Aliases & Classifications for Hidradenitis

MalaCards integrated aliases for Hidradenitis:

Name: Hidradenitis 12 44 15 73
Hydradenitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2282
ICD9CM 35 705.83
MeSH 44 D016575
NCIt 50 C112190
UMLS 73 C0085160

Summaries for Hidradenitis

MalaCards based summary : Hidradenitis, also known as hydradenitis, is related to pyoderma gangrenosum and pyoderma. An important gene associated with Hidradenitis is NCSTN (Nicastrin), and among its related pathways/superpathways are Developmental Biology and Keratinization. The drugs Adalimumab and Anti-Inflammatory Agents have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, skin and testes, and related phenotypes are craniofacial and hematopoietic system

Related Diseases for Hidradenitis

Diseases related to Hidradenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 pyoderma gangrenosum 30.9 NOD2 TNF
2 pyoderma 30.9 NOD2 TNF
3 spondyloarthropathy 1 29.6 IL17A NOD2 TNF
4 spondylitis 29.6 IL17A NOD2 TNF
5 colitis 29.5 IL17A NOD2 TNF
6 psoriasis 29.1 IL17A KRT10 KRT14 TNF
7 skin disease 28.7 IL17A KRT10 KRT14 TNF
8 hidradenitis suppurativa 27.3 DSC2 DSG2 IL12RB1 IL17A KRT10 KRT14
9 pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 12.0
10 perifolliculitis capitis abscedens et suffodiens, familial 11.3
11 acne inversa, familial, 1 11.2
12 papillon-lefevre syndrome 10.9
13 acne inversa, familial, 2, with or without dowling-degos disease 10.9
14 acne inversa, familial, 3 10.9
15 sebaceous gland disease 10.7 NCSTN PSENEN
16 granulomatous dermatitis 10.6 NOD2 TNF
17 ileocolitis 10.6 NOD2 TNF
18 crohn's colitis 10.6 NOD2 TNF
19 ocular toxoplasmosis 10.5 IL17A NOD2
20 inflammatory bowel disease 3 10.5 NOD2 TNF
21 rheumatoid lung disease 10.5 IL17A TNF
22 orofacial granulomatosis 10.5 NOD2 TNF
23 trichosporonosis 10.5 IL17A TNF
24 streptococcal meningitis 10.5 NOD2 TNF
25 blau syndrome 10.5 NOD2 TNF
26 central nervous system vasculitis 10.5 IL17A TNF
27 transverse myelitis 10.4 IL17A TNF
28 primary systemic mycosis 10.4 IL17A TNF
29 anal canal squamous cell carcinoma 10.4 NCSTN PSEN1 PSENEN
30 myelitis 10.4 IL17A TNF
31 stromal keratitis 10.4 IL17A TNF
32 panuveitis 10.4 IL17A TNF
33 q fever 10.3 NOD2 TNF
34 joint disorders 10.3 IL17A TNF
35 hypersensitivity reaction type iv disease 10.3 NOD2 TNF
36 basal cell carcinoma, infundibulocystic 10.3 KRT10 KRT14
37 filamentary keratitis 10.3 IL17A KRT10
38 large cell acanthoma 10.3 KRT10 KRT14
39 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT10 KRT14
40 striate palmoplantar keratoderma 10.3 KRT10 KRT14
41 breast squamous cell carcinoma 10.3 KRT10 KRT14
42 cutaneous candidiasis 10.2 IL12RB1 IL17A
43 epidermolysis bullosa simplex, dowling-meara type 10.2 KRT10 KRT14
44 squamous cell carcinoma 10.2
45 acute graft versus host disease 10.2 NOD2 TNF
46 crohn's disease 10.2
47 extrinsic cardiomyopathy 10.2 IL17A TNF
48 inflammatory bowel disease 6 10.2 IL12RB1 NOD2
49 ichthyosis vulgaris 10.2 KRT10 KRT14
50 ileitis 10.2 IL17A NOD2 TNF

Graphical network of the top 20 diseases related to Hidradenitis:



Diseases related to Hidradenitis

Symptoms & Phenotypes for Hidradenitis

MGI Mouse Phenotypes related to Hidradenitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.35 IL17A KRT14 NCSTN PSEN1 TNF
2 hematopoietic system MP:0005397 9.17 IL12RB1 IL17A KRT14 NCSTN NOD2 PSEN1

Drugs & Therapeutics for Hidradenitis

Drugs for Hidradenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 72)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Adalimumab Approved Phase 4,Phase 3,Phase 2 331731-18-1 16219006
2 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
3 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
4 Anesthetics Phase 4,Phase 1
5 Anti-Bacterial Agents Phase 3,Phase 2,Not Applicable
6 Antibiotics, Antitubercular Phase 3,Not Applicable
7
Apremilast Approved, Investigational Phase 2 608141-41-9 11561674
8
Infliximab Approved Phase 2 170277-31-3
9
Etanercept Approved, Investigational Phase 2 185243-69-0
10
Ustekinumab Approved, Investigational Phase 2 815610-63-0
11
Hydroxychloroquine Approved Phase 1, Phase 2 118-42-3 3652
12
Drospirenone Approved Phase 2 67392-87-4 68873
13
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
14 Estradiol valerate Approved, Investigational, Vet_approved Phase 2 979-32-8
15
Ethinyl Estradiol Approved Phase 2 57-63-6 5991
16
Polyestradiol phosphate Approved Phase 2 28014-46-2
17 Anti-Infective Agents Phase 2,Phase 1,Not Applicable
18 Immunosuppressive Agents Phase 2,Not Applicable
19 Dermatologic Agents Phase 2,Not Applicable
20 Hormone Antagonists Phase 2,Not Applicable
21 Hormones Phase 2,Not Applicable
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2,Not Applicable
23 Antibodies Phase 2,Phase 1,Early Phase 1
24 Antibodies, Monoclonal Phase 2,Phase 1,Early Phase 1
25 Immunoglobulins Phase 2,Phase 1,Early Phase 1
26 Analgesics Phase 2
27 Analgesics, Non-Narcotic Phase 2
28 Angiogenesis Inhibitors Phase 2
29 Angiogenesis Modulating Agents Phase 2
30 Anti-Inflammatory Agents, Non-Steroidal Phase 2
31 Peripheral Nervous System Agents Phase 2,Not Applicable
32 Interleukin 1 Receptor Antagonist Protein Phase 2
33 Gastrointestinal Agents Phase 2
34 Complement System Proteins Phase 2
35 Antimalarials Phase 1, Phase 2
36 Antiparasitic Agents Phase 1, Phase 2
37 Antiprotozoal Agents Phase 1, Phase 2
38 Contraceptive Agents Phase 2
39 Contraceptives, Oral Phase 2
40 diuretics Phase 2
41 Diuretics, Potassium Sparing Phase 2
42 Drospirenone and ethinyl estradiol combination Phase 2
43 Estradiol 17 beta-cypionate Phase 2
44 Estradiol 3-benzoate Phase 2
45 Estrogens Phase 2
46 Mineralocorticoid Receptor Antagonists Phase 2
47 Mineralocorticoids Phase 2
48 Natriuretic Agents Phase 2
49
Phenol Approved, Experimental Phase 1 108-95-2 996
50 Pharmaceutical Solutions Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 60)
# Name Status NCT ID Phase Drugs
1 Safety and Efficacy of Humira (Adalimumab) for Hidradenitis Suppurativa (HS) Peri-Surgically (SHARPS Study) Recruiting NCT02808975 Phase 4 Adalimumab;Placebo
2 Cost-effectiveness of Adalimumab and Surgery vs Adalimumab in HS Not yet recruiting NCT03221621 Phase 4 Adalimumab Injection
3 Efficacy and Safety Study of Adalimumab in Treatment of Hidradenitis Suppurativa Completed NCT01468207 Phase 3
4 Efficacy and Safety Study of Adalimumab in the Treatment of Hidradenitis Suppurativa Completed NCT01468233 Phase 3
5 Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa Completed NCT01635764 Phase 3
6 Effect of Sclerotherapy on Fistulas and Sinus Tracts in Hidradenitis Suppurativa Recruiting NCT02805595 Phase 3 23.4% Hypertonic saline;Saline
7 Open-label Study of Adalimumab in Japanese Subjects With Hidradenitis Suppurativa Active, not recruiting NCT02904902 Phase 3 Adalimumab
8 To Determine the Efficacy of a Laser Device for the Treatment of Hidradenitis Suppurativa Terminated NCT00367328 Phase 3
9 Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients Completed NCT02421172 Phase 2
10 Single Center Study of Apremilast for the Treatment of Hidradenitis Suppurativa Completed NCT02695212 Phase 2 Apremilast
11 To Assess the Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Hidradenitis Suppurativa Completed NCT00827996 Phase 2 adalimumab
12 Anakinra as a Treatment for Hydradenitis Suppurativa Completed NCT01516749 Phase 2 anakinra
13 Study to Assess the Safety and Efficacy of Infliximab to Treat Hidradenitis Suppurtativa Completed NCT00795574 Phase 2 infliximab;Placebo Comparator
14 Studying Complement Inhibition in Patients With Moderate to Severe Hidradenitis Suppurativa Completed NCT03001622 Phase 2
15 Etanercept in Hidradenitis Suppurativa Completed NCT00329823 Phase 2 Etanercept sc 50mg per week for 12 weeks
16 Anakinra in Hidradenitis Suppurativa Completed NCT01558375 Phase 2 Water for injection;Anakinra
17 Etanercept for Treatment of Hidradenitis Completed NCT00107991 Phase 2 etanercept
18 MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB Completed NCT02643654 Phase 2 MABp1;Placebo
19 A Proof of Concept Study to Evaluate the Effectiveness of Ustekinumab in Hidradenitis Suppurativa Completed NCT01704534 Phase 2 Ustekinumab
20 Short-term Safety, Efficacy and Mode of Action of Apremilast in Moderate Suppurative Hidradenitis Completed NCT03049267 Phase 2 Apremilast;Placebo Oral Tablet
21 Study of Adalimumab in Subjects With Moderate to Severe Chronic Hidradenitis Suppurativa Completed NCT00918255 Phase 2 Placebo
22 A Study of MABp1 in Patients With Hidradenitis Suppurativa Recruiting NCT03512275 Phase 2 MABp1 Monoclonal Antibody 200 mg;MABp1 Monoclonal Antibody 400 mg
23 Efficacy and Safety Study of IFX-1 in Patients With Moderate to Severe Hidradenitis Suppurativa (HS) Recruiting NCT03487276 Phase 2 IFX-1;Placebo
24 Hydroxychloroquine for the Treatment of Hidradenitis Suppurativa Recruiting NCT03275870 Phase 1, Phase 2 Hydroxychloroquine
25 A Study to Test the Efficacy, Safety and Pharmacokinetics of Bimekizumab in Subjects With Moderate to Severe Hidradenitis Suppurativa. Active, not recruiting NCT03248531 Phase 2 Bimekizumab;Adalimumab
26 A Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa Not yet recruiting NCT03569371 Phase 2 INCB054707
27 Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa Terminated NCT01838499 Phase 2
28 A Study to Examine the Safety and Efficacy of Drospirenone and Ethinyl Estradiol (YAZ) Versus Placebo In HS Terminated NCT00722800 Phase 2 drospirenone and ethinyl estradiol (YAZ);Placebo
29 Efficacy and Safety of Efalizumab in the Treatment of Moderate-Severe Hydradenitis Suppurativa Completed NCT00134134 Phase 1 efalizumab
30 Endoscopic Pilonidal Sinus Treatment With Additional Crystalized Phenol Completed NCT02277340 Phase 1
31 An Investigation Into the Efficacy of Provodine Topical Cream as Compared to 10% Benzoyl Peroxide Wash for the Treatment of Hidradenitis Suppurativa. Unknown status NCT01818167 Not Applicable 10% Benzoyl Peroxide Topical Body Wash;Provodine Topical Cream
32 Study to Compare Two Treatments for Axillary Hidradenitis Suppurativa: Carbon Dioxide Laser Versus Surgical Deroofing Unknown status NCT02163746 Not Applicable
33 Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa Unknown status NCT01063270 Not Applicable Clindamycin & Rifampin
34 Efficacy of Percutaneous Injection of Triamcinolone in the Treatment of Mammillary Fistula Unknown status NCT01315080
35 A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa. Completed NCT02781818 Not Applicable Triamcinolone Acetonide 10mg/mL;Triamcinolone Acetonide 40mg/mL;Normal Saline
36 Study on the Effect of NdYag Laser for the Treatment of Hidradenitis Suppurativa Completed NCT00494351 Not Applicable
37 Post Marketing Observational Study (PMOS) to Assess Quality of Life in Swedish Hidradenitis Suppurativa (HS) Patients Completed NCT02739828
38 Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients Completed NCT02833909 Not Applicable
39 Quality of Life After Wide Surgical Excision in Patients With Hidradenitis Suppurativa Completed NCT02593604
40 A Small Clinical Study: Photodynamic Therapy to Treat Hidradenitis Suppurativa Completed NCT00395187 Not Applicable
41 Treatment of Hidradenitis Suppurativa Using Etanercept Completed NCT00949546 etanercept
42 Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser Recruiting NCT03054155 Not Applicable
43 Post-Marketing Surveillance of Adalimumab in Korean Hidradenitis Suppurativa Subjects Recruiting NCT03001115
44 A National Registry For Patients With Hidradenitis Suppurativa Recruiting NCT03289585
45 Group Psychotherapy for Patients With Hidradenitis Suppurativa: Effects in Quality of Life Recruiting NCT02904408 Not Applicable
46 Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa Recruiting NCT03040804 Not Applicable
47 Exploratory Trial Evaluating Cosentyx (Secukinumab) for Patients With Moderate-to-Severe Hidradenitis Suppurativa Recruiting NCT03099980 Early Phase 1
48 Hidradenitis Suppurativa and Periodontal Diseases Recruiting NCT03553888
49 Impact of Hidradenitis Suppurativa on Quality of Life Functions Recruiting NCT03288337
50 The Ohio State University Dermatology Biorepository, Molecular Biology and Genetics of Hidradenitis Suppurativa Recruiting NCT03146676

Search NIH Clinical Center for Hidradenitis

Cochrane evidence based reviews: hidradenitis

Genetic Tests for Hidradenitis

Anatomical Context for Hidradenitis

MalaCards organs/tissues related to Hidradenitis:

41
Neutrophil, Skin, Testes, Thyroid, Myeloid, Pituitary, Monocytes

Publications for Hidradenitis

Articles related to Hidradenitis:

(show top 50) (show all 794)
# Title Authors Year
1
The in-hospital burden of hidradenitis suppurativa in patients with inflammatory bowel disease: a decade nationwide analysis from 2004 to 2014. ( 29431201 )
2018
2
Distinguishing Mild, Moderate, and Severe Hidradenitis Suppurativa. ( 29926079 )
2018
3
Incidence of Obstructive Sleep Apnea among Patients with Hidradenitis Suppurativa: a retrospective population-based cohort analysis. ( 29957857 )
2018
4
Safety of Adalimumab Dosed Every Week and Every Other Week: Focus on Patients with Hidradenitis Suppurativa or Psoriasis. ( 29380251 )
2018
5
The immunological disease continuum of inflammation against self as an explanation for the lack of association between hidradenitis suppurativa and autoimmune thyroid disease. ( 29327479 )
2018
6
Acne and hidradenitis suppurativa. ( 29380349 )
2018
7
Combined fractional carbon dioxide laser and long-pulsed neodymium : yttrium-aluminium-garnet (1064 nm) laser in treatment of hidradenitis suppurativa; a prospective randomized intra-individual controlled study. ( 29907956 )
2018
8
Hidradenitis suppurativa, a review of pathogenesis, associations and management. Part 2. ( 29363099 )
2018
9
Current and future treatment of hidradenitis suppurativa. ( 29981245 )
2018
10
Laser hair removal alters the disease course in mild hidradenitis suppurativa. ( 29933519 )
2018
11
Concurrent hidradenitis suppurativa and Dowling-Degos disease taken down a 'Notch'. ( 29441533 )
2018
12
Hidradenitis suppurativa is associated with polycystic ovary syndrome: a population-based analysis in the United States. ( 29378201 )
2018
13
Anti-TNFI+ therapy modulates mTORC1signalling in hidradenitis suppurativa. ( 29956847 )
2018
14
Acquired lymphangioma circumscriptum of the genitals in an individual with chronic hidradenitis suppurativa. ( 29387752 )
2018
15
Women with Hidradenitis Suppurativa Have an Elevated Risk of Suicide. ( 29959906 )
2018
16
Longitudinal observational study of hidradenitis suppurativa: impact of surgical intervention with adjunctive biologic therapy. ( 29130482 )
2018
17
Hidradenitis suppurativa, a review of pathogenesis, associations and management. Part 1. ( 29355905 )
2018
18
Surgical management of hidradenitis suppurativa: procedural trends and risk factors. ( 29936991 )
2018
19
Secondary gastrointestinal amyloid A amyloidosis possibly caused by hidradenitis suppurativa. ( 29933503 )
2018
20
Distinguishing Mild, Moderate, and Severe Hidradenitis Suppurativa. ( 29926084 )
2018
21
Radical resection and local coverage of hidradenitis suppurativa - acne inversa: analysis of results. ( 29924129 )
2018
22
Risk Factors for Hidradenitis Suppurativa in Patients with Inflammatory Bowel Disease. ( 29357084 )
2018
23
Blood parameters in a population of blood donors are not affected by hidradenitis suppurativa. ( 29952294 )
2018
24
Comment on "Hidradenitis suppurativa in children treated with finasteride-A case series". ( 29356110 )
2018
25
A case of pyoderma gangrenosum, acne, hidradenitis suppurativa (PASH) syndrome associated with diabetes mellitus type 1 treated with adalimumab. ( 29368847 )
2018
26
Patients affected by Dent disease 2 could be predisposed to hidradenitis suppurativa. ( 29430722 )
2018
27
A Novel Severity Assessment Scoring System for Hidradenitis Suppurativa. ( 29417136 )
2018
28
Squamous cell carcinoma of the perineum masquerading as necrotizing hidradenitis suppurativa. ( 29906008 )
2018
29
A case of Axillary Hidradenitis suppurativa treated with topical tacrolimus. ( 29368858 )
2018
30
Growing evidence for coronary artery disease risk factors in patients with severe hidradenitis suppurativa. ( 29357611 )
2018
31
Congenital nevus comedonicus complicated by a hidradenitis suppurativa-like lesion: Report of a childhood case. ( 29952017 )
2018
32
Reliability of the hidradenitis suppurativa clinical response (HiSCR) in the assessment of patients with hidradenitis suppurativa. ( 29959796 )
2018
33
The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore. ( 29403298 )
2018
34
Hidradenitis Suppurativa in Kuala Lumpur, Malaysia: A 7-Year Retrospective Review. ( 29951091 )
2018
35
Prevalence of Type II Diabetes Mellitus Among Patients with Hidradenitis Suppurativa in the United States. ( 29339240 )
2018
36
Aggravation of mild axillary hidradenitis suppurativa by microwave ablation: results of a randomized intra-patient controlled trial. ( 29940205 )
2018
37
HIDRAdisk: an innovative visual tool to assess the burden of hidradenitis suppurativa. ( 29894009 )
2018
38
Drug-induced sarcoidosis in a patient treated with an interleukin-1 receptor antagonist for hidradenitis suppurativa. ( 29892670 )
2018
39
Hidradenitis suppurativa with SAPHO syndrome maintained effectively with adalimumab, methotrexate, and intralesional corticosteroid injections. ( 29922466 )
2018
40
Complement activation in hidradenitis suppurativa: a new pathway of pathogenesis? ( 29405257 )
2018
41
Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa. ( 28052274 )
2017
42
Weekly adalimumab significantly reduces the number of abscesses and inflammatory nodules in patients with moderate to severe hidradenitis suppurativa. ( 28053204 )
2017
43
Interferon-gamma (IFN-I^) is Elevated in Wound Exudate from Hidradenitis Suppurativa. ( 27819528 )
2017
44
Glucagon-like peptide-1 agonists for treatment of hidradenitis suppurativa. ( 28940285 )
2017
45
Increased Suicide Risk in Patients with Hidradenitis Suppurativa. ( 28942360 )
2017
46
Disseminate recurrent folliculitis as the presenting picture of hidradenitis suppurativa. ( 28838562 )
2017
47
Novel POFUT1 mutation associated with hidradenitis suppurativa-Dowling-Degos disease firm up a role for Notch signalling in the pathogenesis of this disorder. ( 29274243 )
2017
48
Body fat composition in hidradenitis suppurativa: a hospital-based cross-sectional study. ( 28084004 )
2017
49
Hidradenitis Suppurativa in Down Syndrome: A Case Series. ( 28636122 )
2017
50
Prevalence and risk of inflammatory bowel disease in patients with hidradenitis suppurativa. ( 28089682 )
2017

Variations for Hidradenitis

Expression for Hidradenitis

Search GEO for disease gene expression data for Hidradenitis.

Pathways for Hidradenitis

Pathways related to Hidradenitis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.01 DSC2 DSG2 KRT10 KRT14 NCSTN PSENEN
2
Show member pathways
12.21 DSC2 DSG2 KRT10 KRT14
3
Show member pathways
12.16 IL12RB1 IL17A NOD2 TNF
4
Show member pathways
12 IL12RB1 IL17A TNF
5 11.97 NCSTN PSEN1 PSENEN
6
Show member pathways
11.93 NCSTN PSEN1 PSENEN
7 11.82 NCSTN PSEN1 PSENEN
8 11.56 IL12RB1 IL17A TNF
9
Show member pathways
11.4 NCSTN PSEN1 PSENEN
10 11.24 NCSTN PSEN1 PSENEN
11 11.06 IL17A TNF
12 10.99 NCSTN PSEN1 PSENEN
13 10.87 NOD2 TNF
14 10.49 NCSTN PSEN1 PSENEN
15 10.07 PSEN1 PSENEN
16 10.03 NCSTN PSEN1 PSENEN

GO Terms for Hidradenitis

Cellular components related to Hidradenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.56 DSG2 NOD2 PSEN1 TNF
2 desmosome GO:0030057 9.16 DSC2 DSG2
3 cornified envelope GO:0001533 9.13 DSC2 DSG2 KRT10
4 gamma-secretase complex GO:0070765 8.8 NCSTN PSEN1 PSENEN

Biological processes related to Hidradenitis according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.86 NCSTN PSEN1 PSENEN TNF
2 keratinization GO:0031424 9.76 DSC2 DSG2 KRT10 KRT14
3 Notch signaling pathway GO:0007219 9.75 NCSTN PSEN1 PSENEN
4 cornification GO:0070268 9.73 DSC2 DSG2 KRT10 KRT14
5 positive regulation of catalytic activity GO:0043085 9.71 NCSTN PSEN1 PSENEN
6 ephrin receptor signaling pathway GO:0048013 9.7 NCSTN PSEN1 PSENEN
7 protein processing GO:0016485 9.69 NCSTN PSEN1 PSENEN
8 positive regulation of MAP kinase activity GO:0043406 9.65 NOD2 PSEN1 TNF
9 regulation of heart rate by cardiac conduction GO:0086091 9.62 DSC2 DSG2
10 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 NOD2 TNF
11 positive regulation of interleukin-8 production GO:0032757 9.61 NOD2 TNF
12 positive regulation of osteoclast differentiation GO:0045672 9.6 IL17A TNF
13 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.59 IL17A NOD2
14 amyloid-beta metabolic process GO:0050435 9.58 NCSTN PSEN1
15 membrane protein ectodomain proteolysis GO:0006509 9.58 NCSTN PSEN1 PSENEN
16 epithelial cell proliferation GO:0050673 9.57 NCSTN PSEN1
17 regulation of ventricular cardiac muscle cell action potential GO:0098911 9.55 DSC2 DSG2
18 membrane protein intracellular domain proteolysis GO:0031293 9.54 NCSTN PSEN1 PSENEN
19 Notch receptor processing GO:0007220 9.5 NCSTN PSEN1 PSENEN
20 bundle of His cell-Purkinje myocyte adhesion involved in cell communication GO:0086073 9.49 DSC2 DSG2
21 Notch receptor processing, ligand-dependent GO:0035333 9.43 NCSTN PSEN1 PSENEN
22 amyloid precursor protein metabolic process GO:0042982 9.33 NCSTN PSEN1 PSENEN
23 amyloid precursor protein catabolic process GO:0042987 9.13 NCSTN PSEN1 PSENEN
24 amyloid-beta formation GO:0034205 8.8 NCSTN PSEN1 PSENEN

Molecular functions related to Hidradenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication GO:0086083 8.62 DSC2 DSG2

Sources for Hidradenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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