MCID: HRP037
MIFTS: 33

Herpes Zoster Oticus

Categories: Ear diseases, Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Herpes Zoster Oticus

MalaCards integrated aliases for Herpes Zoster Oticus:

Name: Herpes Zoster Oticus 12 74 52 53 43 15
Nervus Intermedius Neuralgia 12 52
Geniculate Herpes Zoster 12 17
Geniculate Neuralgia 12 52
Facial Nerve Palsy Due to Herpes Zoster Infection 52
Facial Nerve Paralysis Due to Vzv 52
Herpetic Geniculate Ganglionitis 12
Facial Nerve Palsy Due to Vzv 52
Ramsay Hunt Syndrome Type Ii 12
Ramsay Hunt Syndrome Type 2 12
Herpes Zoster Auricularis 12
Ramsay Hunt Syndrome Ii 53
Ramsay Hunt Syndrome 52
Ramsey Hunt Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9210
ICD9CM 34 053.11
MeSH 43 D016697
NCIt 49 C84763
SNOMED-CT 67 21954000
ICD10 32 B02.21
UMLS 71 C0017409

Summaries for Herpes Zoster Oticus

NIH Rare Diseases : 52 Herpes zoster oticus is a common complication of shingles , an infection caused by the varicella-zoster virus (which is the virus that also causes chickenpox ). Shingles occurs in people who have had chickenpox and in whom the varicella-zoster virus becomes active again. Herpes zoster oticus is caused by the spread of the virus to facial nerves and can cause intense ear pain; a rash around the ear, mouth, face, neck, and scalp; and paralysis of the face. Other symptoms may include hearing loss , vertigo (feeling that the room is spinning), tinnitus (hearing abnormal sounds), nausea, vomiting, loss of taste in the tongue, and dry mouth and eyes. Some cases of herpes zoster oticus do not require treatment, but when treatment is needed, pain medications, antiviral drugs or corticosteroids may be prescribed. Vertigo is sometimes treated with medication as well. The prognosis of herpes zoster oticus is typically good, but in some cases hearing loss or facial paralysis may be permanent.

MalaCards based summary : Herpes Zoster Oticus, also known as nervus intermedius neuralgia, is related to ramsay hunt syndrome i and myoclonus and ataxia, and has symptoms including vertigo, headache and tinnitus. An important gene associated with Herpes Zoster Oticus is MT-TC (Mitochondrially Encoded TRNA-Cys (UGU/C)). Affiliated tissues include facial nerve, eye and tongue.

Disease Ontology : 12 A viral infectious disease that results in inflammation located in facial nerve, which leads to paralysis of one side of the face, has material basis in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has symptom vesicular rash of the ear or mouth, has symptom tinnitus, has symptom vertigo, has symptom otalgia, and has symptom headache.

NINDS : 53 Herpes zoster oticus, also called Ramsay Hunt Syndrome or Ramsay Hunt Syndrome type II, is a common complication of shingles. Shingles is an infection caused by the varicella-zoster virus, which is the virus that causes chickenpox. Shingles occurs in people who have had chickenpox and represents a reactivation of the dormant varicella-zoster virus. Herpes zoster oticus, which is caused by the spread of the varicella-zoster virus to facial nerves, is characterized by intense ear pain, a rash around the ear, mouth, face, neck, and scalp, and paralysis of facial nerves. Other symptoms may include hearing loss, vertigo (abnormal sensation of movement), and tinnitus (abnormal sounds). Taste loss in the tongue and dry mouth and eyes may also occur.

Wikipedia : 74 Ramsay Hunt syndrome type 2, also known as herpes zoster oticus, is a disorder that is caused by the... more...

Related Diseases for Herpes Zoster Oticus

Diseases related to Herpes Zoster Oticus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 ramsay hunt syndrome i 12.8
2 myoclonus and ataxia 12.1
3 herpes zoster 11.2
4 facial paralysis 11.0
5 chickenpox 10.8
6 myoclonus 10.7
7 ataxia and polyneuropathy, adult-onset 10.7
8 bell's palsy 10.7
9 myoclonic cerebellar dyssynergia 10.6
10 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.6
11 polyneuropathy 10.5
12 exanthem 10.4
13 neuritis 10.4
14 trigeminal neuralgia 10.4
15 immune deficiency disease 10.4
16 mitochondrial encephalomyopathy 10.4
17 acoustic neuroma 10.4
18 neuroma 10.4
19 unverricht-lundborg syndrome 10.4
20 encephalitis 10.4
21 pathologic nystagmus 10.4
22 vestibular neuronitis 10.3
23 laryngitis 10.3
24 herpes simplex 10.3
25 myoclonus epilepsy 10.3
26 migraine with or without aura 1 10.3
27 migraine without aura 10.3
28 occipital neuralgia 10.3
29 glossopharyngeal neuralgia 10.3
30 rheumatoid arthritis 10.2
31 osteonecrosis 10.2
32 meningoencephalitis 10.2
33 aseptic meningitis 10.2
34 guillain-barre syndrome 10.2
35 labyrinthitis 10.2
36 pharyngitis 10.2
37 sensory peripheral neuropathy 10.2
38 inappropriate adh syndrome 10.2
39 progressive myoclonus epilepsy 10.2
40 47,xyy 10.2
41 sudden sensorineural hearing loss 10.2
42 hemifacial spasm, familial 10.2
43 kearns-sayre syndrome 10.2
44 branchiootic syndrome 1 10.2
45 sensorineural hearing loss 10.2
46 malignant otitis externa 10.2
47 optic neuritis 10.2
48 vestibulocochlear nerve disease 10.2
49 geniculate ganglionitis 10.2
50 optic nerve disease 10.2

Graphical network of the top 20 diseases related to Herpes Zoster Oticus:



Diseases related to Herpes Zoster Oticus

Symptoms & Phenotypes for Herpes Zoster Oticus

Symptoms:

12
  • vertigo
  • headache
  • tinnitus
  • vesicular rash of the ear
  • otalgia

Drugs & Therapeutics for Herpes Zoster Oticus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Complex Oro-Facial Pain: Functional Imaging Characterization and Treatment With Transcranial Magnetic Stimulation Completed NCT02633306

Search NIH Clinical Center for Herpes Zoster Oticus

Cochrane evidence based reviews: herpes zoster oticus

Genetic Tests for Herpes Zoster Oticus

Anatomical Context for Herpes Zoster Oticus

The Foundational Model of Anatomy Ontology organs/tissues related to Herpes Zoster Oticus:

19
Facial Nerve

MalaCards organs/tissues related to Herpes Zoster Oticus:

40
Eye, Tongue, Bone, Testes, Brain, Temporal Lobe

Publications for Herpes Zoster Oticus

Articles related to Herpes Zoster Oticus:

(show top 50) (show all 212)
# Title Authors PMID Year
1
Sydney Facial Nerve Clinic: experience of a multidisciplinary team. 61
32129559 2020
2
A Case of Nervus Intermedius Neuralgia. 61
31953093 2020
3
Multiple cranial nerve injury in Ramsay Hunt Syndrome: a case report. 61
32207443 2020
4
A Case of Disseminated Zoster in an Immunocompetent Patient. 61
31911878 2019
5
Atypical clinical manifestations of herpes zoster oticus: diagnostic usefulness of magnetic resonance imaging. 61
31278535 2019
6
Herpes Zoster Oticus, Ophthalmicus, and Cutaneous Disseminated: Case Report and Literature Review. 61
32165902 2019
7
The use of botulinum toxin type A in nervus intermedius neuralgia. 61
31771776 2019
8
[Primary Ewing's sarcoma of the temporal bone: a rare case]. 61
31914306 2019
9
Recovery of ocular and cervical vestibular evoked myogenic potentials after treatment of inner ear diseases. 61
31070081 2019
10
Herpes zoster oticus with meningitis masquerading as malignant otitis externa. 61
31177200 2019
11
Nerve Compression Syndromes in the Posterior Cranial Fossa. 61
30855007 2019
12
Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome. 61
31915561 2019
13
[From the Experts office: Auricular perichondritis or herpes zoster oticus? - Diagnostic error, diagnostic mistake, or deficient examination findings?] 61
30620967 2019
14
Ramsay Hunt syndrome. 61
30637343 2018
15
Cranial Neuralgias. 61
30074554 2018
16
Pain-free and pain-controlled survival after sectioning the nervus intermedius in nervus intermedius neuralgia: a single-institution review. 61
30117769 2018
17
Electroneurography in the acute stage of facial palsy as a predictive factor for the development of facial synkinesis sequela. 61
28966005 2018
18
The Neuralgias. 61
30116913 2018
19
Microvascular Decompression of Nervus Intermedius. 61
29729456 2018
20
A Very Rare Type of Neuralgia: Nervus Intermedius Neuralgia. 61
29033644 2017
21
Acute Facial Nerve Palsy With Ipsilateral Soft Palate Ulcers. 61
28388396 2017
22
Facial palsy and atrial fibrillation: a special case of Ramsay Hunt syndrome. 61
28705842 2017
23
Nervus Intermedius Neuralgia Treated with Microvascular Decompression: A Case Report and Review of the Literature. 61
28840083 2017
24
Other facial neuralgias. 61
28133989 2017
25
Facial paralysis due to Ramsay Hunt syndrome - A rare condition. 61
28614529 2017
26
A Case of Prethoracic Pain Radiating Upward and Initiating Nervus Intermedius Neuralgia and Migraine Headache: Could Epicrania Fugax Pain Start in the Upper Body? 61
28931106 2017
27
Isolated Deep Ear Canal Pain: Possible Role of Auricular Branch of Vagus Nerve-Case Illustrations with Cadaveric Correlation. 61
27593717 2016
28
Characteristics of hearing loss in patients with herpes zoster oticus. 61
27861389 2016
29
Temporal Lobe Retraction Provides Better Surgical Exposure of the Peri-Geniculate Ganglion for Facial Nerve Decompression via Transmastoid Approach. 61
27593878 2016
30
Clinical manifestations in patients with herpes zoster oticus. 61
26308524 2016
31
[The damage to the trigeminal nerve associated with herpetic viral infection in otorhinolaryngology]. 61
27500572 2016
32
Nervus intermedius neuralgia treated with tractotomy under intraoperative nerve electrophysiology monitoring. 61
26349469 2015
33
Cranial Neuralgias. 61
26252592 2015
34
Test battery of cranial nerves VII and VIII for assessing herpes zoster oticus. 61
25385809 2015
35
Painful rash of the auricle: Herpes zoster oticus. 61
25531857 2014
36
The neuralgias: diagnosis and management. 61
24797269 2014
37
Geniculate neuralgia: a systematic review. 61
24819337 2014
38
[Three cases of Ramsay-Hunt syndrome concurrent with ipsilateral vocal cord paralysis]. 61
25007684 2014
39
Vocal cord paralysis associated with Ramsay Hunt syndrome: looking back 50 years. 61
24503657 2014
40
Use of an artificial neural network for diagnosis of facial pain syndromes: an update. 61
24217113 2014
41
A case of generalized varicelliform eruption after herpes zoster oticus. 61
24335939 2014
42
Cranial neuralgias. 61
23809305 2013
43
The nervus intermedius: a review of its anatomy, function, pathology, and role in neurosurgery. 61
22484073 2013
44
Vestibular and cochlear neuritis in patients with Ramsay Hunt syndrome: a Gd-enhanced MRI study. 61
23237095 2013
45
Comparison of Transcranial Magnetic Stimulation and Electroneuronography Between Bell's Palsy and Ramsay Hunt Syndrome in Their Acute Stages. 61
23525840 2013
46
Contralateral botulinum toxin injection to improve facial asymmetry after acute facial paralysis. 61
23444480 2013
47
The central myelin-peripheral myelin transitional zone of the nervus intermedius and its implications for microsurgery in the cerebellopontine angle. 61
22190233 2012
48
Herpes zoster oticus: a clinical model for a transynaptic, reflex pathways, viral transmission hypotheses. 61
22709534 2012
49
Characteristics of adverse effects when using high dose short term steroid regimen. 61
24653873 2012
50
Herpes zoster oticus (Ramsay Hunt syndrome) in children: case report and literature review. 61
22445801 2012

Variations for Herpes Zoster Oticus

Expression for Herpes Zoster Oticus

Search GEO for disease gene expression data for Herpes Zoster Oticus.

Pathways for Herpes Zoster Oticus

GO Terms for Herpes Zoster Oticus

Biological processes related to Herpes Zoster Oticus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 8.8 SCYL3 SCN9A CD40LG

Sources for Herpes Zoster Oticus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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