HZO
MCID: HRP011
MIFTS: 23

Herpes Zoster Ophthalmicus (HZO)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Herpes Zoster Ophthalmicus

MalaCards integrated aliases for Herpes Zoster Ophthalmicus:

Name: Herpes Zoster Ophthalmicus 52 71
Hzo 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 71 C0019364

Summaries for Herpes Zoster Ophthalmicus

MalaCards based summary : Herpes Zoster Ophthalmicus, also known as hzo, is related to herpes zoster and chickenpox. The drugs valacyclovir and Antiviral Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and liver.

Wikipedia : 74 Herpes zoster ophthalmicus (HZO), also known as ophthalmic zoster, is shingles involving the eye.... more...

Related Diseases for Herpes Zoster Ophthalmicus

Diseases related to Herpes Zoster Ophthalmicus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 167)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 12.2
2 chickenpox 11.0
3 keratitis, hereditary 11.0
4 uveitis 10.9
5 kearns-sayre syndrome 10.9
6 exanthem 10.9
7 iridocyclitis 10.8
8 hemiplegia 10.8
9 postherpetic neuralgia 10.8
10 neuritis 10.7
11 ptosis 10.7
12 myositis 10.7
13 optic neuritis 10.6
14 vasculitis 10.6
15 scleritis 10.6
16 orbital plasma cell granuloma 10.6
17 exophthalmos 10.6
18 encephalitis 10.6
19 iritis 10.6
20 optic nerve disease 10.6
21 neurotrophic keratopathy 10.6
22 keratopathy 10.6
23 conjunctivitis 10.6
24 acquired immunodeficiency syndrome 10.5
25 neuropathy 10.5
26 dacryoadenitis 10.5
27 immune deficiency disease 10.4
28 human immunodeficiency virus type 1 10.4
29 meningoencephalitis 10.4
30 abducens nerve disease 10.4
31 branch retinal artery occlusion 10.4
32 central retinal artery occlusion 10.4
33 acute retrobulbar neuritis 10.4
34 granulomatous angiitis 10.4
35 eye disease 10.4
36 retinal artery occlusion 10.4
37 herpes simplex 10.4
38 headache 10.4
39 3-methylglutaconic aciduria, type iii 10.4
40 stroke, ischemic 10.4
41 neuroretinitis 10.4
42 corneal ulcer 10.4
43 anisocoria 10.3
44 retinal detachment 10.3
45 yemenite deaf-blind hypopigmentation syndrome 10.3
46 intraocular pressure quantitative trait locus 10.3
47 aphasia 10.3
48 parotitis 10.3
49 cerebral arteritis 10.3
50 cicatricial ectropion 10.3

Graphical network of the top 20 diseases related to Herpes Zoster Ophthalmicus:



Diseases related to Herpes Zoster Ophthalmicus

Symptoms & Phenotypes for Herpes Zoster Ophthalmicus

Drugs & Therapeutics for Herpes Zoster Ophthalmicus

Drugs for Herpes Zoster Ophthalmicus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 valacyclovir Phase 4
2 Antiviral Agents Phase 4
3 Anti-Infective Agents Phase 4
4
Ganciclovir Approved, Investigational Phase 2 82410-32-0 3454
5 Ganciclovir triphosphate Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long-term Suppressive Valacyclovir Treatment for Herpes Zoster Ophthalmicus Recruiting NCT03134196 Phase 4 Masked Placebo;Masked Oral Valacyclovir
2 A Prospective, Double-masked, Placebo Controlled Comparison of Topical 0.15% Gancyclovir Gel (Zirgan) Versus 0.3% Hypromellose Gel (Genteal Gel; Placebo) for the Treatment of Herpes Zoster Keratitis Recruiting NCT02382588 Phase 2 gancyclovir gel;Hypromellose gel

Search NIH Clinical Center for Herpes Zoster Ophthalmicus

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Acyclovir
Acyclovir Sodium

Genetic Tests for Herpes Zoster Ophthalmicus

Anatomical Context for Herpes Zoster Ophthalmicus

MalaCards organs/tissues related to Herpes Zoster Ophthalmicus:

40
Eye, Skin, Liver, Lung, Bone Marrow, Bone, Brain

Publications for Herpes Zoster Ophthalmicus

Articles related to Herpes Zoster Ophthalmicus:

(show top 50) (show all 723)
# Title Authors PMID Year
1
Acute orbital myositis preceding vesicular rash eruption in herpes zoster ophthalmicus. 61
31879064 2020
2
Enrollment in the Zoster Eye Disease Study. 61
32558726 2020
3
Oculomotor nerve palsy in herpes zoster ophthalmicus: Presentation of 4 cases. 61
32505385 2020
4
Crossed Zoster Syndrome: A Rare Clinical Presentation Following Herpes Zoster Ophthalmicus. 61
32389129 2020
5
Seasonality of herpes zoster and herpes zoster ophthalmicus. 61
32151977 2020
6
Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report. 61
31883780 2020
7
Viral Kerato-Uveitis with Choroidal Vitiligo. 61
32255709 2020
8
Corneal Neurotization for Postherpetic Neurotrophic Keratopathy: Initial Experience and Clinical Outcomes. 61
32332687 2020
9
Isolated Internal Ophthalmoplegia Secondary to Herpes Zoster Ophthalmicus: A Rare Case Report. 61
32395161 2020
10
Conjunctival swab sample using varicella-zoster virus antigen kit enables rapid diagnosis of herpes zoster ophthalmicus. 61
32314351 2020
11
Incidence Rate of Herpes Zoster Ophthalmicus: A Retrospective Cohort Study from 1994 through 2018. 61
31668889 2020
12
Characteristics, treatment and complications of herpes zoster ophthalmicus at a tertiary eye hospital. 61
32200560 2020
13
Recurrent Herpes Zoster Ophthalmicus in a Patient With a Novel Toll-Like Receptor 3 Variant Linked to Compromised Activation Capacity in Fibroblasts. 61
31268141 2020
14
Herpes Zoster Ophthalmicus with Unilateral Sixth Nerve Palsy. 61
31852560 2020
15
Incidence Rate of Herpes Zoster Ophthalmicus. 61
32087873 2020
16
Vaccine-Strain Herpes Zoster Ophthalmicus in a 14-month-old Boy Prompting an Immunodeficiency Workup: Case Report and Review of Vaccine-strain Herpes Zoster. 61
31929435 2020
17
Eyelid and Orbital Involvement in HIV Infection - An African Perspective. 61
32058857 2020
18
Herpes zoster keratouveitis with hypopyon and hyphema. 61
32309125 2020
19
Higher risk of herpes zoster in stroke patients. 61
32017810 2020
20
How to manage herpes zoster ophthalmicus. 61
32395029 2020
21
Herpetic optic perineuritis presenting as classic abducens nerve palsy. 61
31998527 2020
22
Serological response to three alternative series of hepatitis B revaccination (Fendrix, Twinrix, and HBVaxPro-40) in healthy non-responders: a multicentre, open-label, randomised, controlled, superiority trial. 61
31629649 2020
23
Long-term outcomes of penetrating keratoplasty for corneal complications of herpes zoster ophthalmicus. 61
30733209 2019
24
Recurrent herpes zoster ophthalmicus in a young, healthy individual taking high doses of l-Arginine. 61
31497676 2019
25
A Case of Disseminated Zoster in an Immunocompetent Patient. 61
31911878 2019
26
Bilateral Scalp Necrosis in Giant Cell Arteritis. 61
31633591 2019
27
Herpes Zoster Ophthalmicus Review and Prevention. 61
30844951 2019
28
Morphea «En Coup De Sabre» at the Site of Healed Herpes Zoster Ophthalmicus. 61
30201544 2019
29
Herpes zoster ophthalmicus pseudodendrites: For topical antivirals or not? 61
30850997 2019
30
Headache and vision changes in an elderly man with rheumatoid arthritis. 61
31117158 2019
31
Neurological and Ophthalmological Manifestations of Varicella Zoster Virus. 61
30188405 2019
32
Does Herpes Zoster Increase the Risk of Stroke and Myocardial Infarction? A Comprehensive Review. 61
31013629 2019
33
Simultaneous parotitis and ipsilateral herpes zoster ophthalmicus: coincidence? 61
30898945 2019
34
Increased risk of neovascular age-related macular degeneration in patients with herpes zoster ophthalmicus: a retrospective cohort study. 61
30218493 2019
35
[Herpes zoster ophthalmicus in an immunosuppressed patient]. 61
30097178 2019
36
Hutchinson's sign as a predictor of ocular impairment in herpes zoster ophthalmicus. 61
30029771 2019
37
[Herpes zoster ophthalmicus]. 61
29907452 2019
38
Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient. 61
30805235 2019
39
Herpes zoster ophthalmicus. 61
30655269 2019
40
Herpes Zoster Ophthalmicus, Central Retinal Artery Occlusion, and Neovascular Glaucoma in an Immunocompetent Individual. 61
30820294 2019
41
Central nervous system varicella zoster vasculopathy in an immunocompromised patient. 61
30701156 2019
42
A case of tri-segmental cranial nerve V herpes zoster. 61
31692667 2019
43
Current Practice Patterns and Opinions on the Management of Recent-Onset or Chronic Herpes Zoster Ophthalmicus of Zoster Eye Disease Study Investigators. 61
30157049 2019
44
When Zoster Virus Hides a Primary Brain Lymphoma. 61
31893207 2019
45
Maxillary Zoster and Neurotrophic Keratitis following Trigeminal Block. 61
31097946 2019
46
Using natural language processing for identification of herpes zoster ophthalmicus cases to support population-based study. 61
29920898 2019
47
Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis. 61
30361202 2018
48
Non-healing herpes zoster ophthalmicus. 61
30168898 2018
49
Ein nicht heilender Herpes zoster ophthalmicus. 61
30300490 2018
50
Herpes zoster ophthalmicus caught in the (Tr)act! 61
29987527 2018

Variations for Herpes Zoster Ophthalmicus

Expression for Herpes Zoster Ophthalmicus

Search GEO for disease gene expression data for Herpes Zoster Ophthalmicus.

Pathways for Herpes Zoster Ophthalmicus

GO Terms for Herpes Zoster Ophthalmicus

Sources for Herpes Zoster Ophthalmicus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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