HCVS
MCID: HMN038
MIFTS: 21

Human Coronavirus Sensitivity (HCVS)

Categories: Infectious diseases
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Aliases & Classifications for Human Coronavirus Sensitivity

MalaCards integrated aliases for Human Coronavirus Sensitivity:

Name: Human Coronavirus Sensitivity 57
Coronavirus 229e Susceptibility 57
Hcvs 57
Cvs 57

Characteristics:


Inheritance:

Autosomal dominant 57

Classifications:



External Ids:

OMIM® 57 122460
MedGen 40 C1852539

Summaries for Human Coronavirus Sensitivity

MalaCards based summary: Human Coronavirus Sensitivity, also known as coronavirus 229e susceptibility, is related to cyclic vomiting syndrome and trisomy 2 mosaicism. An important gene associated with Human Coronavirus Sensitivity is HCVS (Human Coronavirus Sensitivity). Affiliated tissues include temporal lobe, kidney and liver, and related phenotype is susceptibility to coronavirus 229e.

More information from OMIM: 122460

Related Diseases for Human Coronavirus Sensitivity

Diseases in the Human Coronavirus Sensitivity family:

Coronavirus Infectious Disease

Diseases related to Human Coronavirus Sensitivity via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
# Related Disease Score Top Affiliating Genes
1 cyclic vomiting syndrome 11.7
2 trisomy 2 mosaicism 11.1
3 spinal muscular atrophy 11.0
4 neu-laxova syndrome 1 11.0
5 rabies 10.5
6 down syndrome 10.4
7 turner syndrome 10.3
8 orofaciodigital syndrome viii 10.2
9 adult syndrome 10.2
10 47 xxx syndrome 10.1
11 chromosome 16 trisomy 10.1
12 migraine with or without aura 1 10.0
13 patau syndrome 10.0
14 vascular disease 10.0
15 muscular atrophy 10.0
16 49, xxxxy syndrome 10.0
17 reversible cerebral vasoconstriction syndrome 10.0
18 mosaic trisomy 3 10.0
19 pallister-killian syndrome 9.9
20 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 9.9
21 intracranial berry aneurysm 9.9
22 omphalocele 9.9
23 hypogonadotropic hypogonadism 9.9
24 thalassemia 9.9
25 familial hyperlipidemia 9.9
26 muscular dystrophy 9.9
27 48,xyyy 9.9
28 chromosome 6q deletion 9.9
29 mosaic trisomy 13 9.9
30 tetraploidy 9.9
31 triploidy 9.9
32 autosomal trisomy 9.9
33 mosaic monosomy x 9.9
34 hypoglossia-hypodactylia 9.8
35 amyotrophic lateral sclerosis 1 9.8
36 cone-rod dystrophy 2 9.8
37 sorsby fundus dystrophy 9.8
38 hair whorl 9.8
39 chromosome 18p deletion syndrome 9.8
40 poland syndrome 9.8
41 prader-willi syndrome 9.8
42 prostate cancer 9.8
43 neural tube defects 9.8
44 thrombophilia due to thrombin defect 9.8
45 anus, imperforate 9.8
46 constricting bands, congenital 9.8
47 cystic fibrosis 9.8
48 gastroschisis 9.8
49 jejunal atresia 9.8
50 spinal muscular atrophy, type i 9.8

Graphical network of the top 20 diseases related to Human Coronavirus Sensitivity:



Diseases related to Human Coronavirus Sensitivity

Symptoms & Phenotypes for Human Coronavirus Sensitivity

Human phenotypes related to Human Coronavirus Sensitivity:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 susceptibility to coronavirus 229e 30 HP:0005396

Symptoms via clinical synopsis from OMIM®:

57 (Updated 08-Dec-2022)
Immunology:
susceptibility to coronavirus 229e

Clinical features from OMIM®:

122460 (Updated 08-Dec-2022)

Drugs & Therapeutics for Human Coronavirus Sensitivity

Search Clinical Trials, NIH Clinical Center for Human Coronavirus Sensitivity

Genetic Tests for Human Coronavirus Sensitivity

Anatomical Context for Human Coronavirus Sensitivity

Organs/tissues related to Human Coronavirus Sensitivity:

MalaCards : Temporal Lobe, Kidney, Liver, Pituitary, Bone

Publications for Human Coronavirus Sensitivity

Articles related to Human Coronavirus Sensitivity:

(show top 50) (show all 91)
# Title Authors PMID Year
1
Coronavirus 229E susceptibility in man-mouse hybrids is located on human chromosome 15. 62 57
6285532 1982
2
Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance. 62
35242360 2022
3
Two novel SARS-CoV-2 surrogate virus neutralization assays are suitable for assessing successful immunization with mRNA-1273. 62
34563583 2022
4
Divergent Anatomical Correlates and Functional Network Connectivity Patterns in Temporal Lobe Epilepsy with and Without Depression. 62
33973138 2021
5
Cooling efficiency of vests with different cooling concepts over 8-hour trials. 62
33222661 2021
6
Survivors Achieving Stable Housing: Implementation, Challenges, and Lessons Learned. 62
33479750 2021
7
Global stability of age-of-infection multiscale HCV model with therapy. 62
33892540 2021
8
Direct antivirals and cognitive impairment in hepatitis C: a clinical-neurophysiologic study. 62
32910431 2020
9
Cognitive/Functional Measures Predict Alzheimer's Disease, Dependent on Hippocampal Volume. 62
30668830 2020
10
Measuring intradialyser transmembrane and hydrostatic pressures: pitfalls and relevance in haemodialysis and haemodiafiltration. 62
32905251 2020
11
Clinical utility of structural connectomics in predicting memory in temporal lobe epilepsy. 62
32358221 2020
12
A systematic review on high conservation value assessment (HCVs): Challenges and framework for future research on conservation strategy. 62
31884271 2020
13
High resolution vehicular PM10 emissions over megacity Delhi: Relative contributions of exhaust and non-exhaust sources. 62
31683208 2020
14
Healthcare trajectory of children with rare bone disease attending pediatric emergency departments. 62
31900214 2020
15
Direct-acting antiviral therapy slows kidney function decline in patients with Hepatitis C virus infection and chronic kidney disease. 62
31337501 2020
16
A comprehensive comparison and analysis of soil screening values derived and used in China and the UK. 62
31735398 2020
17
An efficient utilization of high chromium vanadium slag: Extraction of vanadium based on manganese carbonate roasting and detoxification processing of chromium-containing tailings. 62
31202069 2019
18
Exploring the relationship of hyaluronic acid molecular weight and active targeting efficiency for designing hyaluronic acid-modified nanoparticles. 62
32104479 2019
19
Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features. 62
31182749 2019
20
Hippocampal shape alterations in healthy young women with familial risk for unipolar depression. 62
29367060 2018
21
Assessment of GHG mitigation and CDM technology in urban transport sector of Chandigarh, India. 62
29039038 2018
22
Patient's behaviors and missed opportunities for vaccination against seasonal epidemic influenza and evaluation of their impact on patient's influenza vaccine uptake. 62
29565990 2018
23
Renal function affects hippocampal volume and cognition: The role of vascular burden and amyloid deposition. 62
28224692 2017
24
Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus. 62
28864074 2017
25
Late-Life Depression, Hippocampal Volumes, and Hypothalamic-Pituitary-Adrenal Axis Regulation: A Systematic Review and Meta-analysis. 62
28318491 2017
26
Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems. 62
28322919 2017
27
Assessment of a Novel Automatic Real-Time PCR Assay on the Cobas 4800 Analyzer as a Screening Platform for Hepatitis C Virus Genotyping in Clinical Practice: Comparison with Massive Sequencing. 62
27927921 2017
28
The epithelial-mesenchymal transition (EMT) is regulated by oncoviruses in cancer. 62
27279361 2016
29
Enhancement of the Replication of Hepatitis C Virus Replicons of Genotypes 1 to 4 by Manipulation of CpG and UpA Dinucleotide Frequencies and Use of Cell Lines Expressing SECL14L2 for Antiviral Resistance Testing. 62
26953209 2016
30
The human hippocampus is not sexually-dimorphic: Meta-analysis of structural MRI volumes. 62
26334947 2016
31
[The efficiency of antiviral therapy in patients with chronic -hepatitis C infected with hepatitis C virus recombinants]. 62
27489903 2016
32
Direct-acting Antiviral Agents Resistance-associated Polymorphisms in Chinese Treatment-naïve Patients Infected with Genotype 1b Hepatitis C Virus. 62
26415801 2015
33
Taking high conservation value from forests to freshwaters. 62
25948151 2015
34
Hypercellularity Components of Glioblastoma Identified by High b-Value Diffusion-Weighted Imaging. 62
26104935 2015
35
Characterization of hepatitis C virus intergenotypic recombinant strains and associated virological response to sofosbuvir/ribavirin. 62
25099344 2015
36
Decreased right hippocampal volumes and neuroprogression markers in adolescents with bipolar disorder. 62
25925781 2015
37
Robustness of automated hippocampal volumetry across magnetic resonance field strengths and repeat images. 62
24985688 2014
38
Hypoxia-inducible factor 1 and its role in viral carcinogenesis. 62
24698149 2014
39
Genetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systems. 62
24625789 2014
40
A small-molecule inhibitor of hepatitis C virus infectivity. 62
24165192 2014
41
Vehicular emission inventory of criteria pollutants in Delhi. 62
23741649 2013
42
The association of coffee intake with liver cancer incidence and chronic liver disease mortality in male smokers. 62
23880821 2013
43
MR Volumetry of Hippocampus in Normal Adult Malay of Age 50 Years Old and Above. 62
24043993 2013
44
Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI. 62
22264648 2012
45
Two methods of heterokaryon formation to discover HCV restriction factors. 62
22825033 2012
46
Hippocampal volume in children with temporal lobe epilepsy compared to healthy children: a magnetic resonance imaging study. 62
22406776 2012
47
Prevalence and risk factors of asymptomatic hepatitis C virus infection in bangladesh. 62
25755305 2011
48
Genetic variability and diversity of intracellular genome-length hepatitis C virus RNA in long-term cell culture. 62
19082684 2009
49
HCV genotype 1b chimeric replicon with NS5B of JFH-1 exhibited resistance to cyclosporine A. 62
19779801 2009
50
[Replication of hepatitis C virus genome]. 62
19374197 2008

Variations for Human Coronavirus Sensitivity

Expression for Human Coronavirus Sensitivity

Search GEO for disease gene expression data for Human Coronavirus Sensitivity.

Pathways for Human Coronavirus Sensitivity

GO Terms for Human Coronavirus Sensitivity

Sources for Human Coronavirus Sensitivity

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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