MCID: HTR001
MIFTS: 26

Heterophyiasis

Categories: Cardiovascular diseases, Gastrointestinal diseases, Infectious diseases, Neuronal diseases

Aliases & Classifications for Heterophyiasis

MalaCards integrated aliases for Heterophyiasis:

Name: Heterophyiasis 12 3 15
Heterophyes Infectious Disease 12

Classifications:



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Disease Ontology 12 DOID:882
ICD9CM 34 121.6
NCIt 50 C128389
SNOMED-CT 67 22905009
ICD10 32 B66.8
UMLS 70 C0152071

Summaries for Heterophyiasis

CDC : 3 Adults release embryonated eggs each with a fully-developed miracidium, and eggs are passed in the host's fecesThe number 1 . After ingestion by a suitable snail (first intermediate host), the eggs hatch and release miracidia which penetrate the snail's intestineThe number 2. Genera Cerithidia and Pironella are important snail hosts in Asia and the Middle East respectively. The miracidia undergo several developmental stages in the snail, i.e. sporocystsThe number 2a, rediaeThe number 2b, and cercariaeThe number 2c. Many cercariae are produced from each redia. The cercariae are released from the snailThe number 3 and encyst as metacercariae in the tissues of a suitable fresh/brackish water fish (second intermediate host)The number 4. The definitive host becomes infected by ingesting undercooked or salted fish containing metacercariaeThe number 5. After ingestion, the metacercariae excyst, attach to the mucosa of the small intestineThe number 6 and mature into adults (measuring 1.0 to 1.7 mm by 0.3 to 0.4 mm)The number 7. In addition to humans, various fish-eating mammals (e.g., cats and dogs) and birds can be infected by Heterophyes heterophyes The number 8.

MalaCards based summary : Heterophyiasis, also known as heterophyes infectious disease, is related to toxicodendron dermatitis and actinic prurigo. An important gene associated with Heterophyiasis is SELE (Selectin E), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and TNF signaling pathway.

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves intestinal infection by the parasite of the genus Heterophyes. The symptoms are diarrhea and colicky abdominal pain. Migration of the eggs to the heart, results in fatal myocardial and valvular damage. Brain can also be infected.

Related Diseases for Heterophyiasis

Diseases related to Heterophyiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
# Related Disease Score Top Affiliating Genes
1 toxicodendron dermatitis 10.1 SELE ICAM1
2 actinic prurigo 10.1 SELE ICAM1
3 inflammatory and toxic neuropathy 10.1 SELE ALB
4 rheumatoid vasculitis 10.1 SELE ICAM1
5 shwartzman phenomenon 10.1 SELE ICAM1
6 plummer's disease 10.1 SELE ICAM1
7 sympathetic ophthalmia 10.1 SELE ICAM1
8 hydrocele 10.1 SELE ICAM1
9 leukostasis 10.1 SELE ICAM1
10 severe nonproliferative diabetic retinopathy 10.1 ICAM1 ALB
11 plasmodium vivax malaria 10.1 SELE ICAM1
12 erythema nodosum 10.1 SELE ICAM1
13 background diabetic retinopathy 10.1 ICAM1 ALB
14 parametritis 10.1 ICAM1 ALB
15 crescentic glomerulonephritis 10.1 SELE ICAM1
16 arthus reaction 10.1 ICAM1 ALB
17 plague 10.1 SELE ALB
18 cutaneous lupus erythematosus 10.1 SELE ICAM1
19 rapidly progressive glomerulonephritis 10.1 ICAM1 ALB
20 methotrexate toxicity 10.1 SELE GPT
21 immune-complex glomerulonephritis 10.1 ICAM1 ALB
22 henoch-schoenlein purpura 10.1 ICAM1 ALB
23 macular retinal edema 10.1 ICAM1 ALB
24 amebiasis 10.1 ICAM1 ALB
25 african tick-bite fever 10.1 SELE GPT
26 carotid stenosis 10.1 SELE ICAM1
27 guillain-barre syndrome 10.1 ICAM1 ALB
28 dipetalonemiasis 10.1 GPT ALB
29 rheumatic fever 10.1 ICAM1 ALB
30 afferent loop syndrome 10.0 GPT ALB
31 ankylosing spondylitis 1 10.0 GPT ALB
32 acalculous cholecystitis 10.0 GPT ALB
33 cholecystitis 10.0 GPT ALB
34 hepatic infarction 10.0 GPT ALB
35 hydrops of gallbladder 10.0 GPT ALB
36 splenic abscess 10.0 GPT ALB
37 ascending cholangitis 10.0 GPT ALB
38 gastrointestinal tuberculosis 10.0 GPT ALB
39 limb ischemia 10.0 SELE ICAM1
40 granulomatous hepatitis 10.0 GPT ALB
41 common cold 10.0 ICAM1 ALB
42 paralytic ileus 10.0 GPT ALB
43 acute cholangitis 10.0 GPT ALB
44 common bile duct disease 10.0 GPT ALB
45 coronary aneurysm 10.0 GPT ALB
46 hepatic coma 10.0 GPT ALB
47 abdominal tuberculosis 10.0 GPT ALB
48 bile duct cysts 10.0 GPT ALB
49 heart aneurysm 10.0 GPT ALB
50 splenic infarction 10.0 GPT ALB

Graphical network of the top 20 diseases related to Heterophyiasis:



Diseases related to Heterophyiasis

Symptoms & Phenotypes for Heterophyiasis

Drugs & Therapeutics for Heterophyiasis

Search Clinical Trials , NIH Clinical Center for Heterophyiasis

Genetic Tests for Heterophyiasis

Anatomical Context for Heterophyiasis

Publications for Heterophyiasis

Articles related to Heterophyiasis:

(show all 23)
# Title Authors PMID Year
1
Proteomic analysis of Ascocotyle longa (Trematoda: Heterophyidae) metacercariae. 61
32745491 2020
2
HISTOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDIES IN EXPERIMENTAL HETEROPHYIASIS AND THE ROLE OF PRAZIQUANTEL AND AMINOGUANIDINE. 61
30157335 2017
3
The genus Pirenella Gray, 1847 (= Cerithideopsilla Thiele, 1929) (Gastropoda: Potamididae) in the Indo-West Pacific region and Mediterranean Sea. 61
27395955 2016
4
Insights into regulatory molecules of intestinal epithelial cell turnover during experimental infection by Heterophyes heterophyes. 61
24852217 2014
5
ELISA and some biochemical tests of heterophyidae infection in laboratory animals. 61
21779862 2012
6
Role of parasites among chronic diarrheic patients. 61
21268537 2010
7
Mirazid in treatment of three zoonotic trematodes in Beni-Sweif and Dakhalia Governorates. 61
20503592 2010
8
The life cycle of Ascocotyle (Phagicola) longa (Digenea: Heterophyidae), a causative agent of fish-borne trematodosis. 61
19896920 2010
9
Mirazid (Commiphora molmol) in treatment of human heterophyiasis. 61
17985576 2007
10
Treatment of experimental heterophyiasis with two plant extracts, areca nut and pumpkin seed. 61
12214927 2002
11
Study of soluble adhesion molecules in some intestinal and tissue helminthes. 61
11478449 2001
12
Epidemiological study of heterophyiasis among humans in an area of Egypt. 61
12197351 2000
13
[Heterophyiasis and diarrhea after travel: a case report of a child returning from a trip to Egypt]. 61
8559020 1995
14
Specificity of crude and purified Fasciola antigens in immunodiagnosis of human fascioliasis. 61
1692074 1990
15
Cross-reactions in immunodiagnosis of patients infected with Schistosoma, Fasciola and Heterophyes using ELISA. 61
2507655 1989
16
Serum and intestinal immunoglobulins in heterophyiasis. 61
2708855 1989
17
The cure rates of patients infected with heterophyiasis and treated with praziquantel versus niclosamide. 61
3418143 1988
18
Sero immunological diagnosis of heterophyiasis. 61
3320218 1987
19
Human infections by Heterophyes heterophyes and H. dispar imported from Saudi Arabia. 61
12886112 1986
20
Investigations on the prevalence of Heterophyes species in twelve populations of the first intermediate host in Egypt and Sudan. 61
4087327 1985
21
Histochemical studies in experimental heterophyiasis. 61
4056462 1985
22
Pirenella conica and heterophyiasis in one of the beaches of Matrouh, Egypt. 61
6736704 1984
23
Praziquantil in treatment of heterophyiasis (a preliminary study) 61
6663122 1983

Variations for Heterophyiasis

Expression for Heterophyiasis

Search GEO for disease gene expression data for Heterophyiasis.

Pathways for Heterophyiasis

Pathways related to Heterophyiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.32 SELE ICAM1
2 11.18 SELE ICAM1 CASP3
3
Show member pathways
11.17 SELE ICAM1
4 11.02 SELE ICAM1
5 10.91 SELE ICAM1
6 10.8 SELE ICAM1 CASP3
7 10.72 SELE ICAM1

GO Terms for Heterophyiasis

Cellular components related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 8.8 SELE ICAM1 CASP3

Biological processes related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.37 SELE ICAM1
2 response to tumor necrosis factor GO:0034612 9.32 SELE CASP3
3 response to amino acid GO:0043200 9.26 ICAM1 CASP3
4 cellular response to organic substance GO:0071310 9.16 ICAM1 CASP3
5 leukocyte cell-cell adhesion GO:0007159 8.96 SELE ICAM1
6 response to lipopolysaccharide GO:0032496 8.8 SELE ICAM1 CASP3

Molecular functions related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pyridoxal phosphate binding GO:0030170 8.62 GPT ALB

Sources for Heterophyiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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