MCID: HTL001
MIFTS: 36

Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

MalaCards integrated aliases for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

Name: Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis 53
Human T-Cell Leukemia Virus Type 1 Associated Myelopathy/tropical Spastic Paraparesis 53
Tropical Spastic Paraparesis 72
Ham/tsp 53

Classifications:



External Ids:

UMLS 72 C0030481

Summaries for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

NIH Rare Diseases : 53 HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the nervous system that affects less than 2% of people with HTLV-1 infection. Signs and symptoms vary but may include slowly progressive weakness and spasticity of one or both legs, exaggerated reflexes, muscle contractions in the ankle, and lower back pain. Other features may include urinary incontinence and minor sensory changes, especially burning or prickling sensations and loss of vibration sense. The reason some people with HTLV-1 infection develop HAM/TSTP is not well understood. Treatment generally aims to control the specific symptoms, as there is no standard treatment available. Interferon alpha may be beneficial over short periods, and some aspects of the disease may be improved with interferon beta. Other medications may include immune globulin, oral corticosteroids, and muscle relaxers such as baclofen or tizanidine.

MalaCards based summary : Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis, also known as human t-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis, is related to tropical spastic paraparesis and human immunodeficiency virus type 1. An important gene associated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis is HLA-A (Major Histocompatibility Complex, Class I, A), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. The drugs Pentoxifylline and Zidovudine have been mentioned in the context of this disorder. Affiliated tissues include t cells, spinal cord and brain, and related phenotypes are hematopoietic system and immune system

Related Diseases for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Diseases related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 85, show less)
# Related Disease Score Top Affiliating Genes
1 tropical spastic paraparesis 32.2 IFNL3 FOXP3 CXCR3
2 human immunodeficiency virus type 1 29.3 HLA-A CX3CR1 CD274
3 myelopathy, htlv-1-associated 12.2
4 human t-cell leukemia virus type 1 12.2
5 retrovirus-associated myelopathy 11.8
6 spastic paraparesis 11.1
7 t-cell leukemia 10.8
8 leukemia, t-cell, chronic 10.8
9 adult t-cell leukemia 10.8
10 dermatitis 10.6
11 infective dermatitis associated with htlv-1 10.6
12 t-cell adult acute lymphocytic leukemia 10.5
13 spasticity 10.5
14 myelitis 10.5
15 myositis 10.3
16 3-methylglutaconic aciduria, type iii 10.3
17 sexual disorder 10.3
18 lymphoma 10.3
19 polyneuropathy 10.3
20 optic nerve disease 10.3
21 cerebellar disease 10.3
22 central nervous system disease 10.3
23 skin disease 10.3
24 syphilis 10.3
25 myopathy 10.3
26 peripheral nervous system disease 10.3
27 axonal neuropathy 10.3
28 nervous system disease 10.3
29 neuropathy 10.3
30 48,xyyy 10.3
31 autonomic dysfunction 10.3
32 tremor 10.3
33 candidiasis, familial, 1 10.3
34 meningoencephalitis 10.3
35 neurogenic bladder 10.3
36 detrusor sphincter dyssynergia 10.3
37 uveitis 10.3
38 thyroiditis 10.3
39 amyotrophic lateral sclerosis 1 10.2
40 autoimmune disease 10.2
41 multiple sclerosis 10.2
42 kaposi sarcoma 10.2
43 osteoporosis 10.2
44 bone mineral density quantitative trait locus 8 10.2
45 pseudopseudohypoparathyroidism 10.2
46 bone mineral density quantitative trait locus 15 10.2
47 secondary progressive multiple sclerosis 10.2
48 primary progressive multiple sclerosis 10.2
49 strongyloidiasis 10.2
50 autonomic neuropathy 10.2
51 goiter 10.2
52 diarrhea 10.2
53 beriberi 10.2
54 oral candidiasis 10.2
55 candidiasis 10.2
56 lateral sclerosis 10.2
57 relapsing-remitting multiple sclerosis 10.2
58 wernicke encephalopathy 10.2
59 sensory peripheral neuropathy 10.2
60 spinal cord disease 10.2
61 demyelinating disease 10.2
62 vaccinia 10.2
63 acquired immunodeficiency syndrome 10.2
64 viral encephalitis 10.2
65 encephalitis 10.2
66 47,xyy 10.2
67 aids dementia complex 10.2
68 cytokine deficiency 10.2
69 depression 10.2
70 back pain 10.2
71 chronic pain 10.2
72 hypertonia 10.2
73 rare neurodegenerative disease 10.2
74 inflammatory myopathy with abundant macrophages 10.2
75 caplan's syndrome 10.1 HLA-A FOXP3
76 thymic dysplasia 10.0 HLA-A FOXP3
77 anal canal adenocarcinoma 10.0 FOXP3 CD274
78 vulvar melanoma 10.0 FOXP3 CD274
79 chromoblastomycosis 9.8 HLA-A CXCR3
80 stevens-johnson syndrome/toxic epidermal necrolysis 9.7 HLA-A CXCR3
81 alk-negative anaplastic large cell lymphoma 9.7 CXCR3 CD274
82 lichen disease 9.6 FOXP3 CXCR3
83 cryoglobulinemia 9.5 IFNL3 CXCR3
84 autoimmune disease of central nervous system 9.4 FOXP3 CXCR3
85 malaria 8.8 HLA-A FOXP3 CXCR3

Graphical network of the top 20 diseases related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:



Diseases related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Symptoms & Phenotypes for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

MGI Mouse Phenotypes related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

46 (showing 2, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 CD274 CX3CR1 CXCR3 FOXP3 IFNL3
2 immune system MP:0005387 9.02 CD274 CX3CR1 CXCR3 FOXP3 IFNL3

Drugs & Therapeutics for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Drugs for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 46, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
2
Zidovudine Approved Phase 2, Phase 3 30516-87-1 35370
3
Lamivudine Approved, Investigational Phase 2, Phase 3 134678-17-4 60825
4
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3 22916-47-8 4189
5 Anti-Infective Agents Phase 2, Phase 3
6 Anti-HIV Agents Phase 2, Phase 3
7 Anti-Retroviral Agents Phase 2, Phase 3
8 Antiviral Agents Phase 2, Phase 3
9 Free Radical Scavengers Phase 3
10 Antioxidants Phase 3
11 Phosphodiesterase Inhibitors Phase 3
12 Protective Agents Phase 3
13 Radiation-Protective Agents Phase 3
14 Platelet Aggregation Inhibitors Phase 3
15 Vasodilator Agents Phase 3
16 Dermatologic Agents Phase 2, Phase 3
17 Antirheumatic Agents Phase 2, Phase 3
18 Immunologic Factors Phase 2, Phase 3
19 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3
20 Reverse Transcriptase Inhibitors Phase 2, Phase 3
21 Antimetabolites Phase 2, Phase 3
22 Antifungal Agents Phase 2, Phase 3
23 Cyclosporins Phase 2, Phase 3
24 Immunosuppressive Agents Phase 2, Phase 3
25 Calcineurin Inhibitors Phase 2, Phase 3
26
Interferon beta-1a Approved, Investigational Phase 2 145258-61-3 6438354
27
Infliximab Approved Phase 2 170277-31-3
28 Adjuvants, Immunologic Phase 2
29 Interferon-beta Phase 2
30 interferons Phase 2
31 Janus Kinase Inhibitors Phase 2
32 Gastrointestinal Agents Phase 2
33 Antibodies Phase 1
34 Antibodies, Monoclonal Phase 1
35 Immunoglobulins Phase 1
36
Valproic acid Approved, Investigational 99-66-1 3121
37 Raltegravir Potassium Early Phase 1
38 Integrase Inhibitors Early Phase 1
39 HIV Integrase Inhibitors Early Phase 1
40 Neurotransmitter Agents
41 Central Nervous System Depressants
42 Tranquilizing Agents
43 Psychotropic Drugs
44 GABA Agents
45 Anticonvulsants
46 Antimanic Agents

Interventional clinical trials:

(showing 19, show less)
# Name Status NCT ID Phase Drugs
1 Open-Label, Exploratory Study of the Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Unknown status NCT01343355 Phase 2, Phase 3 Tamibarotene
2 Effectiveness of Pentoxifylline in Attenuating Neurological Disease Associated With HTLV-1 and Negative Modulator of Pathological Immune Response. Completed NCT01472263 Phase 3 Pentoxifylline;Placebo
3 Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial Completed NCT00272480 Phase 2, Phase 3 Zidovudine/lamivudine;Placebos
4 The HAM Ciclosporin Study : an Observational Trial of Therapy in Early or Progressing HAM/TSP Completed NCT00773292 Phase 2, Phase 3 ciclosporin
5 Combined Virological and Immunological Evaluation of Treatment of Patients With Early HTLV-1-Associated Myelopathy With Recombinant Human Interferon Beta-1a Completed NCT00001785 Phase 2 Recombinant human interferon beta-1a
6 Phase II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients With Smoldering and Chronic Adult T-cell Leukemia (ATL) Recruiting NCT01712659 Phase 2 Ruxolitinib;ruxolitinib
7 An Open, Non-randomised Pilot Study of Anti-TNF-alpha Therapy in Early or Progressing HAM/TSP Terminated NCT00823641 Phase 2 Infliximab
8 Phase I Study of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Using the Humanized MiK-Beta-1 Monoclonal Antibody Directed Toward the IL-2L-15R-Beta; Subunit (CD122) That Blocks IL-15 Action Completed NCT00076843 Phase 1 Hu MiK-Beta-1
9 MRI Investigation Of The CNS In HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Completed NCT00034723
10 Effects of Physiotherapy in the Treatment of Neurogenic Bladder in Patients Infected With Human T-Lymphotropic Virus 1 Completed NCT01651819
11 Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP) Completed NCT01867320 Early Phase 1 Raltegravir
12 A Study of Familial and Genetic Aspects of Adult T-Cell Leukemia/Lymphoma, Tropical Spastic Paraparesis and Infective Dermatitis in Jamaica Completed NCT00340821
13 NIB Repository Protocol Completed NCT01581567
14 Effect of Raltegravir in Patients With Myelopathy/Tropical Spastic Paraparesis Associated With Infection by Human T-Lymphotropic Virus 1 (HTLV-1). Pilot Study Completed NCT02655471 Early Phase 1 "Raltegravir" and "Zidovudine"
15 Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1 Completed NCT01754311
16 Retrovirus Epidemiology Donor Study I (REDS I) Completed NCT00005278
17 Immuno-Virological Evaluation of Human T Cell Lymphotropic Virus Infection and Associated Neurological Diseases Recruiting NCT00001778
18 Electromiography Study in the Respiratory Muscle Training in Human Lymphotropic Virus Type 1 Recruiting NCT03829709
19 Open Label Study of the Clinical and Laboratory Effects of Valproic Acid In HAM/TSP Terminated NCT00519181 Valproic Acid

Search NIH Clinical Center for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Genetic Tests for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Anatomical Context for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

MalaCards organs/tissues related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

41
T Cells, Spinal Cord, Brain, Monocytes, B Cells, Testes, Bone

Publications for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

Articles related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

(showing 1497, show less)
# Title Authors PMID Year
1
Curcumin increased the expression of c-FLIP in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. 38
31074052 2019
2
Conflicting effects of poly(ADP-ribose) polymerase inhibitor on cell-mediated and virion-mediated HTLV-1 infection. 38
31299194 2019
3
Comparative virology of HTLV-1 and HTLV-2. 38
31391116 2019
4
Human T-Cell Lymphotropic Virus Type 1 and associated diseases in Latin America. 38
31183938 2019
5
Hodgkin-like adult T-cell leukemia/lymphoma that developed during the follow-up of HTLV-1 associated myelopathy/tropical spastic paraparesis. 38
31391405 2019
6
Balance Impairments in Patients with Human T-Cell Lymphotropic Virus Type 1 Infection. 38
31391511 2019
7
Clinical trial of a humanized anti-IL-2/IL-15 receptor β chain in HAM/TSP. 38
31402625 2019
8
Current approaches for detection of human T-lymphotropic virus Type 1: A systematic review. 38
30633358 2019
9
Pentosan Polysulfate Demonstrates Anti-human T-Cell Leukemia Virus Type 1 Activities In Vitro and In Vivo. 38
31167921 2019
10
Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type. 38
31340370 2019
11
Repurposing multiple sclerosis drugs: a review of studies in neurological and psychiatric conditions. 38
31100209 2019
12
Memory impairment: an intermediate clinical syndrome symptom in HTLV-1-infected patients? 38
31314846 2019
13
Phenotypic and functional changes in gamma delta T lymphocytes from HTLV-1 carriers. 38
31287591 2019
14
Prevalence of human T-cell lymphotropic virus and the socio-demographic and risk factors associated with the infection among post-natal clinics women in Zaria, Nigeria. 38
31339431 2019
15
Essential Role of HTLV-1 orf-I in Lethal Proliferation of CD4+ Cells in Humanized Mice. 38
31315992 2019
16
HTLV-1-infected asymptomatic carriers compared to HAM/TSP patients over-express the apoptosis- and cytotoxicity-related molecules. 38
31317252 2019
17
Delimitation of the upstream region of NFKBIA gene associated with HTLV-1-associated myelopathy/tropical spastic paraparesis using candidate Tag-SNPs in Peruvian HTLV-1 infected individuals. 38
31226330 2019
18
Human T-cell lymphotropic virus 1/2 and human immunodeficiency virus antibodies identification among transactional sex workers and drug users in the Dominican Republic. 38
30892643 2019
19
Functional capacity of natural killer cells in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. 38
31101076 2019
20
Thioredoxin reductase gene expression and activity among human T-cell lymphotropic virus type 1-infected patients. 38
30489643 2019
21
Pain and Quality of Life in Human T-cell Lymphotropic Virus Type 1-Associated Myelopathy or Tropical Spastic Paraparesis After Home-Based Exercise Protocol: A Randomized Clinical Trial. 38
31038621 2019
22
Efficacy of mirabegron for overactive bladder with human T cell lymphotropic virus-1 associated myelopathy. 38
29473309 2019
23
Infective dermatitis: A purely cutaneous manifestation of HTLV-1 infection. 38
31010607 2019
24
Seroprevalence of HTLV-1/2 Among Voluntary Blood Donors in Vietnam. 38
30565470 2019
25
Role of Receptors for Advanced Glycation End Products and High-Mobility Group Box 1 in the Outcome of Human T Cell Lymphotropic Type 1 Infection. 38
30585773 2019
26
Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load. 38
31059675 2019
27
Incomplete myelopathy and human T cell lymphotropic virus type-1 (HTLV-1). 38
30291566 2019
28
Robust, atlas-free, automatic segmentation of brain MRI in health and disease. 38
30828660 2019
29
Association Between HTLV-1 Genotypes and Risk of HAM/TSP. 38
31156605 2019
30
Molecular detection of human T-lymphotropic virus type 1 infection among oncology patients in Germany: A retrospective view. 38
31136642 2019
31
The Role of CXCR3 in Neurological Diseases. 38
29119926 2019
32
Molecular targeting for treatment of human T-lymphotropic virus type 1 infection. 38
30551530 2019
33
Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
31105674 2019
34
Infective dermatitis associated with HTLV-1 infection in a girl from Trinidad: Case report and review of literature. 38
30338553 2019
35
HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients. 38
31080441 2019
36
The Role of NK Cells in the Control of Viral Infection in HTLV-1 Carriers. 38
30944834 2019
37
TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins. 38
31244811 2019
38
Human T-Lymphotropic Virus-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Associated With Sexual Dysfunction in Infected Women of Reproductive Age. 38
30181035 2018
39
A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions. 38
29373673 2018
40
Local and systemic production of proinflammatory chemokines in the pathogenesis of HAM/TSP. 38
30473006 2018
41
HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions. 38
30577817 2018
42
Cytokine Networks Dysregulation during HTLV-1 Infection and Associated Diseases. 38
30563084 2018
43
Isolated Neurogenic Bladder Associated With Human T-Lymphotropic Virus Type 1 Infection in a Renal Transplant Patient From Central Australia: A Case Report. 38
30577291 2018
44
Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil. 38
30466392 2018
45
Unconventional secretion of viral proteins. 38
29571970 2018
46
Non-Structural Proteins from Human T-cell Leukemia Virus Type 1 in Cellular Membranes-Mechanisms for Viral Survivability and Proliferation. 38
30413005 2018
47
TAX-mRNA-Carrying Exosomes from Human T Cell Lymphotropic Virus Type 1-Infected Cells Can Induce Interferon-Gamma Production In Vitro. 38
30229663 2018
48
Different roles of CXCR1 and CXCR2 in HTLV-1 carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. 38
30341468 2018
49
Early Juvenile Human T-cell Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: Study of 25 Patients. 38
29912303 2018
50
HTLV-1: A real pathogen or a runaway guest of a diseased cell? 38
30207322 2018
51
Protein Profile of Blood Monocytes is Altered in HTLV-1 Infected Patients: Implications for HAM/TSP Disease. 38
30254298 2018
52
HTLV-1 proviral load in cerebrospinal fluid may not be a good marker to differentiate asymptomatic carriers with high proviral load in blood from HAM/TSP patients. 38
29589290 2018
53
Viral antigens detectable in CSF exosomes from patients with retrovirus associated neurologic disease: functional role of exosomes. 38
30146667 2018
54
In vivo and in vitro immunogenicity of novel MHC class I presented epitopes to confer protective immunity against chronic HTLV-1 infection. 38
30005946 2018
55
The role of human T-lymphotropic virus (HTLV) in cardiovascular diseases: A review of literature. 38
30627195 2018
56
Human T-lymphotropic virus 1 associated with adult T-cell leukemia/lymphoma. 38
30138509 2018
57
Parkinsonism in a Patient with Human T-lymphotropic Virus 1 Myelopathy. 38
30202671 2018
58
The impact of urinary incontinence on the quality of life and on the sexuality of patients with HAM/TSP. 38
30145198 2018
59
HTLV-1/2 prevalence in two Amazonian communities. 38
30050680 2018
60
Sensory neuronopathy heralding human T cell lymphotropic virus type I myelopathy. 38
29318453 2018
61
Human T-lymphotropic virus 1 (HTLV-1) pathogenesis: A systems virology study. 38
29227540 2018
62
Role of Integrin Signaling Activation on the Development of Human T Cell Leukemia Virus-1 (HTLV-1)-Associated Myelopathy/Tropical Spastic Paraparesis: Its Relationship to HTLV-1-Infected CD4+ T Cell Transmigrating Activity into the Tissues. 38
29400072 2018
63
Early Onset of HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) and Adult T-cell Leukemia/Lymphoma (ATL): Systematic Search and Review. 38
28582585 2018
64
Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases. 38
29709026 2018
65
Balance, functional mobility, and fall occurrence in patients with human T-cell lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis: a cross-sectional study. 38
29768548 2018
66
Temporal trends in Human T-Lymphotropic virus 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis (HAM/TSP) incidence in Martinique over 25 years (1986-2010). 38
29554087 2018
67
Multiple spotty lesions of the spinal cord in a Chinese patient with human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis. 38
29292042 2018
68
Systemic diseases in patients with HTLV-1-associated uveitis. 38
28689168 2018
69
[SHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015]. 38
29668132 2018
70
In vitro basal T-cell proliferation among asymptomatic Human T cell Leukemia Virus type 1 patients co-infected with hepatitis C and/or Human Immunodeficiency Virus type 1. 38
29499169 2018
71
HTLV-1 intrafamilial transmission among Japanese immigrants in Brazil. 38
28876483 2018
72
Infectious diseases causing autonomic dysfunction. 38
28730326 2018
73
Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy. 38
29414279 2018
74
HTLV-1-Mediated Epigenetic Pathway to Adult T-Cell Leukemia-Lymphoma. 38
30087673 2018
75
Prosultiamine for treatment of lower urinary tract dysfunction accompanied by human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis. 38
28965354 2018
76
Interferon Lambda Family along with HTLV-1 Proviral Load, Tax, and HBZ Implicated in the Pathogenesis of Myelopathy/Tropical Spastic Paraparesis. 38
29990995 2018
77
Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity. 38
30090093 2018
78
Rate of positive autoimmune markers in Human T lymphotropic virus type 1 carriers: a case-control study from Iran. 38
28261958 2018
79
How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy. 38
29593659 2018
80
HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role. 38
29515558 2018
81
Low genetic diversity of the Human T-cell Lymphotropic Virus (HTLV-1) in an endemic area of the Brazilian Amazon basin. 38
29558516 2018
82
The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
29202792 2017
83
Retinal Nerve Fiber Layer Thickness in Human T-cell Lymphotropic Virus Type 1 Patients. 38
28985098 2017
84
HTLV-1-infected thymic epithelial cells convey the virus to CD4+ T lymphocytes. 38
28888743 2017
85
Mediators Go Together: High Production of CXCL9, CXCL10, IFN-γ, and TNF-α in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
28648091 2017
86
[Tropical spastic paraparesis - anesthetic approach]. 38
26626318 2017
87
Association of Tuberculosis Status with Neurologic Disease and Immune Response in HTLV-1 Infection. 38
28540757 2017
88
Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. 38
29186194 2017
89
Imaging spinal cord atrophy in progressive myelopathies: HTLV-I-associated neurological disease (HAM/TSP) and multiple sclerosis (MS). 38
29024167 2017
90
Central motor pathways in tropical spastic paraparesis: a combined transcranial magnetic stimulation and diffusion tensor imaging study. 38
30944510 2017
91
Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study. 38
28536850 2017
92
Spinal cord anteroposterior atrophy in HAM/TSP: Magnetic resonance imaging and neuropathological analyses. 38
28991665 2017
93
Downregulation of histone methyltransferase EHMT2 in CD4+ T-cells may protect HTLV-1-infected individuals against HAM/TSP development. 38
28608127 2017
94
Risk Factors for Erectile Dysfunction in Men With HTLV-1. 38
28827086 2017
95
HTLV infection in HCV-antibody positive patients in Spain. 38
28269998 2017
96
Human T-cell leukaemia virus type 1: parasitism and pathogenesis. 38
28893939 2017
97
HTLV-1 infection in Reunion. 38
28651832 2017
98
HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/- (RAG1-Hu) and BLT Mice. 38
28374110 2017
99
IL-10-mediated signals act as a switch for lymphoproliferation in Human T-cell leukemia virus type-1 infection by activating the STAT3 and IRF4 pathways. 38
28910419 2017
100
Evaluation of T Regulatory Lymphocytes Transcription Factors in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Patients. 38
28101786 2017
101
Indigenous tropical spastic paraparesis in Madrid (Spain). Experience on screening of human T-lymphotropic virus. 38
26282070 2017
102
Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line. 38
28615198 2017
103
The Duffy null genotype is associated with a lower level of CCL2, leukocytes and neutrophil count but not with the clinical outcome of HTLV-1 infection. 38
28771137 2017
104
Altered expression of CXCR3 and CCR6 and their ligands in HTLV-1 carriers and HAM/TSP patients. 38
28206670 2017
105
Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: The First Case Report in Southeast Asia. 38
28343405 2017
106
Case for diagnosis. Infective dermatitis associated with HTLV-1: differential diagnosis of atopic dermatitis. 38
28954118 2017
107
Prevalence of plasma autoantibody against cancer testis antigen NY-ESO-1 in HTLV-1 infected individuals with different clinical status. 38
28716148 2017
108
Human T-lymphotropic virus type 1 infection and disease in Spain. 38
28700391 2017
109
Role of IL-21 in HTLV-1 infections with emphasis on HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
28378248 2017
110
Evaluation of HTLV-1 HBZ and proviral load, together with host IFN λ3, in pathogenesis of HAM/TSP. 38
27787900 2017
111
IL17A Polymorphism Is Not Associated with Human T-Lymphotropic Virus 1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
28410448 2017
112
Human T Cell Leukemia Virus Type 1 and Eye Diseases. 38
28263674 2017
113
Cardiovascular risk profile in patients with myelopathy associated with HTLV-1. 38
28282508 2017
114
Flow cytometric-based protocols for assessing anti-MT-2 IgG1 reactivity: High-dimensional data handling to define predictors for clinical follow-up of Human T-cell Leukemia virus type-1 infection. 38
28212879 2017
115
Hepatitis C virus and human T-cell lymphotropic virus type 1 co-infection: impact on liver disease, virological markers, and neurological outcomes. 38
28185943 2017
116
The FAS-670 AA genotype is associated with high proviral load in peruvian HAM/TSP patients. 38
27603042 2017
117
Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
28420387 2017
118
Clinical and laboratory features of HTLV-I asymptomatic carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis from the Brazilian Amazon. 38
28380116 2017
119
Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells. 38
28426803 2017
120
Autoantibodies to heterogeneous nuclear ribonuclear protein A1 (hnRNPA1) cause altered 'ribostasis' and neurodegeneration; the legacy of HAM/TSP as a model of progressive multiple sclerosis. 38
27449854 2017
121
HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP. 38
27542993 2017
122
Dynamic acquisition of HTLV-1 tax protein by mononuclear phagocytes: Role in neurologic disease. 38
27769524 2017
123
Schistosoma antigens downregulate CXCL9 production by PBMC of HTLV-1-infected individuals. 38
28040482 2017
124
Treatment of rheumatoid arthritis with biologics may exacerbate HTLV-1-associated conditions: A case report. 38
28178142 2017
125
Retrospective clinic and urodynamic study in the neurogenic bladder dysfunction caused by human T cell lymphotrophic virus type 1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
26756420 2017
126
Prevalence and risk factors for Human T-Lymphotropic Virus Type 1 (HTLV-1) among maintenance hemodialysis patients. 38
28202003 2017
127
Long-term follow-up of HTLV-1 proviral load in asymptomatic carriers and in incident cases of HAM/TSP: what is its relevance as a prognostic marker for neurologic disease? 38
27678093 2017
128
Evaluation of Line Immunoassay to Detect HTLV-1 Infection in an Endemic Area, Southwestern Japan; Comparison with Polymerase Chain Reaction and Western Blot. 38
28182361 2017
129
Modulatory effects of curcumin on apoptosis and cytotoxicity-related molecules in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. 38
27894665 2017
130
The effect of HTLV-1 virulence factors (HBZ, Tax, proviral load), HLA class I and plasma neopterin on manifestation of HTLV-1 associated myelopathy tropical spastic paraparesis. 38
27845163 2017
131
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). 38
28095504 2017
132
CT Chest and pulmonary functional changes in patients with HTLV-associated myelopathy in the Eastern Brazilian Amazon. 38
29095831 2017
133
Expression of HTLV-1 Genes in T-Cells Using RNA Electroporation. 38
28357669 2017
134
Role of the HTLV-1 viral factors in the induction of apoptosis. 38
27887847 2017
135
Reducing the global burden of HTLV-1 infection: An agenda for research and action. 38
27840202 2017
136
The Exceptional Oncogenicity of HTLV-1. 38
28824561 2017
137
An Update on the Global Epidemic of Human T-Cell Lymphotrophic Virus Type-I (HTLV-I). 38
29773049 2017
138
Cytokine profile and proviral load among Japanese immigrants and non-Japanese infected with HTLV-1 in a non-endemic area of Brazil. 38
28376092 2017
139
Serological and Molecular Methods to Study Epidemiological Aspects of Human T-Cell Lymphotropic Virus Type 1 Infection. 38
28357658 2017
140
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation. 38
28261198 2017
141
Brain Metabolism Changes in Patients Infected with HTLV-1. 38
28293169 2017
142
Silent dissemination of HTLV-1 in an endemic area of Argentina. Epidemiological and molecular evidence of intrafamilial transmission. 38
28384180 2017
143
MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications. 38
28384290 2017
144
HTLV-1 Associated Neurological Disorders. 38
28017149 2017
145
Undifferentiated Pleomorphic Sarcoma and the Importance of Considering the Oncogenic and Immune-Suppressant Role of the Human T-Cell Lymphotropic Virus Type 1: A Case Report. 38
28596939 2017
146
Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP. 38
29312243 2017
147
HTLV-1 HBZ Viral Protein: A Key Player in HTLV-1 Mediated Diseases. 38
29312275 2017
148
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): A comparative study to identify factors that influence disease progression. 38
27871430 2016
149
Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome. 38
27553711 2016
150
Pain prevalence, characteristics and associated factors in human T-cell lymphotropic virus type 1 infected patients: a systematic review of the literature. 38
27768899 2016
151
Clonus Associated with Tropical Spastic Paraparesis. 38
27783915 2016
152
HLA-G 3'-untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis development. 38
27449667 2016
153
Peridinin, a carotenoid, inhibits proliferation and survival of HTLV-1-infected T-cell lines. 38
27499015 2016
154
Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes through the Blood-Brain Barrier. 38
27252538 2016
155
Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1). 38
27519553 2016
156
Plasmatic proinflammatory chemokines levels are tricky markers to monitoring HTLV-1 carriers. 38
26800845 2016
157
HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors. 38
26635027 2016
158
HTLV-1-associated myelopathy in a solid organ transplant recipient. 38
27268291 2016
159
Median Nerve Somatosensory Evoked Potential in HTLV-I Associated Myelopathy. 38
27382445 2016
160
Nation-wide epidemiological study of Japanese patients with rare viral myelopathy using novel registration system (HAM-net). 38
27225443 2016
161
Approach to a case of myeloneuropathy. 38
27293327 2016
162
Physalin F, a seco-steroid from Physalis angulata L., has immunosuppressive activity in peripheral blood mononuclear cells from patients with HTLV1-associated myelopathy. 38
27044821 2016
163
Suppression of Type I Interferon Production by Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax through Inhibition of IRF3 Phosphorylation. 38
26819312 2016
164
Absolute quantification of HTLV-1 basic leucine zipper factor (HBZ) protein and its plasma antibody in HTLV-1 infected individuals with different clinical status. 38
27117327 2016
165
Long Terminal Repeat Circular DNA as Markers of Active Viral Replication of Human T Lymphotropic Virus-1 in Vivo. 38
26985903 2016
166
Tax secretion from peripheral blood mononuclear cells and Tax detection in plasma of patients with human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers. 38
26241614 2016
167
Deep Sequencing Analysis of Human T Cell Lymphotropic Virus Type 1 Long Terminal Repeat 5' Region from Patients with Tropical Spastic Paraparesis/Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy and Asymptomatic Carriers. 38
26472535 2016
168
[Tropical spastic paraparesis viewed from an Iberian context]. 38
26815854 2016
169
[Tropical spastic paraparesis viewed from an Iberian context. Reply]. 38
26815855 2016
170
Neurological manifestations in individuals with HTLV-1-associated myelopathy/tropical spastic paraparesis in the Amazon. 38
26169165 2016
171
Clinical and epidemiological profiles of non-traumatic myelopathies. 38
26982994 2016
172
Expression of Alternatively Spliced Human T-Cell Leukemia Virus Type 1 mRNAs Is Influenced by Mitosis and by a Novel cis-Acting Regulatory Sequence. 38
26581997 2016
173
Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission. 38
26848683 2016
174
Genetic Markers of the Host in Persons Living with HTLV-1, HIV and HCV Infections. 38
26848682 2016
175
Human T-Cell Lymphotropic Virus Types 1 and 2 Seropositivity among Blood Donors at Mbarara Regional Blood Bank, South Western Uganda. 38
27034840 2016
176
Developing novel treatments for HTLV-1-associated myelopathy (HAM) by investigating molecular pathomechanisms. 38
27320936 2016
177
Correction: Familial Clusters of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
27028551 2016
178
Two Cases of Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis Caused by Living-Donor Renal Transplantation. 38
27777805 2016
179
HTLV-1 and HIV-1 co-infection: A case report and review of the literature. 38
27144124 2016
180
Molecular Studies of HTLV-1 Replication: An Update. 38
26828513 2016
181
Effect of Pulsed Methylprednisolone on Pain, in Patients with HTLV-1-Associated Myelopathy. 38
27077747 2016
182
Psychogenic movement disorder in human T-lymphotropic virus type 1 associated myelopathy. 38
26603645 2016
183
Family Aggregation of Human T-Lymphotropic Virus 1-Associated Diseases: A Systematic Review. 38
27840624 2016
184
HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). 38
26735971 2016
185
Barefoot Plantar Pressure Indicates Progressive Neurological Damage in Patients with Human T-Cell Lymphotropic Virus Type 1 Infection. 38
26998608 2016
186
Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth. 38
26389656 2016
187
HTLV-1, Immune Response and Autoimmunity. 38
26712781 2015
188
Infective Dermatitis in an Adult Patient With HTLV-1. 38
26588341 2015
189
Hypometabolism of watershed areas of the brain in HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
26156876 2015
190
Are lipid disorders involved in the predominance of human T-lymphotropic virus-1 infections in women? 38
26676502 2015
191
T cell receptor signaling pathway is overexpressed in CD4(+) T cells from HAM/TSP individuals. 38
26358743 2015
192
Standardization of Quantitative PCR for Human T-Cell Leukemia Virus Type 1 in Japan: a Collaborative Study. 38
26292315 2015
193
Triple Therapy with Prednisolone, Pegylated Interferon and Sodium Valproate Improves Clinical Outcome and Reduces Human T-Cell Leukemia Virus Type 1 (HTLV-1) Proviral Load, Tax and HBZ mRNA Expression in Patients with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
26174324 2015
194
Human T-lymphotropic virus 1 (HTLV-1)-associated lichenoid dermatitis induced by CD8+ T cells in HTLV-1 carrier, HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia/lymphoma. 38
26077665 2015
195
[Tropical spastic paraparesis in a non tropical region]. 38
26461129 2015
196
[Recurrent facial palsy revealing Human T-lymphotropic virus type 1 (HTLV-1) infection]. 38
25636977 2015
197
HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T cells recruitment into Central Nervous System. 38
26458945 2015
198
A Peruvian family with a high burden of HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
26392440 2015
199
Common γ-chain blocking peptide reduces in vitro immune activation markers in HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
26283355 2015
200
Human T-Lymphotropic Virus-1 Associated with Adult T-Cell Lymphoma/ Leukemia and Generalized Expansion of Palatal and Jaw Bones: A Rare Case Report. 38
26331152 2015
201
Infection with human retroviruses other than HIV-1: HIV-2, HTLV-1, HTLV-2, HTLV-3 and HTLV-4. 38
26112187 2015
202
Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence. 38
26198240 2015
203
Editorial Commentary: Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
25820278 2015
204
Neurological Manifestations in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)-Infected Individuals Without HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Longitudinal Cohort Study. 38
25820277 2015
205
High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. 38
26143070 2015
206
Seroepidemiology of human T-cell lymphotropic virus type-I in blood donors of Northeastern Iran, Sabzevar. 38
26420946 2015
207
Electrophysiological analysis shows dizziness as the first symptom in human T cell lymphotropic virus type-associated myelopathy/tropical spastic paraparesis. 38
25760424 2015
208
HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
27188208 2015
209
Prevalence of Human T-Lymphotropic Virus Types I and II in Patients With Hematological Disorders in Isfahan, Iran. 38
26301057 2015
210
Serum total antioxidant capacity status of HTLV-1 infected patients. 38
26104339 2015
211
[Intercellular transmission of HTLV-1: not all mechanisms have been revealed]. 38
26152167 2015
212
[A survey of HTLV-1 carrier clinics in Japan]. 38
26256877 2015
213
Recurrent Facial Erythema with Cytotoxic T Cell Infiltration as a Possible Reactive Eruption in a Human T-Cell Lymphotropic Virus Type 1 Carrier. 38
26078739 2015
214
Is human T-lymphotropic virus type 1 infection associated with hearing loss? 38
25354174 2015
215
The prevalence of human T-lymphotropic virus infection among blood donors in southeast China, 2004-2013. 38
25830656 2015
216
HTLV-1-associated myelopathy/tropical spastic paraparesis and peripheral neuropathy following live-donor renal transplantation. 38
25196582 2015
217
Using the International Classification of Functioning, Disability and Health as a tool for analysis of the effect of physical therapy on spasticity in HAM/TSP patients. 38
25992936 2015
218
HTLV-1-associated infective dermatitis demonstrates low frequency of FOXP3-positive T-regulatory lymphocytes. 38
25676425 2015
219
Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling. 38
25774694 2015
220
Clinical presentation of axial myopathy in two siblings with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
25884435 2015
221
Postrenal Transplant Human T-Cell Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis: A Case Report and Review of the Literature. 38
27500208 2015
222
Update on Neurological Manifestations of HTLV-1 Infection. 38
25787112 2015
223
HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL-28B Gene. 38
26609200 2015
224
Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
25470342 2015
225
High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic virus type 1-infected clones are associated with human T-cell lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis development. 38
25833232 2015
226
Cyclosporine for the treatment of HLTV-1-induced HAM/TSP: an experience from a case report. 38
25569667 2015
227
Timed walk as primary outcome measure of treatment response in clinical trials for HTLV-1-associated myelopathy: a feasibility study. 38
27965813 2015
228
Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy. 38
25104771 2015
229
Physiotherapy for human T-lymphotropic virus 1-associated myelopathy: review of the literature and future perspectives. 38
25759588 2015
230
Immunological signature of the different clinical stages of the HTLV-1 infection: establishing serum biomarkers for HTLV-1-associated disease morbidity. 38
26474234 2015
231
Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection. 38
25339765 2015
232
Atrophy, focal spinal cord lesions and alterations of diffusion tensor imaging (DTI) parameters in asymptomatic virus carriers and patients suffering from human T-lymphotrophic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
25227931 2014
233
Effect of repetitive transcranial magnetic stimulation on reducing spasticity in patients suffering from HTLV-1-associated myelopathy. 38
25462141 2014
234
A reduction of viral mRNA, proteins and induction of altered morphogenesis reveals the anti-HTLV-1 activity of the labdane-diterpene myriadenolide in vitro. 38
25539906 2014
235
A Caucasian Australian presenting with human T-lymphotropic virus type I associated myelopathy: a case report. 38
25416840 2014
236
Inflammatory manifestations of HTLV-1 and their therapeutic options. 38
25340428 2014
237
A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation. 38
25340344 2014
238
Interferon beta-1a treatment in HTLV-1-associated myelopathy/tropical spastic paraparesis: a case report. 38
25229227 2014
239
IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers. 38
25233462 2014
240
Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs. 38
24845974 2014
241
In vivo imaging of spinal cord atrophy in neuroinflammatory diseases. 38
25042583 2014
242
Molecular epidemiology and clinical features of human T cell lymphotropic virus type 1 infection in Spain. 38
24924996 2014
243
Dermatological manifestations of individuals infected with human T cell lymphotropic virus type I (HTLV-I). 38
24111739 2014
244
HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP. 38
25270762 2014
245
Temporal lesions and widespread involvement of white matter associated with multi-organ inflammatory disease in human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
24815740 2014
246
The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/γcnull (NOG) mice. 38
25163482 2014
247
HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells. 38
24960164 2014
248
Human T lymphotropic virus type 1 (HTLV-1) proviral load induces activation of T-lymphocytes in asymptomatic carriers. 38
25148903 2014
249
Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. 38
24939845 2014
250
Prevalence of human T-lymphotropic virus type 1 infection among blood donors in mainland China: a meta-analysis. 38
24865322 2014
251
Human T-cell leukemia virus type 1 and Foxp3 expression: viral strategy in vivo. 38
24792037 2014
252
Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP patients and identification of viral mutations. 38
24781526 2014
253
The use of botulinum toxin type A in the treatment of HTLV-1-associated overactive bladder refractory to conventional therapy. 38
25229299 2014
254
Inferences about the global scenario of human T-cell lymphotropic virus type 1 infection using data mining of viral sequences. 38
24863974 2014
255
Vaccination against δ-retroviruses: the bovine leukemia virus paradigm. 38
24956179 2014
256
Genes related to antiviral activity, cell migration, and lysis are differentially expressed in CD4(+) T cells in human t cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patients. 38
24041428 2014
257
[Tropical spastic paraparesis: a report of a new case in Spain]. 38
24915034 2014
258
Pentosan polysulfate treatment ameliorates motor function with increased serum soluble vascular cell adhesion molecule-1 in HTLV-1-associated neurologic disease. 38
24671717 2014
259
The 5' untranslated region of the human T-cell lymphotropic virus type 1 mRNA enables cap-independent translation initiation. 38
24623421 2014
260
Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
24704970 2014
261
Seroepidemiology of human T-cell lymphotropic virus type-1 (HTLV1) in Mashhad. 38
25168999 2014
262
Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis. 38
23943469 2014
263
Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients. 38
24321043 2014
264
Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis. 38
24352466 2014
265
Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru. 38
24262672 2014
266
CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis. 38
24472094 2014
267
HTLV-I-associated myelopathy/tropical spastic paraparesis: semiautomatic quantification of spinal cord atrophy from 3-dimensional MR images. 38
22303896 2014
268
Proprioceptive neuromuscular facilitation in HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
24603733 2014
269
Familial clusters of HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
24802839 2014
270
Investigating human T cell lymphotropic retrovirus (HTLV) Tax function with molecular and immunophenotypic techniques. 38
24158832 2014
271
Tropical myelopathies. 38
24365434 2014
272
Molecular characterization of human T-cell lymphotropic virus type 1 full and partial genomes by Illumina massively parallel sequencing technology. 38
24686382 2014
273
Seroprevalence of human T-lymphotropic virus antibodies among patients with lymphoid malignancies at a tertiary center in Lagos, Nigeria. 38
25228827 2014
274
Clinical features of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in northeast Iran. 38
23568138 2013
275
Balancing the robustness and predictive performance of biomarkers. 38
23909374 2013
276
Increased seroreactivity to HERV-K10 peptides in patients with HTLV myelopathy. 38
24365054 2013
277
HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replication. 38
24109220 2013
278
High prevalence of skin disorders among HTLV-1 infected individuals independent of clinical status. 38
24244779 2013
279
Association between urinary symptoms and quality of life in HTLV-1 infected subjects without myelopathy. 38
24456778 2013
280
Contribution of Galvanic Vestibular Stimulation for the Diagnosis of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. 38
24285967 2013
281
Clustering of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated with HTLV-1 (IDH) in Salvador, Bahia, Brazil. 38
23932323 2013
282
Association between HLA alleles and HAM/TSP in individuals infected with HTLV-1. 38
23835632 2013
283
Molecular study of HBZ and gp21 human T cell leukemia virus type 1 proteins isolated from different clinical profile infected individuals. 38
23800288 2013
284
Lack of recall response to Tax in ATL and HAM/TSP patients but not in asymptomatic carriers of human T-cell leukemia virus type 1. 38
23888327 2013
285
Incidence of human T cell lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis in a long-term prospective cohort study of initially asymptomatic individuals in Brazil. 38
23617363 2013
286
Increased osteopontin expression in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patient cells is associated with IL-17 expression. 38
23756056 2013
287
Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: from structural insights to post-transcriptional regulatory roles. 38
23247072 2013
288
Standardisation of Western blotting to detect HTLV-1 antibodies synthesised in the central nervous system of HAM/TSP patients. 38
24037195 2013
289
Highlights on distinctive structural and functional properties of HTLV Tax proteins. 38
24058363 2013
290
Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy. 38
23892452 2013
291
Modulation of glutathione intracellular levels alters the spontaneous proliferation of lymphocyte from HTLV-1 infected patients. 38
23669236 2013
292
HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression. 38
24068936 2013
293
An altered maturation and adhesion phenotype of dendritic cells in diseased individuals compared to asymptomatic carriers of human T cell leukemia virus type 1. 38
23750452 2013
294
Human T cell leukemia virus type I tax-induced IκB-ζ modulates tax-dependent and tax-independent gene expression in T cells. 38
24027435 2013
295
Efficacy of prosultiamine treatment in patients with human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: results from an open-label clinical trial. 38
23945290 2013
296
Therapeutic benefits of an oral vitamin B1 derivative for human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
23945332 2013
297
Human T-lymphotropic virus type 1 non-structural proteins: Requirements for latent infection. 38
23651172 2013
298
Increased expression of OX40 is associated with progressive disease in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
23651542 2013
299
Tropical spastic paraparesis treated with Combivir (lamivudine-zidovudine). 38
23477875 2013
300
[Pathophysiology, treatment and biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)]. 38
23777097 2013
301
Altered expression of degranulation-related genes in CD8+ T cells in human T lymphotropic virus type I infection. 38
23301858 2013
302
Interferon-α (IFN-α) suppresses HTLV-1 gene expression and cell cycling, while IFN-α combined with zidovudine induces p53 signaling and apoptosis in HTLV-1-infected cells. 38
23688327 2013
303
Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia. 38
23538341 2013
304
Seroepidemiology of human T-cell lymphotropic virus 1 infection in hemodialysis patients: should we be concerned about it? 38
23689148 2013
305
Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats. 38
23622267 2013
306
Testing the vestibular evoked myogenic potential (VEMP) to identify subclinical neurological alterations in different phases of human T-lymphotropic virus type 1 infection. 38
23267739 2013
307
Falls in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
23165507 2013
308
Effects of Danazol on Clinical Improvement of Patients with Human T-cell Lymphotropic Virus Type I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP): A Placebo-Controlled Clinical Trial. 38
24470864 2013
309
Association of IL-10 Gene Polymorphisms and Human T Lymphotropic Virus Type I-Associated Myelopathy/tropical Spastic Paraparesis in North-East of Iran (Mashhad). 38
24470873 2013
310
The Impact of Immune Response on HTLV-I in HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). 38
24470869 2013
311
Molecular characterization of HTLV-1 gp46 glycoprotein from health carriers and HAM/TSP infected individuals. 38
23510700 2013
312
"HTLV-I Infection" Twenty-Year Research in Neurology Department of Mashhad University of Medical Sciences. 38
24470862 2013
313
Population-based Seroprevalence of HTLV-I Infection in Golestan Province, South East of Caspian Sea, Iran. 38
24470867 2013
314
Human T cell lymphotropic virus type 1 viral load variability and long-term trends in asymptomatic carriers and in patients with human T cell lymphotropic virus type 1-related diseases. 38
22894552 2013
315
Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals. 38
23405908 2013
316
CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
24130912 2013
317
Co-presentation of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis and adult-onset infective dermatitis associated with HTLV-1 infection. 38
23278610 2013
318
Invasion of histiocytic sarcoma into the spinal cord of HTLV-1 tax transgenic mice with HTLV-1-associated myelopathy/tropical spastic paraparesis-like disease. 38
23924924 2013
319
Proviral load and the balance of serum cytokines in HTLV-1-asymptomatic infection and in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
23022356 2013
320
[HTLV-1: Recent topics in epidemiologic, basic and clinical research]. 38
25366051 2013
321
Expansion in CD39⁺ CD4⁺ immunoregulatory t cells and rarity of Th17 cells in HTLV-1 infected patients is associated with neurological complications. 38
23409198 2013
322
Schistosoma antigens downmodulate the in vitro inflammatory response in individuals infected with human T cell lymphotropic virus type 1. 38
23752304 2013
323
Human endogenous retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods. 38
23305161 2013
324
Cerebrospinal fluid neopterin, but not osteopontin, is a valuable biomarker for the treatment response in patients with HTLV-I-associated myelopathy. 38
24088752 2013
325
Lack of evidence to support the association of a single IL28B genotype SNP rs12979860 with the HTLV-1 clinical outcomes and proviral load. 38
23259930 2012
326
Immunological and viral features in patients with overactive bladder associated with human T-cell lymphotropic virus type 1 infection. 38
22997085 2012
327
HTLV-1-associated infective dermatitis: updates on the pathogenesis. 38
23163646 2012
328
Comparison of HTLV-associated myelopathy (HAM) in HIV-positive and HIV-negative patients at a tertiary South African hospital. 38
23237124 2012
329
Impact of depression on quality of life in people living with human T cell lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil. 38
22109110 2012
330
Immunopathogenesis and neurological manifestations associated to HTLV-1 infection. 38
23152334 2012
331
Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients. 38
22990976 2012
332
The impact of interferon-alpha treatment on clinical and immunovirological aspects of HTLV-1-associated myelopathy in northeast of Iran. 38
22727800 2012
333
Oral health profile in patients infected with HTLV-1: clinical findings, proviral load, and molecular analysis from HTLV-1 in saliva. 38
22825822 2012
334
Antibody transfection into neurons as a tool to study disease pathogenesis. 38
23051967 2012
335
[HTLV-1-associated myelopathy/tropical spastic paraparesis: a differential diagnosis in multiple sclerosis]. 38
22588562 2012
336
In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection. 38
22609443 2012
337
Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses. 38
22876852 2012
338
Human T-lymphotropic virus proteins and post-translational modification pathways. 38
24175216 2012
339
Interleukin-18 and interferon-gamma polymorphisms are implicated on proviral load and susceptibility to human T-lymphotropic virus type 1 infection. 38
22587568 2012
340
Mechanisms of human T-lymphotropic virus type 1 transmission and disease. 38
22819021 2012
341
Development of tropical spastic paraparesis in human T-lymphotropic virus type 1 carriers is influenced by interleukin 28B gene polymorphisms. 38
22460962 2012
342
Human T-cell leukaemia/lymphoma virus type-1 associated myeloneuropathies--a Caribbean perspective. 38
23240477 2012
343
Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells. 38
22589473 2012
344
Evolution of HTLV-1 proviral load in patients from Salvador, Brazil. 38
22846124 2012
345
Human T-lymphotropic virus type I (HTLV-I)-specific CD8+ cells accumulate in the lungs of patients infected with HTLV-I with pulmonary involvement. 38
22585731 2012
346
Comparison between the spastic paraplegia rating scale, Kurtzke scale, and Osame scale in the tropical spastic paraparesis/myelopathy associated with HTLV. 38
22760127 2012
347
HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals. 38
22647666 2012
348
[The current and future approaches to the treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)]. 38
22568157 2012
349
Monitoring the HTLV-1 proviral load in the peripheral blood of asymptomatic carriers and patients with HTLV-associated myelopathy/tropical spastic paraparesis from a Brazilian cohort: ROC curve analysis to establish the threshold for risk disease. 38
22337307 2012
350
Quality of life in patients with HTLV-I associated myelopathy/tropical spastic paraparesis. 38
22323336 2012
351
HAM/TSP: association between white matter lesions on magnetic resonance imaging, clinical and cerebrospinal fluid findings. 38
22510735 2012
352
Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome. 38
22510736 2012
353
Nuclear export and expression of human T-cell leukemia virus type 1 tax/rex mRNA are RxRE/Rex dependent. 38
22318152 2012
354
Primary brain T-cell lymphoma in an HTLV-1 serologically positive male. 38
22118868 2012
355
Blood-brain barrier and retroviral infections. 38
22460635 2012
356
Tropical spastic paraparesis and HTLV-1 associated myelopathy: clinical, epidemiological, virological and therapeutic aspects. 38
22405461 2012
357
Helminthic infection and the risk of neurologic disease progression in HTLV-1. 38
22237002 2012
358
Quantitative differences in HTLV-I antibody responses: classification and relative risk assessment for asymptomatic carriers and ATL and HAM/TSP patients from Jamaica. 38
22318200 2012
359
[Intermediate uveitis due to human T-cell lymphotropic virus type 1]. 38
22341358 2012
360
Possible implication of NFKB1A and NKG2D genes in susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian patients infected with HTLV-1. 38
22170554 2012
361
Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease. 38
22335964 2012
362
Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis. 38
22720101 2012
363
Clinical pathophysiology of human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis. 38
23162542 2012
364
Immunopathogenesis of human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: recent perspectives. 38
23198155 2012
365
Altered Prion protein expression pattern in CSF as a biomarker for Creutzfeldt-Jakob disease. 38
22558368 2012
366
Comparison of the Genetic Organization, Expression Strategies and Oncogenic Potential of HTLV-1 and HTLV-2. 38
23213551 2012
367
Overview on HTLV-1 p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis. 38
23248621 2012
368
Interferon Beta-1a Improves Urinary Symptoms, Reduces Proviral Load, and Modifies the Immune Response in a Patient with HAM/TSP. 38
22953092 2012
369
The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation. 38
22429853 2012
370
Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy. 38
22291590 2012
371
Detection of human T-cell lymphotropic virus type 1 in plasma samples. 38
21924305 2012
372
HTLV-1 uveitis. 38
22837757 2012
373
What we are learning on HTLV-1 pathogenesis from animal models. 38
22969759 2012
374
The roles of acquired and innate immunity in human T-cell leukemia virus type 1-mediated diseases. 38
22969761 2012
375
Leukotrienes are upregulated and associated with human T-lymphotropic virus type 1 (HTLV-1)-associated neuroinflammatory disease. 38
23284797 2012
376
Complex role of microRNAs in HTLV-1 infections. 38
23251140 2012
377
Animal models on HTLV-1 and related viruses: what did we learn? 38
23049525 2012
378
Antiviral effect of raltegravir on HTLV-1 carriers. 38
21965433 2012
379
Kinetic characterization of newly discovered inhibitors of various constructs of human T-cell leukemia virus-1 (HTLV-1) protease and their effect on HTLV-1-infected cells. 38
22436331 2012
380
Molecular epidemiology of endemic human T-lymphotropic virus type 1 in a rural community in Guinea-Bissau. 38
22720106 2012
381
Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy. 38
22808032 2012
382
Cellular Factors Involved in HTLV-1 Entry and Pathogenicit. 38
22737146 2012
383
Ascorbic acid has superior ex vivo antiproliferative, cell death-inducing and immunomodulatory effects over IFN-α in HTLV-1-associated myelopathy. 38
22848768 2012
384
HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways. 38
23226145 2012
385
Pathogenic mechanisms of neurodegeneration based on the phenotypic expression of progressive forms of immune-mediated neurologic disease. 38
30890887 2012
386
Safety of long-term treatment of HAM/TSP patients with valproic acid. 38
21998206 2011
387
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP): still an obscure disease. 38
22300227 2011
388
Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers. 38
22151736 2011
389
[Genome epidemiology and tropical spastic paraparesis associated with human T-cell lymphotropic virus type 1]. 38
22262268 2011
390
A crippling virus: diagnosing tropical spastic paraparesis. 38
22023230 2011
391
Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a Peruvian population. 38
21453202 2011
392
Programmed death-1 (PD-1)/PD-1 ligand pathway-mediated immune responses against human T-lymphotropic virus type 1 (HTLV-1) in HTLV-1-associated myelopathy/tropical spastic paraparesis and carriers with autoimmune disorders. 38
21851845 2011
393
Molecular mechanisms of HTLV-1 infection and pathogenesis. 38
21953273 2011
394
Recruiting individuals into the HTLV cohort study in the United Kingdom: clinical findings and challenges in the first six years, 2003 to 2009. 38
22115046 2011
395
Effect of TNF-α production inhibitors on the production of pro-inflammatory cytokines by peripheral blood mononuclear cells from HTLV-1-infected individuals. 38
22011961 2011
396
Activation of LTRs from different human endogenous retrovirus (HERV) families by the HTLV-1 tax protein and T-cell activators. 38
22163338 2011
397
Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
21992623 2011
398
HTLV-1 associated myelopathy/tropical spastic paraparesis: how far have we come? 38
22519224 2011
399
Molecular and clinical effects of betamethasone in human T-cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients. 38
21739457 2011
400
Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes. 38
21671254 2011
401
Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease. 38
21994794 2011
402
Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes. 38
21505188 2011
403
Human T-lymphotropic virus 1 (HTLV-1) infection--dermatological implications. 38
21781059 2011
404
Development of [Ile⁴⁰]HTLV-I protease inhibition assay using novel fluorogenic and chromogenic substrate. 38
21574213 2011
405
The prevalence and significance of HTLV-I/II seroindeterminate Western blot patterns. 38
21994781 2011
406
[Virological aspects of HTLV-1 infection and new therapeutical concepts]. 38
21607661 2011
407
[Human retrovirus HTLV-1: descriptive and molecular epidemiology, origin, evolution, diagnosis and associated diseases]. 38
21796326 2011
408
Modulation of innate immune responses during human T-cell leukemia virus (HTLV-1) pathogenesis. 38
21924945 2011
409
Human T cell lymphotropic virus type 1 (HTLV-1) proviral load of HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients according to new diagnostic criteria of HAM/TSP. 38
21567429 2011
410
Prospects for the management of human T-cell lymphotropic virus type 1-associated myelopathy. 38
21799534 2011
411
Molecular determinants of human T-lymphotropic virus type 1 transmission and spread. 38
21994774 2011
412
Khorasan Disease: Prevalence of HTLV-I Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) In West Azarbaijan from 2004 to 2007. 38
22737507 2011
413
A case report of HTLV-I associated myelopathy presenting with cerebellar ataxia and nystagmus. 38
21035292 2011
414
Inhibition of expression of HTLV-1 structural genes mediated by short hairpin RNA in vitro. 38
21737637 2011
415
Clinical manifestations in individuals with recent diagnosis of HTLV type I infection. 38
21388871 2011
416
Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles. 38
21392990 2011
417
Prevalence of human T-cell lymphotropic virus type 1 and 2 among patients with malignant hematological diseases in south Chile. 38
21328393 2011
418
Reduced Tim-3 expression on human T-lymphotropic virus type I (HTLV-I) Tax-specific cytotoxic T lymphocytes in HTLV-I infection. 38
21402546 2011
419
HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications. 38
21541358 2011
420
Low CD4/CD8 T-cell ratio associated with inflammatory arthropathy in human T-cell leukemia virus type I Tax transgenic mice. 38
21483764 2011
421
Double control systems for human T-cell leukemia virus type 1 by innate and acquired immunity. 38
21219540 2011
422
Genetic characterization of human T-cell lymphotropic virus type 1 in Mozambique: transcontinental lineages drive the HTLV-1 endemic. 38
21532745 2011
423
Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders. 38
21264872 2011
424
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics. 38
21282516 2011
425
Prevalence of peripheral neuropathy in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
21510232 2011
426
Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease. 38
21212284 2011
427
Characteristics of Chronic Pain and Its Impact on Quality of Life of Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). 38
20842011 2011
428
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP. 38
21106989 2011
429
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. 38
21347344 2011
430
Ethnoepidemiology of HTLV-1 related diseases: ethnic determinants of HTLV-1 susceptibility and its worldwide dispersal. 38
21205073 2011
431
Isokinetic trunk and knee muscle strengths and gait performance in walking patients with T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP). 38
25792894 2011
432
Fulminant myelopathy following neurogenic proximal weakness associated with human T-cell lymphotropic virus type I infection. 38
21498943 2011
433
Human T-lymphotrophic virus type 1-associated infective dermatitis: a comprehensive review. 38
20691499 2011
434
Monocytes from HTLV-1-infected patients are unable to fully mature into dendritic cells. 38
20956799 2011
435
Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease. 38
21311112 2011
436
Human T-Lymphotropic Virus (HTLV) Type I in vivo Integration in Oral Keratinocytes. 38
24031637 2011
437
Murine FLT3 ligand-derived dendritic cell-mediated early immune responses are critical to controlling cell-free human T cell leukemia virus type 1 infection. 38
21115731 2011
438
Route of primary HTLV-1 infection regulates HTLV-1 distribution in reservoir organs of infected mice. 38
22977475 2011
439
Sphincter abnormality in polytransfused patient due to paroxysmal nocturnal hemoglobinuria (PNH): initial manifestation of tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM). 38
21243260 2010
440
Neuromyelitis optica associated with subacute human T-lymphotropic virus type 1 infection. 38
20638847 2010
441
Absence of consistent association between human leukocyte antigen-I and -II alleles and human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis risk in an HTLV-1 French Afro-Caribbean population. 38
20851016 2010
442
Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission. 38
21076035 2010
443
Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors. 38
20587783 2010
444
HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1). 38
21079688 2010
445
In vivo fluctuation of Tax, Foxp3, CTLA-4, and GITR mRNA expression in CD4(+)CD25(+) T cells of patients with human T-lymphotropic virus type 1-associated myelopathy. 38
20945034 2010
446
[Investigation of anti-HTLV I/II seroprevalence in healthy blood donors in Izmir region, Turkey]. 38
21063970 2010
447
Neuropathology of HTLV-1-associated myelopathy (HAM/TSP): The 50th Anniversary of Japanese Society of Neuropathology. 38
20573027 2010
448
Cutaneous manifestations associated with HTLV-1 infection. 38
20883400 2010
449
HTLV-1 p13, a small protein with a busy agenda. 38
20332002 2010
450
Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis. 38
21994719 2010
451
Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru. 38
20483367 2010
452
Correlation of HTLV-1 Tax genetic diversity with HTLV-1 associated myelopathy/tropical spastic paraparesis progression and HTLV-1a genotypes in an HTLV-1 endemic region in Argentina. 38
20572090 2010
453
[Current situation of human immunodeficiency virus type 2 and Human T lymphotropic virus in Spain]. 38
20570417 2010
454
Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. 38
20600105 2010
455
Mouse models of human T lymphotropic virus type-1-associated adult T-cell leukemia/lymphoma. 38
20442421 2010
456
Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases. 38
20610824 2010
457
Patterns of non-traumatic myelopathies in Yaounde (Cameroon): a hospital based study. 38
20581141 2010
458
Diagnostic tool based on an HTLV-1-Tax expression system in eukaryotic cells using a poxvirus vector. 38
20219542 2010
459
Depletion of dendritic cells enhances susceptibility to cell-free infection of human T cell leukemia virus type 1 in CD11c-diphtheria toxin receptor transgenic mice. 38
20382884 2010
460
Prevalence of erectile dysfunction in HTLV-1-infected patients and its association with overactive bladder. 38
20189229 2010
461
Childhood-onset HAM/TSP with progressive cognitive impairment. 38
20076981 2010
462
Multistability in a model for CTL response to HTLV-I infection and its implications to HAM/TSP development and prevention. 38
20041353 2010
463
Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patients. 38
20087941 2010
464
Oral manifestations of human T-cell lymphotropic virus infection in adult patients from Brazil. 38
20374504 2010
465
Low-back pain in HTLV-I-associated myelopathy/tropical spastic paraparesis: nociceptive or neuropathic? 38
19581917 2010
466
Neuraminidase enhances the initial steps of human T-cell leukemia virus type 1 replication. 38
19892032 2010
467
Human T cell leukemia virus type 1 infection drives spontaneous proliferation of natural killer cells. 38
20640055 2010
468
Clinical studies on rising and re-rising neurological diseases in Japan--a personal contribution. 38
20431261 2010
469
Immunogenetics and the Pathological Mechanisms of Human T-Cell Leukemia VirusType 1- (HTLV-1-)Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). 38
20169122 2010
470
[Seroprevalence of HTLV-1/2 in blood donors from Misiones Province]. 38
20228028 2010
471
HTLV-1 related knowledge, attitude and behaviour patterns among mothers who participated in the Jamaica Breastfeeding Intervention Study (1996-2000). 38
20931911 2010
472
The motor evoked potential in AIDS and HAM/TSP: state of the evidence. 38
20069238 2009
473
High expression of CD244 and SAP regulated CD8 T cell responses of patients with HTLV-I associated neurologic disease. 38
19997502 2009
474
Lower numbers of circulating Natural Killer T (NK T) cells in individuals with human T lymphotropic virus type 1 (HTLV-1) associated neurological disease. 38
19778295 2009
475
Suppression of human T-cell leukemia virus I gene expression by pokeweed antiviral protein. 38
19748897 2009
476
Changes in T cell phenotype and activated MAPKs are correlated to impaired cellular responses to antigens and glucocorticoids during HTLV-I infection. 38
19766325 2009
477
Early neurologic abnormalities associated with human T-cell lymphotropic virus type 1 infection in a cohort of Peruvian children. 38
19628219 2009
478
Ocular lesions in HTLV-1 infected patients from Salvador, State of Bahia: the city with the highest prevalence of this infection in Brazil. 38
20209345 2009
479
Is human T cell lymphotropic type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) syndrome a neglected disease? 38
19936247 2009
480
Phosphorylation regulates human T-cell leukemia virus type 1 Rex function. 38
19919707 2009
481
The elevated interferon gamma production is an important immunological marker in HAM/TSP pathogenesis. 38
19751276 2009
482
Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders. 38
19666871 2009
483
IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian population. 38
19740339 2009
484
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients. 38
19838519 2009
485
Induction of IL-10- and IFN-gamma-producing T-cell responses by autoreactive T-cells expressing human T-cell leukemia virus type I Tax. 38
19654198 2009
486
Neurologic abnormalities in HTLV-I- and HTLV-II-infected individuals without overt myelopathy. 38
19738173 2009
487
Comparative study of CSF neurofilaments in HTLV-1-associated myelopathy/tropical spastic paraparesis and other neurological disorders. 38
19678766 2009
488
High HTLV-1 proviral load, a marker for HTLV-1 associated myelopathy/tropical spastic paraparesis, is also detected in patients with infective dermatitis associated with HTLV-1. 38
19578703 2009
489
Abnormally high levels of virus-infected IFN-gamma+ CCR4+ CD4+ CD25+ T cells in a retrovirus-associated neuroinflammatory disorder. 38
19654865 2009
490
Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review. 38
20352020 2009
491
Infective dermatitis has similar immunological features to human T lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis. 38
19438598 2009
492
Therapeutic strategies in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
20021347 2009
493
Gene activation therapy: from the BLV model to HAM/TSP patients. 38
19482696 2009
494
Stromal cell-mediated suppression of human T-cell leukemia virus type 1 expression in vitro and in vivo by type I interferon. 38
19264779 2009
495
Neurological aspects of HIV/human T lymphotropic virus coinfection. 38
19529747 2009
496
DC-SIGN (CD209) gene promoter polymorphisms in a Brazilian population and their association with human T-cell lymphotropic virus type 1 infection. 38
19264667 2009
497
[Immunopathogenesis and treatment of the myelopathy associated to the HTLV-I virus]. 38
19206063 2009
498
Candidate polyanionic microbicides inhibit human T-cell lymphotropic virus type 1 receptor interactions, cell-free infection, and cell-cell spread. 38
19047654 2009
499
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
19228429 2009
500
Population differences in immune marker profiles associated with human T-lymphotropic virus type I infection in Japan and Jamaica. 38
18989900 2009
501
Disulfide-mediated apoptosis of human T-lymphotrophc virus type-I (HTLV-I)-infected cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
19578238 2009
502
HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP): the role of HTLV-I-infected Th1 cells in the pathogenesis, and therapeutic strategy. 38
19618340 2009
503
Neurological morbidity among human T-lymphotropic-virus-type-1-infected individuals in a rural West African population. 38
18977823 2009
504
Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease. 38
19273122 2009
505
Protein-protein interactions and gene expression regulation in HTLV-1 infected cells. 38
19273340 2009
506
Association of HTLV-I with Arnold Chiari syndrome and syringomyelia. 38
19287845 2008
507
Correlation between polymorphisms at interleukin-6 but not at interleukin-10 promoter and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Brazilian individuals. 38
19040291 2008
508
[Autoimmune syndrome in the tropical spastic paraparesis/myelopathy associated with human T-lymphotropic virus infections]. 38
19462556 2008
509
Post-translational glycosylation of target proteins implicate molecular mimicry in the pathogenesis of HTLV-1 associated neurological disease. 38
18793806 2008
510
Alteration of blood-brain barrier integrity by retroviral infection. 38
19008946 2008
511
Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy. 38
18989817 2008
512
Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
18937847 2008
513
Low risk of tropical spastic paraparesis/human T lymphotropic virus type 1-associated myelopathy development among persons aged >50 years. 38
18680397 2008
514
Two Babinski signs in seropositive (HAM) and seronegative tropical spastic paraparesis. 38
18949264 2008
515
Impaired function of human T-lymphotropic virus type 1 (HTLV-1)-specific CD8+ T cells in HTLV-1-associated neurologic disease. 38
18502825 2008
516
Retrovirally induced CTL degranulation mediated by IL-15 expression and infection of mononuclear phagocytes in patients with HTLV-I-associated neurologic disease. 38
18509087 2008
517
Design of potent aspartic protease inhibitors to treat various diseases. 38
18763714 2008
518
HTLV type 1 genetic types among native descendants in Argentina. 38
18657044 2008
519
Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy. 38
18639344 2008
520
Treatment of HTLV-I-associated myelopathy/tropical spastic paraparesis: toward rational targeted therapy. 38
18657726 2008
521
The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
18664281 2008
522
Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme. 38
18558491 2008
523
HTLV-1 tax-induced NF-kappaB activation is synergistically enhanced by 12-O-tetradecanoylphorbol-13-acetate: mechanism and implications for Tax oncogenicity. 38
18425496 2008
524
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) inflammatory network. 38
18691139 2008
525
Treatment of postpartum depression with psychotic features in a patient with tropical spastic paraparesis. 38
18413682 2008
526
Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease. 38
18326816 2008
527
Corticosteroid therapy in TSP/HAM patients: the results from a 10 years open cohort. 38
18258264 2008
528
[Infectious agents as the triggers for the pathogenesis of the neuroimmunological disorders]. 38
18540348 2008
529
HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches. 38
18421579 2008
530
Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation. 38
18541021 2008
531
Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. 38
18544167 2008
532
[Salivary and lacrymal gland disorders and HTLV-1 infection]. 38
18374956 2008
533
Human T-lymphotropic virus 1 neurologic disease. 38
18579023 2008
534
Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties. 38
18400502 2008
535
Vestibular-evoked myogenic potential (VEMP) to evaluate cervical myelopathy in human T-cell lymphotropic virus type I infection. 38
18469690 2008
536
Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo. 38
18474092 2008
537
Significantly increased antibody response to heterogeneous nuclear ribonucleoproteins in cerebrospinal fluid of multiple sclerosis patients but not in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
18444084 2008
538
Increased frequency of CD4+T cells expressing fractalkine receptor CX3CR1 in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), but its AIDS susceptible polymorphisms are not associated with the disease. 38
17884099 2008
539
Presence of tropical spastic paraparesis/human T-cell lymphotropic virus type 1-associated myelopathy (TSP/HAM)-like among HIV-1-infected patients. 38
18205234 2008
540
[Neurological symptoms and disability in HTLV-1 associated myelopathy]. 38
18322825 2008
541
HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP. 38
18369476 2008
542
Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma. 38
18173359 2008
543
[Intravenous methylprednisolone in tropical spastic paraparesis]. 38
18297629 2008
544
Increased microvessel density in involved organs from patients with HTLV-I associated adult T cell leukemia lymphoma. 38
18231912 2008
545
Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan. 38
18091562 2008
546
Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders. 38
18195496 2008
547
Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: an in vitro model of HTLV-I-induced disease. 38
19399337 2008
548
HTLV-I production based on activation of integrin/ligand signaling in HTLV-I-infected T cell lines derived from HAM/TSP patients. 38
18552504 2008
549
Truncated MTA-1: a pitfall in ELISA-based immunoassay of HTLV-1 infection. 38
18566680 2008
550
Incidence and clinical significances of human T-cell lymphotropic virus type I-associated myelopathy with T2 hyperintensity on spinal magnetic resonance images. 38
18981631 2008
551
Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide. 38
18190256 2007
552
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP. 38
18160007 2007
553
HTLV-I and neurological disease: from tropical spastic paraparesis to HTLV-I-associated myelopathy: what next? 38
18090720 2007
554
Human T lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis in an HIV-positive patient coinfected with human T lymphotropic virus type 2 following initiation of antiretroviral therapy. 38
17918071 2007
555
Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. 38
17717136 2007
556
Identification of human T cell leukemia virus type 1 tax amino acid signals and cellular factors involved in secretion of the viral oncoprotein. 38
17897946 2007
557
A case of human T lymphotropic virus type I-associated synovial swelling. 38
17968339 2007
558
Subacute progression of human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
17994432 2007
559
Frequent HTLV-1 infection in the offspring of Peruvian women with HTLV-1-associated myelopathy/tropical spastic paraparesis or strongyloidiasis. 38
18078583 2007
560
Adult T-cell leukemia/lymphoma and HTLV-1. 38
20425378 2007
561
HTLV-1a tax gene and long terminal repeat sequences from Argentinean strains reveal disagreement with tax restriction fragment length polymorphism subtyping. 38
17919108 2007
562
Risk of human T-lymphotropic virus type I-associated diseases in Jamaica with common HLA types. 38
17437273 2007
563
[Immunohistochemistry of degenerative changes in the central nervous system in spastic paraparesis associated to human T lymphotropic virus type I (HTLV-I)]. 38
18064368 2007
564
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization. 38
17675520 2007
565
High production of RANTES and MIP-1alpha in the tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM). 38
17588676 2007
566
T CD4+ cells count among patients co-infected with human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type 1 (HTLV-1): high prevalence of tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM). 38
17823752 2007
567
Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1. 38
17442856 2007
568
[Imported tropical spastic paraparesis]. 38
17568526 2007
569
Abnormalities of spinal magnetic resonance images implicate clinical variability in human T-cell lymphotropic virus type I-associated myelopathy. 38
17613716 2007
570
Temporal dynamics of human T-lymphotropic virus type I tax mRNA and proviral DNA load in peripheral blood mononuclear cells of human T-lymphotropic virus type I-associated myelopathy patients. 38
17457906 2007
571
Association between HLA-DRB1*01 and HLA-Cw*08 and outcome following HTLV-I infection. 38
17652849 2007
572
In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection. 38
17483473 2007
573
[Cloning and expression of the transmembranic glycoprotein from human T cell lymphotropic virus in a prokaryotic system]. 38
17653460 2007
574
Genetic stability of human T lymphotropic virus type I despite antiviral pressures by CTLs. 38
17442981 2007
575
Urinary symptoms associated with human T-cell lymphotropic virus type I infection: evidence of urinary manifestations in large group of HTLV-I carriers. 38
17482910 2007
576
Induction of pro-inflammatory cytokines by human T-cell leukemia virus type-1 Tax protein as determined by multiplexed cytokine protein array analyses of human dendritic cells. 38
17391906 2007
577
Interaction of HTLV-1 Tax protein with calreticulin: implications for Tax nuclear export and secretion. 38
17395420 2007
578
HTLV-I alters the multidrug resistance associated protein 1 (ABCC1/MRP1) expression and activity in human T cells. 38
17363073 2007
579
Human T-lymphotropic virus 1: recent knowledge about an ancient infection. 38
17376384 2007
580
Urinary and sexual manifestations of patients infected by HTLV-I. 38
17505705 2007
581
Human T-cell leukemia virus type I induces adult T-cell leukemia: from clinical aspects to molecular mechanisms. 38
17387298 2007
582
Human T lymphotropic virus type 1 (HTLV-1) proviral load in asymptomatic carriers, HTLV-1-associated myelopathy/tropical spastic paraparesis, and other neurological abnormalities associated with HTLV-1 infection. 38
17278060 2007
583
Clinical manifestations associated with HTLV type I infection: a cross-sectional study. 38
17411369 2007
584
Proinflammatory cytokine gene induction by human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 Tax in primary human glial cells. 38
17121800 2007
585
Blockade of IL-2 receptor suppresses HTLV-I and IFN-gamma expression in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
17409595 2007
586
Differential diagnosis of multiple sclerosis. 38
17531852 2007
587
Anti-Tac (daclizumab, Zenapax) in the treatment of leukemia, autoimmune diseases, and in the prevention of allograft rejection: a 25-year personal odyssey. 38
17216565 2007
588
Disability and determinants of gait performance in tropical spastic paraparesis/HTLV-I associated myelopathy (HAM/TSP). 38
16568145 2007
589
Differentiation of HAM/TSP from patients with multiple sclerosis infected with HTLV-I. 38
17224575 2007
590
HTLV-1 Tax and adult T-cell leukemia. 38
17127397 2007
591
HTLV-I Infection: virus structure, immune response to the virus and genetic association studies in HTLV-I-infected individuals. 38
17237568 2006
592
Hypergammaglobulinemia and corneal opacities in patients with human T-cell lymphotrophic virus type-1. 38
17157606 2006
593
Tropical spastic paraparesis and polymyositis--a still unfolding story. 38
17691249 2006
594
Human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis: viral load and muscle tone are correlated. 38
17162662 2006
595
The HTLV-1 neurological complex. 38
17110288 2006
596
SYBR Green-based quantitation of human T-lymphotropic virus type 1 proviral load in Peruvian patients with neurological disease and asymptomatic carriers: influence of clinical status, sex, and familial relatedness. 38
17162661 2006
597
Proviral load and immune markers associated with human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Peru. 38
17034574 2006
598
Dermatological findings in 3 generations of a family with a high prevalence of human T cell lymphotropic virus type 1 infection in Brazil. 38
17051489 2006
599
Manifestations of the human T-cell lymphotropic virus type I infection in childhood and adolescence. 38
17171202 2006
600
Natural history of human T-lymphotropic virus 1-associated myelopathy: a 14-year follow-up study. 38
17101824 2006
601
Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). 38
17067261 2006
602
Brain volume measurements in patients with human T-cell lymphotropic virus-1-associated tropical spastic paraparesis. 38
17065127 2006
603
Distribution of human T cell lymphotropic virus type 1 (HTLV-1) subtypes in Brazil: genetic characterization of LTR and tax region. 38
17067264 2006
604
Tropical spastic paraparesis from northern India. 38
17212030 2006
605
Human T-cell lymphotropic virus type I (HTLV-I) confirmed by PCR-Southern blot and sequencing analysis in a woman with tropical spastic paraparesis. 38
16998729 2006
606
[Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará]. 38
17160333 2006
607
Combined antiviral-immunosuppressive treatment in human T-lymphotrophic virus 1-Sjögren-associated myelopathy. 38
16966512 2006
608
AP-1-directed human T cell leukemia virus type 1 viral gene expression during monocytic differentiation. 38
16829632 2006
609
[Brain and spinal cord magnetic resonance imaging in spastic paraparesis associated to human T-lymphotropic virus]. 38
17130989 2006
610
Levels of serum chemokines discriminate clinical myelopathy associated with human T lymphotropic virus type 1 (HTLV-1)/tropical spastic paraparesis (HAM/TSP) disease from HTLV-1 carrier state. 38
16879249 2006
611
Human T-cell lymphotropic virus type 1 provirus and phylogenetic analysis in patients with mycosis fungoides and their family relatives. 38
16882177 2006
612
Reduction of human T-cell leukemia virus type 1 (HTLV-1) proviral loads in rats orally infected with HTLV-1 by reimmunization with HTLV-1-infected cells. 38
16840318 2006
613
High endemicity of human T-cell lymphotropic virus type 1 among pregnant women in peru. 38
16773029 2006
614
Flow cytometry evaluation of the T-cell receptor Vbeta repertoire among human T-cell lymphotropic virus type-1 (HTLV-1) infected individuals: effect of interferon alpha therapy in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
16545396 2006
615
Clinical and epidemiological aspects of HTLV-II infection in São Paulo, Brazil: presence of tropical spastic paraparesis/HTLV-associated myelopathy (TSP/HAM) simile diagnosis in HIV-1-co-infected subjects. 38
17119676 2006
616
Role of neuronal interferon-gamma in the development of myelopathy in rats infected with human T-cell leukemia virus type 1. 38
16816372 2006
617
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients. 38
16791359 2006
618
Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: application of best-fit logistic regression equation based on host genotype, age, and provirus load. 38
16877298 2006
619
Autoantibodies that recognize functional domains of hnRNPA1 implicate molecular mimicry in the pathogenesis of neurological disease. 38
16600502 2006
620
Reduced Foxp3 protein expression is associated with inflammatory disease during human t lymphotropic virus type 1 Infection. 38
16652285 2006
621
Human T-lymphotropic virus type-1 (HTLV-1) in Israeli patients and their family relatives and its transmission to rats. 38
16220308 2006
622
Lack of tax diversity for tropical spastic paraparesis/human T-cell lymphotropic virus type 1 (HTLV-I) associated myelopathy development in HTLV-I-infected subjects in São Paulo, Brazil. 38
16862321 2006
623
Immunostimulation by induced expression of NKG2D and its MIC ligands in HTLV-1-associated neurologic disease. 38
16568261 2006
624
Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways. 38
16652169 2006
625
Trophic factors in cerebrospinal fluid and spinal cord of patients with tropical spastic paraparesis, HIV, and Creutzfeldt-Jakob disease. 38
16545011 2006
626
Tuberculous meningoencephalomyelitis and coinfection with HTLV-I + HTLV-II: case report. 38
16622568 2006
627
Nocturnal hypertension and autonomic dysfunction due to human T-lymphotropic virus type-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
16503269 2006
628
[Cloning and transmembrane glycoprotein expression of the retrovirus HTLV-1 in mammals' cells]. 38
16699644 2006
629
Use of human antigen presenting cell gene array profiling to examine the effect of human T-cell leukemia virus type 1 Tax on primary human dendritic cells. 38
16595374 2006
630
Modulation of nuclear factor-kappaB by human T cell leukemia virus type 1 Tax protein: implications for oncogenesis and inflammation. 38
16720895 2006
631
Modulation of nuclear factor-ϰB by human T cell leukemia virus type 1 tax protein : Implications for oncogenesis and inflammation. 38
27519575 2006
632
HTLV in the Americas: challenges and perspectives. 38
16536938 2006
633
Oncolytic activity of vesicular stomatitis virus in primary adult T-cell leukemia. 38
16186807 2006
634
Modulation of T cell responses in HTLV-1 carriers and in patients with myelopathy associated with HTLV-1. 38
17119343 2006
635
Preclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemia. 38
16387851 2006
636
Genetic variability in the extracellular matrix protein as a determinant of risk for developing HTLV-I-associated neurological disease. 38
16402214 2006
637
Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis. 38
16338746 2005
638
[HTLV infection after renal transplant]. 38
16482858 2005
639
Muscle wasting induced by HTLV-1 tax-1 protein: an in vitro and in vivo study. 38
16314474 2005
640
Human T-cell lymphotropic virus type I (HTLV-I) proviral DNA viral load among asymptomatic patients and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
16258633 2005
641
The human T-cell leukemia virus type 1 (HTLV-1): new insights into the clinical aspects and molecular pathogenesis of adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/HTLV-associated myelopathy (TSP/HAM). 38
16276549 2005
642
Presence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein. 38
16285885 2005
643
A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis. 38
15961107 2005
644
Human T cell leukemia virus type I-infected patients with Hashimoto's thyroiditis and Graves' disease. 38
16076945 2005
645
HTLV-1 proviral load in peripheral blood mononuclear cells quantified in 100 HAM/TSP patients: a marker of disease progression. 38
15972218 2005
646
Tropical spastic paraparesis/human T leukemia virus type 1-associated myelopathy in HIV type 1-coinfected patients. 38
16107970 2005
647
The peripheral nervous system complications of HTLV-1 myelopathy (HAM/TSP) syndromes. 38
16170744 2005
648
[Somatosensitive and motor evoked potentials in HTLV-I associated myelopathy]. 38
16172717 2005
649
Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2. 38
16155606 2005
650
Global epidemiology of HTLV-I infection and associated diseases. 38
16155612 2005
651
Infective dermatitis and human T cell lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis in childhood and adolescence. 38
16028164 2005
652
Discrete serum protein signatures discriminate between human retrovirus-associated hematologic and neurologic disease. 38
15889159 2005
653
Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. 38
16006517 2005
654
Erectile dysfunction and HTLV-I infection: a silent problem. 38
15875060 2005
655
Human T lymphotropic virus type I (HTLV-I) proviral load in cerebrospinal fluid: a new criterion for the diagnosis of HTLV-I-associated myelopathy/tropical spastic paraparesis? 38
15871115 2005
656
Genetic markers on the HTLV-1 p12I protein sequences from Brazilian HAM/TSP patients and asymptomatic HTLV-1 carrier isolates. 38
15989464 2005
657
Infective dermatitis associated with the human T cell lymphotropic virus type I in Salvador, Bahia, Brazil. 38
15889351 2005
658
ApaI polymorphism of vitamin D receptor gene is associated with susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in HTLV-1 infected individuals. 38
15850579 2005
659
Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I-associated neuroimmunological disease. 38
15864353 2005
660
A tax on luxury: HTLV-I infection of CD4+CD25+ Tregs. 38
15864345 2005
661
Disability profile of patients with HTLV-I-associated myelopathy/tropical spastic paraparesis using the Functional Independence Measure (FIM). 38
15520834 2005
662
Secretion of the human T cell leukemia virus type I transactivator protein tax. 38
15659397 2005
663
Interferon-beta1a therapy in human T-lymphotropic virus type I-associated neurologic disease. 38
15786444 2005
664
Expression of glucose transporter 1 confers susceptibility to human T-cell leukemia virus envelope-mediated fusion. 38
15767416 2005
665
Presence of HTLV-I Tax protein in cerebrospinal fluid from HAM/TSP patients. 38
15592888 2005
666
Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals. 38
15722539 2005
667
Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway. 38
15708600 2005
668
Helminthic infection down-regulates type 1 immune responses in human T cell lymphotropic virus type 1 (HTLV-1) carriers and is more prevalent in HTLV-1 carriers than in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
15655786 2005
669
Quantitative assessment of spasticity in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
15804962 2005
670
Involvement of p38 MAPK signaling pathway in IFN-gamma and HTLV-I expression in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
15652420 2005
671
Gender influence on the progression of HTLV-I associated myelopathy/tropical spastic paraparesis. 38
15654060 2005
672
Autoimmunity and molecular mimicry in tropical spastic paraparesis/human T-lymphotropic virus-associated myelopathy. 38
15785836 2005
673
CSF-chemokines in HTLV-I-associated myelopathy: CXCL10 up-regulation and therapeutic effect of interferon-alpha. 38
15652417 2005
674
Bronchoalveolar lymphocytosis correlates with human T lymphotropic virus type I (HTLV-I) proviral DNA load in HTLV-I carriers. 38
15681503 2005
675
Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease. 38
15686595 2005
676
Backward bifurcation in a model for HTLV-I infection of CD4+ T cells. 38
15691541 2005
677
[Dermatologic lesions in patients infected with the human T-cell lymphotropic virus type 1 (HTLV-1)]. 38
15717094 2005
678
HTLV-1 induced molecular mimicry in neurological disease. 38
16323422 2005
679
Setting the stage for transformation: HTLV-1 Tax inhibition of p53 function. 38
15569630 2005
680
Retinal vasculitis caused by adult T-cell leukemia/lymphoma. 38
15692773 2005
681
Histopathological and immunohistochemical studies of infective dermatitis associated with HTLV-I. 38
15701589 2005
682
[Tropical spastic paraparesis and HTLV-I associated myelopathy in infancy. A case report and review of the literature]. 38
15625631 2004
683
Increased mRNA expression of Th1-cytokine signaling molecules in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
15572854 2004
684
Autoantibodies against heterogeneous nuclear ribonucleoprotein B1 in CSF of MS patients. 38
15497154 2004
685
Regulation of the GATA3 promoter by human T-cell lymphotropic virus type I Tax protein. 38
15486968 2004
686
Human T-cell leukemia virus type I Tax induces the expression of dendritic cell markers associated with maturation and activation. 38
15765807 2004
687
Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional activity influences the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
15465610 2004
688
Establishing phenotypic features associated with morbidity in human T-cell lymphotropic virus type 1 infection. 38
15539514 2004
689
Clinical characteristics of patients in Peru with human T cell lymphotropic virus type 1-associated tropical spastic paraparesis. 38
15472843 2004
690
Polymorphism in the interleukin-10 promoter affects both provirus load and the risk of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
15346339 2004
691
Direct evidence for a chronic CD8+-T-cell-mediated immune reaction to tax within the muscle of a human T-cell leukemia/lymphoma virus type 1-infected patient with sporadic inclusion body myositis. 38
15367598 2004
692
Chronic progressive cervical myelopathy with HTLV-I infection: Variant form of HAM/TSP? 38
15477551 2004
693
Human T cell lymphotropic virus type I (HTLV-I) p12I is dispensable for HTLV-I transmission and maintenance of infection in vivo. 38
15585100 2004
694
Immunopathogensis of HTLV-I associated neurologic disease: molecular, histopathologic, and immunologic approaches. 38
15353305 2004
695
HTLV envelopes and their receptor GLUT1, the ubiquitous glucose transporter: a new vision on HTLV infection? 38
15353351 2004
696
Elevated expression of CCL5/RANTES in adult T-cell leukemia cells: possible transactivation of the CCL5 gene by human T-cell leukemia virus type I tax. 38
15239133 2004
697
Association of a novel single nucleotide polymorphism in the human perforin gene with the outcome of HTLV-I infection in patients from northeast Iran (Mash-had). 38
15336785 2004
698
Epitope analysis of the cerebrospinal fluid IgG in HTLV-I associated myelopathy patients using phage display method. 38
15223246 2004
699
Peripheral neuropathy in HTLV-I infected individuals without tropical spastic paraparesis/HTLV-I-associated myelopathy. 38
15258793 2004
700
Spinal cord swelling in human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis: magnetic resonance indication for early anti-inflammatory treatment? 38
15262750 2004
701
HTLV-I associated myelopathy/tropical spastic paraparesis in a 7-year-old boy associated with infective dermatitis. 38
15240193 2004
702
The epidemiology and disease outcomes of human T-lymphotropic virus type II. 38
15595431 2004
703
Human T-lymphotropic virus type II and neurological disease. 38
15236397 2004
704
Molecular mimicry: cross-reactive antibodies from patients with immune-mediated neurologic disease inhibit neuronal firing. 38
15197740 2004
705
HTLV-1 provirus load in peripheral blood lymphocytes of HTLV-1 carriers is diminished by green tea drinking. 38
15245597 2004
706
HTLV-1-associated myelopathy/tropical spastic paraparesis accompanied with psoriasis. 38
15178221 2004
707
Human T cell lymphotropic virus (HTLV) type-1-specific CD8+ T cells: frequency and immunodominance hierarchy. 38
15181578 2004
708
Increased expression of human T lymphocyte virus type I (HTLV-I) Tax11-19 peptide-human histocompatibility leukocyte antigen A*201 complexes on CD4+ CD25+ T Cells detected by peptide-specific, major histocompatibility complex-restricted antibodies in patients with HTLV-I-associated neurologic disease. 38
15136590 2004
709
Extracellular matrix protein expression in cerebrospinal fluid from patients with tropical spastic paraparesis associated with HTLV-I and Creutzfeldt-Jakob disease. 38
15115246 2004
710
Serum concentration and genetic polymorphism in the 5'-untraslated region of VEGF is not associated with susceptibility to HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-I infected individuals. 38
15050452 2004
711
Immune responses to HTLV-I(ACH) during acute infection of pig-tailed macaques. 38
15157363 2004
712
Exacerbated inflammatory cellular immune response characteristics of HAM/TSP is observed in a large proportion of HTLV-I asymptomatic carriers. 38
15070424 2004
713
Increased mortality associated with HTLV-II infection in blood donors: a prospective cohort study. 38
15169553 2004
714
Human T cell lymphotropic virus type I (HTLV-I)-specific CD4+ T cells: immunodominance hierarchy and preferential infection with HTLV-I. 38
14734756 2004
715
[HTLV1 infection and pregnancy]. 38
14968050 2004
716
Decreased human T lymphotropic virus type I (HTLV-I) provirus load and alteration in T cell phenotype after interferon-alpha therapy for HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
14702150 2004
717
[Human T lymphotropic virus: from molecular epidemiology to disease]. 38
15771024 2004
718
Possible etiologies for tropical spastic paraparesis and human T lymphotropic virus I-associated myelopathy. 38
14689037 2004
719
Protein profile of tax-associated complexes. 38
14530271 2004
720
HTLV-I/II prevalence in different geographic locations. 38
14689377 2004
721
Natural course of voiding function in patients with human T-cell lymphotrophic virus type 1-associated myelopathy. 38
14675601 2004
722
Tropical spastic paraparesis in Kerala. 38
14742930 2003
723
Multiple clinical manifestation of HTLV1 infection in a single patient. 38
15040072 2003
724
Prevalence and clinical features of HTLV neurologic disease in the HTLV Outcomes Study. 38
14663047 2003
725
HTLV-1 and associated adult T-cell leukemia/lymphoma. 38
15129647 2003
726
Ocular manifestations of human T-cell lymphotropic virus type 1 infection. 38
14615649 2003
727
Human T-lymphotropic virus type 1 (HTLV-1): persistence and immune control. 38
14686486 2003
728
A C77G point mutation in CD45 exon 4, which is associated with the development of multiple sclerosis and increased susceptibility to HIV-1 infection, is undetectable in Japanese population. 38
14641523 2003
729
Human T lymphotropic virus type 1 in a seronegative B chronic lymphocytic leukemia patient. 38
14615889 2003
730
Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis. 38
13129766 2003
731
Neurological manifestations in HTLV-I-infected blood donors. 38
12972388 2003
732
The genetic background as a determinant of human T-cell leukemia virus type 1 proviral load. 38
12943677 2003
733
High circulating frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4+ T cells in patients with HTLV-1-associated neurological disease. 38
12915584 2003
734
A possible case of myelopathy/tropical spastic paraparesis in an Argentinian woman with human T lymphocyte virus type II. 38
12884173 2003
735
Osteoporosis in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
14499352 2003
736
Interferon-alpha significantly reduces cerebrospinal fluid CD4 cell subsets in HAM/TSP. 38
12965269 2003
737
Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades. 38
12910251 2003
738
Neuropsychological assessment in HTLV-1 infection: a comparative study among TSP/HAM, asymptomatic carriers, and healthy controls. 38
12876239 2003
739
Sequence and phylogenetic analysis of human T cell lymphotropic virus type 1 from Tumaco, Colombia. 38
12973531 2003
740
Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers. 38
12560226 2003
741
Acute human T-lymphotropic virus type 1-associated myelopathy: a clinicopathologic study. 38
12810493 2003
742
Hospital admissions for human T-cell lymphotropic virus type-1 (HTLV-1) associated diseases in Dominica. 38
12840124 2003
743
Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax. 38
12670929 2003
744
Transduction of dominant negative ATF-1 suppresses the pX gene expression in joint fibroblastic cells derived from HTLV-I transgenic rats. 38
12782019 2003
745
Seroindeterminate HTLV-1 prevalence and characteristics in blood donors in Taiwan. 38
12774934 2003
746
Dermatologic lesions in asymptomatic blood donors seropositive for human T cell lymphotropic virus type-1. 38
12812346 2003
747
TIMPs and MMPs expression in CSF from patients with TSP/HAM. 38
12697269 2003
748
IgG in brain correlates with clinicopathological damage in HTLV-1 associated neurologic disease. 38
12707436 2003
749
Human T-cell lymphotropic virus type I and neurological diseases. 38
12707853 2003
750
Different cytokine production in tax-expressing cells between patients with human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis and asymptomatic HTLV-I carriers. 38
12660926 2003
751
A cluster of human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Jujuy, Argentina. 38
12640204 2003
752
P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway. 38
12655090 2003
753
Degenerate specificity of HTLV-1-specific CD8+ T cells during viral replication in patients with HTLV-1-associated myelopathy (HAM/TSP). 38
12480698 2003
754
Human T-cell leukemia virus type I infection in various recipients of transplants from the same donor. 38
12698089 2003
755
Axonal damage: a key predictor of outcome in human CNS diseases. 38
12566274 2003
756
Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells. 38
12708749 2003
757
Pathological and virological assessment of acute HTLV-I-associated myelopathy complicated with encephalopathy and systemic inflammation. 38
12614936 2003
758
Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration. 38
12706085 2003
759
Human T-cell lymphotropic virus type I (HTLV-I)-related clinical and laboratory findings for HTLV-I-infected blood donors. 38
12626894 2003
760
Usefulness of proviral load measurement for monitoring of disease activity in individual patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
12587066 2003
761
Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in seronegative tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) patients. 38
12573502 2003
762
Dermatological findings of human T lymphotropic virus type 1 (HTLV-I)-associated myelopathy/tropical spastic paraparesis. 38
12567310 2003
763
MRI contributes to the differentiation between MS and HTLV-I associated myelopathy in British Columbian coastal natives. 38
12619783 2003
764
The clinical and pathological features of peripheral neuropathy accompanied with HTLV-I associated myelopathy. 38
12480079 2003
765
Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. 38
12477694 2003
766
Global epidemic of human T-cell lymphotrophic virus type-I (HTLV-I): an update. 38
14510286 2003
767
Activation of HTLV-I long terminal repeat by apoptosis inducing agents: mechanism and implications for HTLV-I pathogenicity (review). 38
12469209 2003
768
Mitral valve re-replacement for impaired bioprosthesis after 19 years in a patient undergoing steroid treatment. 38
12578334 2003
769
Immunopathogenesis of human T cell lymphotropic virus type I-associated neurologic disease. 38
12424696 2002
770
Association of primate T-cell lymphotropic virus infection of pig-tailed macaques with high mortality. 38
12504576 2002
771
Cross-reactivity between immunodominant human T lymphotropic virus type I tax and neurons: implications for molecular mimicry. 38
12404172 2002
772
Detection of myelin basic protein in cerebrospinal fluid. 38
12465458 2002
773
Pathogenesis and treatment of human T-cell lymphotropic virus Type I-associated myelopathy. 38
19810922 2002
774
The ultrastructure of bladder lamina propria nerves in healthy subjects and patients with detrusor hyperreflexia. 38
12394704 2002
775
Detection of myelin basic protein in cerebrospinal fluid and serum from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
12564844 2002
776
Polygenic control of human T lymphotropic virus type I (HTLV-I) provirus load and the risk of HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
12232833 2002
777
Pathological mechanisms of human T-cell lymphotropic virus type I-associated myelopathy (HAM/TSP). 38
12402162 2002
778
Neuropathology of two Brazilian autopsied cases of tropical spastic paraparesis / HTLV-I associated myelopathy (TSP/HAM) of long evolution. 38
12244385 2002
779
Increased IL-13 but not IL-5 production by CD4-positive T cells and CD8-positive T cells in multiple sclerosis during relapse phase. 38
12163193 2002
780
[Infection and disease caused by the human T cell lymphotropic viruses type I and II in Brazil]. 38
12621671 2002
781
Urodynamic alterations in patients with HTLV-1 infection. 38
15748372 2002
782
Retroviral proteins that target the major histocompatibility complex class I. 38
12297331 2002
783
[Retrovirus, mycotoxins, immunosuppression and neurodegeneration]. 38
12389174 2002
784
Frequency of p12K and p12R alleles of HTLV Type 1 in HAM/TSP patients and in asymptomatic HTLV type 1 carriers. 38
12230932 2002
785
Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors. 38
12236581 2002
786
Ocular lesions in 200 patients infected by the human T-cell lymphotropic virus type 1 in martinique (French West Indies). 38
12140025 2002
787
Efficient transfer of HTLV-1 tax gene in various primary and immortalized cells using a flap lentiviral vector. 38
12176150 2002
788
Juvenile human T lymphotropic virus type 1-associated myelopathy. 38
12087528 2002
789
[Human T-cell lymphotropic virus type 1(HTLV-1)-associated myelopathy]. 38
12170334 2002
790
Transcription profile of cells infected with human T-cell leukemia virus type I compared with activated lymphocytes. 38
12068005 2002
791
Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy. 38
12044984 2002
792
Infectious myelopathies. 38
12524558 2002
793
Phenotypic study of peripheral blood leucocytes in HTLV-I-infected individuals from Minas Gerais, Brazil. 38
12028566 2002
794
Inhibition of the tax-dependent human T-lymphotropic virus type I replication in persistently infected cells by the fluoroquinolone derivative k-37. 38
12021397 2002
795
Human T-lymphotropic virus type I and II infections in First Nations alcohol and drug treatment centres in British Columbia, Canada, 1992-2000. 38
12078968 2002
796
High frequencies of Th1-type CD4(+) T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. 38
11964301 2002
797
Autoimmunity due to molecular mimicry as a cause of neurological disease. 38
11984596 2002
798
Human T cell lymphotropic virus type 1-associated myelopathy in São Paulo, Brazil. Epidemiologic and clinical features of a university hospital cohort. 38
12006779 2002
799
Inhibition of human T-lymphotropic virus type I gene expression by the Streptomyces-derived substance EM2487. 38
12448690 2002
800
Up-regulation of interleukin-12 receptor expression in peripheral blood mononuclear cells of patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
11959151 2002
801
Identification of human T-lymphotropic virus type I (HTLV-I) subtypes using restricted fragment length polymorphism in a cohort of asymptomatic carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis from São Paulo, Brazil. 38
12048560 2002
802
Quantitation of HTLV-I proviral load by a TaqMan real-time PCR assay. 38
11879691 2002
803
Neuropathology of human and experimental TSP/HAM: a critical review. 38
12094559 2002
804
Genetic characterization and phylogeny of human T-cell lymphotropic virus type I from Chile. 38
11900846 2002
805
Human T cell leukemia virus type-I Tax activates human macrophage inflammatory protein-3 alpha/CCL20 gene transcription via the NF-kappa B pathway. 38
11809734 2002
806
Selected cytotoxic T lymphocytes with high specificity for HTLV-I in cerebrospinal fluid from a HAM/TSP patient. 38
11847592 2002
807
Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness. 38
11830485 2002
808
Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation. 38
11807819 2002
809
Correlation of human T-cell lymphotropic virus type 1 (HTLV-1) mRNA with proviral DNA load, virus-specific CD8(+) T cells, and disease severity in HTLV-1-associated myelopathy (HAM/TSP). 38
11756157 2002
810
[The immune response to human T-cell lymphotropic virus type 1]. 38
12854182 2002
811
IRF-4 activities in HTLV-I-induced T cell leukemogenesis. 38
11846984 2002
812
Association of CD40 ligand expression on HTLV-I-infected T cells and maturation of dendritic cells. 38
11902332 2001
813
Increased HTLV-I proviral load and preferential expansion of HTLV-I Tax-specific CD8+ T cells in cerebrospinal fluid from patients with HAM/TSP. 38
11761481 2001
814
Rat CRM1 is responsible for the poor activity of human T-cell leukemia virus type 1 Rex protein in rat cells. 38
11689633 2001
815
IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients. 38
11717409 2001
816
[Cases of tropical spastic paraparesis in Spain]. 38
11742627 2001
817
Dysautonomia in human T-cell lymphotrophic virus type I-associated myelopathy/tropical spastic paraparesis. 38
11706978 2001
818
Activation of HTLV-I long terminal repeat by stress-inducing agents and protection of HTLV-I-infected T-cells from apoptosis by the viral tax protein. 38
11697893 2001
819
HTLV-I associated myelopathy/tropical spastic paraparesis with pseudohypothyroidism. 38
11591873 2001
820
Tc1/Tc2 and Th1/Th2 balance in Asian and Western types of multiple sclerosis, HTLV-I-associated myelopathy/tropical spastic paraparesis and hyperIgEaemic myelitis. 38
11585633 2001
821
In vitro spontaneous lymphoproliferation in patients with human T-cell lymphotropic virus type I-associated neurologic disease: predominant expansion of CD8+ T cells. 38
11520801 2001
822
CD8(+) T cells are an in vivo reservoir for human T-cell lymphotropic virus type I. 38
11535522 2001
823
HTLV-1 and its neurological complications. 38
12803668 2001
824
High production of interferon gamma but not interleukin-2 by human T-lymphotropic virus type I-infected peripheral blood mononuclear cells. 38
11468172 2001
825
Diagnosis of HAM/TSP based on CSF proviral HTLV-I DNA and HTLV-I antibody index. 38
11524492 2001
826
[HTLV-I seronegative idiopathic progressive spastic paraparesis: clinical and neurophysiological study of the sensory features]. 38
11552441 2001
827
HLA-A*26, HLA-B*4002, HLA-B*4006, and HLA-B*4801 alleles predispose to adult T cell leukemia: the limited recognition of HTLV type 1 tax peptide anchor motifs and epitopes to generate anti-HTLV type 1 tax CD8(+) cytotoxic T lymphocytes. 38
11485622 2001
828
Cytotoxic T-cell abundance and virus load in human immunodeficiency virus type 1 and human T-cell leukaemia virus type 1. 38
11410146 2001
829
Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B. 38
11325603 2001
830
Molecular biology and pathogenesis of the human T-cell leukaemia/lymphotropic virus Type-1 (HTLV-1). 38
11488989 2001
831
Immunopathogenesis of human T cell lymphotropic virus type I-associated myelopathy. 38
11371764 2001
832
HTLV-I negative tropical spastic paraparesis: a scientific challenge. 38
11400047 2001
833
Quantification of HTLV type I and HIV type I DNA load in coinfected patients: HIV type 1 infection does not alter HTLV type I proviral amount in the peripheral blood compartment. 38
11429121 2001
834
HTLV-I proviral load correlates with progression of motor disability in HAM/TSP: analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years. 38
11517397 2001
835
Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state. 38
11342446 2001
836
Cell-free entry of human T-cell leukemia virus type 1 to mouse cells. 38
11346463 2001
837
[Spastic paraparesias by HTLV-1: early identification of a new case. Review of the Spanish casuistics]. 38
11412711 2001
838
New corneal findings in human T-cell lymphotrophic virus type 1 infection. 38
11239862 2001
839
[Tropical spastic paraparesis due to HTLV-1. A case report]. 38
11426415 2001
840
Clinical and physiological significance of abnormally prolonged central motor conduction time in HAM/TSP. 38
11266689 2001
841
A description of human T-lymphotropic virus type I-related chronic interstitial keratitis in 20 patients. 38
11239861 2001
842
High signal in the spinal cord on T2-weighted images in rapidly progressive tropical spastic paraparesis. 38
11305756 2001
843
Human T cell leukemia virus Type I (HTLV-I) infection induces greater expansions of CD8 T lymphocytes in persons with HTLV-I-associated myelopathy/tropical spastic paraparesis than in asymptomatic carriers. 38
11237801 2001
844
Intrafamilial transmission and risk assessment of HTLV-I among blood donors in southern Taiwan. 38
11486644 2001
845
Existence of escape mutant in HTLV-I tax during the development of adult T-cell leukemia. 38
11159527 2001
846
Increased activated human T cell lymphotropic virus type I (HTLV-I) Tax11-19-specific memory and effector CD8+ cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis: correlation with HTLV-I provirus load. 38
11120926 2001
847
Tropical spastic paraparesis. 38
11928898 2001
848
Tropical spastic paraparesis: an old disease with a new name. 38
11176945 2001
849
HTLV-1-associated myelopathy/tropical spastic paraparesis with pseudohypoparathyroidism. 38
11148245 2001
850
IL-2 independent transformation of a unique human T cell line, TY8-3, and its subclones by HTLV-I and -II. 38
11149427 2001
851
Multiple viral strategies of HTLV-1 for dysregulation of cell growth control. 38
11244044 2001
852
Immunopathogenesis of HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
11209967 2000
853
HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with amyotrophic lateral sclerosis-like manifestations. 38
11175327 2000
854
The pathogenesis of tropical spastic paraparesis/human T-cell leukemia type I-associated myelopathy. 38
11105090 2000
855
Human T-cell lymphotropic virus testing of blood donors in Norway: a cost-effect model. 38
11101551 2000
856
Phylogenetic subgroups of human T cell lymphotropic virus (HTLV) type I in the tax gene and their association with different risks for HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
11010842 2000
857
Increased HTLV type 1 tax specific CD8+ cells in HTLV type 1-asociated myelopathy/tropical spastic paraparesis: correlation with HTLV type 1 proviral load. 38
11080814 2000
858
Hypoxanthine-guanine phosphoribosyltransferase reporter gene mutation for analysis of in vivo clonal amplification in patients with HTLV type 1-associated Myelopathy/Tropical spastic paraparesis. 38
11080821 2000
859
How does interleukin 15 contribute to the pathogenesis of HTLV type 1-associated myelopathy/tropical spastic paraparesis? 38
11080816 2000
860
Activation and regulation of interferon regulatory factor 4 in HTLV type 1-infected T lymphocytes. 38
11080800 2000
861
In vitro cellular tropism of human T cell leukemia virus type 2. 38
11080807 2000
862
Common human T cell leukemia virus type 1 (HTLV-1) integration sites in cerebrospinal fluid and blood lymphocytes of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis indicate that HTLV-1 crosses the blood-brain barrier via clonal HTLV-1-infected cells. 38
10979898 2000
863
Histopathological analysis of four autopsy cases of HTLV-I-associated myelopathy/tropical spastic paraparesis: inflammatory changes occur simultaneously in the entire central nervous system. 38
10965793 2000
864
Human T-cell leukemia virus type I tax activates transcription of the human monocyte chemoattractant protein-1 gene through two nuclear factor-kappaB sites. 38
10987310 2000
865
HTLV-I-associated myelopathy. 38
11037191 2000
866
The immune response to HTLV-I. 38
10899027 2000
867
Flow cytometric differentiation of Asian and Western types of multiple sclerosis, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and hyperIgEaemic myelitis by analyses of memory CD4 positive T cell subsets and NK cell subsets. 38
10967179 2000
868
Comparative molecular analysis of HTLV-I proviral DNA in HTLV-I infected members of a family with a discordant HTLV-I-associated myelopathy in monozygotic twins. 38
10951551 2000
869
Overexpression of p21(waf1) in human T-cell lymphotropic virus type 1-infected cells and its association with cyclin A/cdk2. 38
10906181 2000
870
Interactions between brain endothelial cells and human T-cell leukemia virus type 1-infected lymphocytes: mechanisms of viral entry into the central nervous system. 38
10846084 2000
871
Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha. 38
10864655 2000
872
[Epidemiology, origin and genetic diversity of HTLV-1 retrovirus and STLV-1 simian affiliated retrovirus]. 38
11030050 2000
873
[Potentially treatable subacute forms of infection due to the HTLV-1]. 38
10948579 2000
874
Spinocerebellar syndrome in patients infected with human T-lymphotropic virus types I and II (HTLV-I/HTLV-II): report of 3 cases from Panama. 38
10877159 2000
875
Axonal damage revealed by accumulation of beta-amyloid precursor protein in HTLV-I-associated myelopathy. 38
10930590 2000
876
Central nervous system activation of the indoleamine-2,3-dioxygenase pathway in human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. 38
10837188 2000
877
[Tropical spastic paraparesis and mixed infection due to Treponema pallidum and HTLV-I]. 38
10935266 2000
878
[Increased activity of metalloproteinases and their inhibitors in cerebrospinal fluid of patients with tropical spastic paraparesis]. 38
11016056 2000
879
[Human T-lymphotropic virus type I (HTLV-I): risk of transmission with transfusion]. 38
10901796 2000
880
Human T-lymphocyte virus type I (HTLV-I)-induced myeloneuropathy in rats: oligodendrocytes undergo apoptosis in the presence of HTLV-I. 38
11028810 2000
881
Human T-lymphotropic virus type 1 infection. 38
10942623 2000
882
Serum S100B levels in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
10822451 2000
883
Frequent reversible membrane damage in peripheral blood B cells in human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). 38
10792381 2000
884
An altered peptide ligand antagonizes antigen-specific T cells of patients with human T lymphotropic virus type I-associated neurological disease. 38
10799878 2000
885
Chimeric matrix proteins encoded by defective proviruses with large internal deletions in human T-cell leukemia virus type 1-infected humans. 38
10756004 2000
886
Human polyomavirus JCV and expression of myelin genes. 38
10871794 2000
887
Hyperprolactinemia in optico-spinal multiple sclerosis. 38
10801143 2000
888
Non-HIV retroviral associations with rheumatic disease. 38
11123053 2000
889
Transmission of human T-cell lymphotropic virus type 1 tax to rabbits by tax-only-positive human cells. 38
10702504 2000
890
Human T-cell lymphotropic virus-I in Latin America. 38
10738680 2000
891
[Chronological analyses of neuropathological and molecular biological changes in affected spinal cord of HTLV-I-infected rat (HAM rat disease)]. 38
10791252 2000
892
Evidence for the chronic in vivo production of human T cell leukemia virus type I Rof and Tof proteins from cytotoxic T lymphocytes directed against viral peptides. 38
10662802 2000
893
Global epidemic of human T-cell lymphotropic virus type-I (HTLV-I). 38
10645850 2000
894
Decreased GATA3 mRNA expression in human T-cell lymphotropic virus type 1 (HTLV-1) infection. 38
10826901 2000
895
Virus inactivation in a proportion of human T-cell leukaemia virus type I-infected T-cell clones arises through naturally occurring mutations. 38
10640546 2000
896
[HTLV-I--associated myelopathy/tropical spastic paraparesis (HAM/TSP)]. 38
11269197 2000
897
Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemia. 38
10702386 2000
898
HTLV-I specific IFN-gamma+ CD8+ lymphocytes correlate with the proviral load in peripheral blood of infected individuals. 38
10636490 2000
899
Human T lymphotropic virus I in Indonesia. Very low seroprevalence in the Jakarta area: antibodies in healthy blood donors and in various nonhematological diseases. 38
10971124 2000
900
Optic-spinal form of multiple sclerosis and immune-mediated myelopathy in Japan. 38
11128610 2000
901
CD44 splice variant involvement in the chronic inflammatory disease of the spinal cord: HAM/TSP. 38
10626660 2000
902
[Tropical spastic paraparesis and mixed infection due to Treponema pallidum and HTLV-1]. 38
10652773 1999
903
Effect of lamivudine on human T-cell leukemia virus type 1 (HTLV-1) DNA copy number, T-cell phenotype, and anti-tax cytotoxic T-cell frequency in patients with HTLV-1-associated myelopathy. 38
10559346 1999
904
Transcriptional up-regulation of the cyclin D2 gene and acquisition of new cyclin-dependent kinase partners in human T-cell leukemia virus type 1-infected cells. 38
10559304 1999
905
Sicca syndrome and HTLV-I-associated myelopathy/tropical spastic paraparesis. 38
10672880 1999
906
[Cerebellar syndrome and peripheral neuropathy as manifestations of infection by HTLV-1 human T-cell lymphotropic virus]. 38
10637843 1999
907
Quantitative proviral DNA and antibody levels in the natural history of HTLV-I infection. 38
10515807 1999
908
Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor. 38
10491011 1999
909
An inverse correlation of HTLV-I viral load in CSF and intrathecal synthesis of HTLV-I antibodies in TSP/HAM. 38
10522895 1999
910
Nucleotide sequence analysis of human T-cell lymphotropic virus type I pX and LTR regions from patients with sicca syndrome. 38
10459164 1999
911
Monocyte-driven activation-induced apoptotic cell death of human T-lymphotropic virus type I-infected T cells. 38
10490992 1999
912
HTLV-I/II seroindeterminate Western blot reactivity in a cohort of patients with neurological disease. 38
10438355 1999
913
[Tropical spastic paraparesis/HTLV-I associated myelopathy. Report of 2 cases diagnosed in Cuiabá, Mato Grosso, Brazil]. 38
10751927 1999
914