MCID: HYG001
MIFTS: 15

Hygroma Cervical

Categories: Immune diseases, Rare diseases

Aliases & Classifications for Hygroma Cervical

MalaCards integrated aliases for Hygroma Cervical:

Name: Hygroma Cervical 20
Cystic Hygroma of the Neck 20 6
Jugular Lymphatic Obstruction Sequence 20
Nuchal Lymphangioma 20
Hygroma Cervicis 20

Classifications:



Summaries for Hygroma Cervical

MalaCards based summary : Hygroma Cervical, also known as cystic hygroma of the neck, is related to cystic lymphangioma and down syndrome. An important gene associated with Hygroma Cervical is COL11A2 (Collagen Type XI Alpha 2 Chain). Affiliated tissues include tongue.

Related Diseases for Hygroma Cervical

Diseases related to Hygroma Cervical via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 cystic lymphangioma 10.9
2 down syndrome 10.3
3 lymphangioma 10.3
4 rare lymphatic malformation 10.3
5 hydrops fetalis, nonimmune 10.1
6 lymphatic malformation 7 10.1
7 ptosis 10.1
8 gonadal dysgenesis 10.1
9 turner syndrome 10.1
10 chromosomal triplication 10.1
11 lymphangiomatosis 10.1
12 aneurysm 10.1
13 rare vascular tumor 10.1
14 achondrogenesis, type ii 10.1
15 achondrogenesis 10.1
16 ventricular septal defect 10.1
17 heart septal defect 10.1
18 dwarfism 10.1

Graphical network of the top 20 diseases related to Hygroma Cervical:



Diseases related to Hygroma Cervical

Symptoms & Phenotypes for Hygroma Cervical

Drugs & Therapeutics for Hygroma Cervical

Search Clinical Trials , NIH Clinical Center for Hygroma Cervical

Genetic Tests for Hygroma Cervical

Anatomical Context for Hygroma Cervical

MalaCards organs/tissues related to Hygroma Cervical:

40
Tongue

Publications for Hygroma Cervical

Articles related to Hygroma Cervical:

(show top 50) (show all 59)
# Title Authors PMID Year
1
Dominant and recessive forms of fibrochondrogenesis resulting from mutations at a second locus, COL11A2. 6
22246659 2012
2
[Cystic hygroma of the neck in a young adult: about a case and literature review]. 61
32774629 2020
3
Cystic hygroma of the neck: single center experience and literature review. 61
29164568 2017
4
The Difficult Paediatric Airway: Two Cases of large Cystic Hygroma. 61
26894158 2016
5
An Interesting Association of Cystic Hygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue. 61
27069707 2016
6
Lymphatic Malformation in Newborns as the First Sign of Diffuse Lymphangiomatosis: Successful Treatment with Sirolimus. 61
26506225 2016
7
[A FETUS FROM VARNA WITH A CYSTIC HYGROMA OF THE NECK]. 61
26820013 2015
8
[PRENATAL DIAGNOSIS OF FOETAL TRISOMY 3Q WITH PATERNAL ORIGIN]. 61
26137780 2015
9
[Fetal anomalies in second trimester in recent ten years: clinical analysis of 116 cases]. 61
19595256 2009
10
US, CT and MRI findings in a case of diffuse lymphangiomatosis and cystic hygroma. 61
23396953 2008
11
Systemic lymphangiomatosis of bone involving the mandible with cystic hygroma of the neck. 61
16781353 2006
12
Cystic hygroma in a tactical aviator: a case report. 61
15646192 2004
13
Cystic hygroma of the neck: association with a growing venous aneurysm. 61
14625242 2003
14
Greenberg dysplasia (hydrops-ectopic calcification-moth-eaten skeletal dysplasia): prenatal ultrasound diagnosis and review of literature. 61
12210303 2002
15
[Neck branchial cleft fistula, cystic hygroma of the neck]. 61
11528737 2001
16
Cystic hygroma of the head and neck--a long-term follow-up of 44 cases. 61
10909034 2000
17
A huge cystic hygroma of the neck associated with intraventricular haemorrhage in a term neonate. 61
10229051 1999
18
Fetal akinesia deformation sequence in a highly developed acardius twin. 61
9354846 1997
19
Operating on placental support: the ex utero intrapartum treatment procedure. 61
9044127 1997
20
[Current aspects of cystic lymphangioma in the neck]. 61
7987449 1994
21
Magnetic resonance imaging in pregnancy: study of fetal cerebral malformations. 61
12797220 1994
22
[Cervical cystic lymphangiomas in adults]. 61
8408326 1993
23
[Cervical cystic lymphangioma in adults]. 61
8363299 1993
24
Familial cystic hygroma. Report of 8 cases in 3 families. 61
8110412 1993
25
[Prenatal diagnosis of cystic hygroma of the neck by echography. Case report. Review of the literature]. 61
1565949 1992
26
[Cystic hygroma of the neck. Antenatal diagnosis, prognostic factors, management. 42 cases]. 61
1885883 1991
27
Significance of cardiovascular malformations in cystic hygroma: a new interpretation of the pathogenesis. 61
2533851 1989
28
[Down's syndrome caused by robertsonian translocation with cystic hygroma]. 61
2534535 1989
29
Computed tomography of cervical cystic hygroma in the neck. 61
2807754 1989
30
First-trimester and early second-trimester diagnosis of nuchal cystic hygroma by transvaginal sonography: diverse prognosis of the septated from the nonseptated lesion. 61
2526584 1989
31
Congenital cystic hygroma of the neck diagnosed prenatally: outcome with normal and abnormal karyotype. 61
2657709 1989
32
[Cystic hygroma of the neck and non-immunologic hydrops fetalis]. 61
3309629 1987
33
Splenic lymphangiomatosis: a rare cause of splenomegaly. 61
3585671 1987
34
Antenatal sonographic diagnoses of giant cystic hygroma of the neck. A problem for the clinician. 61
3548211 1986
35
Lymphangioma in children. 61
6726854 1984
36
The significance of cystic hygroma in fetuses. 61
6693110 1984
37
CT diagnosis of cystic hygroma of the neck. 61
6841720 1983
38
Effectiveness of routine ultrasound in screening congenital defects. 61
7047712 1982
39
[Cystic hygroma of the neck]. 61
7415562 1980
40
Treatment of cystic hygroma. 61
982111 1976
41
[Cystic hygroma of the neck]. 61
941320 1976
42
[Cystic hygroma of the neck exploration with iodinated contrast media]. 61
1225160 1975
43
Massive infiltrating cystic hygroma of the neck in infancy. 61
4719107 1973
44
Cystic hygroma of the neck. 61
4683909 1973
45
The treatment of giant cystic hygroma of the neck. 61
4685310 1973
46
Surgical approach to cystic hygroma of the neck. 61
5443352 1970
47
[Rare vascular tumor of the neck: cystic hygroma of the neck]. 61
5522810 1970
48
Cystic hygroma of the neck. Report of a case. 61
6026963 1967
49
[On cystic hygroma of the neck]. 61
5932994 1966
50
[On cystic hygroma of the neck in infants. Considerations on 5 cases]. 61
5867365 1965

Variations for Hygroma Cervical

ClinVar genetic disease variations for Hygroma Cervical:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 COL11A2 NM_080680.3(COL11A2):c.966dup (p.Thr323fs) Duplication Likely pathogenic 497724 rs748440351 GRCh37: 6:33152074-33152075
GRCh38: 6:33184297-33184298
2 COL11A2 NM_080680.3(COL11A2):c.1773+8T>A SNV Uncertain significance 978633 GRCh37: 6:33146204-33146204
GRCh38: 6:33178427-33178427

Expression for Hygroma Cervical

Search GEO for disease gene expression data for Hygroma Cervical.

Pathways for Hygroma Cervical

GO Terms for Hygroma Cervical

Sources for Hygroma Cervical

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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