Horner's Syndrome

Categories: Eye diseases, Fetal diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Horner's Syndrome

MalaCards integrated aliases for Horner's Syndrome:

Name: Horner's Syndrome 12 74 52 25 15
Horner Syndrome 12 25 43 71 32
Bernard-Horner Syndrome 52 25
Oculosympathetic Palsy 52 25
Cervical Sympathetic Paralysis 12
Cervical Sympathetic Dystrophy 71
Bernard Horner Syndrome 12
Von Passow Syndrome 25


External Ids:

Disease Ontology 12 DOID:11486
MeSH 43 D006732
NCIt 49 C28155
SNOMED-CT 67 192915005
ICD10 32 G90.2
UMLS 71 C0019937 C0391959

Summaries for Horner's Syndrome

Genetics Home Reference : 25 Horner syndrome is a disorder that affects the eye and surrounding tissues on one side of the face and results from paralysis of certain nerves. Horner syndrome can appear at any time of life; in about 5 percent of affected individuals, the disorder is present from birth (congenital). Horner syndrome is characterized by drooping of the upper eyelid (ptosis) on the affected side, a constricted pupil in the affected eye (miosis) resulting in unequal pupil size (anisocoria), and absent sweating (anhidrosis) on the affected side of the face. Sinking of the eye into its cavity (enophthalmos) and a bloodshot eye often occur in this disorder. In people with Horner syndrome that occurs before the age of 2, the colored part (iris) of the eyes may differ in color (iris heterochromia), with the iris of the affected eye being lighter in color than that of the unaffected eye. Individuals who develop Horner syndrome after age 2 do not generally have iris heterochromia. The abnormalities in the eye area related to Horner syndrome do not generally affect vision or health. However, the nerve damage that causes Horner syndrome may result from other health problems, some of which can be life-threatening.

MalaCards based summary : Horner's Syndrome, also known as horner syndrome, is related to cervical neuroblastoma and spindle cell sarcoma. An important gene associated with Horner's Syndrome is ADRA1A (Adrenoceptor Alpha 1A), and among its related pathways/superpathways are Mesenchymal Stem Cells and Lineage-specific Markers and Sympathetic Nerve Pathway (Neuroeffector Junction). The drugs Ketamine and Phenylephrine have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and testes, and related phenotype is homeostasis/metabolism.

NIH Rare Diseases : 52 Horner's syndrome is a rare condition characterized by miosis (constriction of the pupil), ptosis (drooping of the upper eyelid), and anhidrosis (absence of sweating of the face). It is caused by damage to the sympathetic nerves of the face. The underlying causes of Horner's syndrome vary greatly and may include a tumor , stroke, injury, or underlying disease affecting the areas surrounding the sympathetic nerves. In rare cases, Horner's syndrome is congenital (present from birth) and may be associated with a lack of pigmentation of the iris (colored part of the eye). Treatment of Horner's syndrome depends on the underlying cause.

Wikipedia : 74 Horner's syndrome, also known as oculosympathetic paresis, is a combination of symptoms that arises when... more...

Related Diseases for Horner's Syndrome

Diseases in the Horner's Syndrome family:

Horner Syndrome, Congenital

Diseases related to Horner's Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 408)
# Related Disease Score Top Affiliating Genes
1 cervical neuroblastoma 30.4 MYOG MYCN
2 spindle cell sarcoma 30.2 MYOG KRT7 DES
3 myofibroma 30.2 MYOG DES
4 dopamine beta-hydroxylase deficiency 29.9 TH ADRA2A
5 fibroma 29.9 NF1 KRT7 DES
6 malignant peripheral nerve sheath tumor 29.8 NF1 MYOG KRT7
7 embryonal rhabdomyosarcoma 29.7 MYOG MYOD1 MYCN DES
8 rhabdomyosarcoma 29.6 MYOG MYOD1 MYCN DES
9 ewing sarcoma 29.3 NF1 MYOG MYCN DES
10 heterochromia iridis 11.6
11 lateral medullary syndrome 11.6
12 klumpke paralysis 11.3
13 ptosis 10.8
14 pain agnosia 10.5
15 anhidrosis 10.5
16 breast rhabdomyosarcoma 10.5 MYOG MYOD1
17 enophthalmos 10.5
18 carotid artery dissection 10.5
19 undifferentiated embryonal sarcoma of the liver 10.5 MYOG MYOD1
20 pineal region teratoma 10.5 MYOG MYOD1
21 conventional leiomyosarcoma 10.5 MYOG MYOD1
22 prostate embryonal rhabdomyosarcoma 10.5 MYOG MYOD1
23 ocular hypotension 10.5 ADRA2A ADRA1A
24 skeletal muscle neoplasm 10.5 MYOG MYOD1
25 anisocoria 10.5
26 prostate rhabdomyosarcoma 10.5 MYOG MYOD1
27 adult fibrosarcoma 10.5 MYOG MYOD1
28 inflammatory leiomyosarcoma 10.5 MYOG DES
29 central nervous system mesenchymal non-meningothelial tumor 10.5 MYOG MYOD1
30 prostate sarcoma 10.5 MYOG MYOD1
31 neurilemmoma 10.5
32 cervical polyp 10.5 MYOG DES
33 malignant fibrous histiocytoma of bone 10.5 MYOD1 DES
34 medullomyoblastoma 10.5 MYOG DES
35 benign metastasizing leiomyoma 10.5 KRT7 DES
36 ectomesenchymoma 10.4 MYOG DES
37 liver sarcoma 10.4 MYOG KRT7
38 prostate stromal sarcoma 10.4 MYOG MYOD1
39 extraosseous ewing sarcoma 10.4 MYOG MYOD1
40 ovarian endodermal sinus tumor 10.4 KRT7 GPC3
41 parachordoma 10.4 KRT7 DES
42 prostatic adenoma 10.4 ADRA2A ADRA1A
43 ovarian primitive germ cell tumor 10.4 KRT7 GPC3
44 male reproductive organ benign neoplasm 10.4 ADRA2A ADRA1A
45 liver leiomyosarcoma 10.4 KRT7 GPC3
46 breast osteosarcoma 10.4 MYOG KRT7
47 goiter 10.4
48 uterus leiomyosarcoma 10.4 MYOG KRT7
49 sarcomatous intrahepatic cholangiocarcinoma 10.4 KRT7 GPC3
50 clear cell basal cell carcinoma 10.4 MYOG KRT7

Graphical network of the top 20 diseases related to Horner's Syndrome:

Diseases related to Horner's Syndrome

Symptoms & Phenotypes for Horner's Syndrome

MGI Mouse Phenotypes related to Horner's Syndrome:

# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.4 ADRA1A ADRA2A DES DFFA GPC3 GPR15

Drugs & Therapeutics for Horner's Syndrome

Drugs for Horner's Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
Phenylephrine Approved Phase 4 59-42-7 6041
Pseudoephedrine Approved Phase 4 90-82-4 7028
Ephedrine Approved Phase 4 299-42-3 9294
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
9 Pharmaceutical Solutions Phase 4
10 Analgesics Phase 4
11 Anesthetics, Intravenous Phase 4
12 Anesthetics, General Phase 4
13 Excitatory Amino Acid Antagonists Phase 4
14 Anesthetics, Dissociative Phase 4
15 Adrenergic alpha-Agonists Phase 4
16 Respiratory System Agents Phase 4
17 Adrenergic alpha-Antagonists Phase 4
18 Cardiotonic Agents Phase 4
19 Nasal Decongestants Phase 4
20 Adrenergic Agents Phase 4
21 Vasoconstrictor Agents Phase 4
22 Adrenergic Agonists Phase 4
23 Sympathomimetics Phase 4
24 Protective Agents Phase 4
25 Neurotransmitter Agents Phase 4
26 Mydriatics Phase 4
27 Anesthetics Phase 4
28 Anesthetics, Local Phase 4
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
Propofol Approved, Investigational, Vet_approved Phase 3 2078-54-8 4943
Mepivacaine Approved, Vet_approved Phase 3 96-88-8 4062
Epinephrine Approved, Vet_approved Phase 3 51-43-4 5816
Racepinephrine Approved Phase 3 329-65-7 838
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
Sevoflurane Approved, Vet_approved Phase 3 28523-86-6 5206
Ondansetron Approved Phase 3 99614-02-5 4595
Povidone-iodine Approved Phase 3 25655-41-8
Heparin Approved, Investigational Phase 3 9005-49-6 46507594 772
Enoxaparin Approved Phase 3 9005-49-6 772
Warfarin Approved Phase 3 81-81-2 6691 54678486
Clopidogrel Approved Phase 3 113665-84-2, 120202-66-6 60606
Dalteparin Approved Phase 3 9005-49-6
Tinzaparin Approved Phase 3 9041-08-1, 9005-49-6 25244225
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
Dipyridamole Approved Phase 3 58-32-2 3108
46 Anti-Inflammatory Agents Phase 3
47 Epinephryl borate Phase 3
48 Analgesics, Non-Narcotic Phase 3
49 Platelet Aggregation Inhibitors Phase 3
50 Fibrinolytic Agents Phase 3

Interventional clinical trials:

(show all 34)
# Name Status NCT ID Phase Drugs
1 Randomized Comparative Study Between Single-injection , Intra- Cluster -Injection and Double-injection Ultrasound-guided Supraclavicular Block of Brachial Plexus Unknown status NCT03188939 Phase 4
2 Combined Platelet Rich Plasma Intra-articular Shoulder Injection and Stellate Ganglion Block. A New Technique for Management of Chronic Post-mastectomy Shoulder Pain Syndrome Completed NCT03586154 Phase 4 ketamine and bupivacaine injection
3 Exploration of Pupil Dilation in Horner's Patients Taking Flomax Recruiting NCT03615508 Phase 4 10% phenylephrine
4 Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block Not yet recruiting NCT04209504 Phase 4 Ropivacaine;Bupivacaine
5 Does a Low Volume Ultrasound-Guided Technique Reduce Common Complications of Interscalene Brachial Plexus Block? Completed NCT00497354 Phase 3 Variation in volume of local anesthetic
6 A Comparison of Ultrasound-assisted Paravertebral Block and General Anesthesia for Outpatient Breast Cancer Surgery, a Prospective Randomized Trial Completed NCT00645138 Phase 3
7 Cervical Artery Dissection in Stroke Study Completed NCT00238667 Phase 3 Antiplatelet (Aspirin, Dipyridamole, clopidogrel);Anticoagulant (Unfractionated Heparin, LMW Heparin, Warfarin)
8 Three-level Injection Paravertebral Block Using Paravertebral Catheter Compared to General Anesthesia in Mastectomy Surgery Completed NCT02065947 Phase 1, Phase 2 fentanyl, propofol, atracurium;lidocaine , adrenaline, ketamine bolus, midazolam;sevoflurane and 50% oxygen in air
9 Efficacy Of Ultrasound Guided Stellate Ganglion Block To Relieve Vasospasm Following Clipping Of Cerebral Aneurysm Completed NCT02775318 Phase 1 Bupivacaine
10 Ocular Comorbidities of Alopecia Areata Unknown status NCT03155958
11 The Effect of Adding Phenol With Fluoroscopy Guided Radiofrequency Ablation of T2-T3 Versus Thoracoscopic Sympathectomy in Palmar Hyperhidrosis. Unknown status NCT03506828
12 Incidence of Transient Horner's Syndrome Following Thoracic Epidural Anesthesia for Mastectomy Completed NCT02130739 Ropivacaine;Propofol;Fentanyl
13 The Effects of Difference in Pupil Size Between Bilateral Eyes on Cardiac Sympathetic Nervous Activity Following Interscalene Brachial Plexus Block Completed NCT03514342 0.75% ropivacaine
14 Comparison Between Ultrasound-guided Supraclavicular and Interscalene Brachial Plexus Blocks in the Patients Undergoing Arthroscopic Shoulder Surgery Completed NCT01958801
15 Predicting the Occurence of Hypotensive Bradycardic Events in the Patients Undergoing Arthroscopic Shoulder Surgery in the Sitting Position Under Interscalene Brachial Plexus Block Completed NCT01926561
16 Is There a Difference Between Posterior Approach Ultrasound-guided Continuous Interscalene Block (Upper Trunk Block) and Stimulator Guided Continuous Cervical Paravertebral Block (C6 Root Block)? Completed NCT02769429
17 The Effect Of Initial Local Anesthetic Dose With Continuous Interscalene Analgesia On Postoperative Pain And Diaphragmatic Function In Arthroscopic Shoulder Surgery Patients: A Double-Blind, Randomized, Parallel Group, Dose-Ranging Study Completed NCT00672100 Ropivacaine;Ropivacaine;Ropivacaine
18 Analysis of the Status, Treatment and Outcomes of Rib Fractures Completed NCT02487264
19 Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair Position Under General Anesthesia Completed NCT01983618
20 Comparative Study of Bupivacaine Versus Bupivacaine-Dexmedetomidine in Ultrasound Guided Serratus Plane Block for Patients Undergoing Modified Radical Mastectomy Completed NCT03498092 Bupivacaine-Dexmedetomidine;Bupivacaine;General anesthesia
21 Assessment Effects of Somatosensorial and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke Completed NCT03477188
22 Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial Completed NCT01904266
23 Comparison of the Analgesic Duration of 0.5% Bupivacaine With 1:200,000 Epinephrine Versus 0.5% Ropivicaine Versus 1 % Ropivicaine for Low Volume Ultrasound-guided Interscalene Brachial Plexus Block Completed NCT02643563 Ropivacaine 0.5%;Ropivacaine 1%;Bupivacaine 0.5% + epinephrine 1:200,000
24 Assessment of Renal and Cervical Artery DysplasIA Completed NCT02884141
25 Automated Pupillometry for the Diagnosis of Horner's Syndrome in Acute Stroke Patients Due to Carotid Artery Dissection Recruiting NCT02978079
26 Role of Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease - Pilot Study Randomized Controlled Trial Recruiting NCT04239144
27 The Effectiveness of Pain Relieve of Ultrasound-guided Erector Spinae Plane Block Versus Serratus Anterior Plane Block With General Anesthesia in Modified Radical Mastectomy Patient (Randomized Double-Blinded Controlled Clinical Trial) Recruiting NCT03579524
28 Comparison of the Effects of Adding Dexamethasone at 0.25% Ropivacaine With 0.5% Ropivacaine Alone in the Supraclavicular Brachial Plexus Block Enrolling by invitation NCT03572686 Ropivacaine 0.5% 20mL;Ropivacaine 0.25% 20ml;Ropivacaine 0.25% 20ml + dexamethasone 8mg
29 Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracoscopic Surgery Not yet recruiting NCT04426097
30 Role of Pre Operative Vit D Administiration in Decrease Incidence of Post Thyroidectomy Hypocalcemia Not yet recruiting NCT04094493 Early Phase 1 vit D
31 "The Effect of Stellate Ganglion Block on Brain Haemodynamics and the Inflammatory Response in Moderate and Severe Brain Injury" Not yet recruiting NCT04208477
32 Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain Terminated NCT01954888
33 Does Left Cardiac Sympathectomy Stellate Ganglionectomy Confer an Added Benefit Over Optimal Medical Therapy in the Reduction of Therapy Delivered From an Implanted Cardioverter Defibrillator in Patients at High Risk of Sudden Cardiac Death Withdrawn NCT02113722
34 Standard Supraclavicular Block Versus Low-Volume Supraclavicular Block Plus Ulnar or Median Nerve Block for Hand Surgery in the Ulnar or Median Nerve Distribution Withdrawn NCT01625208

Search NIH Clinical Center for Horner's Syndrome

Cochrane evidence based reviews: horner syndrome

Genetic Tests for Horner's Syndrome

Anatomical Context for Horner's Syndrome

MalaCards organs/tissues related to Horner's Syndrome:

Eye, Thyroid, Testes, Breast, Brain, Lung, Spinal Cord

Publications for Horner's Syndrome

Articles related to Horner's Syndrome:

(show top 50) (show all 2468)
# Title Authors PMID Year
Ultrasonographic needle tip tracking for in-plane infraclavicular brachialis plexus blocks: a randomized controlled volunteer study. 61
32540878 2020
Trapdoor anterior thoracotomy for cervicothoracic and apical thoracic neuroblastoma in children. 61
32514720 2020
[A case of bilateral medial medullary and left tegmentum of pontine infarction in whom DSA-MR fusion imaging identified infarct-relevant arteries]. 61
32435047 2020
The risk of a serious etiology in pediatric Horner syndrome: indications for a workup and which investigations to perform. 61
32522708 2020
Horner Syndrome Caused by Internal Jugular Vein Catheterization. 61
31350153 2020
Horner Syndrome induced by toxoplasmosis infection in a patient with AIDS and disseminated herpes simplex virus. 61
32346650 2020
Cordotomy for Intractable Cancer Pain: A Narrative Review. 61
32517394 2020
Transposition of the left vertebral artery during endovascular stent-graft repair of the aortic arch. 61
31301891 2020
Ultrasound Image Guided Lateral Cervical Approach to Stellate Ganglion Block for Cervical Headache. 61
32522602 2020
Incidence and Prognostic Role of the Ocular Manifestations of Neuroblastoma in Children. 61
32006485 2020
Robotic Staged Bilateral Selective Postganglionic Sympathectomy for Upper-Extremity Hyperhidrosis. 61
32250442 2020
Horner syndrome and malignancy. 61
32416053 2020
A novel case and review of paediatric Horner syndrome. 61
32415189 2020
Investigation of Pupillary Changes After Carotid Endarterectomy and Carotid Stent Placement Using Automated Pupillometry. 61
32107154 2020
Vertebrobasilar ischemia (VBI) related neuro-ophthalmic syndromes after routine activities involving hyperextension or rotation of the neck (hairdresser syndrome). 61
31570813 2020
Retropharyngeal Abscess. Clinical Review of Twenty-five Years. 61
32487430 2020
Atypical Horner's syndrome: frequency, features and aetiology in a paediatric population. 61
32424330 2020
Clinical signs, MRI findings and outcome in dogs with peripheral vestibular disease: a retrospective study. 61
32450859 2020
Anesthetic and Analgesic Efficient of Regional Nerve Blockade in Otoplasty. 61
32371690 2020
Surgical Treatment of Vertebral Artery Stenosis: An Overlooked Surgery with Low Morbidity. 61
32439529 2020
Effectiveness, Safety, and Predictive Potential in Ultrasound-Guided Stellate Ganglion Blockades for the Treatment of Sympathetically Maintained Pain. 61
32255250 2020
Horner Syndrome Due To Internal Carotid Artery Dissection With Normal Vascular Imaging: A Radiological Conundrum. 61
32355049 2020
Cardiac sympathetic denervation in patients with nonischemic cardiomyopathy and refractory ventricular arrhythmias: a single-center experience. 61
32328735 2020
Isolated pituitary fossa metastasis from a primary tonsillar squamous cell carcinoma: case report. 61
32234087 2020
[Do we inspecting the patient face who has shoulder pain?] 61
32297960 2020
Cervical sympathetic schwannoma: a forgotten differential for Horner's syndrome. 61
31230401 2020
A Complete Triad: Horner's Syndrome in Tuberculous Meningitis. 61
32317170 2020
Complications of anterior cervical spine surgery: a systematic review of the literature. 61
32309668 2020
Horner syndrome secondary to cephalic paravertebral migration of local anaesthetic. 61
29248209 2020
Superficial Stab Wound to Zone I of the Neck Resulting in Thyrocervical Trunk Pseudoaneurysm Presented as Recurrent Hemothorax and Successfully Managed by Coil Embolization. 61
32146480 2020
Emergent Phenol Injection of Bilateral Stellate Ganglion for Management of Refractory Malignant Ventricular Arrhythmias. 61
32188839 2020
A retrospective evaluation of systemic and/or topical pilocarpine treatment for canine neurogenic dry eye: 11 cases. 61
31872935 2020
Diagnostic Values of Clinical and Magnetic Resonance Findings in Presumptive Trigeminal Neuropathy: 49 Dogs. 61
31961212 2020
Correction: Paediatric Horner's syndrome: is investigation for underlying malignancy always required? 61
31907176 2020
Horner's syndrome and apraclonidine eye drops. 61
32184344 2020
The relevance of anhidrosis in Horner syndrome: Analysis of an image. 61
29277520 2020
Treatment of Ptosis Using Brimonidine Tartrate for Anterior Laminectomy-Induced Horner Syndrome. 61
31609842 2020
A Rare Catheter Complication in a Patient With Neuroblastoma: Horner's Syndrome. 61
31876676 2020
Neuromyelitis Optica as an Initial Presentation of Systemic Lupus Erythematosus in a Young Male. 61
32169145 2020
Transoral robotic surgery for the parapharyngeal space: expanding the transoral corridor. 61
30762172 2020
Internal carotid artery occlusion may affect long-term quality of life in patients with high-flow carotid cavernous fistulas. 61
31333051 2020
Identical Horner Syndrome in Homozygotic Twins Caused by Non-Traumatic Internal Carotid Artery Dissection. 61
32076445 2020
Internal Carotid Artery Dissection Presenting as Partial Horner's Syndrome and Vertigo. 61
32060548 2020
Horner Syndrome from a Pediatric Otolaryngology Perspective. 61
31561707 2020
Delayed Horner Syndrome and Accessory Nerve Weakness After Papillary Thyroid Carcinoma Surgery. 61
32075435 2020
Horner syndrome secondary to Hodgkin lymphoma. 61
32094269 2020
Horner's Syndrome with Unilateral Brachial Plexus Blockade Mimicking Cerebrovascular Accident Following Lumbar Combined Spinal Epidural Analgesia for Labor. 61
31504771 2020
Neuro-Ophthalmic Injuries With Systemic Neurologic Injury or Traumatic Brain Injury in Operation Iraqi Freedom and Operation Enduring Freedom. 61
32108667 2020
Horner Syndrome After Anterior Cervical Discectomy and Fusion: Case Series and Systematic Review. 61
31465851 2020
Incidental intrathorcic schwannoma post upper respiratory tract infection associated with Horner's syndrome: A case report. 61
32577367 2020

Variations for Horner's Syndrome

Expression for Horner's Syndrome

Search GEO for disease gene expression data for Horner's Syndrome.

Pathways for Horner's Syndrome

Pathways related to Horner's Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.78 MYOG MYOD1 DES
2 10.52 ADRA2A ADRA1A
Show member pathways
10.32 TH ADRA2A

GO Terms for Horner's Syndrome

Biological processes related to Horner's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of vasoconstriction GO:0019229 9.48 ADRA2A ADRA1A
2 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.46 ADRA2A ADRA1A
3 positive regulation of myoblast differentiation GO:0045663 9.43 MYOG MYOD1
4 positive regulation of myoblast fusion GO:1901741 9.4 MYOG MYOD1
5 myoblast differentiation GO:0045445 9.37 MYOG MYOD1
6 myotube differentiation GO:0014902 9.32 MYOG MYOD1
7 adrenergic receptor signaling pathway GO:0071875 9.26 ADRA2A ADRA1A
8 positive regulation of skeletal muscle fiber development GO:0048743 9.16 MYOG MYOD1
9 muscle cell fate commitment GO:0042693 8.96 MYOG MYOD1
10 skeletal muscle tissue development GO:0007519 8.8 NF1 MYOG MYOD1

Molecular functions related to Horner's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adrenergic receptor activity GO:0004935 8.62 ADRA2A ADRA1A

Sources for Horner's Syndrome

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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