MCID: HTR001
MIFTS: 32

Heterophyiasis

Categories: Infectious diseases

Aliases & Classifications for Heterophyiasis

MalaCards integrated aliases for Heterophyiasis:

Name: Heterophyiasis 12 3 15
Heterophyes Infectious Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:882
ICD10 33 B66.8
ICD9CM 35 121.6
SNOMED-CT 68 187126008 22905009
UMLS 73 C0152071

Summaries for Heterophyiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves intestinal infection by the parasite of the genus Heterophyes. The symptoms are diarrhea and colicky abdominal pain. Migration of the eggs to the heart, results in fatal myocardial and valvular damage. Brain can also be infected.

MalaCards based summary : Heterophyiasis, also known as heterophyes infectious disease, is related to lymphocytic vasculitis and african tick-bite fever. An important gene associated with Heterophyiasis is SELE (Selectin E), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and NF-kappa B signaling pathway. Affiliated tissues include heart and brain, and related phenotypes are cellular and hematopoietic system

CDC : 3 DPDx is an education resource designed for health professionals and laboratory scientists. For an overview including prevention and control visit www.cdc.gov/parasites/.

Related Diseases for Heterophyiasis

Diseases related to Heterophyiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 201)
# Related Disease Score Top Affiliating Genes
1 lymphocytic vasculitis 10.5 ICAM1 SELE
2 african tick-bite fever 10.4 CD40LG SELE
3 mooren's ulcer 10.4 ICAM1 SELE
4 plummer's disease 10.4 ICAM1 SELE
5 subendocardial myocardial infarction 10.4 ICAM1 SELE
6 actinic prurigo 10.4 ICAM1 SELE
7 endophthalmitis 10.4 ICAM1 SELE
8 rheumatoid vasculitis 10.4 ICAM1 SELE
9 leukostasis 10.4 ICAM1 SELE
10 shwartzman phenomenon 10.4 ICAM1 SELE
11 legg-calve-perthes disease 10.4 CD40LG SELE
12 cytomegalovirus infection 10.4 ICAM1 SELE
13 allergic contact dermatitis 10.2 ICAM1 SELE
14 dengue disease 10.2 CD40LG ICAM1
15 autoinflammation, lipodystrophy, and dermatosis syndrome 10.2 ICAM1 SELE
16 contact dermatitis 10.2 ICAM1 SELE
17 takayasu arteritis 10.2 CD40LG SELE
18 ehrlichiosis 10.2 CASP3 CD40LG
19 plasmodium falciparum malaria 10.1 ICAM1 SELE
20 idiopathic neutropenia 10.1 CASP3 CD40LG
21 synovitis 10.1 ICAM1 SELE
22 oral lichen planus 10.1 CASP3 ICAM1
23 arteries, anomalies of 10.1 ICAM1 SELE
24 lymphadenitis 10.0 CASP3 ICAM1
25 selective igg deficiency disease 10.0 CD40LG CD79A
26 c1q nephropathy 10.0 CD40LG CD79A
27 meningovascular neurosyphilis 10.0 CD40LG CD79A
28 alpha chain disease 10.0 CD40LG CD79A
29 brill-zinsser disease 10.0 CD40LG CD79A
30 exudative glomerulonephritis 10.0 CD40LG CD79A
31 cork-handlers' disease 10.0 CD40LG CD79A
32 salpingo-oophoritis 10.0 CD40LG CD79A
33 early yaws 10.0 CD40LG CD79A
34 ventilation pneumonitis 10.0 CD40LG CD79A
35 chronic interstitial cystitis 10.0 CD40LG CD79A
36 axillary adenitis 10.0 CD40LG CD79A
37 cryofibrinogenemia 10.0 CD40LG CD79A
38 trichostrongyloidiasis 10.0 CD40LG CD79A
39 subacute bacterial endocarditis 10.0 CD40LG CD79A
40 immunoglobulin g deficiency 10.0 CD40LG CD79A
41 orbital granuloma 10.0 CD40LG CD79A
42 transient hypogammaglobulinemia of infancy 10.0 CD40LG CD79A
43 hyperglobulinemic purpura 10.0 CD40LG CD79A
44 gastroduodenitis 10.0 CD40LG CD79A
45 bacterial conjunctivitis 10.0 CD40LG CD79A
46 heavy chain disease 10.0 CD40LG CD79A
47 ophthalmia neonatorum 10.0 CD40LG CD79A
48 immunoglobulin a deficiency 1 10.0 CD40LG CD79A
49 parotid disease 10.0 CD40LG CD79A
50 cerebral arteritis 10.0 CD40LG CD79A

Graphical network of the top 20 diseases related to Heterophyiasis:



Diseases related to Heterophyiasis

Symptoms & Phenotypes for Heterophyiasis

MGI Mouse Phenotypes related to Heterophyiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.65 SELE CASP3 CD40LG CD79A ICAM1
2 hematopoietic system MP:0005397 9.55 CASP3 CD40LG CD79A ICAM1 SELE
3 immune system MP:0005387 9.35 SELE CASP3 CD40LG CD79A ICAM1
4 integument MP:0010771 8.92 SELE CASP3 CD40LG ICAM1

Drugs & Therapeutics for Heterophyiasis

Search Clinical Trials , NIH Clinical Center for Heterophyiasis

Genetic Tests for Heterophyiasis

Anatomical Context for Heterophyiasis

MalaCards organs/tissues related to Heterophyiasis:

41
Heart, Brain

Publications for Heterophyiasis

Articles related to Heterophyiasis:

# Title Authors Year
1
Mirazid (Commiphora molmol) in treatment of human heterophyiasis. ( 17985576 )
2007
2
Treatment of experimental heterophyiasis with two plant extracts, areca nut and pumpkin seed. ( 12214927 )
2002
3
Epidemiological study of heterophyiasis among humans in an area of Egypt. ( 12197351 )
2000
4
Serum and intestinal immunoglobulins in heterophyiasis. ( 2708855 )
1989
5
The cure rates of patients infected with heterophyiasis and treated with praziquantel versus niclosamide. ( 3418143 )
1988
6
Sero immunological diagnosis of heterophyiasis. ( 3320218 )
1987
7
Histochemical studies in experimental heterophyiasis. ( 4056462 )
1985
8
Pirenella conica and heterophyiasis in one of the beaches of Matrouh, Egypt. ( 6736704 )
1984
9
Praziquantil in treatment of heterophyiasis (a preliminary study) ( 6663122 )
1983

Variations for Heterophyiasis

Expression for Heterophyiasis

Search GEO for disease gene expression data for Heterophyiasis.

Pathways for Heterophyiasis

GO Terms for Heterophyiasis

Cellular components related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.46 CD40LG CD79A ICAM1 SELE
2 external side of plasma membrane GO:0009897 9.13 CD40LG CD79A ICAM1
3 membrane raft GO:0045121 8.92 CASP3 CD79A ICAM1 SELE

Biological processes related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 9.43 CD40LG CD79A
2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.4 ICAM1 SELE
3 cellular response to organic substance GO:0071310 9.37 CASP3 ICAM1
4 response to amino acid GO:0043200 9.32 CASP3 ICAM1
5 B cell proliferation GO:0042100 9.26 CD40LG CD79A
6 response to tumor necrosis factor GO:0034612 9.16 CASP3 SELE
7 response to lipopolysaccharide GO:0032496 9.13 CASP3 ICAM1 SELE
8 leukocyte cell-cell adhesion GO:0007159 8.8 CD40LG ICAM1 SELE

Molecular functions related to Heterophyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.8 CD79A ICAM1 SELE

Sources for Heterophyiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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