MCID: HST009
MIFTS: 50

Histiocytoma

Categories: Cancer diseases

Aliases & Classifications for Histiocytoma

MalaCards integrated aliases for Histiocytoma:

Name: Histiocytoma 12 29 44 15 73
Cutaneous Fibrous Histiocytoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4231
MeSH 44 D051642
NCIt 50 C35765
SNOMED-CT 68 72079004

Summaries for Histiocytoma

MalaCards based summary : Histiocytoma, also known as cutaneous fibrous histiocytoma, is related to malignant fibrous histiocytoma of bone and fibrous histiocytoma. An important gene associated with Histiocytoma is MFHAS1 (Malignant Fibrous Histiocytoma Amplified Sequence 1), and among its related pathways/superpathways are Pathways in cancer and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Mechlorethamine and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and breast, and related phenotypes are muscle and neoplasm

Wikipedia : 76 A histiocytoma is a tumour consisting of histiocytes. Histiocytes are cells that are a part of the... more...

Related Diseases for Histiocytoma

Diseases related to Histiocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 284)
# Related Disease Score Top Affiliating Genes
1 malignant fibrous histiocytoma of bone 33.3 MDM2 MYOD1
2 fibrous histiocytoma 33.2 ATF1 CD163 CREB1 EWSR1 FUS MFHAS1
3 malignant fibroxanthoma 33.0 MDM2 MYOD1 PTPRC SERPINA3
4 reticulohistiocytic granuloma 31.8 CD163 MITF PTPRC SERPINA3
5 histiocytosis 30.3 CD163 PTPRC SERPINA3
6 sarcoma 30.2 ATF1 EWSR1 FUS KIT MDM2 MTAP
7 dermatofibrosarcoma protuberans 30.2 KIT SERPINA3 TP53
8 leiomyosarcoma 30.1 KIT MB MDM2 TP53
9 dedifferentiated liposarcoma 30.1 MB MDM2 TP53
10 soft tissue sarcoma 30.0 EWSR1 MDM2 TP53
11 inflammatory mfh 29.8 MDM2 SERPINA3
12 fibrosarcoma of bone 29.8 KIT MDM2 SERPINA3
13 liposarcoma 29.8 EWSR1 FUS MB MDM2 TP53 TSPAN31
14 lymphoma, non-hodgkin, familial 29.5 ALK MDM2 PTPRC TP53
15 mixed cell type cancer 29.5 KIT MB TP53
16 rhabdoid cancer 29.4 EWSR1 MB MYOD1 TP53
17 undifferentiated embryonal sarcoma of the liver 29.4 MDM2 MYOD1 SERPINA3
18 pleomorphic rhabdomyosarcoma 29.4 MB MYOD1
19 myxoid liposarcoma 29.4 ATF1 EWSR1 FUS MDM2 TP53
20 inflammatory myofibroblastic tumor 29.3 ALK KIT MDM2 TP53
21 embryonal sarcoma 29.3 KIT MDM2 MYOD1 SERPINA3 TP53
22 rhabdomyosarcoma 28.6 ALK EWSR1 MB MDM2 MYOD1 PTPRC
23 diaphyseal medullary stenosis with malignant fibrous histiocytoma 12.6
24 histiocytoma, angiomatoid fibrous 12.5
25 cutaneous fibrous histiocytoma 12.5
26 malignant skin fibrous histiocytoma 12.1
27 undifferentiated pleomorphic sarcoma 12.1
28 benign deep fibrous histiocytoma 12.0
29 generalized eruptive histiocytosis 12.0
30 sclerosing hemangioma 11.9
31 myxofibrosarcoma 11.8
32 tenosynovial giant cell tumor 11.4
33 urachal cancer 11.0
34 pigmented villonodular synovitis 11.0
35 sarcomatosis 10.3 ATF1 EWSR1
36 proliferative fasciitis 10.2 MB SERPINA3
37 conventional central osteosarcoma 10.2 EWSR1 MDM2
38 melanoma of soft tissue 10.2 ATF1 CREB1 EWSR1
39 ring chromosome 7 10.2 MDM2 TP53
40 zika virus infection 10.2 MDM2 TP53
41 extraosseous chondrosarcoma 10.2 EWSR1 FUS
42 nodular tenosynovitis 10.2 PTPRC SERPINA3
43 actinic cheilitis 10.2 MDM2 TP53
44 cellular myxoid liposarcoma 10.2 EWSR1 FUS MDM2
45 parameningeal embryonal rhabdomyosarcoma 10.2 ALK TP53
46 dermis tumor 10.2 CD163 SERPINA3
47 meninges sarcoma 10.2 MB TP53
48 juxtacortical chondroma 10.2 EWSR1 FUS
49 fibrosarcoma 10.2
50 vulvar sarcoma 10.2 EWSR1 PTPRC

Graphical network of the top 20 diseases related to Histiocytoma:



Diseases related to Histiocytoma

Symptoms & Phenotypes for Histiocytoma

MGI Mouse Phenotypes related to Histiocytoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.87 CD163 CREB1 KIT MB MDM2 MYOD1
2 neoplasm MP:0002006 9.73 ALK KIT MDM2 MYOD1 PTPRC TP53
3 respiratory system MP:0005388 9.61 ALK CD163 CREB1 KIT MB MTAP
4 pigmentation MP:0001186 9.55 ALK KIT MDM2 MITF TP53
5 skeleton MP:0005390 9.23 ALK CREB1 KIT MDM2 MITF MYOD1

Drugs & Therapeutics for Histiocytoma

Drugs for Histiocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 110)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 51-75-2 4033
2
Ifosfamide Approved Phase 3,Phase 2,Phase 1,Not Applicable 3778-73-2 3690
3
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 23214-92-8 31703
4
Carboplatin Approved Phase 3 41575-94-4 10339178 38904 498142
5
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
6
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
7
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 6055-19-2, 50-18-0 2907
8
Vincristine Approved, Investigational Phase 3 57-22-7, 2068-78-2 5978
9
Epirubicin Approved Phase 3 56420-45-2 41867
10
Lenograstim Approved, Investigational Phase 3,Phase 2 135968-09-1
11
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
12
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1,Not Applicable 31703
13
Isophosphamide mustard Phase 3,Phase 2,Phase 1,Not Applicable 0
14 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1,Not Applicable
15 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1,Not Applicable
16 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1,Not Applicable
17 Alkylating Agents Phase 3,Phase 2,Phase 1,Not Applicable
18 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1,Not Applicable
19 Anti-Infective Agents Phase 3,Phase 2,Phase 1
20 Antineoplastic Agents, Phytogenic Phase 3,Phase 1,Phase 2
21 Immunologic Factors Phase 3,Phase 2,Phase 1
22 Etoposide phosphate Phase 3,Phase 2
23 Antimitotic Agents Phase 3,Phase 2,Phase 1
24 Antirheumatic Agents Phase 3,Phase 2,Phase 1
25 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
26 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
27
Ritonavir Approved, Investigational Phase 2 155213-67-5 392622
28
Indinavir Approved Phase 2 150378-17-9 5362440
29
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
30
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
31
Sunitinib Approved, Investigational Phase 2 557795-19-4, 341031-54-7 5329102
32
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
33
Bevacizumab Approved, Investigational Phase 2 216974-75-3
34
Docetaxel Approved, Investigational Phase 2,Phase 1 114977-28-5 148124
35
Nicotinamide Approved, Investigational Phase 2 98-92-0 936
36
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
37
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
38
Paclitaxel Approved, Vet_approved Phase 1, Phase 2,Phase 2 33069-62-4 36314
39
Sirolimus Approved, Investigational Phase 1, Phase 2,Phase 2 53123-88-9 46835353 6436030 5284616
40
Everolimus Approved Phase 1, Phase 2,Phase 2 159351-69-6 6442177
41
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2,Phase 2 22916-47-8 4189
42
Dasatinib Approved, Investigational Phase 2 302962-49-8 3062316
43
Pembrolizumab Approved Phase 1, Phase 2 1374853-91-4
44
Nivolumab Approved Phase 2,Phase 1 946414-94-4
45
Mesna Approved, Investigational Phase 2,Not Applicable 3375-50-6 598
46 Olaratumab Approved, Investigational Phase 2 1024603-93-7
47
Cisplatin Approved Phase 2 15663-27-1 2767 441203 84093
48
leucovorin Approved Phase 2 58-05-9 6006 143
49
Methotrexate Approved Phase 2 59-05-2, 1959-05-2 126941
50
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938

Interventional clinical trials:

(show top 50) (show all 72)
# Name Status NCT ID Phase Drugs
1 Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma Unknown status NCT00334854 Phase 3 doxorubicin hydrochloride;ifosfamide
2 Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma Unknown status NCT01344018 Phase 3
3 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
4 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
5 Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis Completed NCT00091351 Phase 3
6 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
7 Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00003212 Phase 3 doxorubicin hydrochloride;ifosfamide
8 Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00061984 Phase 3 doxorubicin hydrochloride;ifosfamide
9 Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00003052 Phase 3 doxorubicin hydrochloride;etoposide;ifosfamide
10 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
11 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
12 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Suspended NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
13 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3 doxorubicin hydrochloride;trabectedin
14 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
15 Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma Unknown status NCT00410462 Phase 2 brostallicin;doxorubicin hydrochloride
16 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2 temozolomide
17 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma Completed NCT00031915 Phase 2 imatinib mesylate
18 Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma Completed NCT00400569 Phase 2 Sunitinib Malate (SU011248)
19 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
20 Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes Completed NCT00887809 Phase 2 gemcitabine;docetaxel;bevacizumab
21 Bevacizumab and Radiation Therapy for Sarcomas Completed NCT00356031 Phase 2 Bevacizumab
22 Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung Completed NCT00503295 Phase 2
23 AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00659360 Phase 2 saracatinib
24 Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma Completed NCT00245102 Phase 2 sorafenib tosylate
25 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2 romidepsin
26 Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors Completed NCT01962103 Phase 1, Phase 2 nab-paclitaxel;nab-paclitaxel
27 Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma Completed NCT00085475 Phase 2 imatinib mesylate
28 Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma Completed NCT00949325 Phase 1, Phase 2 temsirolimus (Torisel) plus liposomal doxorubicin (Doxil)
29 Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00064220 Phase 2 soblidotin
30 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2 BI 2536
31 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2 trabectedin
32 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2 imatinib mesylate
33 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2 perifosine
34 Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00041249 Phase 2 brostallicin
35 Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00041236 Phase 2 exatecan mesylate
36 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01653028 Phase 2 Alisertib
37 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
38 Trial of Dasatinib in Advanced Sarcomas Completed NCT00464620 Phase 2 Dasatinib
39 Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma Recruiting NCT03123276 Phase 1, Phase 2 Pembrolizumab;Gemcitabine
40 Study of Neoadjuvant Checkpoint Blockade in Patients With Surgically Resectable Undifferentiated Pleomorphic Sarcoma and Dedifferentiated Liposarcoma Recruiting NCT03307616 Phase 2 Nivolumab;Ipilimumab
41 Autologous Dendritic Cell Vaccine Loaded With Allogeneic Tumor Lysate Expression of Cancer Testis Antigens in Patients With Soft Tissue Sarcoma Recruiting NCT01883518 Phase 1, Phase 2
42 Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma Recruiting NCT03190174 Phase 1, Phase 2 Nab-Rapamycin
43 Hypofractionated Radiotherapy With Sequential Chemotherapy in Primary Unresectable or Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall Recruiting NCT03651375 Phase 2 Sequential chemotherapy - 3 courses of AI
44 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2 Dexrazoxane;Doxorubicin;Olaratumab
45 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
46 A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma Active, not recruiting NCT00667342 Phase 2 Cisplatin;Doxorubicin;Methotrexate;Ifosfamide;etoposide
47 Gemcitabine, Cisplatin, and Abraxane in Advanced Biliary Cancers Active, not recruiting NCT02392637 Phase 2 Abraxane (Nab-Paclitaxel);Cisplatin;Gemcitabine
48 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Active, not recruiting NCT02601209 Phase 1, Phase 2 Pazopanib Hydrochloride;Sapanisertib
49 Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery Suspended NCT02923778 Phase 2
50 Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery Suspended NCT02500797 Phase 2

Search NIH Clinical Center for Histiocytoma

Cochrane evidence based reviews: histiocytoma

Genetic Tests for Histiocytoma

Genetic tests related to Histiocytoma:

# Genetic test Affiliating Genes
1 Histiocytoma 29

Anatomical Context for Histiocytoma

MalaCards organs/tissues related to Histiocytoma:

41
Bone, Lung, Breast, Liver, Skin, Heart, Colon

Publications for Histiocytoma

Articles related to Histiocytoma:

(show top 50) (show all 1526)
# Title Authors Year
1
Giant malignant fibrous histiocytoma of the testis. ( 29484233 )
2018
2
Retroperitoneal Angiomatoid Fibrous Histiocytoma Presenting as a Recurrent Spontaneous Retroperitoneal Hemorrhage in a 9-Year-Old Boy. ( 29432314 )
2018
3
Primary intracranial angiomatoid fibrous histiocytoma: a case report and literature review. ( 29540076 )
2018
4
Epithelioid cell histiocytoma with SQSTM1-ALK fusion: a case report. ( 29747676 )
2018
5
ALK Expression in Angiomatoid Fibrous Histiocytoma: A Potential Diagnostic Pitfall. ( 29877921 )
2018
6
Therapeutic response of metastatic angiomatoid fibrous histiocytoma carrying EWSR1-CREB1 fusion to the interleukin-6 receptor antibody tocilizumab. ( 29932283 )
2018
7
Giant Aneurysmal Benign Fibrous Histiocytoma (Dermatofibroma). ( 29956351 )
2018
8
Low-Grade Malignant Fibrous Histiocytoma Originating From the Medial Rectus Muscle. ( 29538190 )
2018
9
Immunohistochemical Labeling of Multiple Myeloma Oncogene 1/Interferon Regulatory Factor 4 (MUM1/IRF-4) in Canine Cutaneous Histiocytoma. ( 29444632 )
2018
10
Angiomatoid Fibrous Histiocytoma With Paraneoplastic Platelet Storage Pool Deficiency. ( 29472492 )
2018
11
A subset of so-called dermal non-neural granular cell tumours are underlined by ALK fusions, further supporting the idea that they represent a variant of epithelioid fibrous histiocytoma. ( 29742298 )
2018
12
Epithelioid fibrous histiocytoma: molecular characterization of ALK fusion partners in 23 cases. ( 29327718 )
2018
13
ALK Gene Fusions in Epithelioid Fibrous Histiocytoma: A Study of 14 Cases, With New Histopathological Findings. ( 29329131 )
2018
14
"Chondroblastoma-like" epithelioid fibrous histiocytoma: A previously undescribed and potentially confusing variant. ( 29068085 )
2018
15
Fibrous Histiocytoma of the Lacrimal Sac in an 11-Year-Old Male. ( 29494378 )
2018
16
Unusual Uptake of 131I in a Cutaneous Benign Fibrous Histiocytoma in a Patient With Thyroid Cancer. ( 29076899 )
2018
17
ESWR1-CREM Fusion in an Intracranial Myxoid Angiomatoid Fibrous Histiocytoma-Like Tumor: A Case Report and Literature Review. ( 29788195 )
2018
18
Primary Hepatic Malignant Fibrous Histiocytoma on PET/CT. ( 29485437 )
2018
19
Spindle cell predominant epithelioid fibrous histiocytoma. ( 29430713 )
2018
20
A Case of Angiomatoid Fibrous Histiocytoma Presenting as Subcutaneous Nodule in a 4-Year-Old Girl. ( 29606824 )
2018
21
Lipidized and aneurysmal fibrous histiocytoma with epithelial cysts on the left calf. ( 28225157 )
2018
22
Intracranial malignant fibrous histiocytoma. ( 29685317 )
2018
23
Fibrous histiocytoma as first presentation in systemic lupus erythematosus and sero-positive Sjögren's syndrome. ( 30094396 )
2018
24
Splenic malignant fibrous histiocytoma with concurrent hypertension and epistaxis in an Alaskan malamute dog. ( 30103739 )
2018
25
Aneurysmal fibrous histiocytoma. ( 30108116 )
2018
26
Application of 3D-printed PEEK scapula prosthesis in the treatment of scapular benign fibrous histiocytoma: A case report. ( 30123734 )
2018
27
The first ever reported case of malignant fibrous histiocytoma of the scalp. ( 30168269 )
2018
28
Treatment of angiomatoid fibrous histiocytoma after unplanned excision: a case report. ( 30170609 )
2018
29
Epithelioid Fibrous Histiocytoma: A Concise Review. ( 30289773 )
2018
30
Treatment of spinal malignant fibrous histiocytoma, a case report and literature review. ( 30527900 )
2018
31
Langerhans Cell Histiocytoma: A Benign Histiocytic Neoplasm of Diverse Lines of Terminal Differentiation. ( 30252693 )
2018
32
Treatment outcomes of malignant fibrous histiocytoma of the maxillary sinus. ( 28901310 )
2017
33
Malignant fibrous histiocytoma masquerading as pyogenic granuloma. ( 28388346 )
2017
34
Primary Pulmonary Malignant Fibrous Histiocytoma. ( 29404161 )
2017
35
Primary pulmonary malignant fibrous histiocytoma: case report and literature review. ( 28932590 )
2017
36
Benign Fibrous Histiocytoma: An Uncommon Presentation. ( 28892910 )
2017
37
18F-FDG Uptake in Benign Fibrous Histiocytoma of Adrenal Gland: A Potential Pitfall. ( 28632691 )
2017
38
Deep Benign Fibrous Histiocytoma of the Anterior Mediastinum Mimicking Malignancy. ( 28497381 )
2017
39
TLE-1-Positive Angiomatoid Fibrous Histiocytoma Mimicking Synovial Sarcoma. ( 28248724 )
2017
40
Malignant fibrous histiocytoma: Database review suggests a favorable prognosis in the head and neck. ( 28988458 )
2017
41
Malignant fibrous histiocytoma in the right portion of the mandible with metastasis in pancreas. ( 29040904 )
2017
42
Angiomatoid fibrous histiocytoma of the scalp mimicking cutaneous angiosarcoma in incisional biopsy containing CD31-positive histiocytes: A potential histopathological pitfall. ( 28370384 )
2017
43
Aneurysmal Variant of Fibrous Histiocytoma- A Rare Entity Known for Recurrence. ( 28764178 )
2017
44
Malignant fibrous histiocytoma arising from renal capsule: An extremely rare entity. ( 28937382 )
2017
45
En bloc resection and prosthesis implantation to treat malignant fibrous histiocytoma of the humerus. ( 29068573 )
2017
46
Cholesterotic Fibrous Histiocytoma in a Patient with Metabolic Syndrome. ( 29033817 )
2017
47
Primary hepatic malignant fibrous histiocytoma combined with invasion of inferior vena cava: A case report and literature review. ( 28591058 )
2017
48
Retrovesical malignant fibrous histiocytoma: a rare tumor. ( 29197849 )
2017
49
CORR Insights(Ar): Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28656494 )
2017
50
Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28536856 )
2017

Variations for Histiocytoma

Expression for Histiocytoma

Search GEO for disease gene expression data for Histiocytoma.

Pathways for Histiocytoma

GO Terms for Histiocytoma

Biological processes related to Histiocytoma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.95 ATF1 CREB1 EWSR1 FUS MITF MYOD1
2 transcription by RNA polymerase II GO:0006366 9.83 ATF1 CREB1 MITF MYOD1 TP53
3 negative regulation of apoptotic process GO:0043066 9.77 ALK KIT MDM2 MITF TP53
4 cell differentiation GO:0030154 9.73 ALK CREB1 KIT MITF MYOD1 TP53
5 protein-containing complex assembly GO:0065003 9.67 MDM2 MITF TP53
6 activation of MAPK activity GO:0000187 9.65 ALK KIT PTPRC
7 negative regulation of signal transduction GO:0009968 9.63 ALK KIT MFHAS1
8 positive regulation of protein export from nucleus GO:0046827 9.52 MDM2 TP53
9 melanocyte differentiation GO:0030318 9.51 KIT MITF
10 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.46 ALK KIT MFHAS1 PTPRC
11 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899 9.32 CREB1 TP53
12 regulation of gene expression GO:0010468 9.26 MDM2 MITF MYOD1 PTPRC
13 cellular response to actinomycin D GO:0072717 8.62 MDM2 TP53

Molecular functions related to Histiocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ubiquitin protein ligase binding GO:0031625 9.62 MDM2 MFHAS1 MYOD1 TP53
2 identical protein binding GO:0042802 9.5 ALK ATF1 CREB1 EWSR1 FUS MDM2
3 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.46 ATF1 CREB1 MYOD1 TP53
4 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 8.92 ATF1 CREB1 MITF MYOD1
5 protein binding GO:0005515 10.13 ALK ATF1 CD163 CREB1 EWSR1 FUS

Sources for Histiocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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