MCID: HYD006
MIFTS: 65

Hydrocephalus

Categories: Bone diseases, Fetal diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Hydrocephalus

MalaCards integrated aliases for Hydrocephalus:

Name: Hydrocephalus 12 74 53 29 54 6 42 43 15 71 32
Hydrocephalus, Nonsyndromic, Autosomal Recessive 12 39
Hydrocephalus Adverse Event 71
Hydrocephalus, X-Linked 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10908
MeSH 43 D006849
NCIt 49 C3111
ICD10 32 G91 G91.9 G94.2
UMLS 71 C0020255 C1963137

Summaries for Hydrocephalus

NINDS : 53 Hydrocephalus is a condition in which the primary characteristic is excessive accumulation of cerebrospinal fluid (CSF) -- the clear fluid that surrounds the brain and spinal cord. This excessive accumulation results in an abnormal dilation of the spaces in the brain called ventricles. This dilation causes potentially harmful pressure on the tissues of the brain. Hydrocephalus may be congenital or acquired. Congenital hydrocephalus is present at birth and may be caused by genetic abnormalities or developmental disorders such as spina bifida and encephalocele.  Acquired hydrocephalus develops at the time of birth or at some point afterward and can affect individuals of all ages.  For example, hydrocephalus ex-vacuo occurs when there is damage to the brain caused by stroke or traumatic injury.  Normal pressure hydrocephalus occurs most often among the elderly. It may result from a subarachnoid hemorrhage, head trauma, infection, tumor, or complications of surgery, although many people develop normal pressure hydrocephalus without an obvious cause. Symptoms of hydrocephalus vary with age, disease progression, and individual differences in tolerance to CSF. In infancy, the most obvious indication of hydrocephalus is often the rapid increase in head circumference or an unusually large head size. In older children and adults, symptoms may include headache followed by vomiting, nausea, papilledema (swelling of the optic disk, which is part of the optic nerve), downward deviation of the eyes (called "sunsetting"), problems with balance, poor coordination, gait disturbance, urinary incontinence, slowing or loss of development (in children), lethargy, drowsiness, irritability, or other changes in personality or cognition, including memory loss. Hydrocephalus is diagnosed through clinical neurological evaluation and by using cranial imaging techniques such as ultrasonography, computer tomography (CT), magnetic resonance imaging (MRI), or pressure-monitoring techniques.

MalaCards based summary : Hydrocephalus, also known as hydrocephalus, nonsyndromic, autosomal recessive, is related to congenital hydrocephalus and megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1, and has symptoms including seizures, tremor and back pain. An important gene associated with Hydrocephalus is FGFR2 (Fibroblast Growth Factor Receptor 2), and among its related pathways/superpathways are PI3K-Akt signaling pathway and NFAT and Cardiac Hypertrophy. The drugs Citalopram and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include Brain, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Disease Ontology : 12 A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.

MedlinePlus : 42 Hydrocephalus is the buildup of too much cerebrospinal fluid in the brain. Normally, this fluid cushions your brain. When you have too much, though, it puts harmful pressure on your brain. Hydrocephalus can be congenital, or present at birth. Causes include genetic problems and problems with how the fetus develops. An unusually large head is the main sign of congenital hydrocephalus. Hydrocephalus can also happen after birth. This is called acquired hydrocephalus. It can occur at any age. Causes can include head injuries, strokes, infections, tumors, and bleeding in the brain. Symptoms include Headache Vomiting and nausea Blurry vision Balance problems Bladder control problems Thinking and memory problems Hydrocephalus can permanently damage the brain, causing problems with physical and mental development. If untreated, it is usually fatal. With treatment, many people lead normal lives with few limitations. Treatment usually involves surgery to insert a shunt. A shunt is a flexible but sturdy plastic tube. The shunt moves the cerebrospinal fluid to another area of the body where it can be absorbed. Medicine and rehabilitation therapy can also help. NIH: National Institute of Neurological Disorders and Stroke

Wikipedia : 74 Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the... more...

Related Diseases for Hydrocephalus

Diseases in the Hydrocephalus family:

Hydrocephalus, Autosomal Dominant Hydrocephalus, Congenital, 1
Hydrocephalus Due to Congenital Stenosis of Aqueduct of Sylvius Congenital Hydrocephalus
Hydrocephalus Autosomal Recessive

Diseases related to Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1277, show less)
# Related Disease Score Top Affiliating Genes
1 congenital hydrocephalus 35.5 STK36 MPDZ L1CAM FOXC1 CCDC88C
2 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1 35.2 PIK3R2 CCND2 AKT3
3 vacterl association with hydrocephalus 34.9 PTEN FANCB
4 dandy-walker syndrome 34.4 MPDZ KIAA1109 FOXC1 DPH1 CCDC88C
5 vacterl with hydrocephalus 34.3 PTEN FANCB
6 megalencephaly-capillary malformation-polymicrogyria syndrome 33.4 PIK3R2 AKT3
7 vacterl association with hydrocephaly, x-linked 33.2 ZIC3 FANCB
8 cowden syndrome 1 32.3 PTEN PIK3R2 AKT3
9 megalencephaly 31.5 PIK3R2 CCND2 AKT3
10 polymicrogyria 31.4 PIK3R2 CCND2 AKT3
11 vacterl association 31.2 ZIC3 PTEN FANCB
12 microcephaly 31.2 WDR81 PTEN L1CAM FOXC1 FGFR3 ARFGEF2
13 syndromic craniosynostosis 30.9 FGFR3 FGFR2
14 cutis marmorata telangiectatica congenita 30.8 PIK3R2 AKT3
15 plagiocephaly 30.6 FGFR3 FGFR2
16 proteus syndrome 30.5 PTEN PIK3R2 FGFR3 AKT3
17 fgfr-related craniosynostosis syndromes 30.4 FGFR3 FGFR2
18 cerebral degeneration 30.3 ZIC3 L1CAM HYDIN
19 normal pressure hydrocephalus 12.8
20 hydrocephalus, congenital, 1 12.7
21 hydrocephalus, congenital, 2, with or without brain or eye anomalies 12.6
22 hydrocephalus due to congenital stenosis of aqueduct of sylvius 12.6
23 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2 12.5
24 megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 12.5
25 hydrocephalus, congenital, 3, with brain anomalies 12.5
26 vacterl association, x-linked, with or without hydrocephalus 12.5
27 communicating hydrocephalus 12.5
28 hydrocephalus, endocardial fibroelastosis, and cataracts 12.5
29 obstructive hydrocephalus 12.5
30 thoracic dysplasia-hydrocephalus syndrome 12.5
31 hydrocephalus obesity hypogonadism 12.4
32 hydrocephalus with cerebellar agenesis 12.4
33 hydrocephalus, tall stature, joint laxity, and kyphoscoliosis 12.4
34 hydrocephalus with stenosis of the aqueduct of sylvius 12.4
35 hydrocephalus, autosomal dominant 12.4
36 congenital communicating hydrocephalus 12.4
37 hydrocephalus, sprengel anomaly, and costovertebral dysplasia 12.3
38 masa syndrome 12.3
39 hydrocephalus with associated malformations 12.3
40 hydrocephalus, normal-pressure, 1 12.2
41 tremor, hereditary essential, and idiopathic normal pressure hydrocephalus 12.2
42 hydrocephalus, congenital communicating, 1 12.2
43 isolated dandy-walker malformation without hydrocephalus 12.2
44 isolated dandy-walker malformation with hydrocephalus 12.2
45 osteochondrodysplasia, rhizomelic, with callosal agenesis, thrombocytopenia, hydrocephalus, and hypertension 12.2
46 hydrocephalus skeletal anomalies 12.2
47 walker-warburg syndrome 12.1
48 hydrocephalus autosomal recessive 12.0
49 craniosynostosis-hydrocephalus-arnold-chiari malformation type i-radioulnar synostosis syndrome 12.0
50 port-wine nevi-mega cisterna magna-hydrocephalus syndrome 12.0
51 daentl towsend siegel syndrome 12.0
52 braddock jones superneau syndrome 12.0
53 cole-carpenter syndrome 1 12.0
54 cole-carpenter syndrome 12.0
55 beemer lethal malformation syndrome 12.0
56 neural tube defects 11.9
57 chudley-mccullough syndrome 11.9
58 aase-smith syndrome i 11.8
59 myelomeningocele 11.8
60 chromosome 8q12.1-q21.2 deletion syndrome 11.7
61 papilloma of choroid plexus 11.7
62 hydranencephaly 11.5
63 mucopolysaccharidosis, type ii 11.5
64 schizencephaly 11.5
65 pettigrew syndrome 11.5
66 muscular dystrophy-dystroglycanopathy , type a, 1 11.5
67 chiari malformation 11.5
68 achondroplasia 11.5
69 congenital toxoplasmosis 11.5
70 melanosis, neurocutaneous 11.4
71 fanconi anemia, complementation group b 11.4
72 mucopolysaccharidosis, type vi 11.4
73 subependymal giant cell astrocytoma 11.4
74 vater/vacterl association 11.4
75 plasminogen deficiency, type i 11.4
76 otopalatodigital syndrome, type ii 11.4
77 syringomyelia, noncommunicating isolated 11.4
78 chiari malformation type ii 11.4
79 baker vinters syndrome 11.4
80 faye-petersen-ward-carey syndrome 11.4
81 kozlowski brown hardwick syndrome 11.4
82 palmer pagon syndrome 11.4
83 schwartz cohen-addad lambert syndrome 11.4
84 vacterl hydrocephaly 11.4
85 craniosynostosis 11.4
86 encephalocele 11.3
87 cellular ependymoma 11.3
88 meningocele 11.3
89 porencephaly 11.3
90 primary ciliary dyskinesia 11.3
91 hydromyelia 11.3
92 hemangioblastoma 11.3
93 fanconi anemia, complementation group a 11.3
94 corpus callosum, agenesis of 11.3
95 meningoencephalocele 11.3
96 syringohydromyelia 11.3
97 pineocytoma 11.3
98 bobble-head doll syndrome 11.3
99 colpocephaly 11.3
100 vein of galen aneurysm 11.3
101 hajdu-cheney syndrome 11.3
102 alexander disease 11.3
103 multiple sulfatase deficiency 11.3
104 ring chromosome 6 11.3
105 congenital plasminogen deficiency 11.3
106 hydrolethalus syndrome 1 11.3
107 isotretinoin embryopathy-like syndrome 11.3
108 mannosidosis, alpha b, lysosomal 11.3
109 marden-walker syndrome 11.3
110 mental retardation, buenos aires type 11.3
111 ciliary dyskinesia, primary, 43 11.3
112 9q22.3 microdeletion 11.3
113 crouzon syndrome with acanthosis nigricans 11.2
114 scheie syndrome 11.1
115 colloid cysts of third ventricle 11.1
116 lissencephaly 5 11.1
117 cole-carpenter syndrome 2 11.1
118 choroid plexus cancer 11.1
119 diencephalic syndrome 11.1
120 cennamo gangemi syndrome 11.1
121 spina bifida cystica 11.1
122 spina bifida aperta 11.0
123 myelocystocele 11.0
124 amyloidosis, hereditary, transthyretin-related 11.0
125 greig cephalopolysyndactyly syndrome 11.0
126 craniofacial dyssynostosis with short stature 11.0
127 craniotelencephalic dysplasia 11.0
128 dandy-walker malformation with postaxial polydactyly 11.0
129 mucopolysaccharidosis, type vii 11.0
130 muscular dystrophy-dystroglycanopathy , type a, 3 11.0
131 omphalocele-cleft palate syndrome, lethal 11.0
132 canavan disease 11.0
133 mend syndrome 11.0
134 chromosome 2q37 deletion syndrome 11.0
135 microhydranencephaly 11.0
136 encephalocraniocutaneous lipomatosis 11.0
137 brain malformations with or without urinary tract defects 11.0
138 craniofacial anomalies and anterior segment dysgenesis syndrome 11.0
139 brain abnormalities, neurodegeneration, and dysosteosclerosis 11.0
140 ciliary dyskinesia, primary, 42 11.0
141 coenurosis 11.0
142 early congenital syphilis 11.0
143 ankyloblepharon filiforme imperforate anus 11.0
144 congenital laryngeal palsy 11.0
145 fetal retinoid syndrome 11.0
146 macrocephaly-short stature-paraplegia syndrome 11.0
147 muscle eye brain disease 11.0
148 rosette-forming glioneuronal tumor 11.0
149 warfarin syndrome 11.0
150 nonsyndromic holoprosencephaly 11.0
151 nevus, epidermal 10.8 PTEN PIK3R2 FGFR3 FGFR2 AKT3
152 intracranial hypertension 10.7
153 meningitis 10.7
154 hemifacial hyperplasia 10.7 FGFR3 FGFR2
155 hypomelanosis of ito 10.7 PLOD1 ARFGEF2 AKT3
156 rare surgical neurologic disease 10.6
157 osteoglophonic dysplasia 10.6 FGFR3 FGFR2
158 blake pouch cyst 10.6
159 testicular spermatocytic seminoma 10.6 FGFR3 FGFR2
160 tuberculous meningitis 10.6
161 hypertelorism, microtia, facial clefting syndrome 10.6 FGFR3 FGFR2
162 ocular motor apraxia 10.5
163 cerebral atrophy 10.5
164 syringomyelia 10.5
165 luteoma 10.5 FGFR3 FGFR2
166 ataxia and polyneuropathy, adult-onset 10.5
167 dementia 10.5
168 head injury 10.5
169 aneurysm 10.4
170 headache 10.4
171 cysticercosis 10.4
172 arachnoid cysts, intracranial 10.4
173 papilledema 10.4
174 alzheimer disease 10.4
175 chromosome 17p13.3, centromeric, duplication syndrome 10.4 WDR81 DPH1
176 arteriovenous malformation 10.4
177 cerebral palsy 10.4
178 traumatic brain injury 10.4
179 encephalopathy 10.4
180 cerebrovascular disease 10.4
181 spinal arachnoiditis 10.4
182 arachnoiditis 10.4
183 neurilemmoma 10.3
184 paraplegia 10.3
185 toxoplasmosis 10.3
186 squamous cell papilloma 10.3
187 papilloma 10.3
188 vascular dementia 10.3
189 hydrops, lactic acidosis, and sideroblastic anemia 10.3
190 meningoencephalitis 10.3
191 acoustic neuroma 10.3
192 yemenite deaf-blind hypopigmentation syndrome 10.3
193 bacterial meningitis 10.3
194 mumps 10.3
195 apraxia 10.3
196 encephalitis 10.3
197 brain injury 10.3
198 cerebral aneurysms 10.3
199 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.3
200 glioma 10.3
201 spasticity 10.3
202 glial tumor 10.3
203 astrocytoma 10.3
204 holoprosencephaly 10.3
205 uterine carcinosarcoma 10.3 PTEN L1CAM FGFR2
206 brain edema 10.3
207 seizure disorder 10.3
208 benign ependymoma 10.2
209 pathologic nystagmus 10.2
210 sarcoidosis 1 10.2
211 intracranial hypertension, idiopathic 10.2
212 47,xyy 10.2
213 neurofibromatosis, type iv, of riccardi 10.2
214 mutism 10.2
215 macrocephaly/megalencephaly syndrome, autosomal recessive 10.2
216 tremor 10.2
217 strabismus 10.2
218 mammary paget's disease 10.2
219 mechanical strabismus 10.2
220 3-methylglutaconic aciduria, type iii 10.2
221 supranuclear palsy, progressive, 1 10.2
222 polydactyly 10.2
223 visual epilepsy 10.2
224 neurosarcoidosis 10.2
225 vascular disease 10.2
226 gait apraxia 10.2
227 precocious puberty 10.2
228 hypotonia 10.2
229 polymicrogyria with or without vascular-type ehlers-danlos syndrome 10.1
230 aphasia 10.1
231 intracranial aneurysm 10.1
232 amenorrhea 10.1
233 teratoma 10.1
234 akinetic mutism 10.1
235 medulloblastoma 10.1
236 meningioma, radiation-induced 10.1
237 meningioma, familial 10.1
238 thrombosis 10.1
239 spinal meningioma 10.1
240 epilepsy 10.1
241 secretory meningioma 10.1
242 lymphoplasmacyte-rich meningioma 10.1
243 diabetes insipidus 10.1
244 cryptococcal meningitis 10.1
245 hemiplegia 10.1
246 aseptic meningitis 10.1
247 tuberous sclerosis 10.1
248 lupus erythematosus 10.1
249 cleft lip 10.1
250 otitis media 10.1
251 craniopharyngioma 10.1
252 intracranial hypotension 10.1
253 binswanger's disease 10.1
254 overgrowth syndrome 10.1
255 systemic lupus erythematosus 10.1
256 anencephaly 10.1
257 aceruloplasminemia 10.1
258 chorea, childhood-onset, with psychomotor retardation 10.1
259 sleep apnea 10.1
260 sensorineural hearing loss 10.1
261 chronic meningitis 10.1
262 amnestic disorder 10.1
263 choreatic disease 10.1
264 neuroma 10.1
265 glioblastoma multiforme 10.1
266 adenoma 10.1
267 subcortical arteriosclerotic encephalopathy 10.1
268 frontotemporal dementia 10.1
269 pituitary adenoma 10.1
270 intracranial cysts 10.1
271 chiari malformation type i 10.0
272 hypertelorism 10.0
273 hypervitaminosis a 10.0
274 branchiootic syndrome 1 10.0
275 alacrima, achalasia, and mental retardation syndrome 10.0
276 low compliance bladder 10.0
277 lymphocytic choriomeningitis 10.0
278 guillain-barre syndrome 10.0
279 periventricular leukomalacia 10.0
280 status epilepticus 10.0
281 hemangioma 10.0
282 mature teratoma 10.0
283 juvenile pilocytic astrocytoma 10.0
284 vasculitis 10.0
285 learning disability 10.0
286 hypertensive encephalopathy 10.0
287 muscular dystrophy 10.0
288 pik3ca-related segmental overgrowth 10.0
289 cerebrospinal fluid leak 10.0
290 cleft lip/palate 10.0
291 huntington disease 10.0
292 parkinson disease, late-onset 10.0
293 trigeminal neuralgia 10.0
294 immune deficiency disease 10.0
295 mucopolysaccharidosis-plus syndrome 10.0
296 scoliosis 10.0
297 osteopetrosis 10.0
298 thrombocytopenia 10.0
299 arteriosclerosis 10.0
300 exophthalmos 10.0
301 hypopituitarism 10.0
302 spastic paraparesis 10.0
303 cleft palate, isolated 10.0
304 factor viii deficiency 10.0
305 hirschsprung disease 1 10.0
306 lipomatosis, multiple 10.0
307 polydactyly, postaxial, type a1 10.0
308 hemophilia a 10.0
309 corpus callosum, agenesis of, with facial anomalies and cerebellar ataxia 10.0
310 lissencephaly 10.0
311 benign teratoma 10.0
312 pleomorphic lipoma 10.0
313 cortical blindness 10.0
314 synostosis 10.0
315 gaucher's disease 10.0
316 cystic teratoma 10.0
317 48,xyyy 10.0
318 spinal cord injury 10.0
319 pituitary adenoma, prolactin-secreting 10.0
320 intraocular pressure quantitative trait locus 10.0
321 muscular dystrophy, congenital, lmna-related 10.0
322 neurogenic bladder 10.0
323 lateral sinus thrombosis 10.0
324 syphilis 10.0
325 movement disease 10.0
326 herpes simplex 10.0
327 rubella 10.0
328 hypereosinophilic syndrome 10.0
329 hemophilia 10.0
330 myotonic dystrophy 10.0
331 chromosomal triplication 10.0
332 dwarfism 10.0
333 occipital encephalocele 10.0
334 pfeiffer syndrome 9.9
335 migraine with or without aura 1 9.9
336 obsessive-compulsive disorder 9.9
337 down syndrome 9.9
338 gaucher disease, type i 9.9
339 kearns-sayre syndrome 9.9
340 brittle bone disorder 9.9
341 autosomal recessive disease 9.9
342 ptosis 9.9
343 brain compression 9.9
344 listeria meningitis 9.9
345 oligohydramnios 9.9
346 eclampsia 9.9
347 constipation 9.9
348 histiocytosis 9.9
349 cranial nerve palsy 9.9
350 infertility 9.9
351 conjunctivitis 9.9
352 peritonitis 9.9
353 nervous system disease 9.9
354 chorioretinitis 9.9
355 diabetes mellitus 9.9
356 choroid plexus cyst 9.9
357 ligneous conjunctivitis 9.9
358 neonatal meningitis 9.9
359 x-linked complicated spastic paraplegia type 1 9.9
360 myoclonus 9.9
361 rhombencephalosynapsis 9.9
362 alcohol dependence 9.9
363 arteriovenous malformations of the brain 9.9
364 crouzon syndrome 9.9
365 attention deficit-hyperactivity disorder 9.9
366 rheumatoid arthritis 9.9
367 thrombophilia due to thrombin defect 9.9
368 tracheoesophageal fistula with or without esophageal atresia 9.9
369 tuberous sclerosis 1 9.9
370 enterocolitis 9.9
371 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.9
372 hydrops fetalis, nonimmune 9.9
373 ciliary dyskinesia, primary, 1 9.9
374 abnormal hair, joint laxity, and developmental delay 9.9
375 corpus callosum, partial agenesis of, x-linked 9.9
376 patent ductus arteriosus 1 9.9
377 alkuraya-kucinskas syndrome 9.9
378 brachydactyly 9.9
379 siderosis 9.9
380 eosinophilic meningitis 9.9
381 pre-eclampsia 9.9
382 microphthalmia 9.9
383 respiratory failure 9.9
384 male infertility 9.9
385 locked-in syndrome 9.9
386 quadriplegia 9.9
387 polyneuropathy 9.9
388 facial paralysis 9.9
389 heart septal defect 9.9
390 germinoma 9.9
391 agnosia 9.9
392 situs inversus 9.9
393 cataract 9.9
394 arthritis 9.9
395 mucormycosis 9.9
396 polyhydramnios 9.9
397 perinatal necrotizing enterocolitis 9.9
398 pulmonary embolism 9.9
399 hydrocele 9.9
400 cerebellar hypoplasia 9.9
401 corticobasal degeneration 9.9
402 growth hormone deficiency 9.9
403 syncope 9.9
404 cerebellar malformation 9.9
405 superficial siderosis 9.9
406 ciliopathy 9.9
407 congenital amyoplasia 9.9
408 apert syndrome 9.8
409 cerebral amyloid angiopathy, cst3-related 9.8
410 autoimmune disease 9.8
411 gastroesophageal reflux 9.8
412 epidermoid cysts 9.8
413 neurofibromatosis, type i 9.8
414 noonan syndrome 1 9.8
415 schizophrenia 9.8
416 torticollis 9.8
417 varicose veins 9.8
418 joubert syndrome 1 9.8
419 cryptorchidism, unilateral or bilateral 9.8
420 langerhans cell histiocytosis 9.8
421 west syndrome 9.8
422 pulmonary hypertension 9.8
423 exanthem 9.8
424 cardiac arrest 9.8
425 inguinal hernia 9.8
426 mastoiditis 9.8
427 bone disease 9.8
428 asymptomatic neurosyphilis 9.8
429 monocular esotropia 9.8
430 suppression amblyopia 9.8
431 amblyopia 9.8
432 leukodystrophy 9.8
433 malignant hypertension 9.8
434 hydronephrosis 9.8
435 sarcoma 9.8
436 keratomalacia 9.8
437 alternating exotropia 9.8
438 exotropia 9.8
439 listeriosis 9.8
440 clubfoot 9.8
441 cryptococcosis 9.8
442 hypogonadism 9.8
443 spondylosis 9.8
444 hereditary spastic paraplegia 9.8
445 glomerulonephritis 9.8
446 purpura 9.8
447 brain stem infarction 9.8
448 hyperglycemia 9.8
449 brain stem glioma 9.8
450 myopathy 9.8
451 spindle cell sarcoma 9.8
452 pituitary gland disease 9.8
453 spinal stenosis 9.8
454 b-cell lymphoma 9.8
455 hypogonadotropism 9.8
456 measles 9.8
457 bronchiectasis 9.8
458 refractive error 9.8
459 esotropia 9.8
460 congenital zika syndrome 9.8
461 neurosyphilis 9.8
462 pseudo-turner syndrome 9.8
463 cerebral arteriosclerosis 9.8
464 dementia - subcortical 9.8
465 specific language disorder 9.8
466 pneumococcal meningitis 9.8
467 pik3ca-related overgrowth syndrome 9.8
468 central nervous system malformation 9.8
469 lobar holoprosencephaly 9.8
470 x-linked complex spastic paraplegia 9.8
471 atrial standstill 1 9.8
472 hypercarotenemia and vitamin a deficiency, autosomal dominant 9.8
473 creutzfeldt-jakob disease 9.8
474 multiple sclerosis 9.8
475 dementia, lewy body 9.8
476 hypercholesterolemia, familial, 1 9.8
477 multiple system atrophy 1 9.8
478 klippel-trenaunay-weber syndrome 9.8
479 hemifacial microsomia 9.8
480 retinal detachment 9.8
481 tetralogy of fallot 9.8
482 renal hypodysplasia/aplasia 1 9.8
483 adducted thumbs syndrome 9.8
484 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.8
485 baller-gerold syndrome 9.8
486 diastematomyelia 9.8
487 galactosemia 9.8
488 fragile x syndrome 9.8
489 thumbs, congenital clasped 9.8
490 fryns microphthalmia syndrome 9.8
491 stroke, ischemic 9.8
492 homocysteinemia 9.8
493 glycine encephalopathy 9.8
494 major affective disorder 8 9.8
495 major affective disorder 9 9.8
496 lung cancer susceptibility 3 9.8
497 aspergillosis 9.8
498 leukemia, acute lymphoblastic 3 9.8
499 global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies 9.8
500 helix syndrome 9.8
501 periventricular nodular heterotopia 9.8
502 chorioamnionitis 9.8
503 vitamin b12 deficiency 9.8
504 dextro-looped transposition of the great arteries 9.8
505 viral meningitis 9.8
506 endocarditis 9.8
507 klippel-feil syndrome 9.8
508 hypospadias 9.8
509 spastic diplegia 9.8
510 cerebral arteritis 9.8
511 cardiac tamponade 9.8
512 cauda equina syndrome 9.8
513 nephrotic syndrome 9.8
514 hemosiderosis 9.8
515 pancytopenia 9.8
516 nephrocalcinosis 9.8
517 acute cystitis 9.8
518 coccidioidomycosis 9.8
519 neuroleptic malignant syndrome 9.8
520 hypothyroidism 9.8
521 methylmalonic acidemia 9.8
522 candidiasis 9.8
523 alcohol use disorder 9.8
524 pneumothorax 9.8
525 atrial heart septal defect 9.8
526 optic nerve disease 9.8
527 giant cell tumor 9.8
528 hyperostosis 9.8
529 agammaglobulinemia 9.8
530 capillary hemangioma 9.8
531 antiphospholipid syndrome 9.8
532 myelitis 9.8
533 bipolar disorder 9.8
534 middle cerebral artery infarction 9.8
535 pleural empyema 9.8
536 cavernous hemangioma 9.8
537 paget's disease of bone 9.8
538 acquired immunodeficiency syndrome 9.8
539 muscular atrophy 9.8
540 neuroblastoma 9.8
541 end stage renal failure 9.8
542 influenza 9.8
543 subacute delirium 9.8
544 neuromyelitis optica 9.8
545 amyloidosis 9.8
546 homocystinuria 9.8
547 neurofibroma 9.8
548 alopecia 9.8
549 cytokine deficiency 9.8
550 mollaret meningitis 9.8
551 parainfluenza virus type 3 9.8
552 pure autonomic failure 9.8
553 weber syndrome 9.8
554 back pain 9.8
555 cerebral hypoxia 9.8
556 hypoxia 9.8
557 mucopolysaccharidoses 9.8
558 pituitary tumors 9.8
559 aniridia 1 9.7
560 anisocoria 9.7
561 apnea, obstructive sleep 9.7
562 basal cell nevus syndrome 9.7
563 clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly 9.7
564 coloboma of macula 9.7
565 major affective disorder 1 9.7
566 diabetes insipidus, nephrogenic, autosomal 9.7
567 hand skill, relative 9.7
568 diaphragmatic hernia, congenital 9.7
569 spondylosis, cervical 9.7
570 chromosome 2q35 duplication syndrome 9.7
571 thumb deformity 9.7
572 von hippel-lindau syndrome 9.7
573 carpenter syndrome 1 9.7
574 anus, imperforate 9.7
575 autism 9.7
576 cystic fibrosis 9.7
577 fanconi anemia, complementation group c 9.7
578 gaucher disease, type ii 9.7
579 gaucher disease, type iii 9.7
580 gaucher disease, type iiic 9.7
581 hemihyperplasia, isolated 9.7
582 holoprosencephaly 1 9.7
583 meckel syndrome, type 1 9.7
584 myopathy, congenital 9.7
585 peters-plus syndrome 9.7
586 pierre robin syndrome 9.7
587 pituitary hormone deficiency, combined, 2 9.7
588 epilepsy, pyridoxine-dependent 9.7
589 insulin-like growth factor i 9.7
590 adrenoleukodystrophy 9.7
591 tubulin, beta 9.7
592 calvarial hyperostosis 9.7
593 coffin-lowry syndrome 9.7
594 focal dermal hypoplasia 9.7
595 aging 9.7
596 band heterotopia 9.7
597 wilms tumor 5 9.7
598 ossification of the posterior longitudinal ligament of spine 9.7
599 aneurysmal bone cysts 9.7
600 gastrointestinal stromal tumor 9.7
601 cinca syndrome 9.7
602 anxiety 9.7
603 gaucher disease, perinatal lethal 9.7
604 granulomatosis with polyangiitis 9.7
605 rhabdoid tumor predisposition syndrome 1 9.7
606 human immunodeficiency virus type 1 9.7
607 lipomyelomeningocele 9.7
608 malaria 9.7
609 diabetes mellitus, ketosis-prone 9.7
610 lissencephaly 4 9.7
611 angina pectoris 9.7
612 deficiency anemia 9.7
613 distal arthrogryposis 9.7
614 dyskinetic cerebral palsy 9.7
615 diffuse large b-cell lymphoma 9.7
616 paraganglioma 9.7
617 fibroma 9.7
618 cerebellar medulloblastoma 9.7
619 brain meningioma 9.7
620 spinal disease 9.7
621 bone resorption disease 9.7
622 polycystic kidney disease 9.7
623 tabes dorsalis 9.7
624 venous insufficiency 9.7
625 esophageal atresia 9.7
626 rickets 9.7
627 abducens nerve disease 9.7
628 cholesteatoma of middle ear 9.7
629 brucellosis 9.7
630 enophthalmos 9.7
631 vitamin k deficiency bleeding 9.7
632 epidural abscess 9.7
633 fungal meningitis 9.7
634 allergic hypersensitivity disease 9.7
635 bronchopneumonia 9.7
636 transient global amnesia 9.7
637 uveitis 9.7
638 diarrhea 9.7
639 patent foramen ovale 9.7
640 spinal cord melanoma 9.7
641 central neurocytoma 9.7
642 echinococcosis 9.7
643 mental depression 9.7
644 central nervous system tuberculosis 9.7
645 ventricular septal defect 9.7
646 pineoblastoma 9.7
647 histoplasmosis 9.7
648 neuritis 9.7
649 impotence 9.7
650 encephalomalacia 9.7
651 atypical teratoid rhabdoid tumor 9.7
652 keratopathy 9.7
653 thrombophilia 9.7
654 relapsing polychondritis 9.7
655 glycogen storage disease 9.7
656 pulmonary tuberculosis 9.7
657 malignant glioma 9.7
658 grade iii astrocytoma 9.7
659 oligodendroglioma 9.7
660 cerebellopontine angle tumor 9.7
661 neurilemmoma of the fifth cranial nerve 9.7
662 central nervous system lymphoma 9.7
663 central nervous system disease 9.7
664 inappropriate adh syndrome 9.7
665 sagittal sinus thrombosis 9.7
666 rhabdoid cancer 9.7
667 protein c deficiency 9.7
668 heart valve disease 9.7
669 tricuspid valve insufficiency 9.7
670 hypertrichosis 9.7
671 rhinitis 9.7
672 dysgraphia 9.7
673 cauda equina neoplasm 9.7
674 cerebellar astrocytoma 9.7
675 myxopapillary ependymoma 9.7
676 ganglioglioma 9.7
677 dystonia 9.7
678 spinal cord ependymoma 9.7
679 kidney disease 9.7
680 malignant peripheral nerve sheath tumor 9.7
681 congestive heart failure 9.7
682 double outlet right ventricle 9.7
683 connective tissue disease 9.7
684 inherited metabolic disorder 9.7
685 delusional disorder 9.7
686 tertiary syphilis 9.7
687 ileus 9.7
688 herpes zoster 9.7
689 chickenpox 9.7
690 neuropathy 9.7
691 speech disorder 9.7
692 scotoma 9.7
693 dextrocardia 9.7
694 hypoplastic left heart syndrome 9.7
695 hypoglycemia 9.7
696 albinism 9.7
697 craniofacial microsomia 9.7
698 isolated methylmalonic acidemia 9.7
699 absence of septum pellucidum 9.7
700 acalvaria 9.7
701 adrenomyeloneuropathy 9.7
702 anaplastic oligodendroglioma 9.7
703 cerebellar agenesis 9.7
704 congenital cytomegalovirus 9.7
705 congenital rubella 9.7
706 dextrocardia with situs inversus 9.7
707 diffuse intrinsic pontine glioma 9.7
708 exencephaly 9.7
709 germ cells tumors 9.7
710 gigantism 9.7
711 herpes zoster ophthalmicus 9.7
712 horseshoe kidney 9.7
713 idiopathic hypertrophic pachymeningitis 9.7
714 phacomatosis pigmentovascularis 9.7
715 primary central nervous system lymphoma 9.7
716 subependymoma 9.7
717 syringobulbia 9.7
718 angiomatosis 9.7
719 anoxia 9.7
720 cavernous malformation 9.7
721 cytomegalovirus infection 9.7
722 dysphagia 9.7
723 persistent vegetative state 9.7
724 angioosteohypertrophic syndrome 9.7
725 isolated craniosynostosis 9.7
726 rapidly involuting congenital hemangioma 9.7
727 inflammatory myopathy with abundant macrophages 9.7
728 neurenteric cyst 9.7
729 ring chromosome 9.7
730 igg4-related pachymeningitis 9.7
731 neonatal lupus erythematosus 9.7
732 spontaneous intracranial hypotension 9.7
733 cerebral visual impairment 9.7
734 renal dysplasia 9.7
735 rare tumor 9.7
736 alobar holoprosencephaly 9.7
737 abducens palsy 9.5
738 adult syndrome 9.5
739 amyotrophic lateral sclerosis 1 9.5
740 spondyloarthropathy 1 9.5
741 aplasia cutis congenita, nonsyndromic 9.5
742 atherosclerosis susceptibility 9.5
743 bladder cancer 9.5
744 branchiootorenal syndrome 1 9.5
745 campomelic dysplasia 9.5
746 breast cancer 9.5
747 candidiasis, familial, 1 9.5
748 carpal tunnel syndrome 9.5
749 cat eye syndrome 9.5
750 cerebral cavernous malformations 9.5
751 sotos syndrome 1 9.5
752 cleidocranial dysplasia 9.5
753 seizures, benign familial neonatal, 1 9.5
754 craniometaphyseal dysplasia, autosomal dominant 9.5
755 cri-du-chat syndrome 9.5
756 cryoglobulinemia, familial mixed 9.5
757 deafness, unilateral 9.5
758 duane retraction syndrome 1 9.5
759 dystonia 1, torsion, autosomal dominant 9.5
760 multiple endocrine neoplasia, type i 9.5
761 exudative vitreoretinopathy 1 9.5
762 coffin-siris syndrome 1 9.5
763 hair whorl 9.5
764 hemifacial spasm, familial 9.5
765 renal cell carcinoma, nonpapillary 9.5
766 endosteal hyperostosis, autosomal dominant 9.5
767 kabuki syndrome 1 9.5
768 kleeblattschaedel 9.5
769 larsen syndrome 9.5
770 lentigines 9.5
771 lenz-majewski hyperostotic dwarfism 9.5
772 hypomagnesemia 2, renal 9.5
773 meckel diverticulum 9.5
774 megalencephaly, autosomal dominant 9.5
775 macrodactyly 9.5
776 metaphyseal chondrodysplasia, schmid type 9.5
777 microcephaly, autosomal dominant 9.5
778 holoprosencephaly 2 9.5
779 nevus anemicus 9.5
780 ocular dominance 9.5
781 optic nerve hypoplasia, bilateral 9.5
782 osteogenesis imperfecta, type ii 9.5
783 osteoporosis 9.5
784 nephrolithiasis, calcium oxalate 9.5
785 pheochromocytoma 9.5
786 pick disease of brain 9.5
787 polykaryocytosis inducer 9.5
788 radioulnar synostosis 9.5
789 raynaud disease 9.5
790 dowling-degos disease 1 9.5
791 scleroderma, familial progressive 9.5
792 shprintzen-goldberg craniosynostosis syndrome 9.5
793 septooptic dysplasia 9.5
794 spinal intradural arachnoid cysts 9.5
795 odontochondrodysplasia 9.5
796 sturge-weber syndrome 9.5
797 teeth present at birth 9.5
798 telecanthus 9.5
799 thanatophoric dysplasia, type i 9.5
800 thanatophoric dysplasia, type ii 9.5
801 thrombocytopenic purpura, autoimmune 9.5
802 thrombophilia due to activated protein c resistance 9.5
803 triiodothyronine receptor auxiliary protein 9.5
804 vesicoureteral reflux 1 9.5
805 wilms tumor, aniridia, genitourinary anomalies, and mental retardation syndrome 9.5
806 acrocallosal syndrome 9.5
807 short-rib thoracic dysplasia 1 with or without polydactyly 9.5
808 cockayne syndrome a 9.5
809 craniodiaphyseal dysplasia 9.5
810 craniosynostosis with fibular aplasia 9.5
811 cystinosis, nephropathic 9.5
812 mitochondrial complex iv deficiency 9.5
813 leukoencephalopathy, hereditary diffuse, with spheroids 9.5
814 duodenal atresia 9.5
815 proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome 9.5
816 endocardial fibroelastosis 9.5
817 fanconi anemia, complementation group d2 9.5
818 gastroschisis 9.5
819 glycogen storage disease ii 9.5
820 hemangiopericytoma, malignant 9.5
821 homocystinuria due to deficiency of n -methylenetetrahydrofolate reductase activity 9.5
822 urofacial syndrome 1 9.5
823 krabbe disease 9.5
824 epilepsy, focal, with speech disorder and with or without mental retardation 9.5
825 multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects 9.5
826 donohue syndrome 9.5
827 megalocornea 9.5
828 metachromatic leukodystrophy 9.5
829 moyamoya disease 1 9.5
830 mucolipidosis ii alpha/beta 9.5
831 myasthenia gravis 9.5
832 opsismodysplasia 9.5
833 phenylketonuria 9.5
834 short-rib thoracic dysplasia 6 with or without polydactyly 9.5
835 pycnodysostosis 9.5
836 respiratory distress syndrome in premature infants 9.5
837 knobloch syndrome 1 9.5
838 rothmund-thomson syndrome, type 2 9.5
839 smith-lemli-opitz syndrome 9.5
840 sudden infant death syndrome 9.5
841 gm2-gangliosidosis, ab variant 9.5
842 tay-sachs disease 9.5
843 thymoma, familial 9.5
844 graves disease 1 9.5
845 spondylocostal dysostosis 1, autosomal recessive 9.5
846 xeroderma pigmentosum, variant type 9.5
847 opitz gbbb syndrome, type i 9.5
848 body mass index quantitative trait locus 11 9.5
849 orofaciodigital syndrome viii 9.5
850 autism x-linked 2 9.5
851 wiskott-aldrich syndrome 9.5
852 arts syndrome 9.5
853 aicardi syndrome 9.5
854 opitz-kaveggia syndrome 9.5
855 incontinentia pigmenti 9.5
856 lowe oculocerebrorenal syndrome 9.5
857 muscular dystrophy, duchenne type 9.5
858 epilepsy, childhood absence 1 9.5
859 gomez-lopez-hernandez syndrome 9.5
860 autoimmune lymphoproliferative syndrome 9.5
861 body mass index quantitative trait locus 9 9.5
862 muenke syndrome 9.5
863 acromesomelic dysplasia, maroteaux type 9.5
864 astigmatism 9.5
865 body mass index quantitative trait locus 8 9.5
866 intervertebral disc disease 9.5
867 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.5
868 optic atrophy 4 9.5
869 tetralogy of fallot syndrome, autosomal recessive 9.5
870 pars planitis 9.5
871 body mass index quantitative trait locus 1 9.5
872 van der woude syndrome 2 9.5
873 anorexia nervosa 9.5
874 polymicrogyria, bilateral frontoparietal 9.5
875 hurler syndrome 9.5
876 nasopharyngeal carcinoma 9.5
877 meckel syndrome, type 3 9.5
878 lissencephaly 1 9.5
879 body mass index quantitative trait locus 4 9.5
880 body mass index quantitative trait locus 10 9.5
881 mycobacterium tuberculosis 1 9.5
882 body mass index quantitative trait locus 7 9.5
883 major depressive disorder 9.5
884 ciliary dyskinesia, primary, 3 9.5
885 choanal atresia, posterior 9.5
886 aplastic anemia 9.5
887 alzheimer disease 10 9.5
888 cortical dysplasia, complex, with other brain malformations 7 9.5
889 bone mineral density quantitative trait locus 8 9.5
890 body mass index quantitative trait locus 12 9.5
891 sarcoidosis 3 9.5
892 body mass index quantitative trait locus 14 9.5
893 bone mineral density quantitative trait locus 15 9.5
894 odontoid hypoplasia 9.5
895 cardiomyopathy, familial hypertrophic, 20 9.5
896 microcephaly-capillary malformation syndrome 9.5
897 tumor predisposition syndrome 9.5
898 hemorrhage, intracerebral 9.5
899 leukoencephalopathy, brain calcifications, and cysts 9.5
900 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.5
901 body mass index quantitative trait locus 18 9.5
902 hyperprolactinemia 9.5
903 alzheimer disease 18 9.5
904 optic atrophy 9 9.5
905 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.5
906 body mass index quantitative trait locus 19 9.5
907 body mass index quantitative trait locus 20 9.5
908 peripheral vascular disease 9.5
909 adrenal cortical carcinoma 9.5
910 streptococcus pneumonia 9.5
911 chikungunya 9.5
912 aspiration pneumonia 9.5
913 variola major 9.5
914 ross river fever 9.5
915 orofacial cleft 9.5
916 muscular dystrophy-dystroglycanopathy 9.5
917 asphyxiating thoracic dystrophy 9.5
918 oculocutaneous albinism 9.5
919 fetal alcohol syndrome 9.5
920 alcohol-related birth defect 9.5
921 anaplastic large cell lymphoma 9.5
922 atrioventricular block 9.5
923 hemidystonia 9.5
924 adrenal gland pheochromocytoma 9.5
925 spastic ataxia 9.5
926 sexual disorder 9.5
927 lymphoma 9.5
928 brain glioma 9.5
929 anosognosia 9.5
930 auditory agnosia 9.5
931 pain agnosia 9.5
932 organic acidemia 9.5
933 colitis 9.5
934 cogan syndrome 9.5
935 agraphia 9.5
936 basal ganglia calcification 9.5
937 stuttering 9.5
938 parietal foramina 9.5
939 penicillin allergy 9.5
940 purpura fulminans 9.5
941 anterior segment dysgenesis 9.5
942 griscelli syndrome 9.5
943 x-linked recessive disease 9.5
944 acromesomelic dysplasia 9.5
945 spina bifida occulta 9.5
946 myoglobinuria 9.5
947 meningococcal meningitis 9.5
948 haemophilus meningitis 9.5
949 renal hypoplasia 9.5
950 mucolipidosis 9.5
951 hypogonadotropic hypogonadism 9.5
952 col4a1-related familial vascular leukoencephalopathy 9.5
953 sparganosis 9.5
954 intracranial abscess 9.5
955 cholelithiasis 9.5
956 parotitis 9.5
957 blepharophimosis 9.5
958 bacterial infectious disease 9.5
959 common cold 9.5
960 cystinosis 9.5
961 japanese encephalitis 9.5
962 strongyloidiasis 9.5
963 lipoid nephrosis 9.5
964 spastic hemiplegia 9.5
965 asphyxia neonatorum 9.5
966 pseudomembranous conjunctivitis 9.5
967 hypoparathyroidism 9.5
968 primary hyperparathyroidism 9.5
969 rabies 9.5
970 pituitary apoplexy 9.5
971 retinal microaneurysm 9.5
972 vertebral artery occlusion 9.5
973 tetanus 9.5
974 subdural empyema 9.5
975 pulmonary edema 9.5
976 heart disease 9.5
977 choroiditis 9.5
978 hemopericardium 9.5
979 suppurative otitis media 9.5
980 oculomotor nerve paralysis 9.5
981 streptococcal meningitis 9.5
982 lyme disease 9.5
983 iron deficiency anemia 9.5
984 leukocoria 9.5
985 pericardial effusion 9.5
986 myopia 9.5
987 sarcoid meningitis 9.5
988 optic neuritis 9.5
989 inflammatory spondylopathy 9.5
990 pica disease 9.5
991 alveolar echinococcosis 9.5
992 neutropenia 9.5
993 anisometropia 9.5
994 cough variant asthma 9.5
995 marasmus 9.5
996 hematocele of tunica vaginalis testis 9.5
997 entropion 9.5
998 sulfhemoglobinemia 9.5
999 bell's palsy 9.5
1000 von willebrand's disease 9.5
1001 hepatic coma 9.5
1002 dyscalculia 9.5
1003 newborn respiratory distress syndrome 9.5
1004 mucopolysaccharidosis iii 9.5
1005 lagophthalmos 9.5
1006 hereditary spherocytosis 9.5
1007 plasmodium vivax malaria 9.5
1008 severe pre-eclampsia 9.5
1009 hellp syndrome 9.5
1010 gout 9.5
1011 pure red-cell aplasia 9.5
1012 skin sarcoidosis 9.5
1013 pulmonary sarcoidosis 9.5
1014 basilar artery occlusion 9.5
1015 hyperparathyroidism 9.5
1016 obstructive jaundice 9.5
1017 achromatopsia 9.5
1018 benign paroxysmal positional nystagmus 9.5
1019 toxic shock syndrome 9.5
1020 spinal cord sarcoma 9.5
1021 renal tubular acidosis 9.5
1022 leopard syndrome 9.5
1023 generalized anxiety disorder 9.5
1024 gonadal dysgenesis 9.5
1025 neuronal ceroid lipofuscinosis 9.5
1026 niemann-pick disease 9.5
1027 foster-kennedy syndrome 9.5
1028 axenfeld-rieger syndrome 9.5
1029 ectropion 9.5
1030 hypoglycemic coma 9.5
1031 mitral valve stenosis 9.5
1032 pericarditis 9.5
1033 ossifying fibroma 9.5
1034 hepatitis c 9.5
1035 viral hepatitis 9.5
1036 melanoma 9.5
1037 endodermal sinus tumor 9.5
1038 dysostosis 9.5
1039 bardet-biedl syndrome 9.5
1040 leiomyosarcoma 9.5
1041 hyperinsulinism 9.5
1042 exostosis 9.5
1043 ectodermal dysplasia 9.5
1044 focal epilepsy 9.5
1045 leptospirosis 9.5
1046 lateral sclerosis 9.5
1047 gastroenteritis 9.5
1048 iron metabolism disease 9.5
1049 gangliocytoma 9.5
1050 glomus tumor 9.5
1051 acromegaly 9.5
1052 retinal vascular disease 9.5
1053 kluver-bucy syndrome 9.5
1054 landau-kleffner syndrome 9.5
1055 familial nephrotic syndrome 9.5
1056 benign mesothelioma 9.5
1057 transitional cell carcinoma 9.5
1058 dysembryoplastic neuroepithelial tumor 9.5
1059 cryoglobulinemia 9.5
1060 newcastle disease 9.5
1061 cockayne syndrome 9.5
1062 cystic kidney disease 9.5
1063 adenocarcinoma 9.5
1064 germ cell cancer 9.5
1065 cystic lymphangioma 9.5
1066 lipid metabolism disorder 9.5
1067 lipomatosis 9.5
1068 progressive muscular atrophy 9.5
1069 spinal cord glioma 9.5
1070 spinal cord disease 9.5
1071 c-p angle neurinoma 9.5
1072 neurilemmomatosis 9.5
1073 demyelinating disease 9.5
1074 lipid pneumonia 9.5
1075 thymoma 9.5
1076 vaccinia 9.5
1077 gm2 gangliosidosis 9.5
1078 mood disorder 9.5
1079 mesenchymal cell neoplasm 9.5
1080 turner syndrome 9.5
1081 spinal cord intramedullary teratoma 9.5
1082 empty sella syndrome 9.5
1083 hermaphroditism 9.5
1084 intraventricular meningioma 9.5
1085 thrombophlebitis 9.5
1086 intestinal pseudo-obstruction 9.5
1087 gastritis 9.5
1088 tricuspid valve stenosis 9.5
1089 intracranial thrombosis 9.5
1090 dyslexia 9.5
1091 skull base meningioma 9.5
1092 bartter disease 9.5
1093 avian influenza 9.5
1094 hypokalemia 9.5
1095 bile duct cancer 9.5
1096 endophthalmitis 9.5
1097 mongolian spot 9.5
1098 diffuse glomerulonephritis 9.5
1099 ependymoblastoma 9.5
1100 spinal cord astrocytoma 9.5
1101 prosopagnosia 9.5
1102 essential tremor 9.5
1103 pineal gland cancer 9.5
1104 middle ear disease 9.5
1105 ovarian cyst 9.5
1106 borna disease 9.5
1107 urinary tract obstruction 9.5
1108 chronic inflammatory demyelinating polyradiculoneuropathy 9.5
1109 demyelinating polyneuropathy 9.5
1110 blepharospasm 9.5
1111 anterograde amnesia 9.5
1112 testicular yolk sac tumor 9.5
1113 internuclear ophthalmoplegia 9.5
1114 clear cell ependymoma 9.5
1115 pneumonia 9.5
1116 third cranial nerve disease 9.5
1117 peripheral nervous system disease 9.5
1118 subvalvular aortic stenosis 9.5
1119 hemolytic anemia 9.5
1120 meningeal melanocytoma 9.5
1121 gliomatosis cerebri 9.5
1122 cerebellopontine angle meningioma 9.5
1123 diffuse meningeal melanocytosis 9.5
1124 pulmonary valve stenosis 9.5
1125 progressive multifocal leukoencephalopathy 9.5
1126 viral encephalitis 9.5
1127 spondylitis 9.5
1128 juvenile rheumatoid arthritis 9.5
1129 spinal cord primitive neuroectodermal neoplasm 9.5
1130 skin tag 9.5
1131 t-cell leukemia 9.5
1132 thyroiditis 9.5
1133 meningothelial meningioma 9.5
1134 pineal region germinoma 9.5
1135 peptic ulcer disease 9.5
1136 carotid artery occlusion 9.5
1137 myocarditis 9.5
1138 appendicitis 9.5
1139 intestinal obstruction 9.5
1140 malignant hyperthermia 9.5
1141 ulcerative colitis 9.5
1142 myeloid leukemia 9.5
1143 smallpox 9.5
1144 mitochondrial encephalomyopathy 9.5
1145 autosomal dominant polycystic kidney disease 9.5
1146 narcolepsy 9.5
1147 hard palate cancer 9.5
1148 cholangitis 9.5
1149 otitis externa 9.5
1150 stomatitis 9.5
1151 toxocariasis 9.5
1152 hypertropia 9.5
1153 hypotropia 9.5
1154 miliary tuberculosis 9.5
1155 dacryocystocele 9.5
1156 drug dependence 9.5
1157 heterotaxy 9.5
1158 col1a1/2 osteogenesis imperfecta 9.5
1159 cleidocranial dysplasia spectrum disorder 9.5
1160 frem1 autosomal recessive disorders 9.5
1161 irf6-related disorders 9.5
1162 spondylocostal dysostosis, autosomal recessive 9.5
1163 x-linked otopalatodigital spectrum disorders 9.5
1164 aids dementia complex 9.5
1165 anaplastic ependymoma 9.5
1166 aortic arch interruption 9.5
1167 atlanto-axial fusion 9.5
1168 branchial arch defects 9.5
1169 broken heart syndrome 9.5
1170 bronchopulmonary dysplasia 9.5
1171 charles bonnet syndrome 9.5
1172 chromosome 15q deletion 9.5
1173 chromosome 1q deletion 9.5
1174 chromosome 6q deletion 9.5
1175 chromosome 8q duplication 9.5
1176 congenital muscular dystrophy due to dystroglycanopathy 9.5
1177 congenital varicella syndrome 9.5
1178 dipsogenic diabetes insipidus 9.5
1179 distal renal tubular acidosis 9.5
1180 fetal and neonatal alloimmune thrombocytopenia 9.5
1181 foix chavany marie syndrome 9.5
1182 gangliosidosis 9.5
1183 growth retardation hydrocephaly lung hypoplasia 9.5
1184 haemophilus influenzae 9.5
1185 hemimegalencephaly 9.5
1186 hemorrhagic shock and encephalopathy syndrome 9.5
1187 herpes simplex encephalitis 9.5
1188 hip subluxation 9.5
1189 human t-cell leukemia virus type 1 9.5
1190 hypothalamic obesity 9.5
1191 knobloch syndrome 9.5
1192 lymphosarcoma 9.5
1193 macrophage activation syndrome 9.5
1194 mosaic trisomy 22 9.5
1195 mosaic trisomy 9 9.5
1196 myoclonus epilepsy 9.5
1197 neonatal herpes 9.5
1198 neonatal stroke 9.5
1199 ogilvie syndrome 9.5
1200 oligoastrocytoma 9.5
1201 oto-palatal-digital syndrome 9.5
1202 pachygyria 9.5
1203 periodontal ehlers-danlos syndrome 9.5
1204 phocomelia 9.5
1205 pontine hemorrhage 9.5
1206 retinochoroidal coloboma 9.5
1207 rosai-dorfman disease 9.5
1208 sacrococcygeal teratoma 9.5
1209 single ventricular heart 9.5
1210 sirenomelia 9.5
1211 skeletal dysplasias 9.5
1212 spinal shock 9.5
1213 splenomegaly 9.5
1214 superficial siderosis of the central nervous system 9.5
1215 tarlov cysts 9.5
1216 thunderclap headache 9.5
1217 tracheobronchomalacia 9.5
1218 transverse myelitis 9.5
1219 trisomy 22 9.5
1220 raynaud phenomenon 9.5
1221 abdominal wall defect 9.5
1222 central precocious puberty 9.5
1223 depression 9.5
1224 farsightedness 9.5
1225 isolated pierre robin sequence 9.5
1226 multiple endocrine neoplasia 9.5
1227 autonomic dysfunction 9.5
1228 central cord syndrome 9.5
1229 hemifacial spasm 9.5
1230 hypersomnia 9.5
1231 hypertonia 9.5
1232 immune-mediated encephalomyelitis 9.5
1233 meningitis and encephalitis 9.5
1234 myopathy - thyrotoxic 9.5
1235 myotonia 9.5
1236 shaken baby syndrome 9.5
1237 spinal cord infarction 9.5
1238 whiplash 9.5
1239 posttransplant acute limbic encephalitis 9.5
1240 frontal encephalocele 9.5
1241 perioral myoclonia with absences 9.5
1242 cerebrofacial arteriovenous metameric syndrome 9.5
1243 supernumerary nostril 9.5
1244 kenny-caffey syndrome 9.5
1245 low-grade astrocytoma 9.5
1246 obsolete: atypical teratoid/rhabdoid tumor 9.5
1247 benign peripheral nerve sheath tumor 9.5
1248 diffuse leptomeningeal melanocytosis 9.5
1249 trisomy 1q 9.5
1250 bilateral polymicrogyria 9.5
1251 midline cerebral malformation 9.5
1252 hemihyperplasia-multiple lipomatosis syndrome 9.5
1253 fowler urethral sphincter dysfunction syndrome 9.5
1254 semilobar holoprosencephaly 9.5
1255 rare hereditary hemochromatosis 9.5
1256 congenital achiasma 9.5
1257 qualitative or quantitative defects of alpha-dystroglycan 9.5
1258 pseudo-meigs syndrome 9.5
1259 congenital hemangioma 9.5
1260 persistent idiopathic facial pain 9.5
1261 isolated oxycephaly 9.5
1262 argyria 9.5
1263 monosomy 9q22.3 9.5
1264 6q terminal deletion syndrome 9.5
1265 postinfectious vasculitis 9.5
1266 cobblestone lissencephaly 9.5
1267 congenital ectropion uveae 9.5
1268 functioning gonadotropic adenoma 9.5
1269 regional odontodysplasia 9.5
1270 autosomal trisomy 9.5
1271 cranial malformation 9.5
1272 congenital ectropion 9.5
1273 congenital arteriovenous fistula 9.5
1274 red cell aplasia 9.5
1275 posterior fossa malformation 9.5
1276 multiple congenital anomalies/dysmorphic syndrome-intellectual disability 9.5
1277 idiopathic syringomyelia 9.5

Graphical network of the top 20 diseases related to Hydrocephalus:



Diseases related to Hydrocephalus

Symptoms & Phenotypes for Hydrocephalus

UMLS symptoms related to Hydrocephalus:


seizures, tremor, back pain, pain, headache, syncope, chronic pain, sciatica, vertigo/dizziness, sleeplessness

GenomeRNAi Phenotypes related to Hydrocephalus according to GeneCards Suite gene sharing:

26 (showing 3, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.17 STK36
2 Decreased substrate adherent cell growth GR00193-A-2 9.17 AKT3 FGFR2
3 Decreased substrate adherent cell growth GR00193-A-3 9.17 AKT3 FGFR2 FGFR3 STK36

MGI Mouse Phenotypes related to Hydrocephalus:

45 (showing 12, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.36 AKT3 CCND2 FGFR2 FGFR3 HYDIN KIAA1109
2 growth/size/body region MP:0005378 10.36 AKT3 ARFGEF2 DPH1 FANCB FGFR2 FGFR3
3 cellular MP:0005384 10.32 AKT3 ARFGEF2 DPH1 FANCB FGFR2 FGFR3
4 mortality/aging MP:0010768 10.31 AKT3 ARFGEF2 CCND2 DPH1 FGFR2 FGFR3
5 cardiovascular system MP:0005385 10.24 AKT3 CCND2 FGFR2 FOXC1 HYDIN KIAA1109
6 nervous system MP:0003631 10.21 AKT3 ARFGEF2 CCND2 DPH1 FGFR2 FGFR3
7 craniofacial MP:0005382 10.11 DPH1 FGFR2 FGFR3 FOXC1 HYDIN L1CAM
8 reproductive system MP:0005389 10.03 AKT3 CCND2 FANCB FGFR2 FGFR3 FOXC1
9 respiratory system MP:0005388 9.76 DPH1 FGFR2 FGFR3 FOXC1 HYDIN PTEN
10 pigmentation MP:0001186 9.72 DPH1 FGFR2 FOXC1 L1CAM PTEN
11 skeleton MP:0005390 9.65 DPH1 FGFR2 FGFR3 FOXC1 HYDIN L1CAM
12 vision/eye MP:0005391 9.36 CCND2 DPH1 FGFR2 FGFR3 FOXC1 KIAA1109

Drugs & Therapeutics for Hydrocephalus

Drugs for Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 179, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Citalopram Approved Phase 4 59729-33-8 2771
2
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
3
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
4
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
5
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
6 Pharmaceutical Solutions Phase 4
7 Serotonin Uptake Inhibitors Phase 4
8 Muscarinic Antagonists Phase 4
9 Serotonin Agents Phase 4
10 Cholinergic Agents Phase 4
11 Cholinergic Antagonists Phase 4
12 Serotonin Receptor Agonists Phase 4
13 Anesthetics, Dissociative Phase 4
14 Excitatory Amino Acids Phase 4
15 Excitatory Amino Acid Antagonists Phase 4
16 Anesthetics Phase 4
17 Neurotransmitter Agents Phase 4
18 Adrenergic Agonists Phase 4
19 Hypnotics and Sedatives Phase 4
20 Adrenergic alpha-2 Receptor Agonists Phase 4
21 Analgesics, Non-Narcotic Phase 4
22 Anesthetics, General Phase 4
23 Central Nervous System Depressants Phase 4
24 Adrenergic Agents Phase 4
25 Analgesics Phase 4
26 Anesthetics, Intravenous Phase 4
27
Glycopyrrolate Phase 4 596-51-0 3494
28
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
29
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
30
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
31
Rifampicin Approved Phase 3 13292-46-1 5458213 5381226
32
Sodium citrate Approved, Investigational Phase 3 68-04-2
33
Caffeine Approved Phase 3 58-08-2 2519
34
Indomethacin Approved, Investigational Phase 3 53-86-1 3715
35
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
36
Acetaminophen Approved Phase 2, Phase 3 103-90-2 1983
37
Aspirin Approved, Vet_approved Phase 2, Phase 3 50-78-2 2244
38
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
39
Guaifenesin Approved, Investigational, Vet_approved Phase 2, Phase 3 93-14-1 3516
40
Naproxen Approved, Vet_approved Phase 2, Phase 3 22204-53-1 1302 156391
41
Codeine Approved, Illicit Phase 2, Phase 3 76-57-3 5284371
42
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
43
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743