HME
MCID: HMN001
MIFTS: 26

Human Monocytic Ehrlichiosis (HME)

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Human Monocytic Ehrlichiosis

MalaCards integrated aliases for Human Monocytic Ehrlichiosis:

Name: Human Monocytic Ehrlichiosis 12 76 53 55 15
Human Ehrlichial Infection, Human Monocytic Type 53
Ehrlichiosis Chafeensis 12
Hme 53

Classifications:



External Ids:

Disease Ontology 12 DOID:0050026

Summaries for Human Monocytic Ehrlichiosis

Disease Ontology : 12 An ehrlichiosis that results in infection located in monocyte or located in macrophage, has material basis in Ehrlichia chaffeensis, which is transmitted by black-legged tick (Ixodes scapularis), transmitted by western black-legged tick (Ixodes pacificus) or transmitted by castor bean tick (Ixodes ricinus). The infection has symptom headache, has symptom muscle aches, has symptom fatigue, has symptom fever and has symptom rash.

MalaCards based summary : Human Monocytic Ehrlichiosis, also known as human ehrlichial infection, human monocytic type, is related to hemimegalencephaly and ehrlichiosis. An important gene associated with Human Monocytic Ehrlichiosis is DNASE1L1 (Deoxyribonuclease 1 Like 1), and among its related pathways/superpathways is Th1 Differentiation Pathway. Affiliated tissues include monocytes, testes and lymph node.

Wikipedia : 76 Human monocytotropic ehrlichiosis (HME) is a form of ehrlichiosis associated with Ehrlichia chaffeensis.... more...

Related Diseases for Human Monocytic Ehrlichiosis

Graphical network of the top 20 diseases related to Human Monocytic Ehrlichiosis:



Diseases related to Human Monocytic Ehrlichiosis

Symptoms & Phenotypes for Human Monocytic Ehrlichiosis

Drugs & Therapeutics for Human Monocytic Ehrlichiosis

Search Clinical Trials , NIH Clinical Center for Human Monocytic Ehrlichiosis

Genetic Tests for Human Monocytic Ehrlichiosis

Anatomical Context for Human Monocytic Ehrlichiosis

MalaCards organs/tissues related to Human Monocytic Ehrlichiosis:

41
Monocytes, Testes, Lymph Node

Publications for Human Monocytic Ehrlichiosis

Articles related to Human Monocytic Ehrlichiosis:

(show all 34)
# Title Authors Year
1
Large-scale health disparities associated with Lyme disease and human monocytic ehrlichiosis in the United States, 2007-2013. ( 30261027 )
2018
2
Sudden sensorineural hearing loss in human monocytic ehrlichiosis. ( 28846788 )
2017
3
Human monocytic ehrlichiosis complicated by hemophagocytic lymphohistiocytosis and multi-organ dysfunction syndrome. ( 27575459 )
2016
4
Severe human monocytic ehrlichiosis presenting with altered mental status and seizures. ( 27758794 )
2016
5
Successful Treatment of Human Monocytic Ehrlichiosis with Rifampin. ( 26918212 )
2016
6
The perils of country life: human monocytic ehrlichiosis. ( 25912197 )
2015
7
Bayesian spatio-temporal analysis and geospatial risk factors of human monocytic ehrlichiosis. ( 24992684 )
2014
8
A case of human monocytic ehrlichiosis in Serbia. ( 24684037 )
2014
9
Macrophage activation syndrome secondary to human monocytic ehrlichiosis. ( 25332563 )
2014
10
Multiorgan failure related to human monocytic ehrlichiosis. ( 23704428 )
2013
11
Ehrlichia chaffeensis human monocytic ehrlichiosis with pancytopenia. ( 22497260 )
2012
12
Fatal human monocytic ehrlichiosis: a case study. ( 21279705 )
2011
13
Results from a mathematical model for human monocytic ehrlichiosis. ( 20584161 )
2009
14
Diminished hematopoietic activity associated with alterations in innate and adaptive immunity in a mouse model of human monocytic ehrlichiosis. ( 19451243 )
2009
15
Current management of human granulocytic anaplasmosis, human monocytic ehrlichiosis and Ehrlichia ewingii ehrlichiosis. ( 19681699 )
2009
16
Acute infection with human monocytic ehrlichiosis: the tip of the iceberg? ( 18364633 )
2008
17
Human monocytic ehrlichiosis in children. ( 17529862 )
2007
18
Human monocytic ehrlichiosis and human granulocytic anaplasmosis in the United States, 2001-2002. ( 17114690 )
2006
19
Lymph node hemophagocytosis in rickettsial diseases: a pathogenetic role for CD8 T lymphocytes in human monocytic ehrlichiosis (HME)? ( 16859547 )
2006
20
Human monocytic ehrlichiosis in a renal transplant patient. ( 16857619 )
2006
21
Human monocytic ehrlichiosis. ( 15536115 )
2004
22
Ehrlichia chaffeensis infections among HIV-infected patients in a human monocytic ehrlichiosis-endemic area. ( 14519250 )
2003
23
Hepatic pathology in human monocytic ehrlichiosis. Ehrlichia chaffeensis infection. ( 12817434 )
2003
24
Human monocytic ehrlichiosis presenting as acute appendicitis during pregnancy. ( 12384854 )
2002
25
Human monocytic ehrlichiosis: similar to Rocky Mountain spotted fever but different. ( 11905291 )
2002
26
Western blot analysis of sera reactive to human monocytic ehrlichiosis and human granulocytic ehrlichiosis agents. ( 11682518 )
2001
27
Human monocytic ehrlichiosis: an emerging pathogen in transplantation. ( 11435982 )
2001
28
Human monocytic ehrlichiosis: a potentially severe disease in children. ( 10922287 )
2000
29
Human monocytic ehrlichiosis in a child with leukemia. ( 10694014 )
2000
30
Outcome of diagnostic tests using samples from patients with culture-proven human monocytic ehrlichiosis: implications for surveillance. ( 10449489 )
1999
31
Human monocytic ehrlichiosis in a thirteen year old: a case report. ( 10478517 )
1999
32
Human monocytic ehrlichiosis presenting as febrile diarrhea. ( 9412975 )
1997
33
Human monocytic ehrlichiosis in children. ( 9200384 )
1997
34
Serologic diagnosis of human monocytic ehrlichiosis by immunoblot analysis. ( 8556515 )
1994

Variations for Human Monocytic Ehrlichiosis

Expression for Human Monocytic Ehrlichiosis

Search GEO for disease gene expression data for Human Monocytic Ehrlichiosis.

Pathways for Human Monocytic Ehrlichiosis

Pathways related to Human Monocytic Ehrlichiosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.74 IL18R1 IL21R

GO Terms for Human Monocytic Ehrlichiosis

Biological processes related to Human Monocytic Ehrlichiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to cytokine stimulus GO:0071345 9.16 IL18R1 NLRP12
2 positive regulation of NIK/NF-kappaB signaling GO:1901224 8.96 IL18R1 NLRP12
3 natural killer cell activation GO:0030101 8.62 IL18R1 IL21R

Sources for Human Monocytic Ehrlichiosis

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28 GO
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32 HPO
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34 ICD10 via Orphanet
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
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74 UMLS via Orphanet
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