MCID: HRP026
MIFTS: 21

Herpetiform Pemphigus

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Herpetiform Pemphigus

MalaCards integrated aliases for Herpetiform Pemphigus:

Name: Herpetiform Pemphigus 60

Classifications:

Orphanet: 60  
Rare skin diseases


External Ids:

ICD10 via Orphanet 35 L10.2
Orphanet 60 ORPHA208524

Summaries for Herpetiform Pemphigus

MalaCards based summary : Herpetiform Pemphigus is related to pemphigus and pemphigus foliaceus. An important gene associated with Herpetiform Pemphigus is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Keratinization and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin and lung.

Related Diseases for Herpetiform Pemphigus

Diseases related to Herpetiform Pemphigus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 pemphigus 30.3 DSG1 DSG3 DST
2 pemphigus foliaceus 29.5 DSG1 DSG3 DST
3 bullous pemphigoid 29.4 DSG1 DSG3 DST
4 pemphigus vulgaris 29.2 DSG1 DSG3 DST
5 pemphigus vulgaris, familial 10.1
6 anemia, autoimmune hemolytic 10.1
7 lung cancer 10.1
8 psoriasis 7 10.1
9 psoriasis 11 10.1
10 psoriasis 13 10.1
11 hemolytic anemia 10.1
12 psoriasis 10.1
13 autoimmune disease of skin and connective tissue 9.8 DSG1 DST
14 lichen disease 9.7 DSG1 DST
15 bullous impetigo 9.7 DSG1 DSG3
16 lichen planus 9.5 DSG3 DST
17 bullous skin disease 9.5 DSG1 DSG3 DST
18 skin disease 9.4 DSG1 DSG3 DST
19 cellulitis 9.4 DSG1 DSG3 DST
20 subcorneal pustular dermatosis 9.4 DSG1 DSG3 DST
21 paraneoplastic pemphigus 9.4 DSG1 DSG3 DST

Graphical network of the top 20 diseases related to Herpetiform Pemphigus:



Diseases related to Herpetiform Pemphigus

Symptoms & Phenotypes for Herpetiform Pemphigus

Drugs & Therapeutics for Herpetiform Pemphigus

Search Clinical Trials , NIH Clinical Center for Herpetiform Pemphigus

Genetic Tests for Herpetiform Pemphigus

Anatomical Context for Herpetiform Pemphigus

MalaCards organs/tissues related to Herpetiform Pemphigus:

42
Skin, Lung

Publications for Herpetiform Pemphigus

Articles related to Herpetiform Pemphigus:

(show all 22)
# Title Authors Year
1
Antibody reactive to a novel autoantigen on the nondesmosomal keratinocyte surfaces leads to herpetiform pemphigus. ( 30604537 )
2019
2
Herpetiform pemphigus with characteristic transmission electron microscopic findings of various-sized ballooning vacuoles in keratinocytes without acantholysis. ( 29573413 )
2018
3
Concurrence of bullous pemphigoid and herpetiform pemphigus with IgG antibodies to desmogleins 1/3 and desmocollins 1-3. ( 22924466 )
2013
4
Herpetiform pemphigus with anti-Dsg 1 and full-length BP180 autoantibodies. ( 22265805 )
2012
5
Herpetiform pemphigus without anti-desmoglein 1/3 autoantibodies. ( 20507392 )
2010
6
Herpetiform pemphigus clinically resembling bullous pemphigoid. ( 19882023 )
2008
7
A case of herpetiform pemphigus with anti-desmoglein 3 IgG autoantibodies. ( 15187309 )
2004
8
Desmoglein 1 and desmoglein 3 are the target autoantigens in herpetiform pemphigus. ( 10456343 )
1999
9
Herpetiform pemphigus. ( 10188168 )
1999
10
A case of herpetiform pemphigus coexisting with psoriasis vulgaris. ( 10583136 )
1999
11
Simultaneous occurrence of herpetiform pemphigus and endemic pemphigus foliaceus (fogo selvagem). ( 9427079 )
1997
12
Herpetiform pemphigus showing reactivity with pemphigus vulgaris antigen (desmoglein 3) ( 9274636 )
1997
13
A case of herpetiform pemphigus associated with autoimmune hemolytic anemia: detection of autoantibodies against multiple epidermal antigens. ( 8829509 )
1996
14
Childhood herpetiform pemphigus responsive to co-trimoxazole. ( 20952950 )
1995
15
Thiopronine-induced herpetiform pemphigus: report of a case studied by immunoelectron microscopy and immunoblot analysis. ( 8123578 )
1994
16
A case of herpetiform pemphigus associated with lung cancer. ( 7962962 )
1994
17
Herpetiform Pemphigus. ( 28134147 )
1988
18
Bullous eruption of systemic lupus erythematosus: "herpetiform pemphigus". ( 6350380 )
1983
19
Herpetiform pemphigus-like skin lesions induced by D-penicillamine. ( 7026638 )
1980
20
Herpetiform pemphigus induced by penicillamine. ( 588456 )
1977
21
Herpetiform pemphigus, a variable pattern of pemphigus. ( 1097347 )
1975
22
Herpetiform pemphigus foliaceus responsive to dapsone. ( 5060427 )
1972

Variations for Herpetiform Pemphigus

Expression for Herpetiform Pemphigus

Search GEO for disease gene expression data for Herpetiform Pemphigus.

Pathways for Herpetiform Pemphigus

Pathways related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 DSG1 DSG3
2
Show member pathways
10.69 DSG1 DSG3

GO Terms for Herpetiform Pemphigus

Cellular components related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.33 DSG1 DSG3 DST
2 cornified envelope GO:0001533 8.96 DSG1 DSG3
3 desmosome GO:0030057 8.62 DSG1 DSG3

Biological processes related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 DSG1 DSG3
2 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.16 DSG1 DSG3
3 cornification GO:0070268 8.96 DSG1 DSG3
4 cell adhesion GO:0007155 8.8 DSG1 DSG3 DST

Molecular functions related to Herpetiform Pemphigus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 8.8 DSG1 DSG3 DST

Sources for Herpetiform Pemphigus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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