MCID: HDG003
MIFTS: 36

Hodgkin's Lymphoma, Lymphocytic Depletion

Categories: Blood diseases, Cancer diseases, Immune diseases, Rare diseases

Aliases & Classifications for Hodgkin's Lymphoma, Lymphocytic Depletion

MalaCards integrated aliases for Hodgkin's Lymphoma, Lymphocytic Depletion:

Name: Hodgkin's Lymphoma, Lymphocytic Depletion 12 15
Hodgkin's Lymphocytic Depletion of Unspecified Site 12
Classic Hodgkin Lymphoma, Lymphocyte-Depleted Type 59
Lymphocyte-Depleted Classical Hodgkin Lymphoma 12
Hodgkin's Disease, Lymphocytic Depletion 12
Hodgkin Lymphoma, Lymphocyte Depletion 12

Characteristics:

Orphanet epidemiological data:

59

Classifications:



External Ids:

Disease Ontology 12 DOID:8628
ICD10 33 C81.3
ICD9CM 35 201.7
MeSH 44 D006689
NCIt 50 C9283
Orphanet 59 ORPHA98846
UMLS via Orphanet 74 C0152267
ICD10 via Orphanet 34 C81.3
UMLS 73 C0152267

Summaries for Hodgkin's Lymphoma, Lymphocytic Depletion

MalaCards based summary : Hodgkin's Lymphoma, Lymphocytic Depletion, also known as hodgkin's lymphocytic depletion of unspecified site, is related to lymphoma, hodgkin, classic and hodgkin's granuloma. An important gene associated with Hodgkin's Lymphoma, Lymphocytic Depletion is POU2AF1 (POU Class 2 Associating Factor 1), and among its related pathways/superpathways are NF-kappaB Signaling and Wnt / Hedgehog / Notch. Affiliated tissues include lung, brain and colon, and related phenotypes are hematopoietic system and immune system

Related Diseases for Hodgkin's Lymphoma, Lymphocytic Depletion

Diseases related to Hodgkin's Lymphoma, Lymphocytic Depletion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 lymphoma, hodgkin, classic 31.6 ALK CD79A PAX5 PTPRC
2 hodgkin's granuloma 10.6
3 gray zone lymphoma 10.2 CD79A PAX5
4 bladder lymphoma 10.2 CD79A PAX5
5 primary cutaneous anaplastic large cell lymphoma 10.2 ALK PTPRC
6 small intestine lymphoma 10.1 CD79A PTPRC
7 viral esophagitis 10.1 CD68 CD79A
8 nodular tenosynovitis 10.1 CD68 PTPRC
9 extracutaneous mastocytoma 10.1 CD68 PTPRC
10 malignant giant cell tumor of soft parts 10.1 CD68 PTPRC
11 lymphoplasmacyte-rich meningioma 10.1 CD68 CD79A
12 brain sarcoma 10.1 CD68 PTPRC
13 plasma cell neoplasm 10.1 CD79A PTPRC
14 gamma heavy chain disease 10.1 FUT4 PTPRC
15 myeloid sarcoma 10.1 PAX5 PTPRC
16 glomeruloid hemangioma 10.1 CD68 PTPRC
17 lymphoma 10.1
18 trigeminal nerve neoplasm 10.1 CD68 PTPRC
19 neurilemmoma of the fifth cranial nerve 10.1 CD68 PTPRC
20 lymphosarcoma 10.1 CD79A PTPRC
21 photokeratitis 10.1 CD68 PTPRC
22 alk+ histiocytosis 10.1 ALK FSCN1
23 ulcerative stomatitis 10.1 CD68 CD79A
24 granulomatous gastritis 10.1 CD68 FUT4
25 adult xanthogranuloma 10.1 CD68 FUT4
26 aleukemic leukemia cutis 10.0 CD68 FUT4
27 mature b-cell neoplasm 10.0 CD79A PTPRC
28 malignant leydig cell tumor 10.0 PAX5 TNFRSF8
29 hemangioma of intra-abdominal structure 10.0 CD68 FUT4
30 reticulum cell sarcoma 10.0 PTPRC TNFRSF8
31 colloid carcinoma of the pancreas 10.0 FSCN1 FSCN3
32 melkersson-rosenthal syndrome 10.0 CD68 PTPRC
33 thymus lipoma 10.0 PTPRC TNFRSF8
34 adult lymphoma 10.0 ALK TNFRSF8
35 immune system organ benign neoplasm 9.9 PTPRC TNFRSF8
36 lichen nitidus 9.9 CD68 TNFRSF8
37 t-cell/histiocyte rich large b cell lymphoma 9.9 CD68 TNFRSF8
38 granulomatous myositis 9.9 CD68 TNFRSF8
39 dendritic cell tumor 9.9 CD68 FSCN1 PTPRC
40 pediatric lymphoma 9.9 ALK CD79A TNFRSF8
41 follicular mucinosis 9.9 PTPRC TNFRSF8
42 histiocytosis 9.9 CSF2 PTPRC TNFRSF8
43 ecthyma 9.9 ALK CSF2 TNFRSF8
44 testicular infarct 9.9 FUT4 PTPRC TNFRSF8
45 epidural neoplasm 9.9 FUT4 PTPRC TNFRSF8
46 conventional fibrosarcoma 9.8 CD68 PTPRC TNFRSF8
47 lung lymphoma 9.8 ALK CD79A PAX5 TNFRSF8
48 reticulosarcoma 9.8 ALK PAX5 PTPRC TNFRSF8
49 anaplastic large cell lymphoma 9.8 ALK PAX5 PTPRC TNFRSF8
50 colon lymphoma 9.8 ALK CD79A PTPRC TNFRSF8

Graphical network of the top 20 diseases related to Hodgkin's Lymphoma, Lymphocytic Depletion:



Diseases related to Hodgkin's Lymphoma, Lymphocytic Depletion

Symptoms & Phenotypes for Hodgkin's Lymphoma, Lymphocytic Depletion

MGI Mouse Phenotypes related to Hodgkin's Lymphoma, Lymphocytic Depletion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.76 CD68 CD79A CSF2 FUT4 PAX5 POU2AF1
2 immune system MP:0005387 9.61 CD68 CD79A CSF2 FSCN1 FUT4 PAX5
3 neoplasm MP:0002006 9.02 ALK CD79A CSF2 PAX5 PTPRC

Drugs & Therapeutics for Hodgkin's Lymphoma, Lymphocytic Depletion

Search Clinical Trials , NIH Clinical Center for Hodgkin's Lymphoma, Lymphocytic Depletion

Genetic Tests for Hodgkin's Lymphoma, Lymphocytic Depletion

Anatomical Context for Hodgkin's Lymphoma, Lymphocytic Depletion

MalaCards organs/tissues related to Hodgkin's Lymphoma, Lymphocytic Depletion:

41
Lung, Brain, Colon, Pancreas, B Cells, Thymus, Small Intestine

Publications for Hodgkin's Lymphoma, Lymphocytic Depletion

Variations for Hodgkin's Lymphoma, Lymphocytic Depletion

Expression for Hodgkin's Lymphoma, Lymphocytic Depletion

Search GEO for disease gene expression data for Hodgkin's Lymphoma, Lymphocytic Depletion.

Pathways for Hodgkin's Lymphoma, Lymphocytic Depletion

Pathways related to Hodgkin's Lymphoma, Lymphocytic Depletion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 CD79A PAX5 PTPRC TNFRSF8
2 11.69 FSCN1 FUT4 PAX5
3 10.99 CD68 CD79A CSF2 PTPRC
4 10.89 CD79A PTPRC
5 10.86 PAX5 PTPRC TNFRSF8

GO Terms for Hodgkin's Lymphoma, Lymphocytic Depletion

Biological processes related to Hodgkin's Lymphoma, Lymphocytic Depletion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin filament bundle assembly GO:0051017 9.37 FSCN1 FSCN3
2 establishment or maintenance of cell polarity GO:0007163 9.32 FSCN1 FSCN3
3 B cell proliferation GO:0042100 9.26 CD79A PTPRC
4 adult behavior GO:0030534 9.16 ALK PAX5
5 positive regulation of podosome assembly GO:0071803 8.96 CSF2 FSCN1
6 regulation of B cell receptor signaling pathway GO:0050855 8.62 PAX5 PTPRC

Molecular functions related to Hodgkin's Lymphoma, Lymphocytic Depletion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.8 ALK CD79A TNFRSF8

Sources for Hodgkin's Lymphoma, Lymphocytic Depletion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....