MCID: HYD006
MIFTS: 66

Hydrocephalus

Categories: Bone diseases, Fetal diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Hydrocephalus

MalaCards integrated aliases for Hydrocephalus:

Name: Hydrocephalus 12 74 53 29 54 6 42 43 15 71 32
Hydrocephalus, Nonsyndromic, Autosomal Recessive 12 39
Hydrocephalus Adverse Event 71
Hydrocephalus, X-Linked 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10908
MeSH 43 D006849
NCIt 49 C3111
SNOMED-CT 67 230745008
ICD10 32 G91 G91.9 G94.2
UMLS 71 C0020255 C1963137

Summaries for Hydrocephalus

NINDS : 53 Hydrocephalus is a condition in which the primary characteristic is excessive accumulation of cerebrospinal fluid (CSF) -- the clear fluid that surrounds the brain and spinal cord. This excessive accumulation results in an abnormal dilation of the spaces in the brain called ventricles. This dilation causes potentially harmful pressure on the tissues of the brain. Hydrocephalus may be congenital or acquired. Congenital hydrocephalus is present at birth and may be caused by genetic abnormalities or developmental disorders such as spina bifida and encephalocele.  Acquired hydrocephalus develops at the time of birth or at some point afterward and can affect individuals of all ages.  For example, hydrocephalus ex-vacuo occurs when there is damage to the brain caused by stroke or traumatic injury.  Normal pressure hydrocephalus occurs most often among the elderly. It may result from a subarachnoid hemorrhage, head trauma, infection, tumor, or complications of surgery, although many people develop normal pressure hydrocephalus without an obvious cause. Symptoms of hydrocephalus vary with age, disease progression, and individual differences in tolerance to CSF. In infancy, the most obvious indication of hydrocephalus is often the rapid increase in head circumference or an unusually large head size. In older children and adults, symptoms may include headache followed by vomiting, nausea, papilledema (swelling of the optic disk, which is part of the optic nerve), downward deviation of the eyes (called "sunsetting"), problems with balance, poor coordination, gait disturbance, urinary incontinence, slowing or loss of development (in children), lethargy, drowsiness, irritability, or other changes in personality or cognition, including memory loss. Hydrocephalus is diagnosed through clinical neurological evaluation and by using cranial imaging techniques such as ultrasonography, computer tomography (CT), magnetic resonance imaging (MRI), or pressure-monitoring techniques.

MalaCards based summary : Hydrocephalus, also known as hydrocephalus, nonsyndromic, autosomal recessive, is related to congenital hydrocephalus and megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1, and has symptoms including seizures, tremor and back pain. An important gene associated with Hydrocephalus is FGFR2 (Fibroblast Growth Factor Receptor 2), and among its related pathways/superpathways are PI3K-Akt signaling pathway and NFAT and Cardiac Hypertrophy. The drugs Propofol and Dexmedetomidine have been mentioned in the context of this disorder. Affiliated tissues include Brain, and related phenotypes are growth/size/body region and behavior/neurological

Disease Ontology : 12 A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.

MedlinePlus : 42 Hydrocephalus is the buildup of too much cerebrospinal fluid in the brain. Normally, this fluid cushions your brain. When you have too much, though, it puts harmful pressure on your brain. Hydrocephalus can be congenital, or present at birth. Causes include genetic problems and problems with how the fetus develops. An unusually large head is the main sign of congenital hydrocephalus. Hydrocephalus can also happen after birth. This is called acquired hydrocephalus. It can occur at any age. Causes can include head injuries, strokes, infections, tumors, and bleeding in the brain. Symptoms include Headache Vomiting and nausea Blurry vision Balance problems Bladder control problems Thinking and memory problems Hydrocephalus can permanently damage the brain, causing problems with physical and mental development. If untreated, it is usually fatal. With treatment, many people lead normal lives with few limitations. Treatment usually involves surgery to insert a shunt. A shunt is a flexible but sturdy plastic tube. The shunt moves the cerebrospinal fluid to another area of the body where it can be absorbed. Medicine and rehabilitation therapy can also help. NIH: National Institute of Neurological Disorders and Stroke

Wikipedia : 74 Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the... more...

Related Diseases for Hydrocephalus

Diseases in the Hydrocephalus family:

Hydrocephalus, Autosomal Dominant Hydrocephalus, Congenital, 1
Hydrocephalus Due to Congenital Stenosis of Aqueduct of Sylvius Congenital Hydrocephalus
Hydrocephalus Autosomal Recessive

Diseases related to Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1278, show less)
# Related Disease Score Top Affiliating Genes
1 congenital hydrocephalus 35.4 TRIM71 MPDZ L1CAM CCDC88C
2 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1 35.2 PIK3R2 CCND2 AKT3
3 obstructive hydrocephalus 34.8 ZIC3 MPDZ FOXJ1
4 vacterl association with hydrocephalus 34.8 PTEN FANCB
5 congenital communicating hydrocephalus 34.6 TRIM71 MPDZ
6 dandy-walker syndrome 34.4 MPDZ KIAA1109 FOXC1 DPH1 CCDC88C
7 vacterl with hydrocephalus 34.3 PTEN FANCB
8 megalencephaly-capillary malformation-polymicrogyria syndrome 33.3 PIK3R2 AKT3
9 vacterl association with hydrocephaly, x-linked 33.1 ZIC3 FANCB
10 cowden syndrome 1 32.1 PTEN PIK3R2 AKT3
11 megalencephaly 31.5 PIK3R2 CCND2 AKT3
12 polymicrogyria 31.4 PIK3R2 CCND2 AKT3
13 vacterl association 31.2 ZIC3 PTEN FANCB
14 microcephaly 31.0 WDR81 PTEN L1CAM FOXC1 FGFR3 ARFGEF2
15 syndromic craniosynostosis 30.8 FGFR3 FGFR2
16 proteus syndrome 30.5 PTEN PIK3R2 FGFR3 AKT3
17 plagiocephaly 30.5 FGFR3 FGFR2
18 cerebral degeneration 30.4 ZIC3 L1CAM HYDIN FOXJ1
19 fgfr craniosynostosis syndromes 30.3 FGFR3 FGFR2
20 normal pressure hydrocephalus 12.8
21 hydrocephalus, congenital, 1 12.7
22 hydrocephalus, congenital, 2, with or without brain or eye anomalies 12.6
23 hydrocephalus due to congenital stenosis of aqueduct of sylvius 12.6
24 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2 12.5
25 vacterl association, x-linked, with or without hydrocephalus 12.5
26 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 12.5
27 hydrocephalus, congenital, 3, with brain anomalies 12.5
28 communicating hydrocephalus 12.5
29 hydrocephalus, endocardial fibroelastosis, and cataracts 12.5
30 thoracic dysplasia-hydrocephalus syndrome 12.5
31 hydrocephalus, congenital communicating, 1 12.5
32 hydrocephalus obesity hypogonadism 12.5
33 hydrocephalus, normal-pressure, 1 12.4
34 hydrocephalus with cerebellar agenesis 12.4
35 hydrocephalus, tall stature, joint laxity, and kyphoscoliosis 12.4
36 hydrocephalus with stenosis of the aqueduct of sylvius 12.4
37 hydrocephalus, autosomal dominant 12.4
38 hydrocephalus, sprengel anomaly, and costovertebral dysplasia 12.3
39 masa syndrome 12.3
40 hydrocephalus with associated malformations 12.3
41 tremor, hereditary essential, and idiopathic normal pressure hydrocephalus 12.2
42 isolated dandy-walker malformation without hydrocephalus 12.2
43 isolated dandy-walker malformation with hydrocephalus 12.2
44 osteochondrodysplasia, rhizomelic, with callosal agenesis, thrombocytopenia, hydrocephalus, and hypertension 12.2
45 hydrocephalus skeletal anomalies 12.2
46 walker-warburg syndrome 12.1
47 hydrocephalus autosomal recessive 12.0
48 craniosynostosis-hydrocephalus-arnold-chiari malformation type i-radioulnar synostosis syndrome 12.0
49 port-wine nevi-mega cisterna magna-hydrocephalus syndrome 12.0
50 daentl towsend siegel syndrome 12.0
51 braddock jones superneau syndrome 12.0
52 cole-carpenter syndrome 1 12.0
53 cole-carpenter syndrome 12.0
54 beemer lethal malformation syndrome 12.0
55 neural tube defects 11.9
56 chudley-mccullough syndrome 11.9
57 aase-smith syndrome i 11.8
58 myelomeningocele 11.8
59 chromosome 8q12.1-q21.2 deletion syndrome 11.7
60 papilloma of choroid plexus 11.7
61 hydranencephaly 11.5
62 mucopolysaccharidosis, type ii 11.5
63 muscular dystrophy-dystroglycanopathy , type a, 1 11.5
64 schizencephaly 11.5
65 pettigrew syndrome 11.5
66 chiari malformation 11.5
67 achondroplasia 11.5
68 congenital toxoplasmosis 11.5
69 melanosis, neurocutaneous 11.4
70 fanconi anemia, complementation group b 11.4
71 subependymal giant cell astrocytoma 11.4
72 mucopolysaccharidosis, type vi 11.4
73 vater/vacterl association 11.4
74 plasminogen deficiency, type i 11.4
75 otopalatodigital syndrome, type ii 11.4
76 ciliary dyskinesia, primary, 43 11.4
77 syringomyelia, noncommunicating isolated 11.4
78 chiari malformation type ii 11.4
79 baker vinters syndrome 11.4
80 faye-petersen-ward-carey syndrome 11.4
81 kozlowski brown hardwick syndrome 11.4
82 palmer pagon syndrome 11.4
83 schwartz cohen-addad lambert syndrome 11.4
84 vacterl hydrocephaly 11.4
85 craniosynostosis 11.4
86 encephalocele 11.3
87 cellular ependymoma 11.3
88 meningocele 11.3
89 porencephaly 11.3
90 primary ciliary dyskinesia 11.3
91 hydromyelia 11.3
92 hemangioblastoma 11.3
93 fanconi anemia, complementation group a 11.3
94 corpus callosum, agenesis of 11.3
95 meningoencephalocele 11.3
96 syringohydromyelia 11.3
97 pineocytoma 11.3
98 alexander disease 11.3
99 bobble-head doll syndrome 11.3
100 colpocephaly 11.3
101 vein of galen aneurysm 11.3
102 hajdu-cheney syndrome 11.3
103 multiple sulfatase deficiency 11.3
104 ring chromosome 6 11.3
105 congenital plasminogen deficiency 11.3
106 hydrolethalus syndrome 1 11.3
107 isotretinoin embryopathy-like syndrome 11.3
108 mannosidosis, alpha b, lysosomal 11.3
109 marden-walker syndrome 11.3
110 mental retardation, buenos aires type 11.3
111 9q22.3 microdeletion 11.3
112 crouzon syndrome with acanthosis nigricans 11.2
113 cole-carpenter syndrome 2 11.2
114 scheie syndrome 11.1
115 colloid cysts of third ventricle 11.1
116 lissencephaly 5 11.1
117 ciliary dyskinesia, primary, 42 11.1
118 choroid plexus cancer 11.1
119 diencephalic syndrome 11.1
120 cennamo gangemi syndrome 11.1
121 spina bifida cystica 11.1
122 spina bifida aperta 11.0
123 myelocystocele 11.0
124 amyloidosis, hereditary, transthyretin-related 11.0
125 greig cephalopolysyndactyly syndrome 11.0
126 craniofacial dyssynostosis with short stature 11.0
127 craniotelencephalic dysplasia 11.0
128 dandy-walker malformation with postaxial polydactyly 11.0
129 mucopolysaccharidosis, type vii 11.0
130 muscular dystrophy-dystroglycanopathy , type a, 3 11.0
131 omphalocele-cleft palate syndrome, lethal 11.0
132 canavan disease 11.0
133 mend syndrome 11.0
134 chromosome 2q37 deletion syndrome 11.0
135 microhydranencephaly 11.0
136 encephalocraniocutaneous lipomatosis 11.0
137 brain malformations with or without urinary tract defects 11.0
138 craniofacial anomalies and anterior segment dysgenesis syndrome 11.0
139 brain abnormalities, neurodegeneration, and dysosteosclerosis 11.0
140 coenurosis 11.0
141 early congenital syphilis 11.0
142 ankyloblepharon filiforme imperforate anus 11.0
143 congenital laryngeal palsy 11.0
144 fetal retinoid syndrome 11.0
145 macrocephaly-short stature-paraplegia syndrome 11.0
146 muscle eye brain disease 11.0
147 rosette-forming glioneuronal tumor 11.0
148 warfarin syndrome 11.0
149 nonsyndromic holoprosencephaly 11.0
150 nevus, epidermal 10.8 PTEN PIK3R2 FGFR3 FGFR2 AKT3
151 intracranial hypertension 10.8
152 meningitis 10.7
153 hypomelanosis of ito 10.7 PLOD1 ARFGEF2 AKT3
154 hemifacial hyperplasia 10.7 FGFR3 FGFR2
155 blake pouch cyst 10.6
156 tuberculous meningitis 10.6
157 ocular motor apraxia 10.5
158 testicular spermatocytic seminoma 10.5 FGFR3 FGFR2
159 syringomyelia 10.5
160 cerebral atrophy 10.5
161 posterior meningocele 10.5
162 ataxia and polyneuropathy, adult-onset 10.5
163 hypertelorism, microtia, facial clefting syndrome 10.5 FGFR3 FGFR2
164 dementia 10.5
165 head injury 10.5
166 aneurysm 10.4
167 cysticercosis 10.4
168 arachnoid cysts, intracranial 10.4
169 headache 10.4
170 arteriovenous malformation 10.4
171 alzheimer disease 10.4
172 papilledema 10.4
173 traumatic brain injury 10.4
174 cerebral palsy 10.4
175 encephalopathy 10.4
176 spinal arachnoiditis 10.4
177 arachnoiditis 10.4
178 neurilemmoma 10.4
179 cerebrovascular disease 10.4
180 paraplegia 10.3
181 toxoplasmosis 10.3
182 meningoencephalitis 10.3
183 acoustic neuroma 10.3
184 squamous cell papilloma 10.3
185 papilloma 10.3
186 vascular dementia 10.3
187 brain injury 10.3
188 yemenite deaf-blind hypopigmentation syndrome 10.3
189 mumps 10.3
190 bacterial meningitis 10.3
191 apraxia 10.3
192 cerebral aneurysms 10.3
193 astrocytoma 10.3
194 encephalitis 10.3
195 spasticity 10.3
196 holoprosencephaly 10.3
197 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.3
198 brain edema 10.3
199 glioma 10.3
200 seizure disorder 10.3
201 glial tumor 10.3
202 benign ependymoma 10.2
203 pathologic nystagmus 10.2
204 luteoma 10.2 FGFR3 FGFR2
205 sarcoidosis 1 10.2
206 intracranial hypertension, idiopathic 10.2
207 neurofibromatosis 10.2
208 47,xyy 10.2
209 tremor 10.2
210 macrocephaly/megalencephaly syndrome, autosomal recessive 10.2
211 mutism 10.2
212 strabismus 10.2
213 supranuclear palsy, progressive, 1 10.2
214 mechanical strabismus 10.2
215 polydactyly 10.2
216 neurosarcoidosis 10.2
217 vascular disease 10.2
218 mammary paget's disease 10.2
219 3-methylglutaconic aciduria, type iii 10.2
220 gait apraxia 10.2
221 polymicrogyria with or without vascular-type ehlers-danlos syndrome 10.2
222 visual epilepsy 10.2
223 precocious puberty 10.2
224 hypotonia 10.2
225 aphasia 10.1
226 intracranial aneurysm 10.1
227 amenorrhea 10.1
228 teratoma 10.1
229 akinetic mutism 10.1
230 medulloblastoma 10.1
231 meningioma, radiation-induced 10.1
232 meningioma, familial 10.1
233 thrombosis 10.1
234 spinal meningioma 10.1
235 aseptic meningitis 10.1
236 tuberous sclerosis 10.1
237 epilepsy 10.1
238 secretory meningioma 10.1
239 lymphoplasmacyte-rich meningioma 10.1
240 diabetes insipidus 10.1
241 cryptococcal meningitis 10.1
242 hemiplegia 10.1
243 lupus erythematosus 10.1
244 cleft lip 10.1
245 otitis media 10.1
246 craniopharyngioma 10.1
247 intracranial hypotension 10.1
248 binswanger's disease 10.1
249 overgrowth syndrome 10.1
250 anencephaly 10.1
251 frontotemporal dementia 10.1
252 chorea, childhood-onset, with psychomotor retardation 10.1
253 sleep apnea 10.1
254 sensorineural hearing loss 10.1
255 chronic meningitis 10.1
256 amnestic disorder 10.1
257 choreatic disease 10.1
258 neuroma 10.1
259 glioblastoma multiforme 10.1
260 adenoma 10.1
261 subcortical arteriosclerotic encephalopathy 10.1
262 chiari malformation type i 10.1
263 systemic lupus erythematosus 10.1
264 parkinson disease, late-onset 10.1
265 alacrima, achalasia, and mental retardation syndrome 10.1
266 guillain-barre syndrome 10.1
267 status epilepticus 10.1
268 pituitary adenoma 10.1
269 intracranial cysts 10.1
270 hypertelorism 10.0
271 hypervitaminosis a 10.0
272 branchiootic syndrome 1 10.0
273 low compliance bladder 10.0
274 lymphocytic choriomeningitis 10.0
275 periventricular leukomalacia 10.0
276 hemangioma 10.0
277 mature teratoma 10.0
278 juvenile pilocytic astrocytoma 10.0
279 vasculitis 10.0
280 learning disability 10.0
281 hypertensive encephalopathy 10.0
282 muscular dystrophy 10.0
283 pik3ca-related segmental overgrowth 10.0
284 cerebrospinal fluid leak 10.0
285 cleft lip/palate 10.0
286 huntington disease 10.0
287 trigeminal neuralgia 10.0
288 immune deficiency disease 10.0
289 mucopolysaccharidosis-plus syndrome 10.0
290 scoliosis 10.0
291 osteopetrosis 10.0
292 thrombocytopenia 10.0
293 arteriosclerosis 10.0
294 exophthalmos 10.0
295 hypopituitarism 10.0
296 spastic paraparesis 10.0
297 spinal cord injury 10.0
298 cleft palate, isolated 10.0
299 hirschsprung disease 1 10.0
300 lipomatosis, multiple 10.0
301 hemophilia a 10.0
302 corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia 10.0
303 lissencephaly 10.0
304 benign teratoma 10.0
305 pleomorphic lipoma 10.0
306 cortical blindness 10.0
307 synostosis 10.0
308 gaucher's disease 10.0
309 cystic teratoma 10.0
310 lateral sinus thrombosis 10.0
311 myotonic dystrophy 10.0
312 48,xyyy 10.0
313 chromosomal triplication 10.0
314 ciliopathy 10.0
315 arteriovenous malformations of the brain 10.0
316 pituitary adenoma, prolactin-secreting 10.0
317 intraocular pressure quantitative trait locus 10.0
318 muscular dystrophy, congenital, lmna-related 10.0
319 listeria meningitis 10.0
320 neurogenic bladder 10.0
321 syphilis 10.0
322 movement disease 10.0
323 herpes simplex 10.0
324 rubella 10.0
325 hypereosinophilic syndrome 10.0
326 hemophilia 10.0
327 dwarfism 10.0
328 neonatal meningitis 10.0
329 occipital encephalocele 10.0
330 pfeiffer syndrome 9.9
331 migraine with or without aura 1 9.9
332 obsessive-compulsive disorder 9.9
333 schizophrenia 9.9
334 down syndrome 9.9
335 tuberous sclerosis 1 9.9
336 enterocolitis 9.9
337 gaucher disease, type i 9.9
338 kearns-sayre syndrome 9.9
339 brittle bone disorder 9.9
340 autosomal recessive disease 9.9
341 ptosis 9.9
342 microphthalmia 9.9
343 respiratory failure 9.9
344 brain compression 9.9
345 oligohydramnios 9.9
346 quadriplegia 9.9
347 eclampsia 9.9
348 polyneuropathy 9.9
349 constipation 9.9
350 histiocytosis 9.9
351 cranial nerve palsy 9.9
352 infertility 9.9
353 conjunctivitis 9.9
354 peritonitis 9.9
355 nervous system disease 9.9
356 perinatal necrotizing enterocolitis 9.9
357 chorioretinitis 9.9
358 diabetes mellitus 9.9
359 hydrocele 9.9
360 choroid plexus cyst 9.9
361 ligneous conjunctivitis 9.9
362 x-linked complicated spastic paraplegia type 1 9.9
363 myoclonus 9.9
364 rhombencephalosynapsis 9.9
365 alcohol dependence 9.9
366 crouzon syndrome 9.9
367 attention deficit-hyperactivity disorder 9.9
368 neurofibromatosis, type i 9.9
369 rheumatoid arthritis 9.9
370 thrombophilia due to thrombin defect 9.9
371 tracheoesophageal fistula with or without esophageal atresia 9.9
372 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
373 hydrops fetalis, nonimmune 9.9
374 ciliary dyskinesia, primary, 1 9.9
375 abnormal hair, joint laxity, and developmental delay 9.9
376 corpus callosum, partial agenesis of, x-linked 9.9
377 patent ductus arteriosus 1 9.9
378 alkuraya-kucinskas syndrome 9.9
379 brachydactyly 9.9
380 cerebellar hypoplasia 9.9
381 siderosis 9.9
382 eosinophilic meningitis 9.9
383 pre-eclampsia 9.9
384 sarcoma 9.9
385 male infertility 9.9
386 facial paralysis 9.9
387 central nervous system tuberculosis 9.9
388 heart septal defect 9.9
389 germinoma 9.9
390 agnosia 9.9
391 spindle cell sarcoma 9.9
392 situs inversus 9.9
393 cataract 9.9
394 arthritis 9.9
395 mucormycosis 9.9
396 polyhydramnios 9.9
397 pulmonary embolism 9.9
398 corticobasal degeneration 9.9
399 growth hormone deficiency 9.9
400 syncope 9.9
401 cerebellar malformation 9.9
402 superficial siderosis 9.9
403 congenital amyoplasia 9.9
404 pik3ca-related overgrowth syndrome 9.9
405 apert syndrome 9.8
406 cerebral amyloid angiopathy, cst3-related 9.8
407 autoimmune disease 9.8
408 gastroesophageal reflux 9.8
409 epidermoid cysts 9.8
410 noonan syndrome 1 9.8
411 torticollis 9.8
412 varicose veins 9.8
413 joubert syndrome 1 9.8
414 cryptorchidism, unilateral or bilateral 9.8
415 langerhans cell histiocytosis 9.8
416 west syndrome 9.8
417 pulmonary hypertension 9.8
418 exanthem 9.8
419 cardiac arrest 9.8
420 inguinal hernia 9.8
421 mastoiditis 9.8
422 bone disease 9.8
423 asymptomatic neurosyphilis 9.8
424 monocular esotropia 9.8
425 suppression amblyopia 9.8
426 amblyopia 9.8
427 leukodystrophy 9.8
428 malignant hypertension 9.8
429 hydronephrosis 9.8
430 keratomalacia 9.8
431 alternating exotropia 9.8
432 exotropia 9.8
433 listeriosis 9.8
434 clubfoot 9.8
435 cryptococcosis 9.8
436 hemosiderosis 9.8
437 coccidioidomycosis 9.8
438 alcohol use disorder 9.8
439 hypogonadism 9.8
440 spondylosis 9.8
441 hereditary spastic paraplegia 9.8
442 glomerulonephritis 9.8
443 purpura 9.8
444 brain stem infarction 9.8
445 hyperglycemia 9.8
446 brain stem glioma 9.8
447 myopathy 9.8
448 pituitary gland disease 9.8
449 spinal stenosis 9.8
450 b-cell lymphoma 9.8
451 measles 9.8
452 bronchiectasis 9.8
453 refractive error 9.8
454 esotropia 9.8
455 congenital zika syndrome 9.8
456 neurosyphilis 9.8
457 pseudo-turner syndrome 9.8
458 cerebral arteriosclerosis 9.8
459 dementia - subcortical 9.8
460 specific language disorder 9.8
461 pneumococcal meningitis 9.8
462 central nervous system malformation 9.8
463 lobar holoprosencephaly 9.8
464 x-linked complex spastic paraplegia 9.8
465 atrial standstill 1 9.8
466 hypercarotenemia and vitamin a deficiency, autosomal dominant 9.8
467 creutzfeldt-jakob disease 9.8
468 dementia, lewy body 9.8
469 hypercholesterolemia, familial, 1 9.8
470 multiple system atrophy 1 9.8
471 klippel-trenaunay-weber syndrome 9.8
472 hemifacial microsomia 9.8
473 retinal detachment 9.8
474 tetralogy of fallot 9.8
475 renal hypodysplasia/aplasia 1 9.8
476 adducted thumbs syndrome 9.8
477 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.8
478 baller-gerold syndrome 9.8
479 cutis marmorata telangiectatica congenita 9.8
480 diastematomyelia 9.8
481 galactosemia i 9.8
482 epilepsy, pyridoxine-dependent 9.8
483 fragile x syndrome 9.8
484 thumbs, congenital clasped 9.8
485 fryns microphthalmia syndrome 9.8
486 stroke, ischemic 9.8
487 homocysteinemia 9.8
488 glycine encephalopathy 9.8
489 propionic acidemia 9.8
490 aneurysmal bone cysts 9.8
491 major affective disorder 8 9.8
492 major affective disorder 9 9.8
493 lung cancer susceptibility 3 9.8
494 aspergillosis 9.8
495 leukemia, acute lymphoblastic 3 9.8
496 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 9.8
497 helix syndrome 9.8
498 periventricular nodular heterotopia 9.8
499 chorioamnionitis 9.8
500 vitamin b12 deficiency 9.8
501 dextro-looped transposition of the great arteries 9.8
502 viral meningitis 9.8
503 endocarditis 9.8
504 klippel-feil syndrome 9.8
505 hypospadias 9.8
506 spastic diplegia 9.8
507 cerebral arteritis 9.8
508 cardiac tamponade 9.8
509 cauda equina syndrome 9.8
510 nephrotic syndrome 9.8
511 pancytopenia 9.8
512 nephrocalcinosis 9.8
513 acute cystitis 9.8
514 neuroleptic malignant syndrome 9.8
515 hypothyroidism 9.8
516 methylmalonic acidemia 9.8
517 candidiasis 9.8
518 pneumothorax 9.8
519 atrial heart septal defect 9.8
520 optic nerve disease 9.8
521 hyperostosis 9.8
522 agammaglobulinemia 9.8
523 capillary hemangioma 9.8
524 antiphospholipid syndrome 9.8
525 myelitis 9.8
526 bipolar disorder 9.8
527 middle cerebral artery infarction 9.8
528 pleural empyema 9.8
529 tricuspid valve insufficiency 9.8
530 cavernous hemangioma 9.8
531 paget's disease of bone 9.8
532 acquired immunodeficiency syndrome 9.8
533 muscular atrophy 9.8
534 neuroblastoma 9.8
535 end stage renal disease 9.8
536 subacute delirium 9.8
537 neuromyelitis optica 9.8
538 amyloidosis 9.8
539 homocystinuria 9.8
540 neurofibroma 9.8
541 alopecia 9.8
542 cytokine deficiency 9.8
543 mollaret meningitis 9.8
544 parainfluenza virus type 3 9.8
545 pure autonomic failure 9.8
546 weber syndrome 9.8
547 back pain 9.8
548 cerebral hypoxia 9.8
549 dysphagia 9.8
550 hypoxia 9.8
551 mucopolysaccharidoses 9.8
552 pituitary tumors 9.8
553 aniridia 1 9.7
554 anisocoria 9.7
555 apnea, obstructive sleep 9.7
556 basal cell nevus syndrome 9.7
557 clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly 9.7
558 coloboma of macula 9.7
559 major affective disorder 1 9.7
560 diabetes insipidus, nephrogenic, autosomal 9.7
561 multiple sclerosis 9.7
562 factor viii deficiency 9.7
563 hand skill, relative 9.7
564 diaphragmatic hernia, congenital 9.7
565 spondylosis, cervical 9.7
566 chromosome 2q35 duplication syndrome 9.7
567 thumb deformity 9.7
568 von hippel-lindau syndrome 9.7
569 carpenter syndrome 1 9.7
570 anus, imperforate 9.7
571 cystic fibrosis 9.7
572 fanconi anemia, complementation group c 9.7
573 gaucher disease, type iiic 9.7
574 hemihyperplasia, isolated 9.7
575 holoprosencephaly 1 9.7
576 meckel syndrome, type 1 9.7
577 myopathy, congenital 9.7
578 peters-plus syndrome 9.7
579 pierre robin syndrome 9.7
580 pituitary hormone deficiency, combined, 2 9.7
581 respiratory distress syndrome in premature infants 9.7
582 insulin-like growth factor i 9.7
583 adrenoleukodystrophy 9.7
584 tubulin, beta 9.7
585 calvarial hyperostosis 9.7
586 coffin-lowry syndrome 9.7
587 focal dermal hypoplasia 9.7
588 aging 9.7
589 band heterotopia 9.7
590 wilms tumor 5 9.7
591 ossification of the posterior longitudinal ligament of spine 9.7
592 gastrointestinal stromal tumor 9.7
593 cinca syndrome 9.7
594 anxiety 9.7
595 granulomatosis with polyangiitis 9.7
596 rhabdoid tumor predisposition syndrome 1 9.7
597 lipomyelomeningocele 9.7
598 diabetes mellitus, ketosis-prone 9.7
599 lissencephaly 4 9.7
600 melanoma, cutaneous malignant 10 9.7
601 peripheral vascular disease 9.7
602 angina pectoris 9.7
603 deficiency anemia 9.7
604 distal arthrogryposis 9.7
605 dyskinetic cerebral palsy 9.7
606 diffuse large b-cell lymphoma 9.7
607 paraganglioma 9.7
608 fibroma 9.7
609 cerebellar medulloblastoma 9.7
610 brain meningioma 9.7
611 spinal disease 9.7
612 bone resorption disease 9.7
613 polycystic kidney disease 9.7
614 diffuse midline glioma, h3 k27m-mutant 9.7
615 tabes dorsalis 9.7
616 venous insufficiency 9.7
617 parotitis 9.7
618 esophageal atresia 9.7
619 rickets 9.7
620 abducens nerve disease 9.7
621 cholesteatoma of middle ear 9.7
622 brucellosis 9.7
623 enophthalmos 9.7
624 vitamin k deficiency bleeding 9.7
625 epidural abscess 9.7
626 fungal meningitis 9.7
627 allergic hypersensitivity disease 9.7
628 bronchopneumonia 9.7
629 newborn respiratory distress syndrome 9.7
630 transient global amnesia 9.7
631 uveitis 9.7
632 diarrhea 9.7
633 patent foramen ovale 9.7
634 spinal cord melanoma 9.7
635 central neurocytoma 9.7
636 echinococcosis 9.7
637 mental depression 9.7
638 ventricular septal defect 9.7
639 pineoblastoma 9.7
640 histoplasmosis 9.7
641 neuritis 9.7
642 impotence 9.7
643 melanoma 9.7
644 encephalomalacia 9.7
645 atypical teratoid rhabdoid tumor 9.7
646 keratopathy 9.7
647 thrombophilia 9.7
648 relapsing polychondritis 9.7
649 glycogen storage disease 9.7
650 pulmonary tuberculosis 9.7
651 malignant glioma 9.7
652 grade iii astrocytoma 9.7
653 oligodendroglioma 9.7
654 cerebellopontine angle tumor 9.7
655 neurilemmoma of the fifth cranial nerve 9.7
656 central nervous system lymphoma 9.7
657 central nervous system disease 9.7
658 inappropriate adh syndrome 9.7
659 sagittal sinus thrombosis 9.7
660 rhabdoid cancer 9.7
661 protein c deficiency 9.7
662 heart valve disease 9.7
663 hypertrichosis 9.7
664 rhinitis 9.7
665 dysgraphia 9.7
666 cauda equina neoplasm 9.7
667 cerebellar astrocytoma 9.7
668 myxopapillary ependymoma 9.7
669 ganglioglioma 9.7
670 demyelinating polyneuropathy 9.7
671 dystonia 9.7
672 spinal cord ependymoma 9.7
673 kidney disease 9.7
674 malignant peripheral nerve sheath tumor 9.7
675 congestive heart failure 9.7
676 double outlet right ventricle 9.7
677 connective tissue disease 9.7
678 inherited metabolic disorder 9.7
679 delusional disorder 9.7
680 tertiary syphilis 9.7
681 ileus 9.7
682 influenza 9.7
683 herpes zoster 9.7
684 chickenpox 9.7
685 neuropathy 9.7
686 speech disorder 9.7
687 scotoma 9.7
688 dextrocardia 9.7
689 hypoplastic left heart syndrome 9.7
690 hypoglycemia 9.7
691 albinism 9.7
692 isolated methylmalonic acidemia 9.7
693 absence of septum pellucidum 9.7
694 acalvaria 9.7
695 adrenomyeloneuropathy 9.7
696 anaplastic oligodendroglioma 9.7
697 cerebellar agenesis 9.7
698 congenital cytomegalovirus 9.7
699 congenital rubella 9.7
700 craniofacial microsomia 9.7
701 dextrocardia with situs inversus 9.7
702 exencephaly 9.7
703 germ cells tumors 9.7
704 gigantism 9.7
705 hemimegalencephaly 9.7
706 herpes zoster ophthalmicus 9.7
707 horseshoe kidney 9.7
708 idiopathic hypertrophic pachymeningitis 9.7
709 mosaic trisomy 9 9.7
710 phacomatosis pigmentovascularis 9.7
711 primary central nervous system lymphoma 9.7
712 subependymoma 9.7
713 syringobulbia 9.7
714 depression 9.7
715 angiomatosis 9.7
716 anoxia 9.7
717 cavernous malformation 9.7
718 cytomegalovirus infection 9.7
719 persistent vegetative state 9.7
720 angioosteohypertrophic syndrome 9.7
721 isolated craniosynostosis 9.7
722 rapidly involuting congenital hemangioma 9.7
723 inflammatory myopathy with abundant macrophages 9.7
724 neurenteric cyst 9.7
725 rare hereditary hemochromatosis 9.7
726 ring chromosome 9.7
727 igg4-related pachymeningitis 9.7
728 neonatal lupus erythematosus 9.7
729 spontaneous intracranial hypotension 9.7
730 cerebral visual impairment 9.7
731 renal dysplasia 9.7
732 rare tumor 9.7
733 alobar holoprosencephaly 9.7
734 abducens palsy 9.5
735 adult syndrome 9.5
736 amyotrophic lateral sclerosis 1 9.5
737 spondyloarthropathy 1 9.5
738 aplasia cutis congenita, nonsyndromic 9.5
739 atherosclerosis susceptibility 9.5
740 bladder cancer 9.5
741 branchiootorenal syndrome 1 9.5
742 campomelic dysplasia 9.5
743 breast cancer 9.5
744 candidiasis, familial, 1 9.5
745 carpal tunnel syndrome 9.5
746 cat eye syndrome 9.5
747 cerebral cavernous malformations 9.5
748 sotos syndrome 1 9.5
749 cleidocranial dysplasia 9.5
750 seizures, benign familial neonatal, 1 9.5
751 craniometaphyseal dysplasia, autosomal dominant 9.5
752 cri-du-chat syndrome 9.5
753 cryoglobulinemia, familial mixed 9.5
754 deafness, unilateral 9.5
755 duane retraction syndrome 1 9.5
756 dystonia 1, torsion, autosomal dominant 9.5
757 multiple endocrine neoplasia, type i 9.5
758 exudative vitreoretinopathy 1 9.5
759 coffin-siris syndrome 1 9.5
760 hair whorl 9.5
761 hemifacial spasm, familial 9.5
762 renal cell carcinoma, nonpapillary 9.5
763 endosteal hyperostosis, autosomal dominant 9.5
764 kabuki syndrome 1 9.5
765 kleeblattschaedel 9.5
766 larsen syndrome 9.5
767 lentigines 9.5
768 lenz-majewski hyperostotic dwarfism 9.5
769 meckel diverticulum 9.5
770 megalencephaly, autosomal dominant 9.5
771 macrodactyly 9.5
772 metaphyseal chondrodysplasia, schmid type 9.5
773 holoprosencephaly 2 9.5
774 nevus anemicus 9.5
775 ocular dominance 9.5
776 optic nerve hypoplasia, bilateral 9.5
777 osteogenesis imperfecta, type ii 9.5
778 osteoporosis 9.5
779 pheochromocytoma 9.5
780 pick disease of brain 9.5
781 polykaryocytosis inducer 9.5
782 raynaud disease 9.5
783 dowling-degos disease 1 9.5
784 scleroderma, familial progressive 9.5
785 shprintzen-goldberg craniosynostosis syndrome 9.5
786 septooptic dysplasia 9.5
787 spinal intradural arachnoid cysts 9.5
788 odontochondrodysplasia 9.5
789 sturge-weber syndrome 9.5
790 teeth present at birth 9.5
791 telecanthus 9.5
792 thanatophoric dysplasia, type i 9.5
793 thanatophoric dysplasia, type ii 9.5
794 thrombocytopenic purpura, autoimmune 9.5
795 thrombophilia due to activated protein c resistance 9.5
796 triiodothyronine receptor auxiliary protein 9.5
797 vesicoureteral reflux 1 9.5
798 wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome 9.5
799 acrocallosal syndrome 9.5
800 short-rib thoracic dysplasia 1 with or without polydactyly 9.5
801 autism 9.5
802 cockayne syndrome a 9.5
803 craniodiaphyseal dysplasia 9.5
804 craniosynostosis with fibular aplasia 9.5
805 mitochondrial complex iv deficiency 9.5
806 leukoencephalopathy, hereditary diffuse, with spheroids 9.5
807 duodenal atresia 9.5
808 proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome 9.5
809 endocardial fibroelastosis 9.5
810 fanconi anemia, complementation group d2 9.5
811 gastroschisis 9.5
812 gaucher disease, type ii 9.5
813 gaucher disease, type iii 9.5
814 glycogen storage disease ii 9.5
815 hemangiopericytoma, malignant 9.5
816 homocystinuria due to deficiency of n -methylenetetrahydrofolate reductase activity 9.5
817 urofacial syndrome 1 9.5
818 krabbe disease 9.5
819 epilepsy, focal, with speech disorder and with or without mental retardation 9.5
820 multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects 9.5
821 donohue syndrome 9.5
822 megalocornea 9.5
823 metachromatic leukodystrophy 9.5
824 spondylometaphyseal dysplasia, sedaghatian type 9.5
825 moyamoya disease 1 9.5
826 mucolipidosis ii alpha/beta 9.5
827 myasthenia gravis 9.5
828 opsismodysplasia 9.5
829 phenylketonuria 9.5
830 short-rib thoracic dysplasia 6 with or without polydactyly 9.5
831 pycnodysostosis 9.5
832 knobloch syndrome 1 9.5
833 rothmund-thomson syndrome, type 2 9.5
834 smith-lemli-opitz syndrome 9.5
835 sudden infant death syndrome 9.5
836 gm2-gangliosidosis, ab variant 9.5
837 tay-sachs disease 9.5
838 thymoma, familial 9.5
839 graves disease 1 9.5
840 spondylocostal dysostosis 1, autosomal recessive 9.5
841 xeroderma pigmentosum, variant type 9.5
842 opitz gbbb syndrome, type i 9.5
843 body mass index quantitative trait locus 11 9.5
844 orofaciodigital syndrome viii 9.5
845 autism x-linked 2 9.5
846 anemia, x-linked, with or without neutropenia and/or platelet abnormalities 9.5
847 wiskott-aldrich syndrome 9.5
848 arts syndrome 9.5
849 aicardi syndrome 9.5
850 opitz-kaveggia syndrome 9.5
851 incontinentia pigmenti 9.5
852 lowe oculocerebrorenal syndrome 9.5
853 muscular dystrophy, duchenne type 9.5
854 epilepsy, childhood absence 1 9.5
855 gomez-lopez-hernandez syndrome 9.5
856 autoimmune lymphoproliferative syndrome 9.5
857 body mass index quantitative trait locus 9 9.5
858 muenke syndrome 9.5
859 acromesomelic dysplasia, maroteaux type 9.5
860 astigmatism 9.5
861 body mass index quantitative trait locus 8 9.5
862 intervertebral disc disease 9.5
863 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.5
864 optic atrophy 4 9.5
865 tetralogy of fallot syndrome, autosomal recessive 9.5
866 pars planitis 9.5
867 body mass index quantitative trait locus 1 9.5
868 van der woude syndrome 2 9.5
869 anorexia nervosa 9.5
870 polymicrogyria, bilateral frontoparietal 9.5
871 bone mineral density quantitative trait locus 3 9.5
872 hurler syndrome 9.5
873 nasopharyngeal carcinoma 9.5
874 meckel syndrome, type 3 9.5
875 lissencephaly 1 9.5
876 body mass index quantitative trait locus 4 9.5
877 body mass index quantitative trait locus 10 9.5
878 mycobacterium tuberculosis 1 9.5
879 gaucher disease, perinatal lethal 9.5
880 leukemia, chronic myeloid 9.5
881 body mass index quantitative trait locus 7 9.5
882 major depressive disorder 9.5
883 ciliary dyskinesia, primary, 3 9.5
884 choanal atresia, posterior 9.5
885 aplastic anemia 9.5
886 human immunodeficiency virus type 1 9.5
887 alzheimer disease 10 9.5
888 malaria 9.5
889 bone mineral density quantitative trait locus 8 9.5
890 body mass index quantitative trait locus 12 9.5
891 sarcoidosis 3 9.5
892 body mass index quantitative trait locus 14 9.5
893 bone mineral density quantitative trait locus 15 9.5
894 odontoid hypoplasia 9.5
895 cardiomyopathy, familial hypertrophic, 20 9.5
896 microcephaly-capillary malformation syndrome 9.5
897 tumor predisposition syndrome 9.5
898 hemorrhage, intracerebral 9.5
899 leukoencephalopathy, brain calcifications, and cysts 9.5
900 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.5
901 body mass index quantitative trait locus 18 9.5
902 hyperprolactinemia 9.5
903 alzheimer disease 18 9.5
904 optic atrophy 9 9.5
905 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.5
906 joint laxity, short stature, and myopia 9.5
907 body mass index quantitative trait locus 19 9.5
908 body mass index quantitative trait locus 20 9.5
909 cortical dysplasia, complex, with other brain malformations 10 9.5
910 cebalid syndrome 9.5
911 juvenile arthritis 9.5
912 adrenal cortical carcinoma 9.5
913 streptococcus pneumonia 9.5
914 chikungunya 9.5
915 aspiration pneumonia 9.5
916 variola major 9.5
917 ross river fever 9.5
918 orofacial cleft 9.5
919 muscular dystrophy-dystroglycanopathy 9.5
920 asphyxiating thoracic dystrophy 9.5
921 oculocutaneous albinism 9.5
922 fetal alcohol syndrome 9.5
923 alcohol-related birth defect 9.5
924 anaplastic large cell lymphoma 9.5
925 atrioventricular block 9.5
926 hemidystonia 9.5
927 adrenal gland pheochromocytoma 9.5
928 spastic ataxia 9.5
929 sexual disorder 9.5
930 lymphoma 9.5
931 brain glioma 9.5
932 anosognosia 9.5
933 auditory agnosia 9.5
934 pain agnosia 9.5
935 organic acidemia 9.5
936 colitis 9.5
937 cogan syndrome 9.5
938 agraphia 9.5
939 basal ganglia calcification 9.5
940 stuttering 9.5
941 parietal foramina 9.5
942 penicillin allergy 9.5
943 purpura fulminans 9.5
944 anterior segment dysgenesis 9.5
945 griscelli syndrome 9.5
946 x-linked recessive disease 9.5
947 acromesomelic dysplasia 9.5
948 intestinal pseudo-obstruction 9.5
949 spina bifida occulta 9.5
950 myoglobinuria 9.5
951 meningococcal meningitis 9.5
952 haemophilus meningitis 9.5
953 renal hypoplasia 9.5
954 mucolipidosis 9.5
955 hypogonadotropic hypogonadism 9.5
956 col4a1-related familial vascular leukoencephalopathy 9.5
957 sparganosis 9.5
958 intracranial abscess 9.5
959 cholelithiasis 9.5
960 blepharophimosis 9.5
961 bacterial infectious disease 9.5
962 common cold 9.5
963 cystinosis 9.5
964 japanese encephalitis 9.5
965 strongyloidiasis 9.5
966 lipoid nephrosis 9.5
967 spastic hemiplegia 9.5
968 asphyxia neonatorum 9.5
969 pseudomembranous conjunctivitis 9.5
970 hypoparathyroidism 9.5
971 primary hyperparathyroidism 9.5
972 rabies 9.5
973 pituitary apoplexy 9.5
974 retinal microaneurysm 9.5
975 vertebral artery occlusion 9.5
976 tetanus 9.5
977 subdural empyema 9.5
978 pulmonary edema 9.5
979 heart disease 9.5
980 choroiditis 9.5
981 hemopericardium 9.5
982 suppurative otitis media 9.5
983 oculomotor nerve paralysis 9.5
984 streptococcal meningitis 9.5
985 lyme disease 9.5
986 iron deficiency anemia 9.5
987 leukocoria 9.5
988 pericardial effusion 9.5
989 myopia 9.5
990 sarcoid meningitis 9.5
991 optic neuritis 9.5
992 inflammatory spondylopathy 9.5
993 pica disease 9.5
994 alveolar echinococcosis 9.5
995 neutropenia 9.5
996 anisometropia 9.5
997 cough variant asthma 9.5
998 marasmus 9.5
999 hematocele of tunica vaginalis testis 9.5
1000 entropion 9.5
1001 sulfhemoglobinemia 9.5
1002 bell's palsy 9.5
1003 von willebrand's disease 9.5
1004 hepatic coma 9.5
1005 dyscalculia 9.5
1006 locked-in syndrome 9.5
1007 mucopolysaccharidosis iii 9.5
1008 lagophthalmos 9.5
1009 hereditary spherocytosis 9.5
1010 plasmodium vivax malaria 9.5
1011 severe pre-eclampsia 9.5
1012 hellp syndrome 9.5
1013 gout 9.5
1014 pure red-cell aplasia 9.5
1015 skin sarcoidosis 9.5
1016 pulmonary sarcoidosis 9.5
1017 basilar artery occlusion 9.5
1018 hyperparathyroidism 9.5
1019 obstructive jaundice 9.5
1020 achromatopsia 9.5
1021 benign paroxysmal positional nystagmus 9.5
1022 toxic shock syndrome 9.5
1023 spinal cord sarcoma 9.5
1024 renal tubular acidosis 9.5
1025 noonan syndrome with multiple lentigines 9.5
1026 generalized anxiety disorder 9.5
1027 gonadal dysgenesis 9.5
1028 neuronal ceroid lipofuscinosis 9.5
1029 niemann-pick disease 9.5
1030 foster-kennedy syndrome 9.5
1031 axenfeld-rieger syndrome 9.5
1032 ectropion 9.5
1033 hypoglycemic coma 9.5
1034 mitral valve stenosis 9.5
1035 pericarditis 9.5
1036 ossifying fibroma 9.5
1037 hepatitis c 9.5
1038 viral hepatitis 9.5
1039 endodermal sinus tumor 9.5
1040 dysostosis 9.5
1041 bardet-biedl syndrome 9.5
1042 leiomyosarcoma 9.5
1043 benign giant cell tumor 9.5
1044 hyperinsulinism 9.5
1045 exostosis 9.5
1046 ectodermal dysplasia 9.5
1047 focal epilepsy 9.5
1048 leptospirosis 9.5
1049 lateral sclerosis 9.5
1050 gastroenteritis 9.5
1051 iron metabolism disease 9.5
1052 gangliocytoma 9.5
1053 glomus tumor 9.5
1054 acromegaly 9.5
1055 retinal vascular disease 9.5
1056 kluver-bucy syndrome 9.5
1057 landau-kleffner syndrome 9.5
1058 familial nephrotic syndrome 9.5
1059 benign mesothelioma 9.5
1060 transitional cell carcinoma 9.5
1061 dysembryoplastic neuroepithelial tumor 9.5
1062 cryoglobulinemia 9.5
1063 newcastle disease 9.5
1064 cockayne syndrome 9.5
1065 cystic kidney disease 9.5
1066 adenocarcinoma 9.5
1067 germ cell cancer 9.5
1068 cystic lymphangioma 9.5
1069 multiple endocrine neoplasia 9.5
1070 lipid metabolism disorder 9.5
1071 lipomatosis 9.5
1072 progressive muscular atrophy 9.5
1073 spinal cord glioma 9.5
1074 spinal cord disease 9.5
1075 c-p angle neurinoma 9.5
1076 neurilemmomatosis 9.5
1077 demyelinating disease 9.5
1078 lipid pneumonia 9.5
1079 ischemia 9.5
1080 thymoma 9.5
1081 vaccinia 9.5
1082 gm2 gangliosidosis 9.5
1083 mood disorder 9.5
1084 mesenchymal cell neoplasm 9.5
1085 turner syndrome 9.5
1086 spinal cord intramedullary teratoma 9.5
1087 empty sella syndrome 9.5
1088 hermaphroditism 9.5
1089 intraventricular meningioma 9.5
1090 thrombophlebitis 9.5
1091 gastritis 9.5
1092 tricuspid valve stenosis 9.5
1093 intracranial thrombosis 9.5
1094 dyslexia 9.5
1095 skull base meningioma 9.5
1096 bartter disease 9.5
1097 avian influenza 9.5
1098 hypokalemia 9.5
1099 bile duct cancer 9.5
1100 endophthalmitis 9.5
1101 mongolian spot 9.5
1102 diffuse glomerulonephritis 9.5
1103 ependymoblastoma 9.5
1104 spinal cord astrocytoma 9.5
1105 prosopagnosia 9.5
1106 essential tremor 9.5
1107 pineal gland cancer 9.5
1108 middle ear disease 9.5
1109 ovarian cyst 9.5
1110 borna disease 9.5
1111 urinary tract obstruction 9.5
1112 chronic inflammatory demyelinating polyradiculoneuropathy 9.5
1113 blepharospasm 9.5
1114 anterograde amnesia 9.5
1115 testicular yolk sac tumor 9.5
1116 sleep disorder 9.5
1117 internuclear ophthalmoplegia 9.5
1118 clear cell ependymoma 9.5
1119 third cranial nerve disease 9.5
1120 peripheral nervous system disease 9.5
1121 subvalvular aortic stenosis 9.5
1122 hemolytic anemia 9.5
1123 nephrolithiasis 9.5
1124 meningeal melanocytoma 9.5
1125 gliomatosis cerebri 9.5
1126 cerebellopontine angle meningioma 9.5
1127 diffuse meningeal melanocytosis 9.5
1128 pulmonary valve stenosis 9.5
1129 progressive multifocal leukoencephalopathy 9.5
1130 viral encephalitis 9.5
1131 spondylitis 9.5
1132 juvenile rheumatoid arthritis 9.5
1133 spinal cord primitive neuroectodermal neoplasm 9.5
1134 skin tag 9.5
1135 t-cell lymphoblastic leukemia/lymphoma 9.5
1136 thyroiditis 9.5
1137 meningothelial meningioma 9.5
1138 pineal region germinoma 9.5
1139 peptic ulcer disease 9.5
1140 carotid artery occlusion 9.5
1141 myocarditis 9.5
1142 appendicitis 9.5
1143 intestinal obstruction 9.5
1144 malignant hyperthermia 9.5
1145 ulcerative colitis 9.5
1146 myeloid leukemia 9.5
1147 smallpox 9.5
1148 mitochondrial encephalomyopathy 9.5
1149 autosomal dominant polycystic kidney disease 9.5
1150 narcolepsy 9.5
1151 cholangitis 9.5
1152 otitis externa 9.5
1153 stomatitis 9.5
1154 toxocariasis 9.5
1155 radioulnar synostosis 9.5
1156 hypertropia 9.5
1157 hypotropia 9.5
1158 miliary tuberculosis 9.5
1159 dacryocystocele 9.5
1160 drug dependence 9.5
1161 heterotaxy 9.5
1162 col1a1/2 osteogenesis imperfecta 9.5
1163 cleidocranial dysplasia spectrum disorder 9.5
1164 frem1 autosomal recessive disorders 9.5
1165 irf6-related disorders 9.5
1166 spondylocostal dysostosis, autosomal recessive 9.5
1167 x-linked otopalatodigital spectrum disorders 9.5
1168 aids dementia complex 9.5
1169 anaplastic ependymoma 9.5
1170 aortic arch interruption 9.5
1171 atlanto-axial fusion 9.5
1172 branchial arch defects 9.5
1173 broken heart syndrome 9.5
1174 bronchopulmonary dysplasia 9.5
1175 charles bonnet syndrome 9.5
1176 chromosome 15q deletion 9.5
1177 chromosome 1q deletion 9.5
1178 chromosome 6q deletion 9.5
1179 chromosome 8q duplication 9.5
1180 congenital muscular dystrophy due to dystroglycanopathy 9.5
1181 congenital varicella syndrome 9.5
1182 dipsogenic diabetes insipidus 9.5
1183 distal renal tubular acidosis 9.5
1184 fetal and neonatal alloimmune thrombocytopenia 9.5
1185 foix chavany marie syndrome 9.5
1186 gangliosidosis 9.5
1187 growth retardation hydrocephaly lung hypoplasia 9.5
1188 haemophilus influenzae 9.5
1189 hemorrhagic shock and encephalopathy syndrome 9.5
1190 herpes simplex encephalitis 9.5
1191 hip subluxation 9.5
1192 human t-cell leukemia virus type 1 9.5
1193 hypothalamic obesity 9.5
1194 knobloch syndrome 9.5
1195 leukemia, t-cell, chronic 9.5
1196 lymphosarcoma 9.5
1197 macrophage activation syndrome 9.5
1198 mosaic trisomy 22 9.5
1199 myoclonus epilepsy 9.5
1200 neonatal herpes 9.5
1201 neonatal stroke 9.5
1202 ogilvie syndrome 9.5
1203 oligoastrocytoma 9.5
1204 oto-palatal-digital syndrome 9.5
1205 pachygyria 9.5
1206 periodontal ehlers-danlos syndrome 9.5
1207 phocomelia 9.5
1208 pontine hemorrhage 9.5
1209 retinochoroidal coloboma 9.5
1210 rosai-dorfman disease 9.5
1211 sacrococcygeal teratoma 9.5
1212 single ventricular heart 9.5
1213 sirenomelia 9.5
1214 skeletal dysplasias 9.5
1215 spinal shock 9.5
1216 splenomegaly 9.5
1217 superficial siderosis of the central nervous system 9.5
1218 tarlov cysts 9.5
1219 tetraploidy 9.5
1220 thunderclap headache 9.5
1221 tracheobronchomalacia 9.5
1222 transverse myelitis 9.5
1223 trisomy 22 9.5
1224 raynaud phenomenon 9.5
1225 abdominal wall defect 9.5
1226 central precocious puberty 9.5
1227 farsightedness 9.5
1228 isolated pierre robin sequence 9.5
1229 autonomic dysfunction 9.5
1230 central cord syndrome 9.5
1231 dysautonomia 9.5
1232 hemifacial spasm 9.5
1233 hypersomnia 9.5
1234 hypertonia 9.5
1235 immune-mediated encephalomyelitis 9.5
1236 meningitis and encephalitis 9.5
1237 myopathy - thyrotoxic 9.5
1238 myotonia 9.5
1239 shaken baby syndrome 9.5
1240 spinal cord infarction 9.5
1241 whiplash 9.5
1242 posttransplant acute limbic encephalitis 9.5
1243 frontal encephalocele 9.5
1244 perioral myoclonia with absences 9.5
1245 cerebrofacial arteriovenous metameric syndrome 9.5
1246 supernumerary nostril 9.5
1247 kenny-caffey syndrome 9.5
1248 low-grade astrocytoma 9.5
1249 benign peripheral nerve sheath tumor 9.5
1250 diffuse leptomeningeal melanocytosis 9.5
1251 trisomy 1q 9.5
1252 bilateral polymicrogyria 9.5
1253 midline cerebral malformation 9.5
1254 hemihyperplasia-multiple lipomatosis syndrome 9.5
1255 fowler urethral sphincter dysfunction syndrome 9.5
1256 semilobar holoprosencephaly 9.5
1257 congenital achiasma 9.5
1258 qualitative or quantitative defects of alpha-dystroglycan 9.5
1259 pseudo-meigs syndrome 9.5
1260 congenital hemangioma 9.5
1261 persistent idiopathic facial pain 9.5
1262 isolated oxycephaly 9.5
1263 argyria 9.5
1264 monosomy 9q22.3 9.5
1265 6q terminal deletion syndrome 9.5
1266 postinfectious vasculitis 9.5
1267 cobblestone lissencephaly 9.5
1268 congenital ectropion uveae 9.5
1269 functioning gonadotropic adenoma 9.5
1270 regional odontodysplasia 9.5
1271 autosomal trisomy 9.5
1272 cranial malformation 9.5
1273 congenital ectropion 9.5
1274 congenital arteriovenous fistula 9.5
1275 red cell aplasia 9.5
1276 posterior fossa malformation 9.5
1277 multiple congenital anomalies/dysmorphic syndrome-intellectual disability 9.5
1278 idiopathic syringomyelia 9.5

Graphical network of the top 20 diseases related to Hydrocephalus:



Diseases related to Hydrocephalus

Symptoms & Phenotypes for Hydrocephalus

UMLS symptoms related to Hydrocephalus:


seizures, tremor, back pain, headache, syncope, pain, chronic pain, sciatica, vertigo/dizziness, sleeplessness

MGI Mouse Phenotypes related to Hydrocephalus:

45 (showing 14, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.39 AKT3 ARFGEF2 DPH1 FANCB FGFR2 FGFR3
2 behavior/neurological MP:0005386 10.35 AKT3 CCND2 FGFR2 FGFR3 FOXJ1 HYDIN
3 cardiovascular system MP:0005385 10.34 AKT3 CCND2 FGFR2 FOXC1 FOXJ1 HYDIN
4 cellular MP:0005384 10.32 AKT3 ARFGEF2 DPH1 FANCB FGFR2 FGFR3
5 mortality/aging MP:0010768 10.31 AKT3 ARFGEF2 CCND2 DPH1 FGFR2 FGFR3
6 nervous system MP:0003631 10.21 AKT3 ARFGEF2 CCND2 DPH1 FGFR2 FGFR3
7 craniofacial MP:0005382 10.15 DPH1 FGFR2 FGFR3 FOXC1 FOXJ1 HYDIN
8 integument MP:0010771 10.09 DPH1 FGFR2 FGFR3 FOXC1 KIAA1109 L1CAM
9 digestive/alimentary MP:0005381 10.02 DPH1 FGFR2 FGFR3 FOXC1 FOXJ1 PTEN
10 reproductive system MP:0005389 10 AKT3 CCND2 FANCB FGFR2 FGFR3 FOXC1
11 respiratory system MP:0005388 9.81 DPH1 FGFR2 FGFR3 FOXC1 FOXJ1 HYDIN
12 pigmentation MP:0001186 9.72 DPH1 FGFR2 FOXC1 L1CAM PTEN
13 skeleton MP:0005390 9.65 CCND2 DPH1 FGFR2 FGFR3 FOXC1 HYDIN
14 vision/eye MP:0005391 9.36 CCND2 DPH1 FGFR2 FGFR3 FOXC1 KIAA1109

Drugs & Therapeutics for Hydrocephalus

Drugs for Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 170, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
3
Citalopram Approved Phase 4 59729-33-8 2771
4
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
5
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
6
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
7
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
8 Anesthetics Phase 4
9 Adrenergic alpha-Agonists Phase 4
10 Adrenergic Agents Phase 4
11 Anesthetics, General Phase 4
12 Analgesics, Non-Narcotic Phase 4
13 Analgesics Phase 4
14 Adrenergic Agonists Phase 4
15 Hypnotics and Sedatives Phase 4
16 Anesthetics, Inhalation Phase 4
17 Neurotransmitter Agents Phase 4
18 Pharmaceutical Solutions Phase 4
19 Anesthetics, Intravenous Phase 4
20 Anti-Arrhythmia Agents Phase 4
21 Cholinergic Agents Phase 4
22 Serotonin Receptor Agonists Phase 4
23 Muscarinic Antagonists Phase 4
24 Serotonin Uptake Inhibitors Phase 4
25 Cholinergic Antagonists Phase 4
26 Sodium Channel Blockers Phase 4
27 Platelet Aggregation Inhibitors Phase 4
28 Diuretics, Potassium Sparing Phase 4
29
Glycopyrrolate Phase 4 596-51-0 3494
30 Anesthetics, Local Phase 4
31
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
32
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
33
Rifampicin Approved Phase 3 13292-46-1 5381226 5458213
34
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
35
Indomethacin Approved, Investigational Phase 3 53-86-1 3715
36
Sodium citrate Approved, Investigational Phase 3 68-04-2
37
Caffeine Approved Phase 3 58-08-2 2519
38
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
39
Acetaminophen Approved Phase 2, Phase 3 103-90-2 1983
40
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
41
Naproxen Approved, Vet_approved Phase 2, Phase 3 22204-53-1 1302 156391
42
Guaifenesin Approved, Investigational, Vet_approved Phase 2, Phase 3 93-14-1 3516
43
Codeine Approved, Illicit Phase 2, Phase 3 76-57-3 5284371
44
Aspirin Approved, Vet_approved Phase 2, Phase 3 50-78-2 2244
45
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
46
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743