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MCID: HRP037
MIFTS: 33

Herpes Zoster Oticus

Categories: Ear diseases, Infectious diseases, Neuronal diseases, Rare diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes
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Aliases & Classifications for Herpes Zoster Oticus

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MalaCards integrated aliases for Herpes Zoster Oticus:

Name: Herpes Zoster Oticus 12 74 52 53 43
Geniculate Herpes Zoster 12 15 17
Nervus Intermedius Neuralgia 12 52
Geniculate Neuralgia 12 52
Facial Nerve Palsy Due to Herpes Zoster Infection 52
Facial Nerve Paralysis Due to Vzv 52
Herpetic Geniculate Ganglionitis 12
Facial Nerve Palsy Due to Vzv 52
Ramsay Hunt Syndrome Type Ii 12
Ramsay Hunt Syndrome Type 2 12
Herpes Zoster Auricularis 12
Ramsay Hunt Syndrome Ii 53
Ramsay Hunt Syndrome 52
Ramsey Hunt Syndrome 12

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Neuronal diseases Ear diseases
See all MalaCards categories (disease lists)


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Disease Ontology 12 DOID:9210
ICD9CM 34 053.11
MeSH 43 D016697
NCIt 49 C84763
SNOMED-CT 67 21954000
ICD10 32 B02.21
UMLS 71 C0017409
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Summaries for Herpes Zoster Oticus

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NIH Rare Diseases : 52 Herpes zoster oticus is a common complication of shingles , an infection caused by the varicella-zoster virus (which is the virus that also causes chickenpox ). Shingles occurs in people who have had chickenpox and in whom the varicella-zoster virus becomes active again. Herpes zoster oticus is caused by the spread of the virus to facial nerves and can cause intense ear pain; a rash around the ear, mouth, face, neck, and scalp; and paralysis of the face. Other symptoms may include hearing loss , vertigo (feeling that the room is spinning), tinnitus (hearing abnormal sounds), nausea, vomiting, loss of taste in the tongue, and dry mouth and eyes. Some cases of herpes zoster oticus do not require treatment, but when treatment is needed, pain medications, antiviral drugs or corticosteroids may be prescribed. Vertigo is sometimes treated with medication as well. The prognosis of herpes zoster oticus is typically good, but in some cases hearing loss or facial paralysis may be permanent.

MalaCards based summary : Herpes Zoster Oticus, also known as geniculate herpes zoster, is related to ramsay hunt syndrome i and obsolete: ramsay hunt syndrome type ii, and has symptoms including vertigo, headache and tinnitus. An important gene associated with Herpes Zoster Oticus is MT-TC (Mitochondrially Encoded TRNA-Cys (UGU/C)). Affiliated tissues include facial nerve, eye and tongue.

Disease Ontology : 12 A viral infectious disease that results in inflammation located in facial nerve, which leads to paralysis of one side of the face, has material basis in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has symptom vesicular rash of the ear or mouth, has symptom tinnitus, has symptom vertigo, has symptom otalgia, and has symptom headache.

NINDS : 53 Herpes zoster oticus, also called Ramsay Hunt Syndrome or Ramsay Hunt Syndrome type II, is a common complication of shingles. Shingles is an infection caused by the varicella-zoster virus, which is the virus that causes chickenpox. Shingles occurs in people who have had chickenpox and represents a reactivation of the dormant varicella-zoster virus. Herpes zoster oticus, which is caused by the spread of the varicella-zoster virus to facial nerves, is characterized by intense ear pain, a rash around the ear, mouth, face, neck, and scalp, and paralysis of facial nerves. Other symptoms may include hearing loss, vertigo (abnormal sensation of movement), and tinnitus (abnormal sounds). Taste loss in the tongue and dry mouth and eyes may also occur.

Wikipedia : 74 Ramsay Hunt syndrome type 2, also known as herpes zoster oticus, is a disorder that is caused by the... more...

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Related Diseases for Herpes Zoster Oticus

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Diseases related to Herpes Zoster Oticus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 147)
# Related Disease Score Top Affiliating Genes
1 ramsay hunt syndrome i 12.8
2 obsolete: ramsay hunt syndrome type ii 12.5
3 myoclonus and ataxia 12.0
4 herpes zoster 11.2
5 facial paralysis 11.0
6 chickenpox 10.8
7 myoclonus 10.7
8 ataxia and polyneuropathy, adult-onset 10.7
9 bell's palsy 10.7
10 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.6
11 myoclonic cerebellar dyssynergia 10.6
12 polyneuropathy 10.5
13 aceruloplasminemia 10.5
14 exanthem 10.4
15 neuritis 10.4
16 immune deficiency disease 10.4
17 mitochondrial encephalomyopathy 10.4
18 trigeminal neuralgia 10.4
19 acoustic neuroma 10.4
20 neuroma 10.4
21 unverricht-lundborg syndrome 10.4
22 encephalitis 10.4
23 pathologic nystagmus 10.4
24 vestibular neuronitis 10.3
25 laryngitis 10.3
26 herpes simplex 10.3
27 myoclonus epilepsy 10.3
28 migraine with or without aura 1 10.3
29 migraine without aura 10.3
30 occipital neuralgia 10.3
31 glossopharyngeal neuralgia 10.3
32 rheumatoid arthritis 10.2
33 osteonecrosis 10.2
34 lymphocytic leukemia 10.2
35 meningoencephalitis 10.2
36 aseptic meningitis 10.2
37 guillain-barre syndrome 10.2
38 labyrinthitis 10.2
39 pharyngitis 10.2
40 sensory peripheral neuropathy 10.2
41 inappropriate adh syndrome 10.2
42 progressive myoclonus epilepsy 10.2
43 47,xyy 10.2
44 sudden sensorineural hearing loss 10.2
45 hemifacial spasm, familial 10.2
46 kearns-sayre syndrome 10.2
47 branchiootic syndrome 1 10.2
48 sensorineural hearing loss 10.2
49 malignant otitis externa 10.2
50 optic neuritis 10.2

Graphical network of the top 20 diseases related to Herpes Zoster Oticus:



Diseases related to Herpes Zoster Oticus
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Symptoms & Phenotypes for Herpes Zoster Oticus

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Symptoms:

12
  • • vertigo
  • • headache
  • • tinnitus
  • • vesicular rash of the ear
  • • otalgia
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Drugs & Therapeutics for Herpes Zoster Oticus

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Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Complex Oro-Facial Pain: Functional Imaging Characterization and Treatment With Transcranial Magnetic Stimulation Completed NCT02633306

Search NIH Clinical Center for Herpes Zoster Oticus

Cochrane evidence based reviews: herpes zoster oticus

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Genetic Tests for Herpes Zoster Oticus

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Anatomical Context for Herpes Zoster Oticus

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The Foundational Model of Anatomy Ontology organs/tissues related to Herpes Zoster Oticus:

19
Facial Nerve

MalaCards organs/tissues related to Herpes Zoster Oticus:

40
Eye, Tongue, Bone, Testes, Brain, Temporal Lobe
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Publications for Herpes Zoster Oticus

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Articles related to Herpes Zoster Oticus:

(show top 50) (show all 178)
# Title Authors PMID Year
1
Atypical clinical manifestations of herpes zoster oticus: diagnostic usefulness of magnetic resonance imaging. 61
31278535 2019
2
Recovery of ocular and cervical vestibular evoked myogenic potentials after treatment of inner ear diseases. 61
31070081 2019
3
Herpes zoster oticus with meningitis masquerading as malignant otitis externa. 61
31177200 2019
4
[From the Experts office: Auricular perichondritis or herpes zoster oticus? - Diagnostic error, diagnostic mistake, or deficient examination findings?] 61
30620967 2019
5
Ramsay Hunt syndrome. 61
30637343 2018
6
Electroneurography in the acute stage of facial palsy as a predictive factor for the development of facial synkinesis sequela. 61
28966005 2018
7
Acute Facial Nerve Palsy With Ipsilateral Soft Palate Ulcers. 61
28388396 2017
8
Facial palsy and atrial fibrillation: a special case of Ramsay Hunt syndrome. 61
28705842 2017
9
Facial paralysis due to Ramsay Hunt syndrome - A rare condition. 61
28614529 2017
10
Characteristics of hearing loss in patients with herpes zoster oticus. 61
27861389 2016
11
Temporal Lobe Retraction Provides Better Surgical Exposure of the Peri-Geniculate Ganglion for Facial Nerve Decompression via Transmastoid Approach. 61
27593878 2016
12
Clinical manifestations in patients with herpes zoster oticus. 61
26308524 2016
13
[The damage to the trigeminal nerve associated with herpetic viral infection in otorhinolaryngology]. 61
27500572 2016
14
Test battery of cranial nerves VII and VIII for assessing herpes zoster oticus. 61
25385809 2015
15
Painful rash of the auricle: Herpes zoster oticus. 61
25531857 2014
16
[Three cases of Ramsay-Hunt syndrome concurrent with ipsilateral vocal cord paralysis]. 61
25007684 2014
17
Vocal cord paralysis associated with Ramsay Hunt syndrome: looking back 50 years. 61
24503657 2014
18
A case of generalized varicelliform eruption after herpes zoster oticus. 61
24335939 2014
19
Vestibular and cochlear neuritis in patients with Ramsay Hunt syndrome: a Gd-enhanced MRI study. 61
23237095 2013
20
Comparison of Transcranial Magnetic Stimulation and Electroneuronography Between Bell's Palsy and Ramsay Hunt Syndrome in Their Acute Stages. 61
23525840 2013
21
Contralateral botulinum toxin injection to improve facial asymmetry after acute facial paralysis. 61
23444480 2013
22
Characteristics of adverse effects when using high dose short term steroid regimen. 61
24653873 2012
23
Herpes zoster oticus: a clinical model for a transynaptic, reflex pathways, viral transmission hypotheses. 61
22709534 2012
24
Herpes zoster oticus (Ramsay Hunt syndrome) in children: case report and literature review. 61
22445801 2012
25
Ramsay Hunt syndrome. 61
22429645 2012
26
Ear, nose and throat lesions in hiv/aids patients in komfo anokye teaching hospital, kumasi, ghana. 61
25452982 2012
27
[Case of atypical Ramsay-Hunt syndrome who presented with severe vertigo and vomiting]. 61
22352034 2012
28
Mirror biofeedback rehabilitation after administration of single-dose botulinum toxin for treatment of facial synkinesis. 61
21965443 2012
29
Prognostic factors in herpes zoster oticus (ramsay hunt syndrome). 61
21725270 2011
30
[Herpes zoster oticus with cranial nerve affection]. 61
20961509 2010
31
Benign paroxysmal positional vertigo secondary to inner ear disease. 61
20723780 2010
32
Herpes zoster oticus: A rare clinical entity. 61
22114399 2010
33
The management of peripheral facial nerve palsy: "paresis" versus "paralysis" and sources of ambiguity in study designs. 61
20009779 2010
34
[Herpes zoster oticus-associated jugular foramen syndrome]. 61
20112795 2010
35
Correlation between enhanced MRI and surgical findings in herpes zoster oticus. 61
18836966 2009
36
Herpes zoster oticus associated with varicella zoster virus encephalitis. 61
19213041 2009
37
Seventh cranial neuropathy. 61
19214928 2009
38
Cutaneous electrical stimulation treatment in unresolved facial nerve paralysis: an exploratory study. 61
18787496 2008
39
Antiviral therapy for Ramsay Hunt syndrome (herpes zoster oticus with facial palsy) in adults. 61
18843734 2008
40
Corticosteroids as adjuvant to antiviral treatment in Ramsay Hunt syndrome (herpes zoster oticus with facial palsy) in adults. 61
18646170 2008
41
Ramsay hunt syndrome in a person with HIV disease. 61
23120531 2008
42
Statistical analysis of pure tone audiometry and caloric test in herpes zoster oticus. 61
19434256 2008
43
Transient facial palsy in two cases of benign, very rare middle ear tumors (carcinoid tumor and myxoma). 61
18195660 2008
44
Do antiviral agents effectively treat Ramsay Hunt syndrome? 61
19151685 2008
45
Herpes zoster laryngitis: case report and serological profile. 61
17124598 2007
46
Infective causes of facial nerve paralysis. 61
17031324 2007
47
An extremely unusual presentation of varicella zoster viral infection of cranial nerves mimicking Garcin syndrome. 61
16226370 2006
48
Prognostic value of electroneurography in Bell's palsy and Ramsay-Hunt's syndrome. 61
16620335 2006
49
Characteristics and clinical applications of vestibular-evoked myogenic potentials. 61
15911791 2005
50
Postoperative Ramsay-Hunt syndrome after acoustic neuroma resection. Viral reactivation. 61
16001695 2005
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Variations for Herpes Zoster Oticus

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Expression for Herpes Zoster Oticus

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Search GEO for disease gene expression data for Herpes Zoster Oticus.
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Pathways for Herpes Zoster Oticus

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GO Terms for Herpes Zoster Oticus

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Sources for Herpes Zoster Oticus

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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