MCID: HDG002
MIFTS: 47

Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Categories: Blood diseases, Cancer diseases, Immune diseases

Aliases & Classifications for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

MalaCards integrated aliases for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:

Name: Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance 12 15
Hodgkin Disease 44 73
Hodgkin Lymphoma, Lymphocytic-Histiocytic Predominance 12
Hodgkin's Disease, Lymphocyte Predominance 12
Lymphocyte Rich Classical Hodgkin Lymphoma 73
Hodgkin Lymphoma, Lymphocyte-Rich 12
Lymphocyte Rich Hodgkin's Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8543
ICD10 33 C81.4
ICD9CM 35 201.4
MeSH 44 D006689
NCIt 50 C6913
SNOMED-CT 68 59668005

Summaries for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

MalaCards based summary : Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance, also known as hodgkin disease, is related to lymphoma, hodgkin, classic and lymphoma, non-hodgkin, familial, and has symptoms including fever and night sweats. An important gene associated with Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance is B3GAT1 (Beta-1,3-Glucuronyltransferase 1), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and B cell receptor signaling pathway (KEGG). Affiliated tissues include bone, t cells and bone marrow, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Diseases related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 148)
# Related Disease Score Top Affiliating Genes
1 lymphoma, hodgkin, classic 33.2 BCL6 PTPRC
2 lymphoma, non-hodgkin, familial 29.9 BCL6 CR2 PTPRC
3 follicular lymphoma 29.3 BCL6 CR2
4 castleman disease 29.1 BCL6 CR2
5 leukemia, chronic lymphocytic 28.8 BCL6 CR2 PTPRC
6 classic hodgkin lymphoma, lymphocyte-rich type 12.7
7 lymphoma, hodgkin, x-linked pseudoautosomal 11.3
8 lymphoma 11.3
9 lymphoproliferative syndrome 1 11.1
10 sarcoidosis 1 11.0
11 lymphoma, hodgkin, y-linked pseudoautosomal 11.0
12 hodgkin's paragranuloma 11.0
13 hodgkin's granuloma 11.0
14 kidney rhabdoid cancer 10.1 B3GAT1 PTPRC
15 gastric small cell carcinoma 10.1 B3GAT1 PTPRC
16 bone ewing's sarcoma 10.1 B3GAT1 PTPRC
17 heart lymphoma 10.1 BCL6 PTPRC
18 testicular lymphoma 10.1 BCL6 PTPRC
19 colon lymphoma 10.1 BCL6 PTPRC
20 epidural neoplasm 10.1 BCL6 PTPRC
21 plasmablastic lymphoma 10.1 BCL6 PTPRC
22 leukemia 10.0
23 testicular infarct 10.0 PHYH PTPRC
24 lymphosarcoma 10.0 BCL6 PTPRC
25 mature b-cell neoplasm 10.0 BCL6 PTPRC
26 reticulosarcoma 10.0 BCL6 PTPRC
27 liver inflammatory pseudotumor 10.0 CR2 PTPRC
28 interdigitating dendritic cell sarcoma 10.0 CR2 PTPRC
29 ovarian lymphoma 10.0 CR2 PTPRC
30 histiocytic and dendritic cell cancer 10.0 CR2 PTPRC
31 reticulum cell sarcoma 9.9 CR2 PTPRC
32 lymphoblastic lymphoma 9.9 BCL6 PTPRC
33 ataxia-telangiectasia 9.9
34 dendritic cell tumor 9.9 CR2 PTPRC
35 t-cell/histiocyte rich large b cell lymphoma 9.9 BCL6 CR2
36 hodgkin's lymphoma, mixed cellularity 9.9 B3GAT1 PHYH PTPRC
37 lung lymphoma 9.9 BCL6 CR2
38 lymphatic system cancer 9.9 BCL6 PHYH PTPRC
39 breast cancer 9.8
40 anaplastic large cell lymphoma 9.8
41 hemolytic anemia 9.8
42 purpura 9.8
43 cerebellar degeneration 9.8
44 mantle cell lymphoma 9.8 BCL6 PTPRC
45 b-cell lymphomas 9.8
46 common variable immunodeficiency 9.8
47 thrombocytopenia 9.8
48 lymphocytic leukemia 9.8
49 sarcoma 9.8
50 nephrotic syndrome 9.8

Graphical network of the top 20 diseases related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:



Diseases related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Symptoms & Phenotypes for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

UMLS symptoms related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:


fever, night sweats

MGI Mouse Phenotypes related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.43 BCL6 CR2 ERF PHYH PKP1 PTPRC
2 mortality/aging MP:0010768 9.1 B3GAT1 BCL6 CR2 ERF PKP1 PTPRC

Drugs & Therapeutics for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Genetic Tests for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Anatomical Context for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

MalaCards organs/tissues related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:

41
Bone, T Cells, Bone Marrow, B Cells, Breast, Lung, Brain

Publications for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Articles related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance:

(show top 50) (show all 569)
# Title Authors Year
1
Granulomatous Lymphangitis Masquerading as Relapsed Hodgkin Disease on FDG PET/CT. ( 30042982 )
2018
2
Utility of Routine Surveillance Imaging for Hodgkin Disease following Autologous Transplant: Experiences from a Single Institution. ( 29339629 )
2018
3
Idiopathic Thrombocytopenia Purpura Masking Hodgkin Disease: A Paraneoplastic Syndrome or Simply a Mere Association? ( 29430236 )
2017
4
Prolonged Rhinovirus Shedding in a Patient with Hodgkin Disease. ( 28137315 )
2017
5
Web Exclusives. Annals Consult Guys - The Adult Survivor of Hodgkin Disease: Falling Through the Cracks. ( 28505658 )
2017
6
Acquired reactive perforating collagenosis associated with Hodgkin disease. ( 28691303 )
2017
7
Radiotherapy changes salivary properties and impacts quality of life of children with Hodgkin disease. ( 27566884 )
2016
8
Brentuximab vedotin in the treatment of a patient with refractory Hodgkin disease and Proteus syndrome - a case report and discussion. ( 26273462 )
2015
9
Hodgkin disease (1973-2002): long-term survival and cure fractions. ( 25085435 )
2015
10
Brain metabolic changes in Hodgkin disease patients following diagnosis and during the disease course: An 18F-FDG PET/CT study. ( 25621038 )
2015
11
The Paris conference "La Radiothérapie de la Maladie de Hodgkin": a first step in the cure of Hodgkin disease. ( 25863747 )
2015
12
Dorothy Reed Mendenhall: expressions of a pioneer in Hodgkin disease. ( 25863749 )
2015
13
Hodgkin disease therapy induced second malignancy susceptibility 6q21 functional variants in roma and hungarian population samples. ( 24306881 )
2014
14
Retinal involvement in uveitis associated with hodgkin disease. ( 25372200 )
2014
15
Fertility preservation after caesarean delivery in a woman diagnosed with Morbus Hodgkin disease during pregnancy. ( 24221910 )
2014
16
Plasmacytoid dendritic cell and CD4 + T cell deficiencies in untreated Hodgkin disease: implications for susceptibility to opportunistic infections. ( 24547707 )
2014
17
Radiologic features of breast cancer after mantle radiation therapy for Hodgkin disease: a study of 230 cases. ( 24666474 )
2014
18
Primary extra nodal Hodgkin disease: Bone presentation. ( 24808935 )
2014
19
Hodgkin disease-an ever-evolving therapy. ( 25386345 )
2014
20
Bilateral Inflammatory Optic Neuropathy Related to Graft versus Host Disease Following Allogeneic Bone Marrow Transplantation for Hodgkin Disease. ( 27928304 )
2014
21
Systemic lupus erythematosus and Hodgkin disease. ( 24227520 )
2013
22
Hodgkin disease complicated by recurrent cardiac tamponade. ( 23596264 )
2013
23
Primary Hodgkin disease of the spine could mimic eosinophilic granuloma initially. ( 24034117 )
2013
24
Lymphocyte-predominant Hodgkin disease: a comprehensive overview. ( 21358294 )
2013
25
Cigarette smoking and risk of lymphoma in adults: a comprehensive meta-analysis on Hodgkin and non-Hodgkin disease. ( 22759975 )
2013
26
Early interim FDG PET/CT prediction of treatment response and prognosis in pediatric Hodgkin disease-added value of low-dose CT. ( 23151729 )
2013
27
Dynamic contrast-enhanced MRI improves accuracy for detecting focal splenic involvement in children and adolescents with Hodgkin disease. ( 23377561 )
2013
28
Coexistence of marginal zone cutaneous B-cell lymphoma and classic Hodgkin disease: does a biological relationship exist? ( 23551363 )
2013
29
Contribution of three-dimensional conformal intensity-modulated radiation therapy for women affected by bulky stage II supradiaphragmatic Hodgkin disease. ( 23638873 )
2013
30
Skin involvement with Hodgkin disease: a rare condition late in the course of Hodgkin lymphoma. ( 23686913 )
2013
31
Extraintestinal Hodgkin disease in a young man with Crohn disease treated with multiple immunosuppresive therapies. ( 23880629 )
2013
32
[Diagnostics, prognosis factors, and treatment of malignant lymphoproliferative disease, Hodgkin Disease]. ( 23035600 )
2012
33
Hodgkin disease relapse discovered at the time of liver transplant for acute liver failure. ( 21054714 )
2012
34
Rituximab as potential therapy for paraneoplastic cerebellar degeneration in pediatric Hodgkin disease. ( 22532986 )
2012
35
A 10-year experience with treatment of high and standard risk Hodgkin disease: six cycles of tailored BEACOPP, with interim scintigraphy, are effective and female fertility is preserved. ( 21956220 )
2012
36
PET/CT adapted therapy in Hodgkin disease: current state of the art and future directions. ( 22700011 )
2012
37
Frequency of surveillance scanning in pediatric Hodgkin disease can safely be reduced. ( 23001858 )
2012
38
Updated relevance of mammographic screening modalities in women previously treated with chest irradiation for Hodgkin disease. ( 23175541 )
2012
39
Hodgkin disease of the trachea. ( 23207461 )
2012
40
[Hodgkin disease and autoimmunity in children: 11 case reports]. ( 21397466 )
2011
41
Hemorrhagic Cystitis due to BK Reactivation in a Young Female Treated for Hodgkin-Disease. ( 22937308 )
2011
42
An uncommon association between parathyroid adenoma and Hodgkin disease. ( 21657156 )
2011
43
Impact of 18F-fluoro-2-deoxyglucose positron emission tomography on treatment strategy and radiotherapy planning for stage I-II Hodgkin disease: a prospective multicenter study. ( 20452732 )
2011
44
Hodgkin disease and the role of the immune system. ( 21381869 )
2011
45
Early-stage Hodgkin disease in a 24-year-old woman. ( 22082755 )
2011
46
Marathon of eponyms: 8 Hodgkin disease or lymphoma. ( 20374508 )
2010
47
[Combined therapy and radiotherapy in stage-II Hodgkin disease]. ( 21137247 )
2010
48
Nurses provide valuable proxy assessment of the health-related quality of life of children with Hodgkin disease. ( 20131350 )
2010
49
Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease. ( 20736843 )
2010
50
Late-onset cervicoscapular muscle atrophy and weakness after radiotherapy for Hodgkin disease: a case series. ( 20019226 )
2010

Variations for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Expression for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Search GEO for disease gene expression data for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance.

Pathways for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Pathways related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.86 BCL6 CR2 PTPRC
2
Show member pathways
11.5 BCL6 CR2 PTPRC
3 10.52 BCL6 CR2 PTPRC

GO Terms for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

Biological processes related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of B cell proliferation GO:0030890 9.16 BCL6 PTPRC
2 B cell proliferation GO:0042100 8.96 CR2 PTPRC
3 B cell differentiation GO:0030183 8.8 BCL6 CR2 PTPRC

Molecular functions related to Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 8.62 BCL6 ERF

Sources for Hodgkin's Lymphoma, Lymphocytic-Histiocytic Predominance

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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