MCID: HYP767
MIFTS: 22

Hyperlexia

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Aliases & Classifications for Hyperlexia

MalaCards integrated aliases for Hyperlexia:

Name: Hyperlexia 57 71 75
Compulsive Reading 57
Precocious Reading 57

Characteristics:


Inheritance:

Autosomal recessive 57

OMIM®:

57 (Updated 24-Oct-2022)
Miscellaneous:
onset before age 5 years in the absence of instruction


External Ids:

OMIM® 57 238350
MedGen 40 C1855928
SNOMED-CT via HPO 69 408856003 408857007 43614003
UMLS 71 C1855928

Summaries for Hyperlexia

MalaCards based summary: Hyperlexia, also known as compulsive reading, is related to reading disorder and autism spectrum disorder. Affiliated tissues include cortex, cingulate cortex and brain, and related phenotype is autism.

Wikipedia: 75 Hyperlexia is a syndrome characterized by a child's precocious ability to read. It was initially... more...

More information from OMIM: 238350

Related Diseases for Hyperlexia

Diseases related to Hyperlexia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 reading disorder 10.5
2 autism spectrum disorder 10.5
3 autism 10.4
4 speech and communication disorders 10.3
5 pervasive developmental disorder 10.3
6 dyslexia 10.3
7 echolalia 10.2
8 dysphasia, familial developmental 10.0
9 aphasia 10.0
10 learning disability 10.0
11 toe syndactyly, telecanthus, and anogenital and renal malformations 9.9
12 gilles de la tourette syndrome 9.9
13 hand skill, relative 9.9
14 prader-willi syndrome 9.9
15 stroke, ischemic 9.9
16 west syndrome 9.9
17 apraxia 9.9
18 specific language impairment 9.9
19 ideomotor apraxia 9.9
20 hashimoto encephalopathy 9.9
21 encephalopathy 9.9
22 specific language disorder 9.9

Graphical network of the top 20 diseases related to Hyperlexia:



Diseases related to Hyperlexia

Symptoms & Phenotypes for Hyperlexia

Human phenotypes related to Hyperlexia:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 autism 30 HP:0000717

Symptoms via clinical synopsis from OMIM®:

57 (Updated 24-Oct-2022)
Neurologic Behavioral Psychiatric Manifestations:
autism
developmental disorder of communication
pervasive developmental disorder
precocious reading
reading at level beyond mental age
more

Clinical features from OMIM®:

238350 (Updated 24-Oct-2022)

Drugs & Therapeutics for Hyperlexia

Search Clinical Trials, NIH Clinical Center for Hyperlexia

Genetic Tests for Hyperlexia

Anatomical Context for Hyperlexia

Organs/tissues related to Hyperlexia:

MalaCards : Cortex, Cingulate Cortex, Brain

Publications for Hyperlexia

Articles related to Hyperlexia:

(show top 50) (show all 76)
# Title Authors PMID Year
1
The neural basis of hyperlexic reading: an FMRI case study. 62 57
14715131 2004
2
Familial pervasive development disorder, Tourette disorder and hyperlexia. 62 57
3226648 1988
3
Inquiry into the incidence of hyperlexia in a statewide population of children with pervasive developmental disorder. 62 57
4048337 1985
4
Hyperlexia--specific word recognition skills in young children. 62 57
6066378 1967
5
Early Reading Comprehension Intervention for Preschoolers with Autism Spectrum Disorder and Hyperlexia. 62
34046778 2022
6
Is it hyperlexia? Toward a deeper understanding of precocious reading skills in two cases of children with Autism Spectrum Disorder. 62
35147641 2022
7
Correction to: Early Word Reading of Preschoolers with ASD, Both With and Without Hyperlexia, Compared to Typically Developing Preschoolers. 62
32930892 2021
8
Early Word Reading of Preschoolers with ASD, Both With and Without Hyperlexia, Compared to Typically Developing Preschoolers. 62
32783105 2021
9
Developmental changes in the cognitive and educational profiles of children and adolescents with 22q11.2 deletion syndrome. 62
28247486 2018
10
Hyperlexia: Systematic review, neurocognitive modelling, and outcome. 62
28478182 2017
11
Compulsive reading: Stars with addictions, to Star Wars. 62
27493227 2016
12
Reading and math achievement profiles and longitudinal growth trajectories of children with an autism spectrum disorder. 62
24449604 2015
13
A girl with tuberous sclerosis complex presenting with severe epilepsy and electrical status epilepticus during sleep, and with high-functioning autism and mutism. 62
24968009 2014
14
Savant syndrome: realities, myths and misconceptions. 62
23918440 2014
15
What are the mechanisms behind exceptional word reading ability in hyperlexia?: Evidence from a 4-year-old hyperlexic boy's invented spellings. 62
23722887 2013
16
The development of a multimedia online language assessment tool for young children with autism. 62
23962602 2013
17
Veridical mapping in the development of exceptional autistic abilities. 62
23219745 2013
18
Reading skills in children diagnosed with hyperlexia: case reports. 62
24408490 2013
19
Compulsive reading. 62
22927098 2012
20
Enhanced visual functioning in autism: an ALE meta-analysis. 62
21465627 2012
21
Hyperlexia III: separating 'autistic-like' behaviors from autistic disorder; assessing children who read early or speak late. 62
22324205 2011
22
Developmental dissociations between lexical reading and comprehension: evidence from two cases of hyperlexia. 62
20678759 2010
23
Dyslexia and hyperlexia in bilinguals. 62
20440742 2010
24
Hyperlexia and ambient echolalia in a case of cerebral infarction of the left anterior cingulate cortex and corpus callosum. 62
19585352 2009
25
Hyperlexia in children with autism spectrum disorders. 62
17048093 2007
26
[Asperger's syndrome, little teachers: special skills]. 62
17347944 2007
27
Hyperlexia in Spanish-speaking children: report of 2 cases from Colombia, South America. 62
16843492 2006
28
Patterns of reading ability in children with autism spectrum disorder. 62
16897396 2006
29
[Hyperlexia and pseudotetanus in Hashimoto's encephalopathy]. 62
16883515 2006
30
Developmental and acquired dyslexias. 62
17131596 2006
31
A mechanism of implicit lexicalized phonological recoding used concurrently with underdeveloped explicit letter-sound skills in both precocious and normal reading development. 62
14667699 2004
32
Annotation: Hyperlexia: disability or superability? 62
14626452 2003
33
Hyperlexia profiles. 62
12590912 2003
34
[Autism and hyperlexia]. 62
12599104 2003
35
Fluoxetine response in children with autistic spectrum disorders: correlation with familial major affective disorder and intellectual achievement. 62
12418789 2002
36
Learning disability subtypes: classification of high functioning hyperlexia. 62
12174811 2002
37
A descriptive study of hyperlexia in a clinically referred sample of children with developmental delays. 62
11916330 2002
38
[A dynamic neuropsychological approach]. 62
11464476 2000
39
[Hyperlexia in an adult patient with lesions in the left medial frontal lobe]. 62
10967660 2000
40
Foreign language learning, hyperlexia, and early word recognition. 62
20563785 2000
41
Reading skills in hyperlexia: a developmental perspective. 62
10349355 1999
42
Sniffing behaviour, or recognizing a lily by smell, but not recognizing a sock on sight. 62
9339337 1997
43
Semantic memory impairment does not impact on phonological and orthographic processing in a case of developmental hyperlexia. 62
9027372 1997
44
Neuropsychological profiles of children diagnosed as specific language impaired with and without hyperlexia. 62
14588414 1997
45
Reading skills in children with Turner's syndrome: an analysis of hyperplexia. 62
8800619 1996
46
Autism with hyperlexia: a distinct syndrome? 62
8373566 1993
47
Brief report: implications of hyperlexia in an autistic savant. 62
8331055 1993
48
[Environmental dependence in brain lesions: imitative behavior, prehension and utilization]. 62
1375781 1992
49
Semantic-pragmatic disorder: a right hemisphere syndrome? 62
1814422 1991
50
West syndrome associated with hyperlexia. 62
2242178 1990

Variations for Hyperlexia

Expression for Hyperlexia

Search GEO for disease gene expression data for Hyperlexia.

Pathways for Hyperlexia

GO Terms for Hyperlexia

Sources for Hyperlexia

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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