MCID: HBN001
MIFTS: 22

Hobnail Hemangioma

Categories: Cancer diseases

Aliases & Classifications for Hobnail Hemangioma

MalaCards integrated aliases for Hobnail Hemangioma:

Name: Hobnail Hemangioma 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:505
UMLS 72 C0346076

Summaries for Hobnail Hemangioma

MalaCards based summary : Hobnail Hemangioma is related to hemangioendothelioma and angiosarcoma. An important gene associated with Hobnail Hemangioma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways are Angiogenesis (CST) and Cell adhesion_Endothelial cell contacts by non-junctional mechanisms. Related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Hobnail Hemangioma

Diseases related to Hobnail Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 hemangioendothelioma 31.2 PECAM1 FLT4
2 angiosarcoma 30.9 PECAM1 FLT4
3 lymphangioma 30.4 PDPN FLT4
4 hemangioma 29.8 PECAM1 PDPN FLT4 CD34
5 vascular cancer 29.4 FLT4 CD34
6 kaposi sarcoma 10.5
7 retiform hemangioendothelioma 10.4
8 lymphatic malformations 10.4
9 wilms tumor 1 10.3
10 wilms tumor 5 10.3
11 orbital lymphangioma 10.2 PDPN FLT4
12 hydrocele 10.2 PECAM1 FLT4
13 congenital lymphedema 10.1 PDPN FLT4
14 human herpesvirus 8 10.1
15 histiocytoma 10.1
16 fibrous histiocytoma 10.1
17 exophthalmos 10.1
18 cavernous lymphangioma 10.1
19 rare lymphatic malformation 10.1
20 pneumatosis cystoides intestinalis 10.0 WT1 PDPN
21 diffuse peritoneal leiomyomatosis 9.9 WT1 CD34
22 peritoneal benign neoplasm 9.9 WT1 CD34
23 erythema elevatum diutinum 9.9 PECAM1 CD34
24 venous hemangioma 9.9 WT1 CD34
25 malignant epithelioid hemangioendothelioma 9.9 FLT4 CD34
26 adult fibrosarcoma 9.8 WT1 CD34
27 spindle cell liposarcoma 9.8 WT1 CD34
28 pediatric angiosarcoma 9.8 F8 CD34
29 spleen cancer 9.8 F8 CD34
30 interstitial emphysema 9.8 FLT4 CD34
31 atypical neurofibroma 9.8 PDPN CD34
32 alveoli adenoma 9.8 FLT4 CD34
33 breast angiosarcoma 9.8 F8 CD34
34 malignant hemangioma 9.6 FLT4 CD34
35 nephrogenic adenofibroma 9.6 WT1 CD34
36 benign perivascular tumor 9.6 PDPN CD34
37 cardiovascular organ benign neoplasm 9.6 PDPN CD34
38 muscle cancer 9.6 WT1 CD34
39 mesothelioma, malignant 9.6 WT1 PDPN
40 kaposiform hemangioendothelioma 9.5 PECAM1 FLT4 CD34
41 lymphangiosarcoma 8.9 PDPN FLT4 F8 CD34

Graphical network of the top 20 diseases related to Hobnail Hemangioma:



Diseases related to Hobnail Hemangioma

Symptoms & Phenotypes for Hobnail Hemangioma

MGI Mouse Phenotypes related to Hobnail Hemangioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 ACTB CD34 F8 PDPN PECAM1 WT1
2 homeostasis/metabolism MP:0005376 9.8 ACTB CD34 F8 FLT4 PDPN PECAM1
3 cardiovascular system MP:0005385 9.77 ACTB FLT4 PDPN PECAM1 WT1
4 immune system MP:0005387 9.7 ACTB CD34 F8 FLT4 PDPN PECAM1
5 liver/biliary system MP:0005370 9.26 ACTB FLT4 PECAM1 WT1
6 muscle MP:0005369 9.02 ACTB FLT4 PDPN PECAM1 WT1

Drugs & Therapeutics for Hobnail Hemangioma

Search Clinical Trials , NIH Clinical Center for Hobnail Hemangioma

Genetic Tests for Hobnail Hemangioma

Anatomical Context for Hobnail Hemangioma

Publications for Hobnail Hemangioma

Articles related to Hobnail Hemangioma:

(show all 28)
# Title Authors PMID Year
1
Orbital Hobnail Hemangioma. 38
29494379 2018
2
Hobnail Hemangioma With an Unusual Clinical Presentation. 38
27708135 2017
3
Arborizing vessels in a targetoid hemosiderotic hemangioma: mistaken dermoscopic diagnosis of basal cell carcinoma. 38
28243494 2017
4
Contributions of Dr. Juan Rosai to the pathology of cutaneous vascular proliferations: A review of selected lesions. 38
27318413 2016
5
Hobnail Hemangioma (Superficial Hemosiderotic Lymphovascular Malformation) in Children: A Series of 6 Pediatric Cases and Review of the Literature. 38
26475078 2016
6
Hobnail Hemangioma: A Case Report. 38
26156669 2015
7
Targetoid hemosiderotic hemangioma - Case report. 38
25387500 2014
8
Superficial hemosiderotic lymphovascular malformation (hobnail hemangioma): a report of six cases. 38
24601986 2014
9
Oral hobnail hemangioma: a case report. 38
23808782 2013
10
Hobnail hemangioma on the trunk. 38
24011279 2013
11
Targetoid hemosiderotic hemangioma (Hobnail Hemangioma): typical clinical and histological presentation. 38
24033978 2013
12
Hobnail hemangioma: a immunohistochemical study and literature review. 38
23161236 2012
13
Hobnail hemangioma. 38
22864784 2012
14
A cutaneous vascular neoplasm with hobnail microscopic morphology and unusual gross features. 38
22097956 2012
15
Targetoid hemosiderotic hemangiomas (hobnail hemangiomas) are vascular lymphatic malformations: a study of 12 pediatric cases. 38
21798621 2012
16
Hobnail hemangioma reclassified as superficial lymphatic malformation: a study of 52 cases. 38
21821311 2012
17
Congenital and multiple hobnail hemangiomas. 38
22148030 2011
18
Hobnail hemangioma in a nine-year-old boy: a rare case presented with dermoscopy. 38
20409414 2010
19
Oral hobnail hemangioma: case report. 38
20027132 2009
20
Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma. 38
19606014 2009
21
Oral hobnail hemangioma--a case report. 38
19057748 2008
22
Clinical changes in "true" hobnail hemangioma during menstruation. 38
18517139 2008
23
Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas. 38
15059220 2004
24
Immunostaining for human herpesvirus 8 latent nuclear antigen-1 helps distinguish Kaposi sarcoma from its mimickers. 38
15023037 2004
25
Absence of HHV-8 DNA in hobnail hemangiomas. 38
11972712 2002
26
Hobnail hemangioma ("targetoid hemosiderotic hemangioma"): clinicopathologic and immunohistochemical analysis of 62 cases. 38
10472756 1999
27
Hobnail hemangioma: a pseudomalignant vascular lesion with a reappraisal of targetoid hemosiderotic hemangioma. 38
9888709 1999
28
Hobnail hemangioma. 38
8520065 1995

Variations for Hobnail Hemangioma

Expression for Hobnail Hemangioma

Search GEO for disease gene expression data for Hobnail Hemangioma.

Pathways for Hobnail Hemangioma

Pathways related to Hobnail Hemangioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.75 PECAM1 PDPN FLT4
2 10.56 PECAM1 ACTB

GO Terms for Hobnail Hemangioma

Cellular components related to Hobnail Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.43 PECAM1 PDPN FLT4 F8 CD34 ACTB
2 cell periphery GO:0071944 8.62 PECAM1 CD34

Biological processes related to Hobnail Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Rho protein signal transduction GO:0007266 9.26 PECAM1 PDPN
2 cell motility GO:0048870 9.16 CD34 ACTB
3 lymphangiogenesis GO:0001946 8.96 PDPN FLT4
4 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Hobnail Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....