Histiocytoma, Angiomatoid Fibrous disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

AFH MCID: HST022 MIFTS: 29	Histiocytoma, Angiomatoid Fibrous (AFH) Categories: Cancer diseases, Genetic diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Histiocytoma, Angiomatoid Fibrous

MalaCards integrated aliases for Histiocytoma, Angiomatoid Fibrous:

Name: Histiocytoma, Angiomatoid Fibrous ⁵⁸ ⁷⁴

Angiomatoid Fibrous Histiocytoma ⁷⁶ ³⁰ ⁴¹

Histiocytoma, Angiomatoid Fibrous, Somatic ⁵⁸ ¹³

Afh ⁷⁶

Characteristics:

HPO:

³³

histiocytoma, angiomatoid fibrous:
Inheritance somatic mutation

Classifications:

MalaCards categories:
Global: Genetic diseases Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

OMIM ⁵⁸ 612160

MeSH ⁴⁵ D051677

MedGen ⁴³ C1266127

SNOMED-CT via HPO ⁷⁰ 124975008 128741006 302843004

UMLS ⁷⁴ C1266127

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Summaries for Histiocytoma, Angiomatoid Fibrous

UniProtKB/Swiss-Prot : ⁷⁶ Angiomatoid fibrous histiocytoma: A distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth. Characteristic microscopic features include lobulated sheets of histiocyte-like cells intimately associated with areas of hemorrhage and cystic pseudovascular spaces, as well as a striking cuffing of inflammatory cells, mimicking a lymph node metastasis.

MalaCards based summary : Histiocytoma, Angiomatoid Fibrous, also known as angiomatoid fibrous histiocytoma, is related to histiocytoma and fibrous histiocytoma. An important gene associated with Histiocytoma, Angiomatoid Fibrous is CREB1 (CAMP Responsive Element Binding Protein 1). The drugs Doxorubicin and Daunorubicin have been mentioned in the context of this disorder. Affiliated tissues include lymph node, bone and lung, and related phenotype is histiocytoma.

Wikipedia : ⁷⁷ Angiomatoid fibrous histiocytoma, abbreviated AFH, is a rarely metastasizing tumour that affects... more...

Description from OMIM: 612160

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Related Diseases for Histiocytoma, Angiomatoid Fibrous

Diseases related to Histiocytoma, Angiomatoid Fibrous via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)

#	Related Disease	Score
1	histiocytoma	10.4
2	fibrous histiocytoma	10.4
3	sarcoma	10.3
4	storage pool platelet disease	10.2
5	sarcoma, synovial	10.2
6	membranous nephropathy	10.2
7	granuloma annulare	10.2
8	angiosarcoma	10.2
9	melanoma	10.2
10	testicular cancer	10.2
11	spindle cell sarcoma	10.2
12	hard palate cancer	10.2
13	polyarteritis nodosa	10.2

Graphical network of the top 20 diseases related to Histiocytoma, Angiomatoid Fibrous:

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Symptoms & Phenotypes for Histiocytoma, Angiomatoid Fibrous

Human phenotypes related to Histiocytoma, Angiomatoid Fibrous:

³³

#	Description	HPO Frequency	HPO Source Accession
1	histiocytoma ³³		HP:0012315

Clinical features from OMIM:

612160

Sources

Drugs & Therapeutics for Histiocytoma, Angiomatoid Fibrous

Drugs for Histiocytoma, Angiomatoid Fibrous (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Doxorubicin

Approved, Investigational

Phase 2, Phase 3

23214-92-8

31703

Synonyms:

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside

(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-a-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S-cis)-10-((3-amino-2,3,6-Trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

111266-55-8

14-hydroxydaunomycin

14-Hydroxydaunomycin

14-hydroxydaunorubicine

14-Hydroxydaunorubicine

23214-92-8

23257-17-2

24385-08-8

25311-50-6

25316-40-9

25316-40-9 (hydrochloride)

29042-30-6

AC1L1M5T

AC1Q29OJ

adiblastine (hydrochloride salt)

ADM

ADR

adr iablatina (hydrochloride salt)

Adriablastin

Adriablastine

adriablastine (hydrochloride salt)

adriablatina (hydrochloride salt)

Adriacin (hydrochloride salt)

Adriamycin

Adriamycin PFS

Adriamycin PFS (hydrochloride salt)

Adriamycin RDF

Adriamycin RDF (hydrochloride salt)

Adriamycin semiquinone

Adriamycin Semiquinone

Adriblas tina

Adriblastin

Adriblastina

Adriblastina (hydrochloride salt)

Adriblastina (TN)

Adriblastine

adriblatina (hydrochloride salt)

Adrimedac

Aerosolized Doxorubicin

Baxter brand OF doxorubicin hydrochloride

Bedford brand OF doxorubicin hydrochloride

BPBio1_000502

BRD-K92093830-003-04-3

Bristol-myers squibb brand OF doxorubicin hydrochloride

BSPBio_000456

BSPBio_001031

C01661

C27H29NO11

Caelyx

CCRIS 739

Cell pharm brand OF doxorubicin hydrochloride

CHEBI:28748

CHEMBL179

CID31703

Columbia brand OF doxorubicin hydrochloride

Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74

Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120

D03899

DB00997

DM2

Doxil

Doxo

doxo Cell

doxo-Cell

Doxolem

doxorubicin

Doxorubicin

Doxorubicin (USAN/INN)

Doxorubicin [USAN:INN:BAN]

Doxorubicin citrate

Doxorubicin HCl

Doxorubicin hexal

Doxorubicin hydrochloride

Doxorubicin Hydrochloride

Doxorubicin hydrochloride (hydrochloride salt)

Doxorubicin NC

Doxorubicina

Doxorubicina [INN-Spanish]

Doxorubicina ferrer farm

Doxorubicina funk

Doxorubicina tedec

Doxorubicine

Doxorubicine [INN-French]

Doxorubicine baxter

Doxorubicin-hLL1

Doxorubicin-hLL1 conjugate

Doxorubicin-P4/D10

Doxorubicin-P4/D10 conjugate

Doxorubicinum

Doxorubicinum [INN-Latin]

Doxotec

DOX-SL

EINECS 245-495-6

Elan brand OF doxorubicin hydrochloride

Farmablastina (hydrochloride salt)

Farmiblastina

Ferrer brand OF doxorubicin hydrochloride

FI 106

Hexal brand OF doxorubicin hydrochloride

HMS2089H06

HSDB 3070

Hydrochloride, doxorubicin

Hydroxydaunomycin hydrochlor ide (hydrochloride salt)

Hydroxydaunomycin hydrochloride (hydrochloride salt)

Hydroxydaunorubicin

Hydroxydaunorubicin hydrochloride (hydrochloride salt)

JT9100000

Kenfarma brand OF doxorubicin hydrochloride

Lemery brand OF doxorubicin hydrochloride

LMPK13050001

LS-1029

LS-165655

Medac brand OF doxorubicin hydrochloride

MLS000759533

Myocet

NChemBio.2007.10-comp13

nchembio809-comp5

NCI-C01514

NDC 38242-874

Neocorp brand OF doxorubicin hydrochloride

NIOSH/JT9100000

NSC 123127

Onkodox

Onkoworks brand OF doxorubicin hydrochloride

Pfizer brand OF doxorubicin hydrochloride

Prasfarma brand OF doxorubicin hydrochloride

Prestwick0_000438

Prestwick1_000438

Prestwick2_000438

Prestwick3_000438

Probes1_000151

Probes2_000129

RDF Rubex

Resmycin

Ribodoxo

Ribosepharm brand OF doxorubicin hydrochloride

Rubex

Rubex (hydrochloride salt)

SMP1_000106

SPBio_002395

Tedec meiji brand OF doxorubicin hydrochloride

ThermoDox

TLC D-99

Triferric doxorubicin

UNII-80168379AG

Urokit doxo cell

Urokit doxo-cell

Daunorubicin

Approved

Phase 2, Phase 3

20830-81-3

30323

Synonyms:

(+)-Daunomycin

(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside

(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside

(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione

(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione

11006-54-5

11048-29-6

1407-15-4

149541-57-1

20830-81-3

23942-76-9

27576-81-4

28020-80-6

AB00514669

AC1L1JCP

AC1Q29OI

Acetyladriamycin

AI3-52942

Anthracyline

Antibiotics from Streptomyces coeruleorubidus

Antibiotics From Streptomyces Coeruleorubidus

BPBio1_000389

BRD-K43389675-003-02-7

BRN 1445583

BSPBio_000353

C01907

CCRIS 914

Cerubidin

Cerubidine

CHEBI:41977

CHEMBL178

CID30323

D07776

Daunamycin

Daunarubicinum

dauno Rubidomycine

Daunoblastin

Daunoblastine

Daunomycin

Daunomycin Hydrochloride

Daunomycin, Hydrochloride

Daunorrubicina

daunorubicin

Daunorubicin

Daunorubicin (INN)

Daunorubicin (liposomal)

Daunorubicin [INN:BAN]

Daunorubicin Hcl

DAUNORUBICIN HCL

Daunorubicin hydrochloride

Daunorubicin Hydrochloride

Daunorubicin, Hydrochloride

Daunorubicina

Daunorubicine

Daunorubicinum

Daunorubicinum [INN-Latin]

dauno-Rubidomycine

Dauno-Rubidomycine

Daunoxome

DaunoXome

DaunoXome (TN)

DB00694

DM1

EINECS 244-069-7

FI 6339

FI6339

HMS2089H04

HMS2091K06

HSDB 5095

Hydrochloride, daunorubicin

Leukaemomycin C

LMPK13050002

LS-187381

LS-997

MolPort-002-533-961

NCGC00024246-05

NCGC00024246-06

NCGC00025173-01

NChemBio.2007.10-comp14

nchembio723-comp2

NCI-C04693

NSC 83142

NSC-82151

Ondena

Prestwick3_000487

Rcra Waste No. U059

RCRA waste no. U059

RP 13057

Rp 13057 Hydrochloride

Rubidomycin

Rubidomycin Hydrochloride

Rubomycin

Rubomycin C

Tocris-1467

UNII-ZS7284E0ZP

VS-103

Ifosfamide

Approved

Phase 2, Phase 3

3778-73-2

3690

Synonyms:

(+-)-Ifosfamid

(+-)-Ifosphamide

(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

(D,L)-Ifosfamide

(R,S)-Ifosphamide

(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd

2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)

2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide

3,} 2-oxazaphosphorine oxide

36341-88-5

3778-73-2

84711-20-6

A 4942

AB00513932

AC1L1GHW

AC-2113

Ambap3778-73-2

Asta Z 4942

ASTA Z 4942

BPBio1_000865

BRN 0611835

BSPBio_000785

C07047

CAS-3778-73-2

CCRIS 352

CHEBI:5864

CHEMBL1024

CID3690

Cyfos

D00343

D007069

DB01181

EINECS 223-237-3

HMS1570H07

HMS2090M12

HMS2093N07

Holoxan

Holoxan 1000

HSDB 7023

I06-0494

Ifex

IFEX (TN)

Ifosfamid

Ifosfamida

Ifosfamida [INN-Spanish]

ifosfamide

Ifosfamide

Ifosfamide (JAN/USP/INN)

Ifosfamide [USAN:INN:BAN:JAN]

Ifosfamide sterile

Ifosfamide Sterile

Ifosfamidum

Ifosfamidum [INN-Latin]

Ifosphamide

Ifsofamide

Iphosphamid

Iphosphamid(e)

Iphosphamide

I-phosphamide

I-Phosphamide

iso Endoxan

Iso Endoxan

iso-Endoxan

Isoendoxan

Iso-Endoxan

Isofosfamide

Isophosphamide

isosfamide

Isosfamide

LS-102

LS-99799

Mitoxana

Mitoxana, Ifex, Ifosfamide

MJF 9325

MJF-9325

MLS002154021

MolPort-003-666-704

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid

N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide

N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide

N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine

N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide

Naxamide

NCGC00016639-01

NCGC00179435-01

NCI60_000233

NCI-C01638

NPFAPI-04

NSC 109,724

NSC 109724

NSC109,724

NSC-109,724

NSC109724

NSC-109724

Prestwick0_000833

Prestwick1_000833

Prestwick2_000833

Prestwick3_000833

S1302_Selleck

SMR001233348

SPBio_002706

STL058690

UNII-UM20QQM95Y

WLN: T6NPOTJ AM2G BO B2G

Z 4942

Z4942

Z-4942

Mechlorethamine

Approved, Investigational

Phase 2, Phase 3

51-75-2

4033

Synonyms:

.Beta.,.beta.'-Dichlorodiethyl-N-methylamine

1, 5-Dichloro-3-methyl-3-azapentane hydrochloride

126-85-2 (N-oxide)

2,2'-Dichlorodiethyl-methylamine

2,2'-Dichloro-N-me

2,2'-dichloro-N-methyldiethylamine

2,2'-dichloro-N-Methyldiethylamine

2,2'-Dichloro-N-methyldiethylamine

2-Chloro-N-(2-chloroethyl)-N-methylethanamine

302-70-5 (N-oxide, hydrochloride)

51-75-2

55-86-7 (HYDROCHLORIDE)

AC1L1H9H

Antimit

b,Beta'-dichlorodiethyl-N-methylamine

beta,beta'-Dichlorodiethyl-N-methylamine

beta,Beta'-dichlorodiethyl-N-methylamine

bis(2-chloroethyl)methylamine

Bis(2-chloroethyl)methylamine

Bis(b-chloroethyl)methylamine

Bis(beta-chloroethyl) methylamine

Bis(beta-chloroethyl)methylamine

bis(β-chloroethyl)methylamine

Bis(β-chloroethyl)methylamine

BRN 0605323

BSPBio_001947

C07115

C5H11Cl2N

Carolysine

Caryolysin

Caryolysine

CCRIS 447

CHEBI:28925

CHEMBL427

Chloramine (the nitrogen mustard)

Chlorethazine

Chlormethine

Chlormethine (INN)

Chlormethine [INN:BAN]

Chlormethinum

Chlormethinum [INN-Latin]

CID4033

Cloramin

Clormetina

Clormetina [INN-Spanish]

D07671

DB00888

Di(2-chloroethyl)methylamine

Dichlor amine

Dichloren

DivK1c_000759

EINECS 200-120-5

Embechine

Embichin

ENT-25294

HMS1920J15

HMS2091B04

HMS502F21

HN2

HN-2

HSDB 5083

Hydrochloride N-oxide, mechlorethamine

Hydrochloride, mechlorethamine

I14-8708

IBS-L0033631

IDI1_000759

KBio1_000759

KBio2_001369

KBio2_003937

KBio2_006505

KBio3_001447

KBioGR_001448

KBioSS_001369

LS-7559

MBA

Me chloroethamine

Mebichloramine

mechlorethamine

Mechlorethamine

Mechlorethamine hydrochloride

Mechlorethamine hydrochloride N oxide

Mechlorethamine hydrochloride N-oxide

Mechlorethamine N oxide

Mechlorethamine N-oxide

Mechlorethamine oxide

Mechlorethanamine

Mechloroethamine

Mecloretamina

Mecloretamina [Italian]

Merck brand OF mechlorethamine hydrochloride

Merck frosst brand OF mechlorethamine hydrochloride

methylbis(2-chloroethyl)amine

Methylbis(2-chloroethyl)amine

Methylbis(b-chloroethyl)amine

Methylbis(beta-chloroethyl)amine

methylbis(β-chloroethyl)amine

Methylbis(β-chloroethyl)amine

Methylchlorethamine

Methyldi(2-chloroethyl)amine

Mitomen

Mitoxine (*Hydrochloride*)

MolPort-001-785-592

Mustargen

Mustine

Mustine note

Mutagen

N,N-Bis(2-chloroethyl)methylamine

N,N-Bis(2-chloroethyl)-N-methylamine

N,N-Di(chloroethyl)methylamine

NCGC00091835-02

NCGC00091835-03

NCGC00091835-04

NCGC00091835-05

NCI60_041682

NINDS_000759

Nitol (*Hydrochloride*)

Nitrogen mustard

Nitrogen mustard (HN-2)

Nitrogen mustard N oxide

Nitrogen mustard N-oxide

Nitrogranulogen

Nitromin

N-Lost

N-Methyl lost

N-Methyl-2,2'-dichlorodiethylamine

N-methyl-bis(2-chloroethyl)amine

N-Methyl-bis(2-chloroethyl)amine

N-Methyl-bis(b-chloroethyl)amine

N-Methyl-bis(beta-chloroethyl)amine

N-methyl-bis(β-chloroethyl)amine

N-Methyl-bis(β-chloroethyl)amine

N-Methyl-bis-chloraethylamin

N-Methyl-bis-chloraethylamin [German]

N-Methyl-lost

N-Methyl-lost [German]

N-Oxide, mechlorethamine hydrochloride

N-Oxide, nitrogen mustard

NSC 762

NSC762

NSC-762

SPBio_000496

Spectrum_000889

SPECTRUM1500375

Spectrum2_000448

Spectrum3_000484

Spectrum4_000924

Spectrum5_001702

Stickstofflost (*Hydrochloride*)

Stickstofflost (ebewe)

T 1024

T-1024

thyldiethylamine

TL 146

UNII-50D9XSG0VR

β,beta'-dichlorodiethyl-N-methylamine

β,β'-dichlorodiethyl-N-methylamine

Cyclophosphamide

Approved, Investigational

Phase 2, Phase 3

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CPA

CTX

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

Doxil

Approved June 1999

Phase 2, Phase 3

31703

Topoisomerase Inhibitors

Phase 2, Phase 3

Antineoplastic Agents, Alkylating

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3

Antibiotics, Antitubercular

Phase 2, Phase 3

Alkylating Agents

Phase 2, Phase 3

Isophosphamide mustard

Phase 2, Phase 3

Synonyms:

Ifosfamide mustard

Ifosforamide mustard

IPAM

Iphosphoramide mustard

Isophosphamide mustard

Isophosphoramide mustard

N,N'-di-(2-chloroethyl)phosphorodiamidic acid

NN'-Bis-(2-chloroethyl)phosphate

NN'-Bis-(2-chloroethyl)phosphoric acid

Palifosfamide-tris

zio-201Isophosphamide mustard

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery	Active, not recruiting	NCT02180867	Phase 2, Phase 3	Doxorubicin;Doxorubicin Hydrochloride;Ifosfamide;Pazopanib;Pazopanib Hydrochloride
2	Angiomatoid Fibrous Histiocytoma: a Single Institution Case-series	Not yet recruiting	NCT03759327

Search NIH Clinical Center for Histiocytoma, Angiomatoid Fibrous

Sources

Genetic Tests for Histiocytoma, Angiomatoid Fibrous

Genetic tests related to Histiocytoma, Angiomatoid Fibrous:

#	Genetic test	Affiliating Genes
1	Angiomatoid Fibrous Histiocytoma ³⁰	CREB1

Sources

Anatomical Context for Histiocytoma, Angiomatoid Fibrous

MalaCards organs/tissues related to Histiocytoma, Angiomatoid Fibrous:

⁴²

Lymph Node, Bone, Lung, Skin

Sources

Publications for Histiocytoma, Angiomatoid Fibrous

Articles related to Histiocytoma, Angiomatoid Fibrous:

(show top 50) (show all 92)

#	Title	Authors	Year
1	Hybrid bronchoscopic and surgical resection of endotracheal angiomatoid fibrous histiocytoma. ( 30819218 )	Bouma W...Klinkenberg TJ	2019
2	Primary Adrenal Angiomatoid Fibrous Histiocytoma With Novel EWSR1-ATF1 Gene Fusion Exon-Exon Breakpoint. ( 30823861 )	Khan IS...Tou-En Chang K	2019
3	Intracranial angiomatoid fibrous histiocytoma with EWSR1-CREB family fusions: a report of two pediatric cases. ( 30831299 )	Konstantinidis A...Kilday JP	2019
4	A case of childhood intracerebral angiomatoid fibrous histiocytoma radiologically mimicking infection and with unusual immunopositivity for placental alkaline phosphatase. ( 30990406 )	Aizpurua M...King A	2019
5	ALK Expression in Angiomatoid Fibrous Histiocytoma: Confirmation of the Findings of Cheah et al. ( 31021856 )	Van Zwam P...Flucke U	2019
6	TLE-1-Positive Angiomatoid Fibrous Histiocytoma Mimicking Synovial Sarcoma. ( 28248724 )	Zaccarini DJ...Curtiss CM	2019
7	Angiomatoid fibrous histiocytoma of the scalp mimicking cutaneous angiosarcoma in incisional biopsy containing CD31-positive histiocytes: A potential histopathological pitfall. ( 28370384 )	Kanameishi S...Kabashima K	2018
8	Retroperitoneal Angiomatoid Fibrous Histiocytoma Presenting as a Recurrent Spontaneous Retroperitoneal Hemorrhage in a 9-Year-Old Boy. ( 29432314 )	Slack JC...Br?ndler MA	2018
9	Angiomatoid Fibrous Histiocytoma With Paraneoplastic Platelet Storage Pool Deficiency. ( 29472492 )	Morgan LM...Elster JD	2018
10	Primary intracranial angiomatoid fibrous histiocytoma: a case report and literature review. ( 29540076 )	Spatz M...Nussbaum LA	2018
11	A Case of Angiomatoid Fibrous Histiocytoma Presenting as Subcutaneous Nodule in a 4-Year-Old Girl. ( 29606824 )	Kang HJ...Lee WJ	2018
12	ESWR1-CREM Fusion in an Intracranial Myxoid Angiomatoid Fibrous Histiocytoma-Like Tumor: A Case Report and Literature Review. ( 29788195 )	Gareton A...Varlet P	2018
13	ALK Expression in Angiomatoid Fibrous Histiocytoma: A Potential Diagnostic Pitfall. ( 29877921 )	Cheah AL...Goldblum JR	2018
14	Therapeutic response of metastatic angiomatoid fibrous histiocytoma carrying EWSR1-CREB1 fusion to the interleukin-6 receptor antibody tocilizumab. ( 29932283 )	Potter SL...Venkatramani R	2018
15	Treatment of angiomatoid fibrous histiocytoma after unplanned excision: a case report. ( 30170609 )	Hashimoto K...Akagi M	2018
16	Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? ( 28281318 )	Bale TA...Alexandrescu S	2018
17	Angiomatoid fibrous histiocytoma: A case of local recurrence and metastases to loco-regional lymph nodes that responded to chemotherapy. ( 28012233 )	Ogden S...Pizer B	2017
18	Angiomatoid fibrous histiocytoma: a series of seven cases including genetically confirmed aggressive cases and a literature review. ( 28114920 )	Saito K...Chuman H	2017
19	Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28536856 )	Ulaner GA...Athanasian EA	2017
20	CORR Insights®: Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28656494 )	Morawietz L	2017
21	Angiomatoid fibrous histiocytoma: novel MR imaging findings. ( 26919861 )	Martinez SJ...Brigman BE	2016
22	Angiomatoid fibrous histiocytoma: Clinicopathological spectrum of five cases, including EWSR1-CREB1 positive result in a single case. ( 27166030 )	Rekhi B...Jambhekar NA	2016
23	Primary angiomatoid fibrous histiocytoma of the lung with mediastinal lymph node metastasis. ( 27544801 )	Tay CK...Folpe AL	2016
24	'Pure' spindle cell variant of angiomatoid fibrous histiocytoma, lacking classic histologic features. ( 27637157 )	Thway K...Fisher C	2016
25	Intracranial Angiomatoid Fibrous Histiocytoma: Case Report and Literature Review. ( 27667574 )	Alshareef MA...Vandergrift WA	2016
26	Characterization of metastatic angiomatoid fibrous histiocytoma. ( 25757019 )	Maher OM...Herzog CE	2015
27	Angiomatoid fibrous histiocytoma: comparison of fluorescence in situ hybridization and reverse transcription polymerase chain reaction as adjunct diagnostic modalities. ( 25804255 )	Thway K...Fisher C	2015
28	Primary intracranial angiomatoid fibrous histiocytoma presenting with anaemia and migraine-like headaches and aura as early clinical features. ( 25900984 )	Hansen JM...Skj?th-Rasmussen J	2015
29	Angiomatoid fibrous histiocytoma - case series with emphasis on a late fibrotic variant. ( 25918088 )	Wilk M...Zelger B	2015
30	Angiomatoid fibrous histiocytoma: the current status of pathology and genetics. ( 25927151 )	Thway K...Fisher C	2015
31	Imaging of childhood angiomatoid fibrous histiocytoma with pathological correlation. ( 26162466 )	Yikilmaz A...Navarro OM	2015
32	Paraneoplastic Syndrome of Angiomatoid Fibrous Histiocytoma May Be Caused by EWSR1-CREB1 Fusion-induced Excessive Interleukin-6 Production. ( 26165403 )	Akiyama M...Matsumoto K	2015
33	Angiomatoid fibrous histiocytoma: case report and review of the literature. ( 26613231 )	Tataro?lu C...?e?en E	2015
34	Angiomatoid Fibrous Histiocytoma With Prominent Myxoid Stroma: A Case Report and Review of the Literature. ( 25406850 )	Justin Wong SB...Lee VK	2015
35	Clinicopathological features of angiomatoid fibrous histiocytoma: a series of 21 cases with variant morphology. ( 25755773 )	Shi H...Han A	2015
36	Solid variant of angiomatoid fibrous histiocytoma masked by interstitial granuloma annulare in a 13-year-old child: no evidence for translocation breakpoints. ( 24002209 )	Kaune KM...Bertsch HP	2014
37	Angiomatoid fibrous histiocytoma: clinicopathological and molecular characterisation with emphasis on variant histomorphology. ( 24043718 )	Kao YC...Huang HY	2014
38	At the intersection of primary pulmonary myxoid sarcoma and pulmonary angiomatoid fibrous histiocytoma: observations from three new cases. ( 24372335 )	Smith SC...Myers JL	2014
39	A case report: angiomatoid fibrous histiocytoma in a 6-year-old male and review of the literature. ( 24521435 )	Kaygusuz EI...Celayir A	2014
40	Angiomatoid fibrous histiocytoma: an expansion of the clinical and histological spectrum. ( 24614712 )	Bohman SL...Billings SD	2014
41	Angiomatoid fibrous histiocytoma of the pulmonary artery: a multidisciplinary discussion. ( 24702653 )	Ghigna MR...Thomas-de-Montpreville V	2014
42	Ultrasound B-mode and elastographic findings of angiomatoid fibrous histiocytoma. ( 24758358 )	Hata H...Shimizu H	2014
43	Membranous nephropathy associated with angiomatoid fibrous histiocytoma in a pediatric patient. ( 24880818 )	Kohorst MA...Arndt CA	2014
44	Recurrent angiomatoid fibrous histiocytoma: a case report and review of the literature. ( 25249813 )	Huerter ME...Riker AI	2014
45	Recurrent painful perianal subcutaneous angiomatoid fibrous histiocytoma: a case report and review of the literature. ( 25526437 )	Kong X...Cui Q	2014
46	Retroperitoneal angiomatoid fibrous histiocytoma: A case report and review of the literature. ( 23833650 )	Xiang L...Yang B	2013
47	Angiomatoid fibrous histiocytoma as a second tumor in a young adult with testicular cancer. ( 24155684 )	Lee HS...Yi SY	2013
48	Metastatic angiomatoid fibrous histiocytoma of the scalp, with EWSR1-CREB1 gene fusions in primary tumor and nodal metastasis. ( 23199525 )	Thway K...Fisher C	2013
49	Subcutaneous angiomatoid fibrous histiocytoma mimicking metastatic melanoma. ( 23320232 )	Sparreboom E...Blokx W	2012
50	Angiomatoid fibrous histiocytoma: a case report and review of the literature. ( 23372863 )	Bauer A...Gilbertson-Dahdal D	2012

Sources

Genes for Histiocytoma, Angiomatoid Fibrous

Genes related to Histiocytoma, Angiomatoid Fibrous (1 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	600	Molecular basis known ⁵⁸ Genetic Tests ³⁰

Sources

Variations for Histiocytoma, Angiomatoid Fibrous

Sources

Expression for Histiocytoma, Angiomatoid Fibrous

Search GEO for disease gene expression data for Histiocytoma, Angiomatoid Fibrous.

Sources

Pathways for Histiocytoma, Angiomatoid Fibrous

Sources

GO Terms for Histiocytoma, Angiomatoid Fibrous

Sources

Sources for Histiocytoma, Angiomatoid Fibrous

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia

Histiocytoma, Angiomatoid Fibrous (AFH)

Aliases & Classifications for Histiocytoma, Angiomatoid Fibrous

MalaCards integrated aliases for Histiocytoma, Angiomatoid Fibrous:

Characteristics:

HPO:

Classifications:

External Ids:

Summaries for Histiocytoma, Angiomatoid Fibrous

Related Diseases for Histiocytoma, Angiomatoid Fibrous

Diseases related to Histiocytoma, Angiomatoid Fibrous via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Histiocytoma, Angiomatoid Fibrous:

Symptoms & Phenotypes for Histiocytoma, Angiomatoid Fibrous

Human phenotypes related to Histiocytoma, Angiomatoid Fibrous:

Clinical features from OMIM:

Drugs & Therapeutics for Histiocytoma, Angiomatoid Fibrous

Drugs for Histiocytoma, Angiomatoid Fibrous (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Genetic Tests for Histiocytoma, Angiomatoid Fibrous

Genetic tests related to Histiocytoma, Angiomatoid Fibrous:

Anatomical Context for Histiocytoma, Angiomatoid Fibrous

MalaCards organs/tissues related to Histiocytoma, Angiomatoid Fibrous:

Publications for Histiocytoma, Angiomatoid Fibrous

Articles related to Histiocytoma, Angiomatoid Fibrous:

Genes for Histiocytoma, Angiomatoid Fibrous

Genes related to Histiocytoma, Angiomatoid Fibrous (1 elite genes):

Variations for Histiocytoma, Angiomatoid Fibrous

Expression for Histiocytoma, Angiomatoid Fibrous

Pathways for Histiocytoma, Angiomatoid Fibrous

GO Terms for Histiocytoma, Angiomatoid Fibrous

Sources for Histiocytoma, Angiomatoid Fibrous