HZO
MCID: HRP011
MIFTS: 24

Herpes Zoster Ophthalmicus (HZO)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Herpes Zoster Ophthalmicus

MalaCards integrated aliases for Herpes Zoster Ophthalmicus:

Name: Herpes Zoster Ophthalmicus 20 71
Hzo 20

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

UMLS 71 C0019364

Summaries for Herpes Zoster Ophthalmicus

MalaCards based summary : Herpes Zoster Ophthalmicus, also known as hzo, is related to herpes zoster and chickenpox. An important gene associated with Herpes Zoster Ophthalmicus is TLR3 (Toll Like Receptor 3). The drugs valacyclovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and bone marrow.

Wikipedia : 74 Herpes zoster ophthalmicus (HZO), also known as ophthalmic zoster, is shingles involving the eye.... more...

Related Diseases for Herpes Zoster Ophthalmicus

Diseases related to Herpes Zoster Ophthalmicus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 167)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 11.7
2 chickenpox 11.0
3 keratitis, hereditary 10.9
4 uveitis 10.9
5 kearns-sayre syndrome 10.9
6 exanthem 10.9
7 iridocyclitis 10.8
8 postherpetic neuralgia 10.8
9 hemiplegia 10.8
10 neuritis 10.7
11 ptosis 10.7
12 myositis 10.7
13 optic neuritis 10.6
14 orbital plasma cell granuloma 10.6
15 scleritis 10.6
16 exophthalmos 10.6
17 iritis 10.6
18 optic nerve disease 10.6
19 keratopathy 10.6
20 conjunctivitis 10.6
21 neurotrophic keratopathy 10.6
22 acquired immunodeficiency syndrome 10.5
23 encephalitis 10.5
24 vasculitis 10.5
25 neuropathy 10.5
26 dacryoadenitis 10.5
27 meningoencephalitis 10.4
28 abducens nerve disease 10.4
29 branch retinal artery occlusion 10.4
30 central retinal artery occlusion 10.4
31 acute retrobulbar neuritis 10.4
32 granulomatous angiitis 10.4
33 eye disease 10.4
34 retinal artery occlusion 10.4
35 herpes simplex 10.4
36 immune deficiency disease 10.4
37 3-methylglutaconic aciduria, type iii 10.4
38 neuroretinitis 10.4
39 cataract 10.4
40 corneal ulcer 10.4
41 anisocoria 10.3
42 retinal detachment 10.3
43 yemenite deaf-blind hypopigmentation syndrome 10.3
44 intraocular pressure quantitative trait locus 10.3
45 aphasia 10.3
46 parotitis 10.3
47 cerebral arteritis 10.3
48 cicatricial ectropion 10.3
49 ectropion 10.3
50 retinitis 10.3

Graphical network of the top 20 diseases related to Herpes Zoster Ophthalmicus:



Diseases related to Herpes Zoster Ophthalmicus

Symptoms & Phenotypes for Herpes Zoster Ophthalmicus

Drugs & Therapeutics for Herpes Zoster Ophthalmicus

Drugs for Herpes Zoster Ophthalmicus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 valacyclovir Phase 4
2
Ganciclovir Approved, Investigational Phase 2 82410-32-0 3454
3 Anti-Infective Agents Phase 2
4 Antiviral Agents Phase 2
5 Ganciclovir triphosphate Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Long-term Suppressive Valacyclovir Treatment for Herpes Zoster Ophthalmicus Recruiting NCT03134196 Phase 4 Masked Placebo;Masked Oral Valacyclovir
2 A Prospective, Double-masked, Placebo Controlled Comparison of Topical 0.15% Gancyclovir Gel (Zirgan) Versus 0.3% Hypromellose Gel (Genteal Gel; Placebo) for the Treatment of Herpes Zoster Keratitis Terminated NCT02382588 Phase 2 gancyclovir gel;Hypromellose gel

Search NIH Clinical Center for Herpes Zoster Ophthalmicus

Inferred drug relations via UMLS 71 / NDF-RT 51 :


Acyclovir
Acyclovir Sodium

Genetic Tests for Herpes Zoster Ophthalmicus

Anatomical Context for Herpes Zoster Ophthalmicus

MalaCards organs/tissues related to Herpes Zoster Ophthalmicus:

40
Eye, Skin, Bone Marrow, Cortex, Retina, Myeloid

Publications for Herpes Zoster Ophthalmicus

Articles related to Herpes Zoster Ophthalmicus:

(show top 50) (show all 750)
# Title Authors PMID Year
1
Ethylenediaminetetraacetic Acid Chelation in Herpes Zoster Ophthalmicus Is Associated With a High Rate of Corneal Melt and Perforation. 61
33264147 2021
2
Bilateral Scalp Necrosis in Giant Cell Arteritis. 61
31633591 2021
3
Presumed Herpes Zoster Ophthalmicus Reactivation Following Recombinant Zoster Vaccination. 61
32947398 2021
4
Herpes zoster ophthalmicus clinical presentation and risk factors for loss of vision. 61
33571476 2021
5
Text-Based Identification of Herpes Zoster Ophthalmicus With Ocular Involvement in the Electronic Health Record: A Population-Based Study. 61
33575426 2021
6
Corneal Neurotization for Postherpetic Neurotrophic Keratopathy: Initial Experience and Clinical Outcomes. 61
32332687 2021
7
Orbital myositis with herpes zoster ophthalmicus. 61
33509965 2021
8
[A case of advanced pancreatic cancer with oculomotor nerve palsy caused by herpes zoster after introduction of gemcitabine plus nab-paclitaxel]. 61
33431754 2021
9
ACUTE RETINAL NECROSIS AND CONTRALATERAL CUTANEOUS ERUPTION AFTER THE SHINGLES VACCINE. 61
29528885 2021
10
Successful oral treatment of third cranial nerve palsy and optic neuritis from neglected herpes zoster in an immunocompetent patient. 61
33294726 2020
11
SIADH in the context of localized Herpes-Zoster infection. 61
33295633 2020
12
Clinical course of von Szily reaction: Case report and comprehensive review of the literature. 61
33015408 2020
13
Ocular surgery after herpes simplex and herpes zoster keratitis. 61
32910331 2020
14
Teaching Neuroimages: Hutchinson's sign in herpes zoster ophthalmicus. 61
33268563 2020
15
Enrollment in the Zoster Eye Disease Study. 61
32558726 2020
16
Herpes zoster ophthalmicus in COVID-19 patients. 61
33040343 2020
17
Conjunctival swab sample using varicella-zoster virus antigen kit enables rapid diagnosis of herpes zoster ophthalmicus. 61
32314351 2020
18
[Ocular manifestations of viral diseases]. 61
33168354 2020
19
The Use of Systemic Steroids in the Treatment of Herpes Zoster Ophthalmicus-Related Ophthalmoplegia: Case Report and Case Meta-analysis. 61
33186598 2020
20
Eyelid and Orbital Involvement in HIV Infection - An African Perspective. 61
32058857 2020
21
Short-Term Peripheral Nerve Stimulation Relieve Pain for Elder Herpes Zoster Ophthalmicus Patients: A Retrospective Study. 61
33058443 2020
22
Characteristics, treatment and complications of herpes zoster ophthalmicus at a tertiary eye hospital. 61
32200560 2020
23
Crossed Zoster Syndrome: A Rare Clinical Presentation Following Herpes Zoster Ophthalmicus. 61
32389129 2020
24
Recalcitrant Herpes Zoster Ophthalmicus in a Patient Discovered to Have Underlying Functional Natural Killer Cell Deficiency. 61
32931349 2020
25
Twelve Children with Varicella Vaccine Meningitis: Neuropathogenesis of Reactivated Live Attenuated Varicella Vaccine Virus. 61
32992805 2020
26
Oculomotor nerve palsy in herpes zoster ophthalmicus: Presentation of 4 cases. 61
32505385 2020
27
Uveal Effusion Associated with Presumed Viral Encephalitis. 61
32816570 2020
28
Herpes zoster ophthalmicus with ocular involvement in overtreated hyperthyroidism. 61
32587196 2020
29
Orbital apex syndrome secondary to herpes zoster ophthalmicus. 61
32653313 2020
30
Study of ocular manifestations in tuberculosis and its association with HIV AIDS in a tertiary care hospital. 61
32825858 2020
31
Herpes Zoster Ophthalmicus and Limbal Ischemia in A Patient with History of Ocular Graft-Versus-Host Disease. 61
32775806 2020
32
Acute orbital myositis preceding vesicular rash eruption in herpes zoster ophthalmicus. 61
31879064 2020
33
Seasonality of herpes zoster and herpes zoster ophthalmicus. 61
32151977 2020
34
Bihemisphere Ischemia Due to a Unilateral Lesion: A Case Report. 61
31883780 2020
35
Viral Kerato-Uveitis with Choroidal Vitiligo. 61
32255709 2020
36
Isolated Internal Ophthalmoplegia Secondary to Herpes Zoster Ophthalmicus: A Rare Case Report. 61
32395161 2020
37
Herpes zoster in the ophthalmic branch of the trigeminal ganglia obscuring cavernous sinus thrombosis due to Streptococcus constellatus subsp. constellatus - A case report. 61
33329815 2020
38
Herpes Zoster Ophthalmicus with Unilateral Sixth Nerve Palsy. 61
31852560 2020
39
Recurrent Herpes Zoster Ophthalmicus in a Patient With a Novel Toll-Like Receptor 3 Variant Linked to Compromised Activation Capacity in Fibroblasts. 61
31268141 2020
40
Incidence Rate of Herpes Zoster Ophthalmicus: A Retrospective Cohort Study from 1994 through 2018. 61
31668889 2020
41
Incidence Rate of Herpes Zoster Ophthalmicus. 61
32087873 2020
42
Vaccine-Strain Herpes Zoster Ophthalmicus in a 14-month-old Boy Prompting an Immunodeficiency Workup: Case Report and Review of Vaccine-strain Herpes Zoster. 61
31929435 2020
43
Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine. 61
33457029 2020
44
Herpes zoster keratouveitis with hypopyon and hyphema. 61
32309125 2020
45
Higher risk of herpes zoster in stroke patients. 61
32017810 2020
46
How to manage herpes zoster ophthalmicus. 61
32395029 2020
47
Clinical Efficacy of Short-Term Peripheral Nerve Stimulation in Management of Facial Pain Associated With Herpes Zoster Ophthalmicus. 61
33100962 2020
48
[Manifestations of herpes zoster ophthalmicus]. 61
33084284 2020
49
Supraorbital Nerve Radiofrequency for Severe Neuralgia Caused by Herpes Zoster Ophthalmicus. 61
33062083 2020
50
Serological response to three alternative series of hepatitis B revaccination (Fendrix, Twinrix, and HBVaxPro-40) in healthy non-responders: a multicentre, open-label, randomised, controlled, superiority trial. 61
31629649 2020

Variations for Herpes Zoster Ophthalmicus

Expression for Herpes Zoster Ophthalmicus

Search GEO for disease gene expression data for Herpes Zoster Ophthalmicus.

Pathways for Herpes Zoster Ophthalmicus

GO Terms for Herpes Zoster Ophthalmicus

Sources for Herpes Zoster Ophthalmicus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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