MCID: HHV001
MIFTS: 18

Hhv-6 Encephalitis

Categories: Blood diseases, Rare diseases

Aliases & Classifications for Hhv-6 Encephalitis

MalaCards integrated aliases for Hhv-6 Encephalitis:

Name: Hhv-6 Encephalitis 52
Human Herpesvirus 6 Encephalitis 52 71
Variant a or Hhv-6a 52
Variant B or Hhv-6b 52

Classifications:



External Ids:

UMLS 71 C1955629

Summaries for Hhv-6 Encephalitis

NIH Rare Diseases : 52 HHV-6 encephalitis refers to inflammation of the brain due to an infection with human herpesvirus 6. People who have undergone allogeneic hematopoietic cell transplantation are at an increased risk for developing HHV-6 encephalitis, particularly when umbilical cord blood stem cells are used. People with immune system disorders may also be at an increased risk for developing this infection. Signs and symptoms vary, but often include confusion, anterograde amnesia (difficulty learning new information following the onset of amnesia), short-term memory loss, and seizures . Diagnosis often involves lumbar puncture , virus testing, and MRI . EEG 's may also be recommended when seizures are suspected. HHV-6 encephalitis is treated with an antiviral agent with activity against HHV-6. Long term outlook (chance of full recovery) can vary considerably depending individual patient factors.

MalaCards based summary : Hhv-6 Encephalitis, also known as human herpesvirus 6 encephalitis, is related to encephalitis and meningoencephalitis. Affiliated tissues include brain, testes and t cells.

Related Diseases for Hhv-6 Encephalitis

Graphical network of the top 20 diseases related to Hhv-6 Encephalitis:



Diseases related to Hhv-6 Encephalitis

Symptoms & Phenotypes for Hhv-6 Encephalitis

Drugs & Therapeutics for Hhv-6 Encephalitis

Search Clinical Trials , NIH Clinical Center for Hhv-6 Encephalitis

Genetic Tests for Hhv-6 Encephalitis

Anatomical Context for Hhv-6 Encephalitis

MalaCards organs/tissues related to Hhv-6 Encephalitis:

40
Brain, Testes, T Cells, Bone, Bone Marrow, Lung, Myeloid

Publications for Hhv-6 Encephalitis

Articles related to Hhv-6 Encephalitis:

(show top 50) (show all 109)
# Title Authors PMID Year
1
Posterior reversible encephalopathy syndrome concurrent with human herpesvirus-6B encephalitis after allogeneic hematopoietic stem cell transplantation. 61
31421950 2020
2
A Systematic Review of Sodium Disorders in HHV-6 Encephalitis. 61
32028025 2020
3
Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation. 61
31467131 2019
4
Human herpesvirus 6, 7, and 8 in solid organ transplantation: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. 61
30844089 2019
5
Long-term Outcomes of Patients With Human Herpesvirus 6 Encephalitis. 61
31334297 2019
6
Human herpesvirus 6 encephalitis in patients administered mycophenolate mofetil as prophylaxis for graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. 61
30414316 2019
7
Unexpected High Incidence of Human Herpesvirus-6 Encephalitis after Naive T Cell-Depleted Graft of Haploidentical Stem Cell Transplantation in Pediatric Patients. 61
30031939 2018
8
Clinical Significance of Human Herpesvirus 6 Positivity on the FilmArray Meningitis/Encephalitis Panel. 61
29635334 2018
9
Human Herpesvirus 6 encephalitis in an immunocompetent pregnant patient and review of the literature. 61
29902636 2018
10
Effects of Prophylactic Foscarnet on Human Herpesvirus-6 Reactivation and Encephalitis in Cord Blood Transplant Recipients: A Prospective Multicenter Trial with an Historical Control Group. 61
29454651 2018
11
Human herpesvirus-6 encephalitis following chemotherapy induction for acute myelogenous leukemia. 61
28746781 2017
12
Successful treatment and FDG-PET/CT monitoring of HHV-6 encephalitis in a non-neutropenic patient: case report and literature review. 61
28822107 2017
13
Clinical characteristics and outcome of human herpesvirus-6 encephalitis after allogeneic hematopoietic stem cell transplantation. 61
28783148 2017
14
Hyponatremia associated with human herpesvirus-6 (HHV-6) encephalitis after allogeneic hematopoietic stem cell transplantation: A presentation different from HHV-6 myelitis. 61
28501929 2017
15
Risk factors of human herpesvirus 6 encephalitis/myelitis after allogeneic hematopoietic stem cell transplantation. 61
28207973 2017
16
Human herpes virus-6 encephalitis causing severe anterograde amnesia associated with rituximab, azathioprine and prednisolone combination therapy for dermatomyositis. 61
28224486 2017
17
Human herpesvirus 6 encephalitis followed by acute disseminated encephalomyelitis in an immunocompetent adult. 61
28367948 2017
18
Viral load and ganciclovir (GCV) concentration in cerebrospinal fluid of patients successfully treated with GCV or valGCV for human herpesvirus 6 encephalitis/myelitis following umbilical cord blood transplantation. 61
27459097 2016
19
Cord blood transplantation in Japan. 61
27263776 2016
20
[Cognitive Impairment in Patients with Bacterial Meningitis and Encephalitides]. 61
27056850 2016
21
[Human herpesvirus-6-associated diseases in hematopoietic stem cell transplantation: an update]. 61
27076241 2016
22
HHV-6 encephalitis may complicate the early phase after allogeneic hematopoietic stem cell transplantation: Detection by qualitative multiplex PCR and subsequent quantitative real-time PCR. 61
26241219 2016
23
[Human herpesvirus-6 associated with hematopoietic stem cell transplantation]. 61
26458456 2015
24
Diagnostic Clues to Human Herpesvirus 6 Encephalitis and Wernicke Encephalopathy After Pediatric Hematopoietic Cell Transplantation. 61
25564483 2015
25
Human herpesvirus-6 encephalitis after allogeneic hematopoietic cell transplantation: what we do and do not know. 61
25915811 2015
26
Ganciclovir-resistant HHV-6 encephalitis that progressed rapidly after bone marrow transplantation. 61
26209402 2015
27
[Human Herpesvirus-6 Encephalitis in Allogeneic Hematopoietic Stem Cell Transplantation]. 61
26160819 2015
28
Human Herpesvirus-6 Pneumonitis around the Engraftment of Cord Blood Transplantation following Foscarnet Prophylaxis in a Patient with Acute Leukemia. 61
25650037 2015
29
[Epileptic encephalopathy associated with human herpes virus 6 (HHV-6) encephalitis after the second cord blood transplantation in a patient with pediatric acute lymphoblastic leukemia]. 61
25744043 2014
30
Encephalitis caused by human herpesvirus-6B in pancreas-after-kidney transplantation. 61
25040797 2014
31
HHV-6 encephalitis presenting as status epilepticus in an immunocompetent patient. 61
25239996 2014
32
Human Herpesvirus-6 Encephalitis After Hematopoietic Stem Cell Transplantation. 61
26114018 2014
33
Anterior Commissure Involvement in Humanherpes Virus 6 Encephalitis. 61
28503579 2014
34
Frequent human herpesvirus-6 viremia but low incidence of encephalitis in double-unit cord blood recipients transplanted without antithymocyte globulin. 61
24548875 2014
35
Child and adult forms of human herpesvirus 6 encephalitis: looking back, looking forward. 61
24792343 2014
36
Status Epilepticus due to Severe HHV-6 Encephalitis in an Allogeneic Stem Cell Transplant Recipient. 61
24455117 2014
37
[Human herpesvirus 6 encephalitis in a patient with glucocorticoid therapy for inflammatory abdominal aortic aneurysm]. 61
24835137 2014
38
Human herpesvirus 6 (HHV-6) reactivation and HHV-6 encephalitis after allogeneic hematopoietic cell transplantation: a multicenter, prospective study. 61
23723198 2013
39
Human herpesvirus-6 encephalitis during hematopoietic stem cell transplantation leads to poor prognosis. 61
23331378 2013
40
HHV-6 encephalitis in umbilical cord blood transplantation: a systematic review and meta-analysis. 61
23000642 2013
41
Human herpes 6 virus encephalitis complicating allogeneic hematopoietic stem cell transplantation. 61
23516318 2013
42
Foscarnet against human herpesvirus (HHV)-6 reactivation after allo-SCT: breakthrough HHV-6 encephalitis following antiviral prophylaxis. 61
22750998 2013
43
Successful ganciclovir therapy in a patient with human herpesvirus-6 encephalitis after unrelated cord blood transplantation: usefulness of longitudinal measurements of viral load in cerebrospinal fluid. 61
22971937 2013
44
Human herpesvirus 6 encephalitis simulating brain metastases in a patient with advanced small-cell lung cancer. 61
24852190 2013
45
Multiple viral infections after haploidentical hematopoietic stem cell transplantation in a child with acute lymphoblastic leukemia. 61
22862952 2012
46
Safety of pre-engraftment prophylactic foscarnet administration after allogeneic stem cell transplantation. 61
21794043 2012
47
Lethal human herpesvirus-6 encephalitis after cord blood transplant. 61
21883755 2011
48
Long-term outcome of human herpesvirus-6 encephalitis after allogeneic stem cell transplantation. 61
21296175 2011
49
Subtype-specific, probe-based, real-time PCR for detection and typing of human herpesvirus-6 encephalitis from pediatric patients under the age of 2 years. 61
21429693 2011
50
Preemptive therapy of human herpesvirus-6 encephalitis with foscarnet sodium for high-risk patients after hematopoietic SCT. 61
20838386 2011

Variations for Hhv-6 Encephalitis

Expression for Hhv-6 Encephalitis

Search GEO for disease gene expression data for Hhv-6 Encephalitis.

Pathways for Hhv-6 Encephalitis

GO Terms for Hhv-6 Encephalitis

Sources for Hhv-6 Encephalitis

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
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30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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43 MeSH
44 MESH via Orphanet
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48 NCI
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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