MCID: HYD001
MIFTS: 46

Hydranencephaly

Categories: Ear diseases, Eye diseases, Fetal diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Hydranencephaly

MalaCards integrated aliases for Hydranencephaly:

Name: Hydranencephaly 12 74 52 53 58 6 43 15
Hydroanencephaly 52

Characteristics:

Orphanet epidemiological data:

58
hydranencephaly
Prevalence: 1-5/10000 (Worldwide); Age of onset: Antenatal,Neonatal; Age of death: infantile,stillbirth;

Classifications:

Orphanet: 58  
Rare neurological diseases
Developmental anomalies during embryogenesis


External Ids:

Disease Ontology 12 DOID:4626
MeSH 43 D006832
NCIt 49 C98949
SNOMED-CT 67 30023002
ICD10 32 Q04.3
MESH via Orphanet 44 D006832
ICD10 via Orphanet 33 Q04.3
UMLS via Orphanet 72 C0020225
Orphanet 58 ORPHA2177
UMLS 71 C0020225

Summaries for Hydranencephaly

NINDS : 53 Hydranencephaly is a rare condition in which the brain's cerebral hemispheres are absent and replaced by sacs filled with cerebrospinal fluid. An infant with hydranencephaly may appear normal at birth. The infant's head size and spontaneous reflexes such as sucking, swallowing, crying, and moving the arms and legs may all seem normal. However, after a few weeks the infant usually becomes irritable and has increased muscle tone. After a few months of life, seizures and hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain) may develop. Other symptoms may include visual impairment, lack of growth, deafness, blindness, spastic quadriparesis (paralysis), and intellectual deficits. Hydranencephaly is considered to be an extreme form of porencephaly (a rare disorder characterized by a cyst or cavity in the cerebral hemispheres) and may be caused by vascular infections or traumatic disorders after the 12th week of pregnancy. Diagnosis may be delayed for several months because early behavior appears to be relatively normal. Some infants may have additional abnormalities at birth including seizures, myoclonus (spasm or twitching of a muscle or group of muscles), and respiratory problems.

MalaCards based summary : Hydranencephaly, also known as hydroanencephaly, is related to proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome and lissencephaly. An important gene associated with Hydranencephaly is WDR81 (WD Repeat Domain 81), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. The drugs Acetylcholine and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and eye, and related phenotypes are global developmental delay and intrauterine growth retardation

NIH Rare Diseases : 52 Hydranencephaly is a rare condition in which the brain's cerebral hemispheres are absent and replaced by sacs filled with cerebrospinal fluid (CSF) . Affected infants may appear and act normal at birth, but irritability and hypertonia often develop within a few weeks. Other signs and symptoms may include seizures , hydrocephalus , visual impairment, lack of growth, deafness, blindness, paralysis, and intellectual disabilities . Prognosis is typically poor with many affected children dying before one year of age. In rare cases, children may survive for several years or more. It has been suspected to be an inherited condition, although some researchers believe it may be caused by prenatal blockage of the carotid artery where it enters the cranium. Treatment is generally symptomatic and supportive; hydrocephalus may be treated with a shunt.

Wikipedia : 74 Hydranencephaly is a condition in which the brain's cerebral hemispheres are absent to a great degree... more...

Related Diseases for Hydranencephaly

Diseases related to Hydranencephaly via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 143, show less)
# Related Disease Score Top Affiliating Genes
1 proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome 34.9 LOC102724153 FLVCR2
2 lissencephaly 29.8 TUBA1A TMTC3 PAFAH1B1 NDE1 ARX
3 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 12.8
4 lethal hydranencephaly-diaphragmatic hernia syndrome 12.2
5 lissencephaly, x-linked, 2 12.0
6 microhydranencephaly 11.9
7 hydrocephalus, congenital, 1 11.5
8 partington x-linked mental retardation syndrome 11.2
9 x-linked lissencephaly with abnormal genitalia 11.2
10 hydrocephalus 10.6
11 alkuraya-kucinskas syndrome 10.6
12 congenital amyoplasia 10.6
13 cerebellar hypoplasia 10.4
14 tubulinopathy-associated dysgyria 10.4 TUBB2B TUBA1A
15 porencephaly 10.4
16 holoprosencephaly 10.4
17 posterior column ataxia 10.4 LOC102724153 FLVCR2 FLVCR1
18 encephalopathy 10.3
19 posterior column ataxia with retinitis pigmentosa 10.3 LOC102724153 FLVCR2 FLVCR1
20 paralytic squint 10.3 TUBB2B TUBA1A
21 pachygyria 10.3 TUBA1A PAFAH1B1
22 neuronal migration disorders 10.3 TUBA1A PAFAH1B1
23 cerebellar ataxia, mental retardation, and dysequilibrium syndrome 1 10.3 WDR81 TUBB2B
24 toxoplasmosis 10.3
25 alobar holoprosencephaly 10.3
26 lissencephaly with cerebellar hypoplasia 10.3 PAFAH1B1 ARX
27 yemenite deaf-blind hypopigmentation syndrome 10.2
28 fowler urethral sphincter dysfunction syndrome 10.2
29 lissencephaly, x-linked, 1 10.2 PAFAH1B1 ARX
30 microlissencephaly 10.2 WDR81 TUBB2B TUBA1A NDE1
31 microcephaly 10.2
32 encephalitis 10.2
33 tubulinopathies 10.2 TUBG1 TUBB2B TUBA1A
34 diarrhea 10.1
35 congenital toxoplasmosis 10.1
36 herpes simplex 10.1
37 rubella 10.1
38 diabetes insipidus 10.1
39 chromosome 17p13.3, centromeric, duplication syndrome 10.1 WDR81 PAFAH1B1
40 lissencephaly 2 10.1 TUBB2B TUBA1A PAFAH1B1 ARX
41 tukel syndrome 10.1 WDR81 TUBG1 TUBB2B TUBA1A
42 infancy electroclinical syndrome 10.1 PAFAH1B1 ARX
43 anencephaly 10.0
44 schizencephaly 10.0
45 polymicrogyria with or without vascular-type ehlers-danlos syndrome 10.0
46 visual epilepsy 10.0
47 hypothyroidism 10.0
48 encephalomalacia 10.0
49 nervous system disease 10.0
50 cleft lip 10.0
51 pathologic nystagmus 10.0
52 polymicrogyria 10.0
53 congenital hydrocephalus 10.0
54 congenital rubella 10.0
55 polymyositis 10.0
56 anoxia 10.0
57 seizure disorder 10.0
58 cleft lip/palate 10.0
59 physical disorder 10.0 TUBA1A PAFAH1B1 NDE1
60 spastic cerebral palsy 10.0 TUBA1A COL4A1
61 miller-dieker lissencephaly syndrome 10.0 TUBB2B TUBA1A PAFAH1B1 NDE1 ARX
62 congenital nervous system abnormality 9.9 TUBB2B TUBA1A PAFAH1B1 NDE1 ARX
63 dicarboxylic aminoaciduria 9.9 SLC35E1 SLC35C2 SLC35B1 SLC35A5
64 cleft palate, isolated 9.9
65 systemic lupus erythematosus 9.9
66 myositis 9.9
67 optic nerve hypoplasia, bilateral 9.9
68 septooptic dysplasia 9.9
69 strabismus 9.9
70 chromosome 2q35 duplication syndrome 9.9
71 aprosencephaly syndrome 9.9
72 hydrops fetalis, nonimmune 9.9
73 3-methylglutaconic aciduria, type iii 9.9
74 peho syndrome 9.9
75 pituitary hormone deficiency, combined, 2 9.9
76 multiple pterygium syndrome, escobar variant 9.9
77 roberts syndrome 9.9
78 sudden infant death syndrome 9.9
79 fryns microphthalmia syndrome 9.9
80 branchiootic syndrome 1 9.9
81 brittle bone disorder 9.9
82 bone mineral density quantitative trait locus 3 9.9
83 rhabdoid tumor predisposition syndrome 1 9.9
84 hydrops, lactic acidosis, and sideroblastic anemia 9.9
85 peho-like syndrome 9.9
86 west syndrome 9.9
87 exanthem 9.9
88 autosomal recessive disease 9.9
89 aphasia 9.9
90 scoliosis 9.9
91 ptosis 9.9
92 zika fever 9.9
93 endocarditis 9.9
94 microphthalmia 9.9
95 murray valley encephalitis 9.9
96 japanese encephalitis 9.9
97 spastic quadriplegia 9.9
98 disseminated intravascular coagulation 9.9
99 oligohydramnios 9.9
100 neutropenia 9.9
101 locked-in syndrome 9.9
102 quadriplegia 9.9
103 rift valley fever 9.9
104 basilar artery occlusion 9.9
105 coccidioidomycosis 9.9
106 cholestasis 9.9
107 mitral valve stenosis 9.9
108 cerebral palsy 9.9
109 hepatitis 9.9
110 cystic lymphangioma 9.9
111 rhabdoid cancer 9.9
112 loeffler endocarditis 9.9
113 myopathy 9.9
114 pituitary hypoplasia 9.9
115 muscular atrophy 9.9
116 carotid artery occlusion 9.9
117 polyhydramnios 9.9
118 vasculitis 9.9
119 lupus erythematosus 9.9
120 chorioretinitis 9.9
121 mechanical strabismus 9.9
122 hypopituitarism 9.9
123 intracranial hypertension 9.9
124 placental abruption 9.9
125 hypereosinophilic syndrome 9.9
126 bobble-head doll syndrome 9.9
127 cerebellar agenesis 9.9
128 congenital cytomegalovirus 9.9
129 congenital intrauterine infection-like syndrome 9.9
130 encephalocele 9.9
131 penoscrotal transposition 9.9
132 torch syndrome 9.9
133 cytomegalovirus infection 9.9
134 megalencephaly 9.9
135 spasticity 9.9
136 tremor 9.9
137 occipital encephalocele 9.9
138 renal dysplasia 9.9
139 rare surgical neurologic disease 9.9
140 rare movement disorder 9.9
141 walker-warburg syndrome 9.9 TUBB2B TUBA1A TMTC3 PAFAH1B1 COL4A1
142 band heterotopia 9.8 TUBG1 TUBB2B TUBA1A PAFAH1B1 NDE1
143 periventricular nodular heterotopia 9.6 TUBG1 TUBB2B TUBA1A TMTC3 PAFAH1B1 NDE1

Graphical network of the top 20 diseases related to Hydranencephaly:



Diseases related to Hydranencephaly

Symptoms & Phenotypes for Hydranencephaly

Human phenotypes related to Hydranencephaly:

58 31 (showing 31, show less)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 global developmental delay 58 31 hallmark (90%) Very frequent (99-80%) HP:0001263
2 intrauterine growth retardation 58 31 hallmark (90%) Very frequent (99-80%) HP:0001511
3 cerebral cortical atrophy 58 31 hallmark (90%) Very frequent (99-80%) HP:0002120
4 blindness 58 31 hallmark (90%) Very frequent (99-80%) HP:0000618
5 postnatal growth retardation 58 31 hallmark (90%) Very frequent (99-80%) HP:0008897
6 infantile sensorineural hearing impairment 58 31 hallmark (90%) Very frequent (99-80%) HP:0008610
7 abnormal corpus striatum morphology 58 31 hallmark (90%) Very frequent (99-80%) HP:0010994
8 seizures 58 31 frequent (33%) Frequent (79-30%) HP:0001250
9 meningitis 58 31 frequent (33%) Frequent (79-30%) HP:0001287
10 lethargy 58 31 frequent (33%) Frequent (79-30%) HP:0001254
11 hypotelorism 58 31 frequent (33%) Frequent (79-30%) HP:0000601
12 spastic diplegia 58 31 frequent (33%) Frequent (79-30%) HP:0001264
13 opisthotonus 58 31 frequent (33%) Frequent (79-30%) HP:0002179
14 stiff neck 58 31 frequent (33%) Frequent (79-30%) HP:0025258
15 dilatation of the ventricular cavity 58 31 frequent (33%) Frequent (79-30%) HP:0006698
16 antenatal intracerebral hemorrhage 58 31 frequent (33%) Frequent (79-30%) HP:0007023
17 abnormal cerebral artery morphology 58 31 frequent (33%) Frequent (79-30%) HP:0009145
18 abnormal dura mater morphology 58 31 frequent (33%) Frequent (79-30%) HP:0010652
19 abnormality of fontanelles 58 31 frequent (33%) Frequent (79-30%) HP:0011328
20 thalamic edema 58 31 frequent (33%) Frequent (79-30%) HP:0025040
21 dysgenesis of the thalamus 58 31 frequent (33%) Frequent (79-30%) HP:0025099
22 hypoplastic hippocampus 58 31 frequent (33%) Frequent (79-30%) HP:0025517
23 atrophic pituitary gland 58 31 frequent (33%) Frequent (79-30%) HP:0410279
24 abnormal internal carotid artery morphology 58 31 frequent (33%) Frequent (79-30%) HP:3000062
25 congenital microcephaly 58 31 occasional (7.5%) Occasional (29-5%) HP:0011451
26 ventriculomegaly 58 31 occasional (7.5%) Occasional (29-5%) HP:0002119
27 optic nerve hypoplasia 58 31 occasional (7.5%) Occasional (29-5%) HP:0000609
28 chorioretinal atrophy 58 31 occasional (7.5%) Occasional (29-5%) HP:0000533
29 abnormality of vision 58 Excluded (0%)
30 hyporeflexia 58 Excluded (0%)
31 abnormality of the falx cerebri 58 Excluded (0%)

Drugs & Therapeutics for Hydranencephaly

Drugs for Hydranencephaly (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 9, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 2, Phase 3 51-84-3 187
2 Neurotransmitter Agents Phase 2, Phase 3
3 incobotulinumtoxinA Phase 2, Phase 3
4 abobotulinumtoxinA Phase 2, Phase 3
5 Acetylcholine Release Inhibitors Phase 2, Phase 3
6 Neuromuscular Agents Phase 2, Phase 3
7 Botulinum Toxins Phase 2, Phase 3
8 Cholinergic Agents Phase 2, Phase 3
9 Botulinum Toxins, Type A Phase 2, Phase 3

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Open Label Pilot Study to Treat Women With Chronic Urinary Retention or Voiding Dysfunction Due to a Primary Disorder of Sphincter Relaxation (Fowler's Syndrome) With Outpatient Urethral Injections of Botulinum Toxin A (BoNT-A) Completed NCT02428881 Phase 2, Phase 3 onabotulinumtoxinA

Search NIH Clinical Center for Hydranencephaly

Cochrane evidence based reviews: hydranencephaly

Genetic Tests for Hydranencephaly

Anatomical Context for Hydranencephaly

MalaCards organs/tissues related to Hydranencephaly:

40
Brain, Pituitary, Eye, Bone, Thalamus, Cortex, Heart

Publications for Hydranencephaly

Articles related to Hydranencephaly:

(showing 495, show less)
# Title Authors PMID Year
1
Management and problems of prolonged survival with hydranencephaly in the modern treatment era. 61
31897631 2020
2
Prenatal sonographic diagnosis of Dandy-Walker malformation and type III lissencephaly: A novel association. 61
31859376 2019
3
Clinical cases of Bluetongue serotype 8 in calves in France in the 2018-2019 winter. 61
31883429 2019
4
Involvement of the centrosomal protein 55 (cep55) gene in zebrafish head formation. 61
31365163 2019
5
Hydranencephaly complicated by central diabetes insipidus: report of two cases and systematic review of literature. 61
30929071 2019
6
The Benefits of a Guideline on Safe Termination of Pregnancy for Legal Indications: An Illustrative Case Report of a Hydranencephaly. 61
31433602 2019
7
An unusual presentation of bobble-head doll syndrome in a patient with hydranencephaly and Chiari 3 malformation. 61
30726525 2019
8
An Amish founder variant consolidates disruption of CEP55 as a cause of hydranencephaly and renal dysplasia. 61
30622327 2019
9
Phenotypic spectrum of NDE1-related disorders: from microlissencephaly to microhydranencephaly. 61
30637988 2019
10
First genomic detection of Peaton virus in a calf with hydranencephaly in Israel. 61
30394673 2019
11
Schmallenberg virus: a systematic international literature review (2011-2019) from an Irish perspective. 61
31624588 2019
12
Schmallenberg virus affects T-bet, Gata3, RoRrγt, Foxp3 and Eomes in mice brain. 61
31507194 2019
13
Fowler syndrome and fetal MRI findings: a genetic disorder mimicking hydranencephaly/hydrocephalus. 61
29541808 2018
14
Proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome or Fowler syndrome: Report of a family and insight into the disease's mechanism. 61
29500860 2018
15
Seroprevalence of Schmallenberg virus in dairy cattle in Ethiopia. 61
29111139 2018
16
[Treatment with sublingual desmopressin in two infants with hydranencephaly and central diabetes insipidus]. 61
29333830 2018
17
Teratogenic bluetongue and related orbivirus infections in pregnant ruminant livestock: timing and pathogen genetics are critical. 61
29107849 2017
18
Choroid plexus cauterization on treatment of hydranencephaly and maximal hydrocephalus. 61
28597309 2017
19
Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay. 61
29042871 2017
20
Congenital arthrogryposis-hydranencephaly syndrome caused by Akabane virus in newborn calves of Basrah Governorate, Iraq. 61
29062207 2017
21
Evidence of extensive renewed Schmallenberg virus circulation in Belgium during summer of 2016 - increase in arthrogryposis-hydranencephaly cases expected. 61
28474485 2017
22
Heparan Sulfate Proteoglycan Is an Important Attachment Factor for Cell Entry of Akabane and Schmallenberg Viruses. 61
28539443 2017
23
A large-scale serological survey of Akabane virus infection in cattle, yak, sheep and goats in China. 61
28757043 2017
24
A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis. 61
28264986 2017
25
Diagnosis and treatment of herpes simplex 1 virus infection in pregnancy. 61
28680463 2017
26
Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening program. 61
28153665 2017
27
Hydranencephaly in Monochorionic-Diamniotic Twins. 61
27876178 2017
28
Characterization of Shuni viruses detected in Israel. 61
27540741 2016
29
Prevalence of Antibodies to Zika Virus in Mothers from Hawaii Who Delivered Babies with and without Microcephaly between 2009-2012. 61
27997547 2016
30
A novel homozygous variant in SERPINH1 associated with a severe, lethal presentation of osteogenesis imperfecta with hydranencephaly. 61
27677223 2016
31
A lethal phenotype associated with tissue plasminogen deficiency in humans. 61
27417437 2016
32
A Case of Hydranencephaly in Which Ophthalmic Examinations Were Performed. 61
27790130 2016
33
Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal Demise. 61
26914330 2016
34
Seroprevalence of Schmallenberg virus infection in sheep and goats flocks in Germany, 2012-2013. 61
29067177 2016
35
Neuroepidemiology of Porencephaly, Schizencephaly, and Hydranencephaly in Miyagi Prefecture, Japan. 61
26545857 2016
36
Mutations in FLVCR2 associated with Fowler syndrome and survival beyond infancy. 61
25677735 2016
37
SEVERE HYDROCEPHALUS, KIDNEY AND SKELETAL ANOMALIES IN A FEMALE PATIENT WITH MILD NEUROLOGICAL ALTERATIONS. 61
30204973 2016
38
Schmallenberg disease in sheep or goats: Past, present and future. 61
26441013 2015
39
Profound Bradycardia After Intrathecal Baclofen Injection in a Patient With Hydranencephaly. 61
26411756 2015
40
Ovine and Bovine Congenital Abnormalities Associated With Intrauterine Infection With Schmallenberg Virus. 61
25428409 2015
41
[Vascular disruption birth defects are not associated to chromosomal alterations]. 61
27311163 2015
42
TUBA1A mutation can cause a hydranencephaly-like severe form of cortical dysgenesis. 61
26493046 2015
43
Generation of a Recombinant Akabane Virus Expressing Enhanced Green Fluorescent Protein. 61
26157127 2015
44
Virus-induced congenital malformations in cattle. 61
26399846 2015
45
Central nervous system injury in utero: selected entities. 61
26346151 2015
46
Akabane virus infection. 61
26601444 2015
47
Hydranencephaly in a case of suspected infanticide. 61
24934161 2015
48
Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants. 61
25799514 2015
49
Hydranencephaly in a newborn with a FLVCR2 mutation and prenatal exposure to cocaine. 61
25131804 2015
50
Hydranencephaly: Considering Prolonged Survival and Treatment by Endoscopic Choroid Plexus Coagulation. 61
26442548 2015
51
Endoscopic coagulation of choroid plexus in three children with severely advanced forms of hydrocephalus. 61
24202962 2015
52
Congenital multi-organ malformations in a Holstein calf. 61
26893818 2015
53
Genotype-phenotype correlation in neuronal migration disorders and cortical dysplasias. 61
26052266 2015
54
Viral emergence and consequences for reproductive performance in ruminants: two recent examples (bluetongue and Schmallenberg viruses). 61
25472045 2014
55
Neuropathological microscopic features of abortions induced by Bunyavirus / or Flavivirus infections. 61
25425524 2014
56
Hydranencephaly: cerebral spinal fluid instead of cerebral mantles. 61
25326191 2014
57
Consciousness without cortex: a hydranencephaly family survey. 61
24942496 2014
58
18F-FDG PET/CT in a 16-year-old patient with hydranencephaly. 61
24395017 2014
59
Theriogenology question of the month. Dystocia in a mare caused by fetal hydranencephaly. 61
25181265 2014
60
Obliteration of the choroid plexus after endoscopic coagulation. 61
24995821 2014
61
Volumetric analysis of cerebrospinal fluid and brain parenchyma in a patient with hydranencephaly and macrocephaly--case report. 61
25165052 2014
62
Choroid plexus coagulation in infants with extreme hydrocephalus or hydranencephaly. 61
24766307 2014
63
Endoscopic coagulation of choroid plexus in hydranencephaly. 61
25237437 2014
64
Malformations among the X-linked intellectual disability syndromes. 61
24166814 2013
65
Hydranencephaly. 61
23945496 2013
66
Hydranencephaly: a rare cause of delayed developmental milestones. 61
23632619 2013
67
Fetal magnetic resonance imaging in hydranencephaly. 61
23574557 2013
68
Schmallenberg virus, a novel orthobunyavirus infection in ruminants in Europe: potential global impact and preventive measures. 61
23215779 2013
69
Looking at the missing brain: hydranencephaly case series and literature review. 61
23337012 2013
70
Immunophenotyping of inflammatory cells associated with Schmallenberg virus infection of the central nervous system of ruminants. 61
23667545 2013
71
Hemihydranencephaly: living with half brain dysfunction. 61
23324549 2013
72
Choroid plexus coagulation for hydrocephalus not due to CSF overproduction: a review. 61
23151740 2013
73
Schmallenberg virus. 61
23689895 2013
74
Transplacental transmission of Bluetongue virus serotype 1 and serotype 8 in sheep: virological and pathological findings. 61
24358112 2013
75
Hydranencephaly: a rare cause of an enlarging head size in an infant. 61
23112982 2012
76
Long-term outcome for endoscopic third ventriculostomy alone or in combination with choroid plexus cauterization for congenital aqueductal stenosis in African infants. 61
22747094 2012
77
Hydranencephaly, pituitary hypoplasia, and anophthalmia in a male infant. 61
22610272 2012
78
Salient lesions in domestic ruminants infected with the emerging so-called Schmallenberg virus in Germany. 61
22610033 2012
79
Prenatal sonography in hydranencephaly: findings during the early stages of disease. 61
22535728 2012
80
Porencephaly and hydranencephaly in six dogs. 61
22186380 2012
81
Assessment of fetomaternal hemorrhage by Kleihauer-Betke test, flow cytometry and α-fetoprotein after invasive obstetric procedures. 61
23157029 2012
82
Endoscopic choroid plexus coagulation in infants with hydranencephaly or hydrocephalus with a minimal cortical mantle. 61
22832209 2012
83
A rare variation of hydranencephaly: case report. 61
24627761 2012
84
Delayed diagnosis of hydranencephaly in a nine-month-old child. 61
24765326 2011
85
Meningocerebral angiodysplasia with metanephric induction failure: Broadening the spectrum of an emerging maldevelopmental syndrome. 61
21664057 2011
86
Congenital hydranencephaly and cerebellar hypoplasia in water buffalo in southern Brazil. 61
21908300 2011
87
Neuropathologic study of border disease virus in naturally infected fetal and neonatal small ruminants and its association with apoptosis. 61
20460448 2011
88
Sporadic COL4A1 mutations with extensive prenatal porencephaly resembling hydranencephaly. 61
21357838 2011
89
Magnetic resonance imaging of intracranial malformations in dogs and cats. 61
21392155 2011
90
Hydranencephaly associated with cerebellar involvement and bilateral microphthalmia and colobomas. 61
20577730 2011
91
An unusual case of hydranencephaly presenting with an anterior midline cyst, a posterior calcified mass, cerebellar hypoplasia and occlusion of the posterior cerebral arteries. 61
21104240 2011
92
Poland anomaly and hydranencephaly: An unusual association. 61
21108405 2010
93
Sonographic diagnosis of brain malformations, part 2: holoprosencephaly - hydranencephaly - agenesis of septum pellucidum - schizencephaly - septo-optical dysplasia. 61
21117007 2010
94
Hydranencephaly vs hydrocephalus. 61
20871431 2010
95
Examining the evidence for vascular pathogenesis of selected birth defects. 61
20815034 2010
96
High-throughput sequencing of a 4.1 Mb linkage interval reveals FLVCR2 deletions and mutations in lethal cerebral vasculopathy. 61
20690116 2010
97
[Topics of brain malformation and epilepsy--age-dependent epileptic encephalopathies and interneuronopathies]. 61
20845763 2010
98
Frameshift mutations of the ARX gene in familial Ohtahara syndrome. 61
20384723 2010
99
Bluetongue virus serotype 8-associated hydranencephaly in two calves in south-eastern England. 61
20693506 2010
100
Postoperative fatal hypothermia in hydranencephaly with pre-operative hypothermia and a nerve palsy: a case report and review of the literature. 61
23457850 2010
101
Post-mortem magnetic resonance imaging and its irreplaceable role in determining CNS malformation (hydranencephaly)--case report. 61
19394772 2010
102
Mutations in FLVCR2 are associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (Fowler syndrome). 61
20206334 2010
103
The cavum septi pellucidi: why is it important? 61
20194938 2010
104
Endoscopic choroid plexus cauterization versus ventriculoperitoneal shunt for hydranencephaly and near hydranencephaly: a prospective study. 61
20173541 2010
105
Fowler syndrome-a clinical, radiological, and pathological study of 14 cases. 61
20014121 2010
106
Hydranencephaly. 61
21209513 2010
107
Refining the clinicopathological pattern of cerebral proliferative glomeruloid vasculopathy (Fowler syndrome): report of 16 fetal cases. 61
19635601 2009
108
Prenatal stroke. 61
19664975 2009
109
Idiopathic hypereosinophilia syndrome with loeffler endocarditis, embolic cerebral infarction, and left hydranencephaly: a case report. 61
19960966 2009
110
Low bispectral index values in hydranencephaly. 61
19395974 2009
111
Epizootic congenital hydranencephaly and abortion in cattle due to bluetongue virus serotype 8 in the Netherlands. 61
19522347 2009
112
Pattern of childhood neuronal migrational disorders in Oman. 61
21048602 2009
113
Fowler syndrome presenting as a Dandy-Walker malformation: a second case report. 61
18702566 2009
114
[Case of a Japanese female presenting severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN) syndrome with a K650M mutation in the fibroblast growth factor receptor 3 gene]. 61
19039991 2008
115
Bluetongue virus serotype 8-associated congenital hydranencephaly in calves. 61
18503510 2008
116
Hydranencephaly in neonates. 61
19054923 2008
117
[Bluetongue virus serotype 8 (BTV-8)-associated brain malformations in two calves]. 61
18717057 2008
118
The presence of consciousness in the absence of the cerebral cortex. 61
18435419 2008
119
Bovine epizootic encephalomyelitis caused by Akabane virus in southern Japan. 61
18554406 2008
120
Chorioretinal dysplasia, hydranencephaly, and intracranial calcifications: pseudo-TORCH or a new syndrome? 61
18084237 2008
121
Hydranencephaly associated with interruption of bilateral internal carotid arteries. 61
18947016 2008
122
Hydranencephaly in a newborn with basilar artery occlusion: MRI findings. 61
25610026 2008
123
Cleavage of Akabane virus S RNA in the brain of infected ruminants. 61
18246421 2008
124
Concurrent peste des petits ruminants virus and pestivirus infection in stillborn twin lambs. 61
18424832 2008
125
First trimester three-dimensional transvaginal imaging of alobar holoprosencephaly associated with proboscis and hypotelorism (ethmocephaly) in a 46,XX fetus. 61
18230123 2008
126
Decreasing trend in postneonatal mortality. 61
18216862 2008
127
Hydranencephaly in calves following the bluetongue serotype 8 epidemic in the Netherlands. 61
18375990 2008
128
Life expectancy in hydranencephaly. 61
18201820 2008
129
Prolonged survival to adulthood of an individual with hydranencephaly. 61
18222607 2008
130
Cerebral blindness and plasticity of the visual system in children. A review of visual capacities in patients with occipital lesions, hemispherectomy or hydranencephaly. 61
18997313 2008
131
Preservation of brainstem neurophysiological function in hydranencephaly. 61
17719607 2007
132
Comparison of Akabane virus isolated from sentinel cattle in Japan. 61
17467929 2007
133
A rare association of hydranencephaly with congenital rubella syndrome. 61
17785910 2007
134
A case of partial 14q- with facial features of holoprosencephaly and hydranencephaly. 61
17628223 2007
135
Brainstem mediation of the stapedius muscle reflex in hydranencephaly. 61
17453476 2007
136
Pattern of childhood epilepsies with neuronal migrational disorders in Oman. 61
17092459 2006
137
Multiple thromboembolic events in fetofetal transfusion syndrome in triplets contributing to the understanding of pathogenesis of hydranencephaly in combination with polymicrogyria. 61
16997352 2006
138
Hydranencephaly with cholestasis and giant hepatitis. 61
17063118 2006
139
Highly effective inhibition of Akabane virus replication by siRNA genes. 61
16616390 2006
140
Intrauterine fetal death of one of twins, coexisting with hydranencephaly in the surviving co-twin: a case report. 61
17191429 2006
141
Pathological findings in a captive colony of maras (Dolichotis patagonum). 61
16731703 2006
142
Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development. 61
16492743 2006
143
Detection of fetal structural abnormalities by an 11-14-week ultrasound dating scan in an unselected Swedish population. 61
16862467 2006
144
Left-hemispheric hydranencephaly with less favorable findings. 61
16322193 2005
145
Early ultrasonographic changes in Fowler syndrome features and review of the literature. 61
16231307 2005
146
XK-aprosencephaly and related entities. 61
16208689 2005
147
Maternal systemic lupus erythematosus and hydranencephaly in a neonate: a case report. 61
16318981 2005
148
Living a normal life with the nondominant hemisphere: magnetic resonance imaging findings and clinical outcome for a patient with left-hemispheric hydranencephaly. 61
15995064 2005
149
Electroencephalography, Doppler vascular scanning, and single photon emission computed tomography in a child with hydranencephaly and intractable seizures. 61
15968932 2005
150
Ultrasound and MRI appearance and evolution of hydranencephaly in utero: a case report. 61
15730175 2005
151
Hydranencephaly with extensive periventricular necrosis and numerous ectopic glioneuronal nests. 61
15641591 2004
152
CT angiography in a newborn child with hydranencephaly. 61
15329738 2004
153
Arthrogryposis, hydranencephaly and cerebellar hypoplasia syndrome in neonatal calves resulting from intrauterine infection with Aino virus. 61
15369656 2004
154
[Hydranencephaly. Findings from computerised axial tomography and magnetic resonance scans]. 61
15340904 2004
155
Serological and clinical evidence of a teratogenic Simbu serogroup virus infection of cattle in Israel, 2001-2003. 61
20419647 2004
156
Serological evidence of akabane virus infection in northern Israel in 2001. 61
15133276 2004
157
Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation. 61
14722918 2004
158
Prenatal sonographic diagnosis of fetal death and hydranencephaly in two Chihuahua fetuses. 61
14599174 2003
159
Prolonged survival in hydranencephaly: a case report. 61
14513530 2003
160
Polymerase chain reaction (PCR) amplification of parvoviral DNA from the brains of dogs and cats with cerebellar hypoplasia. 61
12892305 2003
161
Polymicrogyria in monozygous twins and an elder sibling. 61
12828405 2003
162
Hydranencephaly owing to twin-twin transfusion: serial fetal ultrasonography and magnetic resonance imaging findings. 61
12822826 2003
163
Re: First-trimester features of Fowler syndrome (hydrocephaly-hydranencephaly proliferative vasculopathy). 61
12704756 2003
164
A patient with hydranencephaly and PEHO-like dysmorphic features. 61
12818526 2003
165
First-trimester features of Fowler syndrome (hydrocephaly-hydranencephaly proliferative vasculopathy). 61
12493052 2002
166
Is it Hydranencephaly - A Variant? 61
27407427 2002
167
Choroid plexectomy reduces neurosurgical intervention in patients with hydranencephaly. 61
11919449 2002
168
Teratogenicity of a mutagenised Rift Valley fever virus (MVP 12) in sheep. 61
12092782 2002
169
Two siblings with early onset fetal akinesia deformation sequence and hydranencephaly: further evidence for autosomal recessive inheritance of hydranencephaly, fowler type. 61
11857548 2002
170
Long-term functional evaluation of congenital hydrocephalus in infants and children. 61
12471728 2002
171
Transorbital echoencephalography in cattle. 61
11866047 2002
172
Hydranencephaly in an infant with vascular malformations. 61
11754063 2001
173
[Cerebral CT scan alterations in children with ocular lesions caused by congenital toxoplasmosis] 61
14647827 2001
174
Fetal magnetic resonance imaging (MRI) of ischemic brain injury. 61
11559908 2001
175
Hemihydranencephaly: case report and literature review. 61
11305691 2001
176
Prolonged survival with hydranencephaly: report of two patients and literature review. 61
10963978 2000
177
Serial sonographic features of a fetus with hydranencephaly from 11 weeks to term. 61
11084971 2000
178
Special imaging casebook. Hydranencephaly. 61
10879346 2000
179
Hydranencephaly in Malawian children. 61
12858931 2000
180
Preferential infection of neuronal and astroglia cells by Akabane virus in primary cultures of fetal bovine brain. 61
10781726 2000
181
The novel genetic disorder microhydranencephaly maps to chromosome 16p13.3-12.1. 61
10762554 2000
182
Central nervous system in twin reversed arterial perfusion sequence with special reference to examination of the brain in acardius anceps. 61
10716747 2000
183
A pathologic study on ocular disorders in calves in southern Kyushu, Japan. 61
10720184 2000
184
Actualities in hydrocephalus classification and management possibilities. 61
10672591 2000
185
[Hydranencephaly]. 61
11043345 2000
186
[Encephaloclastic hydranencephaly]. 61
11043358 2000
187
[Hydranencephaly. (Severe cerebral malformations in three newborn infants)]. 61
10647275 1999
188
[Hydranencephaly. A case report]. 61
10797932 1999
189
Hydranencephaly and cerebellar hypoplasia in two kittens attributed to intrauterine parvovirus infection. 61
10373292 1999
190
Encephalopathy in suckling mice infected with Kasba (Chuzan) virus. 61
10213669 1999
191
[Congenital malformations in twins]. 61
10436695 1999
192
Diagnosis please. Case 7: Hydranencephaly. 61
10207424 1999
193
The association between maternal smoking and fetal hydranencephaly. 61
10067012 1999
194
[Disorders of consciousness: the basis for ethical assessment]. 61
10065388 1999
195
Fluid abnormalities occur in the chronically cannulated mid-gestation but not late gestation ovine fetus. 61
9853924 1998
196
Brain functions of an infant with hydranencephaly revealed by auditory evoked potentials. 61
9804025 1998
197
Antepartum fetal intracranial hemorrhage, predisposing factors and prenatal sonography: a review. 61
9759911 1998
198
Central nervous system anomalies. 61
9668696 1998
199
Death in shunted hydrocephalic children in the 1990s. 61
9732242 1998
200
Central nervous system malformations in a perinatal/neonatal autopsy series. 61
10463270 1998
201
[Mismatch negativity of patients with hydranencephaly]. 61
9394600 1997
202
Ultrasonographic study of children suspected of hydrocephalus at the Queen Elizabeth Central Hospital in Blantyre, Malawi. 61
9299833 1997
203
Association of prenatal vascular disruptions with decreased maternal age. 61
9096750 1997
204
Hypothesis: septo-optic dysplasia is a vascular disruption sequence. 61
9096749 1997
205
[Neuroimagings in neuronal migration disorders]. 61
9071189 1997
206
Developmental neuropathology and impact of perinatal brain damage. II: white matter lesions of the neocortex. 61
9056536 1997
207
Teratogenicity of Aino virus in the chick embryo. 61
9243724 1997
208
Decreased maternal age with hydranencephaly. 61
9096748 1997
209
[Multicystic encephalomalacia. Review of 19 cases]. 61
9082884 1997
210
Hydranencephaly with renal dysgenesis: a coincidental finding? Case report with review of the literature. 61
9359650 1997
211
Hydranencephaly, cerebellar hypoplasia, and myopathy in chick embryos infected with aino virus. 61
8952026 1996
212
Deletion (13)(q22) with multiple congenital anomalies, hydranencephaly and penoscrotal transposition. 61
8905192 1996
213
Prenatal sonographic diagnosis of hydranencephaly. 61
8855587 1996
214
Experimental hydranencephaly in the ovine fetus. 61
8740236 1996
215
Proliferation and teratogenicity of Aino virus in chick embryos. 61
8871535 1996
216
The effects of vaccination of Merino ewes with an attenuated Australian bluetongue virus serotype 23 at different stages of gestation. 61
8825310 1995
217
Classification of hydrocephalus and outcome of treatment. 61
8579221 1995
218
[Pattern of the brain damages and its developmental mechanisms in monozygotic twins]. 61
7662409 1995
219
Brain lesions in calves following transplacental infection with bovine-virus diarrhoea virus. 61
7483906 1995
220
The familial syndrome of proliferative vasculopathy and hydranencephaly-hydrocephaly: immunocytochemical and ultrastructural evidence for endothelial proliferation. 61
7770122 1995
221
Partial hydranencephaly in a child coincidental with intrauterine exposure to sodium valproate. 61
7770134 1994
222
A neonatal case of hydranencephaly caused by atheromatous plaque obstruction of aortic arch: possible association with a congenital cytomegalovirus infection? 61
7876942 1994
223
Akabane virus. 61
7728635 1994
224
A congenital abnormality of calves, suggestive of a new type of arthropod-borne virus infection. 61
7884059 1994
225
Monozygous twin with polymicrogyria and normal co-twin. 61
7986297 1994
226
Hydranencephaly in two rhesus monkeys (Macaca mulatta). 61
7869361 1994
227
Porencephaly, hydranencephaly and leukoencephalopathy in ovine fetuses following transplacental infection with bovine virus diarrhoea virus: distribution of viral antigen and characterization of cellular response. 61
8017174 1994
228
Primary congenital rhabdoid tumor of the brain with neoplastic hydranencephaly. 61
8397069 1993
229
Hydranencephaly in newborn calves in Zambia. 61
8357935 1993
230
An outbreak of Akabane virus-induced abnormalities in calves after agistment in an endemic region. 61
8457173 1993
231
Hydranencephaly/multicystic encephalomalacia: association with congenital rubella infection. 61
8375892 1993
232
MRI of the head in the evaluation of microcephaly. 61
8474610 1993
233
Suspected maternal infanticide in a case of hydranencephaly. 61
8518201 1993
234
Web-like malformation of the carotid artery and multicystic encephalomalacia. 61
1437882 1992
235
Evolution of hydranencephaly following intracerebral hemorrhage. 61
1565391 1992
236
Hemi-hydranencephaly with favourable outcome. 61
1592199 1992
237
Electrophysiological study on hydranencephaly. 61
1514661 1992
238
Circadian rhythm in patients with hydranencephaly. 61
1573236 1992
239
Hypoplastic thumbs and hydranencephaly: a new syndrome? 61
1345515 1992
240
Holoprosencephaly with retroprosencephalic extracerebral cyst. 61
1733824 1992
241
Antenatal detection of hydranencephaly at 12 weeks, menstrual age. 61
1309546 1992
242
Damage of maturing brain in the course of toxoplasmic encephalitis. 61
1340923 1992
243
Congenital hydrocephalus--analysis of 49 cases. 61
1844637 1991
244
Severe outcome of brain perfusion failure: a pre-hydranencephalic state? 61
1810162 1991
245
Brain and ocular abnormalities in infants with in utero exposure to cocaine and other street drugs. 61
1709777 1991
246
[Hydranencephaly. Report of a new case]. 61
1871503 1991
247
Evolving fetal hydranencephaly mimicking intracranial neoplasm. 61
2051537 1991
248
Hydranencephaly and maternal cocaine use: a case report. 61
2276252 1990
249
The use of two-dimensional Doppler sonography (color Doppler) in the diagnosis of hydranencephaly. 61
2095306 1990
250
Failure to maintain interspecific pregnancy after transfer of Dall's sheep embryos to domestic ewes. 61
2250237 1990
251
Congenital malformations in sheep resulting from in utero inoculation of Cache Valley virus. 61
2122779 1990
252
An outbreak of congenital hydranencephaly and cerebellar hypoplasia among calves in South Kyushu, Japan: a pathological study. 61
2236906 1990
253
[Electrophysiological studies on hydranencephaly]. 61
2223185 1990
254
Hydranencephaly-cerebellar hypoplasia in a newborn calf after infection of its dam with Chuzan virus. 61
2167994 1990
255
Evidence that Cache Valley virus induces congenital malformations in sheep. 61
2107620 1990
256
Agnathia malformation complex associated with a cystic distention of the oral cavity and hydranencepahly. 61
2074276 1990
257
Prenatal ultrasonic detection of anomalies with a lethal or disastrous outcome. 61
2404299 1990
258
[Endocrinological analysis of chronic hypernatremia in two cases of hydranencephaly]. 61
2294950 1990
259
[Alobar holoprosencephaly. Prenatal diagnosis and autopsy findings in 2 cases]. 61
2699657 1989
260
Immunohistochemical evaluation of neuronal maturation in untreated fetal hydrocephalus. 61
2483866 1989
261
Congenital central nervous system anomalies. 61
2678293 1989
262
MR of hydranencephaly. 61
2505572 1989
263
Intrauterine herpes simplex virus infection. Hydranencephaly and a nonvesicular rash in an infant. 61
2767839 1989
264
Hydranencephaly and maximal hydrocephalus: usefulness of electrophysiological studies for their differentiation. 61
2715606 1989
265
[Congenital anomalies of the brain in computed tomography]. 61
2769827 1989
266
[Hydranencephaly and ingestion of estrogens during pregnancy]. 61
2735810 1989
267
Evoked potentials and Doppler vascular studies in hydranencephaly. 61
2595382 1989
268
Absence of the septum pellucidum: a useful sign in the diagnosis of congenital brain malformations. 61
2783514 1989
269
Ovine arthrogryposis and central nervous system malformations associated with in utero Cache Valley virus infection: spontaneous disease. 61
2492399 1989
270
Laboratory investigation of a naturally occurring outbreak of arthrogryposis-hydranencephaly in Texas sheep. 61
2488650 1989
271
Cerebral ischemia in the developing primate fetus. 61
2730600 1989
272
Porencephaly and hydranencephaly: a neuropathological study of four autopsy cases. 61
2923267 1989
273
Antenatal diagnosis of fetal intracranial anomalies. 61
2681372 1989
274
Intrauterine diagnosis of hydranencephaly by magnetic resonance. 61
2645499 1989
275
[Hydranencephaly: report of a case]. 61
2491379 1989
276
Serologic evidence for the etiologic role of Chuzan virus in an epizootic of congenital abnormalities with hydranencephaly-cerebellar hypoplasia syndrome of calves in Japan. 61
3239837 1988
277
Two related cases of cerebellar abnormality in equine fetuses associated with hydrops of fetal membranes. 61
3206793 1988
278
Congenital cerebrospinal fluid-containing intracranial abnormalities: a sonographic classification. 61
3152397 1988
279
Pseudoaprosencephaly: Aplasia of the Forebrain in a Median Facial Cleft Syndrome with Arhinia and Anophthalmia. 61
28614610 1988
280
[Hydranencephaly and ingestion of estrogens during pregnancy. Fetal cerebral vascular complication?]. 61
3202672 1988
281
The development of Akabane virus-induced congenital abnormalities in cattle. 61
3137718 1988
282
Ophthalmic findings of hydranencephaly. 61
3294372 1988
283
Akabane disease in sheep. 61
3135792 1988
284
MRI and evoked potentials in a child with hydranencephaly. 61
3242520 1988
285
Epidemiological survey of an epidemic of congenital abnormalities with hydranencephaly-cerebellar hypoplasia syndrome of calves occurring in 1985/86 and seroepidemiological investigations on Chuzan virus, a putative causal agent of the disease, in Japan. 61
2838675 1988
286
Congenital hydranencephaly and arthrogryposis of Corriedale sheep. 61
3390091 1988
287
Myopathy and encephalopathy in chick embryos experimentally infected with Akabane virus. 61
3125658 1988
288
Hydranencephaly. 61
3051087 1988
289
Fetal neuropathology of proliferative vasculopathy and hydranencephaly-hydrocephaly with multiple limb pterygia. 61
3270051 1988
290
[Cerebellar hypoplasia and hydranencephaly in cattle after transplacental bovine diarrhea virus infection]. 61
3322778 1987
291
A lethal presentation of de novo deletion 7q. 61
3119853 1987
292
Isolation of the right subclavian artery with subclavian steal in a child with Klippel-Feil anomaly: an example of the subclavian artery supply disruption sequence. 61
3591838 1987
293
The heterogeneity of the Pena-Shokeir syndrome. 61
3561707 1987
294
The pathogenesis of fetal hypokinesia. A neurological study of 75 cases of congenital contractures with emphasis on cerebral lesions. 61
3561701 1987
295
Intrauterine herpes simplex virus infections. 61
3794894 1987
296
[Hydranencephaly and congenital toxoplasmosis. Apropos of 4 cases]. 61
3658617 1987
297
Recurrent developmental anomalies: 1. Syndrome of hydranencephaly with renal aplastic dysplasia; 2. Polyvalvular developmental heart defect. 61
3130870 1987
298
Lethal multiple pterygium syndrome: report of a new case with hydranencephaly. 61
3789017 1986
299
[Cerebral ultrasound diagnosis in brain abnormalities]. 61
3796635 1986
300
Cerebral cortical contributions to sensory evoked potentials: hydranencephaly. 61
2427316 1986
301
A rare patient with a false median cleft lip associated with multiple congenital anomalies. 61
3078619 1986
302
Hydranencephaly caused by congenital infection with herpes simplex virus. 61
3725658 1986
303
Hydranencephaly after maternal butane-gas intoxication during pregnancy. 61
3721079 1986
304
Ultrasonographic prenatal diagnosis of hydranencephaly. A case report. 61
3519967 1986
305
Complexities of intraventricular abnormalities. 61
3514828 1986
306
Antenatal recognition of cerebral anomalies. 61
3521024 1986
307
Anatomopathology of non-tumoral aqueductal stenosis. 61
3772492 1986
308
Diagnosis of brain neuropathology in utero. 61
3540704 1986
309
Hydranencephaly--radiologic features and anterior pituitary function--a case report. 61
3599932 1986
310
[Experimental production of myeloschisis associated with hindbrain crowding in the central nervous system of rat fetuses by a single intragastric administration of ethylenethiourea]. 61
4085566 1985
311
Lung growth and development in anencephaly and hydranencephaly. 61
4037531 1985
312
Hydranencephaly: US appearance during in utero evolution. 61
4023242 1985
313
A study of the host range and distribution of antibody to Akabane virus (genus bunyavirus, family Bunyaviridae) in Kenya. 61
4020110 1985
314
Possible windborne spread to western Turkey of bluetongue virus in 1977 and of Akabane virus in 1979. 61
2862205 1985
315
Unilateral hydrocephalus combined with occlusion of the ipsilateral internal carotid artery. 61
4012554 1985
316
Hydranencephaly: prenatal and neonatal ultrasonographic appearance. 61
3893452 1985
317
Exencephaly in araucana chickens and silkie bantams. 61
4026741 1985
318
Extreme variant of septo-optic dysplasia. 61
3934619 1985
319
Vascular basis for malformations in a twin. 61
4038867 1985
320
Histological and histochemical observations on the muscular lesions in a newborn calf with hydranencephaly. 61
3981835 1985
321
[Posthemorrhagic hydranencephaly in the fetal period with deficiency of factor XIII (fibrin stabilizing factor)]. 61
4038603 1985
322
Transplacental induction of myeloschisis associated with hindbrain crowding and other malformations in the central nervous system in Long-Evans rats. 61
4042102 1985
323
Hydranencephaly--antenatal diagnosis using ultrasound. 61
6387964 1984
324
Bilateral optic nerve aplasia associated with hydranencephaly. 61
6508094 1984
325
[Hydroanencephaly]. 61
6438972 1984
326
Antenatal ultrasound diagnosis of an unusual case of hydranencephaly. 61
6438176 1984
327
Congenital hydranencephaly/porencephaly due to vascular disruption in monozygotic twins. 61
6709425 1984
328
Real-time ultrasonography in the neonate: a systematic study of a high-risk infants population. 61
6724995 1984
329
[Normal and pathological ultrasonography of the fetal brain]. 61
6730068 1984
330
Murine forebrain anomalies induced by coxsackievirus B3 variants. 61
6096503 1984
331
Intrauterine purulent encephalitis with early stage of hydranencephaly. Case report. 61
6475497 1984
332
[Hydranencephaly. Pathogenetic considerations]. 61
6322716 1983
333
Bluetongue virus-induced hydranencephaly in cattle. 61
6314630 1983
334
Sinusoidal fetal heart rate pattern in hydranencephaly. A case report. 61
6631852 1983
335
Ocular, naso-maxillary, and neural anomalies in raccoons, Procyon lotor (L.). 61
6417348 1983
336
Pathology in the ovine foetus caused by an ovine pestivirus. 61
6311154 1983
337
C.T. diagnosis: hydranencephaly. 61
6576794 1983
338
[CSF dynamics of hydranencephaly]. 61
6194445 1983
339
[Pathology of hydranencephaly]. 61
6870578 1983
340
[Experience in the prenatal diagnosis of hydranencephaly and the follow-up study of the newborn infants]. 61
6398477 1983
341
Destructive lesions of the brain. 61
6605492 1983
342
[Congenital hydrocephalus: clinico-pathological picture]. 61
6100512 1982
343
Development of EEG activity after ten days of electrocerebral inactivity: ten days of electrocerebral inactivity: a case report in a premature neonate-hydranencephaly or massive ventricular enlargement. 61
7172454 1982
344
Bluetongue in western Turkey. 61
6289510 1982
345
Cerebral, renal and splenic lesions due to fetal anoxia and their relationship to malformations. 61
7117710 1982
346
Review. In utero sonographic diagnosis of fetal cerebral anomalies. 61
7046402 1982
347
Hydranencephaly. 61
7174095 1982
348
[Hydranencephaly: clinicopathological study of 6 cases]. 61
7125951 1982
349
Toxoplasmosis and hydranencephaly. 61
7070412 1982
350
Akabane disease in cattle: congenital abnormalities caused by viral infection. Spontaneous disease. 61
7200278 1982
351
Hydranencephaly associated with feline panleukopenia. 61
7200971 1982
352
[Congenital toxoplasmosis with hydranencephaly. A case report (author's transl)]. 61
6278632 1982
353
Body movements during sleep in full-term newborn infants. 61
7065377 1982
354
Hydranencephaly: sleep and movement characteristics. 61
7065376 1982
355
Etiologic heterogeneity in hydranencephaly. 61
7139107 1982
356
[Prenatal diagnosis of hydranencephaly. Clinical case]. 61
7184066 1982
357
Radiological case of the month. Hydranencephaly. 61
7315811 1981
358
Unilateral hydranencephaly: case report. 61
7322337 1981
359
Evaluation of macrocrania using computed tomography. 61
7315809 1981
360
[Congenital toxoplasmosis with hydranencephaly. A case report (author's transl)]. 61
7259014 1981
361
Association of bovine viral diarrhoea virus infection to hydranencephaly and other central nervous system lesions in perinatal calves. 61
7316899 1981
362
Congenital microhydranencephalus in cattle. 61
6260427 1981
363
[Two new cases of triploidy in premature liveborn infants (author's transl)]. 61
7343917 1981
364
Vascular etiology of disruptive structural defects in monozygotic twins. 61
7243457 1981
365
Neutralising antibodies to Akabane virus in ruminants in Cyprus. 61
7256874 1981
366
Percutaneous choroid plexus coagulation in hydranencephaly. 61
7249814 1981
367
Ultrasound evaluation of cystic intracranial lesions in the neonate. 61
6968920 1980
368
Diagnostic image evaluation of hydranencephaly and pictorially similar entities, with emphasis on computed tomography. 61
7422865 1980
369
[Brain teratology as a result of transplacental virus infection in ruminants]. 61
6267276 1980
370
Increase in placental lactogen and somatomedins after nephrectomy. 61
7012225 1980
371
[The etiopathogenesis of hydranencephaly]. 61
7418081 1980
372
Morphogenesis of hydranencephaly and other intracranial malformations in progeny of pregnant ewes infected with pestiviruses. 61
6248579 1980
373
Cerebroarthrodigital syndrome: a newly recognized formal genesis syndrome in three patients with apparent arthromyodysplasia and sacral agenesis, brain malformation and digital hypoplasia. 61
7395897 1980
374
Hydranencephaly in twins. 61
7468930 1980
375
Hydranencephaly versus maximal hydrocephalus: an important clinical distinction. 61
7354898 1980
376
Monozygotic twinning and structural defects. 61
501497 1979
377
Hydranencephaly in a twin gestation. 61
471381 1979
378
[Diagnosis of hydranencephaly]. 61
156690 1979
379
[Diagnostic and etiologic problems of hydranencephaly (author's transl)]. 61
484944 1979
380
Alcohol embryo- and fetopathy. Neuropathology of 3 children and 3 fetuses. 61
438847 1979
381
[Cerebral angiography and computerized tomography in a case of hydranencephaly (author's transl)]. 61
424064 1979
382
Hydranencephaly--clinical and neuropathological aspects. 61
474214 1979
383
Congenital abnormalities in newborn lambs following Akabane virus infection in pregnant ewes. 61
537648 1979
384
Hydranencephaly in vertebral-basilar territory. 61
568869 1978
385
Congenital hydranencephaly and cerebellar hypoplasia in calves. 61
721674 1978
386
Foetal thyroidectomy and hydranencephaly in lambs. 61
718566 1978
387
Postencephalitic porencephaly, hydranencephaly or polymicrogyria. A review. 61
567000 1978
388
Hypoplasia of the optic nerve. 61
678183 1978
389
Bilateral congenital subdural cysts associated with porencephaly and CSF-subdural fistula. A report of two cases. 61
655911 1978
390
Hydranencephaly in association with Roberts syndrome. 61
667753 1978
391
[Angiographic pattern of hydranencephaly (author's transl)]. 61
714737 1978
392
Electrophysiological responses in hydranencephaly. 61
655229 1978
393
Congenital bovine epizootic arthrogryposis and hydranencephaly. 61
687275 1978
394
Hydranencephaly in calves in the natal region. 61
702507 1978
395
[Hydranencephaly in a 4-month-old infant]. 61
634664 1978
396
Deformities of chick embryos in experimental Akabane virus infection. 61
570255 1978
397
Aural temperature of the newborn infant. 61
596924 1977
398
Computerized transverse axial tomography in the newborn. 61
617309 1977
399
[Familial hydranencephaly]. 61
16211904 1977
400
[Hydranencephaly versus spelencephaly--a report of two cases (author's transl)]. 61
931594 1977
401
Antenatal diagnosis of hydranencephaly by ultrasound: correlation with ventriculography and computed tomography. 61
407259 1977
402
Congenital abnormalities in newborn calves after inoculation of pregnant cows with Akabane virus. 61
892909 1977
403
Pathology of congenital bovine epizootic arthrogryposis and hydranencephaly and its relationship to Akabane virus. 61
921638 1977
404
Hydrops amnii in sheep associated with hydranencephaly and arthrogryposis with wesselsbron disease and rift valley fever viruses as aetiological agents. 61
351506 1977
405
Bovine hydrocephalus in North Dakota: a survey and morphologic study. 61
847630 1977
406
Gyrated scalp associated with hydranencephaly in a newborn infant. 61
839350 1977
407
Congenital abnormalities in newborn lambs after infection of pregnant sheep with Akabane virus. 61
832900 1977
408
Congenital bovine epizootic arthrogryposis and hydranencephaly in Australia. Distribution of antibodies to Akabane virus in Australian Cattle after the 1974 epizootic. 61
1016149 1976
409
The histopathology of a case of hydranencephaly in a 30 week old human fetus. 61
1004801 1976
410
Bluetongue virus as a cause of hydranencephaly in cattle. 61
189265 1976
411
Hydranencephaly -- report of a case--. 61
1070412 1976
412
Sensory reinforcement of eyeblink rate in a decorticate human. 61
961732 1976
413
A pathological study on calves with arthrogryposis and hydranencephaly. 61
1266443 1976
414
Bovine congenital arthrogryphosis and hydranencephaly and human neural tube malformations in New South Wales. 61
791229 1976
415
Letter: When does hydranencephaly develop? 61
1250674 1976
416
Epizootic congenital arthrogryposis-hydranencephaly syndrome in cattle: isolation of Akabane virus from affected fetuses. 61
962588 1976
417
Letter: Akabane disease: epizootic abortion, premature birth, stillbirth and congenital arthrogryposis-hydranencephaly in cattle, sheep and goats caused by Akabane virus. 61
1222008 1975
418
[Hydranencephaly. Major cerebral lesions with normal neonatal neurologic behavior]. 61
1231676 1975
419
Letter: Hydranencephaly. 61
1165971 1975
420
Serological evidence for the association of Akabane virus with epizootic bovine congenital arthrogryposis and hydranencephaly syndromes in New South Wales. 61
1164273 1975
421
Serologic evidence for etiologic role of Akabane virus in epizootic abortion-arthrogryposis-hydranencephaly in cattle in Japan, 1972-1974. 61
1170831 1975
422
Congenital abnormality of calves with arthrogryposis and hydranencephaly in Japan in 1972-1973. 61
1121334 1975
423
Brainstem seizures in hydranencephaly. 61
4475382 1974
424
Immunoglobulins in bovine congenital hydranencephaly. 61
4458649 1974
425
Hydranencephaly following elavated hematocrit values in a newly born infant. 61
4431674 1974
426
Serum creatine phosphokinase levels in calves with arthrogryposis-hydranencephaly syndrome. 61
4450410 1974
427
Neutralizing antibody against Akabane virus in precolostral sera from calves with congenital arthrogryposis-hydranencephaly syndrome. 61
4451432 1974
428
[To the question of partial hydranencephaly (author's transl)]. 61
4526027 1974
429
[Qualitative study on hydranencephaly-fluid]. 61
4471880 1974
430
Toxoplasmosis as a cause of hydranencephaly. 61
4568341 1973
431
The origin of infantile spasms: evidence from a case of hydranencephaly. 61
4541781 1972
432
Animal model for human disease. Hydranencephaly, porencephaly, cerebral cysts, retinal dysplasia, CNS malformations. Animal model: bluetongue-vaccine-virus infection in fetal lambs. 61
4339926 1972
433
Multicystic encephalomalacia of infants and its relation to abnormal gestation and hydranencephaly. 61
5016689 1972
434
[Malformation of cerebral vessels and abnormalities of the brain. Study of hydranencephaly and alobar holoprosencephaly by cerebral angiography]. 61
5063788 1972
435
An outbreak of arthrogryposis and hydranencephaly syndrome affecting calves in Israel: a retrospective epidemiological study. 61
4374052 1972
436
Neurocranium and mandibular condyle in a case of hydranencephaly. 61
4258587 1971
437
[Congenital hydranencephaly]. 61
5159221 1971
438
[Hydranencephaly]. 61
5170532 1971
439
Experimental viral-induced congenital encephalopathies. I. Pathology of hydranencephaly and porencephaly caused by bluetongue vaccine virus. 61
5095319 1971
440
Ultrasonics in hydranencephaly in the presence of an intact falx cerebri. 61
5138233 1971
441
[Embryopathia toxoplasmotica? (Child with anophthalmos, complicated microphthalmos and hydranencephaly, the mother having anti-Lea and toxoplasmosis)]. 61
5108535 1971
442
Hydranencephaly of calves associated with natural bluetongue virus infection. 61
4325254 1971
443
The morphogenesis of hydranencephaly. 61
5101675 1971
444
Studies on the amino acid pattern of cerebrospinal fluid in a case of hydranencephaly before and after shunt operation. 61
5171360 1971
445
Eye findings in hydranencephaly. 61
5089748 1971
446
[Hydranencephaly: clinical and physiopathological study]. 61
5518760 1970
447
Hydranencephaly of postnatal origin. Case rort. 61
5309764 1970
448
Serologic evidence of an etiologic role for bluetongue virus in hydranencephaly of calves. 61
4314885 1970
449
Picture of the month. Hydranencephaly. 61
5410561 1970
450
Hydranencephaly presenting as subdural hematomas in an infant: a case report. 61
5411535 1970
451
[Multiple cystic hydranencephaly (report of 4 cases)]. 61
5309592 1969
452
Hydranencephaly in twins. 61
5254293 1969
453
"Hydranencephaly". A case report with autopsy findings in a 7-year-old girl. 61
5783419 1969
454
[Multiple malformative ocular anomalies associated with hydranencephaly]. 61
4990127 1969
455
Cerebral angiography in hydranencephaly with report of three cases. 61
5786075 1969
456
Chronic decerebrate state in infancy. Neurologic observations in long surviving cases of hydranencephaly. 61
4972347 1968
457
[The hydranencephaly. Contribution to the formal and causal pathogenesis]. 61
5303199 1968
458
"Infantile hydranencephaly"--a report of five cases of infarction of both cerebral hemispheres in infancy. 61
6075814 1967
459
[Autopsy case of hydranencephaly]. 61
5630706 1967
460
[Hydranencephaly and pseudohydranencephaly. 2 case reports]. 61
5609619 1967
461
[Apropos of the etiology of hydranencephaly]. 61
5610315 1967
462
[Hydranencephaly and internal hydrocephalus in the light of comparative pathomorphologic studies]. 61
6046259 1967
463
THE NEONATAL HAND-MOUTH REFLEX ITS PERSISTENCE IN A CASE OF HYDRANENCEPHALY. 61
14239689 1964
464
[ON THE DISEASE PICTURE OF HYDRANENCEPHALY. (CLINICAL OBSERVATIONS)]. 61
14337214 1964
465
[HYDRANENCEPHALY]. 61
14297253 1964
466
MID-LINE CLEFT LIP AND PALATE WITH HYDRANENCEPHALY AND MICROCEPHALY. 61
14116025 1964
467
[HYDRANENCEPHALY OF INFECTIOUS ORIGIN]. 61
14109668 1963
468
Hydranencephaly. A case report. 61
13863085 1962
469
[Hydranencephaly]. 61
14039903 1962
470
[On hydranencephaly]. 61
13886611 1962
471
[Apropos of a case of partial hydranencephaly of toxoplasmic origin]. 61
14000047 1962
472
Hydranencephaly: plain film findings. 61
13689941 1961
473
Ocular signs associated with hydranencephaly. 61
13714291 1961
474
[On a case of hydranencephaly]. 61
13707817 1960
475
[On the concept and diagnosis of hydranencephaly]. 61
14447977 1960
476
[The morphology and cause of hydranencephaly]. 61
14435653 1960
477
[Radiological aspects of hydranencephaly. Description of 2 cases]. 61
13808366 1959
478
Hydranencephaly and allied disorders: a study of cerebral defect in Chinese children. 61
14425055 1959
479
Transillumination of the infant head demonstrated by a case of hydranencephaly. 61
13580474 1958
480
Hydranencephaly (hydrencephaly). 61
13545875 1958
481
Hydranencephaly, with emphasis on a simple diagnostic procedure. 61
13524912 1958
482
Hydranencephaly; with report of a case. 61
13502813 1957
483
The value of transillumination in the diagnosis of hydranencephaly. 61
13377282 1957
484
Hydranencephaly with univentricular telencephalic malformation; general comments, with anatomical and clinical observations on three cases. 61
13437674 1957
485
Hydranencephaly: observations on transillumination of the head of infants. 61
13371973 1956
486
Hydranencephaly. 61
13328157 1956
487
[Hydrocephalus or hydranencephaly; value of transillumination of the cranium in differential diagnosis; anatomo-clinical study of two cases]. 61
13315047 1955
488
Hydranencephaly. 61
14386025 1955
489
Hydranencephaly. 61
14370380 1955
490
[A case of hydranencephaly with clinical diagnosis in vivo]. 61
13125097 1953
491
Angiography in a case of hydranencephaly. 61
13053369 1953
492
Hydranencephaly. 61
12996027 1953
493
[Pathogenesis of hydrocephalus and beginning hydranencephaly; pathology of the cerebrospinal fluid drainage system]. 61
13010347 1952
494
Hydranencephaly; report of a case. 61
14938769 1952
495
Hydranencephaly; clinical diagnosis; presentation of 7 cases. 61
14780790 1950

Variations for Hydranencephaly

ClinVar genetic disease variations for Hydranencephaly:

6 (showing 1, show less) ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 WDR81 NM_001163673.1(WDR81):c.59-4576G>ASNV Pathogenic/Likely pathogenic 183290 rs730882206 17:1629098-1629098 17:1725804-1725804

Expression for Hydranencephaly

Search GEO for disease gene expression data for Hydranencephaly.

Pathways for Hydranencephaly

Pathways related to Hydranencephaly according to GeneCards Suite gene sharing:

(showing 2, show less)
# Super pathways Score Top Affiliating Genes
1 11.75 TUBG1 TUBA1A PAFAH1B1 CEP55
2
Show member pathways
10.83 TUBG1 TUBB2B TUBA1A

GO Terms for Hydranencephaly

Cellular components related to Hydranencephaly according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum-Golgi intermediate compartment GO:0005793 9.33 SLC35C2 SERPINH1 KDELR1
2 cytoplasmic microtubule GO:0005881 9.13 TUBG1 TUBA1A PAFAH1B1
3 microtubule GO:0005874 9.02 TUBG1 TUBB2B TUBA1A PAFAH1B1 NDE1

Biological processes related to Hydranencephaly according to GeneCards Suite gene sharing:

(showing 15, show less)
# Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.92 SLC49A3 SLC35E1 SLC35B1 FLVCR2 FLVCR1
2 cell division GO:0051301 9.85 TUBA1A PAFAH1B1 NDE1 CEP55
3 G2/M transition of mitotic cell cycle GO:0000086 9.73 TUBG1 TUBA1A PAFAH1B1 NDE1
4 mitotic cell cycle GO:0000278 9.71 TUBG1 TUBB2B TUBA1A
5 neuron migration GO:0001764 9.71 TUBB2B PAFAH1B1 NDE1 ARX
6 microtubule cytoskeleton organization GO:0000226 9.67 TUBG1 TUBB2B TUBA1A PAFAH1B1
7 neuroblast proliferation GO:0007405 9.51 PAFAH1B1 NDE1
8 microtubule nucleation GO:0007020 9.49 TUBG1 NDE1
9 vesicle transport along microtubule GO:0047496 9.48 PAFAH1B1 NDE1
10 microtubule organizing center organization GO:0031023 9.46 PAFAH1B1 NDE1
11 ciliary basal body-plasma membrane docking GO:0097711 9.46 TUBG1 TUBA1A PAFAH1B1 NDE1
12 heme export GO:0097037 9.32 FLVCR2 FLVCR1
13 UDP-glucose transmembrane transport GO:0015786 9.26 SLC35C2 SLC35B1
14 regulation of G2/M transition of mitotic cell cycle GO:0010389 9.26 TUBG1 TUBA1A PAFAH1B1 NDE1
15 microtubule-based process GO:0007017 8.92 TUBG1 TUBB2B TUBA1A PAFAH1B1

Molecular functions related to Hydranencephaly according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 9.13 TUBG1 TUBB2B TUBA1A
2 heme transporter activity GO:0015232 8.62 FLVCR2 FLVCR1

Sources for Hydranencephaly

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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