Aliases & Classifications for Hydronephrosis

Summaries for Hydronephrosis

MalaCards based summary : Hydronephrosis is related to pyelonephritis and ureteral obstruction. An important gene associated with Hydronephrosis is C12orf57 (Chromosome 12 Open Reading Frame 57), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Etomidate and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include kidney, spinal cord and testis, and related phenotypes are immune system and integument

Wikipedia : 76 Hydronephrosis describes urine-filled dilation of the renal pelvis and/or calyces as a result of... more...

Related Diseases for Hydronephrosis

Diseases related to Hydronephrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 pyelonephritis 30.4 ALB CCL2 NAGLU
2 ureteral obstruction 30.3 AQP2 SLC12A1 TGFB1
3 peritonitis 29.9 ALB B2M CCL2
4 chronic kidney failure 29.2 ALB B2M TGFB1
5 autosomal dominant polycystic kidney disease 29.1 ALB AQP2 CCL2 EGF
6 kidney disease 28.3 ALB AQP2 B2M CCL2 NAGLU TGFB1
7 urinary tract obstruction 28.0 ALB AQP2 B2M CCL2 EGF NAGLU
8 hydronephrosis, congenital, with cleft palate, characteristic facies, hypotonia, and mental retardation 12.2
9 congenital anomalies of kidney and urinary tract 2 12.0
10 coloboma porencephaly hydronephrosis 11.9
11 urofacial syndrome 1 11.8
12 schinzel giedion syndrome 11.1
13 visceral myopathy 11.0
14 ehlers-danlos syndrome, musculocontractural type, 1 11.0
15 carpenter syndrome 1 10.9
16 perlman syndrome 10.9
17 vacterl association, x-linked, with or without hydrocephalus 10.9
18 urethral obstruction sequence 10.9
19 ritscher-schinzel syndrome 1 10.8
20 raine syndrome 10.8
21 otopalatodigital syndrome, type ii 10.8
22 mesomelia-synostoses syndrome 10.8
23 genitopatellar syndrome 10.8
24 arterial calcification of infancy 10.8
25 kleefstra syndrome 10.8
26 al-gazali-donnai-mueller syndrome 10.8
27 desmoid tumor 10.8
28 ring chromosome 10 10.8
29 split hand urinary anomalies spina bifida 10.8
30 immunodeficiency 43 10.6 ALB B2M
31 orthostatic proteinuria 10.5 ALB B2M
32 kidney hypertrophy 10.5 ALB TGFB1
33 diffuse glomerulonephritis 10.4 ALB B2M
34 acute kidney failure 10.4 ALB B2M EGF
35 intravascular large b-cell lymphoma 10.4 B2M MME
36 hepatorenal syndrome 10.3 ALB AQP2 NAGLU
37 microvascular complications of diabetes 3 10.3 ALB NAGLU TGFB1
38 adrenal cortical adenocarcinoma 10.2 EGF MME
39 lipoid nephrosis 10.2 ALB CCL2 NAGLU
40 ureteral disease 10.2 AQP2 CCL2 TGFB1
41 diabetic foot ulcers 10.2 TGFB1 TIMP1
42 vesicoureteral reflux 1 10.1
43 respiratory system disease 10.1 ALB CCL2 TGFB1
44 horseshoe kidney 10.0
45 bladder cancer 10.0
46 glomerulonephritis 10.0 ALB CCL2 TGFB1
47 impaired renal function disease 10.0 AQP2 SLC12A1
48 diabetes insipidus, nephrogenic, autosomal 9.9
49 endometriosis 9.9
50 diabetes insipidus 9.9

Comorbidity relations with Hydronephrosis via Phenotypic Disease Network (PDN): (show all 38)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Bladder Cancer
Bladder Neck Obstruction Candidiasis
Cervical Cancer Chronic Kidney Failure
Colorectal Cancer Cystitis
Cystitis Cystica Decubitus Ulcer
Deficiency Anemia Intestinal Obstruction
Iron Deficiency Anemia Kidney Disease
Nephrolithiasis, Uric Acid Nephrolithiasis, X-Linked Recessive, with Renal Failure
Nephrosclerosis Neurogenic Bladder
Neutropenia Ovarian Cancer
Paralytic Ileus Prostate Cancer
Prostatic Hypertrophy Protein-Energy Malnutrition
Pyelonephritis Radiation Cystitis
Rectal Neoplasm Rectosigmoid Junction Neoplasm
Renal Pelvis Carcinoma Ureter, Cancer of
Ureterolithiasis Urethral Benign Neoplasm
Urethral Calculus Urethral Stricture
Urinary Tract Obstruction Vesicoureteral Reflux 1

Graphical network of the top 20 diseases related to Hydronephrosis:



Diseases related to Hydronephrosis

Symptoms & Phenotypes for Hydronephrosis

MGI Mouse Phenotypes related to Hydronephrosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 10.13 B2M CCL2 CYP19A1 SLC12A1 EGF TGFB1
2 integument MP:0010771 10.1 RAB23 CYP19A1 SLC12A1 EGF TGFB1 MME
3 mortality/aging MP:0010768 10.1 B2M C12orf57 RAB23 SLC12A1 TGFB1 ALB
4 liver/biliary system MP:0005370 9.91 CYP19A1 TGFB1 MME ALB NAGLU B2M
5 renal/urinary system MP:0005367 9.86 CYP19A1 SLC12A1 TGFB1 ALB NAGLU AQP2
6 reproductive system MP:0005389 9.81 CYP19A1 SLC12A1 EGF TGFB1 AQP2 OSR1
7 skeleton MP:0005390 9.56 OSR1 RAB23 CYP19A1 SLC12A1 NAGLU ZIC3
8 vision/eye MP:0005391 9.17 OSR1 RAB23 CYP19A1 EGF NAGLU ZIC3

Drugs & Therapeutics for Hydronephrosis

Drugs for Hydronephrosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 85)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etomidate Approved Phase 4 33125-97-2 36339 667484
2
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
3
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
4
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
5
Silodosin Approved Phase 4 160970-54-7
6
Butyric Acid Experimental, Investigational Phase 4 107-92-6 264
7 Adjuvants, Anesthesia Phase 4
8 Anesthetics Phase 4,Not Applicable
9 Anesthetics, General Phase 4,Not Applicable
10 Anesthetics, Intravenous Phase 4,Not Applicable
11 Anti-Anxiety Agents Phase 4
12 Anti-Inflammatory Agents Phase 4,Not Applicable
13 Central Nervous System Depressants Phase 4,Not Applicable
14 Cortisol succinate Phase 4
15 GABA Agents Phase 4
16 GABA Modulators Phase 4
17 Hydrocortisone 17-butyrate 21-propionate Phase 4
18 Hydrocortisone acetate Phase 4
19 Hydrocortisone-17-butyrate Phase 4
20 Hypnotics and Sedatives Phase 4,Not Applicable
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
22 Psychotropic Drugs Phase 4
23 Tranquilizing Agents Phase 4
24 Adrenergic Agents Phase 4,Phase 3,Phase 2
25 Adrenergic alpha-1 Receptor Antagonists Phase 4,Phase 3,Phase 2
26 Adrenergic alpha-Antagonists Phase 4,Phase 3,Phase 2
27 Adrenergic Antagonists Phase 4,Phase 3,Phase 2
28
Alfuzosin Approved, Investigational Phase 3 81403-80-7 2092
29
Tamsulosin Approved, Investigational Phase 2, Phase 3 106133-20-4 129211
30
Abatacept Approved Phase 3 332348-12-6 10237
31
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
32 Pharmaceutical Solutions Phase 3
33 Antifungal Agents Phase 3
34 Anti-Infective Agents Phase 3,Phase 2,Not Applicable
35 Antirheumatic Agents Phase 3,Not Applicable
36 Calcineurin Inhibitors Phase 3
37 Cyclosporins Phase 3
38 Dermatologic Agents Phase 3
39 Immunosuppressive Agents Phase 3,Phase 2
40
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
41
Gemcitabine Approved Phase 2 95058-81-4 60750
42
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
43 Albumin-Bound Paclitaxel Phase 2
44 Antimetabolites Phase 2
45 Antimetabolites, Antineoplastic Phase 2
46 Antimitotic Agents Phase 2
47 Antineoplastic Agents, Phytogenic Phase 2
48 Antiviral Agents Phase 2
49 taxane Phase 2
50
Praziquantel Approved, Investigational, Vet_approved Not Applicable 55268-74-1 4891

Interventional clinical trials:

(show top 50) (show all 57)
# Name Status NCT ID Phase Drugs
1 Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children Unknown status NCT02013986 Phase 4 etomidate;midazolam;propofol
2 Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones Completed NCT01533389 Phase 4 Silodosin;Placebo
3 Alfuzosin Treatment in Children and Adolescents With Hydronephrosis of Neuropathic Etiology Completed NCT00576823 Phase 3 Alfuzosin
4 Study to Evaluate the Efficacy and Safety of Tamsulosin in Children With Neurogenic Bladder Completed NCT00796614 Phase 2, Phase 3 tamsulosin hydrochloride;Placebo
5 Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT) Completed NCT00256750 Phase 3 Cyclosporine (CsA);Belatacept LI (less intensive);Belatacept MI (more intensive)
6 Paclitaxel, Carboplatin and Gemcitabine in the Treatment of Patients With Advanced Transitional Cell Cancer of the Bladder Completed NCT00136175 Phase 2 Paclitaxel;Carboplatin;Gemcitabine
7 PK/PD, Long-term Safety and Efficacy of Tamsulosin Treatment in Children With Neurogenic Bladder Completed NCT00340704 Phase 2 tamsulosin hydrochloride
8 ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents. Recruiting NCT02933801 Phase 2 ODM-201
9 Sonographic Follow up in Newborns Diagnosed With Prenatal Hydronephrosis Unknown status NCT01780103
10 The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients Unknown status NCT01711996
11 Unilateral Cutaneous Ureterostomy - Long Term Follow up Unknown status NCT00546208
12 Initial Patient Evaluation in the Emergency Department With Point-of-Care Ultrasonography Unknown status NCT02099045
13 Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study Unknown status NCT00444431 Not Applicable
14 Keller Prehospital Ultrasound Study Unknown status NCT01074112
15 Hydronephrosis After Anterior Lumbar Interbody Fusion (ALIF) Completed NCT02976870 Not Applicable
16 Hydronephrosis on Ultrasound With CT Finding in Patients With Renal Colic Completed NCT01349244
17 Clinical Significance of Supranormal Differential Renal Function in the Recovery of Hydronephrosis Completed NCT01839006
18 Simplified Diagnostic Algorithm for Evaluation of Neonates With Prenatally Detected Hydronephrosis Completed NCT01330511
19 Hydronephrosis ARFI Study Completed NCT01781845 Not Applicable
20 Emergency Department Targeted Ultrasound for the Detection of Hydronephrosis Completed NCT00555308 Not Applicable
21 Prospective Pediatric Pyeloplasty Robotic Surgical Database Completed NCT00882544
22 Urinary Biomarkers as Predictors on Renal Function in Congenital Hydronephrosis Completed NCT00568724
23 Use of the PercSys MicroStent Device to Alleviate Ureteral Stone Symptoms and Hydronephrosis Completed NCT01637519
24 Emergency Department Ultrasound in Renal Colic Completed NCT01323842
25 Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique Completed NCT00231322 Not Applicable praziquantel
26 Evaluating Ureteral Length Using Computed Tomography (CT) Completed NCT01542593 Not Applicable
27 Dismembered Pyeloplasty With and Without After Coming Stent Completed NCT02138877 Not Applicable
28 Sensitivity and Specificity of NGAL in an Emergency Room Population Completed NCT00786708
29 Infection Among Patients Undergoing Radical Cystectomy. Completed NCT03290742
30 Study to Look for Artifact on Computed Tomography (CT) Representing Kidney Stones Completed NCT01187745
31 Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community Completed NCT00591968 Not Applicable
32 Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder Completed NCT03424499 Not Applicable
33 The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine Completed NCT00930046 Not Applicable
34 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage Completed NCT02055430 Not Applicable
35 Stepwise Shock Wave Lithotripsy in Pediatric Urolithiasis Completed NCT01807260 Not Applicable
36 Minimizing the Utilization of Voiding Cystourethrography for Patients With Antenatal Hydronephrosis Recruiting NCT02825485 Not Applicable
37 Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (LUTO) Recruiting NCT03281798 Not Applicable
38 Percutaneous Nephrostomy Versus Stent In Sepsis Trial Recruiting NCT02929160 Not Applicable
39 Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines Recruiting NCT00727974
40 Point-of-care Ultrasound in Finland Recruiting NCT03327688 Not Applicable
41 Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal Recruiting NCT02140970 Not Applicable Ibuprofen;Placebo
42 Sacral Nerve Stimulation in Improving Bladder After Acute Traumatic Spinal Cord Injury Recruiting NCT03083366 Not Applicable
43 Effectiveness of Antibiotics Versus Placebo to Treat Antenatal Hydronephrosis Active, not recruiting NCT01140516 Not Applicable Trimethoprim
44 Indwelling Stent Discoloration Project Active, not recruiting NCT02007980
45 Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors Active, not recruiting NCT02276924 Not Applicable
46 Ambulatory Blood Pressure Measurement in Children With Congenital Urine Flow Obstruction Available NCT00764543
47 Ureteral Reimplantation for the Treatment of Extrinsic Malignant Ureteral Obstruction Enrolling by invitation NCT02160652
48 Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder Enrolling by invitation NCT03108196 Not Applicable
49 Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program Enrolling by invitation NCT03296280
50 CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome Not yet recruiting NCT02812212 Not Applicable

Search NIH Clinical Center for Hydronephrosis

Cochrane evidence based reviews: hydronephrosis

Genetic Tests for Hydronephrosis

Genetic tests related to Hydronephrosis:

# Genetic test Affiliating Genes
1 Hydronephrosis 29

Anatomical Context for Hydronephrosis

MalaCards organs/tissues related to Hydronephrosis:

41
Kidney, Spinal Cord, Testis, Cervix, Prostate, Colon, Uterus

Publications for Hydronephrosis

Articles related to Hydronephrosis:

(show top 50) (show all 867)
# Title Authors Year
1
Featuring: Comparative effectiveness of a pilot patient-centered ultrasound report in the management of hydronephrosis. ( 29793741 )
2018
2
Severe fetal hydronephrosis: the added value of associated congenital anomalies of the kidneys and urinary tract (CAKUT) in the prediction of postnatal outcome. ( 29314159 )
2018
3
Unexpected Hydronephrosis: Mesenteric Fibromatosis. ( 29730360 )
2018
4
Influence of postnatal hydroureter in determining the need for voiding cystourethrogram in children with high-grade hydronephrosis. ( 29892489 )
2018
5
99mTc-DTPA Diuretic Renography with 3 hours late output fraction in the evaluation of hydronephrosis in children. ( 29368879 )
2018
6
Prenatal Hydronephrosis-Another Swing of the Pendulum? ( 29777653 )
2018
7
Correction to: Postnatal imaging of prenatally detected hydronephrosis-when is voiding cystourethrogram necessary? ( 29948311 )
2018
8
Pyonephrosis as the first symptom of congenital hydronephrosis in a 6-year old girl. ( 29775448 )
2018
9
The association between continuous antibiotic prophylaxis and UTI from birth until initial postnatal imaging evaluation among newborns with antenatal hydronephrosis. ( 29891187 )
2018
10
N-acetylcysteine ameliorates contrasta89induced kidney injury in rats with unilateral hydronephrosis. ( 29207099 )
2018
11
A unique case of bilateral hydronephrosis caused by a fecalith. ( 29375869 )
2018
12
Predictive Analytics and Modeling Employing Machine Learning Technology: The Next Step in Data Sharing, Analysis and Individualized Counseling Explored with A Large, Prospective Prenatal Hydronephrosis Database. ( 29964127 )
2018
13
Total Colpectomy Increases the Risk of Postoperative Hydronephrosis in Vaginal Cancer Patients. ( 29469636 )
2018
14
Comparison of the F+20 and F-15 Diuresis Technetium-99m Diethylenetriaminepentacetate Renography Protocols for Diagnosis of Ureteropelvic Junction Obstruction in Adult Patients with Hydronephrosis. ( 29430113 )
2018
15
Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and I^-ENaC abundance in rat kidney. ( 29767556 )
2018
16
Bilateral simultaneous "Santosh Post-graduate Institute tubularized flap pyelovesicostomy" in a case of bilateral pelvi-ureteric junction obstruction with bilateral giant hydronephrosis. ( 29785556 )
2018
17
Delayed hydronephrosis due to retroperitoneal hematoma after a seatbelt injury: A case report. ( 29879068 )
2018
18
Neonatal Circumcision and Urinary Tract Infections in Infants With Hydronephrosis. ( 29880703 )
2018
19
Bilateral hydronephrosis and acute kidney injury secondary to pelvis lipomatosis. ( 29524979 )
2018
20
Semaphorin-3A and Netrin-1 predict the development of kidney injury in children with congenital hydronephrosis. ( 29199452 )
2018
21
Comparison Characteristics of Family and Demographic of Children with Antenatal Hydronephrosis between 2<sup>nd</sup>and 3<sup>rd</sup>Trimesters of Gestation. ( 29445638 )
2018
22
Safe discharge parameters for patients with isolated antenatal hydronephrosis. ( 29859769 )
2018
23
Diabetic Cystopathy with Bilateral Hydronephrosis. ( 29425706 )
2018
24
Ultrasound Markers in Fetal Hydronephrosis to Predict Postnatal Surgery. ( 29975970 )
2018
25
Isolated low grade prenatally detected unilateral hydronephrosis: do we need long term follow-up? ( 29757579 )
2018
26
Abdominal pain as a result of intermittent hydronephrosis. ( 29863257 )
2018
27
Diagnostic accuracy of Onen's Alternative Grading System combined with Doppler evaluation of ureteral jets as an alternative in the diagnosis of obstructive hydronephrosis in children. ( 29796345 )
2018
28
Diuretic renography in hydronephrosis: a retrospective single-center study. ( 29797216 )
2018
29
The urologist and child hydronephrosis caused by ureteral anomalies. ( 29940628 )
2018
30
Bilateral Giant Hydronephrosis in a Ten-Year-Old Male. ( 29850342 )
2018
31
Hydronephrosis and risk of later development of hypertension. ( 29959876 )
2018
32
Outcomes of Ureteral Stent Placement for Hydronephrosis in Patients with Gynecological Malignancies. ( 28878594 )
2017
33
Bladder and Ureteral Dysfunction Leading to Hydronephrosis and Hydroureteronephrosis in Adults. ( 29287975 )
2017
34
Diuresis renography and ultrasonography in children with antenatally detected hydronephrosis can support diagnoses and suggest related surgery treatment. ( 29324912 )
2017
35
Technetium-99m-dimercaptosuccinic acid renal scintigraphy can guide clinical management in congenital hydronephrosis. ( 29324920 )
2017
36
Giant hydronephrosis: still a reality! ( 28861308 )
2017
37
Heterozygous Loss-of-Function Mutation in Odd Skipped Related 1 (Osr1) Is Associated with Vesico-Ureteric Reflux, Duplex Systems, and Hydronephrosis. ( 28724605 )
2017
38
Management of ureteral endometriosis with hydronephrosis: Experience from a tertiary medical center. ( 28707816 )
2017
39
Re: Incidence and Implications of Silent Hydronephrosis following Percutaneous Nephrolithotomy. ( 29144902 )
2017
40
Predicting Time to Reflux of Children With Antenatal Hydronephrosis: A Competing Risks Approach. ( 28918613 )
2017
41
Evaluation of postoperative hydronephrosis following semirigid ureteroscopy: Incidence and predictors. ( 28717542 )
2017
42
Impact of Pretreatment Hydronephrosis on the Success Rate of Shock Wave Lithotripsy in Patients with Ureteral Stone. ( 28792145 )
2017
43
Effective predictors for surgical decision in antenatal hydronephrosis: a prospective multiparameter analysis. ( 28861312 )
2017
44
Variable Resource Utilization in the Prenatal and Postnatal Management of Isolated Hydronephrosis. ( 28583878 )
2017
45
Does Mild Hydronephrosis Induced by Full-Bladder Improve Outcomes in Patients Undergoing Shock Wave Lithotripsy for Lower Calyceal Stones?: A Prospective Randomized Study. ( 29290087 )
2017
46
Changes in arterial pressure and markers of nitric oxide homeostasis and oxidative stress following surgical correction of hydronephrosis in children. ( 29196979 )
2017
47
Canadian Urological Association/Pediatric Urologists of Canada guidelines on the investigation and management of antenatally detected hydronephrosis. ( 29319488 )
2017
48
Severe hydronephrosis secondary to uterine artery pseudoaneurysm in the early second trimester of pregnancy: A case report. ( 28946860 )
2017
49
Serum and urinary thioredoxin concentrations are associated with severity of children hydronephrosis. ( 28111273 )
2017
50
Basidiobolomycosis complicated by hydronephrosis and a perinephric abscess presenting as a hypertensive emergency in a 7-year-old boy. ( 28112037 )
2017

Variations for Hydronephrosis

ClinVar genetic disease variations for Hydronephrosis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 C12orf57 NM_138425.3(C12orf57): c.53-2A> G single nucleotide variant Pathogenic rs1114167293 GRCh37 Chromosome 12, 7053637: 7053637
2 C12orf57 NM_138425.3(C12orf57): c.53-2A> G single nucleotide variant Pathogenic rs1114167293 GRCh38 Chromosome 12, 6944474: 6944474
3 46;XY;inv(6)(p22q13)dn inversion Pathogenic
4 SETBP1 NM_015559.2(SETBP1): c.2614G> A (p.Gly872Arg) single nucleotide variant Likely pathogenic GRCh38 Chromosome 18, 44951954: 44951954
5 SETBP1 NM_015559.2(SETBP1): c.2614G> A (p.Gly872Arg) single nucleotide variant Likely pathogenic GRCh37 Chromosome 18, 42531919: 42531919

Expression for Hydronephrosis

Search GEO for disease gene expression data for Hydronephrosis.

Pathways for Hydronephrosis

GO Terms for Hydronephrosis

Cellular components related to Hydronephrosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.65 ALB AQP2 B2M EGF ETFB MME
2 platelet alpha granule lumen GO:0031093 8.92 ALB EGF TGFB1 TIMP1

Biological processes related to Hydronephrosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 middle ear morphogenesis GO:0042474 9.16 NAGLU OSR1
2 cell activation GO:0001775 8.96 TGFB1 TIMP1
3 platelet degranulation GO:0002576 8.92 ALB EGF TGFB1 TIMP1

Sources for Hydronephrosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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