 IFI16
10 newcastle disease 31.1 TLR3 IRF3 EIF2AK2 DDX58
11 rabies 31.0 TLR3 PML IRF3 DDX58
12 hepatitis c 30.7 TLR3 TBK1 IRF3 EIF2AK2 DDX58
13 west nile virus 30.4 TLR3 IRF3 DDX58
14 influenza 30.4 TRAF3 TLR3 PML IRF3 EIF2AK2 DDX58
15 congenital herpes simplex 12.8
16 herpes simplex virus keratitis 12.8
17 eczema herpeticum 12.6
18 encephalopathy, acute, infection-induced 2 12.5
19 encephalopathy, acute, infection-induced 1 12.5
20 encephalopathy, acute, infection-induced 8 12.3
21 encephalopathy, acute, infection-induced 5 12.1
22 encephalopathy, acute, infection-induced 7 12.1
23 encephalopathy, acute, infection-induced 6 12.1
24 neonatal herpes 12.0
25 erythema multiforme 11.9
26 mollaret meningitis 11.8
27 cytomegalovirus infection 11.7
28 proctitis 11.7
29 aphthous stomatitis 11.7
30 viral pneumonia 11.7
31 cytomegalic inclusion disease 11.7
32 immunodeficiency 31a 11.6
33 herpetic gastritis 11.6
34 hyper-ige recurrent infection syndrome 2, autosomal recessive 11.3
35 hydrocephalus, endocardial fibroelastosis, and cataracts 11.3
36 caspase 8 deficiency 11.3
37 immunodeficiency 62 11.3
38 salivary gland disease 11.3
39 pseudomembranous conjunctivitis 11.3
40 congenital intrauterine infection-like syndrome 11.3
41 pudendal neuralgia 11.3
42 recessive dystrophic epidermolysis bullosa-generalized other 11.3
43 torch syndrome 11.3
44 neurological consequences of cytomegalovirus infection 11.3
45 keratitis, hereditary 11.3
46 chickenpox 11.1
47 stromal keratitis 11.0
48 vaccinia 10.9
49 meningitis 10.9
50 viral encephalitis 10.8
51 stomatitis 10.8
52 yemenite deaf-blind hypopigmentation syndrome 10.8
53 neuroretinitis 10.8
54 herpes zoster 10.8
55 meningoencephalitis 10.8
56 retinitis 10.8
57 glioma 10.8
58 glial tumor 10.8
59 human immunodeficiency virus type 1 10.8
60 eye disease 10.8
61 esophagitis 10.8
62 syphilis 10.8
63 cervical cancer 10.8
64 uveitis 10.7
65 immune deficiency disease 10.7
66 glioblastoma multiforme 10.7
67 chlamydia 10.7
68 neuroblastoma 10.7
69 suppressor of tumorigenicity 3 10.7
70 severe combined immunodeficiency 10.7
71 acquired immunodeficiency syndrome 10.7
72 acute liver failure 10.7
73 bell's palsy 10.7
74 facial paralysis 10.7
75 dermatitis 10.7
76 myelitis 10.7
77 allergic hypersensitivity disease 10.6
78 aseptic meningitis 10.6
79 exanthem 10.6
80 corneal disease 10.6
81 pneumonia 10.6
82 ocular motor apraxia 10.6
83 conjunctivitis 10.6
84 iridocyclitis 10.6
85 47,xyy 10.6
86 polykaryocytosis inducer 10.6
87 malignant glioma 10.6
88 keratoconjunctivitis 10.6
89 rubella 10.6
90 iritis 10.6
91 48,xyyy 10.6
92 alzheimer disease 10.6
93 graft-versus-host disease 10.6
94 lymphocytic leukemia 10.6
95 skin disease 10.6
96 vasculitis 10.6
97 pemphigus 10.6
98 cytokine deficiency 10.5
99 blepharitis 10.5
100 thalamic neoplasm 10.5 TLR3 TBK1
101 papilloma 10.5
102 nervous system disease 10.5
103 neutropenia 10.5
104 squamous cell papilloma 10.5
105 encephalopathy 10.5
106 squamous cell carcinoma 10.5
107 central nervous system disease 10.5
108 oral cancer 10.5
109 neuritis 10.5
110 chorioretinitis 10.5
111 ovarian cancer 10.5
112 pemphigus vulgaris, familial 10.5
113 helix syndrome 10.5
114 cervicitis 10.5
115 endotheliitis 10.5
116 idiopathic recurrent and disabling cutaneous herpes 10.5
117 osteogenic sarcoma 10.5
118 leukemia, chronic lymphocytic 10.5
119 human immunodeficiency virus infectious disease 10.5
120 pancreatic cancer 10.5
121 aphasia 10.5
122 amnestic disorder 10.5
123 lymphadenitis 10.5
124 diencephalic neoplasm 10.5 TLR3 TBK1
125 dermatitis, atopic 10.5
126 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.5
127 bacterial vaginosis 10.5
128 dysphagia 10.5
129 immunodeficiency by defective expression of mhc class i 10.5 TAP2 TAP1
130 microphthalmia with limb anomalies 10.5 TLR3 IRF3 EIF2AK2 DDX58
131 bolivian hemorrhagic fever 10.4 IRF3 DDX58
132 autoimmune disease 10.4
133 colorectal cancer 10.4
134 colitis 10.4
135 mucositis 10.4
136 cataract 10.4
137 xeroderma pigmentosum, variant type 10.4
138 mumps 10.4
139 keratopathy 10.4
140 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.4
141 respiratory failure 10.4
142 gliosarcoma 10.4
143 disseminated intravascular coagulation 10.4
144 status epilepticus 10.4
145 vaginitis 10.4
146 kluver-bucy syndrome 10.4
147 seizure disorder 10.4
148 hepatocellular carcinoma 10.4
149 hepatitis a 10.4
150 guillain-barre syndrome 10.4
151 combined t cell and b cell immunodeficiency 10.4
152 neuropathy 10.4
153 rapidly involuting congenital hemangioma 10.4
154 blepharoconjunctivitis 10.4
155 demyelinating disease 10.4
156 corneal ulcer 10.4
157 crohn's disease 10.4
158 retinoblastoma 10.4
159 hemophagocytic lymphohistiocytosis 10.4
160 viral meningitis 10.4
161 hydrocephalus 10.4
162 corneal neovascularization 10.4
163 visual epilepsy 10.4
164 urethritis 10.4
165 cystitis 10.4
166 familial retinoblastoma 10.4
167 poliomyelitis 10.4
168 t-cell leukemia 10.4
169 in situ carcinoma 10.4
170 cervix uteri carcinoma in situ 10.4
171 cervical intraepithelial neoplasia 10.4
172 systemic lupus erythematosus 10.4
173 pheochromocytoma 10.4
174 retinal detachment 10.4
175 oral squamous cell carcinoma 10.4
176 adrenal gland pheochromocytoma 10.4
177 cytomegalovirus retinitis 10.4
178 cholera 10.4
179 bullous pemphigoid 10.4
180 bacterial meningitis 10.4
181 limbic encephalitis 10.4
182 headache 10.4
183 erythroleukemia, familial 10.3
184 ataxia and polyneuropathy, adult-onset 10.3
185 pars planitis 10.3
186 thrombocytopenia 10.3
187 benign mesothelioma 10.3
188 movement disease 10.3
189 acute necrotizing encephalitis 10.3
190 infertility 10.3
191 rare surgical neurologic disease 10.3
192 aicardi-goutieres syndrome 10.3 UNC93B1 TLR3 TBK1 IRF3 IFI16 DDX58
193 hepatitis c virus 10.3
194 vestibular neuronitis 10.3
195 candidiasis 10.3
196 rhabdomyosarcoma 10.3
197 ulcerative colitis 10.3
198 meningitis and encephalitis 10.3
199 noonan syndrome 1 10.3 TRAF3 TBK1 NECTIN1 IRF3 DDX58
200 trigeminal neuralgia 10.3
201 variola major 10.3
202 anogenital venereal wart 10.3
203 diphtheria 10.3
204 viral hepatitis 10.3
205 temporal lobe epilepsy 10.3
206 fibrosarcoma 10.3
207 myocarditis 10.3
208 smallpox 10.3
209 lupus erythematosus 10.3
210 molluscum contagiosum 10.3
211 allergic encephalomyelitis 10.3
212 spinal cord injury 10.3
213 idiopathic bronchiectasis 10.3 TAP2 TAP1
214 burkitt lymphoma 10.3
215 multiple sclerosis 10.3
216 prostate cancer 10.3
217 meningioma, radiation-induced 10.3
218 meningioma, familial 10.3
219 human herpesvirus 8 10.3
220 hydrops, lactic acidosis, and sideroblastic anemia 10.3
221 lymphoma 10.3
222 sensorineural hearing loss 10.3
223 tonsillitis 10.3
224 japanese encephalitis 10.3
225 corneal edema 10.3
226 spinal meningioma 10.3
227 diarrhea 10.3
228 toxic shock syndrome 10.3
229 epilepsy 10.3
230 pharyngitis 10.3
231 adenocarcinoma 10.3
232 secretory meningioma 10.3
233 lymphoplasmacyte-rich meningioma 10.3
234 endophthalmitis 10.3
235 peptic ulcer disease 10.3
236 toxoplasmosis 10.3
237 autoimmune encephalitis 10.3
238 breast cancer 10.3
239 esophageal cancer 10.3
240 myoclonus and ataxia 10.3
241 wiskott-aldrich syndrome 10.3
242 chlamydia pneumonia 10.3
243 bacterial infectious disease 10.3
244 trichomoniasis 10.3
245 encephalomalacia 10.3
246 cervix carcinoma 10.3
247 astrocytoma 10.3
248 brain edema 10.3
249 acute disseminated encephalomyelitis 10.3
250 intracranial hypertension 10.3
251 tuberculous meningitis 10.3
252 erythema multiforme major 10.3
253 thyroid carcinoma 10.3
254 pfeiffer syndrome 10.2
255 ige responsiveness, atopic 10.2
256 medulloblastoma 10.2
257 mesothelioma, malignant 10.2
258 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
259 branchiootic syndrome 1 10.2
260 severe cutaneous adverse reaction 10.2
261 leukemia, acute lymphoblastic 10.2
262 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
263 keratoconus 10.2
264 gastric ulcer 10.2
265 bullous keratopathy 10.2
266 optic neuritis 10.2
267 male infertility 10.2
268 leukemia 10.2
269 acute leukemia 10.2
270 chancroid 10.2
271 duodenal ulcer 10.2
272 hepatitis b 10.2
273 vulvovaginitis 10.2
274 laryngitis 10.2
275 mouth disease 10.2
276 periodontitis 10.2
277 acute graft versus host disease 10.2
278 transverse myelitis 10.2
279 specific language disorder 10.2
280 transient pseudohypoaldosteronism 10.2
281 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 10.2
282 posterior uveal melanoma 10.2 TAP2 TAP1
283 atherosclerosis susceptibility 10.2
284 bladder cancer 10.2
285 thrombophilia due to thrombin defect 10.2
286 autism 10.2
287 lung cancer 10.2
288 lymphoma, hodgkin, classic 10.2
289 incontinentia pigmenti 10.2
290 nasopharyngeal carcinoma 10.2
291 intraocular pressure quantitative trait locus 10.2
292 pachyonychia congenita 3 10.2
293 bacterial sepsis 10.2
294 adult t-cell leukemia 10.2
295 cutaneous t cell lymphoma 10.2
296 suppression amblyopia 10.2
297 amblyopia 10.2
298 retinal vasculitis 10.2
299 keratosis 10.2
300 embryonal carcinoma 10.2
301 purpura 10.2
302 pustulosis of palm and sole 10.2
303 folliculitis 10.2
304 retinal disease 10.2
305 b-cell lymphoma 10.2
306 peritonitis 10.2
307 arthritis 10.2
308 psoriasis 10.2
309 lichen planus 10.2
310 interstitial keratitis 10.2
311 microcephaly 10.2
312 ovarian epithelial cancer 10.2
313 chronic encephalitis 10.2
314 sarcoidosis 1 10.2
315 triiodothyronine receptor auxiliary protein 10.2
316 ataxia-telangiectasia 10.2
317 gaucher disease, type ii 10.2
318 hydrops fetalis, nonimmune 10.2
319 myeloma, multiple 10.2
320 lymphoma, non-hodgkin, familial 10.2
321 chorea, childhood-onset, with psychomotor retardation 10.2
322 laryngotracheitis 10.2
323 tick-borne encephalitis 10.2
324 inflammatory bowel disease 10.2
325 endometritis 10.2
326 pelvic inflammatory disease 10.2
327 asymptomatic neurosyphilis 10.2
328 lymphocytic choriomeningitis 10.2
329 superficial keratitis 10.2
330 telangiectasis 10.2
331 choreatic disease 10.2
332 polyneuropathy 10.2
333 labyrinthitis 10.2
334 impotence 10.2
335 constipation 10.2
336 sensory peripheral neuropathy 10.2
337 orchitis 10.2
338 cerebritis 10.2
339 cellulitis 10.2
340 vulvitis 10.2
341 retrograde amnesia 10.2
342 subacute delirium 10.2
343 yellow fever 10.2
344 muscular dystrophy 10.2
345 hypoglycemia 10.2
346 congenital cytomegalovirus 10.2
347 leukoplakia 10.2
348 neurosyphilis 10.2
349 splenomegaly 10.2
350 chronic pain 10.2
351 obsolete: squamous cell carcinoma of head and neck 10.2
352 renal cell carcinoma, nonpapillary 10.1
353 benign chronic pemphigus 10.1
354 small cell cancer of the lung 10.1
355 down syndrome 10.1
356 thymoma, familial 10.1
357 leukemia, acute myeloid 10.1
358 esophagitis, eosinophilic, 1 10.1
359 major affective disorder 8 10.1
360 major affective disorder 9 10.1
361 dengue virus 10.1
362 hemorrhagic cystitis 10.1
363 pain agnosia 10.1
364 cardiac arrest 10.1
365 common cold 10.1
366 conjunctival folliculosis 10.1
367 adult respiratory distress syndrome 10.1
368 lyme disease 10.1
369 vaginal disease 10.1
370 common variable immunodeficiency 10.1
371 viral labyrinthitis 10.1
372 vulva cancer 10.1
373 pancytopenia 10.1
374 brain cancer 10.1
375 interstitial cystitis 10.1
376 glossitis 10.1
377 papilledema 10.1
378 vascular disease 10.1
379 optic nerve disease 10.1
380 neuroma 10.1
381 agammaglobulinemia 10.1
382 acute kidney failure 10.1
383 neurilemmoma 10.1
384 ischemia 10.1
385 thymoma 10.1
386 bipolar disorder 10.1
387 skin carcinoma 10.1
388 gastritis 10.1
389 pyoderma 10.1
390 macular retinal edema 10.1
391 benign ependymoma 10.1
392 cellular ependymoma 10.1
393 peripheral nervous system disease 10.1
394 paraplegia 10.1
395 lymphopenia 10.1
396 progressive multifocal leukoencephalopathy 10.1
397 connective tissue disease 10.1
398 hepatoblastoma 10.1
399 impetigo 10.1
400 pyoderma gangrenosum 10.1
401 hard palate cancer 10.1
402 hypereosinophilic syndrome 10.1
403 sudden sensorineural hearing loss 10.1
404 sutton disease 2 10.1
405 head injury 10.1
406 postherpetic neuralgia 10.1
407 vulvar intraepithelial neoplasia 10.1
408 neurotrophic keratopathy 10.1
409 infectious encephalitis 10.1
410 argentine hemorrhagic fever 10.1 IRF3 DDX58
411 neurofibromatosis, type ii 10.1
412 hypercarotenemia and vitamin a deficiency, autosomal dominant 10.1
413 glioma susceptibility 1 10.1
414 hair whorl 10.1
415 thyroid carcinoma, familial medullary 10.1
416 melanoma, uveal 10.1
417 meniere disease 10.1
418 neurofibromatosis, type iv, of riccardi 10.1
419 rheumatoid arthritis 10.1
420 schizophrenia 10.1
421 hydrocephalus, congenital, 1 10.1
422 myasthenia gravis 10.1
423 proteasome-associated autoinflammatory syndrome 1 10.1
424 suppression of tumorigenicity 12 10.1
425 lung cancer susceptibility 3 10.1
426 chorioamnionitis 10.1
427 thrombosis 10.1
428 optic papillitis 10.1
429 pre-eclampsia 10.1
430 microphthalmia 10.1
431 open-angle glaucoma 10.1
432 herpangina 10.1
433 hemiplegia 10.1
434 sarcoma 10.1
435 keratomalacia 10.1
436 tetanus 10.1
437 panuveitis 10.1
438 punctate epithelial keratoconjunctivitis 10.1
439 posterior uveitis 10.1
440 leiomyoma 10.1
441 shipyard eye 10.1
442 chronic cervicitis 10.1
443 melanoma 10.1
444 cholecystitis 10.1
445 gastroenteritis 10.1
446 epidermolysis bullosa 10.1
447 contact dermatitis 10.1
448 acute pancreatitis 10.1
449 glomerulonephritis 10.1
450 grade iii astrocytoma 10.1
451 liposarcoma 10.1
452 breast adenocarcinoma 10.1
453 vaginal discharge 10.1
454 craniopharyngioma 10.1
455 thyroid gland medullary carcinoma 10.1
456 spindle cell sarcoma 10.1
457 rhinitis 10.1
458 hydranencephaly 10.1
459 pancreatitis 10.1
460 liver cirrhosis 10.1
461 kidney disease 10.1
462 bronchitis 10.1
463 malignant pleural mesothelioma 10.1
464 neuronitis 10.1
465 myeloid leukemia 10.1
466 lymphangitis 10.1
467 croup 10.1
468 diabetes insipidus 10.1
469 pulmonary embolism 10.1
470 pathologic nystagmus 10.1
471 acanthamoeba keratitis 10.1
472 herpes virus antenatal infection 10.1
473 homologous wasting disease 10.1
474 iridocorneal endothelial syndrome 10.1
475 pemphigus foliaceus 10.1
476 pyogenic granuloma 10.1
477 virus associated hemophagocytic syndrome 10.1
478 cerebral atrophy 10.1
479 myoclonus 10.1
480 paresthesia 10.1
481 infectious epithelial keratitis 10.1
482 hemophagocytic syndrome associated with an infection 10.1
483 fixed drug eruption 10.1
484 lymphedema 10.1
485 atrial standstill 1 10.0
486 huntington disease 10.0
487 thrombocytopenic purpura, autoimmune 10.0
488 mycosis fungoides 10.0
489 subacute sclerosing panencephalitis 10.0
490 lesch-nyhan syndrome 10.0
491 muscular dystrophy, duchenne type 10.0
492 aceruloplasminemia 10.0
493 acute hemorrhagic leukoencephalitis 10.0
494 pulmonary disease, chronic obstructive 10.0
495 malaria 10.0
496 kawasaki disease 10.0
497 aspergillosis 10.0
498 leukemia, acute lymphoblastic 3 10.0
499 cholangiocarcinoma 10.0
500 mucopolysaccharidosis-plus syndrome 10.0
501 la crosse encephalitis 10.0
502 mantle cell lymphoma 10.0
503 autism spectrum disorder 10.0
504 salmonellosis 10.0
505 cerebral artery occlusion 10.0
506 interstitial nephritis 10.0
507 mastitis 10.0
508 pertussis 10.0
509 acute conjunctivitis 10.0
510 ornithosis 10.0
511 choroiditis 10.0
512 fuchs' endothelial dystrophy 10.0
513 detrusor sphincter dyssynergia 10.0
514 bronchopneumonia 10.0
515 pseudobulbar palsy 10.0
516 acoustic neuroma 10.0
517 carotid stenosis 10.0
518 paronychia 10.0
519 oral candidiasis 10.0
520 norwegian scabies 10.0
521 urticaria 10.0
522 pericarditis 10.0
523 rectum cancer 10.0
524 focal epilepsy 10.0
525 relapsing-remitting multiple sclerosis 10.0
526 hairy cell leukemia 10.0
527 gingivitis 10.0
528 oligodendroglioma 10.0
529 plague 10.0
530 pancreatic ductal adenocarcinoma 10.0
531 choriocarcinoma 10.0
532 lactic acidosis 10.0
533 cervical adenocarcinoma 10.0
534 verrucous carcinoma 10.0
535 pancreatic adenocarcinoma 10.0
536 agnosia 10.0
537 radiculopathy 10.0
538 burning mouth syndrome 10.0
539 intrahepatic cholangiocarcinoma 10.0
540 anterograde amnesia 10.0
541 hemolytic anemia 10.0
542 cll/sll 10.0
543 cerebrovascular disease 10.0
544 scabies 10.0
545 lung disease 10.0
546 neuromyelitis optica 10.0
547 cowpox 10.0
548 glaucomatocyclitic crisis 10.0
549 tracheitis 10.0
550 fatty liver disease 10.0
551 ulcerative stomatitis 10.0
552 diabetic neuropathy 10.0
553 refractive error 10.0
554 congenital syphilis 10.0
555 chronic graft versus host disease 10.0
556 cluster headache 10.0
557 congenital varicella syndrome 10.0
558 erythrokeratoderma ''en cocardes'' 10.0
559 granulocytopenia 10.0
560 haemophilus influenzae 10.0
561 herpes zoster ophthalmicus 10.0
562 hypoxia 10.0
563 cerebrofacial arteriovenous metameric syndrome 10.0
564 immune hydrops fetalis 10.0
565 malignant epithelial tumor of ovary 10.0
566 alcohol dependence 9.9
567 amyotrophic lateral sclerosis 1 9.9
568 carpal tunnel syndrome 9.9
569 creutzfeldt-jakob disease 9.9
570 darier-white disease 9.9
571 exostoses, multiple, type i 9.9
572 glaucoma, primary open angle 9.9
573 immunoglobulin switch sequences 9.9
574 cholestasis, intrahepatic, of pregnancy, 1 9.9
575 leiomyoma, uterine 9.9
576 migraine with or without aura 1 9.9
577 neutrophil migration 9.9
578 parkinson disease, late-onset 9.9
579 pityriasis rubra pilaris 9.9
580 dowling-degos disease 1 9.9
581 vitiligo-associated multiple autoimmune disease susceptibility 6 9.9
582 chondrosarcoma 9.9
583 cystic fibrosis 9.9
584 enterocolitis 9.9
585 mucopolysaccharidosis, type vii 9.9
586 periodontitis, chronic 9.9
587 rhabdomyosarcoma 2 9.9
588 squamous cell carcinoma, head and neck 9.9
589 nuclear ribonucleic acid 9.9
590 kearns-sayre syndrome 9.9
591 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 9.9
592 helicobacter pylori infection 9.9
593 stroke, ischemic 9.9
594 astigmatism 9.9
595 langerhans cell histiocytosis 9.9
596 paragangliomas 3 9.9
597 vitiligo-associated multiple autoimmune disease susceptibility 1 9.9
598 anorexia nervosa 9.9
599 allergic rhinitis 9.9
600 coronary heart disease 1 9.9
601 psoriatic arthritis 9.9
602 hypertensive nephropathy 9.9
603 aplastic anemia 9.9
604 preterm premature rupture of the membranes 9.9
605 microvascular complications of diabetes 5 9.9
606 myelodysplastic syndrome 9.9
607 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.9
608 carbonic anhydrase va deficiency, hyperammonemia due to 9.9
609 neu-laxova syndrome 2 9.9
610 west syndrome 9.9
611 cryptogenic organizing pneumonia 9.9
612 funisitis 9.9
613 diffuse large b-cell lymphoma 9.9
614 good syndrome 9.9
615 brain glioma 9.9
616 apraxia 9.9
617 agraphia 9.9
618 ptosis 9.9
619 gallbladder disease 9.9
620 lymphoproliferative syndrome 9.9
621 cryptococcal meningitis 9.9
622 adenoid cystic carcinoma 9.9
623 thyroid gland anaplastic carcinoma 9.9
624 non-alcoholic steatohepatitis 9.9
625 parotitis 9.9
626 chronic meningitis 9.9
627 perforated corneal ulcer 9.9
628 gastrojejunal ulcer 9.9
629 acute salpingitis 9.9
630 prostatic hypertrophy 9.9
631 schizophreniform disorder 9.9
632 autonomic neuropathy 9.9
633 cicatricial pemphigoid 9.9
634 myopia 9.9
635 nephrotic syndrome 9.9
636 mononeuropathy 9.9
637 cryptococcosis 9.9
638 chagas disease 9.9
639 dengue disease 9.9
640 locked-in syndrome 9.9
641 dilated cardiomyopathy 9.9
642 transient global amnesia 9.9
643 balanitis 9.9
644 hellp syndrome 9.9
645 acute cystitis 9.9
646 typhoid fever 9.9
647 alexia 9.9
648 scleritis 9.9
649 cholestasis 9.9
650 lymphogranuloma venereum 9.9
651 multiple cranial nerve palsy 9.9
652 prostatitis 9.9
653 neuroendocrine tumor 9.9
654 retinal vein occlusion 9.9
655 malignant fibroxanthoma 9.9
656 cerebral palsy 9.9
657 vulva squamous cell carcinoma 9.9
658 dental caries 9.9
659 transient cerebral ischemia 9.9
660 lateral sclerosis 9.9
661 colon adenocarcinoma 9.9
662 arteriosclerosis 9.9
663 retinal vascular disease 9.9
664 chronic conjunctivitis 9.9
665 basal cell carcinoma 9.9
666 bilirubin metabolic disorder 9.9
667 idiopathic interstitial pneumonia 9.9
668 prostatic adenoma 9.9
669 bronchiolitis 9.9
670 pulmonary tuberculosis 9.9
671 cockayne syndrome 9.9
672 iga glomerulonephritis 9.9
673 allergic contact dermatitis 9.9
674 gallbladder cancer 9.9
675 lipid metabolism disorder 9.9
676 lysosomal storage disease 9.9
677 chronic granulomatous disease 9.9
678 teratocarcinoma 9.9
679 histiocytosis 9.9
680 viral laryngitis 9.9
681 mammary paget's disease 9.9
682 cranial nerve palsy 9.9
683 liver disease 9.9
684 primary syphilis 9.9
685 hyperglycemia 9.9
686 histiocytoma 9.9
687 carcinosarcoma 9.9
688 myofibroma 9.9
689 fibrous histiocytoma 9.9
690 dysgraphia 9.9
691 nominal aphasia 9.9
692 pleomorphic xanthoastrocytoma 9.9
693 ganglioglioma 9.9
694 blepharospasm 9.9
695 eyelid disease 9.9
696 salpingitis 9.9
697 cerebral lymphoma 9.9
698 esophageal disease 9.9
699 fibrillary astrocytoma 9.9
700 juvenile pilocytic astrocytoma 9.9
701 fibrous meningioma 9.9
702 meningothelial meningioma 9.9
703 hodgkin's lymphoma, lymphocytic-histiocytic predominance 9.9
704 chronic fatigue syndrome 9.9
705 lip cancer 9.9
706 tongue cancer 9.9
707 perinatal necrotizing enterocolitis 9.9
708 actinic keratosis 9.9
709 pityriasis rosea 9.9
710 mitochondrial encephalomyopathy 9.9
711 granuloma inguinale 9.9
712 ocular hypertension 9.9
713 infectious anterior uveitis 9.9
714 epiglottitis 9.9
715 epididymo-orchitis 9.9
716 cholangitis 9.9
717 deep keratitis 9.9
718 alopecia 9.9
719 chromosomal triplication 9.9
720 grover's disease 9.9
721 hydroa vacciniforme 9.9
722 med23 9.9
723 meningococcemia 9.9
724 mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes 9.9
725 neuromyelitis optica spectrum disorder 9.9
726 oral leukoplakia 9.9
727 pityriasis lichenoides 9.9
728 semantic dementia 9.9
729 undifferentiated pleomorphic sarcoma 9.9
730 weber syndrome 9.9
731 back pain 9.9
732 dysautonomia 9.9
733 febrile seizures 9.9
734 spasticity 9.9
735 tremor 9.9
736 paraneoplastic limbic encephalitis 9.9
737 acute transverse myelitis 9.9
738 congenital erosive and vesicular dermatosis 9.9
739 bickerstaff brainstem encephalitis 9.9
740 bullous impetigo 9.9
741 fungal keratitis 9.9
742 thrombotic microangiopathy 9.9
743 overgrowth syndrome 9.9
744 red cell aplasia 9.9
745 aniridia 1 9.8
746 aplasia cutis congenita, nonsyndromic 9.8
747 arteries, anomalies of 9.8
748 gastroesophageal reflux 9.8
749 progressive familial heart block, type ia 9.8
750 candidiasis, familial, 1 9.8
751 cleft palate, isolated 9.8
752 fibrosis of extraocular muscles, congenital, 1 9.8
753 corneal dystrophy, fuchs endothelial, 1 9.8
754 hand skill, relative 9.8
755 hemifacial spasm, familial 9.8
756 attention deficit-hyperactivity disorder 9.8
757 hypercholesterolemia, familial, 1 9.8
758 hypertension, essential 9.8
759 hypertriglyceridemia, familial 9.8
760 laryngeal abductor paralysis 9.8
761 nondisjunction 9.8
762 ocular cicatricial pemphigoid 9.8
763 otitis media 9.8
764 paget disease, extramammary 9.8
765 pulmonary fibrosis, idiopathic 9.8
766 schistosoma mansoni infection, susceptibility/ 9.8
767 schizophrenia 1 9.8
768 keratosis, seborrheic 9.8
769 sister chromatid exchange, frequency of 9.8
770 spinal arachnoiditis 9.8
771 sturge-weber syndrome 9.8
772 temporal arteritis 9.8
773 thrombocytopenia 2 9.8
774 tuberous sclerosis 1 9.8
775 von hippel-lindau syndrome 9.8
776 anencephaly 9.8
777 australia antigen 9.8
778 celiac disease 1 9.8
779 chordoma 9.8
780 cockayne syndrome a 9.8
781 constricting bands, congenital 9.8
782 corneal dystrophy, band-shaped 9.8
783 corneal endothelial dystrophy 9.8
784 persistent hyperplastic primary vitreous, autosomal recessive 9.8
785 lysinuric protein intolerance 9.8
786 neuropathy, hereditary sensory and autonomic, type iii 9.8
787 hemochromatosis, type 1 9.8
788 autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia 9.8
789 ichthyosis, congenital, autosomal recessive 4b 9.8
790 myelofibrosis 9.8
791 myxedema 9.8
792 3-methylglutaconic aciduria, type iii 9.8
793 orotic aciduria 9.8
794 insulin-like growth factor i 9.8
795 thrombotic thrombocytopenic purpura, congenital 9.8
796 xeroderma pigmentosum, complementation group f 9.8
797 mend syndrome 9.8
798 alpha-thalassemia/mental retardation syndrome, x-linked 9.8
799 hemophilia b 9.8
800 paine syndrome 9.8
801 reticuloendotheliosis, x-linked 9.8
802 aging 9.8
803 prostatic hyperplasia, benign 9.8
804 cd4/cd8 t-cell ratio 9.8
805 trichothiodystrophy 1, photosensitive 9.8
806 huntington disease-like 1 9.8
807 schizophrenia 2 9.8
808 omenn syndrome 9.8
809 microvascular complications of diabetes 1 9.8
810 alpha-thalassemia 9.8
811 progressive familial heart block, type ib 9.8
812 body mass index quantitative trait locus 1 9.8
813 inflammatory bowel disease 4 9.8
814 anxiety 9.8
815 endometrial cancer 9.8
816 leukemia, chronic myeloid 9.8
817 loeys-dietz syndrome 1 9.8
818 asthma-related traits 4 9.8
819 cavitary optic disc anomalies 9.8
820 ewing sarcoma 9.8
821 diabetes mellitus, ketosis-prone 9.8
822 myd88 deficiency 9.8
823 microvascular complications of diabetes 2 9.8
824 microvascular complications of diabetes 3 9.8
825 microvascular complications of diabetes 4 9.8
826 microvascular complications of diabetes 6 9.8
827 microvascular complications of diabetes 7 9.8
828 premature ovarian failure 7 9.8
829 fatty liver disease, nonalcoholic 1 9.8
830 gastric cancer 9.8
831 immunodeficiency 31b 9.8
832 cholangitis, primary sclerosing 9.8
833 hirschsprung disease, cardiac defects, and autonomic dysfunction 9.8
834 cyanosis, transient neonatal 9.8
835 microcephaly, epilepsy, and diabetes syndrome 9.8
836 infantile liver failure syndrome 1 9.8
837 erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige 9.8
838 seizures, scoliosis, and macrocephaly/microcephaly syndrome 9.8
839 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 9.8
840 hyperlipoproteinemia, type iii 9.8
841 mulchandani-bhoj-conlin syndrome 9.8
842 neuropathy, congenital hypomyelinating, 2 9.8
843 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.8
844 peripheral vascular disease 9.8
845 deficiency anemia 9.8
846 pulmonary hypertension 9.8
847 streptococcus pneumonia 9.8
848 pemphigus gestationis 9.8
849 livedoid vasculitis 9.8
850 chikungunya 9.8
851 epstein-barr virus hepatitis 9.8
852 trichomonas vaginalis trichomoniasis 9.8
853 foodborne botulism 9.8
854 familial adenomatous polyposis 9.8
855 lissencephaly 9.8
856 paralytic poliomyelitis 9.8
857 small cell carcinoma 9.8
858 peripheral t-cell lymphoma 9.8
859 metabolic acidosis 9.8
860 atrioventricular block 9.8
861 rheumatic heart disease 9.8
862 interleukin-7 receptor alpha deficiency 9.8
863 immunoglobulin alpha deficiency 9.8
864 cerebellar medulloblastoma 9.8
865 tactile agnosia 9.8
866 ileocolitis 9.8
867 crohn's colitis 9.8
868 atrial fibrillation 9.8
869 basal ganglia calcification 9.8
870 oral hairy leukoplakia 9.8
871 ectopic pregnancy 9.8
872 childhood acute lymphocytic leukemia 9.8
873 lymphoblastic lymphoma 9.8
874 meningococcal meningitis 9.8
875 igg4-related disease 9.8
876 hyper ige syndrome 9.8
877 cycloplegia 9.8
878 dysplastic nevus syndrome 9.8
879 cholelithiasis 9.8
880 thalassemia 9.8
881 louping ill 9.8
882 chronic leukemia 9.8
883 amyotrophic neuralgia 9.8
884 hypopyon 9.8
885 acute cervicitis 9.8
886 thrombotic thrombocytopenic purpura 9.8
887 murray valley encephalitis 9.8
888 western equine encephalitis 9.8
889 hand, foot and mouth disease 9.8
890 alport syndrome 9.8
891 chorioretinal scar 9.8
892 q fever 9.8
893 hydronephrosis 9.8
894 pulpitis 9.8
895 t cell deficiency 9.8
896 acute hemorrhagic conjunctivitis 9.8
897 cat-scratch disease 9.8
898 pneumocystosis 9.8
899 gingival recession 9.8
900 subdural empyema 9.8
901 pulmonary edema 9.8
902 hemopericardium 9.8
903 corneal abscess 9.8
904 cauda equina syndrome 9.8
905 penile cancer 9.8
906 leukocoria 9.8
907 splenic sequestration 9.8
908 chronic laryngitis 9.8
909 pericardial effusion 9.8
910 cortical blindness 9.8
911 coronary artery anomaly 9.8
912 ecthyma 9.8
913 pulmonary alveolar proteinosis 9.8
914 neurogenic bladder 9.8
915 low compliance bladder 9.8
916 arachnoiditis 9.8
917 otosclerosis 9.8
918 primary biliary cirrhosis 9.8
919 anisometropia 9.8
920 corneal degeneration 9.8
921 complex partial epilepsy 9.8
922 dysentery 9.8
923 spastic entropion 9.8
924 entropion 9.8
925 hepatic coma 9.8
926 pyloric stenosis 9.8
927 blastomycosis 9.8
928 tolosa-hunt syndrome 9.8
929 quadriplegia 9.8
930 miller fisher syndrome 9.8
931 conduct disorder 9.8
932 dementia 9.8
933 periventricular leukomalacia 9.8
934 branch retinal artery occlusion 9.8
935 central retinal artery occlusion 9.8
936 focal segmental glomerulosclerosis 9.8
937 esophageal candidiasis 9.8
938 megaesophagus 9.8
939 right bundle branch block 9.8
940 porphyria 9.8
941 cutaneous porphyria 9.8
942 klebsiella pneumonia 9.8
943 congenital toxoplasmosis 9.8
944 pure red-cell aplasia 9.8
945 tuberous sclerosis 9.8
946 kwashiorkor 9.8
947 alveolar periostitis 9.8
948 eclampsia 9.8
949 mature cataract 9.8
950 facial neuralgia 9.8
951 sick sinus syndrome 9.8
952 amenorrhea 9.8
953 schistosomiasis 9.8
954 geniculate ganglionitis 9.8
955 obstructive hydrocephalus 9.8
956 sclerosing cholangitis 9.8
957 pleuropneumonia 9.8
958 generalized anxiety disorder 9.8
959 corneal ectasia 9.8
960 cerebral degeneration 9.8
961 pemphigoid gestationis 9.8
962 niemann-pick disease 9.8
963 reye syndrome 9.8
964 hypothyroidism 9.8
965 lymphangioma 9.8
966 avoidant personality disorder 9.8
967 personality disorder 9.8
968 pleural disease 9.8
969 angioedema 9.8
970 alcohol use disorder 9.8
971 rheumatic disease 9.8
972 acute chest syndrome 9.8
973 rheumatic fever 9.8
974 thrombocytopenia due to platelet alloimmunization 9.8
975 endogenous depression 9.8
976 mental depression 9.8
977 breast fibroadenoma 9.8
978 pneumothorax 9.8
979 ichthyosis 9.8
980 richter's syndrome 9.8
981 peritoneum cancer 9.8
982 histoplasmosis 9.8
983 mitral valve stenosis 9.8
984 cheilitis 9.8
985 conversion disorder 9.8
986 neuroendocrine carcinoma 9.8
987 calcinosis 9.8
988 mononeuritis multiplex 9.8
989 bone cancer 9.8
990 leiomyosarcoma 9.8
991 enthesopathy 9.8
992 autoimmune hepatitis 9.8
993 hereditary multiple exostoses 9.8
994 intestinal perforation 9.8
995 b cell deficiency 9.8
996 ectodermal dysplasia 9.8
997 vulvovaginal candidiasis 9.8
998 polyclonal hypergammaglobulinemia 9.8
999 central retinal vein occlusion 9.8
1000 psychotic disorder 9.8
1001 hemangioma 9.8
1002 granulomatous angiitis 9.8
1003 corneal dystrophy 9.8
1004 rhizomelic chondrodysplasia punctata 9.8
1005 transitional cell carcinoma 9.8
1006 synovitis 9.8
1007 tic disorder 9.8
1008 cerebellar disease 9.8
1009 bronchiolitis obliterans 9.8
1010 acute interstitial pneumonia 9.8
1011 nonspecific interstitial pneumonia 9.8
1012 hemoglobinopathy 9.8
1013 endometrial adenocarcinoma 9.8
1014 severe acute respiratory syndrome 9.8
1015 antiphospholipid syndrome 9.8
1016 substance abuse 9.8
1017 interstitial lung disease 9.8
1018 gingival overgrowth 9.8
1019 spinal cord disease 9.8
1020 central nervous system lymphoma 9.8
1021 embryonal rhabdomyosarcoma 9.8
1022 hyper ige recurrent infection syndrome 1 9.8
1023 monkeypox 9.8
1024 teratoma 9.8
1025 palmoplantar keratosis 9.8
1026 breast disease 9.8
1027 uveal disease 9.8
1028 sagittal sinus thrombosis 9.8
1029 gastric adenocarcinoma 9.8
1030 plasmacytoma 9.8
1031 pulmonary fibrosis 9.8
1032 pleural empyema 9.8
1033 porokeratosis 9.8
1034 arthropathy 9.8
1035 pituitary adenoma 9.8
1036 childhood medulloblastoma 9.8
1037 thrombophlebitis 9.8
1038 insulinoma 9.8
1039 acute myocarditis 9.8
1040 skeletal muscle neoplasm 9.8
1041 mutism 9.8
1042 brain stem glioma 9.8
1043 anal margin carcinoma 9.8
1044 polyradiculopathy 9.8
1045 intracranial embolism 9.8
1046 neuromuscular disease 9.8
1047 avian influenza 9.8
1048 ludwig's angina 9.8
1049 adenosquamous carcinoma 9.8
1050 gerstmann syndrome 9.8
1051 prosopagnosia 9.8
1052 elephantiasis 9.8
1053 thoracic cancer 9.8
1054 pleural cancer 9.8
1055 demyelinating polyneuropathy 9.8
1056 von economo's disease 9.8
1057 central nervous system vasculitis 9.8
1058 colonic disease 9.8
1059 schizoaffective disorder 9.8
1060 dystonia 9.8
1061 keratinizing squamous cell carcinoma 9.8
1062 malignant syringoma 9.8
1063 endocervicitis 9.8
1064 malignant peripheral nerve sheath tumor 9.8
1065 congestive heart failure 9.8
1066 viral esophagitis 9.8
1067 fibromyalgia 9.8
1068 clivus chordoma 9.8
1069 adenoma 9.8
1070 spinal stenosis 9.8
1071 juvenile rheumatoid arthritis 9.8
1072 inverted follicular keratosis 9.8
1073 premenstrual tension 9.8
1074 active peptic ulcer disease 9.8
1075 acute endometritis 9.8
1076 gastrointestinal system disease 9.8
1077 intraocular lymphoma 9.8
1078 placenta disease 9.8
1079 end stage renal failure 9.8
1080 chronic kidney disease 9.8
1081 carotid artery occlusion 9.8
1082 osteoarthritis 9.8
1083 intestinal obstruction 9.8
1084 retinal artery occlusion 9.8
1085 mucormycosis 9.8
1086 oropharynx cancer 9.8
1087 duodenitis 9.8
1088 bacterial pneumonia 9.8
1089 intermediate coronary syndrome 9.8
1090 rosacea 9.8
1091 dermatophytosis 9.8
1092 learning disability 9.8
1093 narcolepsy 9.8
1094 degenerative disc disease 9.8
1095 achalasia 9.8
1096 amebiasis 9.8
1097 diabetic macular edema 9.8
1098 speech disorder 9.8
1099 herpes zoster oticus 9.8
1100 cleft lip 9.8
1101 scotoma 9.8
1102 fuchs' heterochromic uveitis 9.8
1103 acute laryngitis 9.8
1104 ulcerative blepharitis 9.8
1105 dacryoadenitis 9.8
1106 venezuelan equine encephalitis 9.8
1107 fasciitis 9.8
1108 necrotizing fasciitis 9.8
1109 ophthalmia neonatorum 9.8
1110 bacterial conjunctivitis 9.8
1111 trichinosis 9.8
1112 hemophilia 9.8
1113 ankrd26-related thrombocytopenia 9.8
1114 hereditary multiple osteochondromas 9.8
1115 sickle cell disease 9.8
1116 actinic cheilitis 9.8
1117 anaplastic oligoastrocytoma 9.8
1118 carotidynia 9.8
1119 catastrophic antiphospholipid syndrome 9.8
1120 cerebrospinal fluid leak 9.8
1121 charles bonnet syndrome 9.8
1122 diffuse intrinsic pontine glioma 9.8
1123 drug reaction with eosinophilia and systemic symptoms 9.8
1124 eosinophilic pustular folliculitis 9.8
1125 familial episodic pain syndrome 9.8
1126 febrile ulceronecrotic mucha-habermann disease 9.8
1127 fibromatosis 9.8
1128 foix chavany marie syndrome 9.8
1129 gianotti crosti syndrome 9.8
1130 giant cell myocarditis 9.8
1131 granulomatous rosacea 9.8
1132 herpes simiae 9.8
1133 human t-cell leukemia virus type 1 9.8
1134 infantile digital fibromatosis 9.8
1135 lymphoma aids related 9.8
1136 lymphosarcoma 9.8
1137 macrophage activation syndrome 9.8
1138 malakoplakia 9.8
1139 mallory-weiss syndrome 9.8
1140 mast cell activation syndrome 9.8
1141 meningococcal infection 9.8
1142 microencephaly 9.8
1143 mycobacterium chelonae 9.8
1144 neural crest tumor 9.8
1145 new-onset refractory status epilepticus 9.8
1146 oligoastrocytoma 9.8
1147 oral lichen planus 9.8
1148 parainfluenza virus type 3 9.8
1149 pityriasis lichenoides chronica 9.8
1150 pityriasis lichenoides et varioliformis acuta 9.8
1151 post-traumatic epilepsy 9.8
1152 pseudobulbar affect 9.8
1153 pure autonomic failure 9.8
1154 pustular psoriasis 9.8
1155 recurrent respiratory papillomatosis 9.8
1156 soft tissue sarcoma 9.8
1157 ulcerative proctitis 9.8
1158 wallerian degeneration 9.8
1159 wells syndrome 9.8
1160 woolly hair syndrome 9.8
1161 depression 9.8
1162 multiple endocrine neoplasia 9.8
1163 autonomic dysfunction 9.8
1164 hemifacial spasm 9.8
1165 hypersomnia 9.8
1166 occipital neuralgia 9.8
1167 persistent vegetative state 9.8
1168 pituitary tumors 9.8
1169 postinfectious encephalomyelitis 9.8
1170 traumatic brain injury 9.8
1171 atopic keratoconjunctivitis 9.8
1172 non-herpetic acute limbic encephalitis 9.8
1173 rare viral disease 9.8
1174 cleft lip/palate 9.8
1175 secondary hemophagocytic lymphohistiocytosis 9.8
1176 high-grade astrocytoma 9.8
1177 low-grade astrocytoma 9.8
1178 obsolete: atypical teratoid/rhabdoid tumor 9.8
1179 rare lymphatic malformation 9.8
1180 cranial neuralgia 9.8
1181 t-b- severe combined immunodeficiency 9.8
1182 gastric adenocarcinoma and proximal polyposis of the stomach 9.8
1183 non-infectious anterior uveitis 9.8
1184 igg4-related ophthalmic disease 9.8
1185 malignant tumor of penis 9.8
1186 persistent idiopathic facial pain 9.8
1187 paraneoplastic pemphigus 9.8
1188 argyria 9.8
1189 pneumococcal meningitis 9.8
1190 superficial pemphigus 9.8
1191 pemphigus vegetans 9.8
1192 erythrokeratoderma 9.8
1193 epidermal disease 9.8
1194 postinfectious encephalitis 9.8
1195 cardiogenic shock 9.8
1196 polyploidy 9.8
1197 rickettsial disease 9.8
1198 polyendocrinopathy 9.8

Graphical network of the top 20 diseases related to Herpes Simplex:



Diseases related to Herpes Simplex

Symptoms & Phenotypes for Herpes Simplex

UMLS symptoms related to Herpes Simplex:


fever, pruritus, halitosis, snoring, pelvic pain

GenomeRNAi Phenotypes related to Herpes Simplex according to GeneCards Suite gene sharing:

26 (showing 9, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 10.36 EIF2AK2 TBK1
2 Decreased viability GR00221-A-2 10.36 EIF2AK2 TBK1
3 Decreased viability GR00221-A-3 10.36 EIF2AK2
4 Decreased viability GR00221-A-4 10.36 EIF2AK2
5 Decreased viability GR00301-A 10.36 EIF2AK2 TBK1
6 Decreased viability GR00342-S-1 10.36 EIF2AK2 TBK1 TLR3
7 Decreased viability GR00342-S-2 10.36 EIF2AK2 TBK1 TLR3
8 Decreased viability GR00402-S-2 10.36 EIF2AK2 TBK1 TLR3 CREB3 DDX58 HCFC1
9 no effect GR00402-S-1 9.62 CREB3 DDX58 EIF2AK2 HCFC1 HCFC2 IFI16

MGI Mouse Phenotypes related to Herpes Simplex:

45 (showing 6, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.21 DDX58 EIF2AK2 IRF3 PILRA PML POU2F1
2 homeostasis/metabolism MP:0005376 10.13 CREB3 DDX58 HCFC2 IRF3 NECTIN1 PILRA
3 immune system MP:0005387 10.1 DDX58 EIF2AK2 HCFC2 IRF3 PILRA PML
4 mortality/aging MP:0010768 9.86 CREB3 DDX58 EIF2AK2 HCFC1 HCFC2 NECTIN1
5 liver/biliary system MP:0005370 9.76 DDX58 HCFC1 PILRA POU2F1 TBK1 TICAM1
6 neoplasm MP:0002006 9.1 DDX58 EIF2AK2 PML TAP1 TICAM1 TLR3

Drugs & Therapeutics for Herpes Simplex

Drugs for Herpes Simplex (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 273, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
2
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
3
Metronidazole Approved Phase 4 443-48-1 4173
4
Bisoprolol Approved Phase 4 66722-44-9 2405
5
Acyclovir Approved Phase 4 59277-89-3 2022
6
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
7
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
8
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
9
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
10
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
11
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
12 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
13
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
14
Difluprednate Approved Phase 4 23674-86-4 443936
15
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
16 Hydrocortisone hemisuccinate Phase 4
17 Hydrocortisone 17-butyrate 21-propionate Phase 4
18 Antiparasitic Agents Phase 4
19 Antiprotozoal Agents Phase 4
20 Denatonium Phase 4
21 Neurotransmitter Agents Phase 4
22 Sympatholytics Phase 4
23 Adrenergic Antagonists Phase 4
24 Adrenergic beta-1 Receptor Antagonists Phase 4
25 Adrenergic beta-Antagonists Phase 4
26 Hydrocortisone-17-butyrate Phase 4
27 Adrenergic Agents Phase 4
28 Antihypertensive Agents Phase 4
29 Ganciclovir triphosphate Phase 4
30 valacyclovir Phase 4
31 Protective Agents Phase 4
32 Anti-Inflammatory Agents Phase 4
33 Antiemetics Phase 4
34 Gastrointestinal Agents Phase 4
35 glucocorticoids Phase 4
36 Antineoplastic Agents, Hormonal Phase 4
37 BB 1101 Phase 4
38 Autonomic Agents Phase 4
39 Hormone Antagonists Phase 4
40 Hormones Phase 4
41 Methylprednisolone Acetate Phase 4
42 Neuroprotective Agents Phase 4
43 Ophthalmic Solutions Phase 4
44
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
45
Zinc Approved, Investigational Phase 3 7440-66-6 32051
46
Famciclovir Approved, Investigational Phase 3 104227-87-4 3324
47
Halofantrine Approved Phase 3 69756-53-2 37393
48
Aluminum sulfate Approved Phase 3 10043-01-3
49
Vidarabine Approved, Investigational Phase 3 24356-66-9 32326 21704
50
Sargramostim Approved, Investigational Phase 3 83869-56-1, 123774-72-1
51
Penciclovir Approved Phase 3 39809-25-1 4725
52
Sodium citrate Approved, Investigational Phase 3 68-04-2
53
Melphalan Approved Phase 3 148-82-3 4053 460612
54
Valganciclovir Approved, Investigational Phase 3 175865-60-8 64147
55
Citric acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
56 Dermatologic Agents Phase 3
57 Anti-Allergic Agents Phase 3
58 Monophosphoryl lipid A Phase 3
59 polysaccharide-K Phase 3
60 5-((2-(6-Amino-9H-purin-9-yl) ethyl) amino)-1-pentanol Phase 3
61 Radiation-Protective Agents Phase 3
62 Interferon Inducers Phase 3
63 Citrate Phase 3
64
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
65
Clobetasol Approved, Experimental, Investigational Phase 2 25122-46-7, 25122-41-2 32798 5311051
66
Peginterferon alfa-2a Approved, Investigational Phase 1, Phase 2 198153-51-4 5360545
67
Foscarnet Approved Phase 2 63585-09-1, 4428-95-9 3415
68
nivolumab Approved Phase 1, Phase 2 946414-94-4
69
Talimogene laherparepvec Approved, Experimental, Investigational Phase 1, Phase 2 1187560-31-1
70
Paclitaxel Approved, Vet_approved Phase 1, Phase 2 33069-62-4 36314
71
Progesterone Approved, Vet_approved Phase 1, Phase 2 57-83-0 5994
72
Pembrolizumab Approved Phase 2 1374853-91-4
73
Digoxin Approved Phase 2 20830-75-5 30322 2724385
74
Fludarabine Approved Phase 2 21679-14-1, 75607-67-9 30751
75
Busulfan Approved, Investigational Phase 2 55-98-1 2478