MCID: HRP037
MIFTS: 31

Herpes Zoster Oticus

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Herpes Zoster Oticus

MalaCards integrated aliases for Herpes Zoster Oticus:

Name: Herpes Zoster Oticus 12 74 20 53 44 15
Nervus Intermedius Neuralgia 12 20
Geniculate Herpes Zoster 12 17
Geniculate Neuralgia 12 20
Facial Nerve Palsy Due to Herpes Zoster Infection 20
Facial Nerve Paralysis Due to Vzv 20
Herpetic Geniculate Ganglionitis 12
Facial Nerve Palsy Due to Vzv 20
Ramsay Hunt Syndrome Type Ii 12
Ramsay Hunt Syndrome Type 2 12
Herpes Zoster Auricularis 12
Ramsay Hunt Syndrome Ii 53
Ramsay Hunt Syndrome 20
Ramsey Hunt Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9210
ICD9CM 34 053.11
MeSH 44 D016697
NCIt 50 C84763
SNOMED-CT 67 21954000
ICD10 32 B02.21
UMLS 71 C0017409

Summaries for Herpes Zoster Oticus

GARD : 20 Herpes zoster oticus is a common complication of shingles, an infection caused by the varicella-zoster virus (which is the virus that also causes chickenpox). Shingles occurs in people who have had chickenpox and in whom the varicella-zoster virus becomes active again. Herpes zoster oticus is caused by the spread of the virus to facial nerves and can cause intense ear pain; a rash around the ear, mouth, face, neck, and scalp; and paralysis of the face. Other symptoms may include hearing loss, vertigo (feeling that the room is spinning), tinnitus (hearing abnormal sounds), nausea, vomiting, loss of taste in the tongue, and dry mouth and eyes. Some cases of herpes zoster oticus do not require treatment, but when treatment is needed, pain medications, antiviral drugs or corticosteroids may be prescribed. Vertigo is sometimes treated with medication as well. The prognosis of herpes zoster oticus is typically good, but in some cases hearing loss or facial paralysis may be permanent.

MalaCards based summary : Herpes Zoster Oticus, also known as nervus intermedius neuralgia, is related to ramsay hunt syndrome i and myoclonus and ataxia, and has symptoms including vertigo, headache and tinnitus. An important gene associated with Herpes Zoster Oticus is CCDC80 (Coiled-Coil Domain Containing 80). Affiliated tissues include facial nerve, tongue and temporal lobe.

Disease Ontology : 12 A viral infectious disease that results in inflammation located in facial nerve, which leads to paralysis of one side of the face, has material basis in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has symptom vesicular rash of the ear or mouth, has symptom tinnitus, has symptom vertigo, has symptom otalgia, and has symptom headache.

NINDS : 53 Herpes zoster oticus, also called Ramsay Hunt Syndrome or Ramsay Hunt Syndrome type II, is a common complication of shingles. Shingles is an infection caused by the varicella-zoster virus, which is the virus that causes chickenpox. Shingles occurs in people who have had chickenpox and represents a reactivation of the dormant varicella-zoster virus. Herpes zoster oticus, which is caused by the spread of the varicella-zoster virus to facial nerves, is characterized by intense ear pain, a rash around the ear, mouth, face, neck, and scalp, and paralysis of facial nerves. Other symptoms may include hearing loss, vertigo (abnormal sensation of movement), and tinnitus (abnormal sounds). Taste loss in the tongue and dry mouth and eyes may also occur.

Wikipedia : 74 Ramsay Hunt syndrome type 2, also known as herpes zoster oticus, is a disorder that is caused by the... more...

Related Diseases for Herpes Zoster Oticus

Diseases related to Herpes Zoster Oticus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 ramsay hunt syndrome i 11.6
2 myoclonus and ataxia 11.5
3 myoclonic cerebellar dyssynergia 11.3
4 herpes zoster 11.2
5 facial paralysis 10.9
6 chickenpox 10.7
7 myoclonus 10.7
8 ataxia and polyneuropathy, adult-onset 10.6
9 bell's palsy 10.6
10 polyneuropathy 10.4
11 mitochondrial encephalomyopathy 10.4
12 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.4
13 exanthem 10.4
14 neuritis 10.4
15 immune deficiency disease 10.4
16 disease by infectious agent 10.4
17 vestibular neuronitis 10.4
18 acoustic neuroma 10.4
19 neuroma 10.4
20 unverricht-lundborg syndrome 10.4
21 occipital neuralgia 10.3
22 trigeminal neuralgia 10.3
23 rheumatoid arthritis 10.3
24 laryngitis 10.3
25 herpes simplex 10.3
26 myoclonus epilepsy 10.3
27 encephalitis 10.3
28 pathologic nystagmus 10.3
29 osteonecrosis 10.2
30 meningoencephalitis 10.2
31 aseptic meningitis 10.2
32 guillain-barre syndrome 10.2
33 labyrinthitis 10.2
34 pharyngitis 10.2
35 sensory peripheral neuropathy 10.2
36 inappropriate adh syndrome 10.2
37 chronic kidney disease 10.2
38 arthritis 10.2
39 progressive myoclonus epilepsy 10.2
40 sudden sensorineural hearing loss 10.2
41 postherpetic neuralgia 10.2
42 migraine with or without aura 1 10.2
43 migraine without aura 10.2
44 hemifacial spasm, familial 10.1
45 kearns-sayre syndrome 10.1
46 branchiootic syndrome 1 10.1
47 sensorineural hearing loss 10.1
48 malignant otitis externa 10.1
49 optic neuritis 10.1
50 vestibulocochlear nerve disease 10.1

Graphical network of the top 20 diseases related to Herpes Zoster Oticus:



Diseases related to Herpes Zoster Oticus

Symptoms & Phenotypes for Herpes Zoster Oticus

Symptoms:

12
  • vertigo
  • headache
  • tinnitus
  • vesicular rash of the ear
  • otalgia

Drugs & Therapeutics for Herpes Zoster Oticus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Complex Oro-Facial Pain: Functional Imaging Characterization and Treatment With Transcranial Magnetic Stimulation Completed NCT02633306

Search NIH Clinical Center for Herpes Zoster Oticus

Cochrane evidence based reviews: herpes zoster oticus

Genetic Tests for Herpes Zoster Oticus

Anatomical Context for Herpes Zoster Oticus

The Foundational Model of Anatomy Ontology organs/tissues related to Herpes Zoster Oticus:

19
Facial Nerve

MalaCards organs/tissues related to Herpes Zoster Oticus:

40
Tongue, Temporal Lobe

Publications for Herpes Zoster Oticus

Articles related to Herpes Zoster Oticus:

(show top 50) (show all 223)
# Title Authors PMID Year
1
A pain in the ear: Two case reports of nervus intermedius neuralgia and narrative review. 61
33586784 2021
2
Endoscopy during neurotomy of the nervus intermedius for nervus intermedius neuralgia: a case report. 61
33569481 2021
3
Visualizing Affected Nerve Bundles of Cranial Nerves VII and VIII in Herpes Zoster Oticus. 61
32925867 2020
4
The use of botulinum toxin type A in nervus intermedius neuralgia. 61
31771776 2020
5
Vestibular and cochlear nerve enhancement on MRI and its correlation with vestibulocochlear functional deficits in patients with Ramsay Hunt syndrome. 61
32928603 2020
6
Visualizing Affected Nerve Bundles of Cranial Nerves VII and VIII in Herpes Zoster Oticus. 61
32590825 2020
7
Sydney Facial Nerve Clinic: experience of a multidisciplinary team. 61
32129559 2020
8
A Case of Nervus Intermedius Neuralgia. 61
31953093 2020
9
Multiple cranial nerve injury in Ramsay Hunt Syndrome: a case report. 61
32207443 2020
10
Ramsey hunt syndrome after antimonial treatment for American Cutaneous Leishmaniasis. 61
33206873 2020
11
A Case of Disseminated Zoster in an Immunocompetent Patient. 61
31911878 2019
12
Atypical clinical manifestations of herpes zoster oticus: diagnostic usefulness of magnetic resonance imaging. 61
31278535 2019
13
Herpes Zoster Oticus, Ophthalmicus, and Cutaneous Disseminated: Case Report and Literature Review. 61
32165902 2019
14
[Primary Ewing's sarcoma of the temporal bone: a rare case]. 61
31914306 2019
15
Recovery of ocular and cervical vestibular evoked myogenic potentials after treatment of inner ear diseases. 61
31070081 2019
16
Herpes zoster oticus with meningitis masquerading as malignant otitis externa. 61
31177200 2019
17
[From the Experts office: Auricular perichondritis or herpes zoster oticus? - Diagnostic error, diagnostic mistake, or deficient examination findings?] 61
30620967 2019
18
Nerve Compression Syndromes in the Posterior Cranial Fossa. 61
30855007 2019
19
Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome. 61
31915561 2019
20
Ramsay Hunt syndrome. 61
30637343 2018
21
Cranial Neuralgias. 61
30074554 2018
22
Pain-free and pain-controlled survival after sectioning the nervus intermedius in nervus intermedius neuralgia: a single-institution review. 61
30117769 2018
23
Electroneurography in the acute stage of facial palsy as a predictive factor for the development of facial synkinesis sequela. 61
28966005 2018
24
The Neuralgias. 61
30116913 2018
25
Microvascular Decompression of Nervus Intermedius. 61
29729456 2018
26
A Very Rare Type of Neuralgia: Nervus Intermedius Neuralgia. 61
29033644 2017
27
Acute Facial Nerve Palsy With Ipsilateral Soft Palate Ulcers. 61
28388396 2017
28
Facial palsy and atrial fibrillation: a special case of Ramsay Hunt syndrome. 61
28705842 2017
29
Nervus Intermedius Neuralgia Treated with Microvascular Decompression: A Case Report and Review of the Literature. 61
28840083 2017
30
Other facial neuralgias. 61
28133989 2017
31
Facial paralysis due to Ramsay Hunt syndrome - A rare condition. 61
28614529 2017
32
A Case of Prethoracic Pain Radiating Upward and Initiating Nervus Intermedius Neuralgia and Migraine Headache: Could Epicrania Fugax Pain Start in the Upper Body? 61
28931106 2017
33
Isolated Deep Ear Canal Pain: Possible Role of Auricular Branch of Vagus Nerve-Case Illustrations with Cadaveric Correlation. 61
27593717 2016
34
Characteristics of hearing loss in patients with herpes zoster oticus. 61
27861389 2016
35
Temporal Lobe Retraction Provides Better Surgical Exposure of the Peri-Geniculate Ganglion for Facial Nerve Decompression via Transmastoid Approach. 61
27593878 2016
36
Clinical manifestations in patients with herpes zoster oticus. 61
26308524 2016
37
[The damage to the trigeminal nerve associated with herpetic viral infection in otorhinolaryngology]. 61
27500572 2016
38
Nervus intermedius neuralgia treated with tractotomy under intraoperative nerve electrophysiology monitoring. 61
26349469 2015
39
Cranial Neuralgias. 61
26252592 2015
40
Test battery of cranial nerves VII and VIII for assessing herpes zoster oticus. 61
25385809 2015
41
Painful rash of the auricle: Herpes zoster oticus. 61
25531857 2014
42
The neuralgias: diagnosis and management. 61
24797269 2014
43
Geniculate neuralgia: a systematic review. 61
24819337 2014
44
[Three cases of Ramsay-Hunt syndrome concurrent with ipsilateral vocal cord paralysis]. 61
25007684 2014
45
Vocal cord paralysis associated with Ramsay Hunt syndrome: looking back 50 years. 61
24503657 2014
46
Use of an artificial neural network for diagnosis of facial pain syndromes: an update. 61
24217113 2014
47
A case of generalized varicelliform eruption after herpes zoster oticus. 61
24335939 2014
48
Cranial neuralgias. 61
23809305 2013
49
The nervus intermedius: a review of its anatomy, function, pathology, and role in neurosurgery. 61
22484073 2013
50
Vestibular and cochlear neuritis in patients with Ramsay Hunt syndrome: a Gd-enhanced MRI study. 61
23237095 2013

Variations for Herpes Zoster Oticus

Expression for Herpes Zoster Oticus

Search GEO for disease gene expression data for Herpes Zoster Oticus.

Pathways for Herpes Zoster Oticus

GO Terms for Herpes Zoster Oticus

Sources for Herpes Zoster Oticus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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