MCID: HRP026
MIFTS: 19

Herpetiform Pemphigus

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Herpetiform Pemphigus

MalaCards integrated aliases for Herpetiform Pemphigus:

Name: Herpetiform Pemphigus 58

Classifications:

Orphanet: 58  
Rare skin diseases


External Ids:

ICD10 via Orphanet 33 L10.8
Orphanet 58 ORPHA208524

Summaries for Herpetiform Pemphigus

MalaCards based summary : Herpetiform Pemphigus is related to pemphigus and pemphigus foliaceus. An important gene associated with Herpetiform Pemphigus is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Keratinization and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin.

Related Diseases for Herpetiform Pemphigus

Diseases related to Herpetiform Pemphigus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 pemphigus 30.3 DST DSG3 DSG1
2 pemphigus foliaceus 29.9 DST DSG3 DSG1
3 pemphigus vulgaris, familial 29.6 DST DSG3 DSG1
4 bullous pemphigoid 29.6 DST DSG3 DSG1
5 paraneoplastic pemphigus 29.2 DST DSG3 DSG1
6 dermatitis herpetiformis, familial 10.2
7 pemphigoid 10.2
8 dermatitis herpetiformis 10.2
9 annular erythema 10.0
10 esophageal cancer 10.0
11 systemic lupus erythematosus 10.0
12 anemia, autoimmune hemolytic 10.0
13 exanthem 10.0
14 pustulosis of palm and sole 10.0
15 hemolytic anemia 10.0
16 psoriasis 10.0
17 hypereosinophilic syndrome 10.0
18 ecthyma 9.8 DST DSG1
19 acute laryngopharyngitis 9.8 DST DSG1
20 tinea imbricata 9.7 DSG3 DSG1
21 bullous impetigo 9.7 DSG3 DSG1
22 impetigo 9.7 DSG3 DSG1
23 pseudomembranous conjunctivitis 9.7 DSG3 DSG1
24 iga pemphigus 9.7 DSG3 DSG1
25 ritter's disease 9.6 DSG3 DSG1
26 naxos disease 9.6 DSG3 DSG1
27 benign chronic pemphigus 9.6 DSG3 DSG1
28 pyoderma 9.5 DSG3 DSG1
29 pemphigoid gestationis 9.5 DST DSG3 DSG1
30 subcorneal pustular dermatosis 9.5 DST DSG3 DSG1
31 lichen disease 9.5 DST DSG3 DSG1
32 bullous skin disease 9.5 DST DSG3 DSG1
33 skin disease 9.5 DST DSG3 DSG1
34 autoimmune disease of skin and connective tissue 9.5 DST DSG3 DSG1
35 lichen planus 9.5 DST DSG3 DSG1
36 autoimmune disease of musculoskeletal system 9.5 DST DSG3 DSG1
37 integumentary system disease 9.4 DST DSG3 DSG1
38 familial woolly hair syndrome 9.4 DSG3 DSG1

Graphical network of the top 20 diseases related to Herpetiform Pemphigus:



Diseases related to Herpetiform Pemphigus

Symptoms & Phenotypes for Herpetiform Pemphigus

Drugs & Therapeutics for Herpetiform Pemphigus

Search Clinical Trials , NIH Clinical Center for Herpetiform Pemphigus

Genetic Tests for Herpetiform Pemphigus

Anatomical Context for Herpetiform Pemphigus

MalaCards organs/tissues related to Herpetiform Pemphigus:

40
Skin

Publications for Herpetiform Pemphigus

Articles related to Herpetiform Pemphigus:

(show all 37)
# Title Authors PMID Year
1
Antibody reactive to a novel autoantigen on the nondesmosomal keratinocyte surfaces leads to herpetiform pemphigus. 61
30604537 2019
2
Herpetiform pemphigus with characteristic transmission electron microscopic findings of various-sized ballooning vacuoles in keratinocytes without acantholysis. 61
29573413 2019
3
Concurrence of bullous pemphigoid and herpetiform pemphigus with IgG antibodies to desmogleins 1/3 and desmocollins 1-3. 61
22924466 2013
4
Herpetiform pemphigus with anti-Dsg 1 and full-length BP180 autoantibodies. 61
22265805 2012
5
Herpetiform pemphigus without anti-desmoglein 1/3 autoantibodies. 61
20507392 2010
6
Herpetiform pemphigus clinically resembling bullous pemphigoid. 61
19882023 2008
7
[Herpetiform pemphigus associated with esophageal carcinoma]. 61
16476349 2005
8
A case of herpetiform pemphigus with anti-desmoglein 3 IgG autoantibodies. 61
15187309 2004
9
IgG/IgA pemphigus with IgG and IgA antidesmoglein 1 antibodies detected by enzyme-linked immunosorbent assay. 61
12410717 2002
10
Bullous pemphigoid sera react specifically with various domains of BP230, most frequently with C-terminal domain, by immunoblot analyses using bacterial recombinant proteins covering the entire molecule. 61
11493314 2001
11
[Herpetiform pemphigus]. 61
11269073 2000
12
Late development of antidesmoglein 1 antibodies in pemphigus vulgaris: correlation with disease progression. 61
10606856 1999
13
A case of herpetiform pemphigus coexisting with psoriasis vulgaris. 61
10583136 1999
14
Desmoglein 1 and desmoglein 3 are the target autoantigens in herpetiform pemphigus. 61
10456343 1999
15
Autoimmunity against desmosomal cadherins in pemphigus. 61
10379702 1999
16
Herpetiform pemphigus. 61
10188168 1999
17
Simultaneous occurrence of herpetiform pemphigus and endemic pemphigus foliaceus (fogo selvagem). 61
9427079 1997
18
Herpetiform pemphigus showing reactivity with pemphigus vulgaris antigen (desmoglein 3) 61
9274636 1997
19
[Case report of herpetiform pemphigus]. 61
9229963 1996
20
A case of herpetiform pemphigus associated with autoimmune hemolytic anemia: detection of autoantibodies against multiple epidermal antigens. 61
8829509 1996
21
Childhood herpetiform pemphigus responsive to co-trimoxazole. 61
20952950 1995
22
A case of herpetiform pemphigus associated with lung cancer. 61
7962962 1994
23
Thiopronine-induced herpetiform pemphigus: report of a case studied by immunoelectron microscopy and immunoblot analysis. 61
8123578 1994
24
IgA pemphigus foliaceus with a clinical presentation of pemphigus herpetiformis. 61
1646833 1991
25
The clinical and histopathological spectrum of IgA-pemphigus--report of two cases. 61
2279341 1990
26
[Pemphigus herpetiformis--the value of simple diagnostic measures]. 61
2683437 1989
27
[Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8]. 61
2972666 1988
28
Herpetiform Pemphigus. 61
28134147 1988
29
[Autoimmune pemphigus combined with alpha 1-antitrypsin deficiency]. 61
3069024 1988
30
[Pemphigus herpetiformis]. 61
6396987 1984
31
Bullous eruption of systemic lupus erythematosus: "herpetiform pemphigus". 61
6350380 1983
32
Herpetiform pemphigus-like skin lesions induced by D-penicillamine. 61
7026638 1980
33
[Pemphigus and pemphigoid]. 61
6987108 1980
34
Herpetiform pemphigus induced by penicillamine. 61
588456 1977
35
[Mixed bullous diseases]. 61
767303 1976
36
Herpetiform pemphigus, a variable pattern of pemphigus. 61
1097347 1975
37
Herpetiform pemphigus foliaceus responsive to dapsone. 61
5060427 1972

Variations for Herpetiform Pemphigus

Expression for Herpetiform Pemphigus

Search GEO for disease gene expression data for Herpetiform Pemphigus.

Pathways for Herpetiform Pemphigus

Pathways related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 DSG3 DSG1
2
Show member pathways
10.69 DSG3 DSG1

GO Terms for Herpetiform Pemphigus

Cellular components related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.33 DST DSG3 DSG1
2 cell-cell junction GO:0005911 9.26 DSG3 DSG1
3 cornified envelope GO:0001533 8.96 DSG3 DSG1
4 desmosome GO:0030057 8.62 DSG3 DSG1

Biological processes related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.32 DSG3 DSG1
2 cell-cell adhesion GO:0098609 9.26 DSG3 DSG1
3 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.16 DSG3 DSG1
4 cornification GO:0070268 8.96 DSG3 DSG1
5 cell adhesion GO:0007155 8.8 DST DSG3 DSG1

Molecular functions related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 8.8 DST DSG3 DSG1

Sources for Herpetiform Pemphigus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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